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Search Results for " tyrosine "
Targets Recommended: Tyrosine Kinases Others

800

抑制剂 & 化合物

84

天然产物

2

化合物库

460

重组蛋白

30

同位素标记化合物

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Cat. No. Product Name
L2200 酪氨酸激酶分子库

1016 compounds
1016 种酪氨酸激酶抑制剂的独特集合,可用于高通量筛选和高内涵筛选;
L9410 共价抑制剂库

1920 compounds
1920 种小分子的独特集合,包含已发现的共价抑制剂以及包含某些共价反应基团常见弹头的分子,如氯乙酰基,2-氯丙酰基,丙烯酰基,1-丙-2-炔基,1-丁-2-炔基,酮羰基,二硫键等,可以用于共价抑制剂药物研发;

化合物库

酪氨酸激酶分子库
Cat.No: L2200
Compounds: 1016
共价抑制剂库
Cat.No: L9410
Compounds: 1920
Cat. No. Product Name Target Signaling Pathways
T19922 L-m-Tyrosine

L(-)mTyrosine,3-羟基-L-苯基丙氨酸,L (-) m Tyrosine,LmTyrosine,3-Hydroxy-L-Phenylalanine,L-(-)-m-Tyrosine

Others Others
L-m-Tyrosine (3-Hydroxy-L-Phenylalanine) 是一种非天然氨基酸。L-m-Tyrosine 在治疗帕金森病、关节炎和阿尔茨海默病方面显示出潜力。
T60108 PDGFR Tyrosine Kinase Inhibitor III

PDGF Receptor Tyrosine Kinase Inhibitor III

PDGFR Angiogenesis; Tyrosine Kinase/Adaptors
PDGFR Tyrosine Kinase Inhibitor III (PDGF Receptor Tyrosine Kinase Inhibitor III) (PDGF Receptor Tyrosine Kinase Inhibitor III)是一种多激酶抑制剂,可抑制 PDGFR、EGFR、FGFR、PKA 和 PKC 等。PDGFR Tyrosine Kinase Inhibitor III 可用于肌萎缩侧索硬化症的研究。
T5466 Tyrosine kinase-IN-1

VEGFR; FGFR; FLT; PDGFR Angiogenesis; Tyrosine Kinase/Adaptors
Tyrosine kinase-IN-1是一种多靶点酪氨酸激酶抑制剂,能够抑制KDR (IC50:4 nM),Flt-1 (IC50:20 nM),FGFR1 (IC50:4 nM) 和 PDGFRα (IC50:2 nM)。
T9492 3-METHOXY-DL-TYROSINE

Others Others
3-METHOXY-DL-TYROSINE 是一种在人体和许多其他生物体中发现的天然氨基酸,是一种非必需氨基酸。它是神经递质多巴胺的前体,参与大脑中多巴胺水平的调节,在多种疾病中有潜在治疗应用,包括帕金森病、抑郁症和肥胖症。
T77746 Tyrosine kinase-IN-7

EGFR; Antiviral Angiogenesis; Immunology/Inflammation; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Tyrosine kinase-IN-7 是一种有效的酪氨酸激酶 EGFR 抑制剂,抑制 EGFR(WT) 和 EGFR(T790M) ,在多种癌细胞系中显示出抗癌和抗肿瘤活性。Tyrosine kinase-IN-7 具有潜在的抗炎和抗病毒活性。
T34713 Stearyl tyrosine

Stearyl-tyrosine,Stearyltyrosine

Others Others
Stearyl tyrosine is an immunoadjuvants, long-chain stearyl ester of amino acids and peptides.
T41208 NB-caged Tyrosine hydrochloride

ONBY,NB-caged Tyrosine hydrochloride

Others Others
NB-caged Tyrosine hydrochloride is a L-Tyrosine caged with photosensitiveortho-nitrobenzyl side chain. Rapidly releases tyrosine when photolyzed (300-350 nm excitation). Is readily incorporated intoE.coliproteins via inclusion in growth media.
T38222 N-(α-Linolenoyl) Tyrosine

Certain chronic neurologic disorders, such as Parkinson's disease, are caused by an insufficiency of the neurotransmitter dopamine secondary to the degeneration of substantia nigra dopaminergic neurons. N-(α-Linolenoyl) tyrosine (NALT) is a simple α-amide conjugate between the ω-3 essential fatty acid α-linolenate and the amino acid tyrosine. α-Linolenate is an important precursor to docosahexaenoic acid (DHA), a prominent brain polyunsaturated fatty acid, while tyrosine is the metabolic precurs...
T17184 Tyrosine kinase inhibitor

c-Met/HGFR; Tyrosine Kinases Tyrosine Kinase/Adaptors
Tyrosine kinase inhibitor 是酪氨酸激酶的有效抑制剂。
T39178 Tyrosine Kinase Peptide 1

Tyrosine Kinase Peptide 1 is a control substrate peptide for c-Src assay.
T33169 Malyl tyrosine

Others Others
Malyl tyrosine is a derivative of amino-acid.
T40846 3,5-Difluoro-L-tyrosine

Others Others
3,5-Difluoro-L-tyrosine is a functional and tyrosinase-resistant mimic of tyrosine, commonly utilized for evaluating the substrate specificity of protein tyrosine phosphatases (PTPs).
T40408 N-Pivaloyl-L-tyrosine

Others Others
N-Pivaloyl-L-tyrosine is an N-pivaloyl amino acid ester.
T4344 ALW-II-41-27

Eph receptor tyrosine kinase inhibitor

Ephrin Receptor Tyrosine Kinase/Adaptors
ALW-II-41-27 (Eph receptor tyrosine kinase inhibitor) 是一种 Eph 受体酪氨酸激酶抑制剂,可用于治疗癌症。
T41099 EGFR Protein Tyrosine Kinase Substrate

EGFR Protein Tyrosine Kinase Substrate is a EGFR protein tyrosine kinase substrate.
T32675 Leucyl-leucyl-tyrosine

L-Leu-L-leu-L-tyr

Others Others
Leucyl-leucyl-tyrosine is a bioactive chemical.
TP1269 Tyrosine Protein Kinase JAK 2 (Phospho-Tyr8, 9)

Tyrosine Protein Kinase JAK2 Phospho-Tyr8, 9

Tyrosine Protein Kinase JAK 2 (Phospho-Tyr8, 9) is a peptide derived from mouse JAK2, specifically composed of amino acids 475 to 491.
T73614 Tyrosine decarboxylase

Others Others
Tyrosine decarboxylase (TDC; TyrDC),即酪氨酸脱羧酶,广泛存在于植物、昆虫和不同微生物中,常用于生化研究。Tyrosine decarboxylase 是一种5'-磷酸吡哆醛 (PLP) 依赖性脱羧酶,可以催化酪氨酸中羧基的去除,产生酪胺和二氧化碳。
T61730 Tyrosine kinase-IN-4

Others Others
Tyrosine kinase-IN-4 (EXAMPLE 107) 是一种酪氨酸激酶 (tyrosine kinase) 抑制剂。
T79612 Tyrosine kinase-IN-6

c-Met/HGFR Tyrosine Kinase/Adaptors
Tyrosine kinase-IN-6为RON剪接变异体抑制剂,有效展现抗癌及抗肿瘤活性。
T20556 Tyrosyltyrosine

Tyr-tyr,Peptide tyrosine-tyrosine,Tyrosyl tyrosine

Others Others
Tyrosyltyrosine is a dipeptide.
T35631 Peptide YY (human) (trifluoroacetate salt)

Peptide Tyrosine Tyrosine

Peptide YY (PYY) is a 36-amino acid peptide and anorectic gut hormone agonist for the neuropeptide Y receptors Y1, Y2, Y5, and Y6 with EC50 values of 0.7, 0.58, 1, and 0.8 nM, respectively, for supression of forskolin-induced cAMP accumulation. PYY is cleaved in vivo to PYY (3-36) . Release of PYY occurs postprandially in proportion to calorie intake from intestinal enteroendocrine L cells, indicating it may be a satiety signal. In humans, PYY inhibits food intake and gastrointestinal transit in...
T67308 3-Fluoro-L-tyrosine

Others Others
3-Fluoro-L-tyrosine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T67308。
T126438 L-Tyrosine, methyl ester

Others Others
L-Tyrosine, methyl ester 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T126438,CAS号为 1080-06-4。
T65730 N-Fmoc-3-nitro-L-tyrosine

Others Others
N-Fmoc-3-nitro-L-tyrosine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65730,CAS号为 136590-09-5。
T21761 HNMPA

IGF-1R Tyrosine Kinase/Adaptors
HNMPA 是膜不可渗透的胰岛素受体酪氨酸激酶 (insulin receptor tyrosine kinase) 抑制剂。HNMPA 可以抑制人胰岛素受体的酪氨酸和丝氨酸自磷酸化。HNMPA 对环 AMP 依赖性蛋白激酶或蛋白激酶 C 活性没有影响。
T124433 3-Nitro-L-tyrosine ethyl ester hydrochloride

Others Others
3-Nitro-L-tyrosine ethyl ester hydrochloride 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124433。
T65630 N-Benzoyl-L-tyrosine ethyl ester

N-Benzoyl-L-tyrosine ethyl ester 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65630,CAS号为 3483-82-7。
T77237 N,O-Didansyl-L-tyrosine cyclohexylammonium

N,O-Didansyl-L-tyrosine cyclohexylammonium 是一种有效的选择性胸苷酸合成酶 (TS) 抑制剂,作用于Escherichia coli,Lactobacillus casei 和人的 TS 的IC50值分别是 5.0,3.4 和 119 μM。
T20698 Leucyltyrosine

L-Leucyl-L-tyrosine

Others Others
Leucyltyrosine is a dipeptide.
T20554 N-Benzoyltyrosine

N-Benzoyl-L-tyrosine

Others Others
N-benzoyl tyrosine is a dipeptide.
T8848 GPR34 receptor antagonist 2

Tyrosine, N-[(2E)-3-(4'-chloro[1,1'-biphenyl]-4-yl)-1-oxo-2-propen-1-yl]-O-(phenylmethyl)-,gpr34-receptor-antagonist-2

Others Others
GPR34 receptor antagonist 2 (Tyrosine, N-[(2E)-3-(4'-chloro[1,1'-biphenyl]-4-yl)-1-oxo-2-propen-1-yl]-O-(phenylmethyl)-) 是一种GPR34受体拮抗剂,可用于研究免疫疾病、炎性疾病。
T23504 VEGFR-IN-1

VEGFR Tyrosine Kinase Inhibitor II

Others Others
VEGFR inhibitor
T2431 ID-8

ID8

DYRK Cell Cycle/Checkpoint; Tyrosine Kinase/Adaptors
ID-8 是 DYRK 抑制剂,长时间培养能够维持胚胎干细胞的自我更新。
T31162 Cysteinyltyrosine

