|
TMPH-02235
|
TMPRSS2 Protein, Human, Recombinant (Cell-Free, His)
Transmembrane protease serine 2,Serine protease 10,TMPRSS2
|
Human
|
E. coli
|
|
TMPRSS2 Protein, Human, Recombinant (Cell-Free, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 46.9 kDa and the accession number is O15393. |
|
TMPH-02536
|
BNIP3 Protein, Mouse, Recombinant (Cell-Free, His)
Bnip3,BCL2/adenovirus E1B 19 kDa protein-interacting protein...
|
Mouse
|
E. coli
|
|
Apoptosis-inducing protein that can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP... |
|
TMPH-01745
|
NOX4 Protein, Human, Recombinant (Cell-Free, His)
NOX4,Kidney oxidase-1,Renal NAD(P)H-oxidase,Kidney superoxid...
|
Human
|
E. coli
|
|
NOX4 Protein, Human, Recombinant (Cell-Free, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 69.8?kDa and the accession number is Q9NPH5. |
|
TMPH-01931
|
Cereblon/CRBN Protein, Human, Recombinant (Cell-Free, His)
CRBN,Protein cereblon
|
Human
|
E. coli
|
|
Cereblon/CRBN Protein, Human, Recombinant (Cell-Free, His) is expressed in in vitro E. coli expression system. |
|
TMPH-01101
|
Claudin-3 Protein, Human, Recombinant (Cell-Free, His)
Clostridium perfringens enterotoxin receptor 2,CPE-receptor ...
|
Human
|
E. coli
|
|
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Claudin-3 Protein, Human, Recombinant (Cell-Free, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 26.1 kDa and the accession number is O15551. |
|
TMPH-01023
|
C5AR1 Protein, Human, Recombinant (Cell-Free, His)
C5a anaphylatoxin chemotactic receptor 1,C5R1,C5a-R,C5a anap...
|
Human
|
E. coli
|
|
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. C5AR1 Protein, Human, Recombinant (Cell-Free, His) is expressed in E. coli expression syst... |
|
TMPK-00836
|
HLA-G Free Heavy Chain Protein, Human, Recombinant (His & Avi)
MHC Class I Antigen G,HLA G antigen,HLA-G,sHLA-G,HLA G,b2 mi...
|
Human
|
E. coli
|
|
HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition. |
|
TMPH-01798
|
Nucleolar transcription factor 1 Protein, Human, Recombinant (Cell-Free, His & SUMO)
Nucleolar transcription factor 1,Upstream-binding factor 1,U...
|
Human
|
E. coli
|
|
Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element. Nucleolar transcription factor 1 Protein, Human, Recombinant (Cell-Free, His & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO tag. The predicted molecular weight is 107.9 kDa and the accession number is P17480. |
|
TMPH-00596
|
Colicin-E1 Protein, E. coli, Recombinant (Cell-Free, His & Myc)
Colicin-E1,cea
|
E. coli
|
E. coli
|
|
This colicin is a channel-forming colicin. This class of transmembrane toxins depolarize the cytoplasmic membrane, leading to dissipation of cellular energy.; Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria. |
|
TMPY-03855
|
DNase I Protein, Human, Recombinant (His)
DRNI,DNL1,deoxyribonuclease I
|
Human
|
HEK293 Cells
|
|
DNase1, also known as deoxyribonuclease I and DNL1, is a member of the DNase family. DNaseI is a nuclease that cleaves DNA preferentially at phosphodiester linkages adjacent to a pyrimidine nucleotide, yielding 5'-phosphate-terminated polynucleotides with a free hydroxyl group on position 3', on average producing tetranucleotides. DNaseI binds to the cytoskeletal protein actin. It binds actin monomers with very high (sub-nanomolar) affinity and actin polymers with lower affinity. Mutations i... |
|
TMPH-01612
|
LSR Protein, Human, Recombinant (His)
Lipolysis-stimulated lipoprotein receptor,Angulin-1,LSR
|
Human
|
E. coli
|
|
Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells. |
|
TMPH-03323
|
LIPA Protein, Rat, Recombinant (His)
Lysosomal acid lipase/cholesteryl ester hydrolase,Lipa,Lipas...
