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β-Secretase Inhibitor II is a tripeptide aldehyde compound that acts as an inhibitor of β-Secretase. It exhibits a simple structure and has an inhibitory potency of IC50 = 700 nM against total Aβ and IC50 = 2.5 μM specifically against Aβ 1-42. This compound is particularly useful in research related to Alzheimer's disease.
β-Secretase Inhibitor II is a tripeptide aldehyde compound that acts as an inhibitor of β-Secretase. It exhibits a simple structure and has an inhibitory potency of IC50 = 700 nM against total Aβ and IC50 = 2.5 μM specifically against Aβ 1-42. This compound is particularly useful in research related to Alzheimer's disease.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 mg | ¥ 10,600 | 期货 |
产品描述 | β-Secretase Inhibitor II is a tripeptide aldehyde compound that acts as an inhibitor of β-Secretase. It exhibits a simple structure and has an inhibitory potency of IC50 = 700 nM against total Aβ and IC50 = 2.5 μM specifically against Aβ 1-42. This compound is particularly useful in research related to Alzheimer's disease. |
靶点活性 | β-Amyloid (1–42):2.5 μM (IC50), β-Amyloid:700 nM (IC50) |
体外活性 | β-Secretase Inhibitor II is a simple tripeptide aldehyde (IC 50 =700 nM for inhibition of total Aβ and IC 50 =2.5 μM for Aβ 1–42 ). β-Secretase Inhibitor II inhibits the formation of both total Aβ and Aβ 1–42 in a dose-dependent manner[1]. |
分子量 | 461.59 |
分子式 | C25H39N3O5 |
CAS No. | 263563-09-3 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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