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CBB1003 hydrochloride (1379573-88-2 free base)
还可以产品编号 T10698L
别名 CBB1003 hydrochloride
CBB1003 hydrochloride is a new inhibitor of histone demethylase LSD1 (IC50: 10.54 μM).
CBB1003 hydrochloride (1379573-88-2 free base)
还可以产品编号 T10698L 别名 CBB1003 hydrochloride
CBB1003 hydrochloride is a new inhibitor of histone demethylase LSD1 (IC50: 10.54 μM).
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 mg | 询价 | 期货 | |
| 500 mg | 询价 | 期货 |
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化学信息
| 产品描述 | CBB1003 hydrochloride is a new inhibitor of histone demethylase LSD1 (IC50: 10.54 μM). |
| 体外活性 | In mouse embryonic teratocarcinoma F9 cells, treatment of CBB1003 led to significant growth inhibition and the activation of CHRM4 and SCN3A expression. Treatment of mouse ES cells with CBB1003 also led to substantial inhibition of the spherical growth of ES cells [1]. CBB1003 inhibited CRC cell proliferation and colony formation. In cultured CRC cells, inhibiting LSD1 activity by CBB1003 caused a decrease in LGR5 levels while overexpression of LGR5 reduced CBB1003-induced cell death [2]. |
| 别名 | CBB1003 hydrochloride |
| 分子量 | 703.88 |
| 分子式 | C25H36Cl5N9O4 |
| 密度 | no data available |
储存&溶解度
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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