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Phenyl-glutarimide 4'-piperazine是一种具有piperazine功能化的cereblon配体,可用于PROTACDegrader的开发。该化合物可用于开发PG-PROTACs,与使用IMiD(immunomodulatory imide drug)类似物合成的PROTACs相比,展示出改善的水解稳定性和效力。
Phenyl-glutarimide 4'-piperazine是一种具有piperazine功能化的cereblon配体,可用于PROTACDegrader的开发。该化合物可用于开发PG-PROTACs,与使用IMiD(immunomodulatory imide drug)类似物合成的PROTACs相比,展示出改善的水解稳定性和效力。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
100 mg | ¥ 6,450 | 35日内发货 |
产品描述 | Phenyl-glutarimide 4'-piperazine, a piperazine-functionalized cereblon ligand, facilitates the development of PG-PROTACs with enhanced hydrolytic stability and potency compared to those produced with IMiD (immunomodulatory imide drug) analogs. It serves as a foundation for PROTACDegrader development. |
分子量 | 346.25 |
分子式 | C15H19N3O2.2HCl |
CAS No. | 2902651-89-0 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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