7745
1000+
88
695
29
Cat. No. | Product Name | ||
---|---|---|---|
L4800 | 血管生成库 | 1353 compounds | |
1353 个高潜力的抑制或促进血管生成的小分子集合,可用于药物靶点开发、血管生成机理研究的高通量筛选,高内涵筛选; | |||
L9230 | ReFRAME 相关化合物库 | 3210 compounds | |
3210 化合物的独特集合,可用于高通量筛选和高内涵筛选 | |||
L2690 | 疼痛相关化合物库 | 2739 compounds | |
2739种疼痛相关化合物的独特集合,可用于高通量筛选和高内涵筛选 | |||
L9410 | 共价抑制剂库 | 1920 compounds | |
1920 种小分子的独特集合,包含已发现的共价抑制剂以及包含某些共价反应基团常见弹头的分子,如氯乙酰基,2-氯丙酰基,丙烯酰基,1-丙-2-炔基,1-丁-2-炔基,酮羰基,二硫键等,可以用于共价抑制剂药物研发; | |||
L2530 | 小鼠代谢化合物库 | 218 compounds | |
218 种小鼠代谢化合物的集合,可用于高通量筛选和高内涵筛选; | |||
L3900 | DNA 损伤和修复分子库 | 910 compounds | |
910 个与 DNA 损伤和修复紧密相关的化合物集合,是高通量筛选,高内涵筛选的良好载体; | |||
L2501 | 人内源代谢化合物库 Plus | 1283 compounds | |
1283种内源性生物活性化合物的独特集合,用于高通量、高内涵筛选。 | |||
L8100 | 细胞周期化合物库 | 677 compounds | |
677 种细胞周期相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L6600 | 胃肠炎天然产物库 | 219 compounds | |
219 种胃肠炎相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L2620 | 神经退行性疾病化合物库 | 2154 compounds | |
2154 种与神经退行性疾病相关的化合物,可用于高通量和高内涵筛选; | |||
L3500 | 组蛋白修饰化合物库 | 469 compounds | |
469 个组蛋白修饰相关的小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L2200 | 酪氨酸激酶分子库 | 1016 compounds | |
1016 种酪氨酸激酶抑制剂的独特集合,可用于高通量筛选和高内涵筛选; | |||
L8710 | 铜死亡化合物库 | 400 compounds | |
TargetMol 铜死亡化合物库集合了 400 种与铜死亡相关的化合物,可以用于铜死亡机制及相关疾病研究 | |||
L4660 | 神经疾病库Plus | 1246 compounds | |
1246 种神经系统相关、结构新颖的化合物; | |||
L5400 | 抗心血管疾病化合物库 | 1408 compounds | |
1408 种心血管疾病相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L2520 | 糖代谢化合物库 | 702 compounds | |
702 种糖代谢相关的化合物,可用于高通量和高内涵筛选; | |||
L5200 | 抗代谢疾病化合物库 | 1544 compounds | |
1544 个代谢疾病相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L2193 | 抗肝癌化合物库 | 1787 compounds | |
1787 种与肝癌相关的化合物,可以用于抗肝癌药物研发和药理研究; | |||
L4710 | 非甾体类抗炎化合物库 | 530 compounds | |
530 种非甾体类的抗炎相关化合物,可用于高通量和高内涵筛选; | |||
L3980 | DNA损伤/修复库Plus | 667 compounds | |
667 种 DNA 损伤/修复靶向、结构新颖的化合物; | |||
L9240 | 农药化合物库 | 270 compounds | |
270种农药相关化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L2521 | 糖酵解化合物库 | 555 compounds | |
555 种糖酵解相关的活性化合物,可用于高通量和高内涵筛选 | |||
L2510 | 脂代谢化合物库 | 492 compounds | |
492 个脂代谢相关的化合物集合,可用于高通量和高内涵筛选; | |||
L3510 | 甲基化化合物库 | 128 compounds | |
128 种甲基化相关的化合物,可以用于高通量和高内涵筛选; | |||
L2560 | 代谢化合物库 | 2320 compounds | |
2320 种代谢途径相关的化合物,可用于高通量和高内涵筛选。 | |||
L7500 | 凝血与抗凝化合物库 | 144 compounds | |
144 个化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L2130 | 抗癌细胞代谢库 | 1268 compounds | |
1268 种癌细胞代谢相关的生物活性小分子化合物的特有集合,用于肿瘤相关的研究以及抗肿瘤药物的筛选,用于高通量、高内涵筛选; | |||
L9400 | PPI抑制剂库 | 485 compounds | |
485 种已知活性的 PPI 相关的抑制剂,可用于高通量、高内涵筛选; | |||
L9700 | 内质网应激化合物库 | 193 compounds | |
193 个内质网应激相关的化合物集合,可用于高通量和高内涵筛选; | |||
L2195 | 抗前列腺癌化合物库 | 2070 compounds | |
2070 种与前列腺癌相关的化合物,可以用于高通量和高内涵筛选 | |||
L9860 | 抗抑郁症化合物库 | 1163 compounds | |
1163 种与抑郁症相关的化合物,可以用于高通量和高内涵筛选 | |||
L2194 | 抗结直肠癌化合物库 | 1545 compounds | |
1545 种与结直肠癌相关的化合物,可以用于高通量和高内涵筛选; | |||
L1400 | MAPK 抑制剂库 | 365 compounds | |
365 种与MAPK 信号通路相关的生物活性小分子化合物的特有集合,可用于高通量筛选和高内涵筛选; | |||
L2191 | 抗乳腺癌化合物库 | 1939 compounds | |
1939 种与乳腺癌相关的化合物,可以用于抗乳腺癌药物研发和药理研究; | |||
L1600 | 激酶抑制剂库 | 2720 compounds | |
2720 种激酶抑制剂/调节剂的独特集合,用于特定靶向激酶,可用于高通量筛选和高内涵筛选; | |||
L1200 | 表观遗传库 | 953 compounds | |
953 种表观遗传学研究相关的生物活性小分子的特有集合,用于表观遗传学研究及其相关的检测和高通量、高内涵筛选; | |||
L2192 | 抗胰腺癌化合物库 | 2238 compounds | |
2238 种与胰腺癌相关的化合物,可以用于高通量和高内涵筛选; | |||
L1610 | FDA 上市激酶抑制剂库 | 263 compounds | |
263种靶向激酶的上市药物集合,用于特定靶向激酶,可用于高通量筛选和高内涵筛选; | |||
L8700 | 铁死亡化合物库 | 779 compounds | |
779 种与铁死亡通路相关的化合物,可用于高通量和高内涵筛选; | |||
L7000 | 活性脂质化合物库 | 385 compounds | |
385 种生物活性小分子化合物,用于高通量、高内涵筛选; | |||
L8600 | 泛素化化合物库 | 210 compounds | |
210 种泛素化相关的小分子,用于高通量和高内涵筛选; | |||
L6010 | 天然产物库 | 3840 compounds | |
3840 种天然产物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L2540 | 肠道微生物代谢化合物库 | 614 compounds | |
614 种肠道微生物代谢物的集合,可以用于高通量和高内涵筛选; | |||
L8110 | 细胞重编程化合物库 | 1813 compounds | |
1813 种重编程信号通路相关的生物活性小分子化合物的特有集合,可用于高通量、高内涵筛选 | |||
L2000 | 抑制剂库 | 8328 compounds | |
8328 个小分子抑制剂的独特集合,主要用于细胞信号研究、新药筛选、高通量筛选和高内涵筛选; | |||
L8400 | 血液病分子库 | 514 compounds | |
514 种造血系统疾病相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L4400 | 抗生素库 | 692 compounds | |
692 个具有抗菌活性化合物的独特集合,是医药研究的优良工具库和药物筛选的有效载体; | |||
L1510 | 核受体化合物库 | 531 compounds | |
531 个核受体作用化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L9000 | 细胞凋亡化合物库 | 1760 compounds | |
1760 种与凋亡相关的生物活性小分子化合物的特有集合,多用于研究肿瘤发生发展机制和抗癌药物筛选等。可用于高通量筛选和高内涵筛选; | |||
L7110 | 抗高血压化合物库 | 678 compounds | |
678 种高血压相关的小分子,用于高通量和高内涵筛选; | |||
L8400 | 血液病分子库 | 514 compounds | |
514 种造血系统疾病相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L9000 | 细胞凋亡化合物库 | 1760 compounds | |
1760 种与凋亡相关的生物活性小分子化合物的特有集合,多用于研究肿瘤发生发展机制和抗癌药物筛选等。可用于高通量筛选和高内涵筛选; | |||
L9810 | 抗纤维化化合物库 | 1180 compounds | |
1180 种潜在的抗纤维化分子,是研究纤维化的有效工具,可以用于高通量筛选和高内涵筛选; | |||
L9610 | 环肽库 | 80 compounds | |
80 种环肽分子,可用于高通量和高内涵筛选; | |||
L1710 | 抗COVID-19化合物库 | 1133 compounds | |
1133 种对SARS-CoV-2有抑制作用或潜在抑制作用的化合物集合,可用于高通量和高内涵筛选; | |||
L6030 | 天然产物衍生物虚筛化合物库 | 163000 compounds | |
16.3万种天然产物衍生物,并且在持续增加中; | |||
L1310 | 细胞骨架化合物库 | 759 compounds | |
759 种细胞骨架相关的化合物,可以用于高通量和高内涵筛选; | |||
L2150 | 抗癌药物库 | 3080 compounds | |
3080 个具有抗癌活性小分子的独特集合,生物活性已经临床前实验证实,可用于高通量、高内涵筛选; | |||
L8720 | 细胞焦亡化合物库 | 1066 compounds | |
1066 种细胞焦亡相关的化合物,可以用于细胞焦亡相关研究。 | |||
L2160 | 抗癌活性化合物库 | 3188 compounds | |
3188 种具有抗肿瘤活性的化合物的特有集合,用于高通量、高内涵筛选; | |||
L3600 | 细胞因子抑制剂库 | 604 compounds | |
604 个与细胞因子紧密相关的化合物集合,是高通量、高内涵筛选的良好载体; | |||
L2630 | 神经元分化化合物库 | 672 compounds | |
672 种与神经元分化相关的化合物,可以用于神经系统疾病药物研发 | |||
L9420 | 外泌体相关化合物库 | 76 compounds | |
76 种外泌体相关的化合物,可以用于高通量和高内涵筛选; | |||
L8500 | HIF-1化合物库 | 1336 compounds | |
1336 个HIF-1相关小分子的独特集合,可用于缺血性疾病、癌症等相关领域的药物开发和药理研究; | |||
L2100 | 抗癌化合物库 | 7234 compounds | |
7234 种肿瘤相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L6300 | 药食同源库 | 1290 compounds | |
1290 个药食同源化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L3700 | JAK-STAT 化合物库 | 252 compounds | |
252 个 JAK/STAT 靶点相关的小分子化合物的独特集合,用于高通量、高内涵筛选; | |||
L1120 | AMPK靶向分子库 | 80 compounds | |
80 个靶向AMPK 的分子集合,可用于高通量和高内涵筛选; | |||
L4100 | TGF-β/Smad靶点化合物库 | 184 compounds | |
184 个 TGF-β/Smad 靶点相关的小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L5900 | 血脑屏障通透化合物库 | 509 compounds | |
509 个 CNS-Penetrant 生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L8200 | 抗衰老化合物库 | 3279 compounds | |
3279 个抗衰老化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L2180 | 抗肿瘤库Plus | 1468 compounds | |
1468 种抗肿瘤相关、结构新颖的化合物; | |||
L8000 | 干细胞分化化合物库 | 1197 compounds | |
1197 种干细胞分化信号通路相关的生物活性小分子化合物的特有集合,可用于高通量、高内涵筛选; | |||
L1300 | PI3K/Akt/mTOR 化合物库 | 420 compounds | |
420 种与PI3K/Akt/mTOR 相关的生物活性小分子化合物的特有集合,用于PI3K/Akt/mTOR 相关研究以及高通量、高内涵筛选; | |||
