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Search Results for " synthesis "

Targets Recommended: DNA/RNA Synthesis Others

2965

抑制剂 & 化合物

361

天然产物

12

化合物库

2

TargetMol 试剂盒

224

重组蛋白

42

同位素标记化合物

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Cat. No.	Product Name
L7810	高溶解性多官能团片段化合物库		1159 compounds
	高溶解性多官能团片段库包含1159 种片段分子
L2510	脂代谢化合物库		492 compounds
	492 个脂代谢相关的化合物集合，可用于高通量和高内涵筛选；
L5500	毒性化合物库		262 compounds
	262 个细胞毒性化合物的特有集合，可用于高通量、高内涵筛选。
L9001	食品添加剂化合物库		425 compounds
	425种食品添加剂的集合
L2550	谷氨酰胺代谢化合物库		565 compounds
	565 种谷氨酰胺代谢相关的分子，可以用于高通量和高内涵筛选；
L8100	细胞周期化合物库		677 compounds
	677 种细胞周期相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L1120	AMPK靶向分子库		80 compounds
	80 个靶向AMPK 的分子集合，可用于高通量和高内涵筛选；
L7900	成骨分子库		317 compounds
	317 种成骨相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L9700	内质网应激化合物库		193 compounds
	193 个内质网应激相关的化合物集合，可用于高通量和高内涵筛选；
L9600	多肽分子库		791 compounds
	791 种多肽类分子，可用于多肽药物开发及信号转导通路和作用机制研究；
L6030	天然产物衍生物虚筛化合物库		163000 compounds
	16.3万种天然产物衍生物，并且在持续增加中；
L9300	大环化合物库		210 compounds
	210 种活性已知的大环化合物，用于高通量、高内涵筛选；

化合物库

高溶解性多官能团片段化合物库

Cat.No: L7810

Compounds: 1159

脂代谢化合物库

Cat.No: L2510

Compounds: 492

毒性化合物库

Cat.No: L5500

Compounds: 262

食品添加剂化合物库

Cat.No: L9001

Compounds: 425

谷氨酰胺代谢化合物库

Cat.No: L2550

Compounds: 565

细胞周期化合物库

Cat.No: L8100

Compounds: 677

AMPK靶向分子库

Cat.No: L1120

Compounds: 80

成骨分子库

Cat.No: L7900

Compounds: 317

内质网应激化合物库

Cat.No: L9700

Compounds: 193

多肽分子库

Cat.No: L9600

Compounds: 791

天然产物衍生物虚筛化合物库

Cat.No: L6030

Compounds: 163000

大环化合物库

Cat.No: L9300

Compounds: 210

Cat. No.	Product Name	Form	Specificity Of Inhibition
C0051	Penicillin-Streptomycin Solution (100×), Sterile 青霉素-链霉素双抗溶液（100×），灭菌	Solution in bottle
C0052	Penicillin-Streptomycin-Amphotericin B Solution (100×), Sterile 青霉素-链霉素-两性霉素B三抗溶液（100×），灭菌	Solution in bottle

TargetMol 试剂盒

青霉素-链霉素双抗溶液（100×），灭菌

Cat.No: C0051

青霉素-链霉素-两性霉素B三抗溶液（100×），灭菌

Cat.No: C0052

Cat. No.	Product Name	Target	Signaling Pathways
T9978	Glutathione synthesis-IN-1	Others	Others
	Glutathione synthesis-IN-1 (DC-1)是谷胱甘肽合成抑制剂。
T82944	ATP Synthesis-IN-2	Others	Others
	ATP Synthesis-IN-2 (Compound 5) 是一种有效的ATP合成活性抑制剂，对Pseudomonas aeruginosa (PA) 表现出抗菌活性，其IC50值为0.7 μg/mL。
T82945	ATP Synthesis-IN-1	Others	Others
	ATP Synthesis-IN-1（Compound 4）为喹啉衍生物，有效抑制PA ATP合成，IC50为11.1μg/mL。本化合物亦展示抗菌特性，适用于研究耐药PA感染。
T36757	DMT-dU-CE Phosphoramidite	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	DMT-dU-CE Phosphoramidite 是一个核苷分子，通常用于合成 DNA 和 DNA 测序试验。
TP1115	L-Asparaginase L-ASNase	Others	Others
	L-Asparaginase (L-ASNase) 是催化 L-天冬酰胺转化的水解酶，从血浆中去除 L-天冬酰胺，导致 RNA 和 DNA 合成抑制，随后引起细胞凋亡。它用于急性淋巴细胞白血病的研究。
T14522	Beaucage reagent	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Beaucage reagent 可用于DNA切割。
T20700	Racemetirosine	Others	Others
	Racemetirosine 是一种酪氨酸 3-单加氧酶抑制剂，因此会抑制儿茶酚胺的合成。
T15611	JH-RE-06	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	JH-RE-06是一种REV1-REV7互作抑制剂，IC50为0.78 μM，Kd 为0.42 μM。它靶向与 POLζ 的 REV7 亚基相互作用的 REV1，可改善化疗效果。它通过阻止诱变 POLζ 的募集来破坏诱变性跨损伤合成。
T8003	Methotrexate disodium	Apoptosis; Dehydrogenase; DNA/RNA Synthesis; Antifolate; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Methotrexate disodium 是一种叶酸类似物代谢抑制剂，具有免疫抑制剂和抗肿瘤特性，用于类风湿关节炎和研究多种癌症。
T12019	Methylproamine	Others	Others
	Methylproamine是一种与DNA结合的辐射保护剂，可以修复辐射诱导的短暂活性氧。
T36756	DMT-dG(ib) Phosphoramidite	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	DMT-dG(ib) Phosphoramidite 可用于 DNA 的合成。
T6801	CeMMEC13	Carboxypeptidase; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Proteases/Proteasome
	CeMMEC13 是一种异喹啉酮，可选择性抑制 TAF1 的第二个溴结构域，IC50为 2.1 μM。
T1154	Rifaximin	DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Rifaximin 是一种胃肠道选择性抗生素，与细菌 DNA 依赖性 RNA 聚合酶的 β 亚基结合，抑制细菌 RNA 合成。与革兰氏阴性菌（MIC：8-50 毫克/毫升）相比，它对革兰氏阳性菌株（MIC：0.03-5 毫克/毫升）的敏感性更高。
T3279	Silver sulfadiazine Silvadene,磺胺嘧啶银,Dermazin,Flamazine	DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Silver sulfadiazine (Dermazin) 是一种磺胺类抗生素，具有抗菌和抗真菌活性。它的通磺胺部分(SD-SDZ) 对细菌生长有双重抑制作用，可阻止细菌叶酸吸收以及 DNA 合成。它释放的银结合并破坏 DNA 结构，阻止细菌 DNA 复制。
T8886	NITD-2	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	NITD-2 是一种登革病毒 (DENV) 聚合酶抑制剂，可抑制 DENV RdRp 介导的 RNA 延伸。
T5637	Triflumuron	Others	Others
	Triflumuron 是一种杀虫剂，属于所谓的昆虫生长调节剂。它抑制昆虫幼虫合成甲壳素，导致死亡。
T2100	CX-5461	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	CX5461 是一种口服有效的rRNA 合成抑制剂，可抑制 Pol I 驱动的 rRNA 转录。
T2037	TH588	DNA/RNA Synthesis; MTH1	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	TH588 是 nudix 水解酶家族抑制剂，可有效和选择性地参与和抑制细胞中的 MTH1，IC50值 5 nM。
T14501	BAY-2402234	Dehydrogenase; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	BAY-2402234 是一种选择性二氢乳清酸脱氢酶的抑制剂，可研究骨髓恶性肿瘤。
T2410	Nedaplatin 奈达铂,NSC 375101D	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Nedaplatin (NSC-375101D) 是顺铂的衍生物，是肿瘤集落形成单位的 DNA 损伤剂，IC50为94 μM。
T8955	PCNA-I1	Others	Others
	PCNA-I1 是PCNA(增殖细胞核抗原)抑制剂。它能够直接与 PCNA 三聚体结合(Kd:0.41 μM)，在体内外均表现出抗肿瘤活性。
T1233	Oxolinic acid Emyrenil,Nidantin,NSC 110364,恶喹酸,Dioxacin,Urinox	Dopamine Receptor; DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; GPCR/G Protein; Microbiology/Virology; Neuroscience
	Oxolinic acid (Nidantin) 是一种抗生素，对革兰氏阴性菌和革兰氏阳性菌均有效，可研究急性和慢性尿路感染。它是一种 DNA/RNA 合成抑制剂，也是一种多巴胺摄取抑制剂，能刺激小鼠的活跃过度。
T36687	Ac-rC Phosphoramidite	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Ac-rC Phosphoramidite 可以修饰二硫化磷酸寡核苷酸。
T5639	lufenuron Fluphenacur,虱螨脲	Parasite	Microbiology/Virology
	Lufenuron (Fluphenacur) 和几丁质合成抑制剂，可抑制节肢动物的蜕皮，控制蚤和鱼虱。
T40192	dGTP 2′-脱氧鸟苷 5′-(四氢三磷酸酯),2'-Deoxyguanosine-5'-triphosphate	Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	dGTP（2'-Deoxyguanosine-5'-triphosphate）作为脱氧核糖核酸（DNA）合成的基本单元，属于鸟苷核苷酸，对8-O-GDP、8-O-dGTP、8-O-GTP及8-O-dGTP的氧化损伤具有高度敏感性。
T15235	Enocitabine	Nucleoside Antimetabolite/Analog; HCV Protease; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
	Enocitabine 是一种核苷类似物，抑制 DNA 复制剂。Enocitabine 抑制人巨细胞病毒的复制，显示出抗白血病和抗病毒活性。
T40168	DHODH-IN-16	Dehydrogenase	Metabolism
	DHODH-IN-16 是一种有效的二氢乳清酸脱氢酶抑制剂（DHODH，IC50 = 0.396 nM）。
T35648	4-Thiouridine	Others	Others
	4-Thiouridine (4-TU) 是一种光活化核糖核苷类似物，广泛用于RNA 分析。
T8873	Bractoppin	Others; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others
	Bractoppin 是一种BRCA1 (t)BRCT domain 识别磷酸肽的选择性抑制剂，IC50为 74 nM。它优先抑制 BRCA1 -tBRCT 依赖的 DNA 损伤。它减少 BRCA1 对 DNA 断裂片段的招募，进而抑制损伤诱导的 G2 期阻滞和重组酶 RAD51 的组装。
T12438	PfDHODH-IN-1	Dehydrogenase; Parasite	Metabolism; Microbiology/Virology
	PfDHODH-IN-1 是 Leflunomide 活性代谢物的类似物，具有抗疟疾活性。它是恶性疟原虫二氢乳清酸脱氢酶抑制剂。
T1349	5-Fluorouridine	Others; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others
	5-Fluorouridine 是一种 5-fluorouracil 的代谢物，具有抗癌作用。它对 L1210 细胞的生长具有细胞毒性作用，其作用的 IC50值为 2 nM。它能抑制人结肠癌细胞 rRNA 的合成。
T7747	Datelliptium chloride hydrochloride	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Datelliptium chloride hydrochloride 是一种衍生自玫瑰树碱的 DNA 嵌入剂，具有抗肿瘤活性。
T10411	AU1235	Antibacterial	Microbiology/Virology
	AU1235是金刚烷脲，是一种MmpL3抑制剂。结核分枝杆菌蛋白MmpL3在细胞壁合成中起重要作用，它影响海藻糖单支霉菌酸酯跨内膜转运。
T11020	DHODH-IN-11	Dehydrogenase; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	DHODH-IN-11 是一种来氟米特衍生物和弱二氢乳清酸脱氢酶 (DHODH) 抑制剂，pKa 为 5.03
T40661	ML-60218	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	ML-60218 是广谱 RNA pol III 抑制剂，对酿酒酵母和人类的 IC50 分别为 32 和 27 μM。 ML-60218 会破坏已组装的病毒质并阻碍新病毒质的形成。
T38237	2′-O-Methylcytidine	Nucleoside Antimetabolite/Analog; HCV Protease	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
	2'-O-Methylcytidine 是 2'-代核苷，可抑制 HCV 复制。它在体外抑制 NS5B 催化的 RNA 合成，其抑制方式是与底物核苷三磷酸竞争。
T16703	Quarfloxin CX-3543	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Quarfloxin (CX-3543) 是一种氟喹诺酮衍生物，具有抗肿瘤活性，可靶向抑制RNA pol I 的活性，在神经母细胞瘤细胞中的 IC50 值在纳摩尔范围内。它破坏核糖体 DNA 模板中核仁蛋白和 G-四链体 DNA 结构之间的相互作用。
T2069L	TH287 hydrochloride	DNA/RNA Synthesis; MTH1	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	TH287 hydrochloride 是一种选择性MTH1抑制剂，IC50值为 0.8 nM。它可用于治疗癌症的研究。
T13659	DMTr-LNA-5MeU-3-CED-phosphoramidite	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	DMTr-LNA-5MeU-3-CED-phosphoramidite 是核苷的衍生物。
T9103	BVDV-IN-1	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	BVDV-IN-1 是一种牛病毒性腹泻病毒 (BVDV) 的非核苷抑制剂 (NNI)，EC50 为 1.8 μM。它直接与 BVDV RdRp 的疏水口袋结合，对耐 NNI 氨基硫脲 (TSC) 的 BVDV 具有抗病毒活性。
T8747	Levofloxacin hydrochloride	DNA gyrase; Topoisomerase	DNA Damage/DNA Repair
	Levofloxacin hydrochloride 是一种广谱的第三代氟喹诺酮类抗生素，是氧氟沙星的光学活性 L-异构体，具有抗菌活性。左氧氟沙星通过细菌细胞壁扩散并通过抑制 DNA 促旋酶（细菌拓扑异构酶 II）起作用，这是一种 DNA 复制、RNA 转录和细菌 DNA 修复所需的酶。 DNA 促旋酶活性的抑制导致细菌细胞生长受阻。
T9121	AG-636	Dehydrogenase; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	AG-636 是一种选择性可逆和具有口服活性的二氢乳清酸脱氢酶(DHODH)抑制剂，IC50 为 17 nM，具有很强的抗癌作用。
T10384	Farudodstat ASLAN003	Apoptosis; Dehydrogenase; DNA/RNA Synthesis	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Farudodstat (ASLAN003) 是一种具有口服活性的二氢乳清酸脱氢酶 (DHODH) 抑制剂，对人 DHODH 酶的IC50为 35 nM。它通过激活 AP-1 转录因子来抑制蛋白质合成，可以诱导凋亡，并在急性髓样白血病异种移植小鼠中大大延长其生存期。
T4345	CeMMEC1 CeMMEC1 HCl	Epigenetic Reader Domain; Carboxypeptidase; DNA/RNA Synthesis	Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair; Proteases/Proteasome
	CeMMEC1 是一种 BRD4 抑制剂，对 TAF1 有很好的亲和力，IC50为0.9 μM。
T39785L	TH5427	NUDIX hydrolase	Metabolism
	TH5427 在 NUDT5 活性和 ADP-核糖代谢中有研究的价值。它阻断孕激素依赖性、PAR 衍生的核 ATP 合成以及随后的乳腺癌细胞染色质重塑、基因调控和增殖。NUDT5是乳腺癌细胞激素依赖性基因调控和增殖的变阻器。
T8354	Triazavirin	Nucleoside Antimetabolite/Analog; Influenza Virus; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Triazavirin 是一种核酸的核苷类似物和抗病毒剂，通过抑制病毒 RNA 和 DNA 的合成以及基因组片段的复制而起作用。在流感传播阶段，它可作为保护剂。
T6357	(S)-crizotinib ent-crizotinib	Apoptosis; DNA/RNA Synthesis; MTH1	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	(S)-crizotinib (ent-crizotinib) 是一种选择性MTH1(mutT 同源物)抑制剂，IC50为 330 nM。它通过抑制 MTH1 破坏核苷酸库的稳态，诱导 DNA 单链断裂的增加，激活人结肠癌细胞的 DNA 修复，在动物模型中抑制肿瘤生长。
T7518	Deoxycytidine triphosphate trisodium salt 2'-脱氧胞苷-5'-三磷酸三钠盐,2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI	Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis; Endogenous Metabolite; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Deoxycytidine triphosphate trisodium salt (2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI) 是可用于 DNA 合成的核苷三磷酸，可用于实时荧光定量 PCR、cDNA 合成和 DNA 测序。
T1767	BMH-21 BMH21	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	BMH-21 是一种小分子 DNA 嵌入剂，可结合核糖体 DNA 并抑制 RNA 聚合酶 I (Pol I) 转录，具有抗癌活性。
T1846	Y-320 Y320	IL Receptor; Lipase; Interleukin	Immunology/Inflammation; Metabolism
	Y-320 是一种免疫调节剂，能阻碍IL-15刺激CD4 T 细胞后的IL-17的产生，IC50=20~60 nM。