|
Rat
|
E. coli
|
|
Catalyzes the deacylation of triacylglyceryl and cholesteryl ester core lipids of endocytosed low density lipoproteins to generate free fatty acids and cholesterol. LIPA Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 48.6 kDa and the accession number is Q64194. |
|
TMPH-01410
|
GPR84 Protein, Human, Recombinant (hFc)
G-protein coupled receptor 84,GPR84,Inflammation-related G-p...
|
Human
|
P. pastoris (Yeast)
|
|
Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system. GPR84 Protein, Human, Recom... |
|
TMPH-01626
|
LIPA Protein, Human, Recombinant (GST)
Lysosomal acid lipase/cholesteryl ester hydrolase,Lipase A,S...
|
Human
|
E. coli
|
|
Catalyzes the deacylation of triacylglyceryl and cholesteryl ester core lipids of endocytosed low density lipoproteins to generate free fatty acids and cholesterol. LIPA Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 70.0 kDa and the accession number is P38571. |
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TMPH-01625
|
LIPA Protein, Human, Recombinant (His)
Cholesteryl esterase,Lysosomal acid lipase/cholesteryl ester...
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Human
|
P. pastoris (Yeast)
|
|
Catalyzes the deacylation of triacylglyceryl and cholesteryl ester core lipids of endocytosed low density lipoproteins to generate free fatty acids and cholesterol. LIPA Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 45.0 kDa and the accession number is P38571. |
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TMPJ-01459
|
FGF-21 Protein, Cynomolgus, Recombinant (His)
Fibroblast Growth Factor 21,FGF-21,FGF21
|
Cynomolgus
|
HEK293 Cells
|
|
Fibroblast Growth Factor 21 (FGF21) is a growth factor that belongs to the FGF family. FGF family proteins play a central role during prenatal development and postnatal growth and regeneration of mamy tissues, by promoting cellular proliferation and differentiation. FGF21 is a potent activator of glucose uptake on adipocytes, protects animal from diet-induced obesity when overexpression in transgenic mice, and lower blood glucose and triglyceride levels when therapeutically adiministered to diab... |
|
TMPY-03222
|
PNLIP Protein, Human, Recombinant (His)
PL,pancreatic lipase,PTL,PNLIPD
|
Human
|
HEK293 Cells
|
|
PNLIP is an enzyme that belongs to the lipase family. Secreted from the pancreas, PNLIP is the primary lipase that hydrolyzes dietary fat molecules in the human digestive system, converting triglyceride substrates found in ingested oils to monoglycerides and free fatty acids. Bile salts secreted from the liver and stored in gallbladder are released into the duodenum where they coat and emulsify large fat droplets into smaller droplets, thus increasing the overall surface area of the fat, which a... |
|
TMPJ-01248
|
Cytoglobin/CYGB Protein, Human, Recombinant (His)
Stellate Cell Activation-Associated Protein,Cytoglobin,CYGB,...
|
Human
|
E. coli
|
|
Cytoglobin is a ubiquitously globin protein that belongs to the globin family. The highest expressed in heart, stomach, bladder and small intestine. CYGB acts a protector under conditions of oxidative stress. CYGB may be involved in intracellular oxygen storage or transfer, modulates oxygen and nitric oxide metabolism or scavenging free radicals within a cell. |
|
TMPH-00168
|
Levanase Protein, Bacillus subtilis, Recombinant (His)
sacC,Exo-beta-D-fructosidase,Beta-D-fructofuranosidase,Levan...
|
Bacillus subtilis
|
E. coli
|
|
Exo-fructosidase that can hydrolyze both levan and inulin, leading to the production of free fructose. Is also able to hydrolyze sucrose and to a small extent raffinose, but not melezitose, stachylose, cellobiose, maltose, and lactose. Levanase Protein, Bacillus subtilis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 77.2 kDa and the accession number is P05656. |
|
TMPH-01298
|
EPHX1 Protein, Human, Recombinant (His)
EPHX1,Microsomal epoxide hydrolase,Epoxide hydratase,Epoxide...
|
Human
|
E. coli
|
|
Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Plays a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. Metabolizes the abundant endocannabinoid 2-arachidonoylglycerol (2-AG) to free arachidonic acid (AA) and glycerol. |
|
TMPJ-01072
|
GALK2 Protein, Human, Recombinant (His)
GalNAc kinase,N-acetylgalactosamine kinase,Galactokinase 2,G...