N-L-Cysteinyl-L-tyrosine,Cys-tyr

Others Others
Cysteinyltyrosine is a dipeptide composed of cysteine and tyrosine. It is an incomplete breakdown product of protein digestion or protein catabolism.
T16730 Remibrutinib

BTK Angiogenesis; Tyrosine Kinase/Adaptors
Remibrutinib 是有效的、口服具有活力的 bruton tyrosine kinase 抑制剂 (IC50:1 nM),在血液中抑制 BTK 活性的 IC50的值为 0.23 μM。它具有研究慢性荨麻疹的潜力。
T20700 Racemetirosine

Others Others
Racemetirosine 是一种酪氨酸 3-单加氧酶抑制剂,因此会抑制儿茶酚胺的合成。
T6257 AZ191

DYRK Cell Cycle/Checkpoint; Tyrosine Kinase/Adaptors
AZ191 是特异性 DYRK1B 抑制剂。它对 DYRK1B 的特异性分别是 DYRK1A 和 DYRK2 的 5 倍和 110 倍。
T15422 GSK-626616

DYRK Cell Cycle/Checkpoint; Tyrosine Kinase/Adaptors
GSK-626616 是一种口服具有活力的 DYRK3抑制剂 (IC50:0.7 nM)。它以相似的效力抑制 DYRK 家族的其他成员,可用于研究贫血。
TQ0111 LDN-192960

DYRK; Haspin Kinase Cell Cycle/Checkpoint; Tyrosine Kinase/Adaptors
LDN-192960 是 Haspin 和 DYRK2 的有效抑制剂(IC50:10 nM 和 48 nM)。
T2314 PF-431396

FAK; PYK2 Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
PF 431396 是一种具有口服活性的 FAK (IC50:2 nM) 和 Pyk2 (IC50:11 nM)的抑制剂。
T4209 TAK-659 hydrochloride

TAK-659

VEGFR; FLT; Tyrosine Kinases; JAK; Syk Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
TAK-659 hydrochloride (TAK-659) 是可逆的、高效的、选择性的、口服有效的 SYK/FLT3 双抑制剂,对 SYK 和 FLT3 作用的IC50值分别为 3.2 nM、4.6 nM。它能诱导肿瘤细胞死亡,却不作用于非肿瘤细胞,对慢性淋巴细胞白血病具有潜在的研究价值。
T30906 Cholylglycyltyrosine

Chol-gly-tyr,125I-Cgtyr,I-Cholylglycyltyrosine,Cholyl-glycyl-tyrosine

Others Others
Cholylglycyltyrosine is a hepatobiliary imaging agent.
T6115 Fostamatinib

R788,福他替尼

FLT; Syk; Monoamine Transporter; Adenosine Receptor Angiogenesis; GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience; Tyrosine Kinase/Adaptors
Fostamatinib (R788) 是一种口服具有活力的 R406 前药。其中R406 是具有口服活性的,有效的,ATP 竞争性的Syk/FLT3抑制剂(Ki:30 nM,IC50:41 nM),也能够抑制 Lyn (IC50:63 nM) 和 Lck (IC50:37 nM)。
T11447 GNF4877

GSK-3; DYRK Cell Cycle/Checkpoint; PI3K/Akt/mTOR signaling; Stem Cells; Tyrosine Kinase/Adaptors
GNF4877 是一种 DYRK1A (IC50:6 nM) 和 GSK3β (IC50:16 nM) 抑制剂。 它导致激活 T 细胞核因子核输出的阻断和 β 细胞增殖细胞增加。
T9125 Tolebrutinib

PRN2246,SAR442168

BTK Angiogenesis; Tyrosine Kinase/Adaptors
Tolebrutinib (PRN2246) 是一种选择性、有效的、具有口服活性、可透过血脑屏障的布鲁顿氏酪氨酸激酶抑制剂,能够作用于 Ramos B 细胞 (IC50:0.4 nM)、HMC 小胶质细胞 (IC50:0.7 nM)。它对中枢神经系统免疫具有功效。它可用于多发性硬化症的研究。
T1976 RN486

BTK Angiogenesis; Tyrosine Kinase/Adaptors
RN486 是选择性的,具有口服活性的Btk 抑制剂 (IC50:4.0 nM;Kd:0.31 nM),对其他激酶的活性较低。它可用于类风湿关节炎和系统性红斑狼疮的研究。
T3626 Acalabrutinib

ACP-196,阿可替尼

BTK Angiogenesis; Tyrosine Kinase/Adaptors
Acalabrutinib (ACP-196) 是一种不可逆的、高效的、具有口服活性、选择性的第二代BTK 抑制剂。它与 BTK 的 ATP 结合口袋中的 Cys481 共价结合。它在慢性淋巴细胞性白血病 (CLL) 小鼠模型中显示出强大的靶向作用和功效。
T5138 BMS-986142

BTK Angiogenesis; Tyrosine Kinase/Adaptors
BMS986142 是一种有效的、具有高选择性的 Bruton's 酪氨酸激酶 (BTK)可逆性抑制剂 (IC50:0.5 nM)。
T14980 CLK-IN-T3

DYRK; CDK Cell Cycle/Checkpoint; Tyrosine Kinase/Adaptors
CLK-IN-T3 是 CLK1、CLK2 和 CLK3 的抑制剂,IC50 为 0.67、15 和 110 nM。 CLK-IN-T3 具有抗癌活性。

化合物

L-m-Tyrosine
Cat.No: T19922
Synonym: L(-)mTyrosine,3-羟基-L-苯基丙氨酸,L (-) m Tyrosine,LmTyrosine,3-Hydroxy-L-Phenylalanine,L-(-)-m-Tyrosine
Target: Others
PDGFR Tyrosine Kinase Inhibitor III
Cat.No: T60108
Synonym: PDGF Receptor Tyrosine Kinase Inhibitor III
Target: PDGFR
Tyrosine kinase-IN-1
Cat.No: T5466
Synonym:
Target: VEGFR, FGFR, FLT, PDGFR
3-METHOXY-DL-TYROSINE
Cat.No: T9492
Synonym:
Target: Others
Tyrosine kinase-IN-7
Cat.No: T77746
Synonym:
Target: EGFR, Antiviral
Stearyl tyrosine
Cat.No: T34713
Synonym: Stearyl-tyrosine,Stearyltyrosine
Target: Others
NB-caged Tyrosine hydrochloride
Cat.No: T41208
Synonym: ONBY,NB-caged Tyrosine hydrochloride
Target: Others
N-(α-Linolenoyl) Tyrosine
Cat.No: T38222
Synonym:
Target:
Tyrosine kinase inhibitor
Cat.No: T17184
Synonym:
Target: c-Met/HGFR, Tyrosine Kinases
Tyrosine Kinase Peptide 1
Cat.No: T39178
Synonym:
Target:
Malyl tyrosine
Cat.No: T33169
Synonym:
Target: Others
3,5-Difluoro-L-tyrosine
Cat.No: T40846
Synonym:
Target: Others
N-Pivaloyl-L-tyrosine
Cat.No: T40408
Synonym:
Target: Others
ALW-II-41-27
Cat.No: T4344
Synonym: Eph receptor tyrosine kinase inhibitor
Target: Ephrin Receptor
EGFR Protein Tyrosine Kinase Substrate
Cat.No: T41099
Synonym:
Target:
Leucyl-leucyl-tyrosine
Cat.No: T32675
Synonym: L-Leu-L-leu-L-tyr
Target: Others
Tyrosine Protein Kinase JAK 2 (Phospho-Tyr8, 9)
Cat.No: TP1269
Synonym: Tyrosine Protein Kinase JAK2 Phospho-Tyr8, 9
Target:
Tyrosine decarboxylase
Cat.No: T73614
Synonym:
Target: Others
Tyrosine kinase-IN-4
Cat.No: T61730
Synonym:
Target: Others
Tyrosine kinase-IN-6
Cat.No: T79612
Synonym:
Target: c-Met/HGFR
Tyrosyltyrosine
Cat.No: T20556
Synonym: Tyr-tyr,Peptide tyrosine-tyrosine,Tyrosyl tyrosine
Target: Others
Peptide YY (human) (trifluoroacetate salt)
Cat.No: T35631
Synonym: Peptide Tyrosine Tyrosine
Target:
3-Fluoro-L-tyrosine
Cat.No: T67308
Synonym:
Target: Others
L-Tyrosine, methyl ester
Cat.No: T126438
Synonym:
Target: Others
N-Fmoc-3-nitro-L-tyrosine
Cat.No: T65730
Synonym:
Target: Others
HNMPA
Cat.No: T21761
Synonym:
Target: IGF-1R
3-Nitro-L-tyrosine ethyl ester hydrochloride
Cat.No: T124433
Synonym:
Target: Others
N-Benzoyl-L-tyrosine ethyl ester
Cat.No: T65630
Synonym:
Target:
N,O-Didansyl-L-tyrosine cyclohexylammonium
Cat.No: T77237
Synonym:
Target:
Leucyltyrosine
Cat.No: T20698
Synonym: L-Leucyl-L-tyrosine
Target: Others
N-Benzoyltyrosine
Cat.No: T20554
Synonym: N-Benzoyl-L-tyrosine
Target: Others
GPR34 receptor antagonist 2
Cat.No: T8848
Synonym: Tyrosine, N-[(2E)-3-(4'-chloro[1,1'-biphenyl]-4-yl)-1-oxo-2-propen-1-yl]-O-(phenylmethyl)-,gpr34-receptor-antagonist-2
Target: Others
VEGFR-IN-1
Cat.No: T23504
Synonym: VEGFR Tyrosine Kinase Inhibitor II
Target: Others
ID-8
Cat.No: T2431
Synonym: ID8
Target: DYRK
Cysteinyltyrosine
Cat.No: T31162
Synonym: N-L-Cysteinyl-L-tyrosine,Cys-tyr
Target: Others
Remibrutinib
Cat.No: T16730
Synonym:
Target: BTK
Racemetirosine
Cat.No: T20700
Synonym:
Target: Others
AZ191
Cat.No: T6257
Synonym:
Target: DYRK
GSK-626616
Cat.No: T15422
Synonym:
Target: DYRK
LDN-192960
Cat.No: TQ0111
Synonym:
Target: DYRK, Haspin Kinase
PF-431396
Cat.No: T2314
Synonym:
Target: FAK, PYK2
TAK-659 hydrochloride
Cat.No: T4209
Synonym: TAK-659
Target: VEGFR, FLT, Tyrosine Kinases, JAK, Syk
Cholylglycyltyrosine
Cat.No: T30906
Synonym: Chol-gly-tyr,125I-Cgtyr,I-Cholylglycyltyrosine,Cholyl-glycyl-tyrosine
Target: Others
Fostamatinib
Cat.No: T6115
Synonym: R788,福他替尼
Target: FLT, Syk, Monoamine Transporter, Adenosine Receptor
GNF4877
Cat.No: T11447
Synonym:
Target: GSK-3, DYRK
Tolebrutinib
Cat.No: T9125
Synonym: PRN2246,SAR442168
Target: BTK
RN486
Cat.No: T1976
Synonym:
Target: BTK
Acalabrutinib
Cat.No: T3626
Synonym: ACP-196,阿可替尼
Target: BTK
BMS-986142
Cat.No: T5138
Synonym:
Target: BTK
CLK-IN-T3
Cat.No: T14980
Synonym:
Target: DYRK, CDK
Cat. No. Product Name Target Signaling Pathways
T0493 L-Tyrosine

