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Search Results for " anticancer "

Targets Recommended: Others

1264

抑制剂 & 化合物

325

天然产物

20

化合物库

16

重组蛋白

3

同位素标记化合物

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Cat. No.	Product Name
L2100	抗癌化合物库		7234 compounds
	7234 种肿瘤相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L2180	抗肿瘤库Plus		1468 compounds
	1468 种抗肿瘤相关、结构新颖的化合物；
L2150	抗癌药物库		3080 compounds
	3080 个具有抗癌活性小分子的独特集合，生物活性已经临床前实验证实，可用于高通量、高内涵筛选；
L2110	抗癌上市药物库		1779 compounds
	1779 个具有抗癌活性小分子的独特集合，所有化合物都经过了严格的临床前研究和临床试验，由FDA、EMA 或NMPA 批准上市，可用于高通量、高内涵筛选。
L2130	抗癌细胞代谢库		1268 compounds
	1268 种癌细胞代谢相关的生物活性小分子化合物的特有集合，用于肿瘤相关的研究以及抗肿瘤药物的筛选，用于高通量、高内涵筛选；
L2160	抗癌活性化合物库		3188 compounds
	3188 种具有抗肿瘤活性的化合物的特有集合，用于高通量、高内涵筛选；
L2120	抗癌临床化合物库		2545 compounds
	2545 个具有抗癌活性小分子的独特集合，可用于高通量高内涵筛选。
L6900	稀有天然产物库		693 compounds
	693 种稀有天然产物的集合，可以用于高通量和高内涵筛选；
L1110	微管靶向化合物库		142 compounds
	142 种靶向微管的分子集合，用于高通量筛选和高内涵筛选；
L2151	化疗药物库		48 compounds
	48 个肿瘤化疗药物，可以用于高通量和高内涵筛选；
L6110	生物碱类天然产物库		500 compounds
	500 种生物碱类天然产物的独特集合，可用于高通量筛选和高内涵筛选；
NY1000	天然产物衍生物库		4000 compounds
	22个天然产物骨架，3745个天然产物衍生物；
L6100	天然多酚类化合物库		635 compounds
	635 个天然多酚化合物的独特集合，可用于高通量、高内涵筛选；
L6130	萜类天然产物库		622 compounds
	622 种萜类天然产物的独特集合，可用于高通量筛选和高内涵筛选；
L6700	抗癌天然产物库		1772 compounds
	1772 种已知活性天然产物的独特集合，是肿瘤药物开发、抗癌先导化合物筛选等领域的有力工具，可用于HTS 和HCS。
L1100	蛋白酶抑制剂库		343 compounds
	343 种已知的小分子蛋白酶抑制剂的特有集合，可用于高通量筛选和高内涵筛选；
L5100	含氟化合物库		574 compounds
	574 个含氟化合物的独特集合，可用于高通量筛选和高内涵筛选；
L9240	农药化合物库		270 compounds
	270种农药相关化合物的独特集合，可用于高通量筛选和高内涵筛选；
L6020	天然产物单体化合物库		16627 compounds
	16627 种精选天然产物集合，结构多样，遍布多种动植物与微生物；
L6820	烟草单体化合物库		747 compounds
	747种烟草单体化合物的独特集合，可用于高通量筛选和高内涵筛选

