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Y-30141与广泛使用的ROCK 抑制剂Y-27632关系密切。该化合物通过竞争性结合到催化位点,抑制了ROCK-I与ROCK-II的激酶活性,其对ROCK激酶的亲和力比对其他Rho效应器激酶高出20至30倍。此外,Y-30141的抑制机制和作用谱也已进行了研究。
Y-30141与广泛使用的ROCK 抑制剂Y-27632关系密切。该化合物通过竞争性结合到催化位点,抑制了ROCK-I与ROCK-II的激酶活性,其对ROCK激酶的亲和力比对其他Rho效应器激酶高出20至30倍。此外,Y-30141的抑制机制和作用谱也已进行了研究。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 10-14周 | |
50 mg | 询价 | 10-14周 |
产品描述 | Y-30141 is closely related to the commonly used ROCK inhibitor, Y-27632. This compound inhibits the kinase activity of both ROCK-I and ROCK-II by competitively binding to the catalytic site, showing 20 to 30 times greater affinity for ROCK kinases compared to other Rho effector kinases. Furthermore, the inhibition mechanism and action profile of Y-30141 have also been investigated. |
别名 | Y30141, Y 30141 |
分子量 | 286.37 |
分子式 | C16H22N4O |
CAS No. | 199433-55-1 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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