Tyrosine,P-Tyrosine,L-酪氨酸,L-p-Tyrosine,(S)-Tyrosine,酪氨酸

Amino Acids and Derivatives; Endogenous Metabolite Metabolism
L-Tyrosine ((S)-Tyrosine) 是一种非必需氨基酸,对后部皮层中柠檬酸合成酶具有抑制活性。
TN1545 D-Tyrosine

Tyrosinase Proteases/Proteasome
D-Tyrosine,是酪氨酸的D异构体,通过抑制酪氨酸酶活性,作为黑色素合成的负向调节剂。此外,D-Tyrosine还能抑制生物膜的形成,并诱导生物膜的自我分散,同时不影响细菌的生长。
TN1596 DL-Tyrosine

Others Others
DL-Tyrosine 是一种由必需氨基酸苯丙氨酸合成的芳香族非必需氨基酸。它是几种重要神经递质(如肾上腺素、去甲肾上腺素、多巴胺)的前体。
T1695 DL-O-Tyrosine

Amino Acids and Derivatives Metabolism
DL-O-Tyrosine 是苯丙氨酸的代谢物,是形成儿茶酚胺的前体。它被用作β-地中海贫血中蛋白质氧化损伤的生物标志物。
TN6749 3,5-Diiodo-L-tyrosine dihydrate

Others Others
3,5-Diiodo-L-tyrosine dihydrate 是一种天然产物。
T4890 3-Nitro-L-tyrosine

3-Nitrotyrosine,3-硝基-L-酪氨酸

Endogenous Metabolite Metabolism
3-Nitro-L-tyrosine (3-Nitrotyrosine) 在系统自免疫原性条件下,能够作无氮自由基修饰蛋白的生物标记物。
T5280 3-Chloro-L-Tyrosine

3-氯-L-酪氨酸,3-Chlorotyrosine,Chlorotyrosine

Others; Endogenous Metabolite Metabolism; Others
3-Chloro-L-Tyrosine (Chlorotyrosine) 是一种髓过氧化物酶催化氧化的特异性标志物,在从人动脉粥样硬化内膜分离的低密度脂蛋白中显著升高。
T5292 N-Acetyl-L-tyrosine

N-乙酰-L-酪氨酸,N-Acetyltyrosine,Ac-Tyr-OH

Others; Endogenous Metabolite Metabolism; Others
N-Acetyl-L-tyrosine (Ac-Tyr-OH) 是一种来源于AA 乙酰酶作用下的酪氨酸,和芳香族氨基酸脱羧酶缺乏症以及酪氨酸血症有关,能够作为儿茶酚胺的前体,用于治疗神经递质。
T13654 DL-m-Tyrosine

Others Others
DL-m-Tyrosine shows effects on Arabidopsis root growth.
T5568 H-Tyr(3-I)-OH

3-碘-L-酪氨酸,3-Iodo-L-tyrosine

Endogenous Metabolite Metabolism
H-Tyr(3-I)-OH (3-Iodo-L-tyrosine) 是酪氨酸羟化酶抑制剂和甲状腺激素 的中间体。
T1653 Liothyronine

Tresitope,O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine,碘噻罗宁,Triiodothyronine,三碘甲状腺原氨酸,L-3,3',5-Triiodothyronine,3,3',5-Triiodo-L-thyronine,Lyothyronine

Thyroid hormone receptor(THR); Endogenous Metabolite Endocrinology/Hormones; Metabolism
Liothyronine (Tresitope) 是一种人工合成的甲状腺激素,能够激活 β1 甲状腺激素受体 (TRβ1)。Liothyronine 能促进糖、蛋白质和脂肪三大物质的代谢,加速组织细胞的氧化过程,维持正常的基础代谢率,有利于机体的生长发育。
T1711 Harmine

Telepathine,去氢骆驼蓬碱

MAO; 5-HT Receptor; DYRK Cell Cycle/Checkpoint; GPCR/G Protein; Metabolism; Neuroscience; Tyrosine Kinase/Adaptors
Harmine (Telepathine) 是一种从山茱萸种子中分离出来的生物碱,具有抗癌和抗炎活性。它是双特异性酪氨酸磷酸化调节激酶抑制剂,对5-HT2A 血清素受体具有高亲和力,Ki 值为 397 nM。
T20555 Glycyltyrosine

NSC 118362,Gly Tyr,NSC-118362,Gly-Tyr,NSC118362,N-Glycyl-L-tyrosine

Others Others
Glycyltyrosine, a dipeptide composed of tyrosine and glycine, is an incomplete breakdown product of protein catabolism or protein digestion.
T2811 Harmine hydrochloride

telepathine hydrochloride,盐酸哈尔明碱

5-HT Receptor; DYRK; GluR Cell Cycle/Checkpoint; GPCR/G Protein; Neuroscience; Tyrosine Kinase/Adaptors
Harmine hydrochloride (telepathine hydrochloride) 是一种 DYRK 抑制剂,具有抗癌和抗炎活性。它对5-HT2A 血清素受体具有高亲和力,Ki 值为 397 nM。
TN1433 Batatasin III

FAK; Others; Akt Angiogenesis; Cytoskeletal Signaling; Others; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
Batatasin III 通过抑制上皮间质转化和 FAK-AKT 信号来抑制癌症迁移和侵袭,并具有抗癌活性。 Batatasin III 对整株生长有长期抑制作用,显示出抑制萌发活性。
T8152 6-Demethoxytangeretin

MAPK; ALK Angiogenesis; MAPK; Tyrosine Kinase/Adaptors
6-​Demethoxytangeretin 是一种从柑橘分离的黄酮。它能够促进 CRE 介导的转录 (与海马神经元的学习和记忆相关)。它具有抗炎和抗过敏作用,通过间变性淋巴瘤激酶和丝裂原活化蛋白激酶途径抑制人肥大细胞中 IL-6 的产生和基因表达。
T0610 Piceatannol

白皮杉醇,trans-Piceatannol,Astringenin

Apoptosis; Serine/threonin kinase; PKA; Syk; PKC; Autophagy Angiogenesis; Apoptosis; Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism; Tyrosine Kinase/Adaptors
Piceatannol (Astringenin) 是一种Syk 抑制剂,可降低由 TNF 诱导的 iNOS 表达,可研究急性肺损伤。它是存在于各种水果和蔬菜中天然存在的多酚二苯乙烯,可诱导细胞自噬和凋亡,具有抗癌和抗炎特性。
T6S0033 Crotonoside

巴豆苷;异鸟苷,巴豆苷,Isoguanosine,2-HYDROXYADENOSINE

Others; FLT; HDAC Angiogenesis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Others; Tyrosine Kinase/Adaptors
Crotonoside (Isoguanosine) 是从中草药巴豆中分离出来的一种天然产物。 它抑制 FLT3 和 HDAC3/6,有治疗急性髓性白血病 (AML)的研究潜力。
T5S0761 Nitidine chloride

Apoptosis; ERK; FAK; p38 MAPK; NF-κB; Topoisomerase; STAT; Parasite Angiogenesis; Apoptosis; Cytoskeletal Signaling; DNA Damage/DNA Repair; JAK/STAT signaling; MAPK; Microbiology/Virology; NF-κB; Stem Cells; Tyrosine Kinase/Adaptors
Nitidine chloride 是从Zanthoxylum nitidum (Roxb) DC 中分离得到的,具有抗疟疾活性。它通过多个靶点通路,起抗癌作用,抑制STAT3、DNA 拓扑异构酶1和2A、ERK 和c-Src/FAK 相关信号通路。它通过MAPK 和NF-kB 途径抑制Lps 诱导的炎性细胞因子的产生。
T1181 Gefitinib

ZD1839,吉非替尼

EGFR; Tyrosine Kinases; Autophagy Angiogenesis; Autophagy; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Gefitinib (ZD1839) 是一种 EGFR 一代抑制剂,具有口服活性,抑制 EGFR 19 Del 和 L858R 突变。Gefitinib 具有抗肿瘤活性,用于治疗 EGFR 突变的非小细胞肺癌。Gefitinib 用药会产生 EGFR C797S 耐药突变。
T3122 Fangchinoline

Tetrandrine B,防己诺林碱,(+)-Limacine,Hanfangichin B,防己醇灵,(+)-Fangchinoline

Apoptosis; FAK; HIV Protease; Autophagy Angiogenesis; Apoptosis; Autophagy; Cytoskeletal Signaling; Microbiology/Virology; Proteases/Proteasome; Tyrosine Kinase/Adaptors
Fangchinoline (Tetrandrine B) 是从Stephaniatetrandra 中分离出来的,一种具有广泛生物学活性的天然产物。它是新型HIV-1抑制剂,通过损害 gp160 蛋白水解过程来抑制 HIV-1 复制。它靶向Focal adhesion kinase (FAK)并抑制肿瘤细胞中 FAK 介导的的信号传导途径。
T2755 Rhoifolin

野漆树苷,Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside

Others; p38 MAPK; NF-κB; transporter; IGF-1R; Autophagy Autophagy; MAPK; Metabolism; NF-κB; Others; Tyrosine Kinase/Adaptors
Rhoifolin (Apigenin 7-O-neohesperidoside) 是从琯溪蜜柚叶子分离的一种黄酮糖苷。它通过 RANKL 诱导的NF-κB 和MAPK 途径改善钛颗粒刺激的骨溶解并减少破骨细胞生成。它通过增强脂联素分泌,胰岛素受体-β的酪氨酸磷酸化和GLUT4易位有助于治疗糖尿病并发症。
T2862 Desaminotyrosine

Phloretate,3-(4-Hydroxyphenyl)propanoic acid,Hydro-p-coumaric acid,对羟基苯丙酸,3-(4-Hydroxyphenyl)propionic acid,Phloretic acid,根皮酸

Others; Influenza Virus; Endogenous Metabolite Metabolism; Microbiology/Virology; Others
Desaminotyrosine (3-(4-Hydroxyphenyl)propionic acid) 是一种与微生物相关的代谢物,通过增强 I 型干扰素信号传导来预防流感。
T40667 L-Azatyrosine