|
Human
|
HEK293 Cells
|
|
GALK2 acts as a galactokinase when galactose is present at high concentrations. GALK2 may be involved in a salvage pathway for the reutilization of free GalNAc derived from the degradation of complex carbohydrates. GALK2 has been reported to participate in pathways , such as Amino sugar and nucleotide sugar metabolism, Galactose metabolism and Metabolic pathways. |
|
TMPH-00888
|
APEH Protein, Human, Recombinant (His)
Acylamino-acid-releasing enzyme,Acylaminoacyl-peptidase,Oxid...
|
Human
|
E. coli
|
|
This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser. APEH Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 85.2 kDa and the accession number is P13798. |
|
TMPH-00651
|
Lpp Protein, E. coli, Recombinant (His & KSI)
Major outer membrane lipoprotein Lpp,Braun lipoprotein,Murei...
|
E. coli
|
E. coli
|
|
An outer membrane lipoprotein that controls the distance between the inner and outer membranes; adding residues to Lpp increases the width of the periplasm. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to the maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane. The m... |
|
TMPH-03698
|
VSIV (strain Glasgow) Phosphoprotein Protein (His & Myc)
Phosphoprotein,P,Protein M1
|
VSIV
|
E. coli
|
|
Essential component of the RNA polymerase transcription and replication complex. Binds the viral ribonucleocapsid and positions the L polymerase on the template. May act as a chaperone for newly synthesized free N protein, so-called N(0). Plays a role in virion assembly. VSIV (strain Glasgow) Phosphoprotein Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.9 kDa and the accession number is P04879. |
|
TMPH-03337
|
MGLL Protein, Rat, Recombinant (His)
Mgll,Monoacylglycerol lipase,Monoglyceride lipase
|
Rat
|
P. pastoris (Yeast)
|
|
Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain. Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth. MGLL Protein, Rat, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 34.8 kDa and the accession nu... |
|
TMPH-02822
|
PNLIP Protein, Mouse, Recombinant (His & SUMO)
Pancreatic triacylglycerol lipase,Pnlip
|
Mouse
|
E. coli
|
|
Plays an important role in fat metabolism. It preferentially splits the esters of long-chain fatty acids at positions 1 and 3, producing mainly 2-monoacylglycerol and free fatty acids, and shows considerably higher activity against insoluble emulsified substrates than against soluble ones. PNLIP Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 65.8 kDa and the accession number is Q6P8U6. |
|
TMPH-01767
|
NPY2R Protein, Human, Recombinant (His)
Neuropeptide Y receptor type 2,NPY-Y2 receptor,NPY2R
|
Human
|
E. coli
|
|
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid. NPY2R Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 48.8 kDa and the accession number is P49146. |
|
TMPK-00258
|
Latent TGF beta 3 Protein, Human, Recombinant (His)
TGFβ3,转化生长因子,TGF-β3,TGF-beta3,TGFβ,TGF-β,ARVD,TGFB3,Latent T...
|
Human
|
HEK293 Cells
|
|
Transforming growth factor-betas (TGF-βs) are multifunctional cytokines that have been implicated in the regulation of a broad range of biological processes, including cell proliferation, cell survival, and cell differentiation. And transforming growth factor beta3 (TGFbeta3) is a key protein involved in scar-free healing observed in embryos. Latent TGF beta 3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 45.9 kDa and t... |
|
TMPH-03606
|
P3H 1 Protein, Streptomyces sp., Recombinant (His & Myc)
Proline 3-hydroxylase type I,L-proline cis-3-hydroxylase 1,P...