化合物库

抗癌化合物库

Cat.No: L2100

Compounds: 7234

抗肿瘤库Plus

Cat.No: L2180

Compounds: 1468

抗癌药物库

Cat.No: L2150

Compounds: 3080

抗癌上市药物库

Cat.No: L2110

Compounds: 1779

抗癌细胞代谢库

Cat.No: L2130

Compounds: 1268

抗癌活性化合物库

Cat.No: L2160

Compounds: 3188

抗癌临床化合物库

Cat.No: L2120

Compounds: 2545

稀有天然产物库

Cat.No: L6900

Compounds: 693

微管靶向化合物库

Cat.No: L1110

Compounds: 142

化疗药物库

Cat.No: L2151

Compounds: 48

生物碱类天然产物库

Cat.No: L6110

Compounds: 500

天然产物衍生物库

Cat.No: NY1000

Compounds: 4000

天然多酚类化合物库

Cat.No: L6100

Compounds: 635

萜类天然产物库

Cat.No: L6130

Compounds: 622

抗癌天然产物库

Cat.No: L6700

Compounds: 1772

蛋白酶抑制剂库

Cat.No: L1100

Compounds: 343

含氟化合物库

Cat.No: L5100

Compounds: 574

农药化合物库

Cat.No: L9240

Compounds: 270

天然产物单体化合物库

Cat.No: L6020

Compounds: 16627

烟草单体化合物库

Cat.No: L6820

Compounds: 747

Cat. No.	Product Name	Target	Signaling Pathways
T39868	Anticancer agent 11	Others	Others
	Anticancer agent 11 an effective broad-spectrum anticancer agent, exerts its therapeutic potential by suppressing angiogenesis and facilitating the formation of DNA cross-links.
T60420	Anticancer agent 73	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Anticancer agent 73 是一种抗癌剂，它能有效地靶向反式激活反应（TAR）RNA 结合蛋白2（TRBP），并破坏TRBP-Dicer 的相互作用。Anticancer agent 73 通过调节 HCC 细胞中 miRNA 组和蛋白质组的表达谱，在体外和体内抑制 HCC 的生长和转移。
T60852	Anticancer agent 46	Others	Others
	Anticancer agent 46是一种有效的抗癌剂，在细胞实验中显示出抗增殖活性，对 MGC803细胞的 IC50为0.986μM。
T61046	Anticancer agent 43	Apoptosis	Apoptosis
	Anticancer agent 43 是一种有效的抗癌剂，通过 caspase 3， PARP1，Bax 蛋白依赖性途径诱导癌细胞凋亡 (apoptosis)。Anticancer agent 43 能够诱导 DNA 损伤，可用于研究大鼠胶质母细胞瘤。
T40479	Anticancer agent 13	Others	Others
	Anticancer agent 13 is an anticancer agent from dicarboxylic acids and amines.
T39501	Anticancer agent 7	Others	Others
	Anticancer agent 7 (Example 5) is an anti-cancer agent that exhibits potent anticancer activity against H1650 lung cancer cells, with an IC50 value of 5 μM.
T40330	Anticancer agent 15	Others	Others
	Anticancer agent 15, an anticancer agent, exerts its efficacy by elevating intracellular levels of reactive oxygen species (ROS) and inducing cell death in melanoma cancer cells through necroptosis.
T10331	Anticancer agent 3	Others	Others
	Anticancer agent 3 (Compound 4) is a anti-cancer agent.
T27998	MDK-4204 Anticancer AgentI,MDK 4204,Anticancer Agent I,MDK4204,Anticancer Agent-I	Others	Others
	MDK-4204, an anticancer agent, shows significant anti-cancer activity with IC50 values of 8.8 µM and 9.5 µM in PC-3 and DU-145 cells, respectively.
T62667	Anticancer agent 51	Others	Others
	Anticancer agent 51 (compound 3d) 是一种有效的抗癌剂 (Ki: 731.62 nM)，具有抗癌活性。Anticancer agent 51 具有潜力进行前列腺癌的研究。
T64002	Anticancer agent 61	Others	Others
	Anticancer agent 61 是一种口服具有活力的抗癌剂。Anticancer agent 61 能够抗 HepG2、Bel-7402 和 MCF-7 癌细胞的增殖，他们的 IC50 值分别为 1.12、1.97 和 1.08 μM。Anticancer agent 61 能够抑制肿瘤生长。
T72502	Anticancer agent 92	Others	Others
	Anticancer agent 92 是一种对非癌细胞无毒的抗癌剂。
T61412	Anticancer agent 47	Others	Others
	Anticancer agent 47 (compound 4j) exhibits potent anticancer properties, demonstrating antiproliferative activities and inducing apoptosis as well as cell cycle arrest at G0/G1 phase. Moreover, Anticancer agent 47 has exhibited significant in vivo antitumor activities [1].
T62124	Anticancer agent 80	Others	Others
	Anticancer agent 80 (Compound 3c) 是一种抗癌剂。Anticancer agent 80 对 T47-D 表现出明显的暗毒性作用 (IC50: 10.14 μM)。
T63982	Anticancer agent 50	Others	Others
	Anticancer agent 50 (compound 6) 是 ABCB1 外排泵的有效调节剂，具有细胞毒活性和抗增殖活性。Anticancer agent 50 能够减少细胞周期蛋白 D1 的表达，并诱导 p53 表达。Anticancer agent 50 对 T 淋巴瘤表现出研究潜力。
T61379	Anticancer agent 30	Others	Others
	Anticancer agent 30 (compound 6f-Z) is a potent anticancer compound. It belongs to the class of 3-arylidene-2-oxindole derivatives and acts as a selective inhibitor of CDK2. Extensive research has demonstrated its significant anticancer activity, making it a promising candidate for cancer treatment [1].
T78929	Anticancer agent 126	Histone Methyltransferase	Chromatin/Epigenetic
	Anticanceragent 126 (compound 12) 作为WDR5抑制剂，能够破坏WDR5-MYC间的相互作用，并降低MYC靶基因的表达，表现出其抗癌活性。
T60776	Anticancer agent 68	Others	Others
	Anticancer agent 68 is (Compound 12) 是一种抗癌剂。Anticancer agent 68 将细胞阻滞在 G2/M 期并诱导程序性细胞死亡。Anticancer agent 68 通过激活 p53 和 PTEN 诱导上调肿瘤抑制。
T64179	Anticancer agent 65	Others	Others
	Anticancer agent 65 在肿瘤细胞系中显示出良好的效果，尤其是 A549 细胞 (IC50: 1.07 μM)。Anticancer agent 65 能够将 A549 细胞的细胞周期阻滞在 S 期，诱导细胞凋亡，增加 p53、p21 的表达水平，并促使 ROS 生成和 MMP 崩溃。
T83093	Anticancer agent 107	Others	Others
	Anticancer agent 107(Compd 11jc) 具有显著的抗肿瘤活性，是研究肺转移性黑色素瘤的潜在抗癌剂。
T79301	Anticancer agent 140	Parasite	Microbiology/Virology
	Anticanceragent 140（Compd 3）是一种化合物，具备潜在的抗癌和抗寄生虫活性。
T79482	Anticancer agent 137	PI3K	PI3K/Akt/mTOR signaling
	Anticanceragent 137 (8q) 是一种高效的 PI3k 抑制剂，展现出广谱的抗肿瘤活性。它能够诱导 G2/M 阶段的细胞周期阻滞与细胞凋亡（apoptosis），并促进 PARP、caspase 3 和 caspase 7 的裂解。该化合物主要用于癌症相关的生物医学研究。
T79844	Anticancer agent 143	Phosphatase	Metabolism
	Anticanceragent 143（化合物 369），作为PTPN2/PTP1B双重抑制剂，表现出强效活性，其IC50值均低于2.5 nM。该化合物主要用于癌症研究领域。
T79202	Anticancer agent 118	Others	Others