化合物

Glutathione synthesis-IN-1

Cat.No: T9978

Target: Others

ATP Synthesis-IN-2

Cat.No: T82944

Target: Others

ATP Synthesis-IN-1

Cat.No: T82945

Target: Others

DMT-dU-CE Phosphoramidite

Cat.No: T36757

Target: DNA/RNA Synthesis

Cat.No: TP1115

Synonym: L-ASNase

Target: Others

Beaucage reagent

Cat.No: T14522

Target: DNA/RNA Synthesis

Cat.No: T20700

Target: Others

Cat.No: T15611

Target: DNA/RNA Synthesis

Methotrexate disodium

Cat.No: T8003

Target: Apoptosis, Dehydrogenase, DNA/RNA Synthesis, Antifolate, ADC Cytotoxin

Cat.No: T12019

Target: Others

DMT-dG(ib) Phosphoramidite

Cat.No: T36756

Target: DNA/RNA Synthesis

Cat.No: T6801

Target: Carboxypeptidase, DNA/RNA Synthesis

Cat.No: T1154

Target: DNA/RNA Synthesis, Antibacterial, Antibiotic

Silver sulfadiazine

Cat.No: T3279

Synonym: Silvadene,磺胺嘧啶银,Dermazin,Flamazine

Target: DNA/RNA Synthesis, Antibacterial, Antibiotic

Cat.No: T8886

Target: DNA/RNA Synthesis

Cat.No: T5637

Target: Others

Cat.No: T2100

Target: DNA/RNA Synthesis

Cat.No: T2037

Target: DNA/RNA Synthesis, MTH1

Cat.No: T14501

Target: Dehydrogenase, DNA/RNA Synthesis

Cat.No: T2410

Synonym: 奈达铂,NSC 375101D

Target: DNA/RNA Synthesis

Cat.No: T8955

Target: Others

Cat.No: T1233

Synonym: Emyrenil,Nidantin,NSC 110364,恶喹酸,Dioxacin,Urinox

Target: Dopamine Receptor, DNA/RNA Synthesis, Antibacterial, Antibiotic

Ac-rC Phosphoramidite

Cat.No: T36687

Target: Nucleoside Antimetabolite/Analog

Cat.No: T5639

Synonym: Fluphenacur,虱螨脲

Target: Parasite

Cat.No: T40192

Synonym: 2′-脱氧鸟苷 5′-(四氢三磷酸酯),2'-Deoxyguanosine-5'-triphosphate

Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

Cat.No: T15235

Target: Nucleoside Antimetabolite/Analog, HCV Protease, DNA/RNA Synthesis

Cat.No: T40168

Target: Dehydrogenase

Cat.No: T35648

Target: Others

Cat.No: T8873

Target: Others, DNA/RNA Synthesis

Cat.No: T12438

Target: Dehydrogenase, Parasite

5-Fluorouridine

Cat.No: T1349

Target: Others, DNA/RNA Synthesis

Datelliptium chloride hydrochloride

Cat.No: T7747

Target: DNA/RNA Synthesis

Cat.No: T10411

Target: Antibacterial

Cat.No: T11020

Target: Dehydrogenase, DNA/RNA Synthesis

Cat.No: T40661

Target: DNA/RNA Synthesis

2′-O-Methylcytidine

Cat.No: T38237

Target: Nucleoside Antimetabolite/Analog, HCV Protease

Cat.No: T16703

Synonym: CX-3543

Target: DNA/RNA Synthesis

TH287 hydrochloride

Cat.No: T2069L

Target: DNA/RNA Synthesis, MTH1

DMTr-LNA-5MeU-3-CED-phosphoramidite

Cat.No: T13659

Target: Nucleoside Antimetabolite/Analog

Cat.No: T9103

Target: DNA/RNA Synthesis

Levofloxacin hydrochloride

Cat.No: T8747

Target: DNA gyrase, Topoisomerase

Cat.No: T9121

Target: Dehydrogenase, DNA/RNA Synthesis

Cat.No: T10384

Synonym: ASLAN003

Target: Apoptosis, Dehydrogenase, DNA/RNA Synthesis

Cat.No: T4345

Synonym: CeMMEC1 HCl

Target: Epigenetic Reader Domain, Carboxypeptidase, DNA/RNA Synthesis

Cat.No: T39785L

Target: NUDIX hydrolase

Cat.No: T8354

Target: Nucleoside Antimetabolite/Analog, Influenza Virus, DNA/RNA Synthesis

Cat.No: T6357

Synonym: ent-crizotinib

Target: Apoptosis, DNA/RNA Synthesis, MTH1

Deoxycytidine triphosphate trisodium salt

Cat.No: T7518

Synonym: 2'-脱氧胞苷-5'-三磷酸三钠盐,2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI

Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Endogenous Metabolite, Antibiotic

