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Search Results for " drug "

Targets Recommended: Drug Metabolite Antibody-Drug Conjugates (ADCs) Drug-Linker Conjugates for ADC PKA

2316

抑制剂 & 化合物

193

天然产物

155

化合物库

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重组蛋白

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同位素标记化合物

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Cat. No.	Product Name
L8800	药物片段库		1119 compounds
	1119 种药物片段分子，是FBDD 方法新药筛选的有力工具；
L4200	FDA 上市药物库		1729 compounds
	1729 个FDA 批准药物的独特集合，可用于高通量筛选和高内涵筛选；
L2151	化疗药物库		48 compounds
	48 个肿瘤化疗药物，可以用于高通量和高内涵筛选；
L1000	上市药物库		2808 compounds
	2808 个上市药物化合物集合，可用于高通量筛选和高内涵筛选；
L9200	药物功能重定位化合物库		4630 compounds
	4630 种全球上市药物和临床药物的独特集合，可用于高通量筛选和高内涵筛选，是老药新用、新的药物靶点筛选和细胞诱导的有效工具。
L2150	抗癌药物库		3080 compounds
	3080 个具有抗癌活性小分子的独特集合，生物活性已经临床前实验证实，可用于高通量、高内涵筛选；
L4210	NMPA中国上市药物库		1270 compounds
	1270 个 NMPA 中国上市药物的独特集合，可用于高通量筛选和高内涵筛选；
L2110	抗癌上市药物库		1779 compounds
	1779 个具有抗癌活性小分子的独特集合，所有化合物都经过了严格的临床前研究和临床试验，由FDA、EMA 或NMPA 批准上市，可用于高通量、高内涵筛选。
L5800	药物代谢杂质库		197 compounds
	197 种药物异构体/代谢产物的特有集合，可用于高通量、高内涵筛选；
L2152	靶向治疗药物库		119 compounds
	119 个肿瘤靶向治疗药物，可以用于高通量和高内涵筛选；
L1010	FDA上市及药典收录分子库		3158 compounds
	3158 个上市及药典分子集合，可用于高通量筛选和高内涵筛选；
L6160	Ro5类药天然产物库		2703 compounds
	2703 种符合 RO5原则的天然产物单体集合，可以用于高通量和高内涵筛选；
L9210	儿童药物库		972 compounds
	972 种儿童药物的独特集合，可用于高通量筛选和高内涵筛选
L5510	肝脏毒性化合物库		1001 compounds
	1001 个肝脏毒性化合物的特有集合，可用于高通量、高内涵筛选，是毒理学研究的良好工具；
L1020	EMA 上市药物库		657 compounds
	657个EMA批准药物的独特集合，可用于高通量筛选和高内涵筛选
L5610	Golden骨架库		10000 compounds
	多样性好，从160万个小分子中挑选而出，10000 个化合物，5000种骨架结构；
LF9000	半胱氨酸靶向共价抑制剂库		3400 compounds
	It contains over 3,400 potential covalent modifiers.
L5600	Mini骨架库		5000 compounds
	多样性好，从一百多万个小分子中挑选而出，5000 个化合物代表5000 种骨架结构；
L9410	共价抑制剂库		1920 compounds
	1920 种小分子的独特集合，包含已发现的共价抑制剂以及包含某些共价反应基团常见弹头的分子，如氯乙酰基，2-氯丙酰基，丙烯酰基，1-丙-2-炔基，1-丁-2-炔基，酮羰基，二硫键等，可以用于共价抑制剂药物研发；
DF4000	Smart共价片段化合物库		511 compounds
	ChemDiv’s Smart Library of Covalent Fragments contains 799 compounds
LF1000	多样性核心预制库		50000 compounds
	For your convenience, there are Diversity Sets of 5,000, 10,000, 15,000, and 20,000 compounds with no structure overlap.
L6900	稀有天然产物库		693 compounds
	693 种稀有天然产物的集合，可以用于高通量和高内涵筛选；
VM1400	多样性核心库Part2		25920 compounds
	分子量<500，主要集中于250-450之间，方便后续的改造优化；
L4900	心血管毒性化合物库		131 compounds
	131 种心血管毒性化合物的独特集合，可用于毒理学研究；
DF1000	片段化合物库		11269 compounds
	ChemDiv’s Fragments Library contains 11,269 compounds.
L7820	高溶解性微型片段化合物库		1081 compounds
	高溶解性微型片段化合物库由 1081 个低分子量片段组成。
L7830	高溶解性片段药效团化合物库		985 compounds
	高溶解性片段药效团库包含985 个片段小分子。
BN1100	二代高端片段化合物库		1139 compounds
	The 2nd Generation Premium Fragment Library contains 1166 compounds.
L9230	ReFRAME 相关化合物库		3210 compounds
	3210 化合物的独特集合，可用于高通量筛选和高内涵筛选
L1500	GPCR靶点分子库		1940 compounds
	1940 种与 G 蛋白及其耦联受体相关的生物活性小分子化合物，所有小分子都具有良好的生物和药理活性，部分是 FDA 批准的上市药物；
L1580	GPCR库Plus		338 compounds
	338 种GPCR 靶向、结构新颖的化合物；
L7840	高溶解性卤化片段化合物库		796 compounds
	高溶解性卤化片段库包含796 个卤化片段化合物。
L6010	天然产物库		3840 compounds
	3840 种天然产物的独特集合，可用于高通量筛选和高内涵筛选；
L9100	磷酸酶抑制剂化合物库		79 compounds
	79 种已知活性的磷酸酶抑制剂的集合，可用于化合物筛选、化学基因组学、药理分析等方面；
L4020	NO PAINS 化合物库		9384 compounds
	TargetMol NO PAINS 化合物库包含 9384 个剔除了PAINS 的小分子活性化合物，可用于新药研发，信号通路研究，老药新用等研究。
L2570	人代谢物化合物库		4454 compounds
	4454 种人代谢物的独特集合，用于高通量、高内涵筛选；
L4150	新颖已知活性精选库		989 compounds
	989 种百里挑一的活性化合物；
L9850	口服活性化合物库		2427 compounds
	2427 种口服活性化合物独特集合，可用于高通量筛选和高内涵筛选
L1800	抗感染化合物库		2938 compounds
	2938 种具有抗感染活性的化合物的特有集合，包括抗细菌、抗真菌、抗巨细胞病毒、抗HIV、抗SARS、抗流感等活性；
L4010	已知活性化合物库		22555 compounds
	22555 个已知活性化合物的集合，可用于高通量筛选、高内涵筛选、细胞诱导和靶点确认；
L4600	植物来源化合物库		3048 compounds
	3048 个植物来源天然产物的独特集合，来自277类植物的精心之选；
L4000	经典已知活性库		14439 compounds
	14439 个已知活性化合物的集合，可用于高通量筛选、高内涵筛选、细胞诱导和靶点确认；
L3400	临床期小分子药物库		3404 compounds
	3404 个临床期化合物集合，可用于高通量筛选和高内涵筛选；
L4510	抗寄生虫库		419 compounds
	419 种具有抗寄生虫活性的小分子化合物；
L2200	酪氨酸激酶分子库		1016 compounds
	1016 种酪氨酸激酶抑制剂的独特集合，可用于高通量筛选和高内涵筛选；
L6110	生物碱类天然产物库		500 compounds
	500 种生物碱类天然产物的独特集合，可用于高通量筛选和高内涵筛选；
L1710	抗COVID-19化合物库		1133 compounds
	1133 种对SARS-CoV-2有抑制作用或潜在抑制作用的化合物集合，可用于高通量和高内涵筛选；
L2300	离子通道库		931 compounds
	931 种与离子通道相关的生物活性小分子化合物的特有集合，用于离子通道相关的疾病和药物研究，可用于高通量筛选和高内涵筛选；
L6700	抗癌天然产物库		1772 compounds
	1772 种已知活性天然产物的独特集合，是肿瘤药物开发、抗癌先导化合物筛选等领域的有力工具，可用于HTS 和HCS。
L2500	人内源代谢化合物库		499 compounds
	499 种内源性生物活性化合物的独特集合，用于高通量、高内涵筛选；
L1700	抗病毒库		1040 compounds
	1040 种具有抗病毒活性的化合物的特有集合，是筛选新型抗病毒药的有效工具；可用于高通量筛选和高内涵筛选；
L6000	高通量筛选天然产物库		4533 compounds
	4533 种天然产物的独特集合，是药物开发、药理研究、干细胞分化、指纹图谱研究、质量研究等领域的有力工具，可用于HTS 和HCS；
L9840	抗阿尔茨海默症化合物库		986 compounds
	986 种阿尔茨海默症相关的化合物集合，可用于高通量和高内涵筛选；
L4520	抗菌活性库		904 compounds
	904 种具有抗菌活性的化合物，是抗菌药物研发的有力工具；
L9900	药用辅料化合物库		182 compounds
	182 种 FDA 批准药品中的非活性成分集合
L4710	非甾体类抗炎化合物库		530 compounds
	530 种非甾体类的抗炎相关化合物，可用于高通量和高内涵筛选；
L7800	高溶解性片段库		2728 compounds
	2728 种片段分子合集，数量适中，是 FBDD 方法新药筛选的有力工具。
L6810	中药单体化合物库		2755 compounds
	2755 种中药来源的单体化合物，是药物开发、药理研究等领域的有力工具；
L5700	精选片段库		246 compounds
	246 个片段小分子的独特集合，可用于基于片段的筛选和药物发现（FBDD）；
L2190	抗肺癌化合物库		1702 compounds
	1702 种与肺癌相关的化合物，可以用于抗肺癌药物研发和药理研究；
L4400	抗生素库		692 compounds
	692 个具有抗菌活性化合物的独特集合，是医药研究的优良工具库和药物筛选的有效载体；
L5300	线粒体靶向库		812 compounds
	812 种具有潜在或确定线粒体靶向活性的化合物，以促进针对线粒体的药物研究；
L9830	抗帕金森病化合物库		857 compounds
	857 种帕金森病相关的化合物集合，可用于高通量和高内涵筛选；
L8100	细胞周期化合物库		677 compounds
	677 种细胞周期相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L6600	胃肠炎天然产物库		219 compounds
	219 种胃肠炎相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L8000	干细胞分化化合物库		1197 compounds
	1197 种干细胞分化信号通路相关的生物活性小分子化合物的特有集合，可用于高通量、高内涵筛选；
L9600	多肽分子库		791 compounds
	791 种多肽类分子，可用于多肽药物开发及信号转导通路和作用机制研究；
L5900	血脑屏障通透化合物库		509 compounds
	509 个 CNS-Penetrant 生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L7870	可溶性羧酸片段化合物库		1806 compounds
	可溶性羧酸片段库包含 1806 个化合物
L6030	天然产物衍生物虚筛化合物库		163000 compounds
	16.3万种天然产物衍生物，并且在持续增加中；
L2180	抗肿瘤库Plus		1468 compounds
	1468 种抗肿瘤相关、结构新颖的化合物；
L1400	MAPK 抑制剂库		365 compounds
	365 种与MAPK 信号通路相关的生物活性小分子化合物的特有集合，可用于高通量筛选和高内涵筛选；
L3600	细胞因子抑制剂库		604 compounds
	604 个与细胞因子紧密相关的化合物集合，是高通量、高内涵筛选的良好载体；
CB1100	EXP多样性库		50000 compounds
	For hit finding across different targets, against novel targets, or for the discovery of new chemical series against existing targets, ChemBridge offers up to 150,000 DIVERSet Library compounds in economical, pre-plated format. The DIVERSet Libraries are suitable for biochemical assays, phenotypic and other cell based assays, and assays using model organisms such as bacteria, yeast, c. elegans, zebrafish, or arabidopsis. DIVERSet Libraries have been used across many disease areas resulting in hu...
L5200	抗代谢疾病化合物库		1544 compounds
	1544 个代谢疾病相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L2193	抗肝癌化合物库		1787 compounds
	1787 种与肝癌相关的化合物，可以用于抗肝癌药物研发和药理研究；
LF9100	丝氨酸靶向共价抑制剂库		2700 compounds
	Over 2,700 small-molecule screening compounds in the library.
L1900	抗糖尿病库		683 compounds
	683 种生物活性小分子化合物；
L9300	大环化合物库		210 compounds
	210 种活性已知的大环化合物，用于高通量、高内涵筛选；
L1600	激酶抑制剂库		2720 compounds
	2720 种激酶抑制剂/调节剂的独特集合，用于特定靶向激酶，可用于高通量筛选和高内涵筛选；
L6800	中国药典收录天然产物库		2051 compounds
	2051 种中国药典收录的天然产物，是药物开发、药理研究等领域的有力工具；
L9240	农药化合物库		270 compounds
	270种农药相关化合物的独特集合，可用于高通量筛选和高内涵筛选；
DF4500	多样性核心库Part1		50000 compounds
	绝大部分分子量<500，主要集中于250-450之间，方便后续的改造优化；
L4500	抗真菌库		252 compounds
	252 个抗真菌活性化合物的独特集合，包含作用于真菌相关靶点的化合物和临床中用于真菌类疾病的药物，是相关疾病药物筛选的有效工具。
L8700	铁死亡化合物库		779 compounds
	779 种与铁死亡通路相关的化合物，可用于高通量和高内涵筛选；
L2610	神经递质受体化合物库		1513 compounds
	1513 种与神经递质受体相关的化合物，用于高通量、高内涵筛选；
DO1200	药物靶点库		53200 compounds
	数量多，含53200种小分子化合物，是高通量筛选的有力工具；
L2510	脂代谢化合物库		492 compounds
	492 个脂代谢相关的化合物集合，可用于高通量和高内涵筛选；
L6730	抗病毒中药单体化合物库		268 compounds
	268 种具有抗病毒活性的中药单体集合，是药物开发、药理研究的有效工具；
L4660	神经疾病库Plus		1246 compounds
	1246 种神经系统相关、结构新颖的化合物；
L5500	毒性化合物库		262 compounds
	262 个细胞毒性化合物的特有集合，可用于高通量、高内涵筛选。
L6710	中药抗炎分子库		1246 compounds
	1246 种具有抗炎活性或靶向炎症相关靶点的中药单体集合，是药物开发、药理研究的有效工具；
L6610	抗感染天然产物库		1060 compounds
	1060 个抗感染相关的天然产物集合，是药物开发、药理研究的有效工具；
L6100	天然多酚类化合物库		635 compounds
	635 个天然多酚化合物的独特集合，可用于高通量、高内涵筛选；
L2010	高选择性抑制剂库		575 compounds
	575种具有高选择性的抑制剂集合
L2501	人内源代谢化合物库 Plus		1283 compounds
	1283种内源性生物活性化合物的独特集合，用于高通量、高内涵筛选。
L6020	天然产物单体化合物库		16627 compounds
	16627 种精选天然产物集合，结构多样，遍布多种动植物与微生物；
L1510	核受体化合物库		531 compounds
	531 个核受体作用化合物的独特集合，可用于高通量筛选和高内涵筛选；
L1100	蛋白酶抑制剂库		343 compounds
	343 种已知的小分子蛋白酶抑制剂的特有集合，可用于高通量筛选和高内涵筛选；
L2191	抗乳腺癌化合物库		1939 compounds
	1939 种与乳腺癌相关的化合物，可以用于抗乳腺癌药物研发和药理研究；
L9610	环肽库		80 compounds
	80 种环肽分子，可用于高通量和高内涵筛选；
L7600	趋化因子抑制剂库		59 compounds
	59 种趋化因子或其受体抑制剂的独特集合，可用于高通量筛选和高内涵筛选；
L6001	Mini真菌代谢天然产物筛选库		Inquiry