Others Others
L-Azatyrosine, an antitumor antibiotic derived from Streptomyces chibaensis, exhibits the ability to restore the normal phenotypic behavior of transformed cells that carry oncogenic Ras genes.
TN6561 N-trans-p-Coumaroyltyrosine

N-trans-p-Coumaroyltyrosine 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6561,CAS号为 77201-66-2。
T6S0923 Hypericin

Hypericine,金丝桃素,Cyclosan

Apoptosis; Antiviral; Influenza Virus; Tyrosine Kinases; Antibacterial; PKC Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; Immunology/Inflammation; Microbiology/Virology; Tyrosine Kinase/Adaptors
Hypericin (Cyclosan) 是贯叶连翘的提取物,有抗菌、抗病毒、抗肿瘤和抗抑郁作用。
T4858 4-​Hydroxyphenylpyruvic acid

4-羟苯基丙酮酸,4-Hydroxyphenylpyruvic acid

Endogenous Metabolite Metabolism
4-Hydroxyphenylpyruvic acid 是一种苯丙氨酸代谢的中间产物,是一种酶抑制剂。
TQ0065 Pseudobufarenogin

伪异沙蟾毒精,ψ-Bufarenogin

Others Others
Pseudobufarenogin (ψ-Bufarenogin) 是一种蟾蜍毒素提取物,活性背景未知。
T22974 Methyl 2,5-dihydroxycinnamate

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Methyl 2,5-dihydroxycinnamate 是 erbstatin 类似物,是一种高效、稳定的 EGF 受体相关酪氨酸激酶的抑制剂。
T3737 3-(2,4-Dihydroxyphenyl)propanoic acid

3-(2,4-二羟基苯)丙酸,Hydroumbellic acid,2,4-Dihydroxyhydrocinnamic acid

Tyrosinase Proteases/Proteasome
3-(2,4-Dihydroxyphenyl)propanoic acid (Hydroumbellic acid) 是竞争性酪氨酸酶 (tyrosinase) 抑制剂,可抑制 L-Tyrosine 和 DL-DOPA,IC50和 Ki 分别为 3.02 μM 和 11.5 μM。
TN1096 Ginsenoside Ra1

人参皂苷 Ra1,人参皂苷Ra1

Others; Tyrosine Kinases Others; Tyrosine Kinase/Adaptors
Ginsenoside Ra1 是来自人参的成分。 Ginsenoside Ra1 对缺氧/复氧诱导的蛋白酪氨酸激酶 (PTK) 活化具有显着抑制作用。
T1238 Daidzein

大豆素,Isoflavone,黄豆苷元

Endogenous Metabolite; PPAR DNA Damage/DNA Repair; Metabolism
Daidzein (Isoflavone) 是一种来自大豆的异黄酮提取物,是酪氨酸激酶抑制剂染料木黄酮的无活性类似物,具有抗氧化和植物雌激素特性。
TN1053 Aloe-emodin-8-O-β-D-glucopyranoside

Aloe-emodin-8-O-beta-D-glucopyranoside,芦荟大黄素-8-O-β-D-葡萄糖苷

Phosphatase Metabolism
Aloe-emodin-8-O-β-D-glucopyranoside (Aloe-emodin-8-O-beta-D-glucopyranoside) 是一种分离自Saussrurea lappa 中的化合物,是一种温和的人类蛋白酪氨酸磷酸酶 1B 抑制剂,其IC50=26.6 μM。
T4S0295 Apigenin 7-glucoside

波斯菊,Cosmetin,Cosmosiin,Cosmosioside,Apigenin-7-O-β-D-glucopyranoside,芹甙元-7-葡萄糖苷,Thalictiin,Apigetrin

Reactive Oxygen Species; HIV Protease Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
Apigenin 7-glucoside (Cosmosiin) 是一种 ROS 清除剂,具有抗增殖、抗氧化作用。
T7851 Tyramine hydrochloride

盐酸酪胺,酪胺盐酸盐

Others; Endogenous Metabolite Metabolism; Others
Tyramine hydrochloride 是一种氨基酸,有助于调节血压。其中 Tyramine 天然存在于体内,并存在于某些食物中。
T5755 Aloesin

Tyrosinase Proteases/Proteasome
Aloesin 是芦荟的活性成分之一,能够通过 MAPK 信号通路发挥抗癌作用,并具有抗炎、紫外线保护和抗菌作用。
T21977 p-Cresyl sulfate

Others Others
p-Cresyl Sulfate 是主要的尿毒症毒素,存在于慢性肾病患者的血液,来源于肝脏中酪氨酸和苯丙氨酸的代谢物。
T4829 3-Hydroxyphenylacetic acid

Others; Endogenous Metabolite Metabolism; Others
3-Hydroxyphenylacetic acid 是内源性代谢产物的一种。
T1737 Genistein

NPI 031L,三叶草,染料木素,金雀异黄酮

Apoptosis; EGFR; Endogenous Metabolite; Autophagy Angiogenesis; Apoptosis; Autophagy; JAK/STAT signaling; Metabolism; Tyrosine Kinase/Adaptors
Genistein (NPI 031L) 是一种大豆异黄酮,是一种多重的酪氨酸激酶抑制剂,通过改变细胞凋亡,细胞周期和血管生成以及抑制转移对多种癌症有化疗作用。
Fr16741 Oxindole

2-吲哚酮,板蓝根,Indolin-2-one

Others; HIV Protease Microbiology/Virology; Others; Proteases/Proteasome
Oxindole (Indolin-2-one) 是一种芳族杂环砌块,其衍生物是激酶抑制剂研究中的主要成分。
T2336 Vitamin K2

Menatetrenone,四烯甲萘醌

Endogenous Metabolite Metabolism
Vitamin K2 (Menatetrenone) 是内源性代谢产物的一种。
T6427 Butein

2’,3,4,4’-tetrahydroxy Chalcone,紫铆因

Apoptosis; EGFR; Others; PDE; Autophagy Angiogenesis; Apoptosis; Autophagy; JAK/STAT signaling; Metabolism; Others; Tyrosine Kinase/Adaptors
Butein (2’,3,4,4’-tetrahydroxy Chalcone) 是一种 cAMP 特异性PDE 抑制剂,也是蛋白酪氨酸激酶抑制剂,还是一种SIRT1激活剂。它通过 AKT 和 ERK/p38 MAPK 通路,靶向 FoxO3a 使 HeLa 细胞对 Cisplatin 敏感。
TN1470 Cassiaside B2

决明子苷B2

Phosphatase; MAO; 5-HT Receptor GPCR/G Protein; Metabolism; Neuroscience
Cassiaside B2 是蛋白酪氨酸磷酸酶1B (PTP1B) 和人单胺氧化酶A (hMAO-A) 的抑制剂。Cassiaside B2是 5-HT2C 受体的激动剂, 具有抗过敏活性。Cassiaside B2 是萘吡喃酮参比提取物(NRE)的有效成分之一。
T3377 L-Phenylalanine

L-苯丙氨酸,(S)-2-Amino-3-phenylpropionic acid,phenylalanine,3-Phenyl-L-alanine

Calcium Channel; Endogenous Metabolite; iGluR Membrane transporter/Ion channel; Metabolism; Neuroscience
L-Phenylalanine (3-Phenyl-L-alanine) 是分离自大肠杆菌的必需氨基酸,是 NMDARs(KB573 μM) 和非 NMDARs 的甘氨酸和谷氨酸结合位点的竞争性拮抗剂,用于食品香料和药品的生产中。它是一种电压依赖性 α2δ 亚基 Ca2+通道拮抗剂,Ki 为 980 nM。
TN2019 Orobol

3'-Hydroxygenistein,3’,4’,5,7-tetrahydroxy-isoflavon,3',4',5,7-四羟基异黄酮

BCL; Caspase; PI3K Apoptosis; PI3K/Akt/mTOR signaling; Proteases/Proteasome
Orobol (3’,4’,5,7-tetrahydroxy-isoflavon) 是酪氨酸特异性蛋白激酶和磷脂酰肌醇转换的抑制剂。Orobol 抑制 PI3K,对 PI3K α/β/γ/K/δ 的 IC50 为 3.46-5.27 μM。 Orobol 具有抗皮肤老化和抗肥胖的作用。
TN1440 Beta-Hydroxyisovalerylshikonin

EGFR; Tyrosine Kinases; Prostaglandin Receptor; Src; AMPK; Fatty Acid Synthase Angiogenesis; Chromatin/Epigenetic; GPCR/G Protein; Immunology/Inflammation; JAK/STAT signaling; Metabolism; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
Beta-hydroxyisovalerylshikonin 是分离自Lithospermium radix 的天然产物,具有抑制PTK 的作用, 对 EGFR 和 v-Src 受体作用的IC50分别为 0.7 μM 和 1 μM。它对多种肿瘤细胞系均有抑制作用,可以高效诱导 NCI-H522 和 DMS114 细胞的死亡。
T4781 N-Acetyl-L-phenylalanine

N-Ac-Phenylalanine,N-乙酰-L-苯丙氨酸

Others; Endogenous Metabolite Metabolism; Others
N-Acetyl-L-phenylalanine (N-Ac-Phenylalanine) 是一种大肠杆菌中的主要酰基氨基酸,由 L-苯丙氨酸和乙酰辅酶 A 合成。
TN2111 Prunin

Naringenin 7-0-glucoside,柚皮素-7-O-葡萄糖苷

Phosphatase; Anti-infection; Virus Protease Metabolism; Microbiology/Virology
Prunin (Naringenin 7-0-glucoside) 是一种人肠道病毒 A71 抑制剂。它抑制蛋白酪氨酸磷酸酶 1B,IC50值为 5.5 μM。
T5290 (S)-2-Hydroxy-3-phenylpropanoic acid

L-(−)-3-Phenyllactic acid,L-3-苯乳酸

Others; Endogenous Metabolite Metabolism; Others
(S)-2-Hydroxy-3-phenylpropanoic acid (L-(−)-3-Phenyllactic acid) 是苯丙氨酸的代谢产物。苯丙酮尿症患者体液中苯丙氨酸的水平升高。
T4518 Licochalcone D

ERK; NF-κB MAPK; NF-κB
Licochalcone D 是一种 NF-κB p65的有效抑制剂,是一种存在于 Glycyrrhiza inflate 中的黄酮类化合物,具有抗氧化、抗炎、抗癌等作用。
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天然产物