	Anticanceragent 118是一种N-酰化环丙沙星衍生物，展现了针对革兰氏阳性(bacterial)菌株的高度活性，以及对前列腺癌PC3细胞的抗增殖能力，适用于抗肿瘤研究。
T78780	Anticancer agent 139	Others	Others
	Anticanceragent 139（Compound 6h）展现了针对多种癌细胞株的抗癌效能。该化合物能够与Tubulin的Lys352残基发生π-阳离子相互作用。在对SNB-19、OVCAR-8和NCI-H460细胞株的测试中，Anticanceragent 139展现出较高的生长抑制率（PGI），数值分别为86.61、85.26和75.99。同时，该化合物对于HOP-62、SNB-75、ACHN、NCI/ADR-RES、786-O、A549/ATCC、HCT-116以及MDA-MB-231细胞株亦表现出中等的生长抑制作用，其PGI值分别为67.55、65.46、59.09、59.02、57.88、56.88、56.53和56.4、51.88。
T83078	Anticancer agent 33	Others	Others
	Anticanceragent 33 (compound 3) 为Squamocin与Bullatacin衍生物，展现出有效的抗癌特性。本化合物对4T1乳腺癌细胞系（包括A549、HeLa、HepG2和MCF-7细胞）的生长抑制作用显著，其IC50范围为1.9-5.4 µM。
T83087	Anticancer agent 158	Others	Others
	Anticanceragent 158 (compound 7c) 作为一种有效的抗癌剂，其对HepG-2、MDA-MB-231、HCT-116细胞系的IC50值分别为7.93 μM、9.28 μM、13.28 μM。
T62601	Anticancer agent 48	Others	Others
	Anticancer agent 48 (compound 48) 是一种广谱抗癌剂，其表现出抗增殖活性。Anticancer agent 48 对微管蛋白聚合具有抑制作用。Anticancer agent 48 在体内显示抗肿瘤活性。Anticancer agent 48 具有潜力进行实体瘤和血液肿瘤的研究。主语
T61777	Anticancer agent 42	Others	Others
	Anticancer agent 42 (compound 10d) is an orally active, potent anticancer agent with demonstrated efficacy against MDA-MB-231 cells, exhibiting an IC50 of 0.07 μM. It exerts its anticancer activity through the activation of apoptotic pathways and p53 expression. Anticancer agent 42 is a valuable tool for investigating metastatic breast cancer [1].
T61750	Anticancer agent 72	Others	Others
	Anticancer agent 72 (compound 8c) effectively inhibits the K+ channel, displaying significant potential as an anticancer treatment. Additionally, it induces apoptosis, a programmed cell death process [1].
T63587	Anticancer agent 45	Others	Others
	Anticancer agent 46 是有效的、选择性的抗癌剂，能够诱导细胞凋亡 (apoptosis)。Anticancer agent 46 在癌细胞中表现出细胞毒效果，对人血的活化淋巴细胞显示出低毒性。
T63913	Anticancer agent 41	Others	Others
	Anticancer agent 41 是一种有效的抗癌剂，对 MDA-MB-231 细胞表现出良好的抗肿瘤效果 (IC50: 3.99 μM)。
T63917	Anticancer agent 67	Others	Others
	Anticancer agent 67 是环丙沙星类似物，是一种抗癌剂，在 MCF-7 细胞中能够诱导细胞凋亡 (apoptosis) 并增加亚 G1 细胞群。
T63671	Anticancer agent 60	Others	Others
	Anticancer agent 60 对人 HepG2 细胞具有抗增殖效果，其 IC50 值为 4.13 μM。在人 HepG2 异种移植小鼠模型中，Anticancer agent 60 表现出抗肿瘤活性。
T63159	Anticancer agent 28	Others	Others
	Anticancer agent 28 在体内 H22 同种异体移植小鼠中具有良好的抗肿瘤作用。Anticancer agent 28 对 K562 细胞的作用是 Oridonin 的50倍，其 IC50 值为 0.09 μM。
T79204	Anticancer agent 122	Others	Others
	Anticanceragent 122，作为一种hLDHA抑制剂，表现出显著的抗癌活性，主要应用于抗肿瘤研究。
T63354	Anticancer agent 17	Others	Others
	Anticancer agent 17 对 HeLa 细胞 (IC50: 0.19 μM) 和 A2780 细胞 (IC50: 0.09 μM) 具有有效抗癌作用。
T61673	Anticancer agent 56	Others	Others
	Anticancer agent 56 (compound 4d) is a powerful anti-cancer compound with favorable drug-like properties. It shows significant anticancer activity against multiple cancer cell lines, with an IC50 value of less than 3 μM. Anticancer agent 56 exerts its effects by causing cell cycle arrest at the G2/M phase and activating the mitochondrial apoptosis pathway. Mechanistically, it induces the accumulation of reactive oxygen species (ROS), upregulates BAX, downregulates Bcl-2, and triggers the activat...
T83080	Anticancer agent 171	Others	Others
	Anticanceragent 171（Compound 6a）是一款肟类似物，对HCT116细胞表现出显著的抗癌活性，IC50值为3.43 μM，主要用于癌症研究领域。
T78957	Anticancer agent 105	Apoptosis	Apoptosis
	Anticanceragent 105 是基于噻吩嘧啶支架的抗癌化合物，显示出高度的安全性与抗肿瘤活性。该化合物对黑色素瘤细胞表现出选择性毒性，并能诱导细胞凋亡（apoptosis）。在肺转移性黑色素瘤小鼠模型中，Anticanceragent 105 能够显著地抑制转移性结节的形成。
T83084	Anticancer agent 162	Others	Others
	Anticanceragent 162 (compound 1d)作为一种抗癌药物，显示出亲脂性和针对性细胞毒性，能够特异性诱导Hela细胞系的癌细胞死亡。
T83075	Anticancer agent 94	Others	Others
	Anticanceragent 94, 一种4-羟基香豆素衍生物，能抑制肺癌细胞的侵袭和迁移，其机制为调节(EMT)效应子表达。
T83076	Anticancer agent 93	Others	Others
	Anticanceragent 93, 一种4-羟基香豆素衍生物，能够抑制肺癌细胞的侵袭与迁移，其机制为调节上皮间质转化（EMT）效应子的表达。
T83090	Anticancer agent 131	Others	Others
	HCT-116-IN-1, 一种与γ-内酰胺融合的吡啶酮衍生物，展现了针对HCT116细胞的强抗癌活性，其细胞毒性测定显示IC50值为5.59 μM。
T79359	Anticancer agent 147	Ferroptosis	Apoptosis
	Anticanceragent 147（化合物6j），作为槐定碱的衍生物，功能为铁死亡（Ferroptosis）诱导剂。该化合物能促进Fe2+、活性氧（ROS）及丙二醛（MDA）在细胞内的积累，并通过增加内质网（ER）应激和上调转录因子ATF3的表达发挥作用。在体外及体内实验中，Anticanceragent 147展现了出色的抗肝癌活性。
T79388	Anticancer agent 154	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	Anticanceragent 154 (Compound 8h) 增加活性氧水平、导致线粒体损伤，并诱导细胞凋亡和 DNA 损伤。此外，该化合物通过降低 GSH 和 GPX4 水平，增加脂质过氧化，进而诱导铁死亡。Anticanceragent 154 对多种癌细胞株（HT29、H1975、A549 及 MCF-7）显示抑制作用，IC50 值在 1.0-1.9 μM 范围。
T62427	Anticancer agent 32	Others	Others
	Anticancer agent 32 (compound 2g) 是一种抗癌剂。Anticancer agent 32 能够影响细胞周期并诱导细胞凋亡，表现出抗癌效果。Anticancer agent 32 能够用于研究癌症。
T62602	Anticancer agent 49	Others	Others
	Anticancer agent 49 (compound 69) 是一种广谱抗癌剂，其表现出抗增殖活性。Anticancer agent 49 对微管蛋白聚合具有抑制作用。Anticancer agent 49 在体内显示抗肿瘤活性。Anticancer agent 49 具有潜力进行实体瘤和血液肿瘤的研究。
T61230	Anticancer agent 74	Others	Others
	Anticancer agent 74 exhibits moderate anticancer activity with lower selectivity and cytotoxicity compared to doxorubicin towards normal cells [1].
T63599	Anticancer agent 54	Others	Others
	Anticancer agent 54 是有效的抗癌剂，其抗癌活性取决于 DNA 嵌入和 ROS 生成。 Anticancer agent 54 能够将细胞周期阻滞在 G0/G1 期，并诱导细胞凋亡 (apoptosis)，具有抗增殖效果。