L1110 | 微管靶向化合物库 | 142 compounds | |
142 种靶向微管的分子集合,用于高通量筛选和高内涵筛选; | |||
L1900 | 抗糖尿病库 | 683 compounds | |
683 种生物活性小分子化合物; | |||
L4300 | Wnt/Hedgehog/Notch 通路化合物库 | 237 compounds | |
237 个Wnt & Hedgehog & Notch 靶点相关的生物活性小分子化合物的特有集合,用于相关通路的研究及药物的筛选,可用于高通量、高内涵筛选。 | |||
L6740 | 抗结直肠癌中药单体化合物库 | 382 compounds | |
382 种抗结直肠癌相关的中药单体集合,是药物开发、药理研究的有效工具; | |||
L9600 | 多肽分子库 | 791 compounds | |
791 种多肽类分子,可用于多肽药物开发及信号转导通路和作用机制研究; | |||
L9830 | 抗帕金森病化合物库 | 857 compounds | |
857 种帕金森病相关的化合物集合,可用于高通量和高内涵筛选; | |||
L5300 | 线粒体靶向库 | 812 compounds | |
812 种具有潜在或确定线粒体靶向活性的化合物,以促进针对线粒体的药物研究; | |||
L7100 | 抗肥胖化合物库 | 2247 compounds | |
2247 个抗肥胖化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L6810 | 中药单体化合物库 | 2755 compounds | |
2755 种中药来源的单体化合物,是药物开发、药理研究等领域的有力工具; | |||
L6210 | 藏药化合物库 | 747 compounds | |
747 种藏药来源的天然产物分子集合,可以用于高通量和高内涵筛选; | |||
L2300 | 离子通道库 | 931 compounds | |
931 种与离子通道相关的生物活性小分子化合物的特有集合,用于离子通道相关的疾病和药物研究,可用于高通量筛选和高内涵筛选; | |||
L9840 | 抗阿尔茨海默症化合物库 | 986 compounds | |
986 种阿尔茨海默症相关的化合物集合,可用于高通量和高内涵筛选; | |||
L2550 | 谷氨酰胺代谢化合物库 | 565 compounds | |
565 种谷氨酰胺代谢相关的分子,可以用于高通量和高内涵筛选; | |||
DO1200 | 药物靶点库 | 53200 compounds | |
数量多,含53200种小分子化合物,是高通量筛选的有力工具; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7631L |
Eledoisin Related Peptide 2TFA
Eledoisin Related Peptide 2TFA(2990-43-4(free base)) |
Neurokinin receptor | GPCR/G Protein; Neuroscience |
Eledoisin Related Peptide 2TFA (Eledoisin Related Peptide 2TFA (2990-43-4(free base))) 是一种速激肽受体配体。 | |||
T0547 |
FlutaMide Related CoMpound B
|
Others | Others |
FlutaMide Related CoMpound B 用作医药中间体。 | |||
TP2310 |
Autocamtide-2-related inhibitory peptide
|
CaMK; Autophagy | Autophagy; Neuroscience |
Autocamtide-2-related inhibitory peptide 是一种高度特异性和有效的 CaMKII 抑制剂,IC50 为 40 nM。 | |||
T0535 |
Memantine Related Compound B
美金刚杂质B,3,5-Dimethyl-1-adamantanol |
Others | Others |
Memantine Related Compound B (3,5-Dimethyl-1-adamantanol) 是Memantine 的杂质。 | |||
T7631 |
Eledoisin Related Peptide
Eledoisin RP,Eledoisin-Related Peptide,Eledoisin Related Peptide(2TFA) |
Neurokinin receptor | GPCR/G Protein; Neuroscience |
Eledoisin Related Peptide (Eledoisin RP) 是一种速激肽受体配体,是物质P 的类似物,刺激神经元并触发行为反应。 | |||
T36483 |
Urotensin II-related peptide
|
||
Urotensin II-related peptide 是人尾加压素 II 类似物。Urotensin II-related peptide 与 UT 受体具有高亲和力。 | |||
TP1921L1 |
Autocamtide-2-related inhibitory peptide, myristoylated acetate(201422-04-0 free base)
|
CaMK; Autophagy | Autophagy; Neuroscience |
Autocamtide-2-related inhibitory peptide, myristoylated acetate 是CaM 激酶II 抑制剂;是 Autocamtide-2相关抑制肽的增强细胞渗透性衍生物。 | |||
T3971 |
CASIN
Pirl1-related Compound 2 |
CDK; STAT; Ras | Cell Cycle/Checkpoint; GPCR/G Protein; JAK/STAT signaling; MAPK; Stem Cells |
CASIN (Pirl1-related Compound 2) 是选择性GTPase Cdc42抑制剂,IC50值是 2 uM。 | |||
TP2393 |
Neurotensin-related hexapeptide
Lant-6 |
||
Neurotensin-related hexapeptide exists in retinal ganglion cells and in their central projections in pigeons and may be utilized as a neuroactive substance by the central terminals of numerous retinal ganglion cells in birds. | |||
TP1743 |
MPG, HIV related
|
||
MPG, a 27-amino acid peptide compound, is derived from the fusion peptide domain of HIV-1 gp41 and the nuclear localisation sequence of SV40 large T antigen. As a potent delivery agent, MPG enables efficient and widespread transport of nucleic acids and oligonucleotides into cultured cells. | |||
T36428 |
PACAP-related Peptide (human) (trifluoroacetate salt)
|
PACAP | GPCR/G Protein |
PACAP-related peptide (PRP) is an endogenous 29-amino acid peptide that belongs to the secretin/glucagon superfamily of peptides, which includes secretin , glucagon , glucagon-like peptide-1 , GLP-2 , and pituitary adenylate cyclase-activating polypeptide . It is expressed in normal human pancreas and adrenal gland tissue and in some tumors that produce vasoactive intestinal peptide (VIP). PRP (1-29) is secreted by CHO-K1 cells that express human recombinant preproPACAP. | |||
TP1216 |
CaM kinase II inhibitor TFA salt
Autocamtide-2-related inhibitory peptide (TFA) |
CaMK | Neuroscience |
CaM kinase II inhibitor TFA salt (Autocamtide-2-related inhibitory peptide(TFA)) 是一种高度特异性和有效的 CaMKII 抑制剂,IC50 为 40 nM。 | |||
T37435 | PACAP-related Peptide (rat) (trifluoroacetate salt) | PACAP | GPCR/G Protein |
PACAP-related peptide (PRP) is an endogenous 29-amino acid peptide that belongs to the secretin/glucagon superfamily of peptides, which includes secretin , glucagon , glucagon-like peptide-1 , GLP-2 , and pituitary adenylate cyclase-activating polypeptide . It is expressed in rat hypothalamus as well as within the nerves of the median eminence, the anterior pituitary, bed nucleus of the stria terminalis, cerebellum, cerebral cortex, and amygdala. PRP is also expressed in vaginal, uterine cervica... | |||
TP1200 |
CGRP (83-119), rat TFA
Calcitonin Gene Related Peptide(83-119), rat TFA |
Others | Others |
CGRP (83-119), rat TFA (Calcitonin Gene Related Peptide(83-119), rat TFA) 是一种由 37 个氨基酸组成的神经肽降钙素家族,通过降钙素受体样受体起作用。 | |||
T27635 |
Isoxepac
伊索克酸,Olopatadine USP Related Compound C |
Others | Others |
Isoxepac (Olopatadine USP Related Compound C) 是非甾体抗炎剂,显示出抗炎、镇痛和解热活性,已在多种动物模型中进行了相关研究。 | |||
T30786 |
Cefepime related compound E
Cefepime impurity E |
Others | Others |
Cefepime related compound E 是一种 Cefepime 的杂质,可用于生命科学领域相关实验。 | |||
T35010 |
Valacyclovir Related Compound D
N-Ethyl valacyclovir |
Others | Others |
Valacyclovir Related Compound D is a bioactive chemical. | |||
T20683 |
Letrozole related compound B
Letrozole specified impurity A |
Others | Others |
Letrozole related compound B is an impurity of aromatase inhibitor. | |||
T20396 |
Levadopa Related Compound A
6-Hydroxydopa, L-,L-Hydroxydopa |
Others | Others |
Levadopa Related Compound A is the 6-hydroxy derivative of the amino acid L-DOPA with neurotoxic properties. Exogenously administered 6-Hydroxy-L-DOPA is biotransformed by an amino acid decarboxylase to the highly potent and catecholamine-selective neurot | |||
TP1850 |
PACAP-Related Peptide (PRP), human
|
||
PACAP-Related Peptide (PRP), human,a 29 amino-acid region of the PACAP precursor protein, is synthesized in quantities sufficient for biological and structural studies. | |||
T1734 |
Rabeprazole Sulfide
雷贝拉唑相关物质E,Rabeprazole Related Compound E |
Proton pump; Antibacterial | Membrane transporter/Ion channel; Microbiology/Virology |
Rabeprazole Sulfide (Rabeprazole Related Compound E) 是 Rabeprazole 的活性代谢产物。Rabeprazole 是一种质子泵抑制剂类的抗溃疡药物,有效抑制幽门螺旋杆菌的活性,可通过与胃壁细胞中的(H+/K+)-ATPase 相互作用来抑制胃酸分泌,可研究各种消化系统疾病。 | |||
T39311 |
