WSF1-IN-1

Name: WSF1-IN-1
Brand: TargetMol
SKU: T39947
Rating: 4.5 (1 reviews)

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产品编号 T39947Cas号 2379577-82-7

别名 WSF1-IN-1

WSF1-IN-1 (compound 136) is an orally active inhibitor of WSF1, intended for the study of WSF1-related tumors in patients with Wolfram syndrome (WS). In HepG2 parental and HepG2 WFS1 KO cell lines, WSF1-IN-1 has demonstrated IC50 values of 0.33 μM and >27 μM, respectively.

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WSF1-IN-1

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产品编号 T39947 别名 WSF1-IN-1Cas号 2379577-82-7

规格	价格	库存
2 mg	¥ 1,630	5日内发货
5 mg	¥ 3,320	5日内发货
25 mg	¥ 13,900	6-8周
50 mg	¥ 18,300	6-8周
100 mg	¥ 28,300	6-8周
1 mL x 10 mM (in DMSO)	¥ 3,840	5日内发货

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产品描述	WSF1-IN-1 (compound 136) is an orally active inhibitor of WSF1, intended for the study of WSF1-related tumors in patients with Wolfram syndrome (WS). In HepG2 parental and HepG2 WFS1 KO cell lines, WSF1-IN-1 has demonstrated IC50 values of 0.33 μM and >27 μM, respectively.
体外活性	WSF1-IN-1 (compound 136) exhibits IC 50 values of >27 μM and 0.03 μM for Hek293 empty vector and Hek293 WFS1 over-expressor, respectively. WSF1-IN-1 (compound 136) exhibits IC 50 values of 0.05 μM (Colo-205 Control shRNA), >9 μM (Colo-205 WSF1 shRNA), 0.08 μM (DU4415 Control shRNA), 6.1 μM (DU4415 WSF1 shRNA), 0.26 μM (HepG2 Control shRNA), 2.2 μM (HepG2 WSF1 shRNA) for cell valiablity, respectively[1].
体内活性	WSF1-IN-1 (compound 136, 100 mpk qd, orally, 14 days) exhibits 106.65% tumor growth inhibition (TGI) in NSCLC patient derived xenograft OD33996 nu/nu mice[1].
别名	WSF1-IN-1