L-Tyrosine
Cat.No: T0493
Synonym: Tyrosine,P-Tyrosine,L-酪氨酸,L-p-Tyrosine,(S)-Tyrosine,酪氨酸
Target: Amino Acids and Derivatives, Endogenous Metabolite
D-Tyrosine
Cat.No: TN1545
Synonym:
Target: Tyrosinase
DL-Tyrosine
Cat.No: TN1596
Synonym:
Target: Others
DL-O-Tyrosine
Cat.No: T1695
Synonym:
Target: Amino Acids and Derivatives
3,5-Diiodo-L-tyrosine dihydrate
Cat.No: TN6749
Synonym:
Target: Others
3-Nitro-L-tyrosine
Cat.No: T4890
Synonym: 3-Nitrotyrosine,3-硝基-L-酪氨酸
Target: Endogenous Metabolite
3-Chloro-L-Tyrosine
Cat.No: T5280
Synonym: 3-氯-L-酪氨酸,3-Chlorotyrosine,Chlorotyrosine
Target: Others, Endogenous Metabolite
N-Acetyl-L-tyrosine
Cat.No: T5292
Synonym: N-乙酰-L-酪氨酸,N-Acetyltyrosine,Ac-Tyr-OH
Target: Others, Endogenous Metabolite
DL-m-Tyrosine
Cat.No: T13654
Synonym:
Target: Others
H-Tyr(3-I)-OH
Cat.No: T5568
Synonym: 3-碘-L-酪氨酸,3-Iodo-L-tyrosine
Target: Endogenous Metabolite
Liothyronine
Cat.No: T1653
Synonym: Tresitope,O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine,碘噻罗宁,Triiodothyronine,三碘甲状腺原氨酸,L-3,3',5-Triiodothyronine,3,3',5-Triiodo-L-thyronine,Lyothyronine
Target: Thyroid hormone receptor(THR), Endogenous Metabolite
Harmine
Cat.No: T1711
Synonym: Telepathine,去氢骆驼蓬碱
Target: MAO, 5-HT Receptor, DYRK
Glycyltyrosine
Cat.No: T20555
Synonym: NSC 118362,Gly Tyr,NSC-118362,Gly-Tyr,NSC118362,N-Glycyl-L-tyrosine
Target: Others
Harmine hydrochloride
Cat.No: T2811
Synonym: telepathine hydrochloride,盐酸哈尔明碱
Target: 5-HT Receptor, DYRK, GluR
Batatasin III
Cat.No: TN1433
Synonym:
Target: FAK, Others, Akt
6-Demethoxytangeretin
Cat.No: T8152
Synonym:
Target: MAPK, ALK
Piceatannol
Cat.No: T0610
Synonym: 白皮杉醇,trans-Piceatannol,Astringenin
Target: Apoptosis, Serine/threonin kinase, PKA, Syk, PKC, Autophagy
Crotonoside
Cat.No: T6S0033
Synonym: 巴豆苷;异鸟苷,巴豆苷,Isoguanosine,2-HYDROXYADENOSINE
Target: Others, FLT, HDAC
Nitidine chloride
Cat.No: T5S0761
Synonym:
Target: Apoptosis, ERK, FAK, p38 MAPK, NF-κB, Topoisomerase, STAT, Parasite
Gefitinib
Cat.No: T1181
Synonym: ZD1839,吉非替尼
Target: EGFR, Tyrosine Kinases, Autophagy
Fangchinoline
Cat.No: T3122
Synonym: Tetrandrine B,防己诺林碱,(+)-Limacine,Hanfangichin B,防己醇灵,(+)-Fangchinoline
Target: Apoptosis, FAK, HIV Protease, Autophagy
Rhoifolin
Cat.No: T2755
Synonym: 野漆树苷,Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside
Target: Others, p38 MAPK, NF-κB, transporter, IGF-1R, Autophagy
Desaminotyrosine
Cat.No: T2862
Synonym: Phloretate,3-(4-Hydroxyphenyl)propanoic acid,Hydro-p-coumaric acid,对羟基苯丙酸,3-(4-Hydroxyphenyl)propionic acid,Phloretic acid,根皮酸
Target: Others, Influenza Virus, Endogenous Metabolite
L-Azatyrosine
Cat.No: T40667
Synonym:
Target: Others
N-trans-p-Coumaroyltyrosine
Cat.No: TN6561
Synonym:
Target:
Hypericin
Cat.No: T6S0923
Synonym: Hypericine,金丝桃素,Cyclosan
Target: Apoptosis, Antiviral, Influenza Virus, Tyrosine Kinases, Antibacterial, PKC
4-​Hydroxyphenylpyruvic acid
Cat.No: T4858
Synonym: 4-羟苯基丙酮酸,4-Hydroxyphenylpyruvic acid
Target: Endogenous Metabolite
Pseudobufarenogin
Cat.No: TQ0065
Synonym: 伪异沙蟾毒精,ψ-Bufarenogin
Target: Others
Methyl 2,5-dihydroxycinnamate
Cat.No: T22974
Synonym:
Target: EGFR
3-(2,4-Dihydroxyphenyl)propanoic acid
Cat.No: T3737
Synonym: 3-(2,4-二羟基苯)丙酸,Hydroumbellic acid,2,4-Dihydroxyhydrocinnamic acid
Target: Tyrosinase
Ginsenoside Ra1
Cat.No: TN1096
Synonym: 人参皂苷 Ra1,人参皂苷Ra1
Target: Others, Tyrosine Kinases
Daidzein
Cat.No: T1238
Synonym: 大豆素,Isoflavone,黄豆苷元
Target: Endogenous Metabolite, PPAR
Aloe-emodin-8-O-β-D-glucopyranoside
Cat.No: TN1053
Synonym: Aloe-emodin-8-O-beta-D-glucopyranoside,芦荟大黄素-8-O-β-D-葡萄糖苷
Target: Phosphatase
Apigenin 7-glucoside
Cat.No: T4S0295
Synonym: 波斯菊,Cosmetin,Cosmosiin,Cosmosioside,Apigenin-7-O-β-D-glucopyranoside,芹甙元-7-葡萄糖苷,Thalictiin,Apigetrin
Target: Reactive Oxygen Species, HIV Protease
Tyramine hydrochloride
Cat.No: T7851
Synonym: 盐酸酪胺,酪胺盐酸盐
Target: Others, Endogenous Metabolite
Aloesin
Cat.No: T5755
Synonym:
Target: Tyrosinase
p-Cresyl sulfate
Cat.No: T21977
Synonym:
Target: Others
3-Hydroxyphenylacetic acid
Cat.No: T4829
Synonym:
Target: Others, Endogenous Metabolite
Genistein
Cat.No: T1737
Synonym: NPI 031L,三叶草,染料木素,金雀异黄酮
Target: Apoptosis, EGFR, Endogenous Metabolite, Autophagy
Oxindole
Cat.No: Fr16741
Synonym: 2-吲哚酮,板蓝根,Indolin-2-one
Target: Others, HIV Protease
Vitamin K2
Cat.No: T2336
Synonym: Menatetrenone,四烯甲萘醌
Target: Endogenous Metabolite
Butein
Cat.No: T6427
Synonym: 2’,3,4,4’-tetrahydroxy Chalcone,紫铆因
Target: Apoptosis, EGFR, Others, PDE, Autophagy
Cassiaside B2
Cat.No: TN1470
Synonym: 决明子苷B2
Target: Phosphatase, MAO, 5-HT Receptor
L-Phenylalanine
Cat.No: T3377
Synonym: L-苯丙氨酸,(S)-2-Amino-3-phenylpropionic acid,phenylalanine,3-Phenyl-L-alanine
Target: Calcium Channel, Endogenous Metabolite, iGluR
Orobol
Cat.No: TN2019
Synonym: 3'-Hydroxygenistein,3’,4’,5,7-tetrahydroxy-isoflavon,3',4',5,7-四羟基异黄酮
Target: BCL, Caspase, PI3K
Beta-Hydroxyisovalerylshikonin
Cat.No: TN1440
Synonym:
Target: EGFR, Tyrosine Kinases, Prostaglandin Receptor, Src, AMPK, Fatty Acid Synthase
N-Acetyl-L-phenylalanine
Cat.No: T4781
Synonym: N-Ac-Phenylalanine,N-乙酰-L-苯丙氨酸
Target: Others, Endogenous Metabolite
Prunin
Cat.No: TN2111
Synonym: Naringenin 7-0-glucoside,柚皮素-7-O-葡萄糖苷
Target: Phosphatase, Anti-infection, Virus Protease
(S)-2-Hydroxy-3-phenylpropanoic acid
Cat.No: T5290
Synonym: L-(−)-3-Phenyllactic acid,L-3-苯乳酸
Target: Others, Endogenous Metabolite
Licochalcone D
Cat.No: T4518
Synonym:
Target: ERK, NF-κB
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Cat. No. Product Name Species Expression System
TMPY-02587 Tyrosine Hydroxylase Protein, Mouse, Recombinant (His)

tyrosine hydroxylase

Mouse Baculovirus Insect Cells
Tyrosine Hydroxylase Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 58 kDa and the accession number is P24529.
TMPY-02401 Tyrosine Hydroxylase Protein, Human, Recombinant (His)

tyrosine hydroxylase,DYT14,TYH,DYT5b

Human Baculovirus Insect Cells
Tyrosine Hydroxylase Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number is P07101-3.
TMPH-02271 BTK Protein, Human, Recombinant (His)

BPK,AGMX1,ATK,B-cell progenitor kinase,Tyrosine-pro...

Human Baculovirus Insect Cells
Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in...
TMPY-00548 HGFR/c-Met Protein, Cynomolgus, Rhesus, Recombinant (His)

MET proto-oncogene, receptor tyrosine kinase

Cynomolgus,Rhesus HEK293 Cells
HGFR/c-Met Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 103.1 kDa and the accession number is G7MM61.
TMPY-00246 HER3/ERBB3 Protein, Rhesus, Recombinant

erb-b2 receptor tyrosine kinase 3

Rhesus HEK293 Cells
HER3/ERBB3 Protein, Rhesus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 69.5 kDa and the accession number is XP_001113953.2.
TMPY-02813 ErbB4 Protein, Human, Rhesus, Recombinant (His)

erb-b2 receptor tyrosine kinase 4

Human,Rhesus HEK293 Cells
ErbB4 Protein, Human, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.1 kDa and the accession number is Q15303-1.
TMPY-02477 HER3/ERBB3 Protein, Rhesus, Recombinant (His)

erb-b2 receptor tyrosine kinase 3

Rhesus HEK293 Cells
HER3/ERBB3 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.1 kDa and the accession number is XP_005571238.1&XP_001113953.2.
TMPY-00636 HER2/ERBB2 Protein, Cynomolgus, Recombinant (His)

erb-b2 receptor tyrosine kinase 2,EGFR2

Cynomolgus HEK293 Cells
HER2/ERBB2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.8 kDa and the accession number is G7PUM4.
TMPY-03024 HER3/ERBB3 Protein, Rat, Recombinant (His)

erb-b2 receptor tyrosine kinase 3

Rat HEK293 Cells
HER3/ERBB3 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.9 kDa and the accession number is A6KSF8.
TMPY-01944 HER2/ERBB2 Protein, Rat, Recombinant (His)

EGFR2,erb-b2 receptor tyrosine kinase 2

Rat HEK293 Cells
HER2/ERBB2 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.2 kDa and the accession number is AAH61863.1.
TMPY-03719 HER2/ERBB2 Protein, Canine, Recombinant (His)

erb-b2 receptor tyrosine kinase 2,EGFR2

Canine HEK293 Cells
HER2/ERBB2 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.4 kDa and the accession number is A8WED5.
TMPJ-00412 VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)

Vascular endothelial growth factor receptor 1,Vascular perme...