Tyrosinase-related Protein 2 (TRP-2) (181-188)
|
||
Tyrosinase-related Protein 2 (TRP-2) (181-188) is a peptide derived from the tyrosinase-related protein 2 (TRP-2), specifically corresponding to residues 180-188. It is the primary epitope within TRP-2 that is recognized by anti-B16 CTLs. Moreover, It is a peptide that conforms to the binding motif of the MHC class I H2-Kb. | |||
T125846 |
Clopidogrel Related Compound B
|
Others | Others |
Clopidogrel Related Compound B 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125846,CAS号为 144750-52-7。 | |||
T80764 |
Xenopsin-Related Peptide 2
XP-2 |
||
Xenopsin-Related Peptide 2 (XP-2),作为Xenopsin在鸟类中的对应物,具有诱导分离大鼠肥大细胞释放组胺的能力,其效力与合成Bradykinin相媲美。 | |||
TP2215 |
Agouti-related Protein (AGRP) (25-82), human
|
Others | Others |
Agouti-related peptide (AgRP) is a neuropeptide produced in the brain by the AgRP/NPY neuron. It is only synthesized in NPY containing cell bodies located in the ventromedial part of the arcuate nucleus in the hypothalamus. The appetite-stimulating effect | |||
T125853 |
Clopidogrel Related Compound A
|
Others | Others |
Clopidogrel Related Compound A 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125853,CAS号为 144457-28-3。 | |||
T124814 |
Barbaloin-related compound B
|
Others | Others |
Barbaloin-related compound B 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124814。 | |||
T76195 |
Stresscopin-related peptide (human)
|
||
Stresscopin-related peptide (human) 是 2 型 CRH 受体的特异性配体。Stresscopin-related peptide (human) 抑制食物摄入,延迟胃排空,并减少热引起的水肿。Stresscopin-related peptide (human) 在应激后维持体内平衡,可用于应激相关疾病的研究。 | |||
T67035 |
Imiquimod Related Compound A
|
Others | Others |
Imiquimod Related Compound A 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67035,CAS号为 99010-24-9。 | |||
T124815 |
Barbaloin-related compound A
|
Others | Others |
Barbaloin-related compound A 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124815。 | |||
T126236 |
Clopidogrel Related Compound C
|
Others | Others |
Clopidogrel Related Compound C 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T126236,CAS号为 120202-71-3。 | |||
TP1202 |
Calcitonin Gene Related Peptide (CGRP) II, rat
CGRP II, rat |
||
Calcitonin Gene Related Peptide II is a potent, long-lasting vasodilator; activation of CGRP receptors on pancreatic β-cells increases plasma levels of pancreatic enzymes. | |||
T75736 |
Autocamtide-2-related inhibitory peptide TFA
|
||
Autocamtide-2-related inhibitory peptide (TFA) 是高度特异性的、CaMKII 的有效抑制剂,其IC50值为 40 nM。 | |||
T75737 |
Autocamtide-2-related inhibitory peptide, myristoylated TFA
|
||
Autocamtide-2-related inhibitory peptide, myristoylated TFA 是 Autocamtide-2-related inhibitory peptide 烷基化修饰后的形式。 Autocamtide-2-related inhibitory peptide 是高度特异性的、CaMKII 的有效抑制剂,其 IC50值为 40 nM。 | |||
T67456 |
Argatroban Related Compound A
|
Others | Others |
(2R,4R)-4-Methyl-1-((S)-2-(3-methylquinoline-8-sulfonamido)-5-(3-nitroguanidino)pentanoyl)piperidine-2-carboxylic acid 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T67456。 | |||
T76032 |
Calcitonin Gene Related Peptide (CGRP) II, rat TFA
|
||
CalcitoninGene Related Peptide (CGRP) II, rat TFA,为CGRP受体激活剂,具有显著且持久的血管扩张效果,适用于心血管疾病研究。 | |||
T9913 |
Ustekinumab
|
Interleukin | Immunology/Inflammation |
Ustekinumab 是一种人源化靶向抗IL-12/IL-23的单克隆 IgG1κ 抗体。 | |||
T81351 |
pTH-Related Protein (1-34) amide (human, mouse, rat)
Human PTHrP-(1-34)NH2 |
||
pTH-Related Protein (1-34) amide (human, mouse, rat) 为PTHrP的N末端片段,能够诱导高钙血症,适于研究与恶性肿瘤相关的体液性高钙血症。 | |||
T76663 |
pTH-Related Protein (1-40) (human, mouse, rat)
|
||
pTH-Related Protein (1-40) (human, mouse, rat) 促进大鼠肠细胞通过PTHR1受体和PKCα/β信号通路的钙吸收作用。该蛋白增加了甲状旁腺激素1受体(PTHR1)表达,提升了四种跨膜钙转运蛋白—TRPV6、CaBP-D9k、NCX1和PMCA1的水平。 | |||
T81350 |
pTH-Related Protein (1-37) (human, mouse, rat)
|
||
pTH-Related Protein (1-37) (human, mouse, rat) 为甲状旁腺相关蛋白 (pTHrP) 的肽段,涉及骨形成的生理调控过程。 | |||
T76301 |
Agouti-related Protein (AGRP) (83-132) Amide (human)
|
||
Agouti-related Protein (AGRP) (83-132) Amide (human),一种AGRP的片段,主要在下丘脑弓状核中表达。该化合物主要通过作为黑皮质素-4受体(MC4R)的反向激动剂来增加食物摄入。 | |||
T76636 |
(Tyr36)-pTH-Related Protein (1-36) (human, mouse, rat)
|
||
'(Tyr36)-pTH-Related Protein (1-36) (human, mouse, rat)'是用于甲状旁腺激素(PTH)受体的肽类配体。 | |||
T76363 |
[Tyr22] Calcitonin Gene Related Peptide, (22-37), rat
|
||
[Tyr22]CalcitoninGene Related Peptide, (22-37), rat 是一种大鼠降钙素基因相关肽 (CGRP) 的 22-37 片段,靶向CGRP 受体和腺苷酸环化酶。降钙素 (calcitonin) 主要由甲状腺 C 细胞产生,而 CGRP 则分泌并储存在神经系统中。 | |||
T20143 |
L-6424
L 6424,Amiodarone related compound G |
Others | Others |
L-6424 is an intermediate of Amiodarone and a non-selective ion channel blocker. It has an antiarrhythmic. | |||
T39250 |
Bevurogant
|
ROR | Metabolism |
Bevurogant 是 RORγt 受体的拮抗剂,可用于治疗慢性炎症性疾病的研究。 | |||
T81349 |
pTH-Related Protein (7-34) amide (human, mouse, rat)
|
||
pTH-Related Protein (7-34) amide (human, mouse, rat) 为一种高效的甲状旁腺激素 (PTH) 拮抗剂。 | |||
T16832 |
S18-000003
|
ROR | Metabolism |
S18-000003 是口服有活性的维甲酸相关孤儿受体 (RORγt) 选择性抑制剂,在竞争性结合试验中,对 hRORγt 的 IC50值小于 30 nM。它对 RORγt 的选择性比其他 ROR 家族成员 (IC50>10 μM)更高。它可用于银屑病的研究,胸腺畸变风险较低。 | |||
T25153 |
BIIK-0277
Levalbuterol related compound E RS,BIIK 0277 |
Others | Others |
BIIK-0277 (Levalbuterol Related Compound E) is a β2-adrenoceptor agonist, bronchodilator, and tocolytic. | |||
T83894 |
4A7C-301-Nurr1 Agonist
4A7C-301-Nuclear Receptor-Related 1 |
||
4A7C-301-Nurr1激动剂是一种核受体相关1(Nurr1)的激动剂。它通过与Nurr1配体结合域(LBD;IC50 = 48.22 nM)结合,增加了在使用SK-N-BE(2)C人神经母细胞瘤细胞进行的报告基因测定中Nurr1-LBD和全长Nurr1的转录活性(EC50s = 6.53 和 50-70 µM,分别)。每天5 mg/kg的4A7C-301-Nurr1激动剂能减少在经MPTP神经毒素或α-突触核蛋白过表达诱导的帕金森病鼠模型中纹状体和黑质compacta部分多巴胺能细胞的死亡,并减少运动和嗅觉缺陷,而不诱发类似运动障碍的行为。 | |||
T20564 |
Valsartan benzyl ester
Valsartan impurity B,Valsartan related compound C |
Others | Others |
Valsartan benzyl ester is a intermediate of Valsartan. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN4379 |
Kansuinine A
|
IL Receptor; STAT; Interleukin | Immunology/Inflammation; JAK/STAT signaling; Stem Cells |
Kansuinine A 对IL-6 诱导的 Stat3激活有作用。Kansuinine A 显示出抗病毒和抗肿瘤活性。 | |||
T2S0342 |
Armillarisin A
|
Others; Interleukin | Immunology/Inflammation; Others |
Armillarisin A 具有上调 IL-4和下调 IL-1β 的效果,对溃疡性结肠炎具有潜在的研究价值。 | |||
T40660 |
Kansuinine B
|
IL Receptor; SARS-CoV | Immunology/Inflammation; Microbiology/Virology |
Kansuinine B 抑制由 IL-6 诱导的 Stat3 活化。 Kansuinine B 具有抗病毒活性,可用于 COVID-19 研究。 | |||
T8033 |
Sodium Thiocyanate
|
Others; Reactive Oxygen Species; Interleukin | Immunology/Inflammation; Metabolism; NF-κB; Others |
Sodium thiocyanate 能够减少促炎细胞因子 IL-6水平,并增强抗炎细胞因子 IL-10水平,并显著减少 ROS 形成。 | |||
T3S1251 |
Neoruscogenin
|
ROR | Metabolism |