|
Streptomyces
|
E. coli
|
|
Dioxygenase that catalyzes the 2-oxoglutarate-dependent selective hydroxylation of free L-proline to cis-3-hydroxy-L-proline (cis-3-Hyp). D-proline, trans-4-hydroxy-L-proline, cis-4-hydroxy-L-proline, cis-4-hydroxy-D-proline, and 3,4-dehydro-DL-proline are not substrates. P3H 1 Protein, Streptomyces sp., Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 44.0 kDa and the accession number is P96010. |
|
TMPH-01432
|
HMOX1 Protein, Human, Recombinant (His)
HMOX1,Heme oxygenase 1
|
Human
|
E. coli
|
|
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis. HMOX1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHi... |
|
TMPK-01217
|
MFAP5 Protein, Mouse, Recombinant (hFc)
MP25,AAT9,MAGP2,MAGP-2,MFAP-5
|
Mouse
|
HEK293 Cells
|
|
Human basal-like breast cancer (BLBC) is an aggressive malignancy with poor prognosis. Since most current treatments are ineffective, there is an urgent need to identify therapeutic targets for BLBC. Microfibrillar-associated protein 5 (MFAP5) plays an important role in the integration of elastic microfibers and the regulation of endothelial cell behaviors.MFAP5 was significantly overexpressed in BLBC tissues and associated with poor metastasis-free survival of patients with BLBC. MFAP5 Protein,... |
|
TMPH-03696
|
VSIV (strain San Juan) Nucleoprotein/NP Protein (His & Myc)
Nucleocapsid protein,N,Nucleoprotein
|
VSIV
|
E. coli
|
|
Encapsidates the genome in a ratio of one N per nine ribonucleotides, protecting it from nucleases. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. Nucleocapsid assembly is concommitant with replication, therefore viral replication depends on the intracellular concentration of free N, termed N(0). All replicative products are resistant to nucleases. VSIV (strain San Juan) Nucleoprotein/NP Protein (His & Myc) is expressed in E. coli expressi... |
|
TMPK-00259
|
Latent TGF beta 3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
TGF-beta3,TGFβ,TGF-β,TGF-β3,TGFB3,ARVD,TGFβ3,转化生长因子,Latent T...
|
Human
|
HEK293 Cells
|
|
Transforming growth factor-betas (TGF-βs) are multifunctional cytokines that have been implicated in the regulation of a broad range of biological processes, including cell proliferation, cell survival, and cell differentiation. And transforming growth factor beta3 (TGFbeta3) is a key protein involved in scar-free healing observed in embryos. Latent TGF beta 3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with N-His tag. The predi... |
|
TMPK-00957
|
MFAP5 Protein, Human, Recombinant (hFc)
MAGP2,AAT9,MAGP-2,MP25,MFAP-5
|
Human
|
HEK293 Cells
|
|
Human basal-like breast cancer (BLBC) is an aggressive malignancy with poor prognosis. Since most current treatments are ineffective, there is an urgent need to identify therapeutic targets for BLBC. Microfibrillar-associated protein 5 (MFAP5) plays an important role in the integration of elastic microfibers and the regulation of endothelial cell behaviors.MFAP5 was significantly overexpressed in BLBC tissues and associated with poor metastasis-free survival of patients with BLBC. MFAP5 Protein,... |
|
TMPJ-00775
|
CD74 Protein, Mouse, Recombinant (mFc & His)
HLA class II histocompatibility antigen γ chain,HLA-DR antig...
|
Mouse
|
HEK293 Cells
|
|
Mouse HLA class II histocompatibility antigen gamma chain (CD74), is a single-pass type II membrane protein that in humans is encoded by the CD74 gene. It contains 1 thyroglobulin type-1 domain. CD74 Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. |
|
TMPH-02623
|
DOCK8 Protein, Mouse, Recombinant (His)
Dedicator of cytokinesis protein 8,DOCK8
|
Mouse
|
P. pastoris (Yeast)
|
|
Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP. During immune responses, required for interstitial dendritic cell (DC) migration by locally activating CDC42 at the leading edge membrane of DC. Required for CD4(+) T-cell migration in response to chemokine stimulation by promoting CDC42 activation at T cell leading edge membrane. Is involved in NK cell cytotoxicity controlling polarization of microtubule-organizing cent... |
|
TMPH-01207
|
DOCK8 Protein, Human, Recombinant (His)
DOCK8,Dedicator of cytokinesis protein 8
|
Human
|
P. pastoris (Yeast)
|
|
Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP. During immune responses, required for interstitial dendritic cell (DC) migration by locally activating CDC42 at the leading edge membrane of DC. Required for CD4(+) T-cell migration in response to chemokine stimulation by promoting CDC42 activation at T cell leading edge membrane. Is involved in NK cell cytotoxicity by controlling polarization of microtubule-organizing c... |
|
TMPH-02622
|
DOCK8 Protein, Mouse, Recombinant (E. coli, His)
DOCK8,Dedicator of cytokinesis protein 8
|
Mouse
|
E. coli
|
|
Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP. During immune responses, required for interstitial dendritic cell (DC) migration by locally activating CDC42 at the leading edge membrane of DC. Required for CD4(+) T-cell migration in response to chemokine stimulation by promoting CDC42 activation at T cell leading edge membrane. Is involved in NK cell cytotoxicity controlling polarization of microtubule-organizing cent... |
|
TMPJ-01241
|
DTD1 Protein, Human, Recombinant (His)
DUE-B,D-tyrosyl-tRNA(Tyr) deacylase 1,DNA-unwinding element-...