Human HEK293 Cells
Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 is widely expressed in human tissues including normal lung, placenta, liver, kidney, heart and brain tissues. It is specifically expressed in most of the vascular endothelial cellsand peripheral blood monocytes. VEGFR-1 contains seven Ig-like C2-type domains and one protein kinas...
TMPY-01601 AXL Protein, Human, Recombinant (His)

UFO,ARK,JTK11,AXL receptor tyrosine kinase,Tyro7

Human HEK293 Cells
AXL Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.5 kDa and the accession number is AAB20305.1.
TMPY-03066 FLT3 Ligand Protein, Mouse, Recombinant (hFc)

Ly72L,Flt3lg,fms related tyrosine kinase 3 ligand,F...

Mouse HEK293 Cells
FLT3 Ligand Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.4 kDa and the accession number is P49772-1.
TMPY-06873 FLT3 Ligand Protein, Human, Recombinant

FLT3LG,fms related tyrosine kinase 3 ligand,FLT3L,F...

Human E. coli
FLT3 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.75 kDa and the accession number is P49771-1.
TMPY-03215 FLT3 Ligand Protein, Human, Recombinant (His)

fms related tyrosine kinase 3 ligand,FLT3L,FLT3LG,F...

Human Baculovirus Insect Cells
FLT3 Ligand Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 20.2 kDa and the accession number is P49771-1.
TMPY-04125 PTP1B Protein, Human, Recombinant (His)

protein tyrosine phosphatase, non-receptor type 1,P...

Human E. coli
PTP1B, also known as PTPN1, belongs to the protein-tyrosine phosphatase (PTP) family. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTP1B contains 1 tyrosine-protein p...
TMPY-04649 ROR1 Protein, Human, Recombinant (His)

dJ537F10.1,NTRKR1,receptor tyrosine kinase-like orp...

Human HEK293 Cells
ROR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.4 kDa and the accession number is Q01973.
TMPY-00930 TIE2 Protein, Human, Recombinant (His & hFc)

VMCM1,TIE2,CD202B,TEK tyrosine kinase, endothelial,...

Human HEK293 Cells
TIE2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 108.5 kDa and the accession number is AAA61139.1.
TMPY-01064 TIE2 Protein, Human, Recombinant (His)

TIE2,VMCM,CD202B,TEK tyrosine kinase, endothelial,V...

Human HEK293 Cells
TIE2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82 kDa and the accession number is AAA61139.1.
TMPY-05394 ROR2 Protein, Human, Recombinant (His)

BDB,BDB1,NTRKR2,receptor tyrosine kinase-like orpha...

Human HEK293 Cells
ROR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.8 kDa and the accession number is Q01974.
TMPY-03548 PTPN12 Protein, Human, Recombinant

protein tyrosine phosphatase, non-receptor type 12,...

Human Baculovirus Insect Cells
PTPN12 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 41.8 kDa and the accession number is AAA36529.1.
TMPY-01247 FLT3 Protein, Human, Recombinant (T227M, His)

FLK2,FLK-2,CD135,STK1,fms-related tyrosine kinase 3

Human HEK293 Cells
FLT3 Protein, Human, Recombinant (T227M, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.7 kDa and the accession number is P36888-1.
TMPY-00637 FLT1 Protein, Human, Recombinant (aa 1-328, His)

VEGFR-1,fms-related tyrosine kinase 1,VEGFR1,FLT,FL...

Human HEK293 Cells
FLT1 Protein, Human, Recombinant (aa 1-328, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.6 kDa and the accession number is L7RSL3.
TMPY-00882 Mer Protein, Human, Recombinant (His & hFc)

RP38,c-Eyk,c-mer,Tyro12,MER proto-oncogene, tyrosine

Human HEK293 Cells
Mer Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 80 kDa and the accession number is Q12866.
TMPY-04330 Mer Protein, Human, Recombinant

MER proto-oncogene, tyrosine kinase,RP38,MER,c-mer,...

Human HEK293 Cells
Mer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 54 kDa and the accession number is Q12866.
TMPY-01896 HGFR/c-Met Protein, Mouse, Recombinant (His)

MET proto-oncogene, receptor tyrosine kinase,HGFR,c...

Mouse HEK293 Cells
HGFR/c-Met Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 102 kDa and the accession number is EDL13881.1.
TMPJ-00778 HER2/ERBB2 Protein, Human, Recombinant (His)

TKR1,Metastatic lymph node gene 19 protein,ERBB2,Proto-oncog...

Human HEK293 Cells
HER2/ERBB2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 90-120 KDa and the accession number is P04626.
TMPY-01936 VEGFR3/FLT4 Protein, Mouse, Recombinant (His)

Flt-4,VEGFR-3,Chy,fms related tyrosine kinase 4,VEG...

Mouse HEK293 Cells
VEGFR3/FLT4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession number is P35917-1.
TMPY-03484 TCPTP Protein, Human, Recombinant

TCPTP,protein tyrosine phosphatase, non-receptor ty...

Human Baculovirus Insect Cells
TCPTP Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 36.8 kDa and the accession number is P17706-1.
TMPY-04384 Src Protein, Human, Recombinant (His & GST)

c-SRC,p60-Src,ASV,SRC1,SRC proto-oncogene, non-receptor ...

Human Baculovirus Insect Cells
Src Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 87.7 kDa and the accession number is P12931-1.
TMPY-01084 TrkA Protein, Human, Recombinant (His)

TRK1,TRK,TRKA,neurotrophic tyrosine kinase, recepto...

Human HEK293 Cells
TrkA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.5 kDa and the accession number is P04629-1.
TMPY-01296 HGFR/c-Met Protein, Human, Recombinant (His)

AUTS9,MET proto-oncogene, receptor tyrosine kinase,...

Human HEK293 Cells
HGFR/c-Met Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 103 kDa and the accession number is A0A024R759.
TMPY-02231 TrkB Protein, Mouse, Recombinant (His)

trk-B,neurotrophic tyrosine kinase, receptor, type ...

Mouse HEK293 Cells
TrkB Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is P15209-2.
TMPY-02365 HER3/ERBB3 Protein, Mouse, Recombinant (His)

Erbb-3r,Erbb3r,erb-b2 receptor tyrosine kinase 3,C7...

Mouse HEK293 Cells
HER3/ERBB3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70 kDa and the accession number is Q61526.
TMPY-00751 TrkB Protein, Human, Recombinant (His)

trk-B,GP145-TrkB/GP95-TrkB,neurotrophic tyrosine ki...

Human HEK293 Cells
TrkB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is Q16620-2.
TMPY-05308 CD45 Protein, Human, Recombinant (aa 1-529, His)

GP180,B220,L-CA,protein tyrosine phosphatase, recep...

Human HEK293 Cells
CD45 Protein, Human, Recombinant (aa 1-529, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.4 kDa and the accession number is P08575-5.
TMPY-05748 CD45 Protein, Human, Recombinant (aa 26-577, His)

L-CA,T200,LCA,B220,protein tyrosine phosphatase, re...

Human HEK293 Cells
CD45 Protein, Human, Recombinant (aa 26-577, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.2 kDa and the accession number is P08575-3.
TMPY-02469 HER2/ERBB2 Protein, Mouse, Recombinant (hFc)

EGFR2,c-erbB2,l11Jus8,Erbb-2,mKIAA3023,Neu,erb-b2 receptor <...

Mouse HEK293 Cells
HER2/ERBB2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 96.7 kDa and the accession number is P70424.
TMPY-00949 VEGFR3/FLT4 Protein, Human, Recombinant (His)

VEGFR-3,PCL,FLT41,VEGF Receptor 3,VEGFR3,FLT-4,fms related <...

Human HEK293 Cells
VEGFR3/FLT4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86 kDa and the accession number is P35916-1.
TMPY-02314 HER2/ERBB2 Protein, Mouse, Recombinant (His)

HER2,c-erbB2,erb-b2 receptor tyrosine kinase 2,Neu,...

Mouse HEK293 Cells
HER2/ERBB2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.1 kDa and the accession number is P70424.
TMPY-01289 DDR1 Protein, Human, Recombinant (His)

RTK6,DDR,TRKE,PTK3,NTRK4,NEP,PTK3A,MCK10,EDDR1,HGK2,CD167,CA...

Human HEK293 Cells
DDR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is A0A024RCQ1.
TMPY-04396 C-ABL/ABL1 Protein, Human, Recombinant (GST)

v-abl,ABL,JTK7,ABL proto-oncogene 1, non-receptor tyrosi...

Human Baculovirus Insect Cells
c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cytosol, and c-Abl is present in the nucleus as well. c-Abl is a non-receptor tyrosine kinase that participates in multiple signaling pathways linking the cell surface, cytoskeleton, and the nucleus. Recent in vitro studies have also linked c-Abl to amyloid-beta-induced toxicity an...
TMPH-02823 Peptide YY/PYY Protein, Mouse, Recombinant (GST)

Peptide tyrosine tyrosine,Pyy,Peptide YY

Mouse E. coli
This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.
TMPH-01852 Peptide YY/PYY Protein, Human, Recombinant (GST)

Peptide tyrosine tyrosine,PYY-I,PYY,Peptid...

Human E. coli
This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. Peptide YY/PYY Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 31.1 kDa and the accession number is P10082.
TMPJ-01081 Dtk Protein, Human, Recombinant (His)

RSE,SKY,DTK,Tyrosine-protein kinase DTK,Tyrosin...

Human HEK293 Cells
Axl (Ufo, Ark), Dtk (Sky, Tyro3, Rse, Brt) and Mer (human and mouse homologues of chicken cEyk)constitute a new receptor tyrosine kinase subfamily. The extracellular domain of these proteins contain two Ig-like motifs and two fibronectin type III motifs. This characteristic topology is also found in neural cell adhesion molecules and in receptor tyrosine phosphatases. All three receptors bind the vitamin K-dependent protein growth-arrest specific gene 6 (Gas6) which is structurally related to th...
TMPY-05049 TIE2 Protein, Rhesus, Recombinant (His)

TEK tyrosine kinase, endothelial

Rhesus HEK293 Cells
TIE2 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.2 kDa and the accession number is G7NFP9.
TMPJ-01017 Dtk Protein, Mouse, Recombinant (hFc)

tyro3,Tyrosine-protein kinase receptor TYRO3,Ty...

