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Search Results for " activation "

Targets Recommended: NF-κB DNA/RNA Synthesis

1018

抑制剂 & 化合物

291

天然产物

11

化合物库

740

重组蛋白

10

同位素标记化合物

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Cat. No.	Product Name
L1120	AMPK靶向分子库		80 compounds
	80 个靶向AMPK 的分子集合，可用于高通量和高内涵筛选；
L4300	Wnt/Hedgehog/Notch 通路化合物库		237 compounds
	237 个Wnt & Hedgehog & Notch 靶点相关的生物活性小分子化合物的特有集合，用于相关通路的研究及药物的筛选，可用于高通量、高内涵筛选。
L3500	组蛋白修饰化合物库		469 compounds
	469 个组蛋白修饰相关的小分子化合物的特有集合，用于高通量、高内涵筛选；
L1400	MAPK 抑制剂库		365 compounds
	365 种与MAPK 信号通路相关的生物活性小分子化合物的特有集合，可用于高通量筛选和高内涵筛选；
L1200	表观遗传库		953 compounds
	953 种表观遗传学研究相关的生物活性小分子的特有集合，用于表观遗传学研究及其相关的检测和高通量、高内涵筛选；
L9840	抗阿尔茨海默症化合物库		986 compounds
	986 种阿尔茨海默症相关的化合物集合，可用于高通量和高内涵筛选；
L3700	JAK-STAT 化合物库		252 compounds
	252 个 JAK/STAT 靶点相关的小分子化合物的独特集合，用于高通量、高内涵筛选；
L8300	染色质修饰分子库		250 compounds
	250 种染色质化学修饰相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L1300	PI3K/Akt/mTOR 化合物库		420 compounds
	420 种与PI3K/Akt/mTOR 相关的生物活性小分子化合物的特有集合，用于PI3K/Akt/mTOR 相关研究以及高通量、高内涵筛选；
L3800	NF-κB 通路分子库		729 compounds
	729 个 NF-κB 信号通路相关的小分子化合物的特有集合，用于高通量、高内涵筛选；
L8720	细胞焦亡化合物库		1066 compounds
	1066 种细胞焦亡相关的化合物，可以用于细胞焦亡相关研究。

