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8-Br-PET-cGMP 作为一种cGMP依赖性蛋白激酶I型(cGKI)的激动剂,其激活作用是通过结合到cGKI的调节域,从而促进其二聚化和催化活性的激活.该化合物广泛应用于探讨cGMP信号通路在细胞生长、血管舒张及平滑肌细胞功能等生物过程中的角色.
8-Br-PET-cGMP 作为一种cGMP依赖性蛋白激酶I型(cGKI)的激动剂,其激活作用是通过结合到cGKI的调节域,从而促进其二聚化和催化活性的激活.该化合物广泛应用于探讨cGMP信号通路在细胞生长、血管舒张及平滑肌细胞功能等生物过程中的角色.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 10-14周 | |
50 mg | 询价 | 10-14周 |
产品描述 | 8-Br-PET-cGMP is an agonist of type I cyclic GMP-dependent protein kinase (cGKI), which promotes the dimerization and activation of the catalytic activity of cGKI by binding to its regulatory domain. This compound is utilized to investigate the role of the cGMP signaling pathway in cell growth, vasodilation, and smooth muscle cell functions. |
分子量 | 524.22 |
分子式 | C18H15BrN5O7P |
CAS No. | 144510-04-3 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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