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GlutaminaseC-IN-2(compound 11)为GAC变构抑制剂,IC50值为10.64 nM。该化合物通过干扰谷氨酰胺代谢,调控细胞代谢产物,进而提高ROS水平,并展现出抗癌活性。
GlutaminaseC-IN-2(compound 11)为GAC变构抑制剂,IC50值为10.64 nM。该化合物通过干扰谷氨酰胺代谢,调控细胞代谢产物,进而提高ROS水平,并展现出抗癌活性。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | 询价 | 期货 | |
50 mg | 询价 | 期货 |
产品描述 | Glutaminase C-IN-2 (compound 11), an allosteric inhibitor of glutaminase C (GAC), exhibits potent inhibitory activity with an IC50 of 10.64 nM. By disrupting glutamine metabolism, this compound modulates cellular metabolites and elevates reactive oxygen species (ROS), exerting anticancer effects [1]. |
分子量 | 473.55 |
分子式 | C24H23N7O2S |
存储 | Shipping with blue ice. |
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