化合物

Anticancer agent 11

Cat.No: T39868

Target: Others

Anticancer agent 73

Cat.No: T60420

Target: DNA/RNA Synthesis

Anticancer agent 46

Cat.No: T60852

Target: Others

Anticancer agent 43

Cat.No: T61046

Target: Apoptosis

Anticancer agent 13

Cat.No: T40479

Target: Others

Anticancer agent 7

Cat.No: T39501

Target: Others

Anticancer agent 15

Cat.No: T40330

Target: Others

Anticancer agent 3

Cat.No: T10331

Target: Others

Cat.No: T27998

Synonym: Anticancer AgentI,MDK 4204,Anticancer Agent I,MDK4204,Anticancer Agent-I

Target: Others

Anticancer agent 51

Cat.No: T62667

Target: Others

Anticancer agent 61

Cat.No: T64002

Target: Others

Anticancer agent 92

Cat.No: T72502

Target: Others

Anticancer agent 47

Cat.No: T61412

Target: Others

Anticancer agent 80

Cat.No: T62124

Target: Others

Anticancer agent 50

Cat.No: T63982

Target: Others

Anticancer agent 30

Cat.No: T61379

Target: Others

Anticancer agent 126

Cat.No: T78929

Target: Histone Methyltransferase

Anticancer agent 68

Cat.No: T60776

Target: Others

Anticancer agent 65

Cat.No: T64179

Target: Others

Anticancer agent 107

Cat.No: T83093

Target: Others

Anticancer agent 140

Cat.No: T79301

Target: Parasite

Anticancer agent 137

Cat.No: T79482

Target: PI3K

Anticancer agent 143

Cat.No: T79844

Target: Phosphatase

Anticancer agent 118

Cat.No: T79202

Target: Others

Anticancer agent 139

Cat.No: T78780

Target: Others

Anticancer agent 33

Cat.No: T83078

Target: Others

Anticancer agent 158

Cat.No: T83087

Target: Others

Anticancer agent 48

Cat.No: T62601

Target: Others

Anticancer agent 42

Cat.No: T61777

Target: Others

Anticancer agent 72

Cat.No: T61750

Target: Others

Anticancer agent 45

Cat.No: T63587

Target: Others

Anticancer agent 41

Cat.No: T63913

Target: Others

Anticancer agent 67

Cat.No: T63917

Target: Others

Anticancer agent 60

Cat.No: T63671

Target: Others

Anticancer agent 28

Cat.No: T63159

Target: Others

Anticancer agent 122

Cat.No: T79204

Target: Others

Anticancer agent 17

Cat.No: T63354

Target: Others

Anticancer agent 56

Cat.No: T61673

Target: Others

Anticancer agent 171

Cat.No: T83080

Target: Others

Anticancer agent 105

Cat.No: T78957

Target: Apoptosis

Anticancer agent 162

Cat.No: T83084

Target: Others

Anticancer agent 94

Cat.No: T83075

Target: Others

Anticancer agent 93

Cat.No: T83076

Target: Others

Anticancer agent 131

Cat.No: T83090

Target: Others

Anticancer agent 147

Cat.No: T79359

Target: Ferroptosis

Anticancer agent 154

Cat.No: T79388

Target: Reactive Oxygen Species

Anticancer agent 32

Cat.No: T62427

Target: Others

Anticancer agent 49

Cat.No: T62602

Target: Others

Anticancer agent 74

Cat.No: T61230

Target: Others

Anticancer agent 54

Cat.No: T63599

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T83089	Anticancer agent 149
	Anticanceragent 149 (compound 3) 是一种从薯蓣 (DM) 根茎中分离出的抗癌剂，其对MCF-7 细胞呈现选择性细胞毒活性，特有IC50值为31.41 μM。
T83073	Anticancer agent 96
	Anticanceragent 96 (Compound 4) 对人癌细胞表现出显著的细胞毒性。
T83086	Anticancer agent 160	Others	Others
	Anticanceragent 160 (Compound 6)，源自Parthenium hysterophorus的天然化合物，对HCT-116细胞表现出细胞毒作用，其半数抑制浓度（IC50）为5.0 μM。
T83088	Anticancer agent 156
	Anticanceragent 156（compound 11）是一种基于Miliusanes的强效抗癌剂，有效抑制人源癌细胞生长，并对胃癌细胞展现出显著细胞毒性。
TN1873	Lirinidine	Others; Antioxidant	Others; oxidation-reduction
	Lirinidine 是一种分离自L. tulipifera叶片生物碱，具有抗氧化 (antioxidant) 和抗癌作用。它在体外表现出中等的铁还原能力和较小的自由基清除能力，可用于研究化妆品。
T9144	Telekin	Others	Others
	Telekin 是一种从中草药 Carpesium divaricatum 中分离出来的 eudesmane 型倍半萜内酯化合物，据报道可强烈抑制癌细胞的增殖。
T21065	Artemisitene	Others	Others
	Artemisitene 是青蒿素的氧化形式，是一种抗疟药。青蒿素前体是青蒿素生物合成的重要基础物质，包括青蒿素 B、青蒿素、青蒿酸等。
T10668	Camalexin	Reactive Oxygen Species; ROS; Antibacterial; Antifungal	Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
	Camalexin 是从Camelina sativa 和Arabidopsis 中分离出来的一种植物抗毒素，可诱导活性氧的产生，具有抗菌、抗真菌、抗增殖和抗癌活性。
TN6771	Malabaricone B	Others	Others
	Malabaricone B 是一种源自香料的酚类物质，它通过不依赖 p53 的途径诱导肺癌细胞中的线粒体损伤。
TN6739	Angoline 6-Methoxyldihydrochelerythrine	IL Receptor; STAT	Immunology/Inflammation; JAK/STAT signaling; Stem Cells
	Angoline (6-Methoxyldihydrochelerythrine) 是选择性 IL6/STAT3信号通路的抑制剂，IC50为 11.56 μM。它抑制 STAT3 磷酸化及其靶基因表达，并抑制癌细胞增殖。
TN1079	Deoxyelephantopin	NF-κB	NF-κB
	Deoxyelephantopin 是来自Elephantopus scaber 的，具有生物活性的天然倍半萜烯内酯，能够抑制NF-κB，MAPK，PI3K/Akt 和β-catenin 信号传导。它可广泛用于癌症方面的研究。
TN7060	Methyl oleanonate	PPAR	DNA Damage/DNA Repair; Metabolism
	Methyl oleanonate 是从柃木中分离得到的一种三萜类天然产物，是齐墩果酸衍生物，是一种PPARγ激动剂，具有抗癌作用。
TN1712	Gossypin	NF-κB; S6 Kinase	MAPK; NF-κB; PI3K/Akt/mTOR signaling
	Gossypin 是一种从Hibiscus vitifolius 中分离得到的黄酮，能够抑制NF-κB 和 NF-κB 的调节基因表达。在小鼠原代骨髓细胞和 RAW264.7 细胞中，它也可抑制 RANKL 诱导的破骨细胞形成。它具有抗氧化、抗炎、抗癌、抗衰老、抗糖尿病和保护肝脏的活性。
T11685	Isolongifolene 异长叶烯,(-)-Isolongifolene	Apoptosis; Others	Apoptosis; Others
	Isolongifolene ((-)-Isolongifolene) 是一种从调料九里香中分离的三环倍半萜烯，具有抗氧化，抗炎，抗癌和神经保护的特性。它通过调节 PI3K/AKT/GSK-3β 信号通路来减轻鱼藤酮诱导的氧化应激，线粒体功能障碍和细胞凋亡。
T7544	Fucoidan 岩藻多糖	Others	Others
	Fucoidan 是一种 α-淀粉酶和 α-葡萄糖苷酶的有效抑制剂，是一种生物特性多糖。它具有抗凝血，抗肿瘤，抗氧化和抗脂肪特性。
T7052	Gnetol	Tyrosinase; COX; HDAC; AChR	Chromatin/Epigenetic; DNA Damage/DNA Repair; Immunology/Inflammation; Neuroscience; Proteases/Proteasome
	Gnetol 是从买麻藤的根中分离出来的一种酚类。它是酪氨酸酶抑制剂，对鼠酪氨酸酶的 IC50为 4.5 μM，可抑制黑色素的生物合成。它有效抑制 COX-1和 HDAC，具有抗氧化、抗增殖、抗癌和保肝活性，还具有浓度依赖性的 α-淀粉酶、α-葡萄糖苷酶和脂肪形成活性。
T5613	Squalane 角鲨烷,Dodecahydrosqualene,Perhydrosqualene	Others	Others
	Squalane 是某些鱼油 (尤其是鲨鱼肝油) 和某些植物油中存在的脂质。它具有抗癌，抗氧化作用，可用作皮肤保湿和润肤剂。
T2853	Curcumol 莪术醇,(-)-Curcumol,姜黄醇	Apoptosis; JAK	Angiogenesis; Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
	Curcumol ((-)-Curcumol) 是一种倍半萜，具有抗癌，抗微生物，抗真菌，抗病毒和抗炎活性。它通过靶向关键信号通路，在许多癌细胞中有效地诱导凋亡。
T1134	Clofoctol 叔辛酚氯,氯福克酚	Antibacterial; Antibiotic	Microbiology/Virology
	Clofoctol 是一种抗生素,，可研究革兰氏阳性菌感染。它仅对革兰氏阳性菌起作用, 可渗透入人类肺组织。
T3332	Isosteviol 异甜菊醇,(-)-Isosteviol	IL Receptor; Potassium Channel; TNF; NF-κB; Reactive Oxygen Species; COX; Topoisomerase	Apoptosis; DNA Damage/DNA Repair; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience; NF-κB
	Isosteviol ((-)-Isosteviol) 是一种常见的天然甜味剂，属于四环二萜糖苷，是甜菊糖苷通过酸催化水解产生的。它抑制 DNA 聚合酶和 DNA 拓扑异构酶，具有抗菌、抗癌和抗结核作用。
T2731	Usnic Acid Usniacin,松萝酸,地衣酸	Antibacterial; Autophagy	Autophagy; Microbiology/Virology
	Usnic Acid (Usniacin) 是地衣次生代谢产物，具有独特的二苯并呋喃骨架。它是一种抗菌剂、抗肿瘤剂和酶抑制剂。
T9715	Aplidine	SARS-CoV; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Aplidine 是有效的eEF1A2(KD=80 nM) 靶向的抗癌药物。Aplidine 具有抗病毒活性，抑制SARS-CoV-2的 IC90为 0.88 nM。Aplidine 在多发性骨髓瘤，晚期癌症及 COVID-19 领域有研究的价值。
TN1727	Helichrysetin 4,2',4'-三羟基-6'-甲氧基查耳酮,蜡菊亭	Apoptosis; HIV Protease	Apoptosis; Microbiology/Virology; Proteases/Proteasome