Cat.No: T1767

Synonym: BMH21

Target: DNA/RNA Synthesis

Cat.No: T1846

Synonym: Y320

Target: IL Receptor, Lipase, Interleukin

Cat. No.	Product Name	Target	Signaling Pathways
T7520	Deoxycytidine triphosphate	Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Deoxycytidine triphosphate 是一种核苷三磷酸，是合成 DNA 的原料，可用于实时荧光定量 PCR、cDNA 合成和 DNA 测序。
T13969	Xanthopterin (hydrate)	Others; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others
	Xanthopterin hydrate 是东方大黄蜂翅膀中黄色颗粒的主要成分，是一种非共轭的蝶啶天然产物，在 386/456 nm 处产生特征性的激发光。它可抑制 RNA 合成，引起大鼠肾脏生长和肥大。
T40179	Sodium Camptothecin	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Sodium Camptothecin 是一种植物生物碱，具有抗肿瘤活性。它是可逆 RNA 合成抑制剂，可以抑制腺病毒的复制。它能抑制 DNA 合成，并引起细胞内预形成的病毒 DNA 断裂。
T5270	5-Methylcytosine	Others; DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others
	5-Methylcytosine 是一种存在于真核 DNA 中的甲基化核苷酸碱基。它是由 DNA 甲基转移酶作用形成的表观遗传修饰。
T2S1635	3-Isomangostin	MTH1	DNA Damage/DNA Repair
	3-Isomangostin 可从莽吉柿壳中提取的一种天然产物，是一种乙酰胆碱酯酶选择性抑制剂，也是一种有效的人醛糖还原酶抑制剂，IC50 为 3.48 uM。它抑制 MutT 同源物 1 (MTH1)，IC50 为 52 nM。它具有清除自由基、抗疟原虫和抗癌的活性。
TN1134	Euscaphic acid	Apoptosis; LDL; PI3K; DNA/RNA Synthesis; NO Synthase; Prostaglandin Receptor	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; GPCR/G Protein; Immunology/Inflammation; Metabolism; PI3K/Akt/mTOR signaling
	Euscaphic acid 是来源于枣的一种三萜，是DNA 聚合酶抑制剂，可诱导细胞凋亡。它抑制小牛 DNA 聚合酶 α 和大鼠 DNA 聚合酶 β 的IC50值分别为 61 和 108 μM。
T5901	3-Hydroxy-2-methylpyridine	Others	Others
	3-Hydroxy-2-methylpyridine 是分离自可可碱提取物，可用于合成嘧啶。
T21498	Phleomycin	DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Phleomycin 是在链霉菌中发现的，引起 DNA 切割的抗癌糖肽抗生素之一。它类似于博来霉素，它结合并插入 DNA 以破坏双螺旋的完整性。
T1068	Dithranol 1,8,9-trihydroxyanthracene,cignoline,蒽林,Anthralin	Others; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others
	Dithranol (cignoline) 是蒽醌衍生物，可破坏线粒体功能和结构，用于治疗皮肤病。
T37101	1-Hydroxyanthraquinone	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	1-Hydroxyanthraquinone 是口服有效的天然产物，来源于植物 Tabebuia avellanedae，显示出致癌活性。
T7529	Yamogenin 山药	Others	Others
	Yamogenin 是一种薯蓣皂素的非对映异构体。它通过抑制 HepG2 肝细胞中脂肪酸合成的基因表达来抑制甘油三酸酯 (TG) 的积累。它在萤光素酶配体测定中拮抗肝脏 X 受体 (LXR) 的激活。
T7992	4-Hydroxyflavanone	NO Synthase	Immunology/Inflammation
	4-Hydroxyflavanone 是一种黄酮的合成类似物，是 SREBP 成熟和脂质合成的抑制剂。它具有研究肝脏脂肪变性及血脂异常的潜力。
T35455	N-Nitrosodiethylamine Diethylnitrosamine,NDEA	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	N-Nitrosodiethylamine (NDEA) 是致癌物质二烷基硝胺。它主要存在于水、烟草烟雾、腌制食品、油炸食品以及许多酒精饮料中。它与 DNA 修复/复制相关的核酶的变化相关。
TQ0184	Chebulinic acid	ATPase; Proton pump; DNA/RNA Synthesis; Antibacterial; TGF-beta/Smad	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Microbiology/Virology; Stem Cells
	Chebulinic acid 是从诃子果中提取的一种天然产物，结核分枝杆菌 DNA 促旋酶的有效抑制剂。它也能抑制 SMAD-3 phosphorylation 和 H+ K+-ATPase 的活性。
T13229	Tunicamycin	Influenza Virus; Antibacterial; Antibiotic; Antifungal	Microbiology/Virology
	Tunicamycin 是一种抗生素的混合物，通过阻断 GlcNAc 磷酸转移酶 (GPT)，抑制 N-连接糖基化。Tunicamycin 具有抗肿瘤活性，还具有抗细菌、抗真菌和抗病毒活性。
T6S0232	Eriodictyol 圣草酚,Huazhongilexone	Influenza Virus; DNA/RNA Synthesis; Nrf2; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Microbiology/Virology
	Eriodictyol (Huazhongilexone) 是从中草药中得到的一种黄酮类天然产物，具有抗氧化、抗炎和抗糖尿病作用。它还是一种流感依赖 RNA 的RNA 聚合酶抑制剂，IC50为 18 nM。它可诱导Nrf2信号通路。
T6S0139	Neobavaisoflavone	Apoptosis; DNA/RNA Synthesis	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Neobavaisoflavone 是一种从Psoralea corylifolia 的种子中分离出来的类黄酮。它具有抗炎，抗癌和抗氧化的作用。它在中至高浓度下可抑制 DNA 聚合酶，也可抑制血小板聚集。
T20945	2,4-D Hedonal,Macondray,2,4-D acid,Chloroxone,2,4-二氯苯氧乙酸	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	2,4-Dichlorophenoxyacetic acid (Hedonal) 是一种合成生长素，用作植物生长调节剂，也用作植物细胞培养基中的补充剂。它是除草剂中的一种活性成分，用于破坏肌动蛋白细胞骨架，以控制根系伸长和细胞生成。
T16674	Pseudouridine	Endogenous Metabolite	Metabolism
	Pseudouridine 是非编码 RNA 中丰富的修饰核苷，通过稳定 RNA 结构增强核糖体 RNA 和的转移 RNA 功能。
TN1637	Eurycomalactone	Anti-infection; NF-κB	Microbiology/Virology; NF-κB
	Eurycomalactone 是一种NF-κB 抑制剂，IC50=0.5 μM，是一种天然产物。它可抑制蛋白合成，降低 cyclin D1 蛋白水平，但对 TNFα 诱导的 IκBα 降解或 IKKα/β 和 IκBα 的磷酸化水平没有作用。
T4593	ISOPIMPINELLIN 5,8-Dimethoxypsoralen,异茴芹内酯,4,9-Dimethoxypsoralen	Antiviral; DNA/RNA Synthesis; Parasite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; Microbiology/Virology
	Isopimpinellin (4,9-Dimethoxypsoralen) 是从 Pimpinella saxifrage 根部分离得到的一种天然产物，具有抗病毒和抗利什曼病活性。
T9715	Aplidine	SARS-CoV; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Aplidine 是有效的eEF1A2(KD=80 nM) 靶向的抗癌药物。Aplidine 具有抗病毒活性，抑制SARS-CoV-2的 IC90为 0.88 nM。Aplidine 在多发性骨髓瘤，晚期癌症及 COVID-19 领域有研究的价值。
TN2132	Quinizarin 1,4-Dihydroxyanthraquinone,1,4-二羟基蒽醌	Others; DNA/RNA Synthesis; Antifungal	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others
	Quinizarin (1,4-Dihydroxyanthraquinone) 是一种杀菌剂和杀虫剂，可抑制肿瘤细胞生长。
T2998	Dihydromyricetin Ampelopsin,Ampeloptin,二氢杨梅素	Influenza Virus; GABA Receptor; DNA/RNA Synthesis; mTOR; Autophagy	Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; PI3K/Akt/mTOR signaling
	Dihydromyricetin (Ampelopsin) 是一种来自 Ampelopsis Grossedentata 的天然抗氧化剂类黄酮，是二氢嘧啶酶抑制剂，IC50 为 48 μM。它通过抑制mTOR 信号从而激活自噬。它还是流感依赖 RNA 的RNA 聚合酶抑制剂，IC50为 22 μM。
T0950	Neomycin sulfate Framycin sulfate,硫酸新霉素	Phospholipase; ribosome; Antibacterial; Antibiotic	Metabolism; Microbiology/Virology
	Neomycin sulfate (Framycin sulfate) 是一种广谱的氨基糖苷类抗生素。Neomycin sulfate 可以阻断细菌蛋白质的合成以发挥抗菌活性。Neomycin sulfate 常用于筛选具有 Neo 抗性基因的原核和真核细胞。
T1032	Erythromycin 红霉素,E-Mycin	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Erythromycin (E-Mycin) 是由放线菌产生的大环内酯类抗生素。它结合细菌的 50S 核糖体亚基，通过阻断转肽和易位反应来抑制 RNA 依赖性蛋白的合成。
TWP2911	Thymidine beta-胸苷,5-Methyldeoxyuridine,Deoxyribothymidine,DThyd,NSC 21548,Thymidin	Others; DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others
	Thymidine (DThyd) 是一种细胞同步剂，是脱氧核糖核酸的特殊前体。它可在 DNA 复制前在 G1/S 边界阻滞细胞，是DNA 合成抑制因子。
T8244	Raspberry ketone glucoside 覆盆子酮葡糖苷,树莓苷，覆盆子酮葡萄糖甙	Others	Others
	Raspberry ketone glucoside 是一种山莓果实中的天然产物。它能够抑制黑色素的合成。
T13791	N2-methylguanine 6-羟基-2-氨甲基嘌呤	DNA/RNA Synthesis; Endogenous Metabolite; Antibacterial	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	N2-methylguanine (N2-methylguanine) 是一种在人体体液中发现的内源性甲基化核苷，是一种修饰的核苷。
T0064	Adenine Vitamin B4,腺嘌呤,6-Aminopurine	DNA/RNA Synthesis; Endogenous Metabolite; AChR	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Neuroscience
	Adenine (6-Aminopurine) 是一种嘌呤衍生物，是一种核碱基。它在细胞呼吸、以富含能量的 ATP 和 NAD 和 FAD 的形式和蛋白质合成作用，作为 DNA 和 RNA 的化学成分。
TN1097	β-Boswellic acid Beta-boswellic acid,β-乳香酸	Lipoxygenase; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	β-Boswellic acid (Beta-boswellic acid) 是从乳香的树胶脂中分离出来的一种天然产物。它是 5-脂氧合酶(5-LO) 产物形成的非还原型抑制剂，其直接与 5-LO 相互作用或阻断其易位。具有抗癌、抗肿瘤和抗高血脂活性。
T7004	Tubercidin 结核菌素,杀结核菌素,Sparsomycin A,7-Deazaadenosine	Influenza Virus; DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Tubercidin (Sparsomycin A) 是从Streptomyces tubercidicus 得到的抗生素，抑制粪链球菌生长的IC50值为 0.02 μM。它是腺苷磷酸化酶的弱抑制剂，并干扰腺苷和 AMP 的磷酸化。它有抗病毒作用。
T0895	Oxytetracycline 土霉素,Terramycin	ribosome; Endogenous Metabolite; Antibacterial; Antibiotic; HSV	Metabolism; Microbiology/Virology
	Oxytetracycline (Terramycin) 是一种四环素类抗生素。它强力抑制革兰氏阴性和革兰氏阳性细菌。它是一种蛋白质合成抑制剂，可阻止 aminoacil-tRNA 与复杂的核糖体 RNA 结合，具有抗 HSV-1的活性。
T3343	5-methoxyflavone 5-methoxy-2-phenylchromen-4-one,5-甲氧基黄酮	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	5-methoxyflavone (5-methoxy-2-phenylchromen-4-one) 是一种类黄酮，是DNA 聚合酶 β 的抑制剂和 β-淀粉样蛋白毒性的神经保护剂。它通过调控嗜离子 GABAA 受体，起到镇静中枢神经系统的作用。
T6116	Bleomycin Sulfate Blenoxane,硫酸博来霉素,硫酸博莱霉素,NSC125066	DNA/RNA Synthesis; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Bleomycin Sulfate (Blenoxane) 是一种糖肽抗生素，一种 DNA 合成抑制剂。Bleomycin Sulfate 可以引起 DNA 链断裂而不引起 RNA 链断裂。Bleomycin Sulfate 具有抗肿瘤活性。
T6758	Anisomycin 茴香霉素,Flagecidin,NSC 76712,Wuningmeisu C	Apoptosis; DNA/RNA Synthesis; Antibacterial; Antibiotic; JNK	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; MAPK; Microbiology/Virology
	Anisomycin (Flagecidin) 属于细菌抗生素，是一种蛋白合成抑制剂和一种 JNK 激活剂。Anisomycin 通过抑制肽基转移酶或 80S 核糖体系统来干扰蛋白质和 DNA 的合成。
T1465	Mupirocin Pseudomonic acid,莫匹罗星,BRL-4910A	DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Mupirocin (BRL-4910A) 是从Pseudomonas fluorescens 中分离得到的一种有口服活性的抗生素。它可逆地抑制异亮氨酸转移RNA，并抑制细菌蛋白和RNA 的合成起抗菌作用。
T12045	(-)-Hydroxycitric acid lactone 藤黄内酯,Garcinia lactone	ATP Citrate Lyase	Metabolism
	(-)-Hydroxycitric acid lactone (Garcinia lactone) 是一种有效的 ATP-柠檬酸裂解酶抑制剂，能够催化柠檬酸盐线粒体外裂解为草酰乙酸和乙酰辅酶 A，限制了脂肪酸合成所需乙酰辅酶 A 单位的可用性。它是一种减肥药，是一种广受欢迎的减肥食品补充剂。
TN2111	Prunin Naringenin 7-0-glucoside,柚皮素-7-O-葡萄糖苷	Phosphatase; Anti-infection; Virus Protease	Metabolism; Microbiology/Virology
	Prunin (Naringenin 7-0-glucoside) 是一种人肠道病毒 A71 抑制剂。它抑制蛋白酪氨酸磷酸酶 1B，IC50值为 5.5 μM。
T7174	Urolithin A 尿石素A,3,8-二羟基-6H-二苯并[B,D]吡喃-6-酮	Apoptosis; Reactive Oxygen Species; DNA/RNA Synthesis; Endogenous Metabolite; Autophagy; Drug Metabolite	Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; NF-κB
	Urolithin A 是一种鞣花酸的肠道微生物代谢产物，可诱导自噬和凋亡，抑制细胞周期进程，抑制DNA 合成，具有抗炎、抗增殖和抗氧化的特性。
T38427	dUTP trisodium 2'-Deoxyuridine-5'-triphosphate trisodium salt,Deoxyuridine triphosphate	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	dUTP trisodium (Deoxyuridine triphosphate) 是在 5'-位具有三磷酸基团的脱氧尿苷磷酸盐，可用于 PCR。
T7094	Levomefolic Acid L-5-甲基四氢叶酸,5-MTHF,5-甲基四氢叶酸	Reactive Oxygen Species; Endogenous Metabolite	Immunology/Inflammation; Metabolism; NF-κB
	Levomefolic Acid (5-MTHF) 是一种具有口服活性、可穿过血脑屏障的天然活性叶酸，是广泛使用的叶酸食品补充剂。
T6567	Levofloxacin Levaquin,Cravit,Tavanic,Fluoroquinolone,左氧氟沙星,(-)-Ofloxacin	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Levofloxacin (Fluoroquinolone) 是合成的氟喹诺酮类抗生素，有抑制细菌DNA 旋转酶的超螺旋活性的作用，能阻止DNA 复制。
T0062	Folic acid Folate,Vitamin B9,Pteroylglutamic acid,Vitamin M,叶酸,Folacin	DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Folic acid (Vitamin B9) 是维生素B9，是合成DNA/RNA，新细胞产生和维持的必要成分。
T8148	Mupirocin calcium hydrate 莫匹罗星钙,Mupirocin calcium	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	Mupirocin calcium hydrate 是从Pseudomonas fluorescens 中分离得到的，一种有口服活性的抗生素。它可逆地抑制异亮氨酸转移RNA，并抑制细菌蛋白和RNA 的合成起到抗菌作用。
T6225	Adenine hydrochloride Adenine HCl,腺嘌呤盐酸盐,6-Aminopurine hydrochloride	DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Adenine hydrochloride (6-Aminopurine hydrochloride) 是一种嘌呤，是一种核碱基。它在细胞呼吸、以富含能量的 ATP 和 NAD 和 FAD 的形式和蛋白质合成作用，作为 DNA 和 RNA 的化学成分。
T14193	α-Galactosylceramide KRN7000,α-GalCer	Others	Others
	α-Galactosylceramide (KRN7000) 是一种具有抗肿瘤和免疫刺激作用的合成糖脂。它是一种高效的 NKT 细胞激动剂，可与 CD1d 有效结合。它与 CD1d 的复合物可与 NKT 细胞的 T 细胞抗原受体结合。
T6624	Oxytetracycline Dihydrate 土霉素二水合物,地霉素,Terramycin Dihydrate	Others; Endogenous Metabolite; Antibacterial; Antibiotic; HSV	Metabolism; Microbiology/Virology; Others
	Oxytetracycline Dihydrate (Terramycin Dihydrate) 是一种四环素类抗生素，可抑制革兰氏阴性和革兰氏阳性细菌。它是一种蛋白质合成抑制剂，可阻止 aminoacil-tRNA 与复杂的核糖体 RNA 结合，还具有抗 HSV-1的活性。
T0687	Simvastatin 辛伐他汀,MK-0733,MK 733	Apoptosis; Mitophagy; Ferroptosis; HMG-CoA Reductase; Autophagy	Apoptosis; Autophagy; Metabolism
	Simvastatin (MK 733) 是一种 HMG-CoA 还原酶抑制剂 (Ki=0.2 nM)，具有口服活性。Simvastatin 具有降血脂活性，可以抑制肝脏产生胆固醇，还可以用于预防心血管疾病。
T0974	Novobiocin Sodium Albamycinsodium,新生霉素钠,Cathomycin,Albamycin	Potassium Channel; DNA gyrase; Topoisomerase; Antibacterial; Antibiotic; ABC; Autophagy	Autophagy; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Microbiology/Virology
	Novobiocin Sodium (Albamycinsodium) 是源自 Streptomyces niveus 的抗生素。它的化学结构类似于香豆素。Novobiocin 与 DNA 促旋酶结合并阻断三磷酸腺苷活性。
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天然产物

