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Imidaprilate, an active metabolite of TA-6366, is a potent angiotensin-converting enzyme (ACE) inhibitor (IC50: 2.6 nM) used in hypertension research.
Imidaprilate, an active metabolite of TA-6366, is a potent angiotensin-converting enzyme (ACE) inhibitor (IC50: 2.6 nM) used in hypertension research.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
500 μg | ¥ 2,780 | 35日内发货 | |
1 mg | ¥ 4,900 | 35日内发货 |
产品描述 | Imidaprilate, an active metabolite of TA-6366, is a potent angiotensin-converting enzyme (ACE) inhibitor (IC50: 2.6 nM) used in hypertension research. |
靶点活性 | ACE:2.6 nM |
体外活性 | Imidaprilate augments the bradykinin-induced contraction of guinea pig ileum, with AC50 of 1.7 nM.Imidaprilate ?is an active metabolite of 6366, acts as a potent angiotensin converting enzyme (ACE) inhibitor, with an IC50 of 2.6 nM. |
体内活性 | Imidaprilate (≥0.2 mg/kg) inhibits the pressor response induced by angiotensin I (AT-I). |
别名 | Imidaprilat, 6366A |
分子量 | 377.39 |
分子式 | C18H23N3O6 |
CAS No. | 89371-44-8 |
密度 | 1.356 g/cm3 (Predicted) |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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