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LDN-192960 hydrochloride
还可以产品编号 T11830Cas号 2309172-48-1
LDN-192960 hydrochloride is an inhibitor of Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) and Haspin with IC50s of 48 nM and 10 nM, respectively.
LDN-192960 hydrochloride
还可以产品编号 T11830Cas号 2309172-48-1
LDN-192960 hydrochloride is an inhibitor of Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) and Haspin with IC50s of 48 nM and 10 nM, respectively.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 mg | ¥ 7,840 | 1-2周 | |
| 50 mg | ¥ 10,400 | 1-2周 | |
| 100 mg | ¥ 16,200 | 1-2周 |
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| 产品描述 | LDN-192960 hydrochloride is an inhibitor of Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) and Haspin with IC50s of 48 nM and 10 nM, respectively. |
| 靶点活性 | DYRK2:48 nM , Haspin:10 nM |
| 体外活性 | LDN-192960 hydrochloride (10 μM) is inhibits ten of the other kinases by ≥90%, with only five being potently inhibited (IC50<1 μM), including CLK1 (IC50=0.21 μM), DYRK1A (IC50= 0.10 μM), DYRK2 (IC50=2 nM), DYRK3 (IC50=19 nM) and PIM1 (IC50=0.72 μM)[1]. |
| 分子量 | 401.35 |
| 分子式 | C18H22Cl2N2O2S |
| CAS No. | 2309172-48-1 |
| 密度 | no data available |
储存&溶解度
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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