Deoxycytidine triphosphate

Cat.No: T7520

Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Endogenous Metabolite

Xanthopterin (hydrate)

Cat.No: T13969

Target: Others, DNA/RNA Synthesis

Sodium Camptothecin

Cat.No: T40179

Target: DNA/RNA Synthesis

5-Methylcytosine

Cat.No: T5270

Target: Others, DNA/RNA Synthesis, Endogenous Metabolite

Cat.No: T2S1635

Target: MTH1

Cat.No: TN1134

Target: Apoptosis, LDL, PI3K, DNA/RNA Synthesis, NO Synthase, Prostaglandin Receptor

3-Hydroxy-2-methylpyridine

Cat.No: T5901

Target: Others

Cat.No: T21498

Target: DNA/RNA Synthesis, Antibacterial, Antibiotic

Cat.No: T1068

Synonym: 1,8,9-trihydroxyanthracene,cignoline,蒽林,Anthralin

Target: Others, DNA/RNA Synthesis

1-Hydroxyanthraquinone

Cat.No: T37101

Target: DNA/RNA Synthesis

Cat.No: T7529

Synonym: 山药

Target: Others

4-Hydroxyflavanone

Cat.No: T7992

Target: NO Synthase

N-Nitrosodiethylamine

Cat.No: T35455

Synonym: Diethylnitrosamine,NDEA

Target: DNA/RNA Synthesis

Chebulinic acid

Cat.No: TQ0184

Target: ATPase, Proton pump, DNA/RNA Synthesis, Antibacterial, TGF-beta/Smad

Cat.No: T13229

Target: Influenza Virus, Antibacterial, Antibiotic, Antifungal

Cat.No: T6S0232

Synonym: 圣草酚,Huazhongilexone

Target: Influenza Virus, DNA/RNA Synthesis, Nrf2, Endogenous Metabolite

Neobavaisoflavone

Cat.No: T6S0139

Target: Apoptosis, DNA/RNA Synthesis

Cat.No: T20945

Synonym: Hedonal,Macondray,2,4-D acid,Chloroxone,2,4-二氯苯氧乙酸

Target: DNA/RNA Synthesis

Cat.No: T16674

Target: Endogenous Metabolite

Eurycomalactone

Cat.No: TN1637

Target: Anti-infection, NF-κB

Cat.No: T4593

Synonym: 5,8-Dimethoxypsoralen,异茴芹内酯,4,9-Dimethoxypsoralen

Target: Antiviral, DNA/RNA Synthesis, Parasite

Cat.No: T9715

Target: SARS-CoV, DNA/RNA Synthesis

Cat.No: TN2132

Synonym: 1,4-Dihydroxyanthraquinone,1,4-二羟基蒽醌

Target: Others, DNA/RNA Synthesis, Antifungal

Dihydromyricetin

Cat.No: T2998

Synonym: Ampelopsin,Ampeloptin,二氢杨梅素

Target: Influenza Virus, GABA Receptor, DNA/RNA Synthesis, mTOR, Autophagy

Neomycin sulfate

Cat.No: T0950

Synonym: Framycin sulfate,硫酸新霉素

Target: Phospholipase, ribosome, Antibacterial, Antibiotic

Cat.No: T1032

Synonym: 红霉素,E-Mycin

Target: ribosome, Antibacterial, Antibiotic

Cat.No: TWP2911

Synonym: beta-胸苷,5-Methyldeoxyuridine,Deoxyribothymidine,DThyd,NSC 21548,Thymidin

Target: Others, DNA/RNA Synthesis, Endogenous Metabolite

Raspberry ketone glucoside

Cat.No: T8244

Synonym: 覆盆子酮葡糖苷,树莓苷，覆盆子酮葡萄糖甙

Target: Others

N2-methylguanine

Cat.No: T13791

Synonym: 6-羟基-2-氨甲基嘌呤

Target: DNA/RNA Synthesis, Endogenous Metabolite, Antibacterial

Cat.No: T0064

Synonym: Vitamin B4,腺嘌呤,6-Aminopurine

Target: DNA/RNA Synthesis, Endogenous Metabolite, AChR

β-Boswellic acid

Cat.No: TN1097

Synonym: Beta-boswellic acid,β-乳香酸

Target: Lipoxygenase, DNA/RNA Synthesis

Cat.No: T7004

Synonym: 结核菌素,杀结核菌素,Sparsomycin A,7-Deazaadenosine

Target: Influenza Virus, DNA/RNA Synthesis, Antibacterial, Antibiotic

Oxytetracycline

Cat.No: T0895

Synonym: 土霉素,Terramycin

Target: ribosome, Endogenous Metabolite, Antibacterial, Antibiotic, HSV

5-methoxyflavone

Cat.No: T3343

Synonym: 5-methoxy-2-phenylchromen-4-one,5-甲氧基黄酮

Target: DNA/RNA Synthesis

Bleomycin Sulfate

Cat.No: T6116

Synonym: Blenoxane,硫酸博来霉素,硫酸博莱霉素,NSC125066

Target: DNA/RNA Synthesis, Antibiotic

Cat.No: T6758

Synonym: 茴香霉素,Flagecidin,NSC 76712,Wuningmeisu C

Target: Apoptosis, DNA/RNA Synthesis, Antibacterial, Antibiotic, JNK

Cat.No: T1465

Synonym: Pseudomonic acid,莫匹罗星,BRL-4910A

Target: DNA/RNA Synthesis, Antibacterial, Antibiotic

(-)-Hydroxycitric acid lactone

Cat.No: T12045

Synonym: 藤黄内酯,Garcinia lactone

Target: ATP Citrate Lyase

Cat.No: TN2111

Synonym: Naringenin 7-0-glucoside,柚皮素-7-O-葡萄糖苷

Target: Phosphatase, Anti-infection, Virus Protease

Cat.No: T7174

Synonym: 尿石素A,3,8-二羟基-6H-二苯并[B,D]吡喃-6-酮

Target: Apoptosis, Reactive Oxygen Species, DNA/RNA Synthesis, Endogenous Metabolite, Autophagy, Drug Metabolite

Cat.No: T38427

Synonym: 2'-Deoxyuridine-5'-triphosphate trisodium salt,Deoxyuridine triphosphate