化合物库

AMPK靶向分子库

Cat.No: L1120

Compounds: 80

Wnt/Hedgehog/Notch 通路化合物库

Cat.No: L4300

Compounds: 237

组蛋白修饰化合物库

Cat.No: L3500

Compounds: 469

MAPK 抑制剂库

Cat.No: L1400

Compounds: 365

表观遗传库

Cat.No: L1200

Compounds: 953

抗阿尔茨海默症化合物库

Cat.No: L9840

Compounds: 986

JAK-STAT 化合物库

Cat.No: L3700

Compounds: 252

染色质修饰分子库

Cat.No: L8300

Compounds: 250

PI3K/Akt/mTOR 化合物库

Cat.No: L1300

Compounds: 420

NF-κB 通路分子库

Cat.No: L3800

Compounds: 729

细胞焦亡化合物库

Cat.No: L8720

Compounds: 1066

Cat. No.	Product Name	Target	Signaling Pathways
T9656	AP-1/NF-κB activation inhibitor 1	NF-κB; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; NF-κB
	AP-1/NF-κB activation inhibitor 1 是一种有效的 AP-1和 NF-κB 介导的转录激活抑制剂(IC50=1 μM)，不阻断 β-actin 启动子驱动的基础转录。AP-1/NF-κB activation inhibitor 1 对受刺激细胞中 IL-2和 IL-8的产生水平有相似的抑制作用。
T8705	BOT-64	IκB/IKK	NF-κB
	BOT-64 是一种 IKK-2 抑制剂，靶向激酶激活环结构域中的 Ser177 和/或 Ser181 残基。BOT-64 是一种可渗透细胞的苯并恶硫醇化合物。
T22115	SM-7368	NF-κB	NF-κB
	NF-κB Activation Inhibitor III 是一种NF-kB 抑制剂，抑制 TNF-α 诱导的MMP-9上调，靶向抑制下游的MAPK p38，可用于靶向 TNF-α 介导的肿瘤侵袭和转移的化疗研究。
T80543	STE-MEK1(13) ERK Activation Inhibitor Peptide,Ste-MPKKKPTPIQLNP-NH₂	ERK	MAPK
	STE-MEK1(13)（Ste-MPKKKPTPIQLNP-NH2）为一细胞渗透性ERK1/2抑制剂，IC50值为13-30μM，可抑制ERK1/2磷酸化。
T5697	BMS-1166	PD-1/PD-L1	Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation
	BMS-1166 是 PD-1/PD-L1免疫检查点抑制剂。它促使 PD-L1 形成 PD-L1 同源二聚体，进而阻断其与 PD-1 的相互作用，其 IC50为 1.4 nM。它阻断了 PD-1/PD-L1 免疫检查点对 T 细胞活化的抑制作用。
T15485	HJC0197	cAMP; Ras	GPCR/G Protein; MAPK
	HJC0197 是Epac1(cAMP 1 直接激活的交换蛋白) 和Epac2 拮抗剂，其对Epac2 的IC50值为5.9 μM。它在等浓度 cAMP 存在下能够降低 Epac1 介导的 Rap1-GDP 交换活性。它能够选择性阻断 cAMP 诱导的 Epac 活化。
T6594	MNS	Syk; Src; p97	Angiogenesis; Tyrosine Kinase/Adaptors; Ubiquitination
	MNS 是一种酪氨酸激酶抑制剂和广谱抗血小板药物，是一种 β-硝基苯乙烯衍生物。它完全抑制 U46619 (IC50:2.1 μM)、ADP (IC50:4.1 μM)、花生四烯酸 (IC50:5.8 μM)、胶原 (IC50:7.0 μM)和凝血酶 (IC50:12.7 μM)诱导的血小板聚集，并抑制 Src (IC50:27.3 μM)、Syk (IC50:2.8 μM) 和 FAK (IC50:97.6 μM)。
T13176	TNO155 Batoprotafib	Phosphatase	Metabolism
	TNO155 是具有口服活性野生型SHP2的选择性变构抑制剂 (IC50= 0.011 µM)。它有研究 RTK 依赖性恶性肿瘤（尤其是晚期实体瘤）的潜力。
T11095L	DREADD agonist 21	5-HT Receptor; Adrenergic Receptor; AChR; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	DREADD agonist 21 是一种人毒蕈碱乙酰胆碱 M3 受体激动剂，EC50为 1.7 nM。
T22012	7BIO	FLT; DYRK; Aurora Kinase	Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Tyrosine Kinase/Adaptors
	7BIO 是靛玉红的衍生物，抑制细胞周期蛋白依赖性激酶5 和糖原合酶激酶-3β。它抑制 Aβ 寡聚体诱导的神经炎症、突触损伤、tau 过度磷酸化、星形胶质细胞和小胶质细胞的活化，并减轻 Aβ 寡聚体诱导的小鼠认知障碍。
T8719	SC99	Apoptosis; JAK; STAT	Angiogenesis; Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
	SC99 是一种口服有效选择性STAT3抑制剂，靶向 JAK2-STAT3 途径，抑制血小板活化和聚集，有抗骨髓瘤和抗血栓活性。它结合在 JAK2 的 ATP 结合袋中，抑制 JAK2 和 STAT3 的磷酸化。
T9962	Mepolizumab 美泊利单抗,SB 240563	IL Receptor	Immunology/Inflammation
	Mepolizumab (SB 240563) 是一种中和 IL-5 的人源化单克隆抗体。美泊利单抗可用于严重嗜酸性哮喘和嗜酸性肉芽肿伴多血管炎的研究。
T20759	XRP44X XRP-44-X,XRP 44X,XRP-44X,XRP 44 X	Ras	GPCR/G Protein; MAPK
	XRP44X (XRP 44X) 是Ras 诱导的转录激活的抑制剂，IC50为 10 nM，通过 FGF-2 抑制 Ras-Erk-1/2 通路激活。它抑制Elk3。它还对微管有影响。
T8978	DD1 3,3'-Diamino-4'-methoxyflavone,HUN85111	Proteasome	Proteases/Proteasome; Ubiquitination
	DD1 (HUN85111) 是一种蛋白酶体抑制剂，可诱导人髓系肿瘤选择性凋亡。
T20789	S-23 (S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide,S23	Androgen Receptor	Endocrinology/Hormones
	S-23 ((S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide) 是口服选择性雄激素受体调节剂(Ki:1.7 nM)。它能够诱导 CV-1 细胞雄激素受体介导的转录激活，提高去势大鼠前列腺、精囊和肛提肌重量。
T4205	AG-494 Tyrphostin AG-494,AG 494,Tyrphostin B48	EGFR; CDK	Angiogenesis; Cell Cycle/Checkpoint; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	AG-494 (Tyrphostin B48) 是一种高效、选择性的 EGFR 酪氨酸激酶抑制剂，IC50为0.7 μM。它阻断 Cdk2 的激活并抑制 EGF 依赖的 DNA 合成。它抑制 EGFR、ErbB2、HER1-2 和 PDGF-R 的自磷酸化，IC50为 1.1、39、45 和 6 μM。
T6379	AMG 517 AMG517,N-[4-[[6-[4-(三氟甲基)苯基]-4-嘧啶基]氧基]-2-苯并噻唑基]乙酰胺,AMG-517	TRP/TRPV Channel	Membrane transporter/Ion channel
	AMG 517是一种有效的香草素受体-1 (TRPV1) 拮抗剂，IC50为0.5 nM。
T11234	ESI-08	cAMP	GPCR/G Protein
	ESI-08 是 EPAC2 的有效拮抗剂，IC50 为 8.4 μM。 ESI-08 特异性阻断 cAMP 诱导的 EPAC 活化，但不阻断 cAMP 介导的 PKA 活化。
T12834	Saroglitazar Magnesium	Others	Others
	Saroglitazar Magnesium 是一种新型过氧化物酶体增殖物激活受体(PPAR)激动剂，对PPARα （EC50 0.65pM）具有显著的激活活性以及对PPARγ（EC50 3 nM）有中等的激活活性。
T1897	MDL-29951	NMDAR; iGluR	Membrane transporter/Ion channel; Neuroscience
	MDL 29951 是一种新颖的 nMDA receptor 拮抗剂，能够抑制体内体外甘氨酸 ([3H]glycine) 的结合，Ki=0.14 μM。
T22119	NS3694	Apoptosis	Apoptosis
	NS3694 是一种凋亡抑制剂，可抑制凋亡小体形成和半胱天冬酶活化。
T10977	DCEBIO	Potassium Channel	Membrane transporter/Ion channel
	DCEBIO 是1-EBIO 的衍生物，是 T84 结肠细胞中Cl-分泌的极有效的激活剂。DCEBIO 通过激活 hIK1 K+通道和顶端膜的 Cl-传导促进 Cl-的分泌。
T9853	STING activator Compound 53	STING	Immunology/Inflammation
	基于 oxindole 核心结构的 STING activator Compound 53 在永生化细胞和原代细胞中表现出强大的 STING（人 EC50 185 nM）的靶向功能激活以及与 STING 激活一致的细胞因子诱导指纹。
T32613	LCB 03-0110 dihydrochloride	Src	Angiogenesis; Tyrosine Kinase/Adaptors
	LCB 03-0110 Dihydrochloride 是BTK 和SYK 家族以及DDR2家族中c-Src 激酶（IC50=1.3 nM）和酪氨酸激酶的有效抑制剂。在体外抑制LPS 诱导的巨噬细胞活化和TGF-β1诱导的成纤维细胞活化，抑制巨噬细胞和成纤维细胞的活化，并抑制伤口愈合模型中的瘢痕形成。
T30077	Anisperimus LF 150195,LF-150195,LF 15-0195,LF-15-0195,LF15-0195	Caspase	Apoptosis; Proteases/Proteasome
	Anisperimus (LF 15-0195) 是一种免疫抑制剂，通过促进 DISC 水平的 caspase-8 和 caspase-10 激活来增强激活诱导的 T 细胞死亡，通过促进表达 Foxp3 的调节性 CD4 T 细胞的发育来预防中枢神经系统自身免疫。
T15247	ESI-05 NSC 116966	cAMP	GPCR/G Protein
	ESI-05 (NSC-116966) 是特异性的 cAMP 直接激活交换蛋白 2 (EPAC2) 拮抗剂(IC50:0.4 µM)，能够抑制 cAMP 诱导的 EPAC2 的活化，并 EAPC2 介导的 Rap1 的活化。
T7676	LSKL, Inhibitor of Thrombospondin TSP-1 2TFA LSKL, Inhibitor of Thrombospondin TSP-1	TGF-beta/Smad	Stem Cells
	LSKL, Inhibitor of Thrombospondin TSP-1 2TFA 是 TGF-β 的激活剂。
T9156	CDC25B-IN-2	Phosphatase; mTOR	Metabolism; PI3K/Akt/mTOR signaling
	BIA 是一种 cdc25B 抑制剂。
T1237	Azathioprine 硫唑嘌呤,BW 57-322	Apoptosis; GPR; Rho	Apoptosis; Cell Cycle/Checkpoint; Endocrinology/Hormones; GPCR/G Protein
	Azathioprine (BW 57-322) 是一种免疫抑制剂。
T9734	InhA-IN-2	CDK	Cell Cycle/Checkpoint
	InhA-IN-2直接抑制 InhA，不需要过氧化氢酶过氧化物酶 KatG 的激活。
T15633	JW74	Wnt/beta-catenin	Cytoskeletal Signaling; Stem Cells
	JW74 能够拮抗 LiCl 诱导的经典 Wnt 信号激活 (IC50: 420 nM)。
T3626	Acalabrutinib ACP-196,阿可替尼	BTK	Angiogenesis; Tyrosine Kinase/Adaptors
	Acalabrutinib (ACP-196) 是一种不可逆的、高效的、具有口服活性、选择性的第二代BTK 抑制剂。它与 BTK 的 ATP 结合口袋中的 Cys481 共价结合。它在慢性淋巴细胞性白血病 (CLL) 小鼠模型中显示出强大的靶向作用和功效。
T12705	Reparixin L-lysine salt REPERTAXIN L-赖氨酸盐,Repertaxin L-lysine salt	CXCR	Autophagy; GPCR/G Protein; Immunology/Inflammation
	Reparixin L-lysine salt (Repertaxin L-lysine salt) 是趋化因子受体1/2 活化的变构抑制剂。
T77628	Bisindolylmaleimide III	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC).Bisindolylmaleimide III selectively interacts with PKCα or ribosomal S6 protein kinase 1 upon activation of these kinases.
T22089	HPI 1	Hedgehog/Smoothened	GPCR/G Protein; Stem Cells
	HPI 1 是一种刺猬 (Hh) 信号抑制剂。在 Shh-LIGHT2 细胞中抑制 Sonic Hedgehog (Shh)-、SAG- 和 Gli 诱导的 Hh 通路激活（Shh-、SAG-、Gli2- 和 Gli1 诱导的激活的 IC50 值为 1.5、1.5、4 和 6 μM） .
T8655	SR-717	STING	Immunology/Inflammation
	SR-717 是一种 cGAMP 的类似物，一种非核苷类 STING 激动剂，可以诱导 STING 形成“封闭”的激活构象。SR-717 具有抗肿瘤活性，可以促进免疫细胞的激活以及抗原的交叉提呈。
T18902	6-FAM 6-Carboxyfluorescein,6-羧基荧光素	Others	Others
	6-FAM (6-Carboxyfluorescein) 是一种羧基荧光素的同分异构体，常用作核酸的测序和标记。
T1893	Parmodulin 2 ML 161	Protease-activated Receptor	GPCR/G Protein
	Parmodulin 2 (ML 161) 是一种蛋白酶激活受体 1(PAR1) 变构抑制剂，IC50为 0.26 μM。它是蛋白酶激活受体 1 (PAR1) 介导的血小板活化的抑制剂，可以抑制体外血小板聚集和体内血小板血栓形成。
T15943	M443	p38 MAPK; Chk	Cell Cycle/Checkpoint; MAPK
	M443 是一种高效的 MRK 小分子抑制剂，抑制辐射诱导的 p38 和 Chk2 的激活，可用于研究癌症。
T68022	Sulotroban	PPAR	DNA Damage/DNA Repair; Metabolism
	sulotroban 是一种TXA2受体拮抗剂，与伊洛前列素具有协同作用，可抑制TXA2依赖性血小板活化。
T6322	Copanlisib BAY 80-6946,可泮利塞,库潘尼西	Apoptosis; PI3K	Apoptosis; PI3K/Akt/mTOR signaling
	Copanlisib (BAY 80-6946) 是一种选择性的和 ATP 竞争性的泛 I 类PI3K 抑制剂，具有抗肿瘤活性，对PI3Kα，PI3Kδ，PI3Kβ和PI3Kγ的IC50分别为 0.5 nM、0.7 nM、3.7 nM 和 6.4 nM。
TQ0305	CID-2858522	NF-κB	NF-κB
	CID-2858522 是有效的、选择性抗原受体介导的NF-κB 抑制剂，IC50为 70 nM。
T72112	Clozapine N-oxide dihydrochloride	AChE	Neuroscience
	Clozapine N-oxide dihydrochloride 是一种 Clozapine 的衍生物，也是一种可穿过血脑屏障的人毒蕈碱设计受体 (DREADDs) 激动剂。Clozapine N-oxide dihydrochloride 诱导 DREADD 受体 hM3Dq 和 hM4Di激活。
T9266	Fatostatin	Lipid; Fatty Acid Synthase	Metabolism
	Fatostatin A 是一种SREBP 活化的特异性抑制剂，能够抑制 SREBP-1 和 SREBP-2 的活化。它与 SCAP (SREBP 裂解激活蛋白) 结合，抑制 SREBPs 的 ER-Golgi 易位。它具有抗肿瘤活性，能抑制ob/ob 小鼠的高血糖。它抑制细胞中成脂基因的转录。
T28865	STAT3-IN-B9 STAT3 IN B9,B9	STAT	JAK/STAT signaling; Stem Cells
	STAT3-IN-B9 (B9) 是异常 STAT3 激活的抑制剂，可抑制 MDA-MB-468、MDA-MB-231 和 DU145 等肿瘤细胞的增殖。
T14680	BMS-906024 Osugacestat,AL-101,BM-0018	Gamma-secretase	Neuroscience; Proteases/Proteasome; Stem Cells
	BMS-906024 (Osugacestat) 是一种可口服且具有选择性的γ 分泌酶抑制剂，是一种小分子 Notch 抑制剂。BMS-906024 对多种人类癌症异种移植具有广谱抗肿瘤活性。BMS-906024 可阻止所有四种 Notch 受体的激活，对 Notch1、-2、-3 和 -4 受体的 IC50 分别为 1.6、0.7、3.4 和 2.9 nM。
T6610	XI-006 NSC 207895,可可碱	Mdm2; p53	Apoptosis
	XI-006 (XI-006) 是一种DNA 破坏剂、抗肿瘤剂和p53的激活剂。
T5349	SCR-1481B1 麦他替尼胺丁三醇,c-Met inhibitor 2	VEGFR; c-Met/HGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	SCR-1481B1 (c-Met inhibitor 2) 能够作用于依赖 Met 激活的癌症，对 VEGFR 具有抑制作用。
T23497	UK 78282 hydrochloride	Potassium Channel	Membrane transporter/Ion channel
	UK 78282 hydrochloride，一种新型有效且具有选择性的 Kv1.3 阻滞剂。UK 78282 hydrochloride 抑制 Kv1.3 电压门控钾通道，抑制人 T 细胞活化。
T19651	Isoflurane HSDB-8057,Forane,HSDB 8057,异氟醚,HSDB8057,Terrell	Others	Others
	Isoflurane (Forane) 是一种稳定的非爆炸性吸入麻醉剂，据报道可诱导 caspase-3 活化。

