|
TMPY-00264
|
NPC2 Protein, Rat, Recombinant (His)
Niemann-Pick disease, type C2
|
Rat
|
HEK293 Cells
|
|
NPC2 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.9 kDa and the accession number is Q8CHN5. |
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TMPY-00131
|
Niemann Pick C1/NPC1 Protein, Human, Recombinant (His & FLAG)
NPC,Niemann-Pick disease, type C1
|
Human
|
HEK293 Cells
|
|
Niemann-Pick C1 (NPC1), a host receptor involved in the envelope glycoprotein (GP)-mediated entry of filoviruses into cells, is believed to be a major determinant of cell susceptibility to filovirus infection. Niemann-Pick C1 (NPC1), a membrane protein of lysosomes, is required for the export of cholesterol derived from receptor-mediated endocytosis of LDL. The NPC1 protein is a multipass transmembrane protein whose deficiency causes the autosomal recessive lipid storage disorder Niemann-Pick ty... |
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TMPY-01114
|
NPC2 Protein, Human, Recombinant (His)
HE1,Niemann-Pick disease, type C2,EDDM1
|
Human
|
HEK293 Cells
|
|
NPC2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16 kDa and the accession number is P61916-1. |
|
TMPY-04990
|
NPC2 Protein, Mouse, Recombinant (His)
2700012J19Rik,HE1,AA408070,AU045843,Niemann-Pick disease...
|
Mouse
|
HEK293 Cells
|
|
NPC2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.9 kDa and the accession number is Q9Z0J0. |
|
TMPH-01887
|
Polycystin-1 Protein, Human, Recombinant (His)
Autosomal dominant polycystic kidney disease 1 prot...
|
Human
|
E. coli
|
|
Polycystin-1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 69.3 kDa and the accession number is P98161. |
|
TMPH-03059
|
Newcastle disease virus (NDV) (strain Her/33) Hemagglutinin-neuraminidase Protein (His)
HN,Hemagglutinin-neuraminidase
|
NDV
|
E. coli
|
|
Mediates the viral entry into the host cell together with fusion/F protein. Attaches the virus to sialic acid-containing cell receptors and thereby initiates infection. Binding of HN protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion.; Neuraminidase activity ensures the efficient spread of the virus by dissociating the mature virions from the neuraminic acid containing glycoproteins. Newcastle disease virus (NDV) (strain Her/... |
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TMPH-01782
|
Norrin Protein, Human, Recombinant (GST & His & Myc)
Norrie disease protein,NDP,X-linked exudative vitre...
|
Human
|
E. coli
|
|
Norrin Protein, Human, Recombinant (GST & His & Myc) is expressed in E. coli expression system with N-10xHis-GST and C-Myc tag. The predicted molecular weight is 47.6 kDa and the accession number is Q00604. |
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TMPH-01262
|
PRKN Protein, Human, Recombinant (His & Myc)
Parkinson juvenile disease protein 2,E3 ubiquitin-p...
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Human
|
Baculovirus Insect Cells
|
|
PRKN Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 55.6 kDa and the accession number is O60260. |
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TMPH-01263
|
PRKN Protein, Human, Recombinant (His & SUMO)
PRKN,Parkin RBR E3 ubiquitin-protein ligase,E3 ubiquitin-pro...
|
Human
|
E. coli
|
|
Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Substrates include SYT11 and VDAC1. Other substrates are BCL2, CCNE1, GPR37, RHOT1/MIRO1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, MIRO1 and AIMP2. Mediates monoubiquitination as well as 'Lys-6', 'Lys-11', 'Lys-48'-linked and 'Lys-63'-linked polyubiquitination of substrates depending on the context. Participates in the removal and/or det... |
|
TMPH-01916
|
PIP Protein, Human, Recombinant (His)
gp17,Secretory actin-binding protein,Gross cystic diseas...
|
Human
|
E. coli
|
|
PIP Protein, Human, Recombinant (His) is expressed in E. coli. |
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TMPJ-00848
|
NCF1 Protein, Human, Recombinant (His)
Nox-organizing protein 2/SH3 and PX domain-containing protei...