Target: DNA/RNA Synthesis

Levomefolic Acid

Cat.No: T7094

Synonym: L-5-甲基四氢叶酸,5-MTHF,5-甲基四氢叶酸

Target: Reactive Oxygen Species, Endogenous Metabolite

Cat.No: T6567

Synonym: Levaquin,Cravit,Tavanic,Fluoroquinolone,左氧氟沙星,(-)-Ofloxacin

Target: Topoisomerase, Antibacterial, Antibiotic

Cat.No: T0062

Synonym: Folate,Vitamin B9,Pteroylglutamic acid,Vitamin M,叶酸,Folacin

Target: DNA/RNA Synthesis, Endogenous Metabolite

Mupirocin calcium hydrate

Cat.No: T8148

Synonym: 莫匹罗星钙,Mupirocin calcium

Target: Others, Antibacterial, Antibiotic

Adenine hydrochloride

Cat.No: T6225

Synonym: Adenine HCl,腺嘌呤盐酸盐,6-Aminopurine hydrochloride

Target: DNA/RNA Synthesis, Endogenous Metabolite

α-Galactosylceramide

Cat.No: T14193

Synonym: KRN7000,α-GalCer

Target: Others

Oxytetracycline Dihydrate

Cat.No: T6624

Synonym: 土霉素二水合物,地霉素,Terramycin Dihydrate

Target: Others, Endogenous Metabolite, Antibacterial, Antibiotic, HSV

Cat.No: T0687

Synonym: 辛伐他汀,MK-0733,MK 733

Target: Apoptosis, Mitophagy, Ferroptosis, HMG-CoA Reductase, Autophagy

Novobiocin Sodium

Cat.No: T0974

Synonym: Albamycinsodium,新生霉素钠,Cathomycin,Albamycin

Target: Potassium Channel, DNA gyrase, Topoisomerase, Antibacterial, Antibiotic, ABC, Autophagy

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03221	Intrinsic Factor Protein, Human, Recombinant (His) IF,IFMH,gastric intrinsic factor (vitamin B synthesis	Human	HEK293 Cells
	Gastric intrinsic factor, also known as GIF, belongs to the of the cobalamin transport protein family. It is a glycoprotein produced by the parietal cells of the stomach. Gastric intrinsic factor plays a key role in the absorption of vitamin B12 on in the small intestine. Vitamin B12 bounds to haptocorrin after entry into the stomach. The resulting complex enters the duodenum, where pancreatic enzymes digest haptocorrin. In the less acidic environment of the small intestine, B12 can then bind to...
TMPH-00659	FlgM Protein, E. coli, Recombinant (His & Myc) Negative regulator of flagellin synthesis,flgM,Anti...	E. coli	E. coli
	Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA. FlgM Protein, E. coli, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 17.8 kDa and the accession number is P0AEM4.
TMPH-03453	GPI3 Protein, S. cerevisiae, Recombinant (His & Myc) Phosphatidylinositol N-acetylglucosaminyltransferase GPI3 su...	Saccharomyces cerevisiae	E. coli
	Catalytic subunit in the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. GPI3 Protein, S. cerevisiae, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 49.8 kDa and the accession number is P32363.
TMPH-00735	LuxS Protein, E. coli, Recombinant (His & Myc) luxS,S-ribosylhomocysteine lyase,Autoinducer-2 production pr...	E. coli	E. coli
	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
TMPH-00734	LuxS Protein, E. coli, Recombinant (His) AI-2 synthesis protein,Autoinducer-2 production pro...	E. coli	E. coli
	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). LuxS Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. Th...
TMPH-00711	BioH Protein, E. coli, Recombinant (His & Myc) bioB,Carboxylesterase BioH,Biotin synthesis protein...	E. coli	E. coli
	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. E.coli employs a methylation and demethylation strategy to allow elongation of a temporarily disguised malonate moiety to a pimelate moiety by the fatty acid synthetic enzymes. BioH shows a preference for short chain fatty acid esters (acyl c...
TMPJ-01172	IL-17 Protein, Mouse, Recombinant (His) CTLA8,IL-17,IL-17A,Interleukin-17A,CTLA-8,Cytotoxic T-Lympho...	Mouse	HEK293 Cells
	Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Mature mouse IL-17A shares 61% and 89% amino acid sequence identity with human and rat IL-17A, respectively. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumato...
TMPH-00007	HMGCR Protein, Human, Recombinant (His) HMGCR,3-hydroxy-3-methylglutaryl-coenzyme A reductase	Human	E. coli
	Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis. HMGCR is the main target of statins, a class of cholesterol-lowering drugs.
TMPY-02543	PCNA Protein, Human, Recombinant (His) ATLD2,proliferating cell nuclear antigen	Human	Baculovirus Insect Cells
	Proliferating Cell Nuclear Antigen (PCNA) is a protein only expressed in normal proliferate cells and cancer cells. It is central to both DNA replication and repair. One of the well-established functions for PCNA is its role as the processivity factor for DNA polymerase delta and epsilon. PCNA tethers the polymerase catalytic unit to the DNA template for rapid and processive DNA synthesis. Two forms of PCNA exist in cells: (i) a detergent-insoluble trimeric form stably associated with the replic...
TMPY-00545	Dermcidin Protein, Human, Recombinant (hFc) AIDD,PIF,HCAP,dermcidin,DCD-1,DSEP	Human	HEK293 Cells
	Hepatocellular carcinoma (HCC) is a major contributor to cancer-related deaths due to its often late stage diagnosis, and dermcidin (DCD) may have the potential to be used as a serum biomarker for HCC for more timely diagnoses. Human dermcidin (DCD) is an antimicrobial peptide secreted constitutively by sweat glands. And the role of DCD in ischemic heart disease has drawn increasing attention in particular its relationship with insulin secretion and glycemic control, nitric oxide (NO) synthesis ...
TMPY-02483	ATP citrate lyase/ACLY Protein, Human, Recombinant (His) ATPCL,ACL,ATP citrate lyase,CLATP	Human	Baculovirus Insect Cells
	ATP citrate lyase, also known as Acly or Acl, is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is composed of two polymer chains which are polypeptides in human. ATP citrate lyase is responsible for catalyzing the conversion of citrate and CoA into acetyl-CoA and oxaloacetate, along with the hydrolysis of ATP. A definitive role for ATP citrate lyase in tumorigenesis has emerged from ATP citrate lyase RNAi and chemical inhibitor studies, show...
TMPY-03650	BirA Protein, E. coli, Recombinant (His & MBP) BirA,dhbB,bioR	E. coli	E. coli
	The enzyme BirA is a key reagent because of its ability to biotinylate proteins at a specific residue in a recognition sequence. This enzyme is used to biotinylate the C termini of membrane proteins, allowing these proteins to be tetramerized by binding to streptavidin. Because of the specificity of the biotinylation at the C terminus, the orientation of the membrane proteins on the streptavidin is equivalent to that of the native protein on the cell surface. These tetrameric proteins can be use...
TMPY-01101	Coagulation factor X/F10 Protein, Human, Recombinant (His) FXA,FX,coagulation factor X,coagulation factor 10	Human	Baculovirus Insect Cells
	Coagulation factor X, also known as FX, F10, Eponym Stuart-Prower factor, and thrombokinase, is an enzyme of the coagulation cascade. It is one of the vitamin K-dependent serine proteases, and plays a crucial role in the coagulation cascade and blood clotting, as the first enzyme in the common pathway of thrombus formation. Factor X deficiency is one of the rarest of the inherited coagulation disorders. FX deficiency among the most severe of the rare coagulation defects, typically including hema...
TMPH-00608	Dihydrofolate reductase Protein, E. coli, Recombinant (His) Dihydrofolate reductase,folA,tmrA	E. coli	E. coli
	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
TMPH-01224	Dihydrofolate reductase Protein, Human, Recombinant (His) DHFR,Dihydrofolate reductase	Human	E. coli
	Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFR2.
TMPH-01561	ISCU Protein, Human, Recombinant (His & Myc) NifU-like protein,ISCU,Iron-sulfur cluster assembly enzyme I...	Human	Baculovirus Insect Cells
	Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic Functions as a cytoplasmic scaffold protein for the de novo synthesis of iron-sulfur clusters in the cytoplasm.
TMPH-03714	HAS1 Protein, Xenopus tropicalis, Recombinant (His & Myc) Hyaluronic acid synthase 1,has1,Hyaluronan synthase 1,Hyalur...	Xenopus tropicalis	E. coli
	Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. Also able to catalyze the synthesis of chito-oligosaccharide depending on the substrate.
TMPH-01211	DGUOK Protein, Human, Recombinant (His & SUMO) Deoxyguanosine kinase, mitochondrial,Deoxyadenosine kinase, ...	Human	E. coli
	Phosphorylates deoxyguanosine and deoxyadenosine in the mitochondrial matrix, with the highest efficiency for deoxyguanosine. In non-replicating cells, where cytosolic dNTP synthesis is down-regulated, mtDNA synthesis depends solely on DGUOK and TK2. Phosphorylates certain nucleoside analogs. Widely used as target of antiviral and chemotherapeutic agents.
TMPH-03581	Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His) dfrC,folA1,Dihydrofolate reductase,folA,DHFR	Staphylococcus epidermidis	E. coli
	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 22.0 kDa and the accession number is P0C0P1.
TMPH-00515	PPDK Protein, Entamoeba histolytica, Recombinant (His & SUMO) PPDK,Pyruvate, orthophosphate dikinase,Pyruvate, phosphate d...	Entamoeba histolytica	E. coli
	Catalyzes the reversible phosphorylation of pyruvate and phosphate. In E.histolytica and C.symbiosus, PPDK functions in the direction of ATP synthesis.
TMPH-02383	Lake Victoria marburgvirus (MARV) (strain Musoke-80) VP35 Protein (His) Polymerase cofactor VP35,VP35,Marburg VP35	MARV	E. coli
	Plays an essential role in viral RNA synthesis and also a role in suppressing innate immune signaling.
TMPH-03055	Ribonuclease mitogillin Protein, Neosartorya fumigata, Recombinant (His & Myc & SUMO) Major allergen Asp f 1,Allergen Asp f I,Ribonuclease mitogil...	Neosartorya fumigata	E. coli
	This purine-specific ribonuclease cleaves 28S RNA in eukaryotic ribosomes, inhibits protein synthesis, and shows antitumor activity.
TMPY-05749	SARS-CoV-2 NSP8 Protein (Avi)	SARS-CoV-2	E. coli
	NSP8 is a nonstructural protein of coronavirus. NSP8 acts as a primase in RNA synthesis. NSP8 and NSP7 are essential co-factors of NSP12 (the catalytic subunit with RNA-dependent RNA polymerase activity) that can remarkably stimulate RdRp activity. The nsp12-nsp7-nsp8 subcomplex is defined as the minimal core component for mediating coronavirus RNA synthesis. SARS-CoV-2 NSP8 Protein (Avi) is expressed in E. coli expression system. The predicted molecular weight is 24.17 kDa and the accession num...
TMPH-03535	Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc) DHFR,Dihydrofolate reductase,folA	Staphylococcus aureus	E. coli
	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 25.6 kDa and the accession number is P99079.
TMPJ-00937	RRM2 Protein, Human, Recombinant (His) RRM2,RR2,Ribonucleotide Reductase Small Subunit,Ribonucleoti...	Human	HEK293 Cells
	Ribonucleoside-Diphosphate Reductase Subunit M2 (RRM2) belongs to the ribonucleoside diphosphate reductase small chain family. The reductase of RRM2 catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. RRM2 supplies the precursors essential for DNA synthesis. RRM2 catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Phosphorylation on Ser-20 relieves the in...
TMPK-00958	BTN1A1 Protein, Human, Recombinant (His & Avi) BT,BTN,Butyrophilin,BTN1A1	Human	HEK293 Cells
	Butyrophilin 1A1 (BTN1A1) is one of the membrane proteins that surrounds LD,BTN1A1 plays an important role in regulating LD synthesis via a mechanism involving membrane phospholipid composition.
TMPH-03431	ACC1 Protein, S. cerevisiae, Recombinant (aa 217-775, His) Acetyl-CoA carboxylase,ACC,Fatty acid synthetase 3,mRNA tran...	Saccharomyces cerevisiae	E. coli
	Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nuclear envelope. Required for acylation and vacuolar membrane association of VAC8 which is necessary to maintain a normal morphology of the vacuole. ACC1 Protein, S. cerevisiae, Recombinant (aa 217-775, His) is expressed in E. coli expression system with N-10xHis tag. The predicted m...
TMPJ-01257	PMM1 Protein, Human, Recombinant (His) PMMH22,PMM 1,PMMH-22,PMM1,Phosphomannomutase 1	Human	E. coli
	Phosphomannomutase 1 (PMM1) blongs to the eukaryotic PMM family. Phosphomannomutase 1 can catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose which required for a number of critical mannosyl transfer reactions. PMM1 is highly expressed in liver, heart, brain, and pancreas, but lower expression in skeletal muscle. In addition, PMM1 may be responsible for the...
TMPY-05024	Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-NS5 protein (His)	ZIKV	Baculovirus Insect Cells
	Zika virus NS5 is involved in methytransferase and RNA guanylytransferase activities and capping and synthesis of RNA. And, NS5 is also an RNA-dependent RNA polymerase.
TMPH-00529	UvsY Protein, Enterobacteria phage T4, Recombinant (Avi & His) uvsY,Recombination protein uvsY	Enterobacteria phage T4	E. coli
	Plays a role in viral DNA synthesis by promoting enzymatic activities of UvsX recombinase, by promoting UvsX-ssDNA filament assembly, and by helping UvsX to displace bound gp32 from ssDNA.
TMPH-00663	APT Protein, E. coli O139:H28, Recombinant (His & Myc) APRT,apt,Adenine phosphoribosyltransferase	E. coli	E. coli
	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
TMPH-03524	KAS III Protein, S. aureus, Recombinant (His & Myc) 3-oxoacyl-[acyl-carrier-protein] synthase 3,3-oxoacyl-[acyl-...	Staphylococcus aureus	E. coli
	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids. KAS III Protein, S. au...
TMPH-01584	KRT7 Protein, Human, Recombinant (His & SUMO) KRT7,Keratin, type II cytoskeletal 7,Sarcolectin,Keratin-7,T...	Human	E. coli
	Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
TMPH-03432	ACC1 Protein, S. cerevisiae, Recombinant (aa 2-581, His) mRNA transport-defective protein 7,Acetyl-CoA carboxylase,Fa...	Saccharomyces cerevisiae	E. coli
	Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nuclear envelope. Required for acylation and vacuolar membrane association of VAC8 which is necessary to maintain a normal morphology of the vacuole. ACC1 Protein, S. cerevisiae, Recombinant (aa 2-581, His) is expressed in E. coli expression system with N-10xHis tag. The predicted mol...
TMPY-06416	SARS-CoV-2 NSP8 Protein	SARS-CoV-2	E. coli
	NSP8 is a nonstructural protein of coronavirus. NSP8 acts as a primase in RNA synthesis. NSP8 and NSP7 are essential co-factors of NSP12 (the catalytic subunit with RNA-dependent RNA polymerase activity) that can remarkably stimulate RdRp activity. The nsp12-nsp7-nsp8 subcomplex is defined as the minimal core component for mediating coronavirus RNA synthesis. SARS-CoV-2 NSP8 Protein is expressed in E. coli expression system. The predicted molecular weight is 22.04 kDa and the accession number is...
TMPH-02882	NQO2 Protein, Mouse, Recombinant (His) Ribosyldihydronicotinamide dehydrogenase [quinone],Quinone r...	Mouse	P. pastoris (Yeast)
	The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.
TMPH-00578	NrdD Protein, E. coli, Recombinant (His) nrdD,Class III ribonucleoside-triphosphate reductase,Anaerob...	E. coli	E. coli
	Catalyzes the conversion of ribonucleotides into deoxyribonucleotides, which are required for DNA synthesis and repair. NrdD Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 84.0 kDa and the accession number is P28903.
TMPJ-00905	DTYMK Protein, Human, Recombinant (His) DTYMK,TMPK,dTMP kinase,Thymidylate kinase,CDC8,TYMK	Human	HEK293 Cells
	Thymidylate kinase (DTYMK) is a ubiquitous enzyme of about 25 kD which belongs to thymidylate kinase family. DTYMK is important in the dTTP synthesis pathway for DNA synthesis. It participated in the pyrimidine metabolism pathway and dTTP biosynthesis pathway. DTYMK catalyzes the conversion of dTMP to dTDP and catalyzes the phosphorylation of thymidine 5'-monophosphate (dTMP) to form thymidine 5'-diphosphate (dTDP) in the presence of ATP and magnesium. Structural and functional analyses suggest ...
TMPY-03605	Glutaredoxin 1/GRX1 Protein, Human, Recombinant (His) GLRX,GRX,GRX1,glutaredoxin	Human	E. coli
	Glutaredoxin-1, also known as GRX1 and GLRX, belongs to theglutaredoxin family. Glutaredoxinsare smallredoxenzymes that useglutathioneas a cofactor. Glutaredoxins are oxidized by substrates, and reduced non-enzymatically by glutathione. Glutaredoxin-1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. Glutaredoxin-1 exists in either a reduced or an oxidized form. Glutaredoxins function as electron carriers ...
TMPH-02568	CTGF/CCN2 Protein, Mouse, Recombinant (GST) betaIG-M2,Connective tissue growth factor,Protein FISP-12,Fi...	Mouse	E. coli
	Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.
TMPH-00422	Ppdk Protein, Clostridium symbiosum, Recombinant (His & Myc) ppdK,Pyruvate, orthophosphate dikinase,Pyruvate, phosphate d...	Clostridium symbiosum	E. coli
	Catalyzes the reversible phosphorylation of pyruvate and phosphate. In E.histolytica and C.symbiosus, PPDK functions in the direction of ATP synthesis. Ppdk Protein, Clostridium symbiosum, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 20.5 kDa and the accession number is P22983.
TMPH-00171	PBP 4A Protein, Bacillus subtilis, Recombinant (His & SUMO) PBP 4A,pbpE,Penicillin-binding protein E,Penicillin-binding ...	Bacillus subtilis	E. coli
	Probably involved in peptidoglycan modification during cortex synthesis. PBP 4A Protein, Bacillus subtilis, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 67.4 kDa and the accession number is P32959.
TMPH-01085	CHAT Protein, Human, Recombinant (His) CHAT,Choline O-acetyltransferase,ChAT,CHOACTase,Choline acet...	Human	E. coli
	Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses. CHAT Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 72.7 kDa and the accession number is P28329.
TMPH-00131	Ribonuclease mitogillin Protein, Aspergillus restrictus, Recombinant (His & Myc) Ribonuclease mitogillin,Restrictocin,ret	Aspergillus restrictus	E. coli
	This purine-specific ribonuclease cleaves 28S RNA in eukaryotic ribosomes, inhibits protein synthesis, and shows antitumor activity. Ribonuclease mitogillin Protein, Aspergillus restrictus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 23.9 kDa and the accession number is P67876.
TMPK-01308	TAG-72 Protein, Canine, Recombinant (His) mRNA-methyltransferase,mRNA (guanine-N(7))-methyltransferase...	Canine	E. coli
	The guanine-N7 methyltransferase domain of vaccinia virus mRNA capping enzyme is a heterodimer composed of a catalytic subunit and a stimulatory subunit. Cap (guanine-N7) methylation is an essential step in eukaryal mRNA synthesis and a potential target for antiviral, antifungal, and antiprotozoal drug discovery.
TMPK-01386	TK1 Potein, Canine, Recombinant (His) thymidine kinase-1,EC 2.7.1.21,Thymidine kinase	Canine	E. coli
	Thymidine kinase 1 (TK1) catalyzes the initial phosphorylation of thymidine in the salvage pathway synthesis of dTTP, an essential building block of DNA. TK1 is a cytosolic enzyme with its highest level during the S-phase of the cell cycle.
TMPH-00648	LapB Protein, E. coli, Recombinant (His) Lipopolysaccharide assembly protein B,lapB,Lipopolysaccharid...	E. coli	E. coli
	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.
TMPH-00157	Thymidylate kinase Protein, Bacillus anthracis, Recombinant (His) dTMP kinase,tmk,Thymidylate kinase	Bacillus anthracis	E. coli
	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. Thymidylate kinase Protein, Bacillus anthracis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 27.8 kDa and the accession number is C3LJ02.
TMPJ-01408	HDGFRP3 Protein, Human, Recombinant (His) HDGF2,HRP-3,HDGF-2,Hepatoma-Derived Growth Factor-Related Pr...	Human	HEK293 Cells
	Hepatoma-Derived Growth Factor-Related Protein 3 (HDGFRP3) belongs to the HDGF family. HDGFRP3 can be found in testis, heart, spinal cord and brain. HDGFRP3 localizes to the nucleus and contains one PWWP domain. HDGFRP3 enhances DNA synthesis and may have a role in cell proliferation.
TMPH-02797	NQO1 Protein, Mouse, Recombinant (His) Quinone reductase 1,NAD(P)H dehydrogenase [quinone] 1,NAD(P)...	Mouse	P. pastoris (Yeast)
	The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. NQO1 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 32.8 kDa and the accession number is Q64669.
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重组蛋白