Mouse HEK293 Cells
Dtk Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number is P55144.
TMPJ-01018 Dtk Protein, Mouse, Recombinant (mFc)

TK19-2,Tyrosine-protein kinase RSE,Etk2/tyro3,T...

Mouse HEK293 Cells
Dtk Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 60-90 KDa and the accession number is P55144.
TMPY-02508 TIE2 Protein, Rat, Recombinant (hFc)

TEK tyrosine kinase, endothelial

Rat HEK293 Cells
TIE2 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 108 kDa and the accession number is A6JRG8.
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重组蛋白

Tyrosine Hydroxylase Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02587
Species: Mouse
Expression System: Baculovirus Insect Cells
Tyrosine Hydroxylase Protein, Human, Recombinant (His)
Cat.No: TMPY-02401
Species: Human
Expression System: Baculovirus Insect Cells
BTK Protein, Human, Recombinant (His)
Cat.No: TMPH-02271
Species: Human
Expression System: Baculovirus Insect Cells
HGFR/c-Met Protein, Cynomolgus, Rhesus, Recombinant (His)
Cat.No: TMPY-00548
Species: Cynomolgus,Rhesus
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Rhesus, Recombinant
Cat.No: TMPY-00246
Species: Rhesus
Expression System: HEK293 Cells
ErbB4 Protein, Human, Rhesus, Recombinant (His)
Cat.No: TMPY-02813
Species: Human,Rhesus
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-02477
Species: Rhesus
Expression System: HEK293 Cells
HER2/ERBB2 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-00636
Species: Cynomolgus
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Rat, Recombinant (His)
Cat.No: TMPY-03024
Species: Rat
Expression System: HEK293 Cells
HER2/ERBB2 Protein, Rat, Recombinant (His)
Cat.No: TMPY-01944
Species: Rat
Expression System: HEK293 Cells
HER2/ERBB2 Protein, Canine, Recombinant (His)
Cat.No: TMPY-03719
Species: Canine
Expression System: HEK293 Cells
VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00412
Species: Human
Expression System: HEK293 Cells
AXL Protein, Human, Recombinant (His)
Cat.No: TMPY-01601
Species: Human
Expression System: HEK293 Cells
FLT3 Ligand Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-03066
Species: Mouse
Expression System: HEK293 Cells
FLT3 Ligand Protein, Human, Recombinant
Cat.No: TMPY-06873
Species: Human
Expression System: E. coli
FLT3 Ligand Protein, Human, Recombinant (His)
Cat.No: TMPY-03215
Species: Human
Expression System: Baculovirus Insect Cells
PTP1B Protein, Human, Recombinant (His)
Cat.No: TMPY-04125
Species: Human
Expression System: E. coli
ROR1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04649
Species: Human
Expression System: HEK293 Cells
TIE2 Protein, Human, Recombinant (His & hFc)
Cat.No: TMPY-00930
Species: Human
Expression System: HEK293 Cells
TIE2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01064
Species: Human
Expression System: HEK293 Cells
ROR2 Protein, Human, Recombinant (His)
Cat.No: TMPY-05394
Species: Human
Expression System: HEK293 Cells
PTPN12 Protein, Human, Recombinant
Cat.No: TMPY-03548
Species: Human
Expression System: Baculovirus Insect Cells
FLT3 Protein, Human, Recombinant (T227M, His)
Cat.No: TMPY-01247
Species: Human
Expression System: HEK293 Cells
FLT1 Protein, Human, Recombinant (aa 1-328, His)
Cat.No: TMPY-00637
Species: Human
Expression System: HEK293 Cells
Mer Protein, Human, Recombinant (His & hFc)
Cat.No: TMPY-00882
Species: Human
Expression System: HEK293 Cells
Mer Protein, Human, Recombinant
Cat.No: TMPY-04330
Species: Human
Expression System: HEK293 Cells
HGFR/c-Met Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01896
Species: Mouse
Expression System: HEK293 Cells
HER2/ERBB2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00778
Species: Human
Expression System: HEK293 Cells
VEGFR3/FLT4 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01936
Species: Mouse
Expression System: HEK293 Cells
TCPTP Protein, Human, Recombinant
Cat.No: TMPY-03484
Species: Human
Expression System: Baculovirus Insect Cells
Src Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04384
Species: Human
Expression System: Baculovirus Insect Cells
TrkA Protein, Human, Recombinant (His)
Cat.No: TMPY-01084
Species: Human
Expression System: HEK293 Cells
HGFR/c-Met Protein, Human, Recombinant (His)
Cat.No: TMPY-01296
Species: Human
Expression System: HEK293 Cells
TrkB Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02231
Species: Mouse
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02365
Species: Mouse
Expression System: HEK293 Cells
TrkB Protein, Human, Recombinant (His)
Cat.No: TMPY-00751
Species: Human
Expression System: HEK293 Cells
CD45 Protein, Human, Recombinant (aa 1-529, His)
Cat.No: TMPY-05308
Species: Human
Expression System: HEK293 Cells
CD45 Protein, Human, Recombinant (aa 26-577, His)
Cat.No: TMPY-05748
Species: Human
Expression System: HEK293 Cells
HER2/ERBB2 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02469
Species: Mouse
Expression System: HEK293 Cells
VEGFR3/FLT4 Protein, Human, Recombinant (His)
Cat.No: TMPY-00949
Species: Human
Expression System: HEK293 Cells
HER2/ERBB2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02314
Species: Mouse
Expression System: HEK293 Cells
DDR1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01289
Species: Human
Expression System: HEK293 Cells
C-ABL/ABL1 Protein, Human, Recombinant (GST)
Cat.No: TMPY-04396
Species: Human
Expression System: Baculovirus Insect Cells
Peptide YY/PYY Protein, Mouse, Recombinant (GST)
Cat.No: TMPH-02823
Species: Mouse
Expression System: E. coli
Peptide YY/PYY Protein, Human, Recombinant (GST)
Cat.No: TMPH-01852
Species: Human
Expression System: E. coli
Dtk Protein, Human, Recombinant (His)
Cat.No: TMPJ-01081
Species: Human
Expression System: HEK293 Cells
TIE2 Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-05049
Species: Rhesus
Expression System: HEK293 Cells
Dtk Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-01017
Species: Mouse
Expression System: HEK293 Cells
Dtk Protein, Mouse, Recombinant (mFc)
Cat.No: TMPJ-01018
Species: Mouse
Expression System: HEK293 Cells
TIE2 Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-02508
Species: Rat
Expression System: HEK293 Cells
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Cat. No. Product Name Target Signaling Pathways
T36384 DL-Tyrosine-13C9,15N

L-Tyrosine-13C9,15N

L-Tyrosine-13C9,15N is intended for use as an internal standard for the quantification of L-tyrosine by GC- or LC-MS. L-Tyrosine is a non-essential amino acid.1It is produced by hydroxylation of phenylalanine by phenylalanine hydroxylase but can also be obtained from dietary sources or degradation of endogenous proteins, resulting in L-tyrosine release.1,2L-Tyrosine is a precursor in the biosynthesis of catecholamine neurotransmitters, melanins, and thyroid hormones.3Plasma, skeletal muscle, and...
TMID-0106 3,3',5-Triiodothyronine-(tyrosine ring-13C6)

T3-13C6

3,3',5-Triiodothyronine-(tyrosine ring-13C6) 是 3,3',5-Triiodothyronine 的 13C 的标记化合物。3,3',5-Triiodothyronine 的 CAS 号为 5817-39-0。
TMID-0105 Triiodothyronine-13C6 hydrochloridehydrochloride

3,3',5-Triiodothyronine-(tyrosine ring-13C6)

3,3',5-Triiodothyronine-(tyrosine ring-13C6) hydrochloride 是 3,3',5-Triiodothyronine hydrochloride 的 13C 的标记化合物。
TMID-0114 3-Methoxy-L-tyrosine-d3 monohydrate

3-Methoxy-L-tyrosine-d3 monohydrate 是 3-Methoxy-L-tyrosine monohydrate 的氘代化合物。3-Methoxy-L-tyrosine monohydrate 的 CAS 号为 200630-46-2。
T10766 Ceritinib D7

LDK378 D7

Others Others
Ceritinib D7 (LDK378 D7) is a deuterium-labeled Ceritinib. Ceritinib is an ATP-competitive inhibitor of ALK tyrosine kinase.
TMIH-0610 Zanubrutinib-d5

Zanubrutinib-d5 是 Zanubrutinib 的氘代化合物。Zanubrutinib 的 CAS 号为 1691249-45-2。Zanubrutinib 是 Bruton tyrosine kinase(Btk) 的选择性抑制剂。
T10962 Dasatinib-d8

BMS-354825 D8

Others Others
Dasatinib D8 is deuterium-labeled dasatinib. Dasatinib is a dual Bcr-Abl and Src family tyrosine kinase inhibitor.
T12698 Regorafenib-d3

Regorafenib D3,BAY 73-4506 D3

Others Others
Regorafenib D3 is a deuterium labeled Regorafenib. Regorafenib is a multi-targeted receptor inhibitor of tyrosine kinase.
T11639 Imatinib D4

CGP-57148B D4,STI571 D4

Others Others
Imatinib D4 is a deuterium-labeled Imatinib. Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, PDGFR, v-Abl, and c-kit kinase activity.
T12224 Nilotinib-d6

AMN107 D6

Others Others
Nilotinib D6 is a deuterium labeled Nilotinib which is an orally available inhibitor of Bcr-Abl tyrosine kinase ,and with antineoplastic activity.
T11384 Gefitinib-d8

ZD1839 D8,Gefitinib D8

Others Others
Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells. Gefitinib D8 is a deuterium labeled Gefitinib.
T35915 Erlotinib-13C6

Erlotinib-13C6

Erlotinib-13C6 (CP-358774-13C6) is a 13C-labeled Erlotinib. Erlotinib is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR[1]. Erlotinib reduces EGFR autophosphorylation in intact tumor cells with an IC50 of 20 nM. Erlotinib is used for the treatment of non-small cell lung cancer[1].Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process[2]...
T13039 Sunitinib-d10

Sunitinib D10,SU 11248 D10

VEGFR; PDGFR Angiogenesis; Tyrosine Kinase/Adaptors
Sunitinib D10 is a deuterium labeled Sunitinib. Sunitinib is a inhibitor of multi-targeted receptor tyrosine kinase(IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively).
T11640 Imatinib-d8

