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Lorvotuzumab (Anti-NCAM1/CD56 Reference Antibody (lorvotuzumab)) 是一种人源化结合 CD56 (NCAM1) 的单克隆抗体。Lorvotuzumab 可用于合成抗体-药物偶联物( Lorvotuzumab mertansine)。
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Lorvotuzumab (Anti-NCAM1/CD56 Reference Antibody (lorvotuzumab)) 是一种人源化结合 CD56 (NCAM1) 的单克隆抗体。Lorvotuzumab 可用于合成抗体-药物偶联物( Lorvotuzumab mertansine)。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 2,480 | 现货 | |
5 mg | ¥ 6,220 | 现货 | |
10 mg | ¥ 8,380 | 现货 | |
25 mg | ¥ 12,300 | 现货 | |
50 mg | ¥ 16,700 | 现货 |
产品描述 | Lorvotuzumab (Anti-NCAM1/CD56 Reference Antibody (lorvotuzumab)) is a humanized monoclonal antibody that binds to CD56 (NCAM1). Lorvotuzumab can be used to synthesize antibody-drug conjugate (Lorvotuzumab mertansine). |
体外活性 | Lorvotuzumab mertansine (IMGN901) 是一种抗体-药物偶联物(ADC),它通过二硫键将强效的抗有丝分裂剂DM1与针对CD56的抗体(Lorvotuzumab)连接起来。Lorvotuzumab mertansine 对Wilms'肿瘤、横纹肌肉瘤和神经母细胞瘤有有效作用。 |
体内活性 | Lorvotuzumab mertansine (IMGN901) is an antibody-drug conjugate (ADC) that utilizes a disulfide linker to connect the potent anti-mitotic agent DM1 to the CD56-targeting antibody (Lorvotuzumab). Lorvotuzumab mertansine is effective against Wilms' tumor, rhabdomyosarcoma, and neuroblastoma. |
别名 | 洛沃妥珠单抗 |
分子量 | 146.44 kDa |
CAS No. | 339306-30-8 |
存储 | store at low temperature | store at -80°C | Shipping with blue ice. |
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