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PAQ is a neuroprotective agent. It protects dopaminergic neurons from cell death without inhibiting glial cell proliferation in a rat midbrain culture model of Parkinson's disease when used at a concentration of 10 μM. PAQ (25 or 50 mg/kg, twice per day) prevents loss of dopaminergic neurons in the substantia nigra in a mouse model of Parkinson's disease induced by MPTP.
PAQ is a neuroprotective agent. It protects dopaminergic neurons from cell death without inhibiting glial cell proliferation in a rat midbrain culture model of Parkinson's disease when used at a concentration of 10 μM. PAQ (25 or 50 mg/kg, twice per day) prevents loss of dopaminergic neurons in the substantia nigra in a mouse model of Parkinson's disease induced by MPTP.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 752 | 35日内发货 | |
5 mg | ¥ 3,270 | 35日内发货 | |
10 mg | ¥ 5,810 | 35日内发货 | |
25 mg | ¥ 12,600 | 35日内发货 |
产品描述 | PAQ is a neuroprotective agent. It protects dopaminergic neurons from cell death without inhibiting glial cell proliferation in a rat midbrain culture model of Parkinson's disease when used at a concentration of 10 μM. PAQ (25 or 50 mg/kg, twice per day) prevents loss of dopaminergic neurons in the substantia nigra in a mouse model of Parkinson's disease induced by MPTP. |
分子量 | 221.26 |
分子式 | C14H11N3 |
CAS No. | 943902-10-1 |
密度 | 1.246 g/cm3 (Predicted) |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
溶解度信息 | Ethanol: 2 mg/mL (9.04 mM), Sonication is recommended. DMSO: 10 mg/mL (45.2 mM), Sonication is recommended. DMF: 10 mg/mL (45.2 mM), Sonication is recommended. DMSO:PBS (pH 7.2) (1:1): 0.5 mg/mL (2.26 mM), Sonication is recommended. | |||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||
Ethanol/DMSO/DMF
DMSO/DMF
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