|
Human
|
HEK293 Cells
|
|
D-tyrosyl-tRNA(Tyr) deacylase 1(DTD1) belongs to the DTD family, and expressed in many adult and fetal tissues such as testis, ovary, spleen in adult and fetal brain. It is a nucleus and cytoplasm located protein, and is preferentially phosphorylated in cells arrested early in S phase. DTD1 is an ATPase involved in DNA replication, it may facilitate loading of CDC45 onto pre-replication complexes. The protein may hydrolyze D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr), a possible defens... |
|
TMPH-00035
|
Polyphenol oxidase 2 Protein, Agaricus bisporus, Recombinant (His)
Tyrosinase 2,Cresolase 2,PPO2,Polyphenol oxidase 2
|
Agaricus bisporus
|
Baculovirus Insect Cells
|
|
Copper-containing oxidase that catalyzes both the o-hydroxylation of monophenols and the subsequent oxidation of the resulting o-diphenols into reactive o-quinones, which evolve spontaneously to produce intermediates, which associate in dark brown pigments. Involved in the initial step of melanin synthesis. Melanins constitute a mechanism of defense and resistance to stress such as UV radiations, free radicals, gamma rays, dehydratation and extreme temperatures, and contribute to the fungal cell... |
|
TMPH-03586
|
Toxin zeta Protein, S. agalactiae, Recombinant (His)
Toxin zeta,UDP-N-acetylglucosamine kinase
|
Streptococcus agalactiae
|
P. pastoris (Yeast)
|
|
Toxic component of a type II toxin-antitoxin (TA) system. Phosphorylates UDP-N-acetyl-D-glucosamine (UNAG) on the 3'-hydroxyl group of the N-acetyl-D-glucosamine moiety, yielding UNAG-3P. UNAG-3P inhibits MurA, the first committed step in cell wall synthesis, which is then blocked. Phosphorylation is inhibited by cognate epsilon antitoxin. Part of a postsegregational killing (PSK) system involved in the killing of plasmid-free cells. The zeta toxin induces programmed cell death. Toxin zeta Prote... |
|
TMPJ-01142
|
CDO1 Protein, Human, Recombinant (His)
CDO-I,CDO,Cysteine Dioxygenase Type I,CDO1,Cysteine Dioxygen...
|
Human
|
E. coli
|
|
Cysteine Dioxygenase Type 1 (CDO1) is a mammalian non-heme iron enzyme that belongs to the cysteine dioxygenase family. CDO1 is highly expressed in the liver and placenta, and has a low expression in heart, brain and pancreas. CDO1 can also be detected in hepatoblastoma HepG2 cells. CDO1 catalyzes the conversion of L-cysteine to cysteine sulfinic acid by incorporation of dioxygen. CDO1 is a vital regulator of cellular cysteine concentrations and has an essential role in maintaining the hepatic c... |
|
TMPJ-01131
|
UBE2V2 Protein, Human, Recombinant (His)
Enterocyte Differentiation-Associated Factor 1,Vitamin D3-In...
|
Human
|
E. coli
|
|
Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2) is an enzyme that belongs to the ubiquitin-conjugating enzyme family. UBE2V2 can be detected in the placenta, colon, liver, and skin. It forms a heterodimer with UBE2N. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains and which leads to protein degradation by the proteasome. UBE2V2 mediates transcriptional activation of target genes. It plays a role in the control of progress through the cell cycle and... |
|
TMPJ-01301
|
GGACT Protein, Human, Recombinant (His)
Gamma-Glutamylaminecyclotransferase,A2LD1,AIG2-Like Domain-C...
