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MAO-B-IN-9是一种可穿过血脑屏障的单胺氧化酶B MAO-B 抑制剂(IC50:0.18μM),具有有效性、选择性和时间依赖性。MAO-B-IN-9具有神经保护作用,可以防止Aβ1-42诱导的神经元细胞死亡,这可能与Aβ1-42的抗聚集作用有关。
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MAO-B-IN-9是一种可穿过血脑屏障的单胺氧化酶B MAO-B 抑制剂(IC50:0.18μM),具有有效性、选择性和时间依赖性。MAO-B-IN-9具有神经保护作用,可以防止Aβ1-42诱导的神经元细胞死亡,这可能与Aβ1-42的抗聚集作用有关。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 497 | 现货 | |
5 mg | ¥ 1,230 | 现货 | |
10 mg | ¥ 1,990 | 现货 | |
25 mg | ¥ 4,130 | 现货 | |
50 mg | ¥ 5,880 | 现货 | |
100 mg | ¥ 7,950 | 现货 | |
200 mg | ¥ 10,700 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 1,370 | 现货 |
产品描述 | MAO-B-IN-9 is a monoamine oxidase B MAO-B inhibitor (IC50: 0.18 μM) that crosses the blood-brain barrier with potency, selectivity and time-dependence. MAO-B-IN-9 has neuroprotective effects against Aβ1-42-induced neuronal cell death, which may be related to the anti-aggregation effect of Aβ1-42. |
靶点活性 | MAO-B:0.178 ± 0. μM |
分子量 | 300.4 |
分子式 | C18H24N2O2 |
CAS No. | 2416910-88-6 |
存储 | Shipping with blue ice. | |||||||||||||||||||||||||
溶解度信息 | DMSO: 12 mg/mL (39.95 mM) | |||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||
DMSO
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