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Val-Ala-PAB 是 Tesirine (a.k.a. SG3249) 合成的基石,Tesirine 是一种临床抗体-药物偶联物吡咯并苯二氮卓二聚体有效载荷。制备吡咯并苯二氮卓二聚体及其抗体缀合物的试剂,该试剂含有可用于治疗包括癌症在内的增殖性疾病的肽接头。
Val-Ala-PAB 是 Tesirine (a.k.a. SG3249) 合成的基石,Tesirine 是一种临床抗体-药物偶联物吡咯并苯二氮卓二聚体有效载荷。制备吡咯并苯二氮卓二聚体及其抗体缀合物的试剂,该试剂含有可用于治疗包括癌症在内的增殖性疾病的肽接头。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | ¥ 119 | 现货 |
产品描述 | Val-Ala-PAB is a building block in the synthesis of Tesirine (a.k.a. SG3249), a clinical antibody-drug conjugate pyrrolobenzodiazepine dimer payload. Reagent in the preparation of pyrrolobenzodiazepine dimers and their antibody conjugates containing peptide linkers useful for treating proliferative including cancer. |
分子量 | 293.36 |
分子式 | C15H23N3O3 |
CAS No. | 1343476-44-7 |
Smiles | CC(C)[C@H](N)C(=O)N[C@@H](C)C(=O)Nc1ccc(CO)cc1 |
密度 | 1.191 g/cm3 (Predicted) |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 50 mg/mL (170.43 mM) | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
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