Neoruscogenin 是甾体 sapogenin 家族的成员,是一种可生物利用且具有高亲和力的核受体RORα (NR1F1)激动剂。 | |||
T1273 |
Diacerein
双醋瑞因,Diacerhein,Fisiodar,Diacetylrhein |
IL Receptor; Interleukin | Immunology/Inflammation |
Diacerein (Fisiodar) 是一种慢效具有白介素-1β 抑制效果的蒽醌类化合物。 | |||
T2834 |
Nobiletin
Hexamethoxyflavone,川陈皮素,川皮苷 |
Apoptosis; MMP; Reactive Oxygen Species; ROR; Autophagy | Apoptosis; Autophagy; Immunology/Inflammation; Metabolism; NF-κB; Proteases/Proteasome |
Nobiletin (Hexamethoxyflavone) 是一种来自柑橘皮的聚甲氧基黄酮,是RORs 激动剂,可改善记忆力丧失。它可降低分化的 C2C12 肌管中的ROS 水平,并具有抗炎,抗癌,抗血管生成,抗增殖,抗转移和诱导细胞凋亡作用。 | |||
T5S1252 |
Prosapogenin A
重楼皂苷E,Progenin III |
Apoptosis; Others | Apoptosis; Others |
Prosapogenin A (Progenin III) 是藜芦中的一种天然产物,通过抑制 STAT3 信号通路和糖酵解,可诱导人癌细胞凋亡,有抗癌作用。 | |||
T6S1597 |
Mulberroside A
桑皮苷 A,桑皮苷A |
TNF; Tyrosinase; Interleukin | Apoptosis; Immunology/Inflammation; Proteases/Proteasome |
Mulberroside A 是桑中的一种主要活性成分,可降低TNF-α、IL-1β和IL-6的表达,抑制 NALP3、caspase-1 和 NF-κB 的激活以及 ERK、JNK 和 p38 的磷酸化 。它抑制蘑菇酪氨酸酶,具有抗炎和抗细胞凋亡作用。 | |||
T2791 |
Pectolinarin
柳穿鱼叶苷,大蓟苷 |
Apoptosis; Others; NO Synthase; Prostaglandin Receptor; Interleukin | Apoptosis; GPCR/G Protein; Immunology/Inflammation; Others |
Pectolinarin 抑制 IL-6和 IL-8分泌以及 PGE2和 NO 产生,可通过抑制 PI3K/Akt 途径来抑制细胞增殖和炎症反应并诱导凋亡,具有抗炎活性。 | |||
TN1673 |
Garcinone C
伽升沃 C,伽升沃C |
ATM/ATR; CDK; STAT; AChR; Antifection | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; JAK/STAT signaling; Microbiology/Virology; Neuroscience; PI3K/Akt/mTOR signaling; Stem Cells |
Garcinone C 是一种从 Garcinia oblongifolia Champ 中提取的黄酮衍生物,具有抗炎、收敛和促进肉芽的活性。 Garcinone C 是一种 AChE 抑制剂,对某些癌症具有潜在的细胞毒性作用。 | |||
T3829 |
Ginsenoside F3
人参皂苷F3 |
Others; IFNAR; Interleukin | Immunology/Inflammation; Others |
Ginsenoside F3 是一种皂苷,提取自Panax ginseng 叶片。它能够调节1 型 (IL-2, IFN-γ) 及 2 型细胞因子(IL-4 and IL-10) 的产生和表达,有免疫增强的作用。 | |||
TN1189 |
13-Methylberberine chloride
13-甲基小檗碱,13-Methylberberine |
Others | Others |
13-Methylberberine chloride 是一种黄连素类似物,可增加 IL-12 的产生,并在 LPS 激活的巨噬细胞转录后抑制 iNOS 的表达,具有抗脂肪和抗肿瘤作用。 | |||
TQ0218 |
Deoxyandrographolide
去氧穿心莲内酯,14-deoxyandrographolide |
IL Receptor; TNF | Apoptosis; Immunology/Inflammation |
Deoxyandrographolide (14-deoxyandrographolide) 抑制 LPS 诱导的 iNOS mRNA 水平升高以及促炎症介质 TNF-α 和 IL-6 的产生。它增强 NGF 诱导的神经突起生长。 | |||
TN1291 |
7,3',4'-Tri-O-methylluteolin
5-Hydroxy-3',4',7-trimethoxyflavone,木犀草素-7,3',4'-三甲醚 |
TNF; COX; Interleukin | Apoptosis; Immunology/Inflammation; Neuroscience |
7,3',4'-Tri-O-methylluteolin (5-Hydroxy-3',4',7-trimethoxyflavone) 是来自草药马鞭草科的一种类黄酮,具有抗炎,解热,镇咳,抗糖尿病、抗癌和抗黑素生成特性。它以浓度依赖方式明显抑制促炎细胞因子,可显著降低在转录水平的诱导型一氧化氮合酶和环加氧酶-2 的 mRNA 表达。 | |||
T2816 |
7,8-Dihydroxyflavone
二羟基黄酮水合物,7,8-DHF |
Apoptosis; Trk receptor | Apoptosis; Tyrosine Kinase/Adaptors |
7,8-Dihydroxyflavone (7,8-DHF) 是一种选择性有效的TrkB 激动剂,其模拟脑源性神经营养因子的生理作用。它有潜力研究各种神经疾病。 | |||
T4S1521 |
1,4-Dicaffeoylquinic acid
1,4-二咖啡酰奎宁酸,洋蓟素 |
HIV Protease | Microbiology/Virology; Proteases/Proteasome |
1,4-Dicaffeoylquinic acid 是一种苯丙素类物质,从苍耳子中获得,可以减少 LPS 诱导的 TNF-α 的生成,具有抗炎活性。 | |||
T8280 |
Deacetylasperulosidic Acid
去乙酰基车叶草苷酸,去乙酰车叶草苷酸,Desacetyl asperulosidic acid |
IL Receptor; Interleukin | Immunology/Inflammation |
Deacetylasperulosidic Acid 是海巴戟果实的主要植物化学成分。它能够防止体外 4-硝基喹啉1-氧化物诱导的 DNA 损伤,抑制 IL-2的产生以及自然杀伤细胞的活化。它具有抗原活性,抑制仓鼠卵巢细胞和小鼠中染色体畸变的诱导。它可增加超氧化物歧化酶活性,从而具有抗氧化活性。 | |||
T6S2140 |
β-Anhydroicaritin
Anhydroicaritin,Beta-Anhydroicaritin,脱水淫羊藿素 |
MMP; Others; TNF; Interleukin | Apoptosis; Immunology/Inflammation; Others; Proteases/Proteasome |
β-Anhydroicaritin 是从乳香提取的一种天然产物,具有重要的生物学和药理学作用,如抗骨质疏松症,雌激素调节和抗肿瘤特性。它改善牙周组织的降解,抑制糖尿病大鼠 TNF-α 和 MMP-3 的合成和分泌。它抑制细胞内 Ca2+的升高,并显著降低 iNOS 蛋白的表达。 | |||
T1354 |
N-Acetyl-5-hydroxytryptamine
Normelatonin,N-乙酰-5-羟色胺,O-Demethylmelatonin,N-Acetylserotonin |
Trk receptor; Endogenous Metabolite | Metabolism; Tyrosine Kinase/Adaptors |
N-Acetyl-5-hydroxytryptamine (O-Demethylmelatonin) 是褪黑激素的直接前体,能够有效激活TrkB 受体。 | |||
T2720 |
Ginsenoside Rc
Panaxoside Rc,人参皂苷Rc,人参皂苷 Rc |
Others; TNF; GABA Receptor; Interleukin | Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience; Others |
Ginsenoside Rc (Panaxoside Rc) 是人参中的一种人参皂苷,可抑制 TNF-α 和 IL-1β 的表达。它增强 GABA 受体 A 介导的离子通道电流。 | |||
T2S0843 |
Negletein
黄芩素-7-甲醚,7-O-Methylbaicalein,Baicalein-7-methylether |
IL Receptor; TNF; NOS; Interleukin | Apoptosis; Immunology/Inflammation |
Negletein (7-O-Methylbaicalein) 一种神经保护剂,可增强神经生长因子的作用并诱导 PC12 细胞中的神经突生长。它通过抑制TNF-α和IL-1β表现出抗炎活性,其 IC50值分别为 16.4 和 10.8 μM。它还具有抗菌、抗缺氧和抗阿尔茨海默病活性。 | |||
T7786 |
Tryptanthrin
|
DNA gyrase | DNA Damage/DNA Repair |
Tryptanthrin 是一种口服具有活性的细胞内Leukotriene (LT) biosynthesis 抑制剂。 它能够降低大鼠胸膜炎模型中的 LTB4 水平,并抑制人全血中Leukotriene 的形成 (IC50= 10 µM)。 | |||
T2893 |
Muscone
3-Methylcyclopentadecanone,Methylexaltone,麝香酮 |
MMP; TNF; NF-κB; NOD-like Receptor (NLR); P-gp; Interleukin | Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience; NF-κB; Proteases/Proteasome |
Muscone (3-Methylcyclopentadecanone) 是中药麝香的一种主要活性单体。它抑制NF-κB 和NLRP3炎性小体的活化,显著降低炎性细胞因子水平,并最终改善心脏功能和存活率。 | |||
TN6796 |
2'-FUCOSYLLACTOSE
2'-Fucosyl-D-lactose,2'-岩藻糖基乳糖 |
Others | Others |
2'-FUCOSYLLACTOSE (2'-Fucosyl-D-lactose) 是一种含岩藻糖的寡糖。 | |||
T13502 |
3-Oxo-5β-cholanoic acid
3-氧代-5β-胆烷酸,Dehydrolithocholic acid |
ROR | Metabolism |
3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid) 是胆汁酸的一种代谢产物。3-Oxo-5β-cholanoic acid 直接与关键转录因子RORγt(Kd=1.13 μM) 结合抑制TH17细胞分化。 | |||
T2758 |
Madecassic acid
6-Deoxy-L-Galactose,羟基积雪草酸,L-Fucose,Brahmic acid,L-fucopyranose |
Others; TNF; COX; NO Synthase; Interleukin | Apoptosis; Immunology/Inflammation; Neuroscience; Others |
Madecassic acid (L-fucopyranose) 是分离自积雪草的一种天然产物,抑制iNOS、COX-2、TNF-α、IL-1beta 和IL-6,可通过在 RAW 264.7 巨噬细胞中下调NF-κB 激活而具有抗炎作用。 | |||
T6S1538 |
Neochlorogenic acid
新绿原酸,trans-5-O-Caffeoylquinic acid,Neochlorogenate,金银花,5-O-Caffeoylquinic acid |
TNF; NF-κB; COX; Antibacterial; Interleukin | Apoptosis; Immunology/Inflammation; Microbiology/Virology; Neuroscience; NF-κB |
Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) 是在干果和其他植物中发现的一种多酚类天然产物,可抑制iNOS 和COX-2蛋白表达,抑制TNF-α和IL-1β产生,还抑制磷酸化的NF-κB p65和p38 MAPK 活化。 | |||
T2932 |
Ginsenoside Rh1
Sanchinoside B2,人参皂苷 Rh1,人参皂苷Rh1,Prosapogenin A2,20(S)-Ginsenoside Rh1,Sanchinoside Rh1 |
IL Receptor; TNF; Endogenous Metabolite; PPAR; Interleukin | Apoptosis; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism |
Ginsenoside Rh1 (Sanchinoside B2) 是人参的一种主要成分,具有抗炎作用,抑制PPAR-γ,TNF-α,IL-6和IL-1β的表达。 | |||
TN1818 |
Kaempferol 3-O-β-D-glucuronide
Kaempferol-3-O-glucuronide,Kaempferol-3-beta-O-glucuronide,山奈酚葡萄糖醛酸苷,Kaempferol-3-glucuronide |
IL Receptor | Immunology/Inflammation |