|
Human
|
E. coli
|
|
Gamma-Glutamylaminecyclotransferase is an enzyme that converts gamma-glutamylamines to free amines and 5-oxoproline which belongs to the gamma-glutamylcyclotransferase family. It shows high activity toward gamma-glutamyl-epsilon-lysine, derived from the breakdown of fibrin and contributes to degradation of proteins cross-linked by transglutaminases. It degrades the cross-link between a lysine and a glutamic acid residue from two proteins that have been cross-linked by transglutaminases. This pro... |
|
TMPJ-00601
|
Apolipoprotein C-II/APOC2 Protein, Human, Recombinant (His)
Apolipoprotein C2,Apolipoprotein C-II,APC2 and APOC2
|
Human
|
E. coli
|
|
APOC2 activates the lipoprotein lipase in capillaries, which hydrolyzes triglycerides and thus provides free fatty acids for cells. APOC2 is component of the very low density lipoprotein (VLDL) fraction in plasma. It is also an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly. Defects in APOC2 are the cause of hyperlipoprot... |
|
TMPJ-01200
|
IMPA3 Protein, Mouse, Recombinant (His)
Inositol monophosphatase 3,Impad1
|
Mouse
|
HEK293 Cells
|
|
IMPAD1 protein (IMPA3, gPAPP or IMPase 3) belongs to the inositol monophosphatase family. It is found in Purkinje cells, brain stem, lung and chondrocytes. Mouse IMPAD1 gene encodes a type II transmembrane Golgi-embedded glycoprotein with 356 amino acid residues which generates a 306 amino acid residues mature protein after processing. It is expressed in embryo, and in theory may catalyze myo-inositol monophosphate to myo-inositol. Free myo-inositol is used to generate inositol phospholipid, an ... |
|
TMPJ-00871
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BAR Protein, S. hygroscopicus, Recombinant
bar,PPT N-acetyltransferase,Phosphinothricin-resistance prot...
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Streptomyces hygroscopicus
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E. coli
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Phosphinothricin N-acetyltransferase (PAT) is an enzyme that acetylates the free NH2 group of L-phosphinothricin (L-PPT) in the presence of acetyl-CoA as a co-substrate. It is highly specific for L-PPT and does not acetylate other L-amino acids or structurally similar molecules. L-PPT is a glutamate analog that can inhibit glutamine synthetase activity in plants, resulting in the accumulation of ammonia to toxic levels and impairment of photosynthesis. The introduction of a PAT gene into a plant... |
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TMPH-00729
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RpoH Protein, E. coli, Recombinant (His & Myc)
RNA polymerase sigma-32 factor,Heat shock regulatory protein...
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E. coli
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E. coli
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Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. Intracellular concentration of free RpoH protein increases in response to heat shock, which causes association with RNA polymerase (RNAP) and initiation of transcription of heat shock genes, including numerous global transcriptional regulators and genes involved in maintaining membrane... |
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TMPJ-00979
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GSH-S Protein, Human, Recombinant (His)
Glutathione Synthetase,GSS,GSH-S,GSH Synthetase,Glutathione ...
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Human
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E. coli
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Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine to form glutathione. Glutathione play an important role in a variety of biological functions, including detoxification of xenobiotics, protection of cells from oxidative damage by free radicals, and membrane transport. The protein functions as a homodimer to catalyze the secon... |
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TMPY-02394
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IMPA1 Protein, Human, Recombinant (His)
IMPA,inositol(myo)-1(or 4)-monophosphatase 1,IMP
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Human
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E. coli
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IMPA1 (Inositol Monophosphatase 1) is a Protein Coding gene. This gene encodes an enzyme that dephosphorylates Myo-inositol monophosphate to generate free Myo-inositol, a precursor of phosphatidylinositol, and is, therefore, an important modulator of intracellular signal transduction via the production of the second messenger's myoinositol 1,4,5-trisphosphate and diacylglycerol. Despite its many physiological functions, no clinical phenotype has been assigned to this gene dysfunction to date. Ad... |
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