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Diethylene Glycol Monobenzyl Ether is a PEG-based linker, specifically designed for the synthesis of PROTACs[1]. It serves as a versatile chemical compound, enabling the formation of PROTAC molecules by connecting target protein ligands with E3 ligase ligands, ultimately leading to targeted protein degradation.
Diethylene Glycol Monobenzyl Ether is a PEG-based linker, specifically designed for the synthesis of PROTACs[1]. It serves as a versatile chemical compound, enabling the formation of PROTAC molecules by connecting target protein ligands with E3 ligase ligands, ultimately leading to targeted protein degradation.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 g | ¥ 913 | 5日内发货 |
产品描述 | Diethylene Glycol Monobenzyl Ether is a PEG-based linker, specifically designed for the synthesis of PROTACs[1]. It serves as a versatile chemical compound, enabling the formation of PROTAC molecules by connecting target protein ligands with E3 ligase ligands, ultimately leading to targeted protein degradation. |
体外活性 | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
分子量 | 196.24 |
分子式 | C11H16O3 |
CAS No. | 2050-25-1 |
密度 | 1.094 g/cm3 at 25℃ (lit.) |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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