Name: β-Amanitin
Brand: TargetMol
SKU: T13474
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

1 mg

¥ 9,730

35日内发货

生物活性

产品描述	β-Amanitin, a cyclic peptide toxin found in the poisonous Amanita phalloides mushroom, inhibits eukaryotic RNA polymerase II and III, thereby disrupting protein synthesis.
体外活性	In MCF-7 cells, β-Amanitin (0.01-100 μg/mL; 36 hours) shows toxicity, and the rates of cell viability are calculated as 52%, 62%, 84%, 86%, and 91% at concentrations of 100, 10, 1, 0.1, and 0.01 μg/mL, respectively[2].In MCF-7 cells, β-Amanitin shows a great inhibition of protein synthesis at both concentrations (10 μg/mL and 1 μg/mL) for 24 hours[2].
别名	β-鹅膏菌素

化学信息

分子量	919.96
分子式	C₃₉H₅₃N₉O₁₅S
CAS No.	21150-22-1
Smiles	[H][C@@]12C[C@@H](O)CN1C(=O)[C@]([H])(CC(O)=O)NC(=O)[C@]1([H])C[S@](=O)c3[nH]c4cc(O)ccc4c3C[C@]([H])(NC(=O)[C@@]([H])(NC2=O)[C@@H](C)[C@@H](O)CO)C(=O)NCC(=O)N[C@@]([H])([C@@H](C)CC)C(=O)NCC(=O)N1
密度	1.1725 g/cm3 (Estimated)