|
Human
|
E. coli
|
|
Neutrophil cytosol factor 1( NCF1) is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is characterized as a multicomponent enzyme which is activated to produce superoxide anion. NCF2, NCF1, and a membrane bound cytochrome b558 are required for the activation of the latent NADPH oxidase. The human NCF1 gene encodes a 390 amino acids protein without a signal peptide. The NCF1 gene interacts with other subunits of nicotinamide adenine dinucleotide phosphate-oxidase (NADPH) and ... |
|
TMPY-02585
|
Acid sphingomyelinase/SMPD1 Protein, Mouse, Recombinant (His)
aSMase,ASM,Zn-SMase,A-SMase,sphingomyelin phosphodiesterase ...
|
Mouse
|
Baculovirus Insect Cells
|
|
Sphingomyelin phosphodiesterase 1 (SMPD1) , also known as ASM ( acid sphingomyelinase ), is a member of the acid sphingomyelinase family of enzymes. Three isoforms have been identified, isoform 1 is 631 amino acids (aa) in length as the pro form, while Isoform 2 and isoform 3 have lost catalytic activity. The active SMPD1 isoform 1 contains one saposin B-type domain that likely interacts with sphingomyelin, and a catalytic region. Human SMPD1 is 86% aa identical to mouse SMPD1. SMPD1 is a monome... |
|
TMPY-01355
|
Transglutaminase 2/TGM2 Protein, Human, Recombinant (His)
G-α-h,HEL-S-45,TGC,transglutaminase 2,TG2,GNAH,G-ALPHA-h
|
Human
|
Baculovirus Insect Cells
|
|
Protein-glutamine gamma-glutamyltransferase 2, also known as Tissue transglutaminase, Transglutaminase C, Transglutaminase-2, and TGM2, is a member of the transglutaminase superfamily. TGM2 plays a role in cell growth and survival through the anti-apoptosis signaling pathway. It is a calcium-dependent acyltransferase that also undergoes a GTP-binding/GTPase cycle even though it lacks any obvious sequence similarity with canonical GTP-binding (G) proteins. TGM2 is a multi-functional protein which... |
|
TMPY-04989
|
Galectin-9 Protein, Human, Recombinant (hFc)
LGALS9A,lectin, galactoside-binding, soluble, 9,HUAT
|
Human
|
HEK293 Cells
|
|
LGALS9 (Galectin 9) is a Protein Coding gene. 6 alternatively spliced human isoforms have been reported. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or i... |
|
TMPJ-01468
|
pro-Beta NGF Protein, Human, Recombinant
β-NGF,NGF,NGFB,Beta-NGF,Beta-Nerve Growth Factor,pro-Beta NG...
|
Human
|
E. coli
|
|
The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration. |
|
TMPY-04722
|
DcR1/TRAILR3 Protein, Human, Recombinant (His)
TRAILR3,TRID,DCR1,TRAIL-R3,CD263,DCR1-TNFR,tumor necrosis fa...
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Human
|
HEK293 Cells
|
|
TNFRSF10C CNV in patients with CRC is associated with distant metastatic disease. A high frequency of CGI methylation in the TNFRSF10C promoter results in inactivation of the gene and enhancement of tumor growth in most PC cell lines (except CFPAC-1). Inactivation of TNFRSF10C by CpG island (CGI) hypermethylation can play an important role in PC progression and be potentially useful as a diagnostic marker and a new therapeutic approach for PC. |
|
TMPK-00047
|
IFN gamma Protein, Human, Recombinant (His & Avi)
IFN gamma,interferon,Interferon-γ,γ,IFI,干扰素,Interferon-gamma...
