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Antibacterialagent 227 (Compd 29) 作为一种ThrRS(Seryl-tRNA synthetase,丝氨酰-tRNA 合成酶)抑制剂,对浮游及生物膜状态的金黄色葡萄球菌 (Staphylococcus aureus 25923) 显示出显著的抑制效果,其最低抑菌浓度 (MIC) 达到 32 µg/ml.这表明Antibacterialagent 227 可能是对抗多药耐药的金黄色葡萄球菌生物膜形成的有效防腐剂.
Antibacterialagent 227 (Compd 29) 作为一种ThrRS(Seryl-tRNA synthetase,丝氨酰-tRNA 合成酶)抑制剂,对浮游及生物膜状态的金黄色葡萄球菌 (Staphylococcus aureus 25923) 显示出显著的抑制效果,其最低抑菌浓度 (MIC) 达到 32 µg/ml.这表明Antibacterialagent 227 可能是对抗多药耐药的金黄色葡萄球菌生物膜形成的有效防腐剂.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 10-14周 | |
50 mg | 询价 | 10-14周 |
产品描述 | Antibacterialagent 227 (Compd 29) acts as an inhibitor for ThrRS (Seryl-tRNA synthetase), efficiently suppressing the growth of both planktonic and biofilm-cultured Staphylococcus aureus (Staphylococcus aureus 25923). The minimum inhibitory concentration (MIC) for this compound is identified at 32 µg/ml. Due to its efficacy, Antibacterialagent 227 is a promising preservative against multi-drug resistant biofilms formed by Staphylococcus aureus strains. |
体外活性 | 抗菌剂227(0-32 µg/ml)对S. aureus 25923的浮游培养物展现出明显的抑制效能,然而对革兰氏阴性菌E. coli的抗菌活性未见明显. |
分子量 | 275.26 |
分子式 | C12H13N5O3 |
CAS No. | 301304-67-6 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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