L9001	食品添加剂化合物库		425 compounds
	425种食品添加剂的集合
L9810	抗纤维化化合物库		1180 compounds
	1180 种潜在的抗纤维化分子，是研究纤维化的有效工具，可以用于高通量筛选和高内涵筛选；
L3500	组蛋白修饰化合物库		469 compounds
	469 个组蛋白修饰相关的小分子化合物的特有集合，用于高通量、高内涵筛选；
L2170	肿瘤免疫治疗小分子化合物库		449 compounds
	449 种靶向肿瘤免疫治疗靶点的小分子，可用于高通量和高内涵筛选，是研究肿瘤免疫治疗的有力工具；
L6150	天然产物共价化合物库		583 compounds
	提供产品的生物学信息和药物学信息，为筛选提供理论方向和研究基础；
L2192	抗胰腺癌化合物库		2238 compounds
	2238 种与胰腺癌相关的化合物，可以用于高通量和高内涵筛选；
L2630	神经元分化化合物库		672 compounds
	672 种与神经元分化相关的化合物，可以用于神经系统疾病药物研发
L2160	抗癌活性化合物库		3188 compounds
	3188 种具有抗肿瘤活性的化合物的特有集合，用于高通量、高内涵筛选；
L2100	抗癌化合物库		7234 compounds
	7234 种肿瘤相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L6300	药食同源库		1290 compounds
	1290 个药食同源化合物的独特集合，可用于高通量筛选和高内涵筛选；
L6620	抗寄生虫天然产物库		253 compounds
	253 个抗寄生虫相关的天然产物集合，是药物开发、药理研究的有效工具；
L8200	抗衰老化合物库		3279 compounds
	3279 个抗衰老化合物的独特集合，可用于高通量筛选和高内涵筛选；
L2800	5-羟色胺分子库		268 compounds
	268 种生物活性小分子化合物，用于高通量、高内涵筛选；
L6230	苗药化合物库		534 compounds
	534种苗族特色药材的天然产物分子，可用于高通量和高内涵筛选
L3700	JAK-STAT 化合物库		252 compounds
	252 个 JAK/STAT 靶点相关的小分子化合物的独特集合，用于高通量、高内涵筛选；
L4800	血管生成库		1353 compounds
	1353 个高潜力的抑制或促进血管生成的小分子集合，可用于药物靶点开发、血管生成机理研究的高通量筛选，高内涵筛选；
L2195	抗前列腺癌化合物库		2070 compounds
	2070 种与前列腺癌相关的化合物，可以用于高通量和高内涵筛选
L4100	TGF-β/Smad靶点化合物库		184 compounds
	184 个 TGF-β/Smad 靶点相关的小分子化合物的特有集合，用于高通量、高内涵筛选；
L8110	细胞重编程化合物库		1813 compounds
	1813 种重编程信号通路相关的生物活性小分子化合物的特有集合，可用于高通量、高内涵筛选
DO2200	共价抑制剂库CD		12000 compounds
	数量多：超过12000种共价结合化合物，并且数量在持续增加；
L1720	核苷类化合物库		334 compounds
	334 种核苷类化合物，包括核苷酸、核苷酸类似物及衍生物等，适用于抗病毒、抗肿瘤、抗真菌、抗抑郁等药物的研发；
L7500	凝血与抗凝化合物库		144 compounds
	144 个化合物的独特集合，可用于高通量筛选和高内涵筛选；
L2140	癌细胞分化化合物库		406 compounds
	406 个诱导肿瘤细胞分化化合物的独特集合，可用于高通量筛选和高内涵筛选；
L1110	微管靶向化合物库		142 compounds
	142 种靶向微管的分子集合，用于高通量筛选和高内涵筛选；
L7900	成骨分子库		317 compounds
	317 种成骨相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L2130	抗癌细胞代谢库		1268 compounds
	1268 种癌细胞代谢相关的生物活性小分子化合物的特有集合，用于肿瘤相关的研究以及抗肿瘤药物的筛选，用于高通量、高内涵筛选；
L2540	肠道微生物代谢化合物库		614 compounds
	614 种肠道微生物代谢物的集合，可以用于高通量和高内涵筛选；
L1310	细胞骨架化合物库		759 compounds
	759 种细胞骨架相关的化合物，可以用于高通量和高内涵筛选；
L6400	海洋天然产物库		144 compounds
	144 种海洋来源的单体化合物，是药物开发、药理研究等领域的有力工具；
L4700	免疫/炎症分子化合物库		4720 compounds
	4720 种具有抗炎症活性的化合物的特有集合，可用于高通量筛选和高内涵筛选；
L5100	含氟化合物库		574 compounds
	574 个含氟化合物的独特集合，可用于高通量筛选和高内涵筛选；
L3100	造血毒性小分子库		101 compounds
	101 种生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L2521	糖酵解化合物库		555 compounds
	555 种糖酵解相关的活性化合物，可用于高通量和高内涵筛选
L9500	表型筛选靶点鉴定库		1796 compounds
	1796 种靶点明确的已知活性化合物，适合表型筛选；
L4300	Wnt/Hedgehog/Notch 通路化合物库		237 compounds
	237 个Wnt & Hedgehog & Notch 靶点相关的生物活性小分子化合物的特有集合，用于相关通路的研究及药物的筛选，可用于高通量、高内涵筛选。
L7110	抗高血压化合物库		678 compounds
	678 种高血压相关的小分子，用于高通量和高内涵筛选；
L7100	抗肥胖化合物库		2247 compounds
	2247 个抗肥胖化合物的独特集合，可用于高通量筛选和高内涵筛选；
L6210	藏药化合物库		747 compounds
	747 种藏药来源的天然产物分子集合，可以用于高通量和高内涵筛选；
L6220	蒙药化合物库		950 compounds
	950 种蒙药来源的天然产物分子集合，可以用于高通量和高内涵筛选；
L9400	PPI抑制剂库		485 compounds
	485 种已知活性的 PPI 相关的抑制剂，可用于高通量、高内涵筛选；
L6500	微生物天然产物库		685 compounds
	685 种微生物来源的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L2194	抗结直肠癌化合物库		1545 compounds
	1545 种与结直肠癌相关的化合物，可以用于高通量和高内涵筛选；
L1610	FDA 上市激酶抑制剂库		263 compounds
	263种靶向激酶的上市药物集合，用于特定靶向激酶，可用于高通量筛选和高内涵筛选；
L6200	瑶药化合物库		221 compounds
	221 种瑶药来源的天然产物分子集合，可以用于高通量和高内涵筛选；
L9000	细胞凋亡化合物库		1760 compounds
	1760 种与凋亡相关的生物活性小分子化合物的特有集合，多用于研究肿瘤发生发展机制和抗癌药物筛选等。可用于高通量筛选和高内涵筛选；
L1300	PI3K/Akt/mTOR 化合物库		420 compounds
	420 种与PI3K/Akt/mTOR 相关的生物活性小分子化合物的特有集合，用于PI3K/Akt/mTOR 相关研究以及高通量、高内涵筛选；
L2196	抗卵巢癌化合物库		1867 compounds
	1867 种与卵巢癌相关的化合物，可以用于抗卵巢癌药物研发和药理研究
L2550	谷氨酰胺代谢化合物库		565 compounds
	565 种谷氨酰胺代谢相关的分子，可以用于高通量和高内涵筛选；
L6820	烟草单体化合物库		747 compounds
	747种烟草单体化合物的独特集合，可用于高通量筛选和高内涵筛选
L6740	抗结直肠癌中药单体化合物库		382 compounds
	382 种抗结直肠癌相关的中药单体集合，是药物开发、药理研究的有效工具；
L6720	抗COVID-19中药单体库		1147 compounds
	根据抗新冠肺炎疫情过程中应用于临床治疗的中药方剂，收集了1147 种相关中药来源的单体化合物，可用于高通量和高内涵筛选，是抗新冠病毒药物研发的良好工具；
L8500	HIF-1化合物库		1336 compounds
	1336 个HIF-1相关小分子的独特集合，可用于缺血性疾病、癌症等相关领域的药物开发和药理研究；