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Human
|
HEK293 Cells
|
|
Interferon-gamma (IFN gamma) is a cytokine that plays physiologically important roles in promoting innate and adaptive immune responses. The absence of IFN gamma production or cellular responsiveness in humans and experimental animals significantly predisposes the host to microbial infection, a result that validates the physiologic importance of this cytokine in preventing infectious disease. IFN gamma Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi ... |
|
TMPK-00639
|
Alkaline Phosphatase (Germ type) /ALPG Protein, Rat, Recombinant (His)
GCAP,ALP-1,Alkaline Phosphatase,ALPPL2,PLAP-like,ALPPL,ALPG,...
|
Rat
|
HEK293 Cells
|
|
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline Phosphatase (Germ type) /ALPG Protein, Rat, Recombinant (His) is expressed in HEK293... |
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TMPK-01246
|
GDF-15 Protein, Mouse, Recombinant (His)
MIC1,Placental TGF-beta,Placental TGF-β,PTGF-beta,PTGFBPTGF-...
|
Mouse
|
E. coli
|
|
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Mouse, Rec... |
|
TMPY-01075
|
Von Willebrand Factor/vWF Protein, Human, Recombinant (His)
von Willebrand factor,VWD,F8VWF
|
Human
|
CHO Cells
|
|
Von Willebrand Factor (VWF) is a multimeric glycoprotein involved in hemostasis in blood, binds receptors on the surface of platelets and in connective tissue, thereby mediating the adhesion of platelets to sites of vascular injury. From studies it appears that VWF protein uncoils under these circumstances, decelerating passing platelets. VWF protein is deficient or defective in von Willebrand disease (VWD) and is involved in a large number of other diseases, including thrombosis, thrombotic thr... |
|
TMPY-00545
|
Dermcidin Protein, Human, Recombinant (hFc)
AIDD,PIF,HCAP,dermcidin,DCD-1,DSEP
|
Human
|
HEK293 Cells
|
|
Hepatocellular carcinoma (HCC) is a major contributor to cancer-related deaths due to its often late stage diagnosis, and dermcidin (DCD) may have the potential to be used as a serum biomarker for HCC for more timely diagnoses. Human dermcidin (DCD) is an antimicrobial peptide secreted constitutively by sweat glands. And the role of DCD in ischemic heart disease has drawn increasing attention in particular its relationship with insulin secretion and glycemic control, nitric oxide (NO) synthesis ... |
|
TMPY-04310
|
Apolipoprotein A-IV/APOA4 Protein, Human, Recombinant (His)
apolipoprotein A-IV
|
Human
|
HEK293 Cells
|
|
Apolipoprotein is genetically associated with the risk of Alzheimer's disease (AD). The APOA1, APOC3, and APOA4 genes are closely linked and located on human chromosome 11. There was a decreased trend for levels of APOA1, APOC3, and APOA4 in AD patients. CONCLUSION: Low levels of APOA1, APOC3, and APOA4 are associated with risk of AD. APOA1, APOC3, and APOA4 should be developed as combined drugs for the therapy of AD. SNP(single nucleotide polymorphisms)in APOA1and APOA4 genes influences atherog... |
|
TMPK-00369
|
HGF Protein, Human, Recombinant (hFc)
HGF,F-TCF,HGFB,SF,F-TCFB,肝细胞生长因子,DFNB39,Hepatopoietin-A,HPTA
|
Human
|
HEK293 Cells
|
|
Hepatocyte growth factor (HGF) is an important component of the pathophysiology of IR, with increased levels in most common IR conditions, including obesity. HGF has a role in the metabolic flux of glucose in different insulin sensitive cell types; plays a key role in β-cell homeostasis; and is capable of modulating the inflammatory response.HGF plays a central role in these metabolic disorders,HGF levels could be employed as a biomarker for disease status/progression, and HGF/c-Met signaling pa... |
|
TMPJ-00258
|
TGF beta 2 Protein, Human, Recombinant
Glioblastoma-derived T-cell suppressor factor,TGF-β-2,Transf...
|
Human
|
HEK293 Cells
|
|
Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. Defects in TGFB2 may be... |
|
TMPJ-00135
|
BDNF Protein, Human/Murine/Rat, Recombinant
BDNF,Abrineurin,Brain-Derived Neurotrophic Factor
|
Human,Mouse,Rat
|
E. coli
|
|
Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. ... |
|
TMPJ-00249
|
TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated
TGF-Beta-1,TGFB1,Transforming Growth Factor β-1,Latency-Asso...
|
Human
|
HEK293 Cells
|
|
Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family... |
|
TMPJ-00651
|
CD155/PVR Protein, Human, Recombinant (aa 21-343, His)
Poliovirus Receptor,PVS,Nectin-Like Protein 5,NECL-5,CD155,P...