	Helichrysetin 是从豆蔻果实中分离出的一种天然产物，是一种 DNA 结合抑制剂，可抑制原位导管癌DCIS 的形成。它抑制细胞生长，可诱导 A549 细胞凋亡。
TN1990	Norathyriol 芒果苷元	Akt; DNA/RNA Synthesis; AMPK; PPAR	Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; Metabolism; PI3K/Akt/mTOR signaling
	Norathyriol 是来自芒果的芒果苷代谢物，具有抗氧化、抗癌、抗菌和抗炎活性。它以非竞争性方式抑制 α-葡萄糖苷酶，IC50为 3.12 μM。它还抑制PPARα、PPARβ和PPARγ，IC50分别为 92.8、102.4 和 153.5 µM。
TN7059	Deoxylimonin NSC 314317,脱氧柠檬苦素,desoxylimonin	Others	Others
	Deoxylimonin (NSC 314317) 是一种分离自葡萄柚籽中的三萜化合物。它是一种母体衍生物，其抗癌、缓解疼痛和抗炎活性比母体化合物强。
T3921	Punicalagin 安石榴甙,安石榴苷	SARS-CoV; HBV	Microbiology/Virology
	Punicalagin 是一种在石榴中发现的主要鞣花单宁，是可逆且非竞争性的 3CLpro 抑制剂。Punicalagin 具有抗氧化、抗炎和抗肿瘤活性。
T6995	Ochromycinone STA 21,STA21,STA-21	Antibacterial; STAT	JAK/STAT signaling; Microbiology/Virology; Stem Cells
	Ochromycinone (STA 21) 是一种天然抗生素，也是一种 STAT3抑制剂。它可抑制 STAT3DNA 结合活性，STAT3二聚化。它具有抗癌和抗菌活性。
T7730	Aminopterin APGA,氨基蝶呤,4-Aminofolic acid	Antifolate	Cell Cycle/Checkpoint
	Aminopterin (4-Aminofolic acid) 是叶酸的 4-氨基衍生物，是叶酸拮抗剂，具有抗癌和免疫抑制活性，用于研究儿童白血病。它催化叶酸还原为四氢叶酸，竞争性抑制二氢叶酸还原酶，Ki 值为 3.7 pM。
T5S0055	Chelidonine Helidonine,Khelidonin,白屈菜碱,Stylophorin	Apoptosis; Others; Influenza Virus	Apoptosis; Microbiology/Virology; Others
	Chelidonine (Stylophorin) 是白屈菜中的一种异喹啉生物碱，有抗肿瘤和抗病毒作用。它可导致细胞周期 G2/M 停滞，诱导 caspase 依赖和非依赖性的细胞凋亡。
T2800	L-Theanine L-茶氨酸,左旋茶氨酸	Apoptosis; Others	Apoptosis; Others
	L-Theanine 是一种存在于绿茶叶片中的非蛋白氨基酸物质，能阻断大脑中谷氨酸与谷氨酸受体结合，具有神经保护和抗氧化活性。它通过口服能抑制皮层神经元兴奋从而产生抗应激作用。
T3912	Saikosaponin B1 柴胡皂苷B1,柴胡皂苷 B1	Others	Others
	Saikosaponin B1 是柴胡的生物活性成分，具有抗癌作用。它能够靶向SMO 抑制 Hedgehog 通路，显著抑制髓母细胞瘤模型中的肿瘤生长。
T6169	Indirubin Indigopurpurin,Indigo red,NSC 105327,Couroupitine B,靛玉红	Apoptosis; Raf; GSK-3; CDK	Apoptosis; Cell Cycle/Checkpoint; MAPK; PI3K/Akt/mTOR signaling; Stem Cells
	Indirubin (Couroupitine B) 是一种具有抗炎症和抗癌活性的天然产物。
T0610	Piceatannol 白皮杉醇,trans-Piceatannol,Astringenin	Apoptosis; Serine/threonin kinase; PKA; Syk; PKC; Autophagy	Angiogenesis; Apoptosis; Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism; Tyrosine Kinase/Adaptors
	Piceatannol (Astringenin) 是一种Syk 抑制剂，可降低由 TNF 诱导的 iNOS 表达，可研究急性肺损伤。它是存在于各种水果和蔬菜中天然存在的多酚二苯乙烯，可诱导细胞自噬和凋亡，具有抗癌和抗炎特性。
TN1195	17-Hydroxy sprengerinin C 17-羟基麦冬皂苷C	BCL; Others; Caspase	Apoptosis; Others; Proteases/Proteasome
	17-Hydroxy sprengerinin C 是从黄精的根茎中分离得到的一种糖苷化合物，具有更强的抗癌活性。17-Hydroxy sprengerinin C 降低 Blc-2 和 pro-caspase3 的表达并增加 Bax 的产生。
T6431	Levoleucovorin Calcium 左亚叶酸钙,Calcium Levofolinate,CL307782	Others; Antifolate	Cell Cycle/Checkpoint; Others
	Levoleucovorin Calcium (CL307782) 是一种亚叶酸的钙盐，在癌症化疗中用作辅助剂。
T2230	Paeoniflorin 芍药苷,Peoniflorin	HSP; COX	Cytoskeletal Signaling; Immunology/Inflammation; Metabolism; Neuroscience
	Paeoniflorin (Peoniflorin) 是从芍药根中提取的一种蒎烷单萜糖苷，具有抗癌作用、抗氧化应激、抗血小板聚集、血管扩张、降低血液粘度和抗炎活性等多种生物活性。它是一种热休克蛋白诱导剂，通过自噬途径保护 PC12 细胞免受 MPP+和酸性损伤。
T4S0094	Hydroxygenkwanin 羟基芫花素,Luteolin 7-methylether,7-O-Methylluteolin	Antioxidant	oxidation-reduction
	Hydroxygenkwanin (Luteolin 7-methylether) 是一种丁香达芙妮的主要成分，是一种天然的类黄酮化合物。它具有抗氧化，抗神经胶质瘤能力和抗癌作用。
T1011	Itraconazole 伊曲康唑,R51211	P450; Hedgehog/Smoothened; Antibiotic; Autophagy; Antifungal	Autophagy; GPCR/G Protein; Metabolism; Microbiology/Virology; Stem Cells
	Itraconazole (R51211) 属于三唑类天然产物，是一种抗真菌剂，具有口服活性。Itraconazole 是一种 Hedgehog 信号通路拮抗剂，一种 oxysterol-binding protein (OSBP) 抑制剂，也是一种细胞色素 P-450 依赖性酶的抑制剂。
T1611	Isotretinoin 13-cis-Retinoic acid,异维A酸	Retinoid Receptor; Endogenous Metabolite; Autophagy	Autophagy; Metabolism
	Isotretinoin (13-cis-Retinoic acid) 是一种天然存在的维甲酸，具有潜在的抗肿瘤活性。它结合并激活核视黄酸受体 (RAR)，活化的 RARs 作为促进细胞分化和凋亡的转录因子。它是一种类维生素A 和维生素A 衍生物，用于治疗严重的痤疮和某些形式的皮肤、头颈癌。
T2763	Panaxadiol 人参二醇,20(R)-Panaxadiol	Others; HIF/HIF Prolyl-Hydroxylase	Chromatin/Epigenetic; Metabolism; Others
	Panaxadiol (20(R)-Panaxadiol) 是从人参根中获得，具有神经保护和抗肿瘤作用，能够抑制程序性细胞死亡配体-1(PD-L1)的表达和肿瘤增殖。
T7786	Tryptanthrin	DNA gyrase	DNA Damage/DNA Repair
	Tryptanthrin 是一种口服具有活性的细胞内Leukotriene (LT) biosynthesis 抑制剂。它能够降低大鼠胸膜炎模型中的 LTB4 水平，并抑制人全血中Leukotriene 的形成 (IC50= 10 µM)。
T2S0961	Chalcone benzylideneacetophenone,phenyl styryl ketone,Cinnamophenone,benzalacetophenone,β-phenylacrylophenone,查耳酮	EGFR; Antibacterial	Angiogenesis; JAK/STAT signaling; Microbiology/Virology; Tyrosine Kinase/Adaptors
	Chalcone (Cinnamophenone) 是从甘草中分离得到的一种芳香酮，可合成查耳酮衍生物。它具有多种生物和药理的活性，如抗炎、抗菌、抗癌、抗氧化、抗寄生虫等活性。
T4S21320	ISOGINKGETIN 异银杏素,4',4'''-Dimethylamentoflavone,异银杏双黄酮	MMP; Others	Others; Proteases/Proteasome
	ISOGINKGETIN (4',4'''-Dimethylamentoflavone) 是一种MMP9抑制剂，也是一种Pre-mRNA Splicing 抑制剂。
T5668	Triacetylresveratrol 乙酰化白藜芦醇,三乙酰基白藜芦醇,Acetyl-trans-resveratrol	BCL; NF-κB; STAT	Apoptosis; JAK/STAT signaling; NF-κB; Stem Cells
	Triacetylresveratrol (Acetyl-trans-resveratrol) 是 Resveratrol 的乙酰化类似物，可降低 STAT3和 NF-κB 磷酸化，具有抗癌作用。
T2902	Costunolide Costus lactone,NSC 106404,Costunolid,(+)-Costunolide,木香烃内酯	Apoptosis; Endogenous Metabolite; Telomerase	Apoptosis; DNA Damage/DNA Repair; Metabolism
	Costunolide (Costus lactone) 是一种天然的倍半萜内酯，具有抗氧化、抗炎、抗过敏、骨重塑、神经保护、促进毛发生长、抗癌和抗糖尿病的特性，可诱导乳腺癌细胞周期阻滞和凋亡。
T0687	Simvastatin 辛伐他汀,MK-0733,MK 733	Apoptosis; Mitophagy; Ferroptosis; HMG-CoA Reductase; Autophagy	Apoptosis; Autophagy; Metabolism
	Simvastatin (MK 733) 是一种 HMG-CoA 还原酶抑制剂 (Ki=0.2 nM)，具有口服活性。Simvastatin 具有降血脂活性，可以抑制肝脏产生胆固醇，还可以用于预防心血管疾病。
T4036	Solasodine Solancarpidine,Purapuridine,澳洲茄铵,Solasodin	Apoptosis; Others; E1/E2/E3 Enzyme; Antifungal	Apoptosis; Microbiology/Virology; Others; Ubiquitination
	Solasodine (Purapuridine) 是存在于茄科植物中的一种类固醇生物碱。它具有神经保护、降压、抗真菌、抗癌、抗动脉粥样硬化、抗雄激素和抗炎活性。
TN6864	Prosaikogenin F 前柴胡皂苷F	Others	Others
	Prosaikogenin F ((2R,3R,4S,5R,6R)-2-{[(1S,2R,4S,5R,8R,9S,10R,13S,14R,17S,18R)-2-hydroxy-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,1?.0?,1?.0?,1?.0?,13]tetracos-15-en-10-yl]oxy}-6-methyloxane-3,4,5-triol) 是一种单糖苷，具有溶血和抗癌特性。
T3604	Sodium dichloroacetate Sodium Dichloroacetate,DCA,bichloroacetic acid,二氯乙酸钠,Sodium dichloroacetate (DCA),二氯醋酸酯	Apoptosis; Dehydrogenase; Reactive Oxygen Species; PDK	Apoptosis; Immunology/Inflammation; Metabolism; NF-κB; PI3K/Akt/mTOR signaling
	Sodium dichloroacetate (DCA) 是一种肿瘤细胞线粒体中的代谢调节剂，一种丙酮酸脱氢酶激酶 (PDK) 抑制剂。Sodium dichloroacetate 具有抗肿瘤活性，可以降低肿瘤微环境中的乳酸，增加活性氧的产生并促进肿瘤细胞凋亡。
T2755	Rhoifolin 野漆树苷,Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside	Others; p38 MAPK; NF-κB; transporter; IGF-1R; Autophagy	Autophagy; MAPK; Metabolism; NF-κB; Others; Tyrosine Kinase/Adaptors
	Rhoifolin (Apigenin 7-O-neohesperidoside) 是从琯溪蜜柚叶子分离的一种黄酮糖苷。它通过 RANKL 诱导的NF-κB 和MAPK 途径改善钛颗粒刺激的骨溶解并减少破骨细胞生成。它通过增强脂联素分泌，胰岛素受体-β的酪氨酸磷酸化和GLUT4易位有助于治疗糖尿病并发症。
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天然产物

