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2-oxo Clopidogrel is an intermediary metabolite of clopidogrel . Clopidogrel is a prodrug that is converted to its active metabolite via two sequential oxidative steps. The first step leads to formation of 2-oxo clopidogrel, followed by conversion to the active metabolite, which binds specifically and irreversibly to the platelet P2Y12 purinergic receptor, inhibiting ADP-mediated platelet activation and aggregation.
2-oxo Clopidogrel is an intermediary metabolite of clopidogrel . Clopidogrel is a prodrug that is converted to its active metabolite via two sequential oxidative steps. The first step leads to formation of 2-oxo clopidogrel, followed by conversion to the active metabolite, which binds specifically and irreversibly to the platelet P2Y12 purinergic receptor, inhibiting ADP-mediated platelet activation and aggregation.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
500 μg | ¥ 857 | 35日内发货 | |
1 mg | ¥ 1,610 | 35日内发货 | |
5 mg | ¥ 6,230 | 35日内发货 |
产品描述 | 2-oxo Clopidogrel is an intermediary metabolite of clopidogrel . Clopidogrel is a prodrug that is converted to its active metabolite via two sequential oxidative steps. The first step leads to formation of 2-oxo clopidogrel, followed by conversion to the active metabolite, which binds specifically and irreversibly to the platelet P2Y12 purinergic receptor, inhibiting ADP-mediated platelet activation and aggregation. |
分子量 | 337.82 |
分子式 | C16H16ClNO3S |
CAS No. | 109904-27-0 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度信息 | Ethanol: 5 mg/mL (14.8 mM), Sonication is recommended. DMSO: 20 mg/mL (59.2 mM), Sonication is recommended. DMF:PBS (pH 7.2) (1:20): 0.04 mg/mL (0.12 mM), Sonication is recommended. DMF: 25 mg/mL (74 mM), Sonication is recommended. |
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