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Targets Recommended: Epigenetic Reader Domain Others

470

抑制剂 & 化合物

71

天然产物

18

化合物库

1

TargetMol 试剂盒

785

重组蛋白

10

同位素标记化合物

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Cat. No. Product Name
L1200 表观遗传库

953 compounds
953 种表观遗传学研究相关的生物活性小分子的特有集合,用于表观遗传学研究及其相关的检测和高通量、高内涵筛选;
L7700 神经再生化合物库

524 compounds
524 种神经再生相关化合物的独特集合,可用于高通量筛选和高内涵筛选;
L7900 成骨分子库

317 compounds
317 种成骨相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
BN1100 二代高端片段化合物库

1139 compounds
The 2nd Generation Premium Fragment Library contains 1166 compounds.
L4800 血管生成库

1353 compounds
1353 个高潜力的抑制或促进血管生成的小分子集合,可用于药物靶点开发、血管生成机理研究的高通量筛选,高内涵筛选;
L2620 神经退行性疾病化合物库

2154 compounds
2154 种与神经退行性疾病相关的化合物,可用于高通量和高内涵筛选;
L3510 甲基化化合物库

128 compounds
128 种甲基化相关的化合物,可以用于高通量和高内涵筛选;
L3800 NF-κB 通路分子库

729 compounds
729 个 NF-κB 信号通路相关的小分子化合物的特有集合,用于高通量、高内涵筛选;
L6001 Mini真菌代谢天然产物筛选库

Inquiry
L3500 组蛋白修饰化合物库

469 compounds
469 个组蛋白修饰相关的小分子化合物的特有集合,用于高通量、高内涵筛选;
L3600 细胞因子抑制剂库

604 compounds
604 个与细胞因子紧密相关的化合物集合,是高通量、高内涵筛选的良好载体;
L5400 抗心血管疾病化合物库

1408 compounds
1408 种心血管疾病相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L8200 抗衰老化合物库

3279 compounds
3279 个抗衰老化合物的独特集合,可用于高通量筛选和高内涵筛选;
L8300 染色质修饰分子库

250 compounds
250 种染色质化学修饰相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L2140 癌细胞分化化合物库

406 compounds
406 个诱导肿瘤细胞分化化合物的独特集合,可用于高通量筛选和高内涵筛选;
L7200 钙通道分子库

140 compounds
140 种钙通道相关化合物的独特集合,可用于高通量筛选和高内涵筛选;
L9500 表型筛选靶点鉴定库

1796 compounds
1796 种靶点明确的已知活性化合物,适合表型筛选;
L8500 HIF-1化合物库

1336 compounds
1336 个HIF-1相关小分子的独特集合,可用于缺血性疾病、癌症等相关领域的药物开发和药理研究;

化合物库

表观遗传库
Cat.No: L1200
Compounds: 953
神经再生化合物库
Cat.No: L7700
Compounds: 524
成骨分子库
Cat.No: L7900
Compounds: 317
二代高端片段化合物库
Cat.No: BN1100
Compounds: 1139
血管生成库
Cat.No: L4800
Compounds: 1353
神经退行性疾病化合物库
Cat.No: L2620
Compounds: 2154
甲基化化合物库
Cat.No: L3510
Compounds: 128
NF-κB 通路分子库
Cat.No: L3800
Compounds: 729
Mini真菌代谢天然产物筛选库
Cat.No: L6001
Compounds: Inquiry
组蛋白修饰化合物库
Cat.No: L3500
Compounds: 469
细胞因子抑制剂库
Cat.No: L3600
Compounds: 604
抗心血管疾病化合物库
Cat.No: L5400
Compounds: 1408
抗衰老化合物库
Cat.No: L8200
Compounds: 3279
染色质修饰分子库
Cat.No: L8300
Compounds: 250
癌细胞分化化合物库
Cat.No: L2140
Compounds: 406
钙通道分子库
Cat.No: L7200
Compounds: 140
表型筛选靶点鉴定库
Cat.No: L9500
Compounds: 1796
HIF-1化合物库
Cat.No: L8500
Compounds: 1336
Cat. No. Product Name Form Specificity Of Inhibition
C0048 Deacetylase Inhibitor Cocktail (100× in 70% DMSO)

去乙酰化酶抑制剂 Cocktail(100× in 70% DMSO)

Solution (100× in 70% DMSO) Class I/II/III HDAC

TargetMol 试剂盒

去乙酰化酶抑制剂 Cocktail(100× in 70% DMSO)
Cat.No: C0048
Cat. No. Product Name Target Signaling Pathways
TP1200 CGRP (83-119), rat TFA

