Lck inhibitor 2

Name: Lck inhibitor 2
Brand: TargetMol
SKU: T15725
Price: 195 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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产品编号 T15725Cas号 944795-06-6

Lck inhibitor 2 is a bis-anilinopyrimidine inhibitor of tyrosine kinases including LCK, BTK, LYN, SYK, and TXK (IC50s: 13nM, 9nM, 3nM, 26nM, and 2nM for Lck, Btk, Lyn, Btk, and Txk respectively).

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Lck inhibitor 2

还可以

产品编号 T15725Cas号 944795-06-6

Lck inhibitor 2 is a bis-anilinopyrimidine inhibitor of tyrosine kinases including LCK, BTK, LYN, SYK, and TXK (IC50s: 13nM, 9nM, 3nM, 26nM, and 2nM for Lck, Btk, Lyn, Btk, and Txk respectively).

规格	价格	库存
2 mg	¥ 720	5日内发货
5 mg	¥ 1,230	5日内发货
25 mg	¥ 4,350	6-8周
50 mg	¥ 5,660	6-8周
100 mg	¥ 7,890	6-8周
1 mL x 10 mM (in DMSO)	¥ 1,370	5日内发货

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产品介绍

生物活性

产品描述	Lck inhibitor 2 is a bis-anilinopyrimidine inhibitor of tyrosine kinases including LCK, BTK, LYN, SYK, and TXK (IC50s: 13nM, 9nM, 3nM, 26nM, and 2nM for Lck, Btk, Lyn, Btk, and Txk respectively).
体外活性	A further 27 kinases were bound with %control < 10. Kd values for 16 kinases were determined and found to be below 100 nM. These included TXK (10 nM). Src family kinase Lck inhibitor 2 inhibited 48 kinases with %control < 1 (33 of them tyrosine kinases, almost half of the 71 tyrosine kinases in the panel) [2].

化学信息

分子量	335.36
分子式	C₁₈H₁₇N₅O₂
CAS No.	944795-06-6
密度	1.389 g/cm3 (Predicted)

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

溶解度信息

DMSO: 20 mg/mL (59.64 mM), Sonication is recommended.

溶液配制表

	1mg	5mg	10mg	50mg
1 mM	2.9819 mL	14.9094 mL	29.8187 mL	149.0935 mL
5 mM	0.5964 mL	2.9819 mL	5.9637 mL	29.8187 mL
10 mM	0.2982 mL	1.4909 mL	2.9819 mL	14.9094 mL
20 mM	0.1491 mL	0.7455 mL	1.4909 mL	7.4547 mL
50 mM	0.0596 mL	0.2982 mL	0.5964 mL	2.9819 mL