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Dithranol (cignoline) 是蒽醌衍生物,可破坏线粒体功能和结构,用于治疗皮肤病。
Dithranol (cignoline) 是蒽醌衍生物,可破坏线粒体功能和结构,用于治疗皮肤病。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 mg | ¥ 184 | 现货 | |
100 mg | ¥ 333 | 现货 | |
500 mg | ¥ 715 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 227 | 现货 |
产品描述 | Dithranol (cignoline) is an anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especially PSORIASIS. It may cause FOLLICULITIS. |
激酶实验 | THP-1 and HEK293 cells are transiently transfected using DEAE-dextran and Polyfect reagent, respectively. Plasmids transfected contain genes coding for the NF-κB-dependent pELAM-luc luciferase reporter, TLR2, TLR4, CD14, and MD2. Cells (5×105 THP-1 or 1×105 HEK293) are added to 12-well plates, washed after 18 h, and stimulated for 5 h. Cells are then lysed with reporter lysis buffer as directed, and lysates are analyzed for luminescence using Promega luciferase substrate and a Monolight 3010 luminometer. |
别名 | 1,8,9-trihydroxyanthracene, cignoline, Anthralin, 蒽林 |
分子量 | 226.23 |
分子式 | C14H10O3 |
CAS No. | 1143-38-0 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
溶解度信息 | Chloroform: 41 mg/mL DMSO: 10 mM | ||||||||||||||||||||
溶液配制表 | |||||||||||||||||||||
DMSO
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