化合物

AP-1/NF-κB activation inhibitor 1

Cat.No: T9656

Target: NF-κB, DNA/RNA Synthesis

Cat.No: T8705

Target: IκB/IKK

Cat.No: T22115

Target: NF-κB

Cat.No: T80543

Synonym: ERK Activation Inhibitor Peptide,Ste-MPKKKPTPIQLNP-NH₂

Target: ERK

Cat.No: T5697

Target: PD-1/PD-L1

Cat.No: T15485

Target: cAMP, Ras

Cat.No: T6594

Target: Syk, Src, p97

Cat.No: T13176

Synonym: Batoprotafib

Target: Phosphatase

DREADD agonist 21

Cat.No: T11095L

Target: 5-HT Receptor, Adrenergic Receptor, AChR, Histamine Receptor

Cat.No: T22012

Target: FLT, DYRK, Aurora Kinase

Cat.No: T8719

Target: Apoptosis, JAK, STAT

Cat.No: T9962

Synonym: 美泊利单抗,SB 240563

Target: IL Receptor

Cat.No: T20759

Synonym: XRP-44-X,XRP 44X,XRP-44X,XRP 44 X

Target: Ras

Cat.No: T8978

Synonym: 3,3'-Diamino-4'-methoxyflavone,HUN85111

Target: Proteasome

Cat.No: T20789

Synonym: (S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide,S23

Target: Androgen Receptor

Cat.No: T4205

Synonym: Tyrphostin AG-494,AG 494,Tyrphostin B48

Target: EGFR, CDK

Cat.No: T6379

Synonym: AMG517,N-[4-[[6-[4-(三氟甲基)苯基]-4-嘧啶基]氧基]-2-苯并噻唑基]乙酰胺,AMG-517

Target: TRP/TRPV Channel

Cat.No: T11234

Target: cAMP

Saroglitazar Magnesium

Cat.No: T12834

Target: Others

Cat.No: T1897

Target: NMDAR, iGluR

Cat.No: T22119

Target: Apoptosis

Cat.No: T10977

Target: Potassium Channel

STING activator Compound 53

Cat.No: T9853

Target: STING

LCB 03-0110 dihydrochloride

Cat.No: T32613

Target: Src

Cat.No: T30077

Synonym: LF 150195,LF-150195,LF 15-0195,LF-15-0195,LF15-0195

Target: Caspase

Cat.No: T15247

Synonym: NSC 116966

Target: cAMP

LSKL, Inhibitor of Thrombospondin TSP-1 2TFA

Cat.No: T7676

Synonym: LSKL, Inhibitor of Thrombospondin TSP-1

Target: TGF-beta/Smad

Cat.No: T9156

Target: Phosphatase, mTOR

Cat.No: T1237

Synonym: 硫唑嘌呤,BW 57-322

Target: Apoptosis, GPR, Rho

Cat.No: T9734

Target: CDK

Cat.No: T15633

Target: Wnt/beta-catenin

Cat.No: T3626

Synonym: ACP-196,阿可替尼

Target: BTK

Reparixin L-lysine salt

Cat.No: T12705

Synonym: REPERTAXIN L-赖氨酸盐,Repertaxin L-lysine salt

Target: CXCR

Bisindolylmaleimide III

Cat.No: T77628

Target: PKC

Cat.No: T22089

Target: Hedgehog/Smoothened

Cat.No: T8655

Target: STING

Cat.No: T18902

Synonym: 6-Carboxyfluorescein,6-羧基荧光素

Target: Others

Cat.No: T1893

Synonym: ML 161

Target: Protease-activated Receptor

Cat.No: T15943

Target: p38 MAPK, Chk

Cat.No: T68022

Target: PPAR

Cat.No: T6322

Synonym: BAY 80-6946,可泮利塞,库潘尼西

Target: Apoptosis, PI3K

Cat.No: TQ0305

Target: NF-κB

Clozapine N-oxide dihydrochloride

Cat.No: T72112

Target: AChE

Cat.No: T9266

Target: Lipid, Fatty Acid Synthase

Cat.No: T28865

Synonym: STAT3 IN B9,B9

Target: STAT

Cat.No: T14680

Synonym: Osugacestat,AL-101,BM-0018

Target: Gamma-secretase

Cat.No: T6610

Synonym: NSC 207895,可可碱

Target: Mdm2, p53

Cat.No: T5349

Synonym: 麦他替尼胺丁三醇,c-Met inhibitor 2

Target: VEGFR, c-Met/HGFR

UK 78282 hydrochloride

Cat.No: T23497

Target: Potassium Channel

Cat.No: T19651

Synonym: HSDB-8057,Forane,HSDB 8057,异氟醚,HSDB8057,Terrell

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T5552	Methyl cinnamate	Tyrosinase; Antibacterial; AMPK	Chromatin/Epigenetic; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Methyl cinnamate 是花椒的有效成分，也是一种天然香料。它是一种防止食品褐变的酪氨酸酶抑制剂，具有抗菌活性。它通过由 CaMKK2-AMPK 信号途径介导的机制具有抗脂活性。
T9352	hydrocotarnine	Others	Others
	hydrocotarnine 是 Cbl 的抑制剂。
T3S2072	3-Butylidenephthalide Butylidene phthalide,n-Butylidenephthalide,丁烯基苯酞,丁烯基苯酞；丁烯基酞内酯	Parasite; Glucosidase	Metabolism; Microbiology/Virology
	3-Butylidenephthalide (Butylidene phthalide) 是从 Ligusticum chuanxiongHort 鉴定出的一种邻苯二甲酸酐衍生物，有杀虫活性。
T1633	β-Carotene beta-胡萝卜素,Carotaben,Beta-Carotene,Provitamin A,β-胡萝卜素	Apoptosis; ROS; Endogenous Metabolite	Apoptosis; Immunology/Inflammation; Metabolism
	β-Carotene (Provitamin A) 是一种天然存在的视黄醇（维生素 A）前体。它是一种 ROS 调节剂，具有抗氧化和抗炎活性。它可作为抗氧化剂或者促氧化剂，可诱导乳腺癌细胞凋亡，具有抗癌活性。
T3385	Gypenoside XVII GP-17,Gynosaponin S,七叶胆苷XVII	Estrogen Receptor/ERR; GSK-3; Endogenous Metabolite	Endocrinology/Hormones; Metabolism; PI3K/Akt/mTOR signaling; Stem Cells
	Gypenoside XVII (Gynosaponin S) 是一种绞股蓝皂甙类的新型植物雌激素，能够激活雌激素受体。
T8678	Naphthazarin 萘茜,5,8-Dihydroxy-1,4-naphthoquinone,DHNQ	Apoptosis	Apoptosis
	Naphthazarin (5,8-Dihydroxy-1,4-naphthoquinone) 是来自毛紫草的一种天然产物，通过氧化应激、线粒体凋亡诱导因子的激活、微管的解聚、干扰溶酶体功能和 p53 依赖性 p21 激活，可触发细胞凋亡并具有抗肿瘤作用。
T9328	Ellagic Acid Dihydrate	P450	Metabolism
	Ellagic Acid Dihydrate 抑制 CYP1A1 依赖的benzo[a]pyrene 活化。
TQ0185	14-Deoxy-11,12-didehydroandrographolide AP10,14-脱氧-11,12-二去氢穿心莲内酯,14-dehydro Andrographolide	NF-κB	NF-κB
	14-Deoxy-11,12-didehydroandrographolide (AP10) 是一种 Andrographolide 的类似物，能够抑制 NF-κB 活性。
T5S1895	Norisoboldine Laurelliptine,去甲异波尔定,(+)-Laurelliptine	MAPK; Adenosine Receptor	GPCR/G Protein; MAPK; Neuroscience
	Norisoboldine ((+)-Laurelliptine) 是一种可口服的芳基烃受体激动剂，是乌药中主要的异喹啉类生物碱，可用于类风湿性关节炎和溃疡性结肠炎的研究。
T19711	Desmosterol Desmesterol,24-Dehydrocholesterol	Endogenous Metabolite	Metabolism
	Desmosterol(24-Dehydrocholesterol) 是一种胆固醇生物合成中间体，抑制巨噬细胞炎症小体活化，防止血管炎症和动脉粥样硬化。
TN1131	Handelin	NF-κB; Immunology/Inflammation related	Immunology/Inflammation; NF-κB
	Handelin 是一种来自 Chrysanthemum boreale 的愈创木酚内酯二聚体，它能够阻碍 NF-κB 活化和促炎细胞因子产生，具有抗炎作用。
T4037	Phorbol 4β-Phorbol,佛波醇,(+)-Phorbol	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	Phorbol (4β-Phorbol) 是具有毒性的二萜类化合物，其酯类具有强大的生物活性。
TN2346	Mogrol	ERK; AMPK; STAT	Chromatin/Epigenetic; JAK/STAT signaling; MAPK; PI3K/Akt/mTOR signaling; Stem Cells
	Mogrol 是罗汉果中的一种天然产物，通过抑制 ERK1/2 和 STAT3 通路，减少 CREB 激活和激活 AMPK 信号传导发挥作用。
TN3016	4',6,7-Trimethoxyisoflavone	MMP	Proteases/Proteasome
	4',6,7-Trimethoxyisoflavone 通过 NOX2 诱导促进伤口愈合，从而导致集体迁移和 MMP 活化。
TN2063	Physalin B NSC-287088	Apoptosis; NF-κB; Akt; PI3K; Nrf2; NOD	Apoptosis; Cytoskeletal Signaling; Immunology/Inflammation; NF-κB; PI3K/Akt/mTOR signaling
	Physalin B 是茄科植物的主要活性化合物之一，具有广泛的生物活性，可用于治疗炎症湿疹和疱疹等疾病。Physalin B 通过激活 PI3K/Akt 通路抑制 NF-κB 和 NLRP3，从而改善脂多糖诱导的急性肺损伤造成的炎症反应。Physalin B 通过激活 Nrf2 通路抑制 PDGF-BB 诱导的 VSMC 增殖、迁移和表型转化。Physalin B 通过抑制 LAP2α-HDAC1 介导的胶质瘤相关癌基因 1 的去乙酰化和肝星状细胞活化来发挥抗肿瘤活性。
T5S1261	Methylophiopogonanone B	Ras	GPCR/G Protein; MAPK
	Methylophiopogonanone B 是一种高异二氢黄酮，提取自麦冬的根，抗氧化能力强，它通过 Rho 信号传导途径及增加 GTP-Rho 发挥效果。它能够重组肌动蛋白细胞骨架，使细胞形态（如树突收缩、应力纤维形成）发生变化。
T5S0168	Atractylenolide II 2-Atractylenolide,Asterolide,苍术内酯II	Apoptosis; ERK; p38 MAPK; Akt; STAT	Apoptosis; Cytoskeletal Signaling; JAK/STAT signaling; MAPK; PI3K/Akt/mTOR signaling; Stem Cells
	Atractylenolide II (2-Atractylenolide) 是一种从白术干燥根茎分离的倍半萜类天然产物，具有抗增殖活性。
TN1096	Ginsenoside Ra1 人参皂苷 Ra1,人参皂苷Ra1	Others; Tyrosine Kinases	Others; Tyrosine Kinase/Adaptors
	Ginsenoside Ra1 是来自人参的成分。 Ginsenoside Ra1 对缺氧/复氧诱导的蛋白酪氨酸激酶 (PTK) 活化具有显着抑制作用。
T10183	6-Methoxytricin	Reductase	Endocrinology/Hormones; Metabolism
	6-Methoxytricin 是从积雪草中分离的黄酮类化合物，是醛糖还原酶 (AR) 和晚期糖基化终产物 (AGE) 的抑制剂，抑制生物细胞中的T细胞增殖和活化。
T5798	Euphorbia Factor L2 千金子素L2,euphorbiafactor L2,大戟因子L2	Apoptosis; NF-κB	Apoptosis; NF-κB
