Oxacillin

Name: Oxacillin
Brand: TargetMol
SKU: T61951
Price: -1 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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产品编号 T61951Cas号 66-79-5

Oxacillin 是口服有效的合成青霉素。Oxacillin 对葡萄球菌和其他革兰氏阳性病原体具有良好的杀菌 (bactericidal) 活性。

还可以

产品编号 T61951Cas号 66-79-5

Oxacillin 是口服有效的合成青霉素。Oxacillin 对葡萄球菌和其他革兰氏阳性病原体具有良好的杀菌 (bactericidal) 活性。

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产品介绍

生物活性

产品描述	Oxacillin is an orally active synthetic penicillin. Oxacillin shows good bactericidal activity against staphylococci and other gram-positive pathogens.
体外活性	Oxacillin inhibits gram positive pathogens with MICs of 0.05, 0.09, 0.32 and 0.80 μg/mL against group A streptococci, Pneutnococci, susceptible staphylococci and penicillin-resistant staphylococci, respectively [1]. The Oxacillin-resistant strains are highly resistant to other penicillins [1].
体内活性	Oxacillin (50-800 mg/kg; s.c.; once) shows curative dose (CD 50 ) of 253.3 mg/kg in mice infected with Staphylococcus aureus Evans. The oral CD 50 of Oxacillin is 187.2 mg/kg [2]. Animal Model: CD-1 strain male albino mice infected with S. aureus Evans [2] Dosage: 50, 100, 200, 400 and 800 mg/kg Administration: Subcutaneous injection, once Result: Showed therapeutic activity with CD 50 of 253.3 mg/kg.