Intrinsic Factor Protein, Human, Recombinant (His)

Cat.No: TMPY-03221

Species: Human

Expression System: HEK293 Cells

FlgM Protein, E. coli, Recombinant (His & Myc)

Cat.No: TMPH-00659

Species: E. coli

Expression System: E. coli

GPI3 Protein, S. cerevisiae, Recombinant (His & Myc)

Cat.No: TMPH-03453

Species: Saccharomyces cerevisiae

Expression System: E. coli

LuxS Protein, E. coli, Recombinant (His & Myc)

Cat.No: TMPH-00735

Species: E. coli

Expression System: E. coli

LuxS Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00734

Species: E. coli

Expression System: E. coli

BioH Protein, E. coli, Recombinant (His & Myc)

Cat.No: TMPH-00711

Species: E. coli

Expression System: E. coli

IL-17 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01172

Species: Mouse

Expression System: HEK293 Cells

HMGCR Protein, Human, Recombinant (His)

Cat.No: TMPH-00007

Species: Human

Expression System: E. coli

PCNA Protein, Human, Recombinant (His)

Cat.No: TMPY-02543

Species: Human

Expression System: Baculovirus Insect Cells

Dermcidin Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00545

Species: Human

Expression System: HEK293 Cells

ATP citrate lyase/ACLY Protein, Human, Recombinant (His)

Cat.No: TMPY-02483

Species: Human

Expression System: Baculovirus Insect Cells

BirA Protein, E. coli, Recombinant (His & MBP)

Cat.No: TMPY-03650

Species: E. coli

Expression System: E. coli

Coagulation factor X/F10 Protein, Human, Recombinant (His)

Cat.No: TMPY-01101

Species: Human

Expression System: Baculovirus Insect Cells

Dihydrofolate reductase Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00608

Species: E. coli

Expression System: E. coli

Dihydrofolate reductase Protein, Human, Recombinant (His)

Cat.No: TMPH-01224

Species: Human

Expression System: E. coli

ISCU Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01561

Species: Human

Expression System: Baculovirus Insect Cells

HAS1 Protein, Xenopus tropicalis, Recombinant (His & Myc)

Cat.No: TMPH-03714

Species: Xenopus tropicalis

Expression System: E. coli

DGUOK Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01211

Species: Human

Expression System: E. coli

Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His)

Cat.No: TMPH-03581

Species: Staphylococcus epidermidis

Expression System: E. coli

PPDK Protein, Entamoeba histolytica, Recombinant (His & SUMO)

Cat.No: TMPH-00515

Species: Entamoeba histolytica

Expression System: E. coli

Lake Victoria marburgvirus (MARV) (strain Musoke-80) VP35 Protein (His)

Cat.No: TMPH-02383

Species: MARV

Expression System: E. coli

Ribonuclease mitogillin Protein, Neosartorya fumigata, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-03055

Species: Neosartorya fumigata

Expression System: E. coli

SARS-CoV-2 NSP8 Protein (Avi)

Cat.No: TMPY-05749

Species: SARS-CoV-2

Expression System: E. coli

Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc)