	Euphorbia Factor L2 是从大戟种子中分离得到的一种赤藓烷二萜，显示强烈的细胞毒性并通过线粒体途径诱导细胞凋亡，具有抗癌活性。
T10117	3'-O-Acetylhamaudol	Others	Others
	3'-O-Acetylhamaudol 是提取于 Angelica japonica 根部，能够抗血管生成和激活肠上皮淋巴细胞，具有抗肿瘤活性。
T40660	Kansuinine B	IL Receptor; SARS-CoV	Immunology/Inflammation; Microbiology/Virology
	Kansuinine B 抑制由 IL-6 诱导的 Stat3 活化。 Kansuinine B 具有抗病毒活性，可用于 COVID-19 研究。
T3806	kaempferide Kaempferol 4'-O-methyl ether,山奈素,Kaempferol 4'-methyl ether,4'-Methylkaempferol,4'-O-Methylkaempferol	Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Influenza Virus; Antibacterial; Autophagy	Autophagy; Endocrinology/Hormones; Microbiology/Virology
	kaempferide (4'-Methylkaempferol) 是一种存在于山柰中的O-甲基化黄酮醇，具有抗病毒活性。
T6S1367	Procyanidin B2 原花青素 B2,Proanthocyanidin B2	Reactive Oxygen Species; NOD	Immunology/Inflammation; Metabolism; NF-κB
	Procyanidin B2 (Proanthocyanidin B2) 是天然黄酮类物质，具有抗肿瘤，抗氧化等活性。
TMS2171	(±)-Naringenin (±)-柚皮素,Salipurpol,柚皮素,Naringenine,Naringenin	Potassium Channel	Membrane transporter/Ion channel
	(±)-Naringenin (Naringenine) 是一种天然的类黄酮。它通过激活肌细胞中 BKCa 通道发挥对内皮剥脱血管的舒张作用。
T23735	Jamaicin An-Co-A4,AnCoA-4,An Co A4,AnCoA4	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Jamaicin (AnCoA4) 是一种从鸡血藤植物中提取的异黄酮，是一种 STIM1-Orai1 通道的抑制剂，可阻断钙离子流入，减少其与 STIM1 的相互作用，抑制 T 细胞的活化。
T2823	Crocin 西红花苷,藏红花,Gardenia Yellow,Alpha-Crocin,藏红花素	Others	Others
	Crocin (Gardenia Yellow) 是从Crocus sativus 柱头中分离出的主要成分，是一种营养保健品，具有抗炎，抗癌，抗抑郁和抗惊厥等强大的药理作用。
T8092	Taurohyodeoxycholic acid sodium salt Sodium taurohyodeoxycholate hydrate	Caspase	Apoptosis; Proteases/Proteasome
	Taurohyodeoxycholic acid sodium salt (Sodium taurohyodeoxycholate hydrate) 通过阻断钙介导的细胞凋亡途径以及 Caspase-12 活化来防止细胞凋亡
T3399	Psoralidin	Others; Estrogen/progestogen Receptor; Reactive Oxygen Species; Lipoxygenase; Gamma-secretase; Akt; COX; Antibacterial	Cytoskeletal Signaling; Endocrinology/Hormones; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience; NF-κB; Others; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells
	Psoralidin 是COX-2和5-LOX 的抑制剂，有抗癌，抗菌和抗炎作用。它显著下调NOTCH1信号传导，还极大地诱导活化氧产生。
T9503	PHYTOSPHINGOSINE	Apoptosis	Apoptosis
	Phytosphingosine 是具有抗癌作用的一种磷脂。在癌细胞中，它通过 caspase 8 的激活和 Bax 转位诱导细胞凋亡。
T2854	Phillyrin Forsythin,连翘苷	P450; Influenza Virus; AMPK	Chromatin/Epigenetic; Metabolism; Microbiology/Virology; PI3K/Akt/mTOR signaling
	Phillyrin (Forsythin) 是从连翘中分离出来的一种天然产物，具有抗甲型流感病毒的活性，以及抗菌和消炎作用。
T5079	Adenosine 5'-diphosphate sodium salt 腺苷-5‘-二磷酸钠盐,Adenosine-5'-diphosphate trisodium salt,ADP sodium salt	Others; Endogenous Metabolite	Metabolism; Others
	Adenosine 5'-diphosphate sodium salt (ADP sodium salt) 是一种核苷二磷酸，是一种 ATP 酶对 ATP 去磷酸化的产物。它通过在 P2T-嘌呤受体上的作用诱导人血小板聚集并抑制刺激的腺苷酸环化酶。
TN1110	Shanziside 山栀苷,Shanzhiside	IL Receptor	Immunology/Inflammation
	Shanziside (Shanzhiside) 是一种分离自福洛美属植物中的环烯醚萜苷类化合物。
T2947	Indole-3-carbinol 吲哚-3-甲醇,I3C,3-Indolemethanol,3-吲哚甲醇,Indole-3-Methanol	E1/E2/E3 Enzyme; NF-κB; Aryl Hydrocarbon Receptor; Endogenous Metabolite; p53	Apoptosis; Immunology/Inflammation; Metabolism; NF-κB; Ubiquitination
	Indole-3-carbinol (I3C) 是樟子松中的一种天然产物，是可口服的硫代葡萄糖苷葡糖苷酶裂解产物。它是芳烃受体 (AhR) 的激动剂，可抑制 NF-κB 和 IκBα 激酶活化。
TN1933	Mitraphylline 帽柱木菲碱,帽柱叶碱	IL Receptor; TNF; NF-κB	Apoptosis; Immunology/Inflammation; NF-κB
	Mitraphylline 是一种绒毛钩藤中主要的五环吲哚类生物碱，可阻碍脂多糖介导的原代人中性粒细胞活化。
T3S0872	Paederoside	Antiviral; HBV	Immunology/Inflammation; Microbiology/Virology
	Paederoside 是从Paederia pertomentosa 分离的一种单萜 S-甲基硫代碳酸酯。它抑制 Epstein-Barr 病毒的激活，有抗肿瘤促进作用。
T13803	N-Oleoyl glycine	Cannabinoid Receptor; Akt; Endogenous Metabolite; PPAR	Cytoskeletal Signaling; DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; PI3K/Akt/mTOR signaling
	N-Oleoyl glycine 是一种脂氨酸。在 3T3-L1 脂肪细胞中，N-Oleoyl glycine 通过激活CB1受体和Akt 信号通路来刺激脂肪形成。
T5S1097	Neferine (R)-1,2-Dimethoxyaporphine,(-)-Neferine,甲基莲心碱	Apoptosis; NF-κB; Autophagy	Apoptosis; Autophagy; NF-κB
	Neferine ((-)-Neferine) 是一种双苄基异喹啉类生物碱，可强效抑制NF-κB 激活，具有抗肿瘤活性。
T4S1615	Sanggenon C 桑根酮C,桑根酮 C,Sanggenone C	NF-κB	NF-κB
	Sanggenon C (Sanggenone C) 是一种从桑属的根皮中分离得到的黄烷酮 Diels-Alder 加合物化合物。它可抑制NF-κB 活性，抑制 RAW264.7 细胞中诱导型一氧化氮合酶的表达，以及肿瘤坏死因子-α 刺激的细胞粘附和血管细胞粘附分子-1 的表达。它具有抗氧化和抗炎作用，也有抑制胰脂肪酶作用。
T3000	Magnolol NSC 293099,厚朴酚,5,5'-Diallyl-2,2'-biphenyldiol	NF-κB; Retinoid Receptor; Antibacterial; PPAR; p53; Autophagy	Apoptosis; Autophagy; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology; NF-κB
	Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) 是RXRα和PPARγ的激动剂，EC50值分别为 10.4 µM 和 17.7 µM。他是从厚朴的树皮中分离得到的一种木脂素。
TQ0199	Ginsenoside Rh3 人参皂苷 RH3	Antioxidant; Nrf2; Antifungal	Immunology/Inflammation; Microbiology/Virology; oxidation-reduction
	Ginsenoside Rh3 是一种从人参 C. A. Mey 中提取的天然产品。Ginsenoside Rh3 具有抗真菌和抗氧化活性，处理人视网膜细胞可诱导 Nrf2 。
T10990	Dehydrocorydaline chloride 盐酸脱氢紫堇碱,13-Methylpalmatine chloride	BCL; PARP; p38 MAPK; Caspase; Parasite; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; MAPK; Microbiology/Virology; Proteases/Proteasome
	Dehydrocorydaline chloride (13-Methylpalmatine chloride) 是生物碱。Dehydrocorydaline 调节 Bax，Bcl-2蛋白表达；激活 caspase-7，caspase-8，并使 PARP 失活。它能增强 p38 MAPK 活化，具有抗炎、抗癌等功效。它具有强大的抗疟疾作用，并具低细胞毒性。
T2179	Triptolide PG490,NSC 163062,雷公藤甲素	Apoptosis; Mdm2; HSP; NF-κB	Apoptosis; Cytoskeletal Signaling; Metabolism; NF-κB
	Triptolide (PG490) 属于三环二萜类天然产物，是一种 NF-κB 活化的抑制剂。Triptolide 具有免疫抑制、抗风湿、抗炎、抗增殖和抗肿瘤活性。
TN1879	Lucideric acid A Lucidenic acid A,赤芝酸A	MMP; p38 MAPK; JNK	MAPK; Proteases/Proteasome
	Lucideric acid A (Lucidenic acid A) 是分离自灵芝的天然产物，可抑制 PMA 诱导的MMP-9活性，具有抵抗肝癌细胞侵袭的作用。
T3843	Pinosylvin 银松素,3,5-stilbenediol,5-Styrylresorcinol	Apoptosis; Others; Antibacterial; Autophagy	Apoptosis; Autophagy; Microbiology/Virology; Others
	Pinosylvin (5-Styrylresorcinol) 是从Pinus spp 的心材中分离出来的一种白藜芦醇类似物，可诱导白血病细胞凋亡和自噬。它是一种感染前的类苯乙烯类毒素，具有抗菌活性。
TQ0169	Inulicin 1-O-Acetylbritannilactone,旋覆花内酯	FAK; NF-κB; COX; Src	Angiogenesis; Cytoskeletal Signaling; Immunology/Inflammation; Neuroscience; NF-κB; Tyrosine Kinase/Adaptors
	Inulicin (1-O-Acetylbritannilactone) 是从欧亚旋覆花中提取的一种天然产物，可抑制 VEGF 介导的Src 和FAK 活化，抑制NF-κB 活化和易位，以及抑制 LPS 诱导的PGE2产生和COX-2表达。
T6S1587	Notoginsenoside R2 三七皂苷R2,20(S)-Notoginsenoside R2,Ginsenoside Ng-R2	Others; Nrf2	Immunology/Inflammation; Others
	Notoginsenoside R2 (20(S)-Notoginsenoside R2) 是一种新分离三七皂苷，表现出对6-OHDA 诱导的氧化应激及细胞凋亡的保护作用。
TN1031	Poricoic acid B 茯苓酸B,茯苓新酸 B	Others	Others
	Poricoic acid B 是提取自 Poria cocos 中，拥有抗肿瘤作用。
T5S2358	Dehydrocorydaline Dehydrocorydalin,脱氢紫堇碱,13-Methylpalmatine	BCL; PARP; p38 MAPK; Caspase; Parasite; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; MAPK; Microbiology/Virology; Proteases/Proteasome
	Dehydrocorydaline (13-Methylpalmatine) 是一种生物碱。它调节Bax，Bcl-2蛋白表达，激活caspase-7，caspase-8，并使PARP 失活。它能增强p38 MAPK 活化，具有抗炎、抗癌等功效。它具有强大的抗疟疾作用，并具低细胞毒性。
TN1013	Cucurbitacin D	Apoptosis	Apoptosis
	Cucurbitacin D 是一种从 Ecballium elaterium （L.）分离出来的三萜类化合物，具有抗癌抗肿瘤活性，抑制转移性 PrC 中的葡萄糖摄取和乳酸产生，诱导独立于 ERK1/2 激活的炎症小体激活。 Cucurbitacin D 是巨噬细胞中的一种新的炎症小体激活剂，通过调节 JAK/STAT3、PI3K/Akt/mTOR 和 MAPK 信号通路抑制 HepG2 细胞增殖并诱导细胞凋亡，可用于研究宫颈癌、白血病和前列腺癌。
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天然产物

