Hydroquinine, is an organic compound and as a cinchona alkaloid closely related to quinine.

与安慰剂相比，活性化合物治疗组在用药期间肌肉痉挛的平均次数显著下降（16.1次或58%），其差异具有高度统计学意义（Wilcoxon检验p=0.004）。每日剂量300 mg的hydroquinine hydrobromide对于预防健康女性志愿者频繁发生的普通肌肉痉挛效果显著，hydroquinine的效果持续时间超过了给药期。该化合物耐受性良好。

Twenty healthy adult volunteers experiencing at least 3 muscle cramps a week (6 men, 14 women aged 38-78 yrs) were enrolled into this study, and 19 of them completed it. Hydroquinine hydrobromide (300 mg/day) was administered to group 1 (10 women) and placebo to group 2 (4 women, 6 men). The frequency, severity, duration and location of muscle cramps as well as short-term adverse drug effects were recorded in daily diaries.