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BPK-21 is an active acrylamide compound that effectively suppresses T cell activation by blocking the function of ERCC3, a helicase enzyme. BPK-21 specifically targets C342 within the ERCC3 helicase.
BPK-21 is an active acrylamide compound that effectively suppresses T cell activation by blocking the function of ERCC3, a helicase enzyme. BPK-21 specifically targets C342 within the ERCC3 helicase.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
2 mg | ¥ 1,600 | 5日内发货 | |
5 mg | ¥ 2,710 | 5日内发货 | |
1 mL x 10 mM (in DMSO) | ¥ 3,250 | 5日内发货 |
产品描述 | BPK-21 is an active acrylamide compound that effectively suppresses T cell activation by blocking the function of ERCC3, a helicase enzyme. BPK-21 specifically targets C342 within the ERCC3 helicase. |
体外活性 | BPK-21 (20 μM) significantly impairs T cellactivation[1]. BPK-21 likely suppresses T cell activation through blockadeof ERCC3 function, which may in turn act downstream or sepa-rately from pathways involved in NFAT and NF-kB activation[1]. |
分子量 | 466.28 |
分子式 | C23H16Cl2F3NO2 |
CAS No. | 2305052-77-9 |
密度 | 1.365 g/cm3 (Predicted) |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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