Methyl cinnamate

Cat.No: T5552

Target: Tyrosinase, Antibacterial, AMPK

Cat.No: T9352

Target: Others

3-Butylidenephthalide

Cat.No: T3S2072

Synonym: Butylidene phthalide,n-Butylidenephthalide,丁烯基苯酞,丁烯基苯酞；丁烯基酞内酯

Target: Parasite, Glucosidase

Cat.No: T1633

Synonym: beta-胡萝卜素,Carotaben,Beta-Carotene,Provitamin A,β-胡萝卜素

Target: Apoptosis, ROS, Endogenous Metabolite

Gypenoside XVII

Cat.No: T3385

Synonym: GP-17,Gynosaponin S,七叶胆苷XVII

Target: Estrogen Receptor/ERR, GSK-3, Endogenous Metabolite

Cat.No: T8678

Synonym: 萘茜,5,8-Dihydroxy-1,4-naphthoquinone,DHNQ

Target: Apoptosis

Ellagic Acid Dihydrate

Cat.No: T9328

Target: P450

14-Deoxy-11,12-didehydroandrographolide

Cat.No: TQ0185

Synonym: AP10,14-脱氧-11,12-二去氢穿心莲内酯,14-dehydro Andrographolide

Target: NF-κB

Cat.No: T5S1895

Synonym: Laurelliptine,去甲异波尔定,(+)-Laurelliptine

Target: MAPK, Adenosine Receptor

Cat.No: T19711

Synonym: Desmesterol,24-Dehydrocholesterol

Target: Endogenous Metabolite

Cat.No: TN1131

Target: NF-κB, Immunology/Inflammation related

Cat.No: T4037

Synonym: 4β-Phorbol,佛波醇,(+)-Phorbol

Target: PKC

Cat.No: TN2346

Target: ERK, AMPK, STAT

4',6,7-Trimethoxyisoflavone

Cat.No: TN3016

Target: MMP

Cat.No: TN2063

Synonym: NSC-287088

Target: Apoptosis, NF-κB, Akt, PI3K, Nrf2, NOD

Methylophiopogonanone B

Cat.No: T5S1261

Target: Ras

Atractylenolide II

Cat.No: T5S0168

Synonym: 2-Atractylenolide,Asterolide,苍术内酯II

Target: Apoptosis, ERK, p38 MAPK, Akt, STAT

Ginsenoside Ra1

Cat.No: TN1096

Synonym: 人参皂苷 Ra1,人参皂苷Ra1

Target: Others, Tyrosine Kinases

6-Methoxytricin

Cat.No: T10183

Target: Reductase

Euphorbia Factor L2

Cat.No: T5798

Synonym: 千金子素L2,euphorbiafactor L2,大戟因子L2

Target: Apoptosis, NF-κB

3'-O-Acetylhamaudol

Cat.No: T10117

Target: Others

Cat.No: T40660

Target: IL Receptor, SARS-CoV

Cat.No: T3806

Synonym: Kaempferol 4'-O-methyl ether,山奈素,Kaempferol 4'-methyl ether,4'-Methylkaempferol,4'-O-Methylkaempferol

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Influenza Virus, Antibacterial, Autophagy

Cat.No: T6S1367

Synonym: 原花青素 B2,Proanthocyanidin B2

Target: Reactive Oxygen Species, NOD

(±)-Naringenin

Cat.No: TMS2171

Synonym: (±)-柚皮素,Salipurpol,柚皮素,Naringenine,Naringenin

Target: Potassium Channel

Cat.No: T23735

Synonym: An-Co-A4,AnCoA-4,An Co A4,AnCoA4

Target: Calcium Channel

Cat.No: T2823

Synonym: 西红花苷,藏红花,Gardenia Yellow,Alpha-Crocin,藏红花素

Target: Others

Taurohyodeoxycholic acid sodium salt

Cat.No: T8092

Synonym: Sodium taurohyodeoxycholate hydrate

Target: Caspase

Cat.No: T3399

Target: Others, Estrogen/progestogen Receptor, Reactive Oxygen Species, Lipoxygenase, Gamma-secretase, Akt, COX, Antibacterial