Anticancer agent 149

Cat.No: T83089

Anticancer agent 96

Cat.No: T83073

Anticancer agent 160

Cat.No: T83086

Target: Others

Anticancer agent 156

Cat.No: T83088

Cat.No: TN1873

Target: Others, Antioxidant

Cat.No: T9144

Target: Others

Cat.No: T21065

Target: Others

Cat.No: T10668

Target: Reactive Oxygen Species, ROS, Antibacterial, Antifungal

Cat.No: TN6771

Target: Others

Cat.No: TN6739

Synonym: 6-Methoxyldihydrochelerythrine

Target: IL Receptor, STAT

Deoxyelephantopin

Cat.No: TN1079

Target: NF-κB

Methyl oleanonate

Cat.No: TN7060

Target: PPAR

Cat.No: TN1712

Target: NF-κB, S6 Kinase

Cat.No: T11685

Synonym: 异长叶烯,(-)-Isolongifolene

Target: Apoptosis, Others

Cat.No: T7544

Synonym: 岩藻多糖

Target: Others

Cat.No: T7052

Target: Tyrosinase, COX, HDAC, AChR

Cat.No: T5613

Synonym: 角鲨烷,Dodecahydrosqualene,Perhydrosqualene

Target: Others

Cat.No: T2853

Synonym: 莪术醇,(-)-Curcumol,姜黄醇

Target: Apoptosis, JAK

Cat.No: T1134

Synonym: 叔辛酚氯,氯福克酚

Target: Antibacterial, Antibiotic

Cat.No: T3332

Synonym: 异甜菊醇,(-)-Isosteviol

Target: IL Receptor, Potassium Channel, TNF, NF-κB, Reactive Oxygen Species, COX, Topoisomerase

