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Radicicol is an antifungal antibiotic, impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB. Radicicol is an inhibitor of Hsp90 (IC50: 1 μM). Radicicol binds to the ATPase domain of Hsp90 and prevents maturation of Hsp90 clients, leading to proteasomal degradation.
Radicicol is an antifungal antibiotic, impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB. Radicicol is an inhibitor of Hsp90 (IC50: 1 μM). Radicicol binds to the ATPase domain of Hsp90 and prevents maturation of Hsp90 clients, leading to proteasomal degradation.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
500 μg | ¥ 560 | 35日内发货 | |
1 mg | ¥ 875 | 35日内发货 | |
5 mg | ¥ 3,220 | 35日内发货 |
产品描述 | Radicicol is an antifungal antibiotic, impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB. Radicicol is an inhibitor of Hsp90 (IC50: 1 μM). Radicicol binds to the ATPase domain of Hsp90 and prevents maturation of Hsp90 clients, leading to proteasomal degradation. |
靶点活性 | HSP90:1 μM |
别名 | 根赤壳菌素, Monorden |
分子量 | 364.78 |
分子式 | C18H17ClO6 |
CAS No. | 12772-57-5 |
密度 | 1.364 g/cm3 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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