CGP-57148B D8,STI571 D8

Others Others
Imatinib D8 is a deuterium-labeled Imatinib. Imatinib is an orally bioavailable tyrosine kinases inhibitor that inhibits BCR/ABL, PDGFR, v-Abl, and c-kit kinase activity.
T11229 Erlotinib-d6

OSI-774 D6,NSC 718781 D6,CP-358774 D6

Others Others
Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR. Erlotinib D6 is a deuterium labeled Erlotinib .
TMIJ-0330 Gilteritinib-d8

Gilteritinib-d8 是 Gilteritinib 的氘代化合物。Gilteritinib 的 CAS 号为 1254053-43-4。Gilteritinib 是一种 FLT3 抑制剂 (IC50:0.29 nM),也是一种 AXL 抑制剂 (IC50:0.73 nM),具有ATP 竞争性。
T19119 3-Hydroxy Midostaurin-D5

CGP52421-D5

Others Others
3-Hydroxy Midostaurin-D5 (CGP52421-D5) is a deuterium-labeled 3-Hydroxy Midostaurin which is a metabolite of PKC412. PKC412 effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation (IC50s: 132 nM and 9.8 μM in culture medium and plasma).
TMIJ-0124 Regorafenib-13C-d3

Regorafenib-13C-d3 是 Regorafenib 的 13C 和氘代化合物。Regorafenib 的 CAS 号为 755037-03-7。Regorafenib 是一种多靶点受体酪氨酸激酶抑制剂,对 RET、C-RAF、VEGFR2、c-Kit、VEGFR1和PDGFRβ 的 IC50为1.5、2.5、4.2、7、13和22 nM。
TMID-0288 Apatinib-d8

Apatinib-d8 是 Apatinib 的氘代化合物。Apatinib 的 CAS 号为 811803-05-1。Apatinib 是一种口服生物可利用的特异性 VEGFR2 抑制剂 (IC50: 1 nM)。此外,该试剂温和地抑制 c-Kit 和 c-SRC 酪氨酸激酶。
TMID-0073 Alectinib-d8

Alectinib-d8 是 Alectinib 的氘代化合物。Alectinib 的 CAS 号为 1256580-46-7。Alectinib 是一种有效的、选择性的、口服具有活力的、ATP 竞争性的ALK抑制剂,其IC50=1.9 nM,Kd=2.4 nM,并且还抑制ALK F1174L和ALK R1275Q,其IC50分别为 1 nM 和 3.5 nM。它还有中枢神经系统渗透能力。
TMIH-0393 Nintedanib-13C-d3

Nintedanib-13C-d3 是 Nintedanib 的 13C 和氘代化合物。Nintedanib 的 CAS 号为 656247-17-5。Nintedanib 是一种有效的三重血管激酶抑制剂,能够抑制VEGFR1 (IC50:34 nM)、VEGFR2 (IC50:13 nM)、VEGFR3 (IC50:13 nM),FGFR1 (IC50:69 nM)、FGFR2 (IC50:37 nM)、FGFR3 (IC50:108 nM),PDGFRα (IC50:59 nM)、PDGFRβ (IC50:65 nM)。
TMIH-0065 Acalabrutinib-d4

Acalabrutinib-d4 是 Acalabrutinib 的氘代化合物。Acalabrutinib 的 CAS 号为 1420477-60-6。Acalabrutinib 是一种不可逆的、高效的、具有口服活性、选择性的第二代BTK抑制剂。它与 BTK 的 ATP 结合口袋中的 Cys481 共价结合。它在慢性淋巴细胞性白血病 (CLL) 小鼠模型中显示出强大的靶向作用和功效。
TMIJ-0154 Lenvatinib-d4

Lenvatinib-d4 是 Lenvatinib 的氘代化合物。Lenvatinib 的 CAS 号为 417716-92-8。Lenvatinib 是一种口服具有活性的,多靶点酪氨酸激酶抑制剂,能够抑制血管内皮生长因子受体(VEGFR1-3),成纤维细胞生长因子受体(FGFR1-4),干细胞因子受体(KIT),血小板衍生生长因子受体(PDGFR),转染期间重排(RET),具有效抗癌的作用。
TMIH-0413 Osimertinib-d6

Osimertinib-d6 是 Osimertinib 的氘代化合物。Osimertinib 的 CAS 号为 1421373-65-0。Osimtinib 是一种小分子酪氨酸激酶受体抑制剂和抗肿瘤剂,用于治疗选定形式的晚期非小细胞肺癌,其有效抑制 L858R 和 L858R/T790M EGFR,IC50 为 12 和 1 nM。
TMIJ-0333 Nintedanib-d8

Nintedanib-d8 是 Nintedanib 的氘代化合物。Nintedanib 的 CAS 号为 656247-17-5。Nintedanib 是一种有效的三重血管激酶抑制剂,能够抑制VEGFR1 (IC50:34 nM)、VEGFR2 (IC50:13 nM)、VEGFR3 (IC50:13 nM),FGFR1 (IC50:69 nM)、FGFR2 (IC50:37 nM)、FGFR3 (IC50:108 nM),PDGFRα (IC50:59 nM)、PDGFRβ (IC50:65 nM)。
TMIJ-0147 Gefitinib-d6

Gefitinib-d6 是 Gefitinib 的氘代化合物。Gefitinib 的 CAS 号为 184475-35-2。Gefitinib 是一种有口服活性的EGFR酪氨酸激酶抑制剂,可诱导细胞自噬,有抗肿瘤活性。它选择性抑制 EGF 刺激的肿瘤细胞生长,并阻断 EGF 刺激的肿瘤细胞中EGFR自磷酸化。
TMIJ-0115 Crizotinib-d5

Crizotinib-d5 是 Crizotinib 的氘代化合物。Crizotinib 的 CAS 号为 877399-52-5。Crizotinib 是 c-MET 和 ALK 受体的 ATP 竞争性小分子酪氨酸激酶抑制剂,IC50为 8和20 nM。在细胞的实验中,它抑制 NPM-ALK 的酪氨酸磷酸化和 c-Met 的酪氨酸磷酸化。它也是ROS1抑制剂。它有肿瘤生长抑制作用。
TMIH-0124 Brivanib Alaninate-d4

Brivanib Alaninate-d4 是 Brivanib Alaninate 的氘代化合物。Brivanib Alaninate 的 CAS 号为 649735-63-7。Brivanib alaninate 是一种血管内皮生长因子受体 2 (VEGFR2) 抑制剂的丙氨酸盐,IC50值为 25 nM,具有潜在的抗肿瘤活性。它对 VEGFR1 和 FGFR1 适度抑制,对 VEGFR2 的选择性是对 PDGFRβ 的 240 倍。
T36055 Nitisinone-13C6

Nitisinone-13C6

Nitisinone-13C6is intended for use as an internal standard for the quantification of nitisinone by GC- or LC-MS. Nitisinone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD), which converts 4-hydroxyphenylpyruvate (HPPA) to homogentisate in the tyrosine catabolic pathway.1Nitisinone increases urinary levels of HPPA and 4-hydroxyphenyllactate (HPLA) in rats when administered at a dose of 10 mg/kg. Nitisinone (3 mg/kg) prevents the neonatal lethality of fumarylacetoacetate hydrolase (F...
TMID-0096 P-CRESOL-d3 (METHYL-d3)

P-CRESOL-d3 (METHYL-d3) 是 P-CRESOL 的氘代化合物。P-CRESOL 的 CAS 号为 106-44-5。p-Cresol 是一种部分亲脂性部分,在正常条件下与血浆蛋白(接近 100%)强烈结合。对甲酚通过结合代谢,主要是硫酸化和葡萄糖醛酸化,但未结合的对甲酚至少部分通过尿液去除。

同位素标记化合物

DL-Tyrosine-13C9,15N
Cat.No: T36384
Synonym: L-Tyrosine-13C9,15N
Target:
3,3',5-Triiodothyronine-(tyrosine ring-13C6)
Cat.No: TMID-0106
Synonym: T3-13C6
Target:
Triiodothyronine-13C6 hydrochloridehydrochloride
Cat.No: TMID-0105
Synonym: 3,3',5-Triiodothyronine-(tyrosine ring-13C6)
Target:
3-Methoxy-L-tyrosine-d3 monohydrate
Cat.No: TMID-0114
Synonym:
Target:
Ceritinib D7
Cat.No: T10766
Synonym: LDK378 D7
Target: Others
Zanubrutinib-d5
Cat.No: TMIH-0610
Synonym:
Target:
Dasatinib-d8
Cat.No: T10962
Synonym: BMS-354825 D8
Target: Others
Regorafenib-d3
Cat.No: T12698
Synonym: Regorafenib D3,BAY 73-4506 D3
Target: Others
Imatinib D4
Cat.No: T11639
Synonym: CGP-57148B D4,STI571 D4
Target: Others
Nilotinib-d6
Cat.No: T12224
Synonym: AMN107 D6
Target: Others
Gefitinib-d8
Cat.No: T11384
Synonym: ZD1839 D8,Gefitinib D8
Target: Others
Erlotinib-13C6
Cat.No: T35915
Synonym: Erlotinib-13C6
Target:
Sunitinib-d10
Cat.No: T13039
Synonym: Sunitinib D10,SU 11248 D10
Target: VEGFR, PDGFR
Imatinib-d8
Cat.No: T11640
Synonym: CGP-57148B D8,STI571 D8
Target: Others
Erlotinib-d6
Cat.No: T11229
Synonym: OSI-774 D6,NSC 718781 D6,CP-358774 D6
Target: Others
Gilteritinib-d8
Cat.No: TMIJ-0330
Synonym:
Target:
3-Hydroxy Midostaurin-D5
Cat.No: T19119
Synonym: CGP52421-D5
Target: Others
Regorafenib-13C-d3
Cat.No: TMIJ-0124
Synonym:
Target:
Apatinib-d8
Cat.No: TMID-0288
Synonym:
Target:
Alectinib-d8
Cat.No: TMID-0073
Synonym:
Target:
Nintedanib-13C-d3
Cat.No: TMIH-0393
Synonym:
Target:
Acalabrutinib-d4
Cat.No: TMIH-0065
Synonym:
Target:
Lenvatinib-d4
Cat.No: TMIJ-0154
Synonym:
Target:
Osimertinib-d6
Cat.No: TMIH-0413
Synonym:
Target:
Nintedanib-d8
Cat.No: TMIJ-0333
Synonym:
Target:
Gefitinib-d6
Cat.No: TMIJ-0147
Synonym:
Target:
Crizotinib-d5
Cat.No: TMIJ-0115
Synonym:
Target:
Brivanib Alaninate-d4
Cat.No: TMIH-0124
Synonym:
Target:
Nitisinone-13C6
Cat.No: T36055
Synonym: Nitisinone-13C6
Target:
P-CRESOL-d3 (METHYL-d3)
Cat.No: TMID-0096
Synonym:
Target:
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