Bisantrene (CL-216942; NSC 337766) is a topoisomerase II poison and DNA intercalator. It can be used as a Rac1 inhibitor or model compound to study P-glycoprotein-mediated multi-drug resistance (MDR1). Bisantrene inserts and disrupts the configuration of DNA, leading to DNA single-strand breaks, DNA-protein cross-links, and DNA replication inhibition.
Bisantrene (CL-216942; NSC 337766) is a topoisomerase II poison and DNA intercalator. It can be used as a Rac1 inhibitor or model compound to study P-glycoprotein-mediated multi-drug resistance (MDR1). Bisantrene inserts and disrupts the configuration of DNA, leading to DNA single-strand breaks, DNA-protein cross-links, and DNA replication inhibition.
Bisantrene (CL-216942; NSC 337766) is a topoisomerase II poison and DNA intercalator. It can be used as a Rac1 inhibitor or model compound to study P-glycoprotein-mediated multi-drug resistance (MDR1). Bisantrene inserts and disrupts the configuration of DNA, leading to DNA single-strand breaks, DNA-protein cross-links, and DNA replication inhibition.
别名
NSC-337766, CL-216942, CL216942, CL 216942
化学信息
分子量
434.93
分子式
C22H23ClN8
CAS No.
71439-68-4
密度
no data available
储存&溶解度
存储
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
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