KY-556

Name: KY-556
Brand: TargetMol
SKU: T15676
Rating: 4.5 (1 reviews)

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产品编号 T15676Cas号 110816-78-9

别名 N556

KY-556 is a promising and orally-active pro-drug of disodium cromoglycate (DSCG). It also against allergic diseases.

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产品编号 T15676 别名 N556Cas号 110816-78-9

KY-556 is a promising and orally-active pro-drug of disodium cromoglycate (DSCG). It also against allergic diseases.

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生物活性

产品描述	KY-556 is a promising and orally-active pro-drug of disodium cromoglycate (DSCG). It also against allergic diseases.
体内活性	N-556 (100 mg/kg, p.o.) displays the prolongation of survival time in the rat systemic anaphylaxis. N-556 (100 mg/kg, p.o.) significantly inhibits the increased airway resistance in experimental asthma in rats. N-556 (10-100 mg/kg, p.o.) inhibits dose-dependently the 48-hr homologous passive cutaneous anaphylaxis (PCA) in rats, and the duration of action is longer than that of intravenous Disodium cromoglycate (DSCG). The oral anti-allergic effect of KY-556 is investigated. N-556 (20 and 100 mg/kg once a day for 20 consecutive days, p.o.) tends to inhibit the histamine release from actively sensitized rat lung fragments [1].
别名	N556