|
Human
|
HEK293 Cells
|
|
Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains, a transmembrane segment, and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension be... |
|
TMPY-04483
|
IRAK4 Protein, Human, Recombinant (His)
IPD1,NY-REN-64,REN64,interleukin-1 receptor-associated kinas...
|
Human
|
Baculovirus Insect Cells
|
|
Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4 contains one death domain and one protein kinase domain. IRAK4 is required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. ... |
|
TMPY-03855
|
DNase I Protein, Human, Recombinant (His)
DRNI,DNL1,deoxyribonuclease I
|
Human
|
HEK293 Cells
|
|
DNase1, also known as deoxyribonuclease I and DNL1, is a member of the DNase family. DNaseI is a nuclease that cleaves DNA preferentially at phosphodiester linkages adjacent to a pyrimidine nucleotide, yielding 5'-phosphate-terminated polynucleotides with a free hydroxyl group on position 3', on average producing tetranucleotides. DNaseI binds to the cytoskeletal protein actin. It binds actin monomers with very high (sub-nanomolar) affinity and actin polymers with lower affinity. Mutations i... |
|
TMPY-04069
|
Neurotrophin 3 Protein, Human, Recombinant
NGF2,HDNF,NT-3,neurotrophin 3,NGF-2,NT3
|
Human
|
E. coli
|
|
NTF3 (Neurotrophin 3) is a Protein Coding gene. The protein encoded by this gene is a member of the neurotrophin family, that controls the survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. NTF3 is a key mediator of neuronal development during the early neurogenic period. NTF3 is a novel target gene of POU3F2 and that the POU3F2/NTF3 pathway plays a role in the process of neuronal differentiation. ... |
|
TMPY-02258
|
Kallikrein 3/KLK3 Protein, Human, Recombinant (His)
APS,KLK2A1,PSA,kallikrein related peptidase 3,Hk3
|
Human
|
HEK293 Cells
|
|
KLK3 (Kallikrein Related Peptidase 3) is a Protein Coding gene. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease that is synthesized in the epithelial cells of the prostate gland and is present in seminal plasma. KLK3, also known as Prostate Specific Antigen (PSA), kallikrein-related peptidase 3, Gamma-seminoprotein, is a secreted protein of the glandular kallikrein subfamily of serine proteases.... |
|
TMPY-00369
|
LY6D Protein, Human, Recombinant (mFc)
E48,lymphocyte antigen 6 complex, locus D,Ly-6D
|
Human
|
HEK293 Cells
|
|
LY6D (Lymphocyte Antigen 6 Family Member D) is a Protein Coding gene. It may act as a specification marker at the earliest stage specification of lymphocytes between B- and T-cell development. Marks the earliest stage of B-cell specification. The expression of LY6D is induced in MCF10A cells by X-ray irradiation. The induction of LY6D expression is triggered through a pathway regulated by ATM, CHK2, and p53. This method is a new Ab-directed proteomic strategy for the analysis of membrane protein... |
|
TMPY-00672
|
Azurocidin/CAP37 Protein, Human, Recombinant (His)
AZU,NAZC,azurocidin 1,hHBP,AZAMP,HUMAZUR,CAP37,HBP,AZU1
|
Human
|
HEK293 Cells
|
|
Azurocidin (AZU1), also known as heparin-binding protein (HBP) or cationic antimicrobial protein 37 (CAP37), is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. The Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. Azurocidin is a member of the serine protease family that includes Cathepsin G, neutrophil elastase (NE), and proteinase 3 (PR3), however, Azurocidin is n... |
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TMPY-03425
|
Tau Protein, Human, Recombinant (His)
PPND,FTDP-17,MTBT1,DDPAC,MAPTL,MTBT2,microtubule-associated ...