Calcitonin Gene Related Peptide(83-119), rat TFA

Others Others
CGRP (83-119), rat TFA (Calcitonin Gene Related Peptide(83-119), rat TFA) 是一种由 37 个氨基酸组成的神经肽降钙素家族,通过降钙素受体样受体起作用。
TP1202 Calcitonin Gene Related Peptide (CGRP) II, rat

CGRP II, rat

Calcitonin Gene Related Peptide II is a potent, long-lasting vasodilator; activation of CGRP receptors on pancreatic β-cells increases plasma levels of pancreatic enzymes.
T76032 Calcitonin Gene Related Peptide (CGRP) II, rat TFA

CalcitoninGene Related Peptide (CGRP) II, rat TFA,为CGRP受体激活剂,具有显著且持久的血管扩张效果,适用于心血管疾病研究。
TP2465 PHYD protein, Arabidopsis

Phyd gene product,Phyd protein

PHYD protein, Arabidopsis belongs to the phytochrome apoprotein family in Arabidopsis.
T76363 [Tyr22] Calcitonin Gene Related Peptide, (22-37), rat

[Tyr22]CalcitoninGene Related Peptide, (22-37), rat 是一种大鼠降钙素基因相关肽 (CGRP) 的 22-37 片段,靶向CGRP 受体和腺苷酸环化酶。降钙素 (calcitonin) 主要由甲状腺 C 细胞产生,而 CGRP 则分泌并储存在神经系统中。
TP1203 CGRP(83-119), rat

Calcitonin Gene Related Peptide (CGRP) (83-119), rat

Calcitonin Gene Related Peptide (CGRP) (83-119), rat is a 37 amino acid calcitonin family of neuropeptide, acts through calcitonin receptor-like receptor.
TP1201 CGRP II, rat (TFA) (99889-63-1 free base)

Calcitonin Gene Related Peptide (CGRP) II, rat (TFA),CGRP II, rat (TFA)

Calcitonin Gene Related Peptide (CGRP) II, rat (TFA) is a neuropeptide with 37 amino acid.
T17194 Ubrogepant

MK-1602

CGRP Receptor GPCR/G Protein; Neuroscience
Ubrogepant (MK-1602) 是新型的、口服有效的降钙素基因相关肽受体拮抗剂。Ubrogepant 有潜力用于急性偏头痛的相关研究。
T9266 Fatostatin

Lipid; Fatty Acid Synthase Metabolism
Fatostatin A 是一种SREBP 活化的特异性抑制剂,能够抑制 SREBP-1 和 SREBP-2 的活化。它与 SCAP (SREBP 裂解激活蛋白) 结合,抑制 SREBPs 的 ER-Golgi 易位。它具有抗肿瘤活性,能抑制ob/ob 小鼠的高血糖。它抑制细胞中成脂基因的转录。
T9216 MLT-943

MLT943

MALT Immunology/Inflammation
ML-943 是选择性的、口服活性的MALT1 protease 抑制剂。它可抑制 PBMC 或全血中 IL-2 的分泌,PBMC 中抑制的IC50值为 0.07~0.09 μM,全血中抑制的IC50值为 0.6~0.8 μM)。它具有抗炎作用,可用于研究 FcgR 介导的炎症。
T36670 JNJ-67856633

MALT Immunology/Inflammation
JNJ-67856633 是口服有效的、选择性的、变构性的 MALT1 protease 抑制剂。在某些情况下,JNJ-67856633可以导致肿瘤停滞。
TP1040 Calcitonin (salmon)

鲑降钙素,Calcitonin salmon,Salmon calcitonin

CGRP Receptor GPCR/G Protein; Neuroscience
Calcitonin (salmon) 是一种阿米林和卡西宁受体的双激动剂,是一种钙调节激素,能够刺激骨的生成并能抑制骨吸收。
T16040 Mepazine

甲哌啶嗪,Pecazine

Apoptosis; MALT Apoptosis; Immunology/Inflammation
Mepazine (Pecazine) 是一种有效的特异性 MALT1 抑制剂。 Mepazine 抑制 GSTMALT1 全长和 GSTMALT1 325-760,IC50 为 0.83 μM 和 0.42 μM。 Mepazine 增强细胞凋亡并影响细胞活力。
T12293L Olcegepant

BIBN-4096,BIBN 4096BS

CGRP Receptor GPCR/G Protein; Neuroscience
Olcegepant (BIBN-4096) 是一种选择性的降钙素基因相关肽1 (CGRP1) 受体拮抗剂,IC50=0.03 nM,Ki=14.4 pM。
T4610 Rimegepant

BMS 927711,BMS-927711,BMS927711,BHV-3000

CGRP Receptor GPCR/G Protein; Neuroscience
Rimegepant (BMS 927711) 是一种有效的降钙素基因相关肽 (CGRP) 受体拮抗剂 (Ki=0.027 nM,IC50=0.14 nM)。Rimegepant 可同时用于偏头痛急性发作治疗及预防性治疗。
T23383 SR11237

