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Eeyarestatin I 是具有抑制内质网相关蛋白质降解和蛋白易位的抑制剂。Eeyarestatin I 与p97去泛素过程相关,抑制atx3的去泛素化。Eeyarestatin I 通过诱导蛋白质使细胞死亡,具有抗癌作用。
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Eeyarestatin I 是具有抑制内质网相关蛋白质降解和蛋白易位的抑制剂。Eeyarestatin I 与p97去泛素过程相关,抑制atx3的去泛素化。Eeyarestatin I 通过诱导蛋白质使细胞死亡,具有抗癌作用。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 425 | 现货 | |
5 mg | ¥ 987 | 现货 | |
10 mg | ¥ 1,490 | 现货 | |
25 mg | ¥ 2,490 | 现货 | |
50 mg | ¥ 3,730 | 现货 |
产品描述 | Eeyarestatin I is an inhibitor that inhibits the degradation and translocation of ER-associated proteins. Eeyarestatin I is associated with the p97 deubiquitination process and inhibits atx3 deubiquitination. Eeyarestatin I has anticancer effects by inducing proteins that cause cell death. |
靶点活性 | UbG76V-GFP:3.7 μM, p97:> 30 μM |
分子量 | 630.44 |
分子式 | C27H25Cl2N7O7 |
CAS No. | 412960-54-4 |
Smiles | CC1(C)C(N(O)C(=O)Nc2ccc(Cl)cc2)N(C(=O)N1CC(=O)N\N=C\C=C\c1ccc(o1)[N+]([O-])=O)c1ccc(Cl)cc1 |
密度 | 1.49 g/cm3 (Predicted) |
存储 | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
溶解度信息 | DMSO: 22.5 mg/mL (35.7 mM), Sonication is recommended. | |||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||
DMSO
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