Kaempferol 3-O-β-D-glucuronide (Kaempferol-3-beta-O-glucuronide) 具有抗氧化活性。 类黄酮葡糖苷酸可以被来自各种人体细胞的微粒体 α2-葡糖苷酸酶解偶联。 | |||
T4104 |
Ophiopojaponin C
麦冬皂苷C,Ophiopogonin C |
Others | Others |
Ophiopogonin C' pharmacological activities may be related to the substances in nucleus mainly. | |||
T2831 |
Glycocholic acid
Glycocholate,甘氨胆酸,cholylglycine |
Others; Endogenous Metabolite | Metabolism; Others |
Glycocholic acid (Glycocholate) 是一种胆汁酸,具有抗肿瘤活性,能够靶向作用于耐药泵和非耐药泵通路。 | |||
T3817 |
Darutigenol
|
Others | Others |
Darutigenol 是一种戊二萜,从Siegesbecikia orientalis L.中分离得到。 | |||
T3603 |
Sodium lauryl sulfoacetate
月桂醇磺基乙酸酯钠,鱼腥草,新鱼腥草素钠,Sodium houttuyfonate |
NF-κB; MAPK | MAPK; NF-κB |
Sodium lauryl sulfoacetate (Sodium houttuyfonate) 是一种植物来源的固体阴离子表面活性剂,也是一种具有抗免疫抑制作用的免疫佐剂。 | |||
T3S0687 |
Ecliptasaponin D
|
Others | Others |
Ecliptasaponin D 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 T3S0687,CAS号为 206756-04-9。 | |||
T7283 |
sodium lauroyl-α-hydroxyethyl sulfonate
鱼腥草 |
NF-κB; MAPK | MAPK; NF-κB |
sodium lauroyl-α-hydroxyethyl sulfonate 是抗假单胞菌药物,抑制假单胞菌的毒力相关运动。 | |||
T3S0631 |
Fuziline
|
Anti-infection | Microbiology/Virology |
Fuziline 是一种在附子侧根中发现的二萜生物碱。它在功能上与乌头有关。 | |||
T7671 |
Myosmine
麦司明,麦斯明 |
Others; AChR | Neuroscience; Others |
Myosmine 是存在于木贼中的一种烟草生物碱,对 a4b2 烟碱乙酰胆碱受体具有低亲和力,Ki 值为 3300 nM。 | |||
T21095 |
4-Hydroxybenzylamine
4-(Aminomethyl)phenol,4-HOBA,4-羟基苄胺 |
Endogenous Metabolite | Metabolism |
4-Hydroxybenzylamine (4-HOBA) 是内源性代谢产物的一种。 | |||
T5788 |
XYLOBIOSE
|
IL Receptor; TNF | Apoptosis; Immunology/Inflammation |
Xylobiose 是一种木糖单体的二糖,单体之间具有 β-1, 4 键。 | |||
T31467 |
Dihydrocyclosporin A
Dihydrocyclosporin-A,二氢环孢菌素A |
Others | Others |
Dihydrocyclosporin A (Dihydrocyclosporin-A) 是 cyclosporin A 的密切相关的共同代谢物。它显着抑制前鞭毛体和细胞内无鞭毛体。 | |||
T7126 |
Hydroquinine
氢化奎宁,dihydroquinine |
Others | Others |
Hydroquinine 是金鸡纳生物碱,可用于制备衍生物(如 C9 脱氢喹啉、9-乙酰氧基-10,11-二氢喹、 10,11-二氢喹单盐酸盐等)。 | |||
T1419 |
Azithromycin hydrate
CP-62993 dihydrate,阿奇霉素二水物,Azithromycin dihydrate,阿奇霉素二水合物 |
ribosome; Antibacterial; Antibiotic; Autophagy | Autophagy; Microbiology/Virology |
Azithromycin hydrate (CP-62993 dihydrate) 是一种大环内酯抗生素,可研究细菌感染。 | |||
TN6268 |
Pumiloside
(3S)-Pumiloside,短小蛇根草苷 |
||
Pumiloside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6268,CAS号为 126722-26-7。 | |||
T0592 |
D-Mannopyranose
Mannose,D-甘露糖 |
Others | Others |
D-Mannopyranose (Mannose) 是一种己糖或可发酵单糖,是甘露糖、水曲柳和相关植物的葡萄糖异构体。 | |||
T7095 |
Hexacosanoic acid
二十六酸,Cerotic acid |
Endogenous Metabolite | Metabolism |
Hexacosanoic acid 是长链脂肪酸,与多种疾病有关(如肾上腺脑白质营养不良,肾上腺髓鞘病和动脉粥样硬化)。 | |||
TMS0418 |
Dihydroergotoxine mesylate
甲磺酸二氢麦角碱,Ergoloid mesylates,甲磺酸双氢麦角毒碱 |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Dihydroergotoxine mesylate (Ergoloid mesylates) 是系列生物碱盐混合物,对GABAA 受体高结合活性。它主要用于改善与衰老相关的精神退化的症状和身体症状。 | |||
Fr16664 |
Benzothiazolone
2-Benzothiazolol |
||
Compound Fr16664 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 Fr16664,CAS号为 934-34-9。 | |||
T19538 |
(R)-(-)-1,3-Butanediol
|
Endogenous Metabolite | Metabolism |
(R)-(-)-1,3-Butanediol 是一种新型生酮酯,可在短时间内快速增加健康成人循环中 r- 和 s-ß-羟基丁酸浓度,可用于研究代谢系统相关疾病。 | |||
T2879 |
Fisetin
漆黄素,非瑟酮 |
TNF; Sirtuin; PPAR | Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism |
Fisetin 是在许多水果和蔬菜中发现的一种天然黄酮醇,有抗氧化、抗癌和神经保护作用。 | |||
------------------------ 更多 ------------------------ |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02047 |
C-Reactive Protein Protein, Rat, Recombinant (His)
C-reactive protein, pentraxin-related |
Rat | HEK293 Cells |
C-Reactive Protein Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.6 kDa and the accession number is H6X2V1. | |||
TMPY-05050 |
CEACAM5 Protein, Cynomolgus, Recombinant (His)
carcinoembryonic antigen-related cell adhesion mole... |
Cynomolgus | HEK293 Cells |
CEACAM5 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 73.5 kDa and the accession number is XP_005589491.1. | |||
TMPY-05476 |
MICA Protein, Cynomolgus, Recombinant (His)
MHC class I polypeptide-related sequence A |
Cynomolgus | HEK293 Cells |
MICA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.3 kDa and the accession number is A9UJR3. | |||
TMPY-01369 |
AGRP Protein, Human, Recombinant (His)
ASIP2,agouti related neuropeptide,AGRT,ART |
Human | HEK293 Cells |
AGRP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14 kDa and the accession number is C6SUN5. | |||
TMPY-04751 |
VRK1 Protein, Human, Recombinant
PCH1,vaccinia related kinase 1,PCH1A |
Human | Baculovirus Insect Cells |
VRK1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 45.6 kDa and the accession number is Q99986. | |||
TMPY-02258 |
Kallikrein 3/KLK3 Protein, Human, Recombinant (His)
APS,KLK2A1,PSA,kallikrein related peptidase 3,Hk3 |
Human | HEK293 Cells |
KLK3 (Kallikrein Related Peptidase 3) is a Protein Coding gene. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease that is synthesized in the epithelial cells of the prostate gland and is present in seminal plasma. KLK3, also known as Prostate Specific Antigen (PSA), kallikrein-related peptidase 3, Gamma-seminoprotein, is a secreted protein of the glandular kallikrein subfamily of serine proteases.... | |||
TMPH-00512 |
Lysenin-related protein 2 Protein, Eisenia foetida, Recombinant (His & Myc)
Hemolysin,Lysenin-related protein 2,Fetidin,Lysenin... |
Eisenia fetida | E. coli |
Pore-forming toxin that specifically binds sphingomyelin in the plasma membrane of various cells. Has hemolytic activity. It also has antibacterial activities against B.megaterium. | |||
TMPY-01066 |
MICB Protein, Human, Recombinant (His)
MHC class I polypeptide-related sequence B,PERB11.2 |
Human | HEK293 Cells |
MICB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33 kDa and the accession number is A0A7D9H7X8. | |||
TMPY-03066 |
FLT3 Ligand Protein, Mouse, Recombinant (hFc)
Ly72L,Flt3lg,fms related tyrosine kinase 3 ligand,F... |
Mouse | HEK293 Cells |
FLT3 Ligand Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.4 kDa and the accession number is P49772-1. | |||
TMPY-03215 |
FLT3 Ligand Protein, Human, Recombinant (His)
fms related tyrosine kinase 3 ligand,FLT3L,FLT3LG,F... |
Human | Baculovirus Insect Cells |
FLT3 Ligand Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 20.2 kDa and the accession number is P49771-1. | |||
TMPY-03363 |
C-Reactive Protein Protein, Human, Recombinant
C-Reactive Protein,C-reactive protein, pentraxin-related... |
Human | HEK293 Cells |
C-Reactive Protein Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 23 kDa and the accession number is P02741-1. | |||
TMPY-06873 |
FLT3 Ligand Protein, Human, Recombinant
FLT3LG,fms related tyrosine kinase 3 ligand,FLT3L,F... |