化合物库

药物片段库

Cat.No: L8800

Compounds: 1119

FDA 上市药物库

Cat.No: L4200

Compounds: 1729

化疗药物库

Cat.No: L2151

Compounds: 48

上市药物库

Cat.No: L1000

Compounds: 2808

药物功能重定位化合物库

Cat.No: L9200

Compounds: 4630

抗癌药物库

Cat.No: L2150

Compounds: 3080

NMPA中国上市药物库

Cat.No: L4210

Compounds: 1270

抗癌上市药物库

Cat.No: L2110

Compounds: 1779

药物代谢杂质库

Cat.No: L5800

Compounds: 197

靶向治疗药物库

Cat.No: L2152

Compounds: 119

FDA上市及药典收录分子库

Cat.No: L1010

Compounds: 3158

Ro5类药天然产物库

Cat.No: L6160

Compounds: 2703

儿童药物库

Cat.No: L9210

Compounds: 972

肝脏毒性化合物库

Cat.No: L5510

Compounds: 1001

EMA 上市药物库

Cat.No: L1020

Compounds: 657

Golden骨架库

Cat.No: L5610

Compounds: 10000

半胱氨酸靶向共价抑制剂库

Cat.No: LF9000

Compounds: 3400

Cat.No: L5600

Compounds: 5000

共价抑制剂库

Cat.No: L9410

Compounds: 1920

Smart共价片段化合物库

Cat.No: DF4000

Compounds: 511

多样性核心预制库

Cat.No: LF1000

Compounds: 50000

稀有天然产物库

Cat.No: L6900

Compounds: 693

多样性核心库Part2

Cat.No: VM1400

Compounds: 25920

心血管毒性化合物库

Cat.No: L4900

Compounds: 131

片段化合物库

Cat.No: DF1000

Compounds: 11269

高溶解性微型片段化合物库

Cat.No: L7820

Compounds: 1081

高溶解性片段药效团化合物库

Cat.No: L7830

Compounds: 985

二代高端片段化合物库

Cat.No: BN1100

Compounds: 1139

ReFRAME 相关化合物库

Cat.No: L9230

Compounds: 3210

GPCR靶点分子库

Cat.No: L1500

Compounds: 1940

Cat.No: L1580

Compounds: 338

高溶解性卤化片段化合物库

Cat.No: L7840

Compounds: 796

天然产物库

Cat.No: L6010

Compounds: 3840

磷酸酶抑制剂化合物库

Cat.No: L9100

Compounds: 79

NO PAINS 化合物库

Cat.No: L4020

Compounds: 9384

人代谢物化合物库

Cat.No: L2570

Compounds: 4454

新颖已知活性精选库

Cat.No: L4150

Compounds: 989

口服活性化合物库

Cat.No: L9850

Compounds: 2427

抗感染化合物库

Cat.No: L1800

Compounds: 2938

已知活性化合物库

Cat.No: L4010

Compounds: 22555

植物来源化合物库

Cat.No: L4600

Compounds: 3048

经典已知活性库

Cat.No: L4000

Compounds: 14439

临床期小分子药物库

Cat.No: L3400

Compounds: 3404

抗寄生虫库

Cat.No: L4510

Compounds: 419

酪氨酸激酶分子库

Cat.No: L2200

Compounds: 1016

生物碱类天然产物库

Cat.No: L6110

Compounds: 500

抗COVID-19化合物库

Cat.No: L1710

Compounds: 1133

离子通道库

Cat.No: L2300

Compounds: 931

抗癌天然产物库

Cat.No: L6700

Compounds: 1772

人内源代谢化合物库

Cat.No: L2500

Compounds: 499

Cat.No: L1700

Compounds: 1040

高通量筛选天然产物库

Cat.No: L6000

Compounds: 4533

抗阿尔茨海默症化合物库

Cat.No: L9840

Compounds: 986

抗菌活性库

Cat.No: L4520

Compounds: 904

药用辅料化合物库

Cat.No: L9900

Compounds: 182

非甾体类抗炎化合物库

Cat.No: L4710

Compounds: 530

高溶解性片段库

Cat.No: L7800

Compounds: 2728

中药单体化合物库

Cat.No: L6810

Compounds: 2755

精选片段库

Cat.No: L5700

Compounds: 246

抗肺癌化合物库

Cat.No: L2190

Compounds: 1702

Cat.No: L4400

Compounds: 692

线粒体靶向库

Cat.No: L5300

Compounds: 812

抗帕金森病化合物库

Cat.No: L9830

Compounds: 857

细胞周期化合物库

Cat.No: L8100

Compounds: 677

胃肠炎天然产物库

Cat.No: L6600

Compounds: 219

干细胞分化化合物库

Cat.No: L8000

Compounds: 1197

多肽分子库

Cat.No: L9600

Compounds: 791

血脑屏障通透化合物库

Cat.No: L5900

Compounds: 509

可溶性羧酸片段化合物库

Cat.No: L7870

Compounds: 1806

天然产物衍生物虚筛化合物库

Cat.No: L6030

Compounds: 163000

抗肿瘤库Plus

Cat.No: L2180

Compounds: 1468

MAPK 抑制剂库

Cat.No: L1400

Compounds: 365

细胞因子抑制剂库

Cat.No: L3600

Compounds: 604

EXP多样性库

Cat.No: CB1100

Compounds: 50000

抗代谢疾病化合物库

Cat.No: L5200

Compounds: 1544

抗肝癌化合物库

Cat.No: L2193

Compounds: 1787

丝氨酸靶向共价抑制剂库

Cat.No: LF9100

Compounds: 2700

抗糖尿病库

Cat.No: L1900

Compounds: 683

大环化合物库

Cat.No: L9300

Compounds: 210

激酶抑制剂库

Cat.No: L1600

Compounds: 2720

中国药典收录天然产物库

Cat.No: L6800

Compounds: 2051

农药化合物库

Cat.No: L9240

Compounds: 270

多样性核心库Part1

Cat.No: DF4500

Compounds: 50000

Cat.No: L4500

Compounds: 252

铁死亡化合物库

Cat.No: L8700

Compounds: 779

神经递质受体化合物库

Cat.No: L2610

Compounds: 1513

药物靶点库

Cat.No: DO1200

Compounds: 53200

脂代谢化合物库

Cat.No: L2510

Compounds: 492

抗病毒中药单体化合物库

Cat.No: L6730

Compounds: 268

神经疾病库Plus

Cat.No: L4660

Compounds: 1246

毒性化合物库

Cat.No: L5500

Compounds: 262

中药抗炎分子库

Cat.No: L6710

Compounds: 1246

抗感染天然产物库

Cat.No: L6610

Compounds: 1060

天然多酚类化合物库

Cat.No: L6100

Compounds: 635

高选择性抑制剂库

Cat.No: L2010

Compounds: 575

人内源代谢化合物库 Plus

Cat.No: L2501

Compounds: 1283

天然产物单体化合物库

Cat.No: L6020

Compounds: 16627

核受体化合物库

Cat.No: L1510

Compounds: 531

蛋白酶抑制剂库

Cat.No: L1100

Compounds: 343

抗乳腺癌化合物库

Cat.No: L2191

Compounds: 1939

Cat.No: L9610

Compounds: 80

趋化因子抑制剂库

Cat.No: L7600

Compounds: 59

Mini真菌代谢天然产物筛选库

Cat.No: L6001

Compounds: Inquiry

食品添加剂化合物库

Cat.No: L9001

Compounds: 425

抗纤维化化合物库

Cat.No: L9810

Compounds: 1180

组蛋白修饰化合物库

Cat.No: L3500

Compounds: 469

肿瘤免疫治疗小分子化合物库

Cat.No: L2170

Compounds: 449

天然产物共价化合物库

Cat.No: L6150

Compounds: 583

抗胰腺癌化合物库

Cat.No: L2192

Compounds: 2238

神经元分化化合物库

Cat.No: L2630

Compounds: 672

抗癌活性化合物库

Cat.No: L2160

Compounds: 3188

抗癌化合物库

Cat.No: L2100

Compounds: 7234

药食同源库

Cat.No: L6300

Compounds: 1290

抗寄生虫天然产物库

Cat.No: L6620

Compounds: 253

抗衰老化合物库

Cat.No: L8200

Compounds: 3279

5-羟色胺分子库

Cat.No: L2800

Compounds: 268

苗药化合物库

Cat.No: L6230

Compounds: 534

JAK-STAT 化合物库

Cat.No: L3700

Compounds: 252

血管生成库

Cat.No: L4800

Compounds: 1353

抗前列腺癌化合物库

Cat.No: L2195

Compounds: 2070

TGF-β/Smad靶点化合物库

Cat.No: L4100

Compounds: 184

细胞重编程化合物库

Cat.No: L8110

Compounds: 1813

共价抑制剂库CD

Cat.No: DO2200

Compounds: 12000

核苷类化合物库

Cat.No: L1720

Compounds: 334

凝血与抗凝化合物库

Cat.No: L7500

Compounds: 144

癌细胞分化化合物库

Cat.No: L2140

Compounds: 406

微管靶向化合物库

Cat.No: L1110

Compounds: 142

成骨分子库

Cat.No: L7900

Compounds: 317

抗癌细胞代谢库

Cat.No: L2130

Compounds: 1268

肠道微生物代谢化合物库

Cat.No: L2540

Compounds: 614

细胞骨架化合物库

Cat.No: L1310

Compounds: 759

海洋天然产物库

Cat.No: L6400

Compounds: 144

免疫/炎症分子化合物库

Cat.No: L4700

Compounds: 4720

含氟化合物库

Cat.No: L5100

Compounds: 574

造血毒性小分子库

Cat.No: L3100

Compounds: 101

糖酵解化合物库

Cat.No: L2521

Compounds: 555

表型筛选靶点鉴定库

Cat.No: L9500

Compounds: 1796

Wnt/Hedgehog/Notch 通路化合物库

Cat.No: L4300

Compounds: 237

抗高血压化合物库

Cat.No: L7110

Compounds: 678

抗肥胖化合物库

Cat.No: L7100

Compounds: 2247

藏药化合物库

Cat.No: L6210

Compounds: 747

蒙药化合物库

Cat.No: L6220

Compounds: 950

PPI抑制剂库

Cat.No: L9400

Compounds: 485

微生物天然产物库

Cat.No: L6500

Compounds: 685

抗结直肠癌化合物库

Cat.No: L2194

Compounds: 1545

FDA 上市激酶抑制剂库

Cat.No: L1610

Compounds: 263

瑶药化合物库

Cat.No: L6200

Compounds: 221

细胞凋亡化合物库

Cat.No: L9000

Compounds: 1760

PI3K/Akt/mTOR 化合物库

Cat.No: L1300

Compounds: 420

抗卵巢癌化合物库

Cat.No: L2196

Compounds: 1867

谷氨酰胺代谢化合物库

Cat.No: L2550

Compounds: 565

烟草单体化合物库

Cat.No: L6820

Compounds: 747

抗结直肠癌中药单体化合物库

Cat.No: L6740

Compounds: 382

抗COVID-19中药单体库

Cat.No: L6720

Compounds: 1147

HIF-1化合物库

Cat.No: L8500

Compounds: 1336

Cat. No.	Product Name	Target	Signaling Pathways
T4661	PKG drug G1	PKA	Tyrosine Kinase/Adaptors
	PKG drug G1 靶向作用于PKG Iα。它通过 C42 PKGIα 非依赖性机制，促进血管舒张以及血压降低。
T23757	Ascorbic acid, rutoside drug combination Rutinoscorbin,Rutascorbin,Ruta C 60,Cerutin	Others	Others
	Ascorbic acid, rutoside drug combination is used for treating diabetic retinopathy.
T15058	DBCO-amine	ADC Linker	Antibody-drug Conjugate/ADC Related
	DBCO-amine 是一种可切割的 ADC 接头，用于合成抗体-药物偶联物。
T15098	Deruxtecan	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	Deruxtecan 是一种 ADC 药物-接头偶联物，由 DX-8951 (DXd) 的衍生物和马来酰亚胺-GGFG 肽接头组成，用于合成 DS-8201 和 U3-1402。
T9014	SKI-178	Apoptosis; S1P Receptor	Apoptosis; GPCR/G Protein
	SKI-178 是一种鞘氨醇激酶-1(SphK1)和 SphK2抑制剂，以 CDK1 依赖性方式诱导人急性髓性白血病细胞凋亡。
T22334	FMOC-3VVD-OH	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Fmoc-3VVD-OH 是一种可降解的 ADC 连接剂，用于合成抗体-药物偶联物。
T16218	N-Boc-PEG5-bromide	Others; PROTAC Linker; ADC Linker	Antibody-drug Conjugate/ADC Related; Others; PROTAC
	N-Boc-PEG5-bromide 是 PROTAC 的 linker，属于 PEG 类和 Alkyl/ether 类.它也是可降解的 ADC 连接桥，用于抗体药物结合物的合成。
T8547	DCBA	Drug Metabolite	Metabolism
	DCBA 是驱虫剂 N-N-diethyl-meta-toluamide (DEET) 的代谢物。尿液中 DCBA 的浓度是评估 DEET 暴露程度的指标。
T17389	AMAS	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	AMAS 是一种不可裂解的异双功能交联剂，具有 NHS 酯和马来酰亚胺基团，可实现含胺和巯基分子的共价结合。
T15179	DTSSP Crosslinker	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	DTSSP Crosslinker 是一种可降解的 ADC linker，可用于合成抗体-药物偶联物 (ADCs)。
T13621	CNDAC hydrochloride	Nucleoside Antimetabolite/Analog; Others; Drug Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others
	CNDAC hydrochloride 是一种核苷类似物，是沙帕他滨的代谢物。
T3540	IMR-1A	Gamma-secretase; Drug Metabolite	Metabolism; Neuroscience; Proteases/Proteasome; Stem Cells
	IMR-1A 是 IMR-1 的酸代谢物。IMR-1A 是 Notch 抑制剂，IC50=0.5 μM。IMR-1A 相对于 IMR-1 的效力提高了 50 倍。
T4346	SPDB	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	SPDB 是一种可降解的 ADC 连接剂，可用于合成抗体偶联药物。它是一个与 DM4 偶联物相连的小片段，利用二硫键与抗体偶联。
T15176	DSS Crosslinker	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	DSS Crosslinker 是一种不可切割的 ADC 连接剂，用于合成抗体-药物偶联物。
T18723	Succinic anhydride	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Succinic anhydride 中的环状酸酐和不可裂解的 ADC 接头。它可以与化合物 4 反应，将前药连接到靶向多肽的胺或羟基 1 基团。
T14933	Cetaben	Others	Others
	Cetaben 是不依赖 PPARα 的过氧化物酶体增殖物。它可有效降低胆固醇和甘油三酸酯的浓度，是一种非纤维化降血脂药。
T37514	Hydroxy Dimetridazole	Drug Metabolite	Metabolism
	Hydroxy Dimetridazole 是Dimetridazol 的羟基化代谢产物。Dimetridazol 是一种硝基咪唑类药物，可用于对抗原生动物感染。
T0150	Hydroxyhexamide 乙酸己脲,(±)-Hydroxyhexamid	Potassium Channel; Drug Metabolite	Membrane transporter/Ion channel; Metabolism
	Hydroxyhexamide ((±)-Hydroxyhexamid) 是Acetohexamide 的活性代谢物, 可用作降血糖药。
T12490	Pitavastatin lactone	Others; HMG-CoA Reductase	Metabolism; Others
	Pitavastatin lactone 是 Pitavastatin 在人体中的主要代谢产物。Pitavastatin 是 HMG-CoA 还原酶竞争性抑制剂。
T13131	Tert-Buthyl Pitavastatin	HMG-CoA Reductase	Metabolism
	tert-Buthyl Pitavastatin 是 Pitavastatin 的代谢产物。其中Pitavastatin 是HMG-CoA 还原酶抑制剂。
T15171	DSG Crosslinker	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	DSG Crosslinker 是用于合成抗体偶联药物的 linker，可降解。
T6741	SPDP SPDP Crosslinker	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	SPDP 是一种短链交联剂，用于通过 NHS 酯和吡啶基二硫醇反应基团与半胱氨酸巯基形成可切割（可还原）的二硫键，实现胺与巯基的共轭。它是一种可降解的 ADC 连接剂，可用于合成抗体偶联药物。
T17693	Boc-Val-Cit-PAB	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Boc-Val-Cit-PAB 是一种可切割的 ADC 接头，用于抗体-药物偶联物的合成。
T4989	Fosfomycin Tromethamine	Antibacterial; Antibiotic	Microbiology/Virology
	Fosfomycin tromethamine 是一种能透过血脑屏障的广谱抗生素，不可逆地抑制细胞壁合成的早期阶段。它对多种细菌具有杀菌活性，包括耐多药、广泛耐药和耐全药细菌。
T18479	NH-bis(C1-Boc) 亚氨基二乙酸二异丁酯	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Boc-NH-C6-Br 是一种不可切割的接头，用于抗体-药物偶联物。
T18867	Val-Cit-PAB-MMAE	Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related
	Val-Cit-PAB-MMAE 是 ADC 的药物-接头偶联物。它包含 ADC 接头（肽 Val-Cit-PAB）和有效的微管蛋白抑制剂 MMAE。
T15175	DSP Crosslinker	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	DSP Crosslinker 是一种可降解的 ADC 连接剂，用于合成可用于合成抗体偶联药物。
T8924	MFCD28987368	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	MFCD28987368 是一种可以被降解的 ADC linker，可用于抗体偶联药物 (ADC)的合成。
T10138	4-Desmethoxy Omeprazole	Drug Metabolite	Metabolism
	4-Desmethoxy Omeprazole 是 Omeprazole 的活性代谢物。Omeprazole 是质子泵抑制剂。Omeprazole 竞争性抑制 CYP2C19 活性，Ki=2 - 6 μM。Omeprazole 还抑制革兰氏阴性菌和革兰氏阳性菌生长。
T18308	MC-Gly-Gly-Phe	ADC Linker	Antibody-drug Conjugate/ADC Related
	MC-Gly-Gly-Phe 是一种用于抗体-药物偶联物的可切割接头。
T17952	Fmoc-Gly-Gly-OH	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Fmoc-Gly-Gly-OH 是一种可切割的 ADC 接头，用于合成抗体-药物偶联物。
T18728	Sulfo-SMCC sodium	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Sulfo-SMCC sodium 是一种异双功能、不可裂解的 ADC 交联剂，带有 N-羟基琥珀酰亚胺酯和马来酰亚胺基团，分别与伯胺和巯基反应。
T17983	Fmoc-Val-Cit-PAB-MMAE	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	Fmoc-Val-Cit-PAB-MMAE 由 ADC 接头 (Fmoc-Val-Cit-PAB) 和强效微管蛋白抑制剂 (MMAE) 组成。它是一种用于 ADC 的药物-接头偶联物。
T9344	3-Amino-2-oxazolidinone	Others; Endogenous Metabolite	Metabolism; Others
	3-Amino-2-oxazolidinone 是一种呋喃唑烷酮的代谢物 (metabolite)，可用作检测呋喃唑烷酮残留的一个指标。
T16045	Methotrexate metabolite DAMPA,甲喋呤杂质E	Antifolate; Drug Metabolite	Cell Cycle/Checkpoint; Metabolism
	Methotrexate metabolite (DAMPA) (DAMPA)是 Methotrexate 的活性代谢物。Methotrexate 具有拮抗叶酸 (folic acid) 的作用，被用作免疫抑制剂。
T18868	Val-Cit	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Val-Cit 是一种可切割的 ADC 接头，用于合成抗体-药物偶联物。
T22278	BOC-Dap-NE	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Boc-Dap-NE 是一种二肽，用作一种可降解的 ADC 连接剂，可用于合成抗体偶联药物。
T37600	Dasatinib N-oxide	Others; Bcr-Abl	Angiogenesis; Cytoskeletal Signaling; Others; Tyrosine Kinase/Adaptors
	Dasatinib N-oxide 是 Dasatinib 的一种次要代谢物。Dasatinib 是口服有效的Src/Bcr-Abl 抑制剂。
T17372	Ald-Ph-NHS ester	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Ald-Ph-NHS ester 是用于抗体-药物偶联的不可切割接头。
T16031	McMMAF Maleimidocaproyl monomethylauristatin F	Microtubule Associated; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Cytoskeletal Signaling
	McMMAF 是一种保护基团共轭的 MMAF。它是一种具有马来酰亚胺基己酰基接头（MC 接头）的 MMAF 衍生物， MMAF 是一种有效的微管蛋白聚合抑制剂。它可与抗体或其他蛋白质或生物聚合物结合。
T4678	Fmoc-Val-Cit-PAB	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Fmoc-Val-Cit-PAB 是一种可降解的抗体-药物偶联的连接剂。
T18540	Phe-Lys(Trt)-PAB	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Phe-Lys(Trt)-PAB 是一种组织蛋白酶可裂解的 ADC 接头，用于合成抗体-药物偶联物。
T16225	N-Hydroxysulfosuccinimide sodium	ADC Linker	Antibody-drug Conjugate/ADC Related
	N-Hydroxysulfosuccinimide sodium 是一种不可降解的 ADC 连接剂，用于合成抗体-药物偶联物。
T17691	Boc-Val-Cit-OH	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Boc-Val-Cit-OH 是一种可切割的 ADC 接头，用于合成抗体-药物偶联物。
T8722	iKIX1	Antifungal	Microbiology/Virology
	iKIX1 是一种 Pdr1 依赖性基因激活。它在体外和在播散性和泌尿道光滑念珠菌感染的动物模型中使耐药的光滑念珠菌对唑类抗真菌剂重新敏感。它可研究多药耐药性和光滑念珠菌感染。
T17213	Val-cit-PAB-OH	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Val-cit-PAB-OH 是可降解ADC 连接剂。
T38953	Azido-C6-OH	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Azido-C6-OH 是可降解的 ADC linker，可用于合成抗体偶联药物。
T3131	Fosfomycin calcium Phosphomycin calcium salt,Fosmicin,磷霉素钙	Antibacterial; Antibiotic	Microbiology/Virology
	Fosfomycin calcium (Phosphomycin calcium salt) 是一种能透过血脑屏障的广谱抗生素，不可逆地抑制细胞壁合成的早期阶段。它对多种细菌具有杀菌活性，包括耐多药、广泛耐药和耐全药细菌。
T17692	Boc-Val-Cit-PAB-PNP	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Boc-Val-Cit-PAB-PNP 是一种可切割的 ADC 接头，用于合成抗体-药物偶联物。
T18318	MC-Val-Ala-PAB-PNP	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	MC-Val-Ala-PAB-PNP 是一种用于合成抗体偶联药物的 linker，可降解。

