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2-Methylbutyrylcarnitine (chloride) 作为一种支链酰基肉碱,是肠道微生物代谢的产物。它通过结合血小板中的整合素α2β1,不仅促进细胞质磷脂酶 A2 (cPLA2) 的活化,而且增强了血小板的过度反应性。此外,实验表明,2-Methylbutyrylcarnitine (chloride) 能显著提升小鼠血小板的超反应性和血栓形成能力。
2-Methylbutyrylcarnitine (chloride) 作为一种支链酰基肉碱,是肠道微生物代谢的产物。它通过结合血小板中的整合素α2β1,不仅促进细胞质磷脂酶 A2 (cPLA2) 的活化,而且增强了血小板的过度反应性。此外,实验表明,2-Methylbutyrylcarnitine (chloride) 能显著提升小鼠血小板的超反应性和血栓形成能力。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 期货 | |
50 mg | 询价 | 期货 |
产品描述 | 2-Methylbutyrylcarnitine (chloride) acts as a gut microbial metabolite that targets integrin α2β1 on platelets, facilitating the activation of cytosolic phospholipase A2 (cPLA2) and enhancing platelet hyperresponsiveness. This compound further augments platelet hyperreactivity and promotes thrombus formation in mice. It is also characterized as a branched-chain acylcarnitine. |
分子量 | 281.78 |
分子式 | C12H24ClNO4 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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