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[D-Ser14]-Humanin 是通过将Humanin中的Ser14残基由L型替换为D型而得到的生物活性多肽.在抑制amyloid-β纤维的形成方面,[D-Ser14]-Humanin展现出了显著的活性.它能阻止因amyloid-β原纤维和氧化压力导致的多种细胞衰老相关死亡,且其细胞保护活性优于原始的Humanin.此外,[D-Ser14]-Humanin 也被广泛应用于阿尔兹海默症的相关研究.
[D-Ser14]-Humanin 是通过将Humanin中的Ser14残基由L型替换为D型而得到的生物活性多肽.在抑制amyloid-β纤维的形成方面,[D-Ser14]-Humanin展现出了显著的活性.它能阻止因amyloid-β原纤维和氧化压力导致的多种细胞衰老相关死亡,且其细胞保护活性优于原始的Humanin.此外,[D-Ser14]-Humanin 也被广泛应用于阿尔兹海默症的相关研究.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 期货 | |
50 mg | 询价 | 期货 |
产品描述 | [D-Ser14]-Humanin is a biologically active peptide in which the Ser14 residue of Humanin is replaced with its D-form. This variant exhibits effective inhibitory activity against the fibrillation of amyloid-β. Compared to its L-form counterpart, [D-Ser14]-Humanin offers enhanced cellular protective activity against age-related cell death induced by amyloid precursor fibrils and oxidative stress. This compound is utilized in research on Alzheimers disease. |
分子量 | 2687.23 |
分子式 | C119H204N34O32S2 |
CAS No. | 570382-85-3 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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