化合物

Cat.No: T4661

Target: PKA

Ascorbic acid, rutoside drug combination

Cat.No: T23757

Synonym: Rutinoscorbin,Rutascorbin,Ruta C 60,Cerutin

Target: Others

Cat.No: T15058

Target: ADC Linker

Cat.No: T15098

Target: Others, Drug-Linker Conjugates for ADC

Cat.No: T9014

Target: Apoptosis, S1P Receptor

Cat.No: T22334

Target: Others, ADC Linker

N-Boc-PEG5-bromide

Cat.No: T16218

Target: Others, PROTAC Linker, ADC Linker

Cat.No: T8547

Target: Drug Metabolite

Cat.No: T17389

Target: Others, ADC Linker

DTSSP Crosslinker

Cat.No: T15179

Target: Others, ADC Linker

CNDAC hydrochloride

Cat.No: T13621

Target: Nucleoside Antimetabolite/Analog, Others, Drug Metabolite

Cat.No: T3540

Target: Gamma-secretase, Drug Metabolite

Cat.No: T4346

Target: Others, ADC Linker

DSS Crosslinker

Cat.No: T15176

Target: Others, ADC Linker

Succinic anhydride

Cat.No: T18723

Target: Others, ADC Linker

Cat.No: T14933

Target: Others

Hydroxy Dimetridazole

Cat.No: T37514

Target: Drug Metabolite

Hydroxyhexamide

Cat.No: T0150

Synonym: 乙酸己脲,(±)-Hydroxyhexamid

Target: Potassium Channel, Drug Metabolite

Pitavastatin lactone

Cat.No: T12490

Target: Others, HMG-CoA Reductase

Tert-Buthyl Pitavastatin

Cat.No: T13131

Target: HMG-CoA Reductase

DSG Crosslinker

Cat.No: T15171

Target: Others, ADC Linker

Cat.No: T6741

Synonym: SPDP Crosslinker

Target: Others, ADC Linker

Boc-Val-Cit-PAB

Cat.No: T17693

Target: Others, ADC Linker

Fosfomycin Tromethamine

Cat.No: T4989

Target: Antibacterial, Antibiotic

Cat.No: T18479

Synonym: 亚氨基二乙酸二异丁酯

Target: Others, ADC Linker

Val-Cit-PAB-MMAE

Cat.No: T18867

Target: Drug-Linker Conjugates for ADC

DSP Crosslinker

Cat.No: T15175

Target: Others, ADC Linker

Cat.No: T8924

Target: Others, ADC Linker

4-Desmethoxy Omeprazole

Cat.No: T10138

Target: Drug Metabolite

Cat.No: T18308

Target: ADC Linker

Fmoc-Gly-Gly-OH

Cat.No: T17952

Target: Others, ADC Linker

Sulfo-SMCC sodium

Cat.No: T18728

Target: Others, ADC Linker

Fmoc-Val-Cit-PAB-MMAE

Cat.No: T17983

Target: Others, Drug-Linker Conjugates for ADC

3-Amino-2-oxazolidinone

Cat.No: T9344

Target: Others, Endogenous Metabolite

Methotrexate metabolite

Cat.No: T16045

Synonym: DAMPA,甲喋呤杂质E

Target: Antifolate, Drug Metabolite

Cat.No: T18868

Target: Others, ADC Linker

Cat.No: T22278

Target: Others, ADC Linker

Dasatinib N-oxide

Cat.No: T37600

Target: Others, Bcr-Abl

Ald-Ph-NHS ester

Cat.No: T17372

Target: Others, ADC Linker

Cat.No: T16031

Synonym: Maleimidocaproyl monomethylauristatin F

Target: Microtubule Associated, Drug-Linker Conjugates for ADC

Fmoc-Val-Cit-PAB

Cat.No: T4678

Target: Others, ADC Linker

Phe-Lys(Trt)-PAB

Cat.No: T18540

Target: Others, ADC Linker

N-Hydroxysulfosuccinimide sodium

Cat.No: T16225

Target: ADC Linker

Cat.No: T17691

Target: Others, ADC Linker

Cat.No: T8722

Target: Antifungal

Cat.No: T17213

Target: Others, ADC Linker

Cat.No: T38953

Target: Others, ADC Linker

Fosfomycin calcium

Cat.No: T3131

Synonym: Phosphomycin calcium salt,Fosmicin,磷霉素钙

Target: Antibacterial, Antibiotic

Boc-Val-Cit-PAB-PNP

Cat.No: T17692

Target: Others, ADC Linker

MC-Val-Ala-PAB-PNP

Cat.No: T18318

Target: Others, ADC Linker

Cat. No.	Product Name	Target	Signaling Pathways
T13539	Allopurinol riboside	Others; Endogenous Metabolite; Parasite; Drug Metabolite	Metabolism; Microbiology/Virology; Others
	Allopurinol riboside 是别嘌醇的代谢产物，具有抗寄生虫作用。 Allopurinol riboside 竞争性抑制嘌呤核苷磷酸化酶对肌苷的作用，Ki 为 277 μM。
Fr13756	Isonicotinic acid	Endogenous Metabolite; Drug Metabolite	Metabolism
	Isonicotinic acid 是 Isoniazid 的代谢产物。Isoniazid 通过肼解转化为 Isonicotinic acid。 Isoniazid 向 Isonicotinic acid 的生物转化可以通过细胞色素 P450 酶催化。
T8115	Menthofuran	Others	Others
	Menthofuran 是一种天然产品。
TN4660	Niranthin	Anti-infection; HBV; PAFR; Topoisomerase	DNA Damage/DNA Repair; GPCR/G Protein; Microbiology/Virology
	Niranthin 是一种木脂素，具有广泛的药理活性。它是L. donovaniIB 拓扑异构酶的非竞争性抑制剂，可用于研究耐药利什曼病的治疗。
TN6512	Tectol	Transferase; Parasite	Metabolism; Microbiology/Virology
	Tectol 是从Lippia sidoides 中分离的，对人白血病细胞株 HL60 和 CEM 具有显著的抑制作用。它是法尼基转移酶抑制剂，在人和布氏锥虫的IC50分别为 2.09 和 1.73 μM。它具有抗疟原虫活性，是一种中等活性的生长抑制剂，IC50 为 3.44±0.20μM。
TN1740	Homoeriodictyol 高胜草酚,高圣草酚	5-HT Receptor; transporter; Sodium Channel; Drug Metabolite	GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Neuroscience
	Homoeriodictyol 是 Eriocitrin 的代谢物，属于黄酮类。Eriocitrin 是强效抗氧化剂。
T9784	Docosanedioic acid	PROTAC Linker; ADC Linker	Antibody-drug Conjugate/ADC Related; PROTAC
	Docosanedioic acid 可以作为ADC linker 或PROTAC linker，用于合成抗体偶联药物或合成 PROTAC。
T8175	DL-Laudanosine Laudanosine,DL-劳丹素	Others; Drug Metabolite	Metabolism; Others
	DL-Laudanosine (Laudanosine) 是 Atracurium 和 Cisatracurium 的代谢物，它能够透过血脑屏障，引起兴奋和癫痫。
T12095	Monomethyl fumarate	GPR; Drug Metabolite	Endocrinology/Hormones; GPCR/G Protein; Metabolism
	Monomethyl fumarate 是 Dimethyl fumarate 的活性代谢产物。Monomethyl fumarate 是一种 GPR109A 激动剂。Monomethyl fumarate 是一种 GPR109A 激动剂具有用于多种神经保护途径和其他视网膜疾病模型的潜力。
T4820	Maleimide 马来酰亚胺,2,5-Pyrroledione	Others	Others
	Maleimide (2,5-Pyrroledione) 可用于制备荧光探针，主要用于硫醇分析物的特异性检测。它也可用于制备用于癌症研究的抗体-药物偶联物 (ADC)。
T4000	(±)-Equol Equol,(±)-雌马酚,(R,S)-Equol	Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Drug Metabolite	Endocrinology/Hormones; Metabolism
	(±)-Equol ((R,S)-Equol) 是 equol 的外消旋体。它对 ERα 和 ERβ 的 EC50s of 分别为 200 和 74 nM。Equol 是大豆异黄酮黄豆苷和大豆黄素的代谢产物。
T8262	Fosfomycin sodium Fosfomycin Disodium,磷霉素钠	Antibacterial; Antibiotic	Microbiology/Virology
	Fosfomycin sodium 是一种能透过血脑屏障的广谱抗生素，不可逆地抑制细胞壁合成的早期阶段。它对多种细菌具有杀菌活性，包括耐多药、广泛耐药和耐全药的细菌。
TN1742	Homovanillyl alcohol 高香草醇,4-羟基-3-甲氧基苯乙醇	TNF; Drug Metabolite	Apoptosis; Metabolism
	Homovanillyl alcohol 是羟基酪醇的生物代谢物。Hydroxytyrosol 是存在于原始橄榄油和葡萄酒中的酚类化合物。它能够保护红细胞免受氧化损伤，并对心血管具有保护作用。
T2149	Vinburnine Eburnalritardo,L-Eburnamonine,长春布宁,Vincamone,(-)-Eburnamonine,(-)-Vincamone	Others; Drug Metabolite	Metabolism; Others
	Vinburnine (Eburnalritardo) 是一种长春花生物碱，是长春胺的代谢物和是血管扩张剂。
T8149	Dobutamine hydrochloride 盐酸多巴酚丁胺,Dobutamine (hydrochloride)	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Dobutamine hydrochloride (Dobutamine(hydrochloride)) 是一种合成的儿茶酚胺，可作用于肾上腺素能受体α1-AR、β1-AR 和β2-AR，是一种选择性的 β1-AR 受体激动剂，对 α1-AR 和 β2-AR 作用相对较弱。它能够增加心输出量，矫正低灌注。
T16338	Norgestimate metabolite Norelgestromin 17-Deacetyl norgestimate,17-Deacylnorgestimate,甲基孕酮	Drug Metabolite	Metabolism
	Norgestimate metabolite Norelgestromin (17-Deacylnorgestimate) 是norgestimate 的一种活性代谢物。它是用于避孕贴片的甾体孕激素，与雌激素乙炔雌二醇结合使用。
T7174	Urolithin A 尿石素A,3,8-二羟基-6H-二苯并[B,D]吡喃-6-酮	Apoptosis; Reactive Oxygen Species; DNA/RNA Synthesis; Endogenous Metabolite; Autophagy; Drug Metabolite	Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; NF-κB
	Urolithin A 是一种鞣花酸的肠道微生物代谢产物，可诱导自噬和凋亡，抑制细胞周期进程，抑制DNA 合成，具有抗炎、抗增殖和抗氧化的特性。
T6293	Mycophenolate Mofetil TM-MMF,吗替麦考酚酯,RS 61443	Apoptosis; Dehydrogenase; Drug Metabolite	Apoptosis; Metabolism
	Mycophenolate Mofetil (TM-MMF) 是 Mycophenolic acid 的吗啉乙酯前药。它通过抑制肌苷一磷酸脱氢酶抑制从头嘌呤合成，显示出选择性淋巴细胞抗增殖作用。
T8183	Deslanoside 洋地黄,去乙酰西地兰,Desacetyllanatoside C,Deacetyllanatoside C	ATPase; Drug Metabolite	Membrane transporter/Ion channel; Metabolism
	Deslanoside (Desacetyllanatoside C) 是一种快速作用的强心苷，可抑制Na-K-ATPase 膜泵，导致细胞内钠和钙浓度增加。它用于研究充血性心力衰竭和因折返机制引起的室上性心律失常，并在研究慢性心房颤动时控制心室率。
T0983	Penicillamine 青霉胺,d-penicillamin,Dimethyl Cysteine,D-青霉胺,Artamine,D-(-)-Penicillamine	Antibiotic	Microbiology/Virology
	Penicillamine (Artamine) 是一种 penicillin 的代谢降解产物，是一种螯合剂，可作用于威尔逊氏病。
T0617	Nicotinamide N-oxide Nicotinamide-N-oxide,Nicotinamide 1-oxide,N-氧代烟酰胺,烟酰胺-N-氧化物,1-oxynicotinamide	c-Myc; Endogenous Metabolite; CXCR; Drug Metabolite	Autophagy; Cell Cycle/Checkpoint; GPCR/G Protein; Immunology/Inflammation; Metabolism
	Nicotinamide N-oxide (Nicotinamide 1-oxide) 是生物体内烟酰胺分解代谢物，是高效选择性CXCR2受体拮抗剂。
T4710	3-Methoxytyramine hydrochloride 3-O-methyl Dopamine hydrochloride,3-O-methyl Dopamine hydrochloride),3-O-甲基多巴胺盐酸盐	Others; Endogenous Metabolite; Drug Metabolite	Metabolism; Others
	3-Methoxytyramine hydrochloride (3-O-methyl Dopamine hydrochloride) 是多巴胺的无活性代谢物，能够活化痕量胺相关受体1 。
T5320	Tulipalin A α-methylene-γ-butyrolactone,2-Methylenebutyrolactone,2-甲烯基丁内酯	Others; Drug Metabolite	Metabolism; Others
	Tulipalin A (α-methylene-γ-butyrolactone) 是来源于郁金香鳞茎的有毒糖苷。Tulipalin A 是引起过敏性接触皮炎的致敏性致敏物 (causative allergen)，在低剂量影响免疫细胞的功能，例如 Jurkat T 细胞。
T17143	Toyocamycin 丰加霉素,Vengicide	Apoptosis; Others; IRE1; Antibiotic; Antifungal	Apoptosis; Cell Cycle/Checkpoint; Microbiology/Virology; Others
	Toyocamycin (Vengicide) 是放线菌类产生的腺苷类似物，为 X 盒结合蛋白 1 (XBP1) 抑制剂，抑制 IRE1α 诱导的 ATP 依赖性 XBP1 mRNA 的断裂，IC50值为 80 nM。它还诱导凋亡。
T13808	p-Coumaric Acid Ethyl Ester 对香豆酸乙酯,Ethyl (E)-p-hydroxycinnamate,Ethyl trans-4-hydroxycinnamate	Others; Drug Metabolite	Metabolism; Others
	p-Coumaric Acid Ethyl Ester (Ethyl (E)-p-hydroxycinnamate) 是 p-Coumaric acid 的乙酯形式。p-Coumaric Acid 是一种免疫抑制剂，能够用于自身免疫性炎性疾病 (如类风湿关节炎) 的研究。
T3797	Isosilybin Isosilybinin,Isosilibinin,异水飞蓟宾,Silymarin,Silybin B,Q-100795	P450	Metabolism
	Isosilybin (Isosilibinin) 是一种类黄酮，来源于乳蓟；能够抑制CYP3A4诱导(IC50:74 μM)。
T3212	Digoxigenin 地谷新配基,异羟基洋地黄毒苷元	Others	Others
	Digoxigenin, a therapeutic drug belonging to the group of cardiac glycosides, is widely used in the management of congestive heart failure and other cardiac diseases
T3669	Curcumenol (+)-Curcumenol,莪术醇	P450	Metabolism
	Curcumenol ((+)-Curcumenol) 提取具有药用价值的 Curcuma zedoaria，是高效的 CYP3A4抑制剂(IC50=12.6 μM)，具有神经抗肿瘤、保护、抗炎、和保肝的作用。它在 LPS 刺激的 BV-2 小胶质细胞中，抑制 Akt 介导的 NF-κB 活化及 p38 MAPK 信号通路。
TWO2771	2-Adamantanol 2-金刚烷醇,Adamantan-2-Ol,2-Hydroxyadamantane	Others	Others
	2-Adamantanol (2-Hydroxyadamantane) 用于合成抗过敏药物Mizolastine。
T1468	Lornoxicam Ro 13-9297,Chlortenoxicam,TS110,氯诺昔康	COX; Endogenous Metabolite	Immunology/Inflammation; Metabolism; Neuroscience
	Lornoxicam (Chlortenoxicam) 是一种新型非甾体抗炎药，是高活性 COX-1 和 COX-2 抑制剂，IC50 分别为 5 和 8 nM。
T3327	Artemotil SM-227,β-Arteether,Beta-Arteether,蒿乙醚,Arteether,(+)-Arteether	CXCR; CCR; Parasite	Autophagy; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology
	Artemotil (SM-227) 是一种新型的速效抗疟药，可研究耐Plasmodium falciparum 的恶性疟原虫疟疾，IC50值为 1.61 nM。
T6S2243	Alisol A 24-acetate Alisol A 24-monoacetate,Alisol A monoacetate,泽泻醇A24-醋酸酯	Others	Others
	Alisol A 24-acetate (Alisol A monoacetate) 是一种天然产物。
T5567	Tetradecanedioic acid 十四烷二酸,Tetradecanedicarboxylate	Others; Endogenous Metabolite	Metabolism; Others
	Tetradecanedioic acid (Tetradecanedicarboxylate) 是一种长链脂肪酸，属于内源性代谢物的一种。它能够作为有机阴离子转运多肽介导的药物-药物相互作用的候选生物标志物。
T3820	Iridin 野鸢尾苷,Lridin	Others	Others
	Iridin (Lridin) 是抑制异黄酮化合物，从Iris milesii 中提取得到。
T10147	4-Hydroxymephenytoin (+/-)-4'-Hydroxymephenytoin	Others; Drug Metabolite	Metabolism; Others
	4-Hydroxymephenytoin ((+/-)-4'-Hydroxymephenytoin) 是抗癫痫药 mephenytoin 的代谢产物。Mephenytoin 是 CYP2C19的配体。
T7936	Benzopinacole	Others	Others
	Benzopinacole 是一种抗阿米巴药物，可作为中间体合成多种化合物。
T0681	Rifampicin Rifamycin AMP,利福平,Rimactane,Rifampin	Influenza Virus; DNA/RNA Synthesis; Antibacterial; Antibiotic; Antifection	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Rifampicin (Rifamycin AMP) 是广谱抗生素，可抵抗细菌病原体以及具有抗流感病毒活性。
T4S0647	Butylphthalide 丁基苯酞,3-Butylphthalide,3-n-Butylphathlide,3-n-Butylphthalide	Others	Others
	Butylphthalide (3-Butylphthalide) 是一种抗脑缺血药物，最初分离自芹菜种中，对中风动物模型有效。
T2959	Ginsenoside Rh2 20(S)-Rh2,20S-Ginsenoside Rh2,人参皂苷Rh2,20(S)-Ginsenoside Rh2,人参皂苷 Rh2	Apoptosis; EGFR; Caspase; Endogenous Metabolite	Angiogenesis; Apoptosis; JAK/STAT signaling; Metabolism; Proteases/Proteasome; Tyrosine Kinase/Adaptors
	Ginsenoside Rh2 (20(S)-Ginsenoside Rh2) 诱导caspase-8和caspase-9活化。它以多途径方式诱导癌细胞凋亡。
T1381	Milbemycin oxime	Others; Antibiotic; Parasite	Microbiology/Virology; Others
	Milbemycin oxime 是一种大环内酯，具有广谱抗寄生虫活性。它由 Milbemycin A4 和 A3 组成。它可结合谷氨酸门控的氯离子通道，可作用于肠道线虫，肺和心脏蠕虫。
T22286	Cyanosafracin B Cyanoquinonamine,氰基番红菌素 B,CBR28-1	Others	Others
	Cyanosafracin B (Cyanoquinonamine) 是一种合成 Phthalascidin Pt-650 及 Ecteinascidin ET-743 的起始原料。
T0254	Probucol DH-581,普罗布考	Virus Protease; ABC; Lipid	Membrane transporter/Ion channel; Metabolism; Microbiology/Virology
	Probucol (DH-581) 是一种抗高脂血症药物，可通过增加 LDL 分解代谢率来降低血液中的胆固醇水平。
T4S0051	Coptisine sulfate	Indoleamine 2,3-Dioxygenase (IDO)	Metabolism
	Coptisine Sulfate 是一种从黄连中分离到的生物碱，是非竞争性的IDO 抑制剂，Ki=为 5.8 μM，IC50=6.3 μM。
T3S2381	Perillene 3-Isohexenylfuran,紫苏烯,Perillen	Others; Antibacterial	Microbiology/Virology; Others
	Perillene (3-Isohexenylfuran) 是促进肠蠕动的药物中的活性成分，它对金黄色葡萄球菌和大肠杆菌具有很强的抗药性。
T1285	Anethole trithione 茴三硫,Anetholtrithion	Others; AChR	Neuroscience; Others
	Anethole trithione (Anetholtrithion) 是硫杂环胆碱，是一种胆汁分泌刺激剂，可增强唾液分泌并增加 mAChR 受体，用于口干症的研究。
TN3967	Epieriocalyxin A	ERK; BCL; ROS; Caspase; DNA/RNA Synthesis; JNK	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; MAPK; Proteases/Proteasome
	Epieriocalyxin A 可以抑制 Caco-2 结肠癌细胞的生长。它可能是未来结肠癌治疗的潜在药物。
TQ0152	Dalfopristin RP54476,达福普汀	Antibacterial; Antibiotic	Microbiology/Virology
	Dalfopristin (RP54476) 是一种半合成的链霉素抗生素。 Quinupristin/Dalfopristin (Q/D) 用于治疗耐多药粪肠球菌感染。
TN1296	5-Feruloylquinic acid 5-O-Feruloylquinic acid,5-FQA,5-O-阿魏酰奎尼酸	Tyrosinase; Sirtuin	Chromatin/Epigenetic; DNA Damage/DNA Repair; Proteases/Proteasome
	5-Feruloylquinic acid (5-FQA) 表现出抗氧化作用和酪氨酸酶抑制作用。
T3021	Bulleyaconitine A 草乌甲素,Bulleyaconi cine A	Sodium Channel	Membrane transporter/Ion channel
	Bulleyaconitine A (Bulleyaconi cine A) 是一种分离自乌头属植物的抗炎活性化合物，也可用于缓解疼痛的研究。
T5132	9-dihydro-13-acetylbaccatin III 13-乙酰基-9-羟基巴卡丁 III,13-Acetyl-9-dihydrobaccatin III,9-DHAB III	Apoptosis	Apoptosis
	9-dihydro-13-acetylbaccatin III (9-DHAB III) 是一种制备紫杉醇类似物的中间体。
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天然产物