|
Human
|
E. coli
|
|
MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. Tau protein is a highly soluble microtubule-associated protein (MAP... |
|
TMPY-02956
|
Apolipoprotein L/APOL1 Protein, Human, Recombinant (His)
APOL1,apolipoprotein L1,APOL,FSGS4,APOL-I,APO-L
|
Human
|
Baculovirus Insect Cells
|
|
APOL1, also known as apolipoprotein L1, is a minor apoprotein component of HDL (High-density lipoprotein) or 'good cholesterol' which is synthesized in the liver and also in many other tissues, including pancreas, kidney, and brain. APOL1 belongs to the apolipoprotein L family. It may play a role in lipid exchange and transport throughout the body. It may also participate in reverse cholesterol transport from peripheral cells to the liver. Defects in APOL1 are the cause of focal segmental glomer... |
|
TMPY-03407
|
NQO1 Protein, Human, Recombinant (His)
NAD(P)H dehydrogenase, quinone 1,NMORI,DIA4,QR1,NMOR1,DTD,DH...
|
Human
|
E. coli
|
|
NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-electron reduction of quinones that results in the production of radical species. Mutations in the NQO1 gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered ex... |
|
TMPY-02115
|
R-Spondin 3/RSPO3 Protein, Human, Recombinant (aa 1-146, His)
CRISTIN1,THSD2,R-spondin 3,PWTSR
|
Human
|
HEK293 Cells
|
|
R-spondin 3 (RSPO3) is a member of the R-Spondin (RSPO) family in vertebrates that activate Wnt/beta-catenin signaling, plays a key role in these processes. The RSPO family of secreted Wnt modulators is involved in development and disease and holds therapeutic promise as stem cell growth factors. The four members have high structural homology. RSPO2 and RSPO3 are more potent than RSPO1, whereas RSPO4 is relatively inactive. All RSPO members require Wnt ligands and LRP6 for activity and amplify s... |
|
TMPY-02779
|
Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)
thyroid peroxidase,MSA,TPX,TDH2A
|
Human
|
Baculovirus Insect Cells
|
|
Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. It used to be taken as the formerly so-called `microsomal antigen` several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two i... |
|
TMPY-02078
|
HtrA2/Omi Protein, Human, Recombinant (His)
PARK13,OMI,HtrA serine peptidase 2,PRSS25
|
Human
|
E. coli
|
|
Serine protease HTRA2, also known as high-temperature requirement protein A2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI and HTRA2, is a single-pass membrane protein that belongs to the peptidase S1B family. HTRA2 contains one PDZ (DHR) domain. HTRA2 is a serine protease that shows proteolytic activity against a non-specific substrate beta-casein. It promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor... |
|
TMPJ-00071
|
EPO/Erythropoietin Protein, Human, Recombinant (His)
Erythropoietin,EPO,红细胞生长素,Epoetin
|
Human
|
HEK293 Cells
|
|
Erythropoietin (EPO) is a glycoprotein hormone that is principally known for its role in erythropoiesis, where it is responsible for stimulating proliferation and differentiation of erythroid progenitor cells. Erythropoietin is a member of the EPO/TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. The differentiation of CFU-E (Colony Forming Unit-Erythroid) cells into erythrocytes can only be accomplished in the presence of EPO. Physiological levels of EP... |
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TMPY-01061
|
FGF-10 Protein, Human, Recombinant
fibroblast growth factor 10,KGF2
|
Human
|
E. coli
|
|
Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF10 exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. FGF10 pla... |
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TMPJ-00137
|
APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)
TRDL-1,TNF- and APOL-related leukocyte expressed ligand 2,Tu...