Cat.No: T2731

Synonym: Usniacin,松萝酸,地衣酸

Target: Antibacterial, Autophagy

Cat.No: T9715

Target: SARS-CoV, DNA/RNA Synthesis

Cat.No: TN1727

Synonym: 4,2',4'-三羟基-6'-甲氧基查耳酮,蜡菊亭

Target: Apoptosis, HIV Protease

Cat.No: TN1990

Synonym: 芒果苷元

Target: Akt, DNA/RNA Synthesis, AMPK, PPAR

Cat.No: TN7059

Synonym: NSC 314317,脱氧柠檬苦素,desoxylimonin

Target: Others

Cat.No: T3921

Synonym: 安石榴甙,安石榴苷

Target: SARS-CoV, HBV

Cat.No: T6995

Synonym: STA 21,STA21,STA-21

Target: Antibacterial, STAT

Cat.No: T7730

Synonym: APGA,氨基蝶呤,4-Aminofolic acid

Target: Antifolate

Cat.No: T5S0055

Synonym: Helidonine,Khelidonin,白屈菜碱,Stylophorin

Target: Apoptosis, Others, Influenza Virus

Cat.No: T2800

Synonym: L-茶氨酸,左旋茶氨酸

Target: Apoptosis, Others

Saikosaponin B1

Cat.No: T3912

Synonym: 柴胡皂苷B1,柴胡皂苷 B1

Target: Others

Cat.No: T6169

Synonym: Indigopurpurin,Indigo red,NSC 105327,Couroupitine B,靛玉红

Target: Apoptosis, Raf, GSK-3, CDK

Cat.No: T0610

Synonym: 白皮杉醇,trans-Piceatannol,Astringenin

Target: Apoptosis, Serine/threonin kinase, PKA, Syk, PKC, Autophagy

17-Hydroxy sprengerinin C

Cat.No: TN1195

Synonym: 17-羟基麦冬皂苷C

Target: BCL, Others, Caspase

Levoleucovorin Calcium

Cat.No: T6431

Synonym: 左亚叶酸钙,Calcium Levofolinate,CL307782

Target: Others, Antifolate

Cat.No: T2230

Synonym: 芍药苷,Peoniflorin

Target: HSP, COX

Hydroxygenkwanin

Cat.No: T4S0094

Synonym: 羟基芫花素,Luteolin 7-methylether,7-O-Methylluteolin

Target: Antioxidant

Cat.No: T1011

Synonym: 伊曲康唑,R51211

Target: P450, Hedgehog/Smoothened, Antibiotic, Autophagy, Antifungal

Cat.No: T1611

Synonym: 13-cis-Retinoic acid,异维A酸

Target: Retinoid Receptor, Endogenous Metabolite, Autophagy

Cat.No: T2763

Synonym: 人参二醇,20(R)-Panaxadiol

Target: Others, HIF/HIF Prolyl-Hydroxylase

Cat.No: T7786

Target: DNA gyrase

Cat.No: T2S0961

Synonym: benzylideneacetophenone,phenyl styryl ketone,Cinnamophenone,benzalacetophenone,β-phenylacrylophenone,查耳酮

Target: EGFR, Antibacterial

Cat.No: T4S21320

Synonym: 异银杏素,4',4'''-Dimethylamentoflavone,异银杏双黄酮

Target: MMP, Others

Triacetylresveratrol

Cat.No: T5668

Synonym: 乙酰化白藜芦醇,三乙酰基白藜芦醇,Acetyl-trans-resveratrol

Target: BCL, NF-κB, STAT

Cat.No: T2902

Synonym: Costus lactone,NSC 106404,Costunolid,(+)-Costunolide,木香烃内酯

Target: Apoptosis, Endogenous Metabolite, Telomerase

Cat.No: T0687

Synonym: 辛伐他汀,MK-0733,MK 733

Target: Apoptosis, Mitophagy, Ferroptosis, HMG-CoA Reductase, Autophagy

Cat.No: T4036

Synonym: Solancarpidine,Purapuridine,澳洲茄铵,Solasodin

Target: Apoptosis, Others, E1/E2/E3 Enzyme, Antifungal

Prosaikogenin F

Cat.No: TN6864

Synonym: 前柴胡皂苷F

Target: Others

Sodium dichloroacetate

Cat.No: T3604

Synonym: Sodium Dichloroacetate,DCA,bichloroacetic acid,二氯乙酸钠,Sodium dichloroacetate (DCA),二氯醋酸酯

