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HSD17B13-IN-33 (Compound 115) 是一种抑制hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) 的化合物,其IC50值对雌二醇小于0.1 μM。此化合物主要用于研究肝病、代谢性疾病或心血管疾病,例如非酒精性脂肪肝病(NAFLD)、非酒精性脂肪性肝炎(NASH)或药物性肝损伤(DILI)。
HSD17B13-IN-33 (Compound 115) 是一种抑制hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) 的化合物,其IC50值对雌二醇小于0.1 μM。此化合物主要用于研究肝病、代谢性疾病或心血管疾病,例如非酒精性脂肪肝病(NAFLD)、非酒精性脂肪性肝炎(NASH)或药物性肝损伤(DILI)。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 10-14周 | |
50 mg | 询价 | 10-14周 |
产品描述 | HSD17B13-IN-33 (Compound 115), a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibits an IC 50 of less than 0.1 μM for estradiol. This compound is applicable in the research of liver diseases, metabolic disorders, and cardiovascular conditions including NAFLD, NASH, and drug-induced liver injury (DILI) [1]. |
分子量 | 385.36 |
分子式 | C20H17F2N3O3 |
CAS No. | 2730027-85-5 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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