|
Human
|
HEK293 Cells
|
|
APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. Secreted human APRIL, which consists almost entirely of a single TNF homology domain, shares 85% amino acid sequence identity with mouse and rat APRIL. Both APRIL and its close relative BAFF bind and signal through the TNF superfamily recept... |
|
TMPY-04830
|
GAS6 Protein, Mouse, Recombinant (His)
growth arrest-specific 6,Gas-6
|
Mouse
|
HEK293 Cells
|
|
The growth arrest-specific 6 gene (GAS6) is a member of the family of plasma vitamin K-dependent proteins, which are able to bind to phospholipids using an N-terminal gamma-carboxyglutamic acid domain. GAS6 is a vitamin K-dependent protein, plays a role in the survival, proliferation, migration, differentiation, adhesion, and apoptosis of cells. The growth arrest-specific 6 (GAS6) has been implicated in systemic inflammation and coagulation. Growth arrest-specific 6 (GAS6), plays a role in tumor... |
|
TMPY-02153
|
TNF beta Protein, Human, Recombinant
LT,TNF β,TNFSF1,肿瘤坏死因子,TNFB,lymphotoxin alpha,lymphotoxin α
|
Human
|
E. coli
|
|
Lymphotoxin-alpha, also known as LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA TNFSF1, and TNFB, is a secreted protein that belongs to the tumor necrosis factor family. TNF-beta/TNFSF1/Lymphotoxin alpha is highly inducible, secreted, and exists as a homotrimeric molecule. It is a cytokine that in its homotrimeric form binds to TNFRSF1A / TNFR1, TNFRSF1B / TNFBR, and TNFRSF14 / HVEM. In its heterotrimeric form with LTB, TNF-beta/TNFSF1/Lymphotoxin alpha binds to TNFRS... |
|
TMPY-00021
|
PADI4 Protein, Human, Recombinant (His)
PADI5,PAD4,PDI4,peptidyl arginine deiminase, type IV,PAD,PDI...
|
Human
|
Baculovirus Insect Cells
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Protein-arginine deiminase type-4, also known as HL-6 PAD, Peptidylarginine deiminase IV, Protein-arginine deiminase type I V and PADI4, is a cytoplasm and nucleus protein that belongs to the protein arginine deiminase family. PADI4 is expressed in CD34+stem cells in normal tissues, and many more CD34+ cells expressing PADI4 are present in tumour tissues. PADI4 post-translationally converts peptidylarginine to citrulline, a process called citrullination. Studies have demonstrated the high expres... |
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TMPY-01101
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Coagulation factor X/F10 Protein, Human, Recombinant (His)
FXA,FX,coagulation factor X,coagulation factor 10
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Human
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Baculovirus Insect Cells
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Coagulation factor X, also known as FX, F10, Eponym Stuart-Prower factor, and thrombokinase, is an enzyme of the coagulation cascade. It is one of the vitamin K-dependent serine proteases, and plays a crucial role in the coagulation cascade and blood clotting, as the first enzyme in the common pathway of thrombus formation. Factor X deficiency is one of the rarest of the inherited coagulation disorders. FX deficiency among the most severe of the rare coagulation defects, typically including hema... |
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TMPK-01063
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LRP-10 Protein, Mouse, Recombinant (His)
Lrp10,LRP-10,Lrp9
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Mouse
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HEK293 Cells
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LDL receptor-related protein (LRP) 10 was recently identified as a Parkinson's disease gene through genome-wide linkage and sequencing analysis, but its role in Parkinson's disease in various populations is still unclear. |
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TMPK-00096
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FGF-10 Protein (Primary Amine Labeling), Human, Recombinant, Biotinylated
FGF-10,KGF2
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Human
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E. coli
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Fibroblast growth factor 10 (FGF10) regulates multiple stages of structural lung morphogenesis, cellular differentiation, and the response to injury. As a driver of lung airway branching morphogenesis, FGF10 signaling defects during development lead to neonatal lung disease. Lung diseases impact patients across the lifespan, from infants in the first minutes of life through the aged population. Congenital abnormalities of lung structure can cause lung disease at birth or make adults more suscept... |
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TMPY-01303
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Serpin A3 Protein, Human, Recombinant (His)
ACT,GIG25,serpin peptidase inhibitor, clade A (alpha-1 antip...
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Human
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HEK293 Cells
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SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a plasma alpha globulin glycoprotein, and is a member of serpin superfamily of the serine protease inhibitors consisting of at least 35 members. SerpinA3 has been demonstrated to inhibit the activity of certain serine proteases, such as cathepsin G found in neutrophils, and chymases present in mast cells, by inducing a major conformational rearrangement, and thus protects some tissues from damage caused by proteolytic enzymes. This enzy... |
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TMPH-02402
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Zinc metalloproteinase Protein, Legionella pneumophila, Recombinant (His)
Zinc metalloproteinase,PEP1,PRO A
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Legionella pneumophila
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E. coli
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Cleaves collagen, gelatin, casein, alpha-1-antitrypsin, and bovine insulin. May play a role in the pathogenesis of legionnaires disease. |
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