Allopurinol riboside

Cat.No: T13539

Target: Others, Endogenous Metabolite, Parasite, Drug Metabolite

Isonicotinic acid

Cat.No: Fr13756

Target: Endogenous Metabolite, Drug Metabolite

Cat.No: T8115

Target: Others

Cat.No: TN4660

Target: Anti-infection, HBV, PAFR, Topoisomerase

Cat.No: TN6512

Target: Transferase, Parasite

Homoeriodictyol

Cat.No: TN1740

Synonym: 高胜草酚,高圣草酚

Target: 5-HT Receptor, transporter, Sodium Channel, Drug Metabolite

Docosanedioic acid

Cat.No: T9784

Target: PROTAC Linker, ADC Linker

Cat.No: T8175

Synonym: Laudanosine,DL-劳丹素

Target: Others, Drug Metabolite

Monomethyl fumarate

Cat.No: T12095

Target: GPR, Drug Metabolite

Cat.No: T4820

Synonym: 马来酰亚胺,2,5-Pyrroledione

Target: Others

Cat.No: T4000

Synonym: Equol,(±)-雌马酚,(R,S)-Equol

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Drug Metabolite

Fosfomycin sodium

Cat.No: T8262

Synonym: Fosfomycin Disodium,磷霉素钠

Target: Antibacterial, Antibiotic

Homovanillyl alcohol

Cat.No: TN1742

Synonym: 高香草醇,4-羟基-3-甲氧基苯乙醇

Target: TNF, Drug Metabolite

Cat.No: T2149

Synonym: Eburnalritardo,L-Eburnamonine,长春布宁,Vincamone,(-)-Eburnamonine,(-)-Vincamone

Target: Others, Drug Metabolite

Dobutamine hydrochloride

Cat.No: T8149

Synonym: 盐酸多巴酚丁胺,Dobutamine (hydrochloride)

Target: Adrenergic Receptor

Norgestimate metabolite Norelgestromin

Cat.No: T16338

Synonym: 17-Deacetyl norgestimate,17-Deacylnorgestimate,甲基孕酮

Target: Drug Metabolite

Cat.No: T7174

Synonym: 尿石素A,3,8-二羟基-6H-二苯并[B,D]吡喃-6-酮

Target: Apoptosis, Reactive Oxygen Species, DNA/RNA Synthesis, Endogenous Metabolite, Autophagy, Drug Metabolite

Mycophenolate Mofetil

Cat.No: T6293

Synonym: TM-MMF,吗替麦考酚酯,RS 61443

Target: Apoptosis, Dehydrogenase, Drug Metabolite

Cat.No: T8183

Synonym: 洋地黄,去乙酰西地兰,Desacetyllanatoside C,Deacetyllanatoside C

Target: ATPase, Drug Metabolite

Cat.No: T0983

Synonym: 青霉胺,d-penicillamin,Dimethyl Cysteine,D-青霉胺,Artamine,D-(-)-Penicillamine

Target: Antibiotic

Nicotinamide N-oxide

Cat.No: T0617

Synonym: Nicotinamide-N-oxide,Nicotinamide 1-oxide,N-氧代烟酰胺,烟酰胺-N-氧化物,1-oxynicotinamide

Target: c-Myc, Endogenous Metabolite, CXCR, Drug Metabolite

3-Methoxytyramine hydrochloride

Cat.No: T4710

Synonym: 3-O-methyl Dopamine hydrochloride,3-O-methyl Dopamine hydrochloride),3-O-甲基多巴胺盐酸盐

Target: Others, Endogenous Metabolite, Drug Metabolite

Cat.No: T5320

Synonym: α-methylene-γ-butyrolactone,2-Methylenebutyrolactone,2-甲烯基丁内酯

Target: Others, Drug Metabolite

Cat.No: T17143

Synonym: 丰加霉素,Vengicide

Target: Apoptosis, Others, IRE1, Antibiotic, Antifungal

p-Coumaric Acid Ethyl Ester

Cat.No: T13808

Synonym: 对香豆酸乙酯,Ethyl (E)-p-hydroxycinnamate,Ethyl trans-4-hydroxycinnamate

Target: Others, Drug Metabolite

Cat.No: T3797

Synonym: Isosilybinin,Isosilibinin,异水飞蓟宾,Silymarin,Silybin B,Q-100795

Target: P450

Cat.No: T3212

Synonym: 地谷新配基,异羟基洋地黄毒苷元

Target: Others

Cat.No: T3669

Synonym: (+)-Curcumenol,莪术醇

Target: P450

Cat.No: TWO2771

Synonym: 2-金刚烷醇,Adamantan-2-Ol,2-Hydroxyadamantane

Target: Others

Cat.No: T1468

Synonym: Ro 13-9297,Chlortenoxicam,TS110,氯诺昔康

Target: COX, Endogenous Metabolite

Cat.No: T3327

Synonym: SM-227,β-Arteether,Beta-Arteether,蒿乙醚,Arteether,(+)-Arteether

Target: CXCR, CCR, Parasite

Alisol A 24-acetate

Cat.No: T6S2243

Synonym: Alisol A 24-monoacetate,Alisol A monoacetate,泽泻醇A24-醋酸酯

Target: Others

Tetradecanedioic acid

Cat.No: T5567

Synonym: 十四烷二酸,Tetradecanedicarboxylate

Target: Others, Endogenous Metabolite

Cat.No: T3820

Synonym: 野鸢尾苷,Lridin

Target: Others

4-Hydroxymephenytoin

Cat.No: T10147

Synonym: (+/-)-4'-Hydroxymephenytoin

Target: Others, Drug Metabolite

Cat.No: T7936

Target: Others

Cat.No: T0681

Synonym: Rifamycin AMP,利福平,Rimactane,Rifampin

Target: Influenza Virus, DNA/RNA Synthesis, Antibacterial, Antibiotic, Antifection

Cat.No: T4S0647

Synonym: 丁基苯酞,3-Butylphthalide,3-n-Butylphathlide,3-n-Butylphthalide

Target: Others

Ginsenoside Rh2

Cat.No: T2959

Synonym: 20(S)-Rh2,20S-Ginsenoside Rh2,人参皂苷Rh2,20(S)-Ginsenoside Rh2,人参皂苷 Rh2

Target: Apoptosis, EGFR, Caspase, Endogenous Metabolite

Milbemycin oxime

Cat.No: T1381

Target: Others, Antibiotic, Parasite

Cyanosafracin B

Cat.No: T22286

Synonym: Cyanoquinonamine,氰基番红菌素 B,CBR28-1

Target: Others

Cat.No: T0254

Synonym: DH-581,普罗布考

Target: Virus Protease, ABC, Lipid

Coptisine sulfate

Cat.No: T4S0051

Target: Indoleamine 2,3-Dioxygenase (IDO)

