URAT1 inhibitor11 (Compound 7) is a potent URAT1 inhibitor, exhibiting an IC50 of 0.18 μM. It effectively reduces uric acid levels in zebrafish with hyperuricemia induced by Potassium oxonate and Xanthinesodium salt.

URAT1 inhibitor 11 (60 min) 在小鼠肝微粒体中的稳定性优于 Benzbromarone，残留率分别为83.2% 和 4.5%。

URAT1 inhibitor 11 (0.5 μM) 对由 Potassium oxonate 和 Xanthine sodium salt 诱导的高尿酸血症斑马鱼显示出降尿酸作用，能够降低其血液中的尿酸水平。