PHYTOSPHINGOSINE

Cat.No: T9503

Target: Apoptosis

Cat.No: T2854

Synonym: Forsythin,连翘苷

Target: P450, Influenza Virus, AMPK

Adenosine 5'-diphosphate sodium salt

Cat.No: T5079

Synonym: 腺苷-5‘-二磷酸钠盐,Adenosine-5'-diphosphate trisodium salt,ADP sodium salt

Target: Others, Endogenous Metabolite

Cat.No: TN1110

Synonym: 山栀苷,Shanzhiside

Target: IL Receptor

Indole-3-carbinol

Cat.No: T2947

Synonym: 吲哚-3-甲醇,I3C,3-Indolemethanol,3-吲哚甲醇,Indole-3-Methanol

Target: E1/E2/E3 Enzyme, NF-κB, Aryl Hydrocarbon Receptor, Endogenous Metabolite, p53

Cat.No: TN1933

Synonym: 帽柱木菲碱,帽柱叶碱

Target: IL Receptor, TNF, NF-κB

Cat.No: T3S0872

Target: Antiviral, HBV

N-Oleoyl glycine

Cat.No: T13803

Target: Cannabinoid Receptor, Akt, Endogenous Metabolite, PPAR

Cat.No: T5S1097

Synonym: (R)-1,2-Dimethoxyaporphine,(-)-Neferine,甲基莲心碱

Target: Apoptosis, NF-κB, Autophagy

Cat.No: T4S1615

Synonym: 桑根酮C,桑根酮 C,Sanggenone C

Target: NF-κB

Cat.No: T3000

Synonym: NSC 293099,厚朴酚,5,5'-Diallyl-2,2'-biphenyldiol

Target: NF-κB, Retinoid Receptor, Antibacterial, PPAR, p53, Autophagy

Ginsenoside Rh3

Cat.No: TQ0199

Synonym: 人参皂苷 RH3

Target: Antioxidant, Nrf2, Antifungal

Dehydrocorydaline chloride

Cat.No: T10990

Synonym: 盐酸脱氢紫堇碱,13-Methylpalmatine chloride

Target: BCL, PARP, p38 MAPK, Caspase, Parasite, Autophagy

Cat.No: T2179

Synonym: PG490,NSC 163062,雷公藤甲素

Target: Apoptosis, Mdm2, HSP, NF-κB

Lucideric acid A

Cat.No: TN1879

Synonym: Lucidenic acid A,赤芝酸A

Target: MMP, p38 MAPK, JNK

Cat.No: T3843

Synonym: 银松素,3,5-stilbenediol,5-Styrylresorcinol

Target: Apoptosis, Others, Antibacterial, Autophagy

Cat.No: TQ0169

Synonym: 1-O-Acetylbritannilactone,旋覆花内酯

Target: FAK, NF-κB, COX, Src

Notoginsenoside R2

Cat.No: T6S1587

Synonym: 三七皂苷R2,20(S)-Notoginsenoside R2,Ginsenoside Ng-R2

Target: Others, Nrf2

Poricoic acid B

Cat.No: TN1031

Synonym: 茯苓酸B,茯苓新酸 B

Target: Others

Dehydrocorydaline

Cat.No: T5S2358

Synonym: Dehydrocorydalin,脱氢紫堇碱,13-Methylpalmatine

Target: BCL, PARP, p38 MAPK, Caspase, Parasite, Autophagy

Cat.No: TN1013

Target: Apoptosis

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04962	FAP Protein, Cynomolgus, Recombinant (His) fibroblast activation protein, α,fibroblast act...	Cynomolgus	HEK293 Cells
	FAP Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 87 kDa and the accession number is A0A2K5VGF4.
TMPY-05092	LAG-3 Protein, Cynomolgus, Recombinant (74 Pro, His) lymphocyte-activation gene 3	Cynomolgus	HEK293 Cells
	LAG-3 Protein, Cynomolgus, Recombinant (74 Pro, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.4 kDa and the accession number is XP_005570011.1.
TMPY-04922	FAP Protein, Human, Recombinant (His), Biotinylated DPPIV,Fibroblast Activation Protein alpha,DPPIVA,SI...	Human	HEK293 Cells
	FAP Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 87.2 kDa and the accession number is Q12884-1.
TMPY-02154	FAP Protein, Human, Recombinant (His) fibroblast activation protein, alpha,Fibroblast	Human	HEK293 Cells
	FAP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 87.2 kDa and the accession number is Q12884-1.
TMPY-04939	LAG-3 Protein, Human, Recombinant LAG-3,lymphocyte-activation gene 3,CD223	Human	HEK293 Cells
	LAG-3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.3 kDa and the accession number is P18627-1.
TMPY-04730	LAG-3 Protein, Human, Recombinant (His) LAG-3,lymphocyte-activation gene 3,CD223	Human	HEK293 Cells
	LAG-3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.6 kDa and the accession number is P18627-1.
TMPY-06074	B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His) V-set domain containing T cell activation inhibitor...	Cynomolgus,Rhesus	HEK293 Cells
	B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is A0A2K5U6P5-1.
TMPJ-00890	IL-13 Protein, Mouse, Recombinant (aa 26-131, His) Interleukin-13,T-Cell Activation Protein P600,白细胞介素...	Mouse	HEK293 Cells
	IL-13 Protein, Mouse, Recombinant (aa 26-131, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 15-30 KDa and the accession number is P20109.
TMPJ-00889	IL-13 Protein, Mouse, Recombinant (aa 22-131, His) T-Cell Activation Protein P600,IL-13,白细胞介素,Interleu...	Mouse	HEK293 Cells
	IL-13 Protein, Mouse, Recombinant (aa 22-131, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 14-30 KDa and the accession number is P20109.
TMPY-05322	B7-H4 Protein, Mouse, Recombinant (His) BC032925,B7h4,B7x,V-set domain containing T cell activat...	Mouse	HEK293 Cells
	B7-H4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is Q7TSP5.
TMPY-03524	B7-H4 Protein, Human, Recombinant (His) PRO1291,B7X,B7H4,B7-H4,VCTN1,B7S1,B7h.5,V-set domain contain...	Human	HEK293 Cells
	B7-H4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is Q7Z7D3-1.
TMPY-06525	FAP Protein, Human, Recombinant (aa 27-760, His) Fibroblast Activation Protein alpha,fibroblast ...	Human	Baculovirus Insect Cells
	FAP Protein, Human, Recombinant (aa 27-760, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 86.31 kDa and the accession number is Q12884-1.
TMPJ-00959	B7-2 Protein, Rabbit, Recombinant (His) CD86,T-lymphocyte activation antigen CD86,Activ...	Rabbit	HEK293 Cells
	B7-2 Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 38-70 KDa and the accession number is P42071.
TMPY-03759	LAG-3 Protein, Rat, Recombinant (His) lymphocyte-activation gene 3	Rat	HEK293 Cells
	LAG-3 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.1 kDa and the accession number is Q5BK54.
TMPJ-00958	B7-1 Protein, Rabbit, Recombinant (His) Activation B7-1 antigen,T-lymphocyte activation...	Rabbit	HEK293 Cells
	Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA4, constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. Although both CTLA-4 and CD28 can ...
TMPY-06915	FAP Protein, Human, Recombinant (His & Avi), Biotinylated FAPA,Fapalpha,Fibroblast Activation Protein α,Fapα,...	Human	HEK293 Cells
	FAP Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 88.23 kDa and the accession number is Q12884-1.
TMPJ-00632	B7-2 Protein, Cynomolgus, Recombinant (hFc) T-lymphocyte activation antigen CD86 isoform 1,...	Cynomolgus	HEK293 Cells
	B7-2 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 70-100 KDa and the accession number is G7NXR4.
TMPJ-00630	B7-1 Protein, Cynomolgus, Recombinant (hFc) B7,CD80,T-lymphocyte activation antigen CD80,Ac...	Cynomolgus	HEK293 Cells
	Cynomologous Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily.It is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells.CD80 plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA4, constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses. CD80 is mostly expressed on the ...
TMPJ-00641	B7-2 Protein, Rhesus macaque, Recombinant (His) Activation B7-2 antigen,T-lymphocyte activation...	Rhesus	HEK293 Cells
	B7-2 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 40-90 KDa and the accession number is H9ZFI8.
TMPY-03667	SLAM/CD150 Protein, Rat, Recombinant (His) signaling lymphocytic activation molecule family me...	Rat	HEK293 Cells
	SLAM/CD150 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession number is D3ZAD7.
TMPY-00627	SLAM/CD150 Protein, Rat, Recombinant (hFc) signaling lymphocytic activation molecule family me...	Rat	HEK293 Cells
	SLAM/CD150 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.3 kDa and the accession number is A6JG08.
TMPY-04731	LAG-3 Protein, Human, Recombinant (mFc) lymphocyte-activation gene 3,CD223,LAG-3	Human	HEK293 Cells
	LAG-3 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 72.6 kDa and the accession number is P18627-1.
TMPY-04528	LAG-3 Protein, Human, Recombinant (hFc) lymphocyte-activation gene 3,CD223,LAG-3	Human	HEK293 Cells
	LAG-3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 72.9 kDa and the accession number is P18627-1.
TMPY-05130	LAG-3 Protein, Human, Recombinant, Biotinylated lymphocyte-activation gene 3,CD223,LAG-3	Human	HEK293 Cells
	LAG-3 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.3 kDa and the accession number is P18627-1.
TMPY-06931	LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated lymphocyte-activation gene 3,CD223,LAG-3	Human	HEK293 Cells
	LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 74.73 kDa and the accession number is NP_002277.4.
TMPY-04611	LAG-3 Protein, Mouse, Recombinant (hFc) lymphocyte-activation gene 3,Ly66,LAG-3,CD223	Mouse	HEK293 Cells
	LAG-3 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 72.1 kDa and the accession number is Q61790.
TMPJ-00607	RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His) Receptor activator of nuclear factor κ-B ligand,Osteoprotege...	Mouse	HEK293 Cells
	RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 30-35 KDa and the accession number is BAA97257.1.
TMPJ-00556	B7-2 Protein, Human, Recombinant (His) CD86,T-Lymphocyte Activation Antigen CD86,Activ...	Human	HEK293 Cells
	B7-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 57-66 KDa and the accession number is AAH40261.1.