Cat.No: TMPH-03535

Species: Staphylococcus aureus

Expression System: E. coli

RRM2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00937

Species: Human

Expression System: HEK293 Cells

BTN1A1 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00958

Species: Human

Expression System: HEK293 Cells

ACC1 Protein, S. cerevisiae, Recombinant (aa 217-775, His)

Cat.No: TMPH-03431

Species: Saccharomyces cerevisiae

Expression System: E. coli

PMM1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01257

Species: Human

Expression System: E. coli

Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-NS5 protein (His)

Cat.No: TMPY-05024

Species: ZIKV

Expression System: Baculovirus Insect Cells

UvsY Protein, Enterobacteria phage T4, Recombinant (Avi & His)

Cat.No: TMPH-00529

Species: Enterobacteria phage T4

Expression System: E. coli

APT Protein, E. coli O139:H28, Recombinant (His & Myc)

Cat.No: TMPH-00663

Species: E. coli

Expression System: E. coli

KAS III Protein, S. aureus, Recombinant (His & Myc)

Cat.No: TMPH-03524

Species: Staphylococcus aureus

Expression System: E. coli

KRT7 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01584

Species: Human

Expression System: E. coli

ACC1 Protein, S. cerevisiae, Recombinant (aa 2-581, His)

Cat.No: TMPH-03432

Species: Saccharomyces cerevisiae

Expression System: E. coli

SARS-CoV-2 NSP8 Protein

Cat.No: TMPY-06416

Species: SARS-CoV-2

Expression System: E. coli

NQO2 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02882

Species: Mouse

Expression System: P. pastoris (Yeast)

NrdD Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00578

Species: E. coli

Expression System: E. coli

DTYMK Protein, Human, Recombinant (His)

Cat.No: TMPJ-00905

Species: Human

Expression System: HEK293 Cells

Glutaredoxin 1/GRX1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03605

Species: Human

Expression System: E. coli

CTGF/CCN2 Protein, Mouse, Recombinant (GST)

Cat.No: TMPH-02568

Species: Mouse

Expression System: E. coli

Ppdk Protein, Clostridium symbiosum, Recombinant (His & Myc)

Cat.No: TMPH-00422

Species: Clostridium symbiosum

Expression System: E. coli

PBP 4A Protein, Bacillus subtilis, Recombinant (His & SUMO)

Cat.No: TMPH-00171

Species: Bacillus subtilis

Expression System: E. coli

CHAT Protein, Human, Recombinant (His)

Cat.No: TMPH-01085

Species: Human

Expression System: E. coli

Ribonuclease mitogillin Protein, Aspergillus restrictus, Recombinant (His & Myc)

Cat.No: TMPH-00131

Species: Aspergillus restrictus

Expression System: E. coli

TAG-72 Protein, Canine, Recombinant (His)

Cat.No: TMPK-01308

Species: Canine

Expression System: E. coli

TK1 Potein, Canine, Recombinant (His)

Cat.No: TMPK-01386

Species: Canine

Expression System: E. coli

LapB Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00648

Species: E. coli

Expression System: E. coli

Thymidylate kinase Protein, Bacillus anthracis, Recombinant (His)

Cat.No: TMPH-00157

Species: Bacillus anthracis

Expression System: E. coli

HDGFRP3 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01408

Species: Human

Expression System: HEK293 Cells

NQO1 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02797

Species: Mouse

Expression System: P. pastoris (Yeast)