Cat.No: T3S2381

Synonym: 3-Isohexenylfuran,紫苏烯,Perillen

Target: Others, Antibacterial

Anethole trithione

Cat.No: T1285

Synonym: 茴三硫,Anetholtrithion

Target: Others, AChR

Epieriocalyxin A

Cat.No: TN3967

Target: ERK, BCL, ROS, Caspase, DNA/RNA Synthesis, JNK

Cat.No: TQ0152

Synonym: RP54476,达福普汀

Target: Antibacterial, Antibiotic

5-Feruloylquinic acid

Cat.No: TN1296

Synonym: 5-O-Feruloylquinic acid,5-FQA,5-O-阿魏酰奎尼酸

Target: Tyrosinase, Sirtuin

Bulleyaconitine A

Cat.No: T3021

Synonym: 草乌甲素,Bulleyaconi cine A

Target: Sodium Channel

9-dihydro-13-acetylbaccatin III

Cat.No: T5132

Synonym: 13-乙酰基-9-羟基巴卡丁 III,13-Acetyl-9-dihydrobaccatin III,9-DHAB III

Target: Apoptosis

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02062	SULT1A1 Protein, Human, Recombinant (His) HAST1/HAST2,PST,P-PST,ST1A1,STP,sulfotransferase family, cyt...	Human	E. coli
	Sulfate conjugation catalyzed by cytosolic sulfotransferase (SULT) enzymes. The SULTs are Phase II drug-metabolizing enzymes that catalyze the addition of a sulfuryl moiety to both endogenous compounds, including steroids and neurotransmitters, and certain xenobiotics, including N-hydroxy-2-acetylaminoflourine and phenolic compounds, like alpha-naphthol. SULTs may be involved in the individual genetic disposition, species differences, and organotropisms for toxicological effects of chemicals. Pa...
TMPY-05321	CYP3A4 Protein, Human, Recombinant (His) P450C3,P450PCN1,CYPIIIA4,CP34,cytochrome P450 family 3 subfa...	Human	E. coli
	CYP3A4 is an important member of the cytochrome P450 enzyme superfamily, with 33 allelic variants. Human cytochrome P450 3A4 (CYP3A4) is an important drug metabolizing enzyme involved in a number of drug-drug and food-drug interactions. Systemic inflammation has been linked to suppressed CYP3A4 activity.
TMPY-02271	TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His) thioredoxin reductase 1,TR1,TXNR,TR,TRXR1,GRIM-12	Human	E. coli
	Thioredoxin reductase 1 (TXNRD1) which is a selenocysteine-containing protein is overexpressed in many malignancies. TXNRD1 plays a key role in regulating cell growth and transformation, and protects cells against oxidative damage. We investigated the association between TXNRD1 polymorphisms and ATDH susceptibility. Moreover, TXNRD1 is an essential selenium-containing enzyme involved in detoxification of reactive oxygen species (ROS) and redox signaling. And genetic variations in TXNRD1 favor th...
TMPH-03139	MDR1 Protein, Plasmodium falciparum, Recombinant (His & SUMO) Chloroquine resistance protein,MDR1,Multidrug resis...	Plasmodium falciparum	E. coli
	Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. MDR1 Protein, Plasmodium falciparum, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 54.2 kDa and the accession number is P13568.
TMPK-01308	TAG-72 Protein, Canine, Recombinant (His) mRNA-methyltransferase,mRNA (guanine-N(7))-methyltransferase...	Canine	E. coli
	The guanine-N7 methyltransferase domain of vaccinia virus mRNA capping enzyme is a heterodimer composed of a catalytic subunit and a stimulatory subunit. Cap (guanine-N7) methylation is an essential step in eukaryal mRNA synthesis and a potential target for antiviral, antifungal, and antiprotozoal drug discovery.
TMPK-00806	GHR/Growth Hormone R Protein, Human, Recombinant (His) GHR/BP,GH receptor,GHBP,GHR	Human	HEK293 Cells
	Pegvisomant, a growth hormone receptor (GHR) antagonist, is a well-known drug that was designed to treat acromegaly. However, recent studies have indicated that the GHR is a "moonlighting" protein that may exhibit dual functions based on its localization in the plasma membrane and nucleus.
TMPK-01039	FcRH5/FcRL5 Protein, Mouse, Recombinant (His) CD307e,FcRL5,BXMAS1MGC119592,IFGP5,FcRH5,BXMAS1,CD307,DKFZp6...	Mouse	HEK293 Cells
	FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. FcRH5/FcRL5 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 53.7 kDa and the accession number is Q68SN8-1.
TMPK-00759	IgG1 Fc Protein, Human, Recombinant Igh-4,VH7183,IgG1,RGD1359539	Human	HEK293 Cells
	IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR) on phagocytic cells with high affinity. Fc fragment is demonstrated to mediate phagocytosis, trigger inflammation, and target Ig to particular tissues.IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
TMPK-00618	FcRH5/FcRL5 Protein, Human, Recombinant (His) FcR-like protein 5,CD307,BXMAS1,FcRH5,IFGP5,CD307e,FcRL5	Human	HEK293 Cells
	FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. FcRH5/FcRL5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 92.38 kDa and the accession number is AAK93971.
TMPK-01145	FcRH5/FcRL5 Protein, Human, Recombinant (His & Avi), Biotinylated CD307,FcRL5,FcR-like protein 5,FCRH5MGC119593,DKFZp667F216,B...	Human	HEK293 Cells
	FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. FcRH5/FcRL5 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 94.19 kDa and the accession number is Q96RD9-1.
TMPK-00619	FcRH5/FcRL5 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated IFGP5,CD307,FCRH5MGC119593,FLJ00397,DKFZp667E2019,BXMAS1MGC1...	Human	HEK293 Cells
	FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. FcRH5/FcRL5 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 92.38 kDa and the accession number is AAK93971.
TMPK-00483	PCSK9 Protein, Cynomolgus, Recombinant (His) PCSK9	Cynomolgus	HEK293 Cells
	Proprotein convertase subtilisin/kexin type 9 (PCSK9) is an enzyme encoded by the PCSK9 gene in humans on chromosome 1.The first two PCSK9 inhibitors, alirocumab and evolocumab, were approved as once every two week injections, by the U.S. Food and Drug Administration in 2015 for lowering LDL-particle concentrations when statins and other drugs were not sufficiently effective or poorly tolerated.
TMPJ-01426	SARS-CoV-2 NSP2 Protein (His) SARS-CoV 2 nsp2,SARS-CoV 2 p65 homolog	SARS-CoV-2	E. coli
	The positive-stranded RNA genome of the coronaviruses is translated from ORF1 to yield polyproteins that are proteolytically processed into intermediate and mature nonstructural proteins (nsps). SARS-CoV 2 polyproteins incorporate 16 protein domains (nsps). The putative non-structural protein 2 (nsp2) of SARS-CoV plays an important role in viral transcription and replication, and is an attractive target for anti-SARS drug development.
TMPK-00407	AXL Protein, Human, Recombinant (His & Avi) AXL oncogene,Axl,EC 2.7.10.1,Tyro7,UFO,ARK,EC 2.7.10,AI32364...	Human	HEK293 Cells
	Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers. AXL Protein, Human, Recombinant (His & Avi) is e...
TMPK-01384	SARS PLpro/papain-like protease Protein (His) Papain-like Protease,PL-PRO,Replicase polyprotein 1a,pp1a,PL...	SARS	E. coli
	The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro and 3CLpro are to process the viral polyprotein in a coordinated manner, PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses. SARS PLpro/papain-like protease Protein (...
TMPK-00472	AXL Protein, Cynomolgus, Recombinant (His) Tyro7,JTK11,AI323647,AXL oncogene,EC 2.7.10.1,EC 2.7.10,UFO,...	Cynomolgus	HEK293 Cells
	Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers. AXL Protein, Cynomolgus, Recombinant (His) is ex...
TMPY-03458	Sorcin/SRI Protein, Human, Recombinant sorcin,SCN,CP22,V19,CP-22	Human	Baculovirus Insect Cells
	Sorcin was originally identified in multidrug-resistant cells. It is a calcium-binding protein. Sorcin modulates excitation-contraction coupling in the heart, contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Sorcin is overexpressed in the multi-drug resistant chinese hamster ovary cell line CHRC5 and a variety of multidrug-resistant tumor cell lines, but overexpression is not a sufficient or necessary condition for the acquisition of the multidrug-resistant phenotype. Sorc...
TMPK-00954	Hyaluronidase 2/HYAL2 Protein, Human, Recombinant (His) LuCa-2,Hyaluronidase 2,LUCA2,HYAL2,Hyal-2,Hyaluronidase-2	Human	HEK293 Cells
	Hyaluronidases, a family of enzymes that are able to degrade hyaluronic acid (HA), are employed in medicine to increase drug diffusion and reverse the effects of HA filler injections. Hyaluronidases are able to dissolve subcutaneous nodules or to correct excessive quantities of injected filler. Upregulation of hyaluronidase 2 (HYAL2), one of somatic hyaluronidase (HAase), was demonstrated in granulation tissue during the healing of equine superficial digital flexor tendon injuries. Hyaluronidase...
TMPK-00410	AXL Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated ARK,EC 2.7.10.1,EC 2.7.10,Axl,JTK11,AXL oncogene,UFO,AI32364...	Human	HEK293 Cells
	Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers. AXL Protein (Primary Amine Labeling), Human, Rec...
TMPY-02442	ELK1 Protein, Human, Recombinant (His & GST) ELK1, member of ETS oncogene family	Human	Baculovirus Insect Cells
	E twenty-six (ETS)-like transcription factor 1, also known as Elk1 or Member of ETS oncogene family (ELK1), is a member of the ETS oncogene superfamily which is characterized by a common protein domain that regulates DNA binding to target sequences. Elk1 is expressed in the nuclei of non-neuronal cells and function as a transcription activator. It plays important roles in various contexts, including long-term memory formation, drug addiction, Alzheimer's disease, Down syndrome, breast cancer, an...
TMPK-01158	Kallikrein 5/KLK5 Protein, Mouse, Recombinant (His) SCTE,KLKL2,KLK5,KLK-L2,Klnc,Kallikrein c	Mouse	HEK293 Cells
	The inhibition of kallikrein 5 (KLK5) has been identified as a potential strategy for treatment of the genetic skin disorder Netherton syndrome, in which loss-of-function mutations in the SPINK5 gene lead to down-regulation of the endogenous inhibitor LEKTI-1 and profound skin-barrier defects with severe allergic manifestations. To aid in the development of a medicine for this target, an X-ray crystallographic system was developed to facilitate fragment-guided chemistry and knowledge-based drug-...
TMPK-00725	Hyaluronidase 2/HYAL2 Protein, Mouse, Recombinant (His) Hyaluronidase-2,Hyal-2,Hyaluronidase 2,HYAL2	Mouse	HEK293 Cells
	Hyaluronidases, a family of enzymes that are able to degrade hyaluronic acid (HA), are employed in medicine to increase drug diffusion and reverse the effects of HA filler injections. Hyaluronidases are able to dissolve subcutaneous nodules or to correct excessive quantities of injected filler. Upregulation of hyaluronidase 2 (HYAL2), one of somatic hyaluronidase (HAase), was demonstrated in granulation tissue during the healing of equine superficial digital flexor tendon injuries. Hyaluronidase...
TMPK-00408	AXL Protein, Human, Recombinant (His & Avi), Biotinylated AXL oncogene,EC 2.7.10.1,AI323647,Axl,JTK11,ARK,EC 2.7.10,UF...	Human	HEK293 Cells
	Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers. AXL Protein, Human, Recombinant (His & Avi), Bio...
TMPK-00875	CD96 Protein, Human, Recombinant (His & Avi), Biotinylated TACTILE,CD96,DKFZp667E2122,CD96 molecule	Human	HEK293 Cells
	The receptors CD96 and TIGIT are expressed on the surface of T and natural killer (NK) cells, and recent studies suggest both play important inhibitory roles in immune function. CD96 has been shown to modulate immune cell activity in mice, with Cd96-/- mice displaying hypersensitive NK-cell responses to immune challenge and significant tumor resistance. The counterbalance between the putative inhibitory CD96 and TIGIT receptors and the activating receptor, CD226, offers unique strategies for imm...
TMPY-03267	Sorcin/SRI Protein, Human, Recombinant (His & GST) CP-22,CP22,sorcin,V19,SCN	Human	Baculovirus Insect Cells
	Sorcin was originally identified in multidrug-resistant cells. It is a calcium-binding protein. Sorcin modulates excitation-contraction coupling in the heart, contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Sorcin is overexpressed in the multi-drug resistant chinese hamster ovary cell line CHRC5 and a variety of multidrug-resistant tumor cell lines, but overexpression is not a sufficient or necessary condition for the acquisition of the multidrug-resistant phenotype. Sorc...
TMPK-01352	SARS-CoV-2 PLpro/papain-like protease Protein (His & Avi) Plpro,PL2-PRO,pp1a,nsp1,Replicase polyprotein 1a,Papain-like...	SARS	E. coli
	The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro and 3CLpro are to process the viral polyprotein in a coordinated manner, PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses. SARS-CoV-2 PLpro/papain-like protease Pro...
TMPY-06864	GLP1R Protein, Human, Recombinant (His & Avi) glucagon-like peptide 1 receptor	Human	HEK293 Cells
	Glucagon-like peptide (GLP)-1 receptor is encoded by GLP1R. GLP1R plays a critical role in mediating the biological actions of GLP1 in mammals and fish. The neuronal GLP1Rs mediate body weight and anorectic effects of liraglutide, but are not required for glucose-lowering effects. Glucagon-like peptide 1 receptor (GLP1R) signaling has been shown to have antipsychotic properties in animal models and to impact glucose-dependent insulin release, satiety, memory, and learning in man. Glucagon-like p...
TMPJ-01145	ABCB5 Protein, Human, Recombinant (Trx) ABCB5 P-gp,ATP-binding cassette sub-family B member 5,ABCB5,...	Human	E. coli
	ATP-binding cassette sub-family B member 5(ABCB5) is a plasma membrane-spanning protein. ABCB5 is principally expressed in physiological skin and human malignant melanoma. ABCB5 has been suggested to regulate skin progenitor cell fusion and mediate chemotherapeutic drug resistance in stem-like tumor cell subpopulations in human malignant melanoma. It is commonly over-expressed on circulating melanoma tumour cells. Furthermore, the ABCB5+ melanoma- initiating cells were demonstrated to express FL...
TMPY-03416	TNFAIP8 Protein, Human, Recombinant (His) GG2-1,tumor necrosis factor, alpha-induced protein 8,SCCS2,S...	Human	E. coli
	Tumor necrosis factor (TNF)-alpha-induced protein 8 (TNFAIP8) family is a newly identified protein with vital roles in maintaining immune homeostasis. Tumor necrosis factor-alpha-inducible protein 8 (TNFAIP8) is a TNF-alpha inducible anti-apoptotic protein with multiple roles in tumor growth and survival. by the creation of cellular autophagy events, TNFAIP8 promotes cell survival and drug resistance in prostate cancer cells. TNFAIP8 regulates Hippo pathway through interacting with LATS1 to prom...
TMPJ-00295	NgR Protein, Mouse, Recombinant (hFc) Nogo-66 Receptor,Nogo Receptor,NgR,RTN4R,NOGOR,Reticulon-4 R...	Mouse	HEK293 Cells
	Nogo Receptor (NgR) is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family. Human NgR is predominantly expressed in neurons and their axons in the central nervous systems. As a receptor for myelin-derived proteins Nogo, myelin-associated glycoprotein (MAG) and myelin oligodendrocyte glycoprotein (OMG), NgR mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. NgR may be prop...
TMPJ-00922	DCK Protein, Human, Recombinant (His & T7) DCK,Deoxycytidine Kinase	Human	E. coli
	Deoxycytidine Kinase (DCK) is a member of the DCK/DGK family. DCK exists as a homodimer and is localized to the nucleus. DCK is required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG), and deoxyadenosine (dA). DCK has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. In addition, DCK is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and c...
TMPY-00648	UNC5A Protein, Human, Recombinant (hFc) UNC5H1,unc-5 homolog A (C. elegans)	Human	HEK293 Cells
	The netrin-1 receptor Uncoordinated Phenotype-5A, or UNC5A, plays an important role in predicting response to DNA damage induced by chemotherapeutic drug and regulating cell death in bladder cancer. Moreover, UNC5A is cumulatively downregulated by the unfolding protein response (UPR) at the transcriptional level in vitro and at the translational level both in vitro and in vivo. Also, UNC5A is a novel transcriptional target of p53 and plays a role in p53-dependent apoptosis. UNC5A Protein, Human,...
TMPY-00999	UNC5A Protein, Human, Recombinant (His) unc-5 homolog A (C. elegans),UNC5H1	Human	HEK293 Cells
	The netrin-1 receptor Uncoordinated Phenotype-5A, or UNC5A, plays an important role in predicting response to DNA damage induced by chemotherapeutic drug and regulating cell death in bladder cancer. Moreover, UNC5A is cumulatively downregulated by the unfolding protein response (UPR) at the transcriptional level in vitro and at the translational level both in vitro and in vivo. Also, UNC5A is a novel transcriptional target of p53 and plays a role in p53-dependent apoptosis. UNC5A Protein, Human,...
TMPJ-01037	CXCR4 Protein, Human, Recombinant (hFc) CXCR4,CD184,Fusin,D2S201E,FB22,HM89,HSY3RR,LAP3,LCR1,LESTR,N...	Human	HEK293 Cells
	C-X-C chemokine receptor type 4 (CXCR4) is an alpha-chemokine receptor specific for stromal-derived-factor-1 (SDF-1 also called CXCL12), a molecule endowed with potent chemotactic activity for lymphocytes. This receptor is one of several chemokine receptors that HIV isolates can use to infect CD4+ T cells. CXCR4 stands out for its pleiotropic roles in both physiological and pathological conditions and it represents a crucial target in drug development. CXCL12 is the principal CXCR4 specific liga...
TMPY-02394	IMPA1 Protein, Human, Recombinant (His) IMPA,inositol(myo)-1(or 4)-monophosphatase 1,IMP	Human	E. coli
	IMPA1 (Inositol Monophosphatase 1) is a Protein Coding gene. This gene encodes an enzyme that dephosphorylates Myo-inositol monophosphate to generate free Myo-inositol, a precursor of phosphatidylinositol, and is, therefore, an important modulator of intracellular signal transduction via the production of the second messenger's myoinositol 1,4,5-trisphosphate and diacylglycerol. Despite its many physiological functions, no clinical phenotype has been assigned to this gene dysfunction to date. Ad...
TMPY-02909	ASGR2 Protein, Human, Recombinant (His) HBXBP,ASGPR2,HL-2,asialoglycoprotein receptor 2,ASGP-R2,CLEC...	Human	HEK293 Cells
	ASGR2 is a subunit of the asialoglycoprotein receptor. Asialoglycoprotein receptor, also known as the Ashwell receptor, which is specific for desialylated (galactosyl-terminal) glycoproteins and is expressed exclusively in hepatic parenchymal cells. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. ASGR2 is ...
TMPY-05693	SARS-CoV-2 Methyltransferase/ME Protein (His)	SARS-CoV-2	E. coli
	Coronavirus encodes the 2’-O-MTase (2'O Methyltransferase) that is composed of the catalytic subunit nsp16 and the stimulatory subunit nsp10 and plays an important role in virus genome replication and evasion from innate immunity during viral infection. Nonstructural protein 16 (NSP16) / viral 2'O-methyltransferase (2'O-MTase) is highly conserved. The conserved 2'O-MTase activity is important for CoV pathogenesis and NSP16 is a conserved universal target for rapid live attenuated vaccine design ...
TMPY-06836	NR3C1 Protein, Human, Recombinant (His) GCCR,GRL,GR,nuclear receptor subfamily 3, group C, member 1 ...	Human	E. coli
	NR3C1 (Nuclear Receptor Subfamily 3 Group C Member 1) is a Protein Coding gene. This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. NR3C1 is a transcriptional regulator of many drug-metabolizing enzymes and anti-inflammatory molecules. NR3C1 polymorphisms associate with obesi...
TMPJ-01028	Claudin-18.2 Protein, Human, Recombinant (Twin strep & Flag) Claudin 18.2,CLDN18,Claudin-18,CLDN18.2,Claudin-18.2	Human	HEK293 Cells
	Claudin-18 (CLDN18) is a protein that in humans is encoded by the CLDN18 gene. It belongs to the group of claudins. CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. CLDN18 plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. CLDN18 has two isoform A1 and isoform A2. Human CLDN18.2 is highly expressed in a signifcant proportion of gastric and pancreat...
TMPY-02081	PDE2A Protein, Human, Recombinant (aa 215-900, His) phosphodiesterase 2A, cGMP-stimulated,cGSPDE,PED2A4,PDE2A1,C...	Human	Baculovirus Insect Cells
	cGMP-dependent 3',5'-cyclic phosphodiesterase, also known as cyclic GMP-stimulated phosphodiesterase and PDE2A, is a peripheral membrane protein that belongs to the cyclic nucleotide phosphodiesterase family and PDE2 subfamily. Phosphodiesterases (PDEs) comprise a family of enzymes that regulate the levels of cyclic nucleotides, key second messengers that mediate a diverse array of functions. Phosphodiesterases (PDEs) modulate signaling by cyclic nucleotides in diverse processes such as cardiac ...
TMPY-01099	GPT Protein, Rat, Recombinant (His) Gpt1,ALAT,glutamic-pyruvate transaminase (alanine aminotrans...	Rat	Baculovirus Insect Cells
	Alanine aminotransferase (ALT), also known as glutamate pyruvate transaminase (GPT), is a pyridoxal enzyme that belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family, Alanine aminotransferase subfamily. Gpt / Gpt1 / ALT catalyzes the reversible interconversion of L-alanine and 2-oxoglutalate to pyruvate and L-glutamate and plays a key role in the intermediary metabolism of glucose and amino acids. Gpt / Gpt1 / ALT is expressed in the liver, kidney, heart, and skeletal musc...
TMPJ-00751	IgG4 hFc Protein, Human, Recombinant (aa 99-326) IgG4 Fc,Ig γ-4 chain C region,Ig gamma-4 chain C region	Human	HEK293 Cells
	As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma B cells, and constitutes 75% of serum immunoglobulins in humans. IgG antibodies protect the body against the pathogens by agglutination and immobilization, complement activation, toxin neutralization, as well as the antibody-dependent cell-mediated cytotoxicity (ADCC). IgG tetram...
TMPY-01893	Serpin A12 Protein, Human, Recombinant (His) OL-64,serpin peptidase inhibitor, clade A (α-1 antiproteinas...	Human	HEK293 Cells
	Serpins are the largest and most diverse family of protease inhibitors. Most serpins control proteolytic cascades, certain serpins do not inhibit enzymes, but instead perform diverse functions such as storage (ovalbumin, in egg white), hormone carriage proteins (thyroxine-binding globulin, cortisol-binding globulin) and tumor suppressor genes (maspin). Most inhibitory serpins target chymotrypsin-like serine proteases. These enzymes are defined by the presence of a nucleophilic serine residue in ...
TMPY-02072	HSF1 Protein, Human, Recombinant (His) HSTF1,heat shock transcription factor 1	Human	E. coli
	Heat shock factor protein 1, also known as heat shock transcription factor 1, HSF1, and HSTF1, is a cytoplasm and nucleus protein that belongs to the HSF family. HSF1 is the major transcription factor of HSPs (heat shock proteins) in response to various stresses. Wild type HSF1 (heat shock transcriptional factor 1) is normally inactive. HSF1 / HSTF1 is a DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable...
TMPY-01742	Acetylcholinesterase Protein, Mouse, Recombinant (His) Acre,Chrne,acetylcholinesterase (Yt blood group)	Mouse	HEK293 Cells
	Acetylcholinesterase, also known as ACHE, is an enzyme that degrades (through its hydrolytic activity) the neurotransmitter acetylcholine, producing choline and an acetate group. Acetylcholinesterase plays a crucial role in nerve impulse transmission at cholinergic synapses by rapid hydrolysis of the neurotransmitter acetylcholine (ACh). ACHE appears to be a potential therapeutic target at muscle injuries including organophosphate myopathy. It is an externally oriented membrane-bound enzyme and ...
TMPY-02150	GADD45A Protein, Human, Recombinant (His & GST) GADD45,growth arrest and DNA-damage-inducible, alpha,growth ...	Human	Baculovirus Insect Cells
	GADD45A is a member of the GADD45 Family, and has been found to associate with several cytoplasmic and nuclear factors and has been implicated in several cellular functions, including MAPK signaling, cell cycle regulation, DNA repair and genomic stability, apoptosis, and immune responses. The GADD45 Family of genes is rapidly induced by different stressors, including differentiation-inducing cytokines, and there is a large body of evidence that their cognate proteins are key players in cellular ...
TMPY-01576	Artemin Protein, Mouse, Recombinant (hFc) artemin,neublastin	Mouse	HEK293 Cells
	Artemin (ARTN) is a member of glial cell line-derived neurotrophic factor (GDNF) family of ligands, and its signaling is mediated via a multi-component receptor complex including the glycosylphosphatidylinositol-anchored GDNF family receptors a (GFRa1, GFRa3) and RET receptor tyrosine kinase. The major mechanism of ARTN action is via binding to a non-signaling co-receptor. The major function of ARTN is to drive the molecule to induce migration and axonal projection from sympathetic neurons. It a...