Target: Apoptosis, Dehydrogenase, Reactive Oxygen Species, PDK

Cat.No: T2755

Synonym: 野漆树苷,Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside

Target: Others, p38 MAPK, NF-κB, transporter, IGF-1R, Autophagy

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-05033	5T4/TPBG Protein, Human, Recombinant (aa 60-345, His) 5T4AG,trophoblast glycoprotein,WAIF1,M6P1,5T4	Human	HEK293 Cells
	Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. 5T4/TPBG Protein, Human, Recombinant (aa 60-345, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.1 kDa and the accession number is Q13641.
TMPY-04644	PDGFB Protein, Human, Recombinant (His) platelet-derived growth factor beta polypeptide,SSV,c-sis,SI...	Human	P. pastoris (Yeast)
	Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted...
TMPY-06191	5T4/TPBG Protein, Mouse, Recombinant (His) trophoblast glycoprotein,WAIF1,5T4,AW495680	Mouse	HEK293 Cells
	Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. 5T4/TPBG Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.2 kDa and the accession number is Q9Z0L0.
TMPY-06214	5T4/TPBG Protein, Mouse, Recombinant (hFc) trophoblast glycoprotein,AW495680,5T4,WAIF1	Mouse	HEK293 Cells
	Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. 5T4/TPBG Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.5 kDa and the accession number is Q9Z0L0.
TMPK-01310	Syndecan-1 Protein, Rabbit, Recombinant (His) SDC1,SYND1,SDC,CD138,Syndecan 1	Rabbit	HEK293 Cells
	CD138 (syndecan-1, Sdc-1) is a member of the syndecan family that comprises heparan sulfate proteoglycans. CD138 is significant for cell-cell and cell-matrix interactions.CD138 plays a crucial role in carcinogenesis and is an attractive target for anticancer treatment with heparanase inhibitors and anti-CD138 antibodies for immunotherapy.
TMPY-06317	5T4/TPBG Protein, Human, Recombinant (aa 1-355, His) trophoblast glycoprotein,WAIF1,5T4AG,M6P1,5T4	Human	HEK293 Cells
	Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. 5T4/TPBG Protein, Human, Recombinant (aa 1-355, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.15 kDa and the accession number is NP_006661.1.
TMPK-00721	CX3CL1/Fractalkine Protein, Mouse, Recombinant (His & Avi), Biotinylated Neurotactin,CXC3C,ABCD-3,Fkn,Fractalkine,NTT,Cx3cl1,SCYD1,Cx...	Mouse	HEK293 Cells
	Fractalkine/CX3C chemokine ligand 1 (CX3CL1) is a chemokine involved in the anticancer function of lymphocytes-mainly NK cells, T cells and dendritic cells. Its increased levels in tumors improve the prognosis for cancer patients, although it is also associated with a poorer prognosis in some types of cancers, such as pancreatic ductal adenocarcinoma.
TMPY-05077	PDGFB Protein, Rhesus, Recombinant (His) platelet-derived growth factor β polypeptide,platelet-derive...	Rhesus	P. pastoris (Yeast)
	Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Rhesus, Recombinant (His) is expressed in yeast with His tag. The predicte...
TMPK-00060	IL-17B Protein, Mouse, Recombinant (His) IL20,interleukin 17B,interleukin 20,IL-17B,MGC138901,ZCYTO7,...	Mouse	E. coli
	IL-17A, the prototypic member of the IL-17 family, several experimental findings strongly support the role of the IL-17B/IL-17 receptor B (IL-17RB) pathway in tumorigenesis and resistance to anticancer therapies. IL-17B/IL-17RB expression patterns and biological activities in cancer and highlight issues that remain to be addressed to better characterize IL-17B and its receptor as potential targets for enhancing the effectiveness of the existing cancer therapies.
TMPY-04877	PDGFB Protein, Mouse, Recombinant (His) platelet-derived growth factor β polypeptide,血小板源生长因子,Sis,pl...	Mouse	P. pastoris (Yeast)
	Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Mouse, Recombinant (His) is expressed in yeast with His tag. The predicted...
TMPY-02395	PDGFB Protein, Cynomolgus, Recombinant (mFc) 血小板源生长因子,platelet-derived growth factor beta polypeptide,pla...	Cynomolgus	HEK293 Cells
	Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Cynomolgus, Recombinant (mFc) is expressed in HEK293 mammalian cells with ...
TMPK-00710	Claudin-4 Protein-VLP, Human, Recombinant Claudin4,CLDN4,Claudin-4,CPETR1,CPE-R,WBSCR8,CPE R	Human	HEK293 Cells
	Claudin-4 (CLDN4) is a key component of tight junctions (TJs) in epithelial cells. CLDN4 is overexpressed in many epithelial malignancies and correlates with cancer progression. Changes in CLDN4 expression have been associated with epigenetic factors (such as hypomethylation of promoter DNA), inflammation associated with infection and cytokines, and growth factor signaling. CLDN4 helps to maintain the tumor microenvironment by forming TJs and acts as a barrier to the entry of anticancer drugs in...
TMPY-05076	PDGFB Protein, Canine, Recombinant (His) platelet-derived growth factor beta polypeptide,platelet-der...	Canine	P. pastoris (Yeast)
	Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Canine, Recombinant (His) is expressed in yeast with His tag. The predicte...
TMPJ-00247	METAP1 Protein, Human, Recombinant METAP1,Methionine aminopeptidase 1,MAP 1,MetAP 1,Peptidase M...	Human	E. coli
	Methionine Aminopeptidase 1 is a member of the M24 family of metalloproteases. METAP1 plays an important role in G(2)/M phase regulation of the cell cycle and may serve as a promising target for the discovery and development of new anticancer agents. METAP1 and METAP2 have different substrate specificity due to the differences in both size and shape of the active sites. The proteolytic removal of N-terminal methionine from nascent peptides is catalyzed by a family of enzymes known as methionine...
TMPY-01865	BLMH Protein, Mouse, Recombinant (His) Bh,bleomycin hydrolase,Bmh,AI035728	Mouse	E. coli
	The papain superfamily member bleomycin hydrolase (BLMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution. The only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The papain superfamily member bleomycin hydrolase (BLMH) is a neutral cysteine protease with structural similarity to a 20S proteasome. Bleomycin (BLM), a clinically used glycopeptide antica...
TMPY-02072	HSF1 Protein, Human, Recombinant (His) HSTF1,heat shock transcription factor 1	Human	E. coli
	Heat shock factor protein 1, also known as heat shock transcription factor 1, HSF1, and HSTF1, is a cytoplasm and nucleus protein that belongs to the HSF family. HSF1 is the major transcription factor of HSPs (heat shock proteins) in response to various stresses. Wild type HSF1 (heat shock transcriptional factor 1) is normally inactive. HSF1 / HSTF1 is a DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable...

重组蛋白

5T4/TPBG Protein, Human, Recombinant (aa 60-345, His)

Cat.No: TMPY-05033

Species: Human

Expression System: HEK293 Cells

PDGFB Protein, Human, Recombinant (His)

Cat.No: TMPY-04644

Species: Human

Expression System: P. pastoris (Yeast)

5T4/TPBG Protein, Mouse, Recombinant (His)

Cat.No: TMPY-06191

Species: Mouse

Expression System: HEK293 Cells

5T4/TPBG Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-06214

Species: Mouse

Expression System: HEK293 Cells

Syndecan-1 Protein, Rabbit, Recombinant (His)

Cat.No: TMPK-01310

Species: Rabbit

Expression System: HEK293 Cells

5T4/TPBG Protein, Human, Recombinant (aa 1-355, His)

Cat.No: TMPY-06317

Species: Human

Expression System: HEK293 Cells

CX3CL1/Fractalkine Protein, Mouse, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00721

Species: Mouse

Expression System: HEK293 Cells

PDGFB Protein, Rhesus, Recombinant (His)

Cat.No: TMPY-05077

Species: Rhesus

Expression System: P. pastoris (Yeast)

IL-17B Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00060

Species: Mouse

Expression System: E. coli

PDGFB Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04877

Species: Mouse

Expression System: P. pastoris (Yeast)

PDGFB Protein, Cynomolgus, Recombinant (mFc)

Cat.No: TMPY-02395

Species: Cynomolgus

Expression System: HEK293 Cells

Claudin-4 Protein-VLP, Human, Recombinant

Cat.No: TMPK-00710

Species: Human

Expression System: HEK293 Cells

PDGFB Protein, Canine, Recombinant (His)

Cat.No: TMPY-05076

Species: Canine

Expression System: P. pastoris (Yeast)

METAP1 Protein, Human, Recombinant

Cat.No: TMPJ-00247

Species: Human

Expression System: E. coli

BLMH Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01865

Species: Mouse

Expression System: E. coli

HSF1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02072

Species: Human

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
TMID-0058	Glycocholic acid-d4
	Glycocholic acid-d4 是 Glycocholic acid 的氘代化合物。Glycocholic acid 的 CAS 号为 475-31-0。Glycocholic acid 是一种胆汁酸，具有抗肿瘤活性，能够靶向作用于耐药泵和非耐药泵通路。
TMIJ-0050	Butyricacid-d7
	Butyricacid-d7 是 Butyricacid 的氘代化合物。Butyricacid 的 CAS 号为 107-92-6。Butyric acid 是一种从许多乳制品中分离出来的脂肪酸，具有抗癌活性。它抑制组蛋白去乙酰化酶 (HDAC) 并诱导胶质瘤细胞凋亡和 G1 期细胞周期停滞。此外，它在低剂量时刺激上皮细胞增殖，在高剂量时抑制增殖。
TMIJ-0099	Minodronic acid-d4
	Minodronic acid-d4 是 Minodronic acid 的氘代化合物。Minodronic acid 的 CAS 号为 180064-38-4。Minodronic acid(YM-529) 是一种 P2X2/3 受体拮抗剂，具有抗癌活性，可直接或间接的抑制癌细胞增殖，诱导细胞凋亡。Minodronic-acid 对各种类型的癌细胞的转移具有抑制作用。Minodronic-acid 可用于研究骨质疏松。

同位素标记化合物

Glycocholic acid-d4

Cat.No: TMID-0058

Cat.No: TMIJ-0050

Minodronic acid-d4

Cat.No: TMIJ-0099

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