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Fmoc-L-Lys(4-N3-Z)-OH 是一种具备叠氮基功能的化学试剂,并作为SPPS中的赖氨酸构建块,用于生物正交连接、红外探针及光亲和试剂.此化合物通过细菌诱导的1,3-偶极环加成反应,可以进行反式环辛烯醇脱羧.作为点击化学工具,Fmoc-L-Lys(4-N3-Z)-OH 含有Azide基团,能与含Alkyne基团的分子通过铜催化的叠氮-炔环加成反应(CuAAc)产生作用,亦可与含DBCO或BCN基团的分子进行细菌诱导的炔-叠氮环加成反应(SPAAC).
Fmoc-L-Lys(4-N3-Z)-OH 是一种具备叠氮基功能的化学试剂,并作为SPPS中的赖氨酸构建块,用于生物正交连接、红外探针及光亲和试剂.此化合物通过细菌诱导的1,3-偶极环加成反应,可以进行反式环辛烯醇脱羧.作为点击化学工具,Fmoc-L-Lys(4-N3-Z)-OH 含有Azide基团,能与含Alkyne基团的分子通过铜催化的叠氮-炔环加成反应(CuAAc)产生作用,亦可与含DBCO或BCN基团的分子进行细菌诱导的炔-叠氮环加成反应(SPAAC).
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 10-14周 | |
50 mg | 询价 | 10-14周 |
产品描述 | Fmoc-L-Lys(4-N3-Z)-OH is a chemical reagent characterized by its azide group. This compound serves as a lysine building block in solid-phase peptide synthesis (SPPS) with azide functionality, useful as a bioorthogonal handle, an infrared probe, and a photoaffinity label. It undergoes strain-promoted 1,3-dipolar cycloaddition facilitated by trans-cyclooctene decarboxylation. Additionally, Fmoc-L-Lys(4-N3-Z)-OH functions as a click chemistry reagent, enabling copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing alkyne groups. Moreover, it can participate in strain-promoted alkyne-azide cycloaddition reactions (SPAAC) with molecules that possess DBCO or BCN groups. |
分子量 | 543.57 |
分子式 | C29H29N5O6 |
CAS No. | 1446511-14-3 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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