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Cat. No.	Product Name	Target	Signaling Pathways
T38035	Phenol-13C6 Phenol-13C6
	Phenol-13C6is a building block.1It has been used in the synthesis of13C6-labeled metabolites of (±)-asenapine . 1.Kuethe, J.T.Synthesis of stable isotope‐labeled metabolites of asenapineJ. Labelled Comp. Radiopharm.55(5)180-185(2012)
T10992	Delamanid D4 OPC-67683 D4	Others	Others
	Delamanid D4 is deuterium-labeled Delamanid. Delamanid is a newer mycobacterial cell wall synthesis inhibitor that inhibits the synthesis of mucus acid.
T11853	Linezolid-d3 Linezolid D3,PNU-100766 D3	Others	Others
	Linezolid D3, a deuterium-labeled version of Linezolid, is a synthetic antibiotic designed to halt the initiation of bacterial protein synthesis.
T13028	Sulfamerazine D4	Others	Others
	Sulfamerazine D4, a deuterium-labeled version of Sulfamerazine, acts as a sulfonamide antibacterial. It inhibits the bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for the binding site on dihydropteroate synthase.
T36895	5-Fluorouracil-13C,15N2 5-Fluorouracil-13C,15N2
	5-Fluorouracil-13C,15N2 is intended for use as an internal standard for the quantification of 5-flurouracil by GC- or LC-MS. 5-Fluorouracil is a pyrimidine analog that irreversibly inhibits thymidylate synthase, blocking the synthesis of thymidine which is required for DNA synthesis. Intracellular metabolites of 5-fluorouracil exert cytotoxic effects by either inhibiting thymidylate synthetase, or through incorporation into RNA and DNA, ultimately initiating apoptosis.
T39441	L-Arginine-15N4 hydrochloride L-Arginine-15N4 hydrochloride,(S)-(+)-Arginine-15N4 hydrochloride
	L-Arginine-15N4 ((S)-(+)-Arginine-15N4) hydrochloride, the 15N-labeled variant of L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride), serves as the nitrogen donor in the synthesis of nitric oxide. This potent vasodilator is crucial, especially during a sickle cell crisis where its levels are notably diminished.
TMIH-0457	Proguanil-d6 HCl
	Proguanil-d6 HCl 是 Proguanil HCl 的氘代化合物。Proguanil HCl 的 CAS 号为 637-32-1。Proguanil hydrochloride 是一种双胍类抗疟疾剂，在体内代谢形成环胍。它还是一种二氢叶酸还原酶抑制剂。
TMID-0087	Azathioprine-d3
	Azathioprine-d3 是 Azathioprine 的氘代化合物。Azathioprine 的 CAS 号为 446-86-6。Azathioprine是一种免疫抑制剂。
T13032	Sulfamonomethoxine-d4	Others	Others
	Sulfamonomethoxine D4 is a deuterium labeled Sulfamonomethoxine. Sulfamonomethoxine is an agent of long acting sulfonamide antibacterial, used in blood kinetic studies,and blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate.
TMIJ-0204	Betamethasone-d10 Dipropionate
	Betamethasone-d10 Dipropionate 是 Betamethasone Dipropionate 的氘代化合物。Betamethasone Dipropionate 的 CAS 号为 5593-20-4。Betamethasone dipropionate 是糖皮质激素类固醇，具有免疫抑制、抗炎作用。
TMIJ-0383	D-arabinose-13C5
	D-arabinose-13C5 是 D-arabinose 的 13C 的标记化合物。D-arabinose 的 CAS 号为 10323-20-3。D-arabinose 是内源性代谢产物的一种。
TMIJ-0006	Levulinic-d5 Acid
	Levulinic-d5 Acid 是 Levulinic Acid 的氘代化合物。Levulinic Acid 的 CAS 号为 123-76-2。Levulinic acid 是一种合成生物燃料的前体。
TMIJ-0111	Azithromycin-13C-d3
	Azithromycin-13C-d3 是 Azithromycin 的 13C 和氘代化合物。Azithromycin 的 CAS 号为 83905-01-5。Azithromycin是一种常用于细菌感染研究的大环内酯抗生素。
TMID-0242	Capecitabine-d11
	Capecitabine-d11 是 Capecitabine 的氘代化合物。Capecitabine 的 CAS 号为 154361-50-9。Capecitabine 是一种可口服的前药，可由胸苷磷酸化酶催化转变为其活性代谢物 Fluorouracil。
TMID-0227	Rifabutin-d7
	Rifabutin-d7 是 Rifabutin 的氘代化合物。Rifabutin 的 CAS 号为 72559-06-9。Rifabutin是半合成的安莎霉素抗生素，抑制 DNA 依赖性 RNA 聚合酶，有抗分枝杆菌作用。
TMIJ-0011	Chloramphenicol-d5
	Chloramphenicol-d5 是 Chloramphenicol 的氘代化合物。Chloramphenicol 的 CAS 号为 56-75-7。Chloramphenicol 是一种广谱抗生素，有效抑制细菌蛋白质生物合成。它主要作用于细菌 70S 核糖体的 50S 亚基，对肽基转移酶有活性，抑制肽键的形成。
TMIH-0281	Indobufen-d5
	Indobufen-d5 是 Indobufen 的氘代化合物。Indobufen 的 CAS 号为 63610-08-2。Indobufen 是一种血小板聚集抑制剂，是下调单核细胞中的组织因子，可逆抑制血小板环氧合酶 (Cox) 的活性和血栓素 A2 (TxA2) 的合成。
TMIJ-0506	Bis(2-ethylhexyl) Phthalate-d4
	Bis(2-ethylhexyl) Phthalate-d4 是 Bis(2-ethylhexyl) Phthalate 的氘代化合物。Bis(2-ethylhexyl) Phthalate 的 CAS 号为 117-81-7。Bis(2-ethylhexyl) phthalate 是内源性代谢产物的一种。
TMIJ-0214	Itraconazole-d5
	Itraconazole-d5 是 Itraconazole 的氘代化合物。Itraconazole 的 CAS 号为 84625-61-6。Itraconazole是三唑类抗真菌药，也是口服活性的Hedgehog信号通路拮抗剂，IC50约为 800 nM。它也是 oxysterol-binding protein抑制剂。它抑制羊毛甾醇 14α-脱甲基酶，从而抑制羊毛甾醇向麦角固醇的氧化转化。它有抗癌和抗血管作用。
TMIJ-0181	Clindamycin-13C-d3
	Clindamycin-13C-d3 是 Clindamycin 的 13C 和氘代化合物。Clindamycin 的 CAS 号为 18323-44-9。Clindamycin 从细菌核糖体中解离肽基-tRNA，破坏细菌蛋白质合成。它是一种半合成广谱抗生素，由母体化合物林可霉素化学修饰而成。
TMID-0065	Adenine-2-d1
	Adenine-2-d1 是 Adenine 的氘代化合物。Adenine 的 CAS 号为 73-24-5。Adenine 是一种嘌呤衍生物，是一种核碱基。它在细胞呼吸、以富含能量的 ATP 和 NAD 和 FAD 的形式和蛋白质合成作用，作为 DNA 和 RNA 的化学成分。
TMIH-0290	Ketorolac-d5-P1
	Ketorolac-d5-P1 是 Ketorolac 的氘代化合物。Ketorolac 的 CAS 号为 74103-06-3。Ketorolac 是非甾体抗炎剂，是非选择性的COX抑制剂，对 COX-1 和 COX-2 的IC50值分别为 20 和 120 nM。
TMIH-0291	Ketorolac-d5-P2
	Ketorolac-d5-P2 是 Ketorolac 的氘代化合物。Ketorolac 的 CAS 号为 74103-06-3。Ketorolac 是非甾体抗炎剂，是非选择性的COX抑制剂，对 COX-1 和 COX-2 的IC50值分别为 20 和 120 nM。
TMIJ-0103	Suplatast Tosylate-d5
	Suplatast Tosylate-d5 是 Suplatast Tosylate 的氘代化合物。Suplatast Tosylate 的 CAS 号为 94055-76-2。Suplatast Tosilate 是一种口服有活性的 Th2 细胞因子抑制剂，能够阻碍 Th2 细胞产生 IL-4 和 IL-5 ，并对 IgE 的合成具有抑制作用。它是一种抗过敏剂，它具有抗纤维化、抗哮喘及抗炎特性。
TMID-0152	Pyridoxine-d2 HCl
	Pyridoxine-d2 HCl 是 Pyridoxine HCl 的氘代化合物。Pyridoxine HCl 的 CAS 号为 58-56-0。Pyridoxine hydrochloride 是一种吡啶衍生物。在于阿尔茨海默病细胞模型中，通过Nrf-2/HO-1 途径发挥抗氧化作用。
TMIJ-0119	Pitavastatin-d4 Sodium Salt
	Pitavastatin-d4 Sodium Salt 是 Pitavastatin Sodium Salt 的氘代化合物。Pitavastatin Sodium Salt 的 CAS 号为 574705-92-3。
TMID-0286	Rifaximin-d6
	Rifaximin-d6 是 Rifaximin 的氘代化合物。Rifaximin 的 CAS 号为 80621-81-4。Rifaximin是一种胃肠道选择性抗生素，与细菌 DNA 依赖性 RNA 聚合酶的 β 亚基结合，抑制细菌 RNA 合成。与革兰氏阴性菌（MIC：8-50 毫克/毫升）相比，它对革兰氏阳性菌株（MIC：0.03-5 毫克/毫升）的敏感性更高。
TMID-0091	BISPHENOL A-d16
	BISPHENOL A-d16 是 BISPHENOL-A 的氘代化合物。BISPHENOL-A 的 CAS 号为 80-05-7。Bisphenol A 是酚类有机合成化合物，广泛用于环氧树脂和聚碳酸酯塑料的生产。它是生殖、发育和全身毒性物质，常被归类为内分泌干扰物。它与许多疾病有关，包括呼吸系统疾病、心血管疾病、糖尿病、肾脏疾病、肥胖和生殖障碍。
TMIJ-0377	Thiamine Hydrochloride-13C4
	Thiamine Hydrochloride-13C4 是 Thiamine Hydrochloride 的 13C 的标记化合物。Thiamine Hydrochloride 的 CAS 号为 67-03-8。Thiamine hydrochloride 是一种必需的微量营养素，是许多中枢代谢酶的辅因子。
TMIJ-0114	Vardenafil-d5
	Vardenafil-d5 是 Vardenafil 的氘代化合物。Vardenafil 的 CAS 号为 224785-90-4。Vardenafil 是选择性、高效的、具有口服活性的磷酸二酯酶5抑制剂，IC50=0.7 nM。它能够非竞争性地抑制环磷酸鸟苷水解，从而提高 cGMP 水平。它对 PDE1 (180 nM)，PDE6 (11 nM)，PDE2，PDE3，PDE4 (>1000 nM) 具有选择性。它可用于研究勃起功能障碍。
TMID-0092	BISPHENOL-A-3,3',5,5'-d4
	BISPHENOL-A-3,3',5,5'-d4 是 BISPHENOL-A 的氘代化合物。BISPHENOL-A 的 CAS 号为 80-05-7。Bisphenol A 是酚类有机合成化合物，广泛用于环氧树脂和聚碳酸酯塑料的生产。它是生殖、发育和全身毒性物质，常被归类为内分泌干扰物。它与许多疾病有关，包括呼吸系统疾病、心血管疾病、糖尿病、肾脏疾病、肥胖和生殖障碍。
TMID-0093	BISPHENOL-A-2,2',6,6'-d4
	BISPHENOL-A-2,2',6,6'-d4 是 BISPHENOL-A 的氘代化合物。BISPHENOL-A 的 CAS 号为 80-05-7。Bisphenol A 是酚类有机合成化合物，广泛用于环氧树脂和聚碳酸酯塑料的生产。它是生殖、发育和全身毒性物质，常被归类为内分泌干扰物。它与许多疾病有关，包括呼吸系统疾病、心血管疾病、糖尿病、肾脏疾病、肥胖和生殖障碍。
TMIJ-0374	L-Leucine-d3
	L-Leucine-d3 是 L-Leucine 的氘代化合物。L-Leucine 的 CAS 号为 61-90-5。L-Leucine 是必需的支链氨基酸，能够激活mTOR信号通路。
TMIJ-0081	L-Leucine-d10
	L-Leucine-d10 是 L-Leucine 的氘代化合物。L-Leucine 的 CAS 号为 61-90-5。L-Leucine 是必需的支链氨基酸，能够激活mTOR信号通路。
TMID-0090	BISPHENOL-A-2,2',3,3',5,5',6,6'-d8
	BISPHENOL-A-2,2',3,3',5,5',6,6'-d8 是 BISPHENOL-A 的氘代化合物。BISPHENOL-A 的 CAS 号为 80-05-7。Bisphenol A 是酚类有机合成化合物，广泛用于环氧树脂和聚碳酸酯塑料的生产。它是生殖、发育和全身毒性物质，常被归类为内分泌干扰物。它与许多疾病有关，包括呼吸系统疾病、心血管疾病、糖尿病、肾脏疾病、肥胖和生殖障碍。
T71401	Oxaliplatin-d10
	Oxaliplatin-d10 is intended for use as an internal standard for the quantification of oxaliplatin by GC- or LC-MS. Oxaliplatin is a platinum-containing DNA-crosslinking agent. It induces the formation of DNA inter- and intrastrand crosslinks and DNA-protein adducts, inhibits DNA and RNA synthesis, and induces apoptosis in cancer cells. Oxaliplatin is cytotoxic to cisplatin-sensitive A2780(1A9) and KB-3-1 cells and cisplatin-resistant A2780-E(80) and KB-CP20 cells (IC50s = 0.12, 0.39, 4.7, and 2....
T35517	4-deoxy Nivalenol-13C15 4-deoxy Nivalenol-13C15
	4-deoxy Nivalenol-13C15is intended for use as an internal standard for the quantification of 4-deoxy nivalenol by GC- or LC-MS. 4-deoxy Nivalenol is a trichothecene mycotoxin that has been found inFusarium.1It binds to eukaryotic ribosomes and inhibits protein synthesis in mice when administered at doses ranging from 5 to 25 mg/kg. 4-deoxy Nivalenol (0.1 and 0.2 mg/kg) induces emesis in pigs and decreases feed consumption in pigs when administered at a dose of 40 ppb in the diet.2It induces leth...
T69395	Nicotinamide-d4
	Nicotinamide-d4 is intended for use as an internal standard for the quantification of nicotinamide by GC- or LC-MS. Nicotinamide is an amide form of niacin, which is also known as vitamin B3, that can be biosynthesized in vivo or obtained through the diet. It is a precursor in the synthesis of the metabolic cofactor NAD+ and an inhibitor of sirtuin 1 (SIRT1; IC50 = <50 µM). Nicotinamide (10 µM) increases the activity of serine palmitoyltransferase (SPT) and the biosynthesis of ceramide, glucosyl...
TMID-0078	Irinotecan-d10 Hydrochloride
	Irinotecan-d10 Hydrochloride 是 Irinotecan Hydrochloride 的氘代化合物。Irinotecan Hydrochloride 的 CAS 号为 100286-90-6。Irinotecan Hydrochloride 是喜树碱半合成衍生物的盐酸盐，是一种拓扑异构酶 I 抑制剂，可研究结肠癌和直肠癌。
TMIJ-0384	L-Cysteine-d3
	L-Cysteine-d3 是 L-Cysteine 的氘代化合物。L-Cysteine 的 CAS 号为 52-90-4。L-Cysteine 是人体非必需的含硫氨基酸。L-Cysteine 对蛋白质合成、解毒和多种代谢功能很重要。L-Cysteine 存在于指甲、皮肤和头发的主要蛋白质-角蛋白中，对胶原蛋白的生成、皮肤弹性和质地都很重要。L-Cysteine 是抗氧化剂谷胱甘肽的一种成分，在辅酶A、肝素和生物素等基本生化物质的代谢中起着重要作用，也是氨基酸牛磺酸的制造所必需的。
T35775	HT-2 Toxin-13C22 HT-2 Toxin-13C22
	HT-2 toxin-13C22is intended for use as an internal standard for the quantification of HT-2 toxin by GC- or LC-MS. HT-2 toxin is a type A trichothecene mycotoxin and an active, deacetylated metabolite of the trichothecene mycotoxin T-2 toxin .1,2Like T-2 toxin, HT-2 toxin inhibits protein synthesis and cell proliferation in plants.2HT-2 toxin also reduces viability of HepG2, A549, HEp-2, Caco-2, A-204, U937, Jurkat, and RPMI-8226 cancer cells with IC50values ranging from 3.1 to 23 ng/ml and human...
T36383	L-Thyroxine-13C9,15N L-Thyroxine-13C9,15N
	L-Thyroxine-13C9,15N is intended for use as an internal standard for the quantification of L-thyroxine by GC- or LC-MS. L-Thyroxine is a synthetic form of the thyroid hormone thyroxine. In vivo, L-thyroxine (0.9 and 2.7 μg) inhibits synthesis and release of thyrotropin induced by thyrotropin-releasing hormone from the anterior pituitary in mice. It also reverses decreases in levels of circulating thymic serum factor (FTS) and the number of T rosette-forming cells in an old age-induced mouse mode...

同位素标记化合物

Cat.No: T38035

Synonym: Phenol-13C6

Cat.No: T10992

Synonym: OPC-67683 D4

Target: Others

Cat.No: T11853

Synonym: Linezolid D3,PNU-100766 D3

Target: Others

Sulfamerazine D4

Cat.No: T13028

Target: Others

5-Fluorouracil-13C,15N2

Cat.No: T36895

Synonym: 5-Fluorouracil-13C,15N2

L-Arginine-15N4 hydrochloride

Cat.No: T39441

Synonym: L-Arginine-15N4 hydrochloride,(S)-(+)-Arginine-15N4 hydrochloride

Proguanil-d6 HCl

Cat.No: TMIH-0457

Azathioprine-d3

Cat.No: TMID-0087

Sulfamonomethoxine-d4

Cat.No: T13032

Target: Others

Betamethasone-d10 Dipropionate

Cat.No: TMIJ-0204

D-arabinose-13C5

Cat.No: TMIJ-0383

Levulinic-d5 Acid

Cat.No: TMIJ-0006

Azithromycin-13C-d3

Cat.No: TMIJ-0111

Capecitabine-d11

Cat.No: TMID-0242

Cat.No: TMID-0227

Chloramphenicol-d5

Cat.No: TMIJ-0011

Cat.No: TMIH-0281

Bis(2-ethylhexyl) Phthalate-d4

Cat.No: TMIJ-0506

Itraconazole-d5

Cat.No: TMIJ-0214

Clindamycin-13C-d3

Cat.No: TMIJ-0181

Cat.No: TMID-0065

Ketorolac-d5-P1

Cat.No: TMIH-0290

Ketorolac-d5-P2

Cat.No: TMIH-0291

Suplatast Tosylate-d5

Cat.No: TMIJ-0103

Pyridoxine-d2 HCl

Cat.No: TMID-0152

Pitavastatin-d4 Sodium Salt

Cat.No: TMIJ-0119

Cat.No: TMID-0286

BISPHENOL A-d16

Cat.No: TMID-0091

Thiamine Hydrochloride-13C4

Cat.No: TMIJ-0377

Cat.No: TMIJ-0114

BISPHENOL-A-3,3',5,5'-d4

Cat.No: TMID-0092

BISPHENOL-A-2,2',6,6'-d4

Cat.No: TMID-0093

Cat.No: TMIJ-0374

Cat.No: TMIJ-0081

BISPHENOL-A-2,2',3,3',5,5',6,6'-d8

Cat.No: TMID-0090

Oxaliplatin-d10

Cat.No: T71401

4-deoxy Nivalenol-13C15

Cat.No: T35517

Synonym: 4-deoxy Nivalenol-13C15

Nicotinamide-d4

Cat.No: T69395

Irinotecan-d10 Hydrochloride

Cat.No: TMID-0078

Cat.No: TMIJ-0384

HT-2 Toxin-13C22

Cat.No: T35775

Synonym: HT-2 Toxin-13C22

L-Thyroxine-13C9,15N

Cat.No: T36383

Synonym: L-Thyroxine-13C9,15N

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