Human | E. coli |
FLT3 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.75 kDa and the accession number is P49771-1. | |||
TMPY-01647 |
CEACAM5 Protein, Human, Recombinant (His)
CD66e,CEA,carcinoembryonic antigen-related cell adh... |
Human | HEK293 Cells |
CEACAM5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 72.8 kDa and the accession number is A0A024R0K5. | |||
TMPY-00637 |
FLT1 Protein, Human, Recombinant (aa 1-328, His)
VEGFR-1,fms-related tyrosine kinase 1,VEGFR1,FLT,FL... |
Human | HEK293 Cells |
FLT1 Protein, Human, Recombinant (aa 1-328, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.6 kDa and the accession number is L7RSL3. | |||
TMPH-02646 |
Erythroferrone Protein, Mouse, Recombinant (His)
Erythroferrone,Myonectin,Erfe,Complement C1q tumor necrosis ... |
Mouse | P. pastoris (Yeast) |
Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increased iron absorption and mobilization from stores. Promotes lipid uptake into adipocytes and hepatocytes via transcriptional up-regulation of genes involved in fatty acid uptake. Erythroferrone Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted m... | |||
TMPY-01247 |
FLT3 Protein, Human, Recombinant (T227M, His)
FLK2,FLK-2,CD135,STK1,fms-related tyrosine kinase 3 |
Human | HEK293 Cells |
FLT3 Protein, Human, Recombinant (T227M, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.7 kDa and the accession number is P36888-1. | |||
TMPY-01936 |
VEGFR3/FLT4 Protein, Mouse, Recombinant (His)
Flt-4,VEGFR-3,Chy,fms related tyrosine kinase 4,VEG... |
Mouse | HEK293 Cells |
VEGFR3/FLT4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession number is P35917-1. | |||
TMPY-05850 |
CEACAM6 Protein, Cynomolgus, Recombinant (His)
carcinoembryonic antigen-related cell adhesion mole... |
Cynomolgus | HEK293 Cells |
CEACAM6 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.3 kDa and the accession number is XP_005589488.1. | |||
TMPJ-00137 |
APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)
TRDL-1,TNF- and APOL-related leukocyte expressed li... |
Human | HEK293 Cells |
APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. Secreted human APRIL, which consists almost entirely of a single TNF homology domain, shares 85% amino acid sequence identity with mouse and rat APRIL. Both APRIL and its close relative BAFF bind and signal through the TNF superfamily recept... | |||
TMPY-00747 |
Nectin-2 Protein, Human, Recombinant (His)
PVRR2,Nectin-2,poliovirus receptor-related 2 (herpe... |
Human | HEK293 Cells |
Nectin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.2 kDa and the accession number is Q92692-2. | |||
TMPY-00748 |
Nectin-2 Protein, Human, Recombinant
PRR2,Nectin-2,PVRR2,poliovirus receptor-related 2 (... |
Human | HEK293 Cells |
Nectin-2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 36.2 kDa and the accession number is Q92692-2. | |||
TMPY-00971 |
CEACAM6 Protein, Human, Recombinant (His)
NCA,CD66c,CEA,CEAL,carcinoembryonic antigen-related... |
Human | HEK293 Cells |
CEACAM6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.6 kDa and the accession number is P40199. | |||
TMPY-04123 |
CEACAM1 Protein, Human, Recombinant (His & hFc)
CEACAM‑1,carcinoembryonic antigen-related cell adhe... |
Human | HEK293 Cells |
CEACAM1 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 71.4 kDa and the accession number is P13688-8. | |||
TMPY-00949 |
VEGFR3/FLT4 Protein, Human, Recombinant (His)
VEGFR-3,PCL,FLT41,VEGF Receptor 3,VEGFR3,FLT-4,fms relat... |
Human | HEK293 Cells |
VEGFR3/FLT4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86 kDa and the accession number is P35916-1. | |||
TMPJ-00603 |
TL1A/TNFSF15 Protein, Mouse, Recombinant
TNFSF15,Tumor Necrosis Factor Ligand Superfamily Member 15,V... |
Mouse | E. coli |
Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor of endothelial cell proliferation, angiogenesis and tumor growth. TNFSF15 exerts two activities on endothelial cells: early G1 arrest of G0/G1-cells responding to growth stimuli and programmed cell death of proliferating cells. These activities are highly specific to endothelial ... | |||
TMPY-01850 |
CEACAM3 Protein, Human, Recombinant (His)
W282,W264,CEA,CD66D,CGM1,MGC119875,carcinoembryonic antigen ... |
Human | HEK293 Cells |
CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66a, CD66b, CD66c, and CD66d. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression, angiogenesis, and neutrophil activation. Abnormal overexp... | |||
TMPY-02053 |
MICA Protein, Human, Recombinant (His), MICA*018
PERB11.1,MGC21250,MIC-A,MGC111087,FLJ36918,FLJ60820,DAMA-345... |
Human | HEK293 Cells |
MICA Protein, Human, Recombinant (His), MICA*018 is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34 kDa and the accession number is AAH16929.1. | |||
TMPH-00004 |
RAC1 Protein, Human, Recombinant (His)
Ras-like protein TC25,p21-Rac1,RAC1,Cell migration-inducing ... |
Human | P. pastoris (Yeast) |
RAC1 Protein, Human, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 24.6 kDa; 30 kDa, reducing conditions and the accession number is P63000. | |||
TMPY-06608 |
Kallikrein 15/KLK15 Protein, Mouse, Recombinant (His)
kallikrein-related peptidase 15 |
Mouse | HEK293 Cells |
Kallikrein 15/KLK15 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.96 kDa and the accession number is NP_777354.1. | |||
TMPY-00630 |
AGRP Protein, Rhesus, Recombinant (mFc)
agouti related neuropeptide |
Rhesus | HEK293 Cells |
AGRP Protein, Rhesus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 32.3 kDa and the accession number is A0A8J8XRM3. | |||
TMPH-02002 |
RAB1A Protein, Human, Recombinant (GST)
RAB1A,Ras-related protein Rab-1A,YPT1-related |
Human | E. coli |
RAB1A Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 49.5 kDa and the accession number is P62820. | |||
TMPH-01911 |
NPFF Protein, Human, Recombinant (GST)
NPFF,FMRFamide-related peptides,Pro-FMRFamide-r... |
Human | E. coli |
NPFF Protein, Human, Recombinant (GST) is expressed in E. coli. | |||
TMPY-04558 |
NEK7 Protein, Human, Recombinant (His & GST)
NIMA-related kinase 7 |
Human | Baculovirus Insect Cells |
NIMA (never in mitosis gene a)-related kinase 7, NEK7 belongs to the NIMA subfamily, NEK Ser/Thr protein kinase family, protein kinase superfamily. NEKs (NIMA-related kinases) are mammalian serine/threonine (Ser/Thr) protein kinases structurally related to Aspergillus NIMA (Never in Mitosis, gene A), which plays essential roles in mitotic signaling. NEKs share an amino-terminal catalytic domain related to NIMA, an Aspergillus kinase involved in the control of several aspects of mitosis, and dive... | |||
