Chitin Synthase Inhibitor 10, as a potent chitin synthase inhibitor, exhibits remarkable inhibitory activity with an IC50 of 0.11 mM. It also functions as an antifungal agent, demonstrating substantial effectiveness against drug-resistant fungi, including C. albicans and C. neoformans. The compound is useful in researching invasive fungal infections (IFIs) [1].

几丁质合成酶抑制剂10（化合物9o）（浓度为300 μg/mL）对几丁质合成酶显示出良好的抑制作用，IC50值为0.11 mM [1]。几丁质合成酶抑制剂10对C. albicans、A. flavus、A. fumigatus和C. neoformans具有抗真菌活性，其最小抑菌浓度（MIC）分别为64 μg/mL、256 μg/mL、128 μg/mL和64 μg/mL [1]。几丁质合成酶抑制剂10与细胞壁结构的破坏有关 [1]。