SR 11237

Others; RAR/RXR  Metabolism; Others
SR11237 是一种泛视黄醇 X 受体 (RXR) 激动剂。 SR11237 导致 RXR/RXR 同源二聚体形成并反式激活包含 RXR 反应元件的报告基因。
T8682 Vazegepant hydrochloride

Vazegepant HCl

CGRP Receptor GPCR/G Protein; Neuroscience
Vazegepant hydrochloride (Vazegepant HCl) 是一种用于偏头痛的鼻用 gepant,是一种高度亲和性CGRP 受体拮抗剂 (hCGRPKi=0.023 nM)。它可能有助于有效管理 COVID-19 相关肺部炎症。
T1724 SCR7 pyrazine

SCR7,SCR7 吡嗪

Apoptosis; DNA/RNA Synthesis; CRISPR/Cas9 Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
SCR7 pyrazine (SCR7) 是一种 DNA 连接酶 IV 抑制剂,以连接酶 IV 依赖的方式阻断非同源末端连接。它也是 CRISPR/Cas9的增强子,可提高 Cas9 介导的同源性定向修复的效率。它诱导细胞凋亡,具有抗癌活性。
T4641 Branaplam

LMI 070,NVS-SM1

Others; Potassium Channel; DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Others
Branaplam (LMI 070) 是一种高效、选择性和口服活性的小分子 SMN2 剪接调节剂,对 SMN 的 EC50为 20 nM。它可提高全长 SMN 蛋白并延长其生存期,也抑制 hERG,IC50为 6.3 μM。
T1676 Rosuvastatin

罗伐他汀,ZD 4522,瑞舒伐他汀

Potassium Channel; HMG-CoA Reductase; Autophagy Autophagy; Membrane transporter/Ion channel; Metabolism
Rosuvastatin (ZD 4522) 是一种抗血脂药,可竞争性抑制羟甲基戊二酰辅酶 A 还原酶,用于降低血浆胆固醇水平和预防心血管疾病。它降低低密度脂蛋白胆固醇、甘油三酯和 C-反应蛋白水平。它阻断人类醚-a-go-go 相关基因电流,IC50为 195 nM,延迟心脏复极化,延长动作电位持续时间和校正 QT 间期间隔。
T6832 Fatostatin hydrobromide

Fatostatin HBr,Fatostatin A,Fatostatin A HBr,Fatostatin

NPC1L1; Fatty Acid Synthase Membrane transporter/Ion channel; Metabolism
Fatostatin hydrobromide (Fatostatin A HBr) 是一种 SREBP 活化的特异性抑制剂,可抑制 SREBP-1 和 SREBP-2 的活化。它与 SCAP (SREBP 裂解激活蛋白) 结合,抑制 SREBPs 的 ER-Golgi 易位。它具有抗肿瘤作用,能抑制 ob/ob 小鼠的高血糖。它抑制了细胞中成脂基因的转录。
T1692 3-(3,4-Dimethoxyphenyl)propanoic acid

3,4-Dimethoxyhydrocinnamic acid,3,4-二甲氧基苯丙酸,3-(3,4-二甲氧基苯)丙酸

Aromatase Endocrinology/Hormones
3-(3,4-Dimethoxyphenyl)propanoic acid (3,4-Dimethoxyhydrocinnamic acid) 是一种口服具有活力的的短链脂肪酸 (SCFAs)。它在体内能够促进 γ 球蛋白基因表达和促红细胞生成,可用于 β 血红蛋白病和其他贫血症。
T2350 MALT1 inhibitor MI-2

MALT1 inhibitor,MI 2,MI 2 (MALT1 inhibitor)

MALT Immunology/Inflammation
MI 2 (MALT1 inhibitor) 是一种MALT1抑制剂 (IC50=5.84 μM),对动物无毒性。它能够直接与 MALT1 结合,不可逆地抑制蛋白酶功能,并伴有 NF-κB 报告子活性抑制、c-REL 核定位抑制和 NF-κB 靶基因下调。
T5045 GSK4112

1,1-Dimethylethyl-N-[(4-chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl])glycinate,SR6452

Autophagy Autophagy
GSK4112 (SR6452) 是一种 Rev-erbα 激动剂,EC50 为 0.4 μM。它也是一种用于核血红素受体 Rev-erbα 的细胞生物学的小分子化学探针。
T1826 PI3K-IN-1

Voxtalisib Analogue,Voxtalisib (SAR245409, XL765) Analogue,XL765,SAR245409

DNA-PK; PI3K DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
PI3K-IN-1 (Voxtalisib Analogue) 是 PI3K 抑制剂,PI3K-IN-1(25 μM) 能够阻断 PI3K/Akt 信号通路。
T1510 Rosuvastatin calcium