TMPY-04443 |
NEK3 Protein, Mouse, Recombinant (His & GST)
NIMA-related kinase 3 |
Mouse | Baculovirus Insect Cells |
NEK3 (NIMA (never in mitosis gene a)-related expressed kinase 3), contains 1 protein kinase domain and is a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. Members of the NEK family of protein kinases share high amino acid homology with NIMA (never in mitosis gene a). NEK3 differs from other NimA family members in that it is not the cell cycle-regulated and is found primarily in the cytoplasm. It is activated by prolactin stimulation, leading to phosphorylatio... | |||
TMPY-00252 |
PNLIPRP1 Protein, Rat, Recombinant (His)
pancreatic lipase-related protein 1 |
Rat | HEK293 Cells |
PNLIPRP1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52 kDa and the accession number is P54316. | |||
TMPY-05579 |
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated
PRR1,ED4,PVRR,nectin-1,OFC7,SK-12,CD111,CLPED1,HVEC,poliovir... |
Human | HEK293 Cells |
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61 kDa and the accession number is Q15223-1. | |||
TMPY-02269 |
AGRP Protein, Mouse, Recombinant (His)
Art,agouti related neuropeptide,Agrt |
Mouse | HEK293 Cells |
AGRP Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.7 kDa and the accession number is P56473. | |||
TMPY-00921 |
SFRP4 Protein, Mouse, Recombinant (His)
secreted frizzled-related protein 4 |
Mouse | HEK293 Cells |
SFRP4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.4 kDa and the accession number is Q9Z1N6. | |||
TMPY-00434 |
AGRP Protein, Mouse, Recombinant (hFc)
Art,agouti related neuropeptide,Agrt |
Mouse | HEK293 Cells |
AGRP Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 34.1 kDa and the accession number is P56473. | |||
TMPH-02043 |
RHOD Protein, Human, Recombinant (His & Myc)
Rho-related GTP-binding protein RhoD,Rho-relate... |
Human | E. coli |
RHOD Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPY-00491 |
Kallikrein 15/KLK15 Protein, Human, Recombinant (hFc)
ACO,kallikrein-related peptidase 15,HSRNASPH |
Human | HEK293 Cells |
Kallikrein 15/KLK15 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.1 kDa and the accession number is Q9H2R5-1. | |||
TMPY-03017 |
Kallikrein 7/KLK7 Protein, Mouse, Recombinant (His)
Prss6,SCCE,kallikrein-related peptidase 7 |
Mouse | HEK293 Cells |
Kallikrein 7/KLK7 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.5 kDa and the accession number is Q91VE3. | |||
TMPY-03299 |
FLT1 Protein, Rat, Recombinant (His)
fms-related tyrosine kinase 1 |
Rat | HEK293 Cells |
FLT1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84 kDa and the accession number is P53767. | |||
TMPY-03963 |
CALCB Protein, Human, Recombinant (mFc)
CGRP-II,calcitonin-related polypeptide β,calcitonin... |
Human | HEK293 Cells |
CALCB, also known as CGPR and calcitonin 2, belongs to the calcitonin family. CALCB is a calcitonin (CT) peptide which may play a role in the mediation of human inflammatory diseases. It is highly expressed in the skin, blood, and cerebrospinal fluid. CGRP immunolabeling (IL) was detected in epidermal keratinocytes at levels that were especially high and widespread in the skin of humans from locations afflicted with postherpetic neuralgia (PHN) and complex region pain syndrome type 1 (CRPS), of ... | |||
TMPY-05289 |
Kallikrein 15/KLK15 Protein, Human, Recombinant (His)
ACO,HSRNASPH,kallikrein-related peptidase 15 |
Human | HEK293 Cells |
Kallikrein 15/KLK15 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.8 kDa and the accession number is Q9H2R5-1. | |||
TMPY-05332 |
FLT3 Ligand Protein, Rat, Recombinant (His)
fms related tyrosine kinase 3 ligand |
Rat | Baculovirus Insect Cells |
FLT3 Ligand Protein, Rat, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 19.7 kDa and the accession number is NP_001292868.1. | |||
TMPY-06834 |
LRP-6 Protein, Human, Recombinant (hFc)
LDL receptor related protein 6,ADCAD2 |
Human | HEK293 Cells |
LRP-6 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 95.69 kDa and the accession number is O75581. | |||
TMPY-06698 |
LRP-6 Protein, Human, Recombinant (His)
LDL receptor related protein 6,ADCAD2 |
Human | HEK293 Cells |
LRP-6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.41 kDa and the accession number is O75581-1. | |||
TMPY-00661 |
AGRP Protein, Human, Recombinant (hFc)
ART,agouti related neuropeptide,ASIP2,AGRT |
Human | HEK293 Cells |
AGRP Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39 kDa and the accession number is C6SUN5. | |||
TMPY-01783 |
SMOC1 Protein, Human, Recombinant (His)
OAS,SPARC related modular calcium binding 1 |
Human | HEK293 Cells |
SPARC-related modular calcium-binding protein 1, also known as secreted modular calcium-binding protein 1 and SMOC1, is a member of the SPARC family. SMOC1 is widely expressed in many tissues with a strongest signal in ovary. It contains two EF-hand domains, one Kazal-like domain and two thyroglobulin type-1 domains. Extracellular matrix proteins have been implicated in the regulation of osteoblast differentiation of bone marrow-derived mesenchymal stem cells (BMSCs) through paracrine or autocri... | |||
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Cat. No. | Product Name | Target | Signaling Pathways |
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TMIJ-0096 |
Buspirone EP Impurity A-d8
Buspirone USP Related Compound A-d8 |
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Buspirone EP Impurity A-d8 是 Buspirone EP Impurity A 的氘代化合物。Buspirone EP Impurity A 的 CAS 号为 20980-22-7。2-(1-Piperazinyl)pyrimidine 用作抗焦虑药。 | |||
T14687 |
Deucravacitinib
BMS-986165 |
Tyrosine Kinases; JAK; IFNAR; Interleukin | Angiogenesis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors |
Deucravacitinib (BMS-986165) 是一种高选择性、口服生物可利用的变构 TYK2 抑制剂,用于治疗自身免疫性疾病。它通过稳定调节 JH2 结构域来阻断受体介导的 Tyk2 激活,可抑制IL-12/23和 I 型IFN 途径。它选择性结合 TYK2 假激酶 (JH2) 结构域,IC50为1.0 nM。 | |||
T19261 |
D-Glucose-13C6
D-(+)-Glucose-13C6,Glucose-13C6,Dextrose-13C6 |
Endogenous Metabolite | Metabolism |
D-Glucose-13C6 (Dextrose-13C6) 是一种 D-Glucose 的同位素标记物,可作为代谢示踪剂,可用于研究机体代谢相关疾病和部分物质的代谢过程。 | |||
T10181 |
6-beta-Naloxol D5 hydrochloride
6β-Naloxol D5 hydrochloride |
Others | Others |
6-beta-Naloxol D5 hydrochloride is a deuterium-labeled opioid antagonist, closely related to naloxone, that serves as an effective compound in the field of chemical research. | |||
TMID-0058 |
Glycocholic acid-d4