TMPY-02584	14-3-3 beta Protein, Cynomolgus, Recombinant tyrosine 3-monooxygenase/tryptophan 5-monooxygenase acti...	Cynomolgus	E. coli
	14-3-3 beta Protein, Cynomolgus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 27.8 kDa and the accession number is Q4R572-2.
TMPH-03275	Cytoglobin Protein, Rat, Recombinant (His & Myc) Stellate cell activation-associated protein,Stap,CY...	Rat	E. coli
	May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer. Plays a role in the development of liver fibrosis. Has a peroxidase activity.
TMPY-05746	LAG-3 Protein, Mouse, Recombinant lymphocyte-activation gene 3,LAG-3,Ly66,CD223	Mouse	HEK293 Cells
	LAG-3 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.25 kDa and the accession number is Q61790.
TMPY-04612	LAG-3 Protein, Mouse, Recombinant (His) LAG-3,Ly66,lymphocyte-activation gene 3,CD223	Mouse	HEK293 Cells
	LAG-3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.7 kDa and the accession number is Q61790.
TMPJ-00555	B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated Activation B7-2 Antigen,FUN-1,CTLA-4 Counter-Recept...	Human	HEK293 Cells
	B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 55-80 KDa and the accession number is AAH40261.1.
TMPY-02179	14-3-3 epsilon Protein, Mouse, Recombinant (GST) AU019196,tyrosine 3-monooxygenase/tryptophan 5-monooxygenase...	Mouse	E. coli
	14-3-3 epsilon Protein, Mouse, Recombinant (GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 56.1 kDa and the accession number is P62259.
TMPY-02378	14‑3‑3 theta/YWHAQ Protein, Human, Recombinant (GST) tyrosine 3-monooxygenase/tryptophan 5-monooxygenase acti...	Human	E. coli
	The recently identified 14-3-3 tau, whose corresponding gene name is YWHAQ, is in a hypoxia-treated human trophoblast cell line. YWHAQ may play a role in epigenetic regulation of placental genes in the onset of Preeclampsia (PE). Moreover, there was a closer relationship between blood pressure and methylation levels of the YWHAQ promoter.
TMPJ-01070	CD83 Protein, Human, Recombinant (hFc) hCD83,B-cell activation protein,CD_antigen,Cell sur...	Human	HEK293 Cells
	CD83 antigen is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. CD83 is expressed by activated lymphocytes, Langerhans cells and interdigitating reticulum cells. It contains one Ig-like V-type (immunoglobulin-like) domain. , the soluble CD83 has the opposite effect and has an immune inhibitory capacity. Due to its immune inhibitory function, CD83 may play a significant role in antigen presentation or the cellular interactions that follow lymp...
TMPH-00213	Disintegrin batroxostatin Protein, Bothrops atrox, Recombinant (His & Myc) Platelet aggregation activation inhibitor,Disintegr...	Bothrops atrox	E. coli
	Inhibits fibrinogen interaction with platelets. Acts by binding to the glycoprotein IIb-IIIa receptor (ITGA2B/ITGB3) on the platelet surface and inhibits aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Also inhibits T24 and SK-Mel-28 cell adhesion to fibronectin with IC(50) of 4.4 uM and 33 nM, respectively. Disintegrin batroxostatin Protein, Bothrops atrox, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted...
TMPJ-01248	Cytoglobin/CYGB Protein, Human, Recombinant (His) Stellate Cell Activation-Associated Protein,Cytoglo...	Human	E. coli
	Cytoglobin is a ubiquitously globin protein that belongs to the globin family. The highest expressed in heart, stomach, bladder and small intestine. CYGB acts a protector under conditions of oxidative stress. CYGB may be involved in intracellular oxygen storage or transfer, modulates oxygen and nitric oxide metabolism or scavenging free radicals within a cell.
TMPJ-00223	SLAMF1 Protein, Human, Recombinant (His & Avi), Biotinylated CDw150,CD150,SLAM,IPO-3,SLAMF1,Signaling Lymphocytic Act...	Human	HEK293 Cells
	SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.
TMPJ-01323	NTAL Protein, Human, Recombinant (His) Williams-Beuren Syndrome Chromosomal Region 5 P,Membrane-Ass...	Human	HEK293 Cells
	Linker for Activation of T-Cells Family Member 2 (LAT2) is a single-pass type III membrane protein. LAT2 is highly expressed in the spleen, peripheral blood lymphocytes, and germinal centers of lymph nodes. LAT2 is involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. It may also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. ...
TMPJ-01206	Sting Protein, Human, Recombinant (Sumo & His) TMEM173,Mediator of IRF3 activation,Stimulator of i...	Human	E. coli
	Stimulator of Interferon Gene(Sting,TMEM173) belongs to the TMEM173 family. STING is 379 amino acids (aa) in length. It contains an N-terminal cytoplasmic region (aa 1-20), four transmembrane segments (aa 21-173), and a C-terminal cytoplasmic domain (aa 174-379). It ubiquitously expressed in skin endothelial cells, alveolar type 2 pneumocytes, bronchial epithelium and alveolar macrophagesand. Its subunit structure associated with the MHC-II complex and Interacts with DDX58/RIG-I, MAVS and SSR2,...
TMPJ-01421	LAG-3 Protein, Cynomolgus, Recombinant (hFc) LAG-3,Protein FDC,Lymphocyte activation gene 3 prot...	Cynomolgus	HEK293 Cells
	LAG-3 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90 KDa and the accession number is XP_005570011.1.
TMPY-01016	SLAM/CD150 Protein, Human, Recombinant (His) CDw150,CD150,signaling lymphocytic activation molec...	Human	HEK293 Cells
	SLAM/CD150 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.8 kDa and the accession number is Q13291-1.
TMPY-02377	14-3-3 eta/YWHAH Protein, Human, Recombinant (GST) tyrosine 3-monooxygenase/tryptophan 5-monooxygenase acti...	Human	E. coli
	YWHAH, the gene encoding the 14-3-3eta isoform, is highly expressed in retinal ganglion cells (RGC). YWHAH is a positional and functional candidate gene for both schizophrenia and bipolar disorder (BP). It is located on chromosome 22q12.3, a region that has been implicated by linkage studies in both BP and schizophrenia.
TMPJ-00321	LAG-3 Protein, Human, Recombinant (His & Avi), Biotinylated Lymphocyte activation gene 3 protein,CD223,LAG-3,Pr...	Human	HEK293 Cells
	LAG-3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 60-70 KDa and the accession number is P18627.
TMPJ-00226	SLAMF1 Protein, Mouse, Recombinant (His) signaling lymphocytic activation molecule,SLAM fami...	Mouse	HEK293 Cells
	Signaling lymphocyte activation molecule (SLAM), is a self-ligand glycoprotein which exists not only found on the surface of activated and memory T cells, but also on the surface of activated B cells, dendritic cells, and macrophages. SLAM consists of a extracellular domain (ECD) with two Ig-like domains,transmembrane segment, and cytoplasmic domain with three immunoreceptor tyrosine switch motifs (ITSM). SLAM is thought to play an important role in adhesion between T cells and APCs and has been...
TMPH-02908	AICDA Protein, Mouse, Recombinant (His & Myc) Single-stranded DNA cytosine deaminase,Cytidine aminohydrola...	Mouse	E. coli
	Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation (SHM), gene conversion, and class-switch recombination (CSR) in B-lymphocytes by deaminating C to U during transcription of Ig-variable (V) and Ig-switch (S) region DNA. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation.
TMPY-01267	14-3-3 epsilon Protein, Human, Recombinant (GST) MDCR,MDS,HEL2,14-3-3E,tyrosine 3-monooxygenase/tryptophan 5-...	Human	E. coli
	14-3-3 epsilon Protein, Human, Recombinant (GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 56 kDa and the accession number is P62258-1.
TMPY-02658	B7-H4 Protein, Mouse, Recombinant (hFc) B7h4,BC032925,B7x,B7s1,V-set domain containing T cell ac...	Mouse	HEK293 Cells
	B7-H4 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.2 kDa and the accession number is Q7TSP5.
TMPY-01274	14-3-3 epsilon Protein, Human, Recombinant HEL2,MDCR,tyrosine 3-monooxygenase/tryptophan 5-monooxygenas...	Human	E. coli
	14-3-3 epsilon Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 29.4 kDa and the accession number is P62258-1.
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重组蛋白

FAP Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-04962

Species: Cynomolgus

Expression System: HEK293 Cells

LAG-3 Protein, Cynomolgus, Recombinant (74 Pro, His)

Cat.No: TMPY-05092

Species: Cynomolgus

Expression System: HEK293 Cells

FAP Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-04922

Species: Human

Expression System: HEK293 Cells

FAP Protein, Human, Recombinant (His)

Cat.No: TMPY-02154

Species: Human

Expression System: HEK293 Cells

LAG-3 Protein, Human, Recombinant

Cat.No: TMPY-04939

Species: Human

Expression System: HEK293 Cells

LAG-3 Protein, Human, Recombinant (His)

Cat.No: TMPY-04730

Species: Human

Expression System: HEK293 Cells

B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His)

Cat.No: TMPY-06074

Species: Cynomolgus,Rhesus

Expression System: HEK293 Cells

IL-13 Protein, Mouse, Recombinant (aa 26-131, His)

Cat.No: TMPJ-00890

Species: Mouse

Expression System: HEK293 Cells

IL-13 Protein, Mouse, Recombinant (aa 22-131, His)

