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Nemorubicin (PNU 152243) 是一种 Doxorubicin 衍生物,具有抗肿瘤活性。它需要完整的核苷酸切除修复系统才能发挥活性。它对多药耐药表型的多种肿瘤细胞系具有细胞毒性。
Nemorubicin (PNU 152243) 是一种 Doxorubicin 衍生物,具有抗肿瘤活性。它需要完整的核苷酸切除修复系统才能发挥活性。它对多药耐药表型的多种肿瘤细胞系具有细胞毒性。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 488 | 现货 | |
2 mg | ¥ 715 | 现货 | |
5 mg | ¥ 1,180 | 现货 | |
10 mg | ¥ 1,920 | 现货 | |
25 mg | ¥ 3,280 | 现货 | |
50 mg | ¥ 4,850 | 现货 | |
100 mg | ¥ 6,730 | 现货 |
产品描述 | Nemorubicin (PNU 152243) is a doxorubicin derivative that differs significantly from its parent drug in terms of spectrum of antitumor activity, metabolism and toxicity profile. The drug is active on tumors resistant to alkylating agents, topoisomerase II inhibitors and platinum derivatives. |
别名 | 奈莫柔比星, PNU-152243A, PNU 152243, Methoxymorpholinyldoxorubicin |
分子量 | 643.64 |
分子式 | C32H37NO13 |
CAS No. | 108852-90-0 |
Smiles | [H][C@@]1(C[C@@](O)(Cc2c(O)c3C(=O)c4cccc(OC)c4C(=O)c3c(O)c12)C(=O)CO)O[C@H]1C[C@@H]([C@H](O)[C@H](C)O1)N1CCO[C@@H](C1)OC |
密度 | 1.55 g/cm3 (Predicted) |
存储 | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 45 mg/mL (69.91 mM) | ||||||||||||||||||||||||||||||
溶液配制表 | |||||||||||||||||||||||||||||||
DMSO
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