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Glycocholic acid-d4 是 Glycocholic acid 的氘代化合物。Glycocholic acid 的 CAS 号为 475-31-0。Glycocholic acid 是一种胆汁酸,具有抗肿瘤活性,能够靶向作用于耐药泵和非耐药泵通路。 | |||
T11152 |
Edaravone-d5
MCI-186 D5 |
Others | Others |
Edaravone, a novel and potent free radical scavenger, effectively prevents MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator. Its deuterium-labeled variant, Edaravone D5, retains the original compound's attributes while offering isotopic labeling benefits. | |||
TNU1192 |
N1-Methyl-d3-pseudouridine
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N1-Methyl-d3-pseudouridine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 TNU1192。 | |||
T23983 |
Deutetrabenazine metabolite M4
SD-1018,Deuterated monohydroxy tetrabenazine,D6-tetrabenazine metabolite M4 |
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Deutetrabenazine metabolite M4 is believed to be related to its effect as a reversible depletion of monoamines from nerve terminals. The major circulating metabolites of Deutetrabenazine, are reversible inhibitors of VMAT2, resulting in decreased uptake | |||
T64570 |
Succinic acid-d6
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Succinic acid-d6 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64570。 | |||
T64761 |
5-(Methyl-d3)-dibenzothiophenium, 1,1,1-trifluoromethanesulfonate
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5-(Methyl-d3)-dibenzothiophenium, 1,1,1-trifluoromethanesulfonate 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64761。 | |||
T64769 |
Propan-d7-2-amine hydrochloride
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Propan-d7-2-amine hydrochloride 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64769。 | |||
T64482 |
Urea-13C
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Urea-13C 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T64482,CAS号为 58069-82-2。 | |||
T65313 |
Methy-d
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Methy-d 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65313,CAS号为 7575-93-1。 | |||
T65001 |
Benzoicacid-d5
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Benzoicacid-d5 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65001,CAS号为 1079-02-3。 | |||
T27210 |
DRX-065
DRX 065,DRX065,deuterated R-enantiomer of pioglitazone |
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DRX-065 is a stabilized and deuterated R-enantiomer of pioglitazone. DRX-065 has pharmacological properties desirable for the treatment of NASH (mitochondrial function modulation, non-steroidal anti-inflammatory effects, and glucose lowering effects) with | |||
TMID-0272 |
Cinoxacino-d8
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Cinoxacino-d8 是 Cinoxacino 的氘代化合物。Cinoxacino 的 CAS 号为 28657-80-9。Cinoxacin是一种喹诺酮类的合成抗生素, 与Oxolinic acid和 Nalidixic acid活性相似。 | |||
TMIJ-0438 |
Myosmine-2,4,5,6-d4
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Myosmine-2,4,5,6-d4 是 Myosmine 的氘代化合物。Myosmine 的 CAS 号为 532-12-7。Myosmine 是存在于木贼中的一种烟草生物碱,对 a4b2 烟碱乙酰胆碱受体具有低亲和力,Ki值为 3300 nM。 | |||
TMIJ-0229 |
Mesalamine-d3
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Mesalamine-d3 是 Mesalamine 的氘代化合物。Mesalamine 的 CAS 号为 89-57-6。5-Aminosalicylic Acid 是一种特异性的PPARγ激动剂,还抑制 p21-激活激酶1 (PAK1) 和NF-κB,具有抗炎活性。 | |||
TMID-0249 |
Terbinafine-d3 hydrochloride
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Terbinafine-d3 hydrochloride 是 Terbinafine hydrochloride 的氘代化合物。Terbinafine hydrochloride 的 CAS 号为 78628-80-5。Terbinafine hydrochloride 具有抗真菌感染活性。它是念珠菌属的角鲨烯环氧化酶的非竞争性抑制剂,Ki值为 30 nM。它还对某些革兰氏阳性和革兰氏阴性细菌具有抗菌活性。 | |||
TMIJ-0027 |
3-Methyl-2-quinoxalinecarboxylic Acid-d4
MQCA-d4 |
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3-Methyl-2-quinoxalinecarboxylic Acid-d4 是 3-Methyl-2-quinoxalinecarboxylic Acid 的氘代化合物。3-Methyl-2-quinoxalinecarboxylic Acid 的 CAS 号为 74003-63-7。3-Methyl-2-quinoxalinecarboxylic acid 在生命科学相关研究中具有广泛的应用。 | |||
TMID-0082 |
Lopinavir-d8
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Lopinavir-d8 是 Lopinavir 的氘代化合物。Lopinavir 的 CAS 号为 192725-17-0。Lopinavir 是一种选择性肽模拟 HIV-1 蛋白酶的高效抑制剂。它通过阻止 HIV-1 的成熟而起作用,从而阻断其感染性。它也是SARS-CoV 3CLpro的抑制剂。 | |||
TMIJ-0521 |
L-Lysine-4,4,5,5-d4 Hydrochloride
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L-Lysine-4,4,5,5-d4 Hydrochloride 是 L-Lysine Hydrochloride 的氘代化合物。L-Lysine Hydrochloride 的 CAS 号为 657-27-2。L-lysine hydrochloride 是一种人类必需氨基酸,能增加钙吸收,减少糖尿病相关疾病和改善肠道健康,可用于疱疹的研究。 | |||
TMIJ-0330 |
Gilteritinib-d8
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Gilteritinib-d8 是 Gilteritinib 的氘代化合物。Gilteritinib 的 CAS 号为 1254053-43-4。Gilteritinib 是一种 FLT3 抑制剂 (IC50:0.29 nM),也是一种 AXL 抑制剂 (IC50:0.73 nM),具有ATP 竞争性。 | |||
TMIJ-0112 |
Aripiprazole-d8
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Aripiprazole-d8 是 Aripiprazole 的氘代化合物。Aripiprazole 的 CAS 号为 129722-12-9。Aripiprazole 是血清素受体 5-HT1A 和多巴胺 D2 受体的部分激动剂,还用作突触后拮抗剂和血清素受体 5-HT2A 的拮抗剂。 | |||
TMID-0294 |
Taurodeoxycholic Acid-d4 Sodium Salt
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Taurodeoxycholic Acid-d4 Sodium Salt 是 Taurodeoxycholic Acid Sodium Salt 的氘代化合物。Taurodeoxycholic Acid Sodium Salt 的 CAS 号为 1180-95-6。Taurodeoxycholate sodium salt 是胆盐相关的阴离子洗涤剂,用于分离膜蛋白,包括线粒体内膜蛋白。它还可以抑制各种炎症反应。 | |||
TMIJ-0380 |
L-Lysine-13C6-15N2 Hydrochloride
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L-Lysine-13C6-15N2 Hydrochloride 是 L-Lysine Hydrochloride 的 13C 和 15 N 的标记化合物。L-Lysine Hydrochloride 的 CAS 号为 657-27-2。L-lysine hydrochloride 是一种人类必需氨基酸,能增加钙吸收,减少糖尿病相关疾病和改善肠道健康,可用于疱疹的研究。 | |||
T70990 |
ADMA-d6
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NG,NG-dimethyl-L-arginine-d6 (ADMA-d6) (hydrochloride) is intended for use as an internal standard for the quantification of NG,NG-dimethyl-L-arginine by GC- or LC-MS. ADMA is an endogenous inhibitor of nitric oxide synthase (NOS). It is formed from arginine by protein arginine methyltransferases (PRMTs) and degraded by dimethylarginine dimethylaminohydrolases (DDAHs) and alanine-glyoxylate aminotransferase 2 (AGXT2). ADMA levels are increased concomitant with an increase in blood pressure in Da... | |||
TMIJ-0044 |
Carbamazepine-d10
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Carbamazepine-d10 是 Carbamazepine 的氘代化合物。Carbamazepine 的 CAS 号为 298-46-4。Carbamazepine是与三环抗抑郁药化学相关的三环化合物,具有抗惊厥和镇痛特性。它通过减少多突触反应和阻断强直后增强发挥其抗惊厥活性。 它通常用于治疗与三叉神经痛相关的疼痛。 | |||
TMIH-0065 |
Acalabrutinib-d4
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Acalabrutinib-d4 是 Acalabrutinib 的氘代化合物。Acalabrutinib 的 CAS 号为 1420477-60-6。Acalabrutinib 是一种不可逆的、高效的、具有口服活性、选择性的第二代BTK抑制剂。它与 BTK 的 ATP 结合口袋中的 Cys481 共价结合。它在慢性淋巴细胞性白血病 (CLL) 小鼠模型中显示出强大的靶向作用和功效。 |