FAPy-adenine

Name: FAPy-adenine
Brand: TargetMol
SKU: T19320
Price: 249 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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产品编号 T19320Cas号 5122-36-1

FAPy-adenine is an oxidized DNA base.Adenine is on the rise in the brains of people with Alzheimer's disease.Nucleoside oxidation is a biochemical marker for tumors, senescence and neurodegenerative diseases.

FAPy-adenine

还可以

产品编号 T19320Cas号 5122-36-1

规格	价格	库存
2 mg	¥ 312	5日内发货
5 mg	¥ 518	5日内发货
10 mg	¥ 828	5日内发货
1 mL x 10 mM (in DMSO)	¥ 913	5日内发货

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产品介绍

生物活性

产品描述	FAPy-adenine is an oxidized DNA base.Adenine is on the rise in the brains of people with Alzheimer's disease.Nucleoside oxidation is a biochemical marker for tumors, senescence and neurodegenerative diseases.
体外活性	In the absence of the external field the FAPy-adenine is able to form pairs with all four canonical nucleic acid bases.?In contrast, in the presence of the external field the mispairing abilities of FAPy-adenine become insignificant since the most stable dimers are formed with thymine
体内活性	The nuclear DNA damage by oxygen-derived radicals is increased in Alzheimer's disease and support the concept that the brain is under increased oxidative stress in Alzheimer's disease.