重组蛋白

SULT1A1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02062

Species: Human

Expression System: E. coli

CYP3A4 Protein, Human, Recombinant (His)

Cat.No: TMPY-05321

Species: Human

Expression System: E. coli

TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His)

Cat.No: TMPY-02271

Species: Human

Expression System: E. coli

MDR1 Protein, Plasmodium falciparum, Recombinant (His & SUMO)

Cat.No: TMPH-03139

Species: Plasmodium falciparum

Expression System: E. coli

TAG-72 Protein, Canine, Recombinant (His)

Cat.No: TMPK-01308

Species: Canine

Expression System: E. coli

GHR/Growth Hormone R Protein, Human, Recombinant (His)

Cat.No: TMPK-00806

Species: Human

Expression System: HEK293 Cells

FcRH5/FcRL5 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-01039

Species: Mouse

Expression System: HEK293 Cells

IgG1 Fc Protein, Human, Recombinant

Cat.No: TMPK-00759

Species: Human

Expression System: HEK293 Cells

FcRH5/FcRL5 Protein, Human, Recombinant (His)

Cat.No: TMPK-00618

Species: Human

Expression System: HEK293 Cells

FcRH5/FcRL5 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-01145

Species: Human

Expression System: HEK293 Cells

FcRH5/FcRL5 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

Cat.No: TMPK-00619

Species: Human

Expression System: HEK293 Cells

PCSK9 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00483

Species: Cynomolgus

Expression System: HEK293 Cells

SARS-CoV-2 NSP2 Protein (His)

Cat.No: TMPJ-01426

Species: SARS-CoV-2

Expression System: E. coli

AXL Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00407

Species: Human

Expression System: HEK293 Cells

SARS PLpro/papain-like protease Protein (His)

Cat.No: TMPK-01384

Species: SARS

Expression System: E. coli

AXL Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00472

Species: Cynomolgus

Expression System: HEK293 Cells

Sorcin/SRI Protein, Human, Recombinant

Cat.No: TMPY-03458

Species: Human

Expression System: Baculovirus Insect Cells

Hyaluronidase 2/HYAL2 Protein, Human, Recombinant (His)

Cat.No: TMPK-00954

Species: Human

Expression System: HEK293 Cells

AXL Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated

Cat.No: TMPK-00410

Species: Human

Expression System: HEK293 Cells

ELK1 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-02442

Species: Human

Expression System: Baculovirus Insect Cells

Kallikrein 5/KLK5 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-01158

Species: Mouse

Expression System: HEK293 Cells

Hyaluronidase 2/HYAL2 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00725

Species: Mouse

Expression System: HEK293 Cells

AXL Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00408

Species: Human

Expression System: HEK293 Cells

CD96 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00875

Species: Human

Expression System: HEK293 Cells

Sorcin/SRI Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-03267

Species: Human

Expression System: Baculovirus Insect Cells

SARS-CoV-2 PLpro/papain-like protease Protein (His & Avi)

Cat.No: TMPK-01352

Species: SARS

Expression System: E. coli

GLP1R Protein, Human, Recombinant (His & Avi)

Cat.No: TMPY-06864

Species: Human

Expression System: HEK293 Cells

ABCB5 Protein, Human, Recombinant (Trx)

Cat.No: TMPJ-01145

Species: Human

Expression System: E. coli

TNFAIP8 Protein, Human, Recombinant (His)

Cat.No: TMPY-03416

Species: Human

Expression System: E. coli

NgR Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-00295

Species: Mouse

Expression System: HEK293 Cells

DCK Protein, Human, Recombinant (His & T7)

Cat.No: TMPJ-00922

Species: Human

Expression System: E. coli

UNC5A Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00648

Species: Human

Expression System: HEK293 Cells

UNC5A Protein, Human, Recombinant (His)

Cat.No: TMPY-00999

Species: Human

Expression System: HEK293 Cells

CXCR4 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-01037

Species: Human

Expression System: HEK293 Cells

IMPA1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02394

Species: Human

Expression System: E. coli

ASGR2 Protein, Human, Recombinant (His)

Cat.No: TMPY-02909

Species: Human

Expression System: HEK293 Cells

SARS-CoV-2 Methyltransferase/ME Protein (His)

Cat.No: TMPY-05693

Species: SARS-CoV-2

Expression System: E. coli

NR3C1 Protein, Human, Recombinant (His)

Cat.No: TMPY-06836

Species: Human

Expression System: E. coli

Claudin-18.2 Protein, Human, Recombinant (Twin strep & Flag)

Cat.No: TMPJ-01028

Species: Human

Expression System: HEK293 Cells

PDE2A Protein, Human, Recombinant (aa 215-900, His)

Cat.No: TMPY-02081

Species: Human

Expression System: Baculovirus Insect Cells

GPT Protein, Rat, Recombinant (His)

Cat.No: TMPY-01099

Species: Rat

Expression System: Baculovirus Insect Cells

IgG4 hFc Protein, Human, Recombinant (aa 99-326)

Cat.No: TMPJ-00751

Species: Human

Expression System: HEK293 Cells

Serpin A12 Protein, Human, Recombinant (His)

