N-Hydroxysuccinimide (HOSu; 1-Hydroxy-2,5-pyrrolidinedione) serves as an activated ester widely employed in bioconjugation technologies. It is utilized for protein labeling with fluorescent dyes and enzymes, the development of chromatography supports, beads, nanoparticles, and microarrays, surface activation of glass slides, and the chemical synthesis of peptides [1].