Cat.No: TMPJ-00889

Species: Mouse

Expression System: HEK293 Cells

B7-H4 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-05322

Species: Mouse

Expression System: HEK293 Cells

B7-H4 Protein, Human, Recombinant (His)

Cat.No: TMPY-03524

Species: Human

Expression System: HEK293 Cells

FAP Protein, Human, Recombinant (aa 27-760, His)

Cat.No: TMPY-06525

Species: Human

Expression System: Baculovirus Insect Cells

B7-2 Protein, Rabbit, Recombinant (His)

Cat.No: TMPJ-00959

Species: Rabbit

Expression System: HEK293 Cells

LAG-3 Protein, Rat, Recombinant (His)

Cat.No: TMPY-03759

Species: Rat

Expression System: HEK293 Cells

B7-1 Protein, Rabbit, Recombinant (His)

Cat.No: TMPJ-00958

Species: Rabbit

Expression System: HEK293 Cells

FAP Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-06915

Species: Human

Expression System: HEK293 Cells

B7-2 Protein, Cynomolgus, Recombinant (hFc)

Cat.No: TMPJ-00632

Species: Cynomolgus

Expression System: HEK293 Cells

B7-1 Protein, Cynomolgus, Recombinant (hFc)

Cat.No: TMPJ-00630

Species: Cynomolgus

Expression System: HEK293 Cells

B7-2 Protein, Rhesus macaque, Recombinant (His)

Cat.No: TMPJ-00641

Species: Rhesus

Expression System: HEK293 Cells

SLAM/CD150 Protein, Rat, Recombinant (His)

Cat.No: TMPY-03667

Species: Rat

Expression System: HEK293 Cells

SLAM/CD150 Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-00627

Species: Rat

Expression System: HEK293 Cells

LAG-3 Protein, Human, Recombinant (mFc)

Cat.No: TMPY-04731

Species: Human

Expression System: HEK293 Cells

LAG-3 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04528

Species: Human

Expression System: HEK293 Cells

LAG-3 Protein, Human, Recombinant, Biotinylated

Cat.No: TMPY-05130

Species: Human

Expression System: HEK293 Cells

LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated

Cat.No: TMPY-06931

Species: Human

Expression System: HEK293 Cells

LAG-3 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-04611

Species: Mouse

Expression System: HEK293 Cells

RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00607

Species: Mouse

Expression System: HEK293 Cells

B7-2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00556

Species: Human

Expression System: HEK293 Cells

14-3-3 beta Protein, Cynomolgus, Recombinant

Cat.No: TMPY-02584

Species: Cynomolgus

Expression System: E. coli

Cytoglobin Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03275

Species: Rat

Expression System: E. coli

LAG-3 Protein, Mouse, Recombinant

Cat.No: TMPY-05746

Species: Mouse

Expression System: HEK293 Cells

LAG-3 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04612

Species: Mouse

Expression System: HEK293 Cells

B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated

Cat.No: TMPJ-00555

Species: Human

Expression System: HEK293 Cells

14-3-3 epsilon Protein, Mouse, Recombinant (GST)

Cat.No: TMPY-02179

Species: Mouse

Expression System: E. coli

14‑3‑3 theta/YWHAQ Protein, Human, Recombinant (GST)

Cat.No: TMPY-02378

Species: Human

Expression System: E. coli

CD83 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-01070

Species: Human

Expression System: HEK293 Cells

Disintegrin batroxostatin Protein, Bothrops atrox, Recombinant (His & Myc)

Cat.No: TMPH-00213

Species: Bothrops atrox

Expression System: E. coli

Cytoglobin/CYGB Protein, Human, Recombinant (His)

Cat.No: TMPJ-01248

Species: Human

Expression System: E. coli

SLAMF1 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPJ-00223

Species: Human

Expression System: HEK293 Cells

NTAL Protein, Human, Recombinant (His)

Cat.No: TMPJ-01323

Species: Human

Expression System: HEK293 Cells

Sting Protein, Human, Recombinant (Sumo & His)

Cat.No: TMPJ-01206

Species: Human

Expression System: E. coli

LAG-3 Protein, Cynomolgus, Recombinant (hFc)

Cat.No: TMPJ-01421

Species: Cynomolgus

Expression System: HEK293 Cells

SLAM/CD150 Protein, Human, Recombinant (His)

Cat.No: TMPY-01016

Species: Human

Expression System: HEK293 Cells

14-3-3 eta/YWHAH Protein, Human, Recombinant (GST)

Cat.No: TMPY-02377

Species: Human

Expression System: E. coli

LAG-3 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPJ-00321

Species: Human

Expression System: HEK293 Cells

SLAMF1 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00226

Species: Mouse

Expression System: HEK293 Cells

AICDA Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02908

Species: Mouse

Expression System: E. coli

14-3-3 epsilon Protein, Human, Recombinant (GST)

Cat.No: TMPY-01267

Species: Human

Expression System: E. coli

B7-H4 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02658

Species: Mouse

Expression System: HEK293 Cells

14-3-3 epsilon Protein, Human, Recombinant

Cat.No: TMPY-01274

Species: Human

Expression System: E. coli

--------- 更多 ---------

Cat. No.	Product Name	Target	Signaling Pathways
T14687	Deucravacitinib BMS-986165	Tyrosine Kinases; JAK; IFNAR; Interleukin	Angiogenesis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
	Deucravacitinib (BMS-986165) 是一种高选择性、口服生物可利用的变构 TYK2 抑制剂，用于治疗自身免疫性疾病。它通过稳定调节 JH2 结构域来阻断受体介导的 Tyk2 激活，可抑制IL-12/23和 I 型IFN 途径。它选择性结合 TYK2 假激酶 (JH2) 结构域，IC50为1.0 nM。
T11250	Ezetimibe-d4 SCH 58235 D4	Others	Others
	Ezetimibe D4, a deuterium-labeled variant of Ezetimibe, functions as an inhibitor of Niemann-Pick C1-like1 (NPC1L1) and is recognized for its potent activation of Nrf2.
TMIH-0065	Acalabrutinib-d4
	Acalabrutinib-d4 是 Acalabrutinib 的氘代化合物。Acalabrutinib 的 CAS 号为 1420477-60-6。Acalabrutinib 是一种不可逆的、高效的、具有口服活性、选择性的第二代BTK抑制剂。它与 BTK 的 ATP 结合口袋中的 Cys481 共价结合。它在慢性淋巴细胞性白血病 (CLL) 小鼠模型中显示出强大的靶向作用和功效。
TMID-0087	Azathioprine-d3
	Azathioprine-d3 是 Azathioprine 的氘代化合物。Azathioprine 的 CAS 号为 446-86-6。Azathioprine是一种免疫抑制剂。
T35697	Lauric Acid-13C
	Lauric acid-13C is intended for use as an internal standard for the quantification of lauric acid by GC- or LC-MS. Lauric acid is a medium-chain saturated fatty acid. It has been found at high levels in coconut oil.1Lauric acid induces the activation of NF-κB and the expression of COX-2, inducible nitric oxide synthase (iNOS), and IL-1α in RAW 264.7 cells when used at a concentration of 25 μM.2
TMIJ-0108	rac-Hesperetin-13C-d3 rac-Diosmin EP Impurity G-13C-d3
	rac-Hesperetin-13C-d3 是 rac-Hesperetin 的 13C 和氘代化合物。rac-Hesperetin 的 CAS 号为 69097-99-0。
TMIJ-0231	Hydroxy Pentoxifylline-d6 rac-Lisofylline-d6
	Hydroxy Pentoxifylline-d6 是 Hydroxy Pentoxifylline 的氘代化合物。Hydroxy Pentoxifylline 的 CAS 号为 6493-06-7。(±)-Lisofylline 是一种对映异构体特异性、烷基取代的甲基黄嘌呤，在下调白细胞活化方面具有特异性和有效的活性。它是一种抗炎剂。
TMIH-0181	Demethoxy Curcumin-d4
	Demethoxy Curcumin-d4 是 Demethoxy Curcumin 的氘代化合物。Demethoxy Curcumin 的 CAS 号为 22608-11-3。Demethoxycurcumin是姜黄素的主要活性成分，有抗炎和抗癌作用。
TMIJ-0139	Ticagrelor-d7
	Ticagrelor-d7 是 Ticagrelor 的氘代化合物。Ticagrelor 的 CAS 号为 274693-27-5。Ticagrelor (AZD6140) 是可逆的，可口服的P2Y12受体拮抗剂，可抑制血小板聚集。
T71303	Flufenamic Acid-d4
	Flufenamic acid-d4 is intended for use as an internal standard for the quantification of flufenamic acid by GC- or LC-MS. Flufenamic acid is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 3 and 9.3 µM for human COX-1 and COX-2, respectively). Flufenamic acid inhibits TNF-α-induced increases in COX-2 levels and NF-κB activation in HT-29 colon cancer cells in a concentration-dependent manner. It inhibits calcium influx induced by fMLP or A23187 in human polymorphonuclear...

同位素标记化合物

Deucravacitinib

Cat.No: T14687

Synonym: BMS-986165

Target: Tyrosine Kinases, JAK, IFNAR, Interleukin

Cat.No: T11250

Synonym: SCH 58235 D4

Target: Others

Acalabrutinib-d4

Cat.No: TMIH-0065

Azathioprine-d3

Cat.No: TMID-0087

Lauric Acid-13C

Cat.No: T35697

rac-Hesperetin-13C-d3

Cat.No: TMIJ-0108

Synonym: rac-Diosmin EP Impurity G-13C-d3

Hydroxy Pentoxifylline-d6

Cat.No: TMIJ-0231

Synonym: rac-Lisofylline-d6

Demethoxy Curcumin-d4

Cat.No: TMIH-0181

Cat.No: TMIJ-0139

Flufenamic Acid-d4

Cat.No: T71303

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