Cat.No: TMPY-01893

Species: Human

Expression System: HEK293 Cells

HSF1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02072

Species: Human

Expression System: E. coli

Acetylcholinesterase Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01742

Species: Mouse

Expression System: HEK293 Cells

GADD45A Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-02150

Species: Human

Expression System: Baculovirus Insect Cells

Artemin Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-01576

Species: Mouse

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
T12411	Perphenazine D8 Dihydrochloride	Others	Others
	Perphenazine D8 Dihydrochloride is the deuterium labeled Perphenazine, which is an antipsychotic drug.
T11891	Lumefantrine-d18 Benflumetol D18,苯芴醇 D18,Lumefantrine D18	Others	Others
	Lumefantrine D18 is an antimalarial drug, and is the deuterium labeled Lumefantrine.
TMIJ-0449	Dimetridazole-d3
	Dimetridazole-d3 是 Dimetridazole 的氘代化合物。Dimetridazole 的 CAS 号为 551-92-8。Dmetridazole 是一种对抗原生动物感染的硝基咪唑类药物。
T40915	L-Aspartic acid 13C
	L-Aspartic acid 13C is a 13C labeled L-Aspartic acid. L-Aspartic acid is is an amino acid, shown to be a suitable prodrug for colon-specific drug deliverly.
T31108	CTP-347 CTP347,CTP 347
	CTP-347, a deuterated version of paroxetine, is potentially the best non-hormonal drug in its class for the treatment of hot flashes.
T12336	Oxaprozin D4 Wy-21743 D4	Others	Others
	Oxaprozin D4 is the deuterium labeled Oxaprozin, is a non-steroidal anti-inflammatory drug (NSAID).
T13155	Tiaprofenic acid D3	Others	Others
	Tiaprofenic acid D3 is a deuterium-labeled Tiaprofenic acid. Tiaprofenic acid is a nonsteroidal anti-inflammatory drug and treatment of rheumatic diseases.
T19183	Albendazole-d3 Albendazole D3	Others	Others
	Albendazole D3 is the deuterium-labeled Albendazole. Albendazole is used as a drug indicated for the treatment of a variety of worm infestations.
TMIJ-0207	(S)-Ketoprofen-d3
	(S)-Ketoprofen-d3 是 (S)-Ketoprofen 的氘代化合物。(S)-Ketoprofen 的 CAS 号为 22161-81-5。S-(+)-Ketoprofen 抑制COX-1和COX-2的IC50值分别为 1.9 和 27 nM。
TMIJ-0037	Sarafloxacin-d8 Hydrochloride
	Sarafloxacin-d8 Hydrochloride 是 Sarafloxacin Hydrochloride 的氘代化合物。Sarafloxacin Hydrochloride 的 CAS 号为 91296-87-6。Sarafloxacin hydrochloride是一种抗菌化合物。
TMIH-0496	Rifampicin-d8
	Rifampicin-d8 是 Rifampicin 的氘代化合物。Rifampicin 的 CAS 号为 13292-46-1。Rifampicin是广谱抗生素，可抵抗细菌病原体以及具有抗流感病毒活性。
TMIH-0494	Rifampicin-d3
	Rifampicin-d3 是 Rifampicin 的氘代化合物。Rifampicin 的 CAS 号为 13292-46-1。Rifampicin是广谱抗生素，可抵抗细菌病原体以及具有抗流感病毒活性。
TMIJ-0298	Flunixin-d3 (methyl-d3)
	Flunixin-d3 (methyl-d3) 是 Flunixin 的氘代化合物。Flunixin 的 CAS 号为 38677-85-9。
TMID-0217	Norfluoxetine-d5 Hydrochloride
	Norfluoxetine-d5 Hydrochloride 是 Norfluoxetine Hydrochloride 的氘代化合物。Norfluoxetine Hydrochloride 的 CAS 号为 57226-68-3。Norfluoxetine Hydrochloride 是氟西汀的活性代谢物。氟西汀是一种抗抑郁药。
TMIJ-0394	Hydroxy Ipronidazole-d3
	Hydroxy Ipronidazole-d3 是 Hydroxy Ipronidazole 的氘代化合物。Hydroxy Ipronidazole 的 CAS 号为 35175-14-5。
TMID-0199	Rifampicin-13C-d3
	Rifampicin-13C-d3 是 Rifampicin 的 13C 和氘代化合物。Rifampicin 的 CAS 号为 13292-46-1。Rifampicin是广谱抗生素，可抵抗细菌病原体以及具有抗流感病毒活性。
T38638	4-Trifluoromethylsalicylic acid-13C6 4-Trifluoromethylsalicylic acid-13C6,Desacetyl triflusal-13C6
	4-Trifluoromethylsalicylic acid-13C6 是 13C 标记的 4-Trifluoromethylsalicylic acid，主要用于药物开发过程中的定量示踪剂。4-Trifluoromethylsalicylic acid 也是一种血小板聚集抑制剂。
TMIH-0130	Butylphthalide-d7 NBP-d7
	Butylphthalide-d7 是 Butylphthalide 的氘代化合物。Butylphthalide 的 CAS 号为 6066-49-5。Butylphthalide 是一种抗脑缺血药物，最初分离自芹菜种中，对中风动物模型有效。
TMIJ-0096	Buspirone EP Impurity A-d8 Buspirone USP Related Compound A-d8
	Buspirone EP Impurity A-d8 是 Buspirone EP Impurity A 的氘代化合物。Buspirone EP Impurity A 的 CAS 号为 20980-22-7。2-(1-Piperazinyl)pyrimidine 用作抗焦虑药。
TMID-0015	Bendazac-d7
	Bendazac-d7 是 Bendazac 的氘代化合物。Bendazac 的 CAS 号为 20187-55-7。Bendazac 是一种氧乙酸，具有抗过敏、抗炎、利胆和抗血脂作用。它能够阻断蛋白质变性，延缓白内障的发生过程。
TMIJ-0105	3-Butylphthalide-d9
	3-Butylphthalide-d9 是 3-Butylphthalide 的氘代化合物。3-Butylphthalide 的 CAS 号为 6066-49-5。Butylphthalide 是一种抗脑缺血药物，最初分离自芹菜种中，对中风动物模型有效。
TMID-0198	Esmolol-d7 HCl
	Esmolol-d7 HCl 是 Esmolol HCl 的氘代化合物。Esmolol HCl 的 CAS 号为 81161-17-3。Esmolol hydrochloride 是一种心脏选择性β受体阻滞剂，用于治疗心律失常和严重高血压。
TMID-0241	Olmesartan-d6 Acid
	Olmesartan-d6 Acid 是 Olmesartan Acid 的氘代化合物。Olmesartan Acid 的 CAS 号为 144689-24-7。Olmesartan 是一种血管紧张素II受体 (AT1R) 拮抗剂，常用于研究高血压。
TMIJ-0102	Ropivacaine-d7
	Ropivacaine-d7 是 Ropivacaine 的氘代化合物。Ropivacaine 的 CAS 号为 84057-95-4。Ropivacaine 是有效的钠通道阻断剂，通过可逆地抑制钠离子内流从而引起神经纤维脉冲传导阻滞。Ropivacaine 也是一种 K2P(双孔钾通道)TREK-1的抑制剂，在 COS-7 细胞膜上的 IC50值为 402.7 μM。Ropivacaine 可以用于神经性疼痛的缓解的相关研究。
TMIJ-0059	Moxifloxacin-d4
	Moxifloxacin-d4 是 Moxifloxacin 的氘代化合物。Moxifloxacin 的 CAS 号为 151096-09-2。Moxifloxacin 是一种8-甲氧基喹诺酮类口服有效抗菌药物，用于急性细菌性鼻窦炎，慢性支气管炎的急性细菌性加重和感染性肺炎的研究。
TMID-0276	MAA-d3
	MAA-d3 是 MAA 的氘代化合物。MAA 的 CAS 号为 519-98-2。4-Methylamino antipyrine 是 Metamizole 的活性代谢产物，可用于疼痛和发烧的研究。Metamizole 是吡唑啉酮类非甾体抗炎药，可抑制COX。
TMIH-0290	Ketorolac-d5-P1
	Ketorolac-d5-P1 是 Ketorolac 的氘代化合物。Ketorolac 的 CAS 号为 74103-06-3。Ketorolac 是非甾体抗炎剂，是非选择性的COX抑制剂，对 COX-1 和 COX-2 的IC50值分别为 20 和 120 nM。
TMIH-0291	Ketorolac-d5-P2
	Ketorolac-d5-P2 是 Ketorolac 的氘代化合物。Ketorolac 的 CAS 号为 74103-06-3。Ketorolac 是非甾体抗炎剂，是非选择性的COX抑制剂，对 COX-1 和 COX-2 的IC50值分别为 20 和 120 nM。
TMIH-0024	10,11-Dihydro-10-hydroxycarbamazepine-d4 rac-Licarbazepine-d4
	10,11-Dihydro-10-hydroxycarbamazepine-d4 是 10,11-Dihydro-10-hydroxycarbamazepine 的氘代化合物。10,11-Dihydro-10-hydroxycarbamazepine 的 CAS 号为 29331-92-8。Licarbazepine 是一种有效的电压门控钠通道阻滞剂，具有抗惊厥和稳定情绪的功效。
TMIJ-0079	N-Carbobenzyloxyglycine-d2
	N-Carbobenzyloxyglycine-d2 是 N-Carbobenzyloxyglycine 的氘代化合物。N-Carbobenzyloxyglycine 的 CAS 号为 1138-80-3。Z-Glycine (Carbobenzoxyglycine) 是一种药物-脂质结合物，旨在促进脑渗透，基于其亲脂性和与生物膜中脂质的相似性。
TMIJ-0335	Dehydro aripiprazole-d8
	Dehydro aripiprazole-d8 是 Dehydro aripiprazole 的氘代化合物。Dehydro aripiprazole 的 CAS 号为 129722-25-4。Dehydroaripiprazole 是 Aripiprazole 的活性代谢产物，具有抗精神病活性。Aripiprazole 是也一种抗精神病药。
TMID-0185	(±)-Ropivacaine-d7
	(±)-Ropivacaine-d7 是 (±)-Ropivacaine 的氘代化合物。(±)-Ropivacaine 的 CAS 号为 84057-95-4。Ropivacaine 是有效的钠通道阻断剂，通过可逆地抑制钠离子内流从而引起神经纤维脉冲传导阻滞。Ropivacaine 也是一种 K2P(双孔钾通道)TREK-1的抑制剂，在 COS-7 细胞膜上的 IC50值为 402.7 μM。Ropivacaine 可以用于神经性疼痛的缓解的相关研究。
TMID-0281	Moxifloxacin-13C-d3
	Moxifloxacin-13C-d3 是 Moxifloxacin 的 13C 和氘代化合物。Moxifloxacin 的 CAS 号为 151096-09-2。Moxifloxacin 是一种8-甲氧基喹诺酮类口服有效抗菌药物，用于急性细菌性鼻窦炎，慢性支气管炎的急性细菌性加重和感染性肺炎的研究。
TMID-0184	Antipyrine-d3
	Antipyrine-d3 是 Antipyrine 的氘代化合物。Antipyrine 的 CAS 号为 60-80-0。Antipyrine 是一种退烧剂和止痛剂。它可用作氧化药物代谢的探针药物，常用于评估人类的肝氧化能力。
TMID-0082	Lopinavir-d8
	Lopinavir-d8 是 Lopinavir 的氘代化合物。Lopinavir 的 CAS 号为 192725-17-0。Lopinavir 是一种选择性肽模拟 HIV-1 蛋白酶的高效抑制剂。它通过阻止 HIV-1 的成熟而起作用，从而阻断其感染性。它也是SARS-CoV 3CLpro的抑制剂。
TMIJ-0215	Doxofylline-d4
	Doxofylline-d4 是 Doxofylline 的氘代化合物。Doxofylline 的 CAS 号为 69975-86-6。Doxofylline 是腺苷 A1 受体拮抗剂，且能抑制磷酸二酯酶 IV，用于治疗哮喘。
TMID-0118	Doxofylline-d6
	Doxofylline-d6 是 Doxofylline 的氘代化合物。Doxofylline 的 CAS 号为 69975-86-6。Doxofylline 是腺苷 A1 受体拮抗剂，且能抑制磷酸二酯酶 IV，用于治疗哮喘。
TMIJ-0305	10,11-Dihydro-10-hydroxy Carbamazepine-d4
	10,11-Dihydro-10-hydroxy Carbamazepine-d4 是 10,11-Dihydro-10-hydroxy Carbamazepine 的氘代化合物。10,11-Dihydro-10-hydroxy Carbamazepine 的 CAS 号为 29331-92-8。Licarbazepine 是一种有效的电压门控钠通道阻滞剂，具有抗惊厥和稳定情绪的功效。
TMIJ-0103	Suplatast Tosylate-d5
	Suplatast Tosylate-d5 是 Suplatast Tosylate 的氘代化合物。Suplatast Tosylate 的 CAS 号为 94055-76-2。Suplatast Tosilate 是一种口服有活性的 Th2 细胞因子抑制剂，能够阻碍 Th2 细胞产生 IL-4 和 IL-5 ，并对 IgE 的合成具有抑制作用。它是一种抗过敏剂，它具有抗纤维化、抗哮喘及抗炎特性。
T71288	Phenylbutazone-d9
	Phenylbutazone-d9 is intended for use as an internal standard for the quantification of phenylbutazone by GC- or LC-MS. Phenylbutazone is a non-steroidal anti-inflammatory drug and an inhibitor of the peroxidase activity of COX (IC50 = ~100 µM in the presence of hydrogen peroxide). It also inhibits prostaglandin I synthase (IC50 = ~25 µM in the presence of hydrogen peroxide). Phenylbutazone (2 mg/kg) reduces increases in type II collagen levels in the inflamed joints of an equine model of LPS-in...
TMIH-0181	Demethoxy Curcumin-d4
	Demethoxy Curcumin-d4 是 Demethoxy Curcumin 的氘代化合物。Demethoxy Curcumin 的 CAS 号为 22608-11-3。Demethoxycurcumin是姜黄素的主要活性成分，有抗炎和抗癌作用。
TMID-0053	Amisulpride-d5
	Amisulpride-d5 是 Amisulpride 的氘代化合物。Amisulpride 的 CAS 号为 71675-85-9。Amisulpride 是多巴胺D2/D3受体拮抗剂，对于人多巴胺D2和D3的Ki分别为 2.8 和 3.2 nM。
TMID-0208	Hydroxychloroquine-d5
	Hydroxychloroquine-d5 是 Hydroxychloroquine 的氘代化合物。Hydroxychloroquine 的 CAS 号为 118-42-3。Hydroxychloroquine 是一种合成抗疟疾剂，有效抑制SARS-CoV-2感染，也抑制 Toll 样受体 7/9 信号传导。
TMID-0292	Tylosin-d3
	Tylosin-d3 是 Tylosin 的氘代化合物。Tylosin 的 CAS 号为 1401-69-0。Tylosin 是一种兽医用大环内酯类抗生素，是Streptomyces fradiae的产物。它对革兰氏阳性菌具有高抗菌活性。它是饲料添加剂用于促进动物生长。它被用于治疗家禽、猪和牛的细菌性痢疾和呼吸道疾病。
TMIJ-0139	Ticagrelor-d7
	Ticagrelor-d7 是 Ticagrelor 的氘代化合物。Ticagrelor 的 CAS 号为 274693-27-5。Ticagrelor (AZD6140) 是可逆的，可口服的P2Y12受体拮抗剂，可抑制血小板聚集。
T35915	Erlotinib-13C6 Erlotinib-13C6
	Erlotinib-13C6 (CP-358774-13C6) is a 13C-labeled Erlotinib. Erlotinib is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR[1]. Erlotinib reduces EGFR autophosphorylation in intact tumor cells with an IC50 of 20 nM. Erlotinib is used for the treatment of non-small cell lung cancer[1].Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process[2]...
TMIJ-0274	Sulindac-d3
	Sulindac-d3 是 Sulindac 的氘代化合物。Sulindac 的 CAS 号为 38194-50-2。Sulindac 是一种非甾体类抗炎剂，可抑制COX-2的活性，也可抑制 COX-2 的过表达。它是一种亚磺酰基茚衍生物前药，具有潜在的抗肿瘤活性。
TMID-0070	Amiodarone-d10 Hydrochloride
	Amiodarone-d10 Hydrochloride 是 Amiodarone Hydrochloride 的氘代化合物。Amiodarone Hydrochloride 的 CAS 号为 19774-82-4。Amiodarone hydrochloride是一种抗心绞痛和 III 类抗心律失常药物，通过抑制钾通道和电压门控钠通道来增加心室和心房肌肉作用的持续时间，可导致心率和血管阻力降低。它通过成纤维细胞中的ERK1/2和p38 MAPK信号传导诱导细胞增殖和肌成纤维细胞分化，可研究室上性和室性心律失常。
TMID-0069	Amiodarone-d4 HCl
	Amiodarone-d4 HCl 是 Amiodarone HCl 的氘代化合物。Amiodarone HCl 的 CAS 号为 19774-82-4。Amiodarone hydrochloride是一种抗心绞痛和 III 类抗心律失常药物，通过抑制钾通道和电压门控钠通道来增加心室和心房肌肉作用的持续时间，可导致心率和血管阻力降低。它通过成纤维细胞中的ERK1/2和p38 MAPK信号传导诱导细胞增殖和肌成纤维细胞分化，可研究室上性和室性心律失常。
T71212	Lornoxicam-d4
	Lornoxicam-d4 is intended for use as an internal standard for the quantification of lornoxicam by GC- or LC-MS. Lornoxicam is a COX inhibitor and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory and analgesic properties. It inhibits production of thromboxane B2 from arachidonic acid in HEL human erythroleukemic cells, which endogenously express COX-1, as well as inhibits LPS-induced formation of prostaglandin F1α from arachidonic acid in Mono-Mac-6 cells, which endogenously e...
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同位素标记化合物

Perphenazine D8 Dihydrochloride

Cat.No: T12411

Target: Others

Lumefantrine-d18

Cat.No: T11891

Synonym: Benflumetol D18,苯芴醇 D18,Lumefantrine D18

Target: Others

Dimetridazole-d3

Cat.No: TMIJ-0449

L-Aspartic acid 13C

Cat.No: T40915

Cat.No: T31108

Synonym: CTP347,CTP 347

Cat.No: T12336

Synonym: Wy-21743 D4

Target: Others

Tiaprofenic acid D3

Cat.No: T13155

Target: Others

Cat.No: T19183

Synonym: Albendazole D3

Target: Others

(S)-Ketoprofen-d3

Cat.No: TMIJ-0207

Sarafloxacin-d8 Hydrochloride

Cat.No: TMIJ-0037

Cat.No: TMIH-0496

Cat.No: TMIH-0494

Flunixin-d3 (methyl-d3)

Cat.No: TMIJ-0298

Norfluoxetine-d5 Hydrochloride

Cat.No: TMID-0217

Hydroxy Ipronidazole-d3

Cat.No: TMIJ-0394

Rifampicin-13C-d3

Cat.No: TMID-0199

4-Trifluoromethylsalicylic acid-13C6

Cat.No: T38638

Synonym: 4-Trifluoromethylsalicylic acid-13C6,Desacetyl triflusal-13C6

Butylphthalide-d7

Cat.No: TMIH-0130

Synonym: NBP-d7

Buspirone EP Impurity A-d8

Cat.No: TMIJ-0096

Synonym: Buspirone USP Related Compound A-d8

Cat.No: TMID-0015

3-Butylphthalide-d9

Cat.No: TMIJ-0105

Cat.No: TMID-0198

Olmesartan-d6 Acid

Cat.No: TMID-0241

Cat.No: TMIJ-0102

Moxifloxacin-d4

Cat.No: TMIJ-0059

Cat.No: TMID-0276

Ketorolac-d5-P1

Cat.No: TMIH-0290

Ketorolac-d5-P2

Cat.No: TMIH-0291

10,11-Dihydro-10-hydroxycarbamazepine-d4

Cat.No: TMIH-0024

Synonym: rac-Licarbazepine-d4

N-Carbobenzyloxyglycine-d2

Cat.No: TMIJ-0079

Dehydro aripiprazole-d8

Cat.No: TMIJ-0335

(±)-Ropivacaine-d7

Cat.No: TMID-0185

Moxifloxacin-13C-d3

Cat.No: TMID-0281

Cat.No: TMID-0184

Cat.No: TMID-0082

Cat.No: TMIJ-0215

Cat.No: TMID-0118

10,11-Dihydro-10-hydroxy Carbamazepine-d4

Cat.No: TMIJ-0305

Suplatast Tosylate-d5

Cat.No: TMIJ-0103

Phenylbutazone-d9

Cat.No: T71288

Demethoxy Curcumin-d4

Cat.No: TMIH-0181

Cat.No: TMID-0053

Hydroxychloroquine-d5

Cat.No: TMID-0208

Cat.No: TMID-0292

Cat.No: TMIJ-0139

Cat.No: T35915

Synonym: Erlotinib-13C6

Cat.No: TMIJ-0274

Amiodarone-d10 Hydrochloride

Cat.No: TMID-0070

Amiodarone-d4 HCl

Cat.No: TMID-0069

Cat.No: T71212

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