ZD 4522 Calcium,ZD4522,Rosuvastatin hemicalcium,瑞舒伐他汀钙

Potassium Channel; HMG-CoA Reductase; Autophagy Autophagy; Membrane transporter/Ion channel; Metabolism
Rosuvastatin calcium (ZD4522) 是肝羟甲基戊二酰辅酶 A 还原酶的选择性和竞争性抑制剂,具有抗血脂活性。它降低成熟 hERG 的表达以及热休克蛋白 70 与 hERG 蛋白的相互作用,还降低低密度脂蛋白胆固醇、甘油三酯和 C-反应蛋白水平。它阻断人类醚-a-go-go 相关基因电流,延迟心脏复极化,来延长动作电位持续时间和校正 QT 间期间隔。
T3340 SCR7

Apoptosis; DNA/RNA Synthesis; CRISPR/Cas9 Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
SCR7 是一种特异性 DNA 连接酶 IV 抑制剂,可阻断非同源末端连接。它是一种不稳定的形式,可以自动循环成​​稳定形式的 SCR7 pyrazine。它也是CRISPR/Cas9的增强子,可提高 Cas9 介导的同源性定向修复的效率。它诱导细胞凋亡并具有抗癌活性。
T6590 MK-3207 Hydrochloride

MK-3207 HCl

CGRP Receptor GPCR/G Protein; Neuroscience
MK-3207 Hydrochloride (MK-3207 HCl) 是口服具有活力的CGRP receptor 拮抗剂,IC50=0.12 nM,Ki=0.024 nM。
T77762 ROS-generating agent 1

Apoptosis; Ferroptosis; ROS Kinase Apoptosis; Tyrosine Kinase/Adaptors
ROS-generating agent 1 具有抗癌活性,通过共价修饰 TrxR 的 Sec-498 残基以生成 ROS。ROS-generating agent 1 降低细胞内 TrxR 蛋白水平,促进 NCI-H460 细胞中 ROS 依赖的性细胞凋亡 (apoptosis) 和铁死亡 (ferroptosis)。
T23535L Xanthine amine congener trihydrochloride

Xanthine amine congener trihydrochloride (96865-92-8 Free base)

Adenosine Receptor GPCR/G Protein; Neuroscience
Xanthine amine congener trihydrochloride 是一种有效的腺苷拮抗剂,可逆转由腺苷激动剂 N6-环己基腺苷产生的尿流量、钠排泄和心率的减少。
T7683 Adenosine amine congener

ADAC

Adenosine Receptor GPCR/G Protein; Neuroscience
Adenosine amine congener (ADAC) 是一种选择性的 A1 腺苷受体激动剂,具有神经保护作用,可以改善噪音和顺铂引起的耳蜗损伤。
T74217 Angiogenesis agent 1

HIF/HIF Prolyl-Hydroxylase Chromatin/Epigenetic; Metabolism
Angiogenesis agent 1 (compound C-31) 为红景天苷衍生的糖苷类似物,能激活 HIF-1α 通路。该化合物有助于研究糖尿病所致后肢缺血。
T23535 Xanthine amine congener

Adenosine Receptor GPCR/G Protein; Neuroscience
Xanthine amine congener 是非选择性的腺苷受体拮抗剂,在小鼠中具有诱发惊厥的作用。
T72013 Epigenetic Multiple Ligand

Others Others
Epigenetic Multiple Ligand is a cell-permeable inhibitor of substrate processing by several chromatin-associated enzymes, including SIRT1/2, H3/SET7, H3/p300/CBP, H4/RmtA, PABP1/CARM1, and H4/PRMT1. It acts by inducing either apoptosis or granulocytic differentiation.
T74627 Angiogenesis inhibitor 3

Others Others
Angiogenesis inhibitor 3 (compound 8) 是一种有效的血管生成(angiogenesis)抑制剂,能够抑制HUVEC和HCT-15细胞增殖,其IC50值分别为1.00和0.71 μM。此外,此化合物还能诱导这两种细胞的凋亡(apoptosis)并具有抑制癌细胞侵袭的抗癌活性。Angiogenesis inhibitor 3还能够抑制斑马鱼胚胎的血管生成。
T10122 Anti-neurodegeneration agent 1

Others Others
Anti-neurodegeneration agent 1 a neurodegeneration-targeting agent.
T75270 Genevant CL1

Others Others
Genevant CL1 是一种脂质,可用于 mRNA 脂质纳米颗粒 (LNP) 疫苗递送。
T62963 Xanthine amine congener hydrochloride

Others Others
Xanthine amine congener (XAC) hydrochloride 是一种非选择性腺苷受体拮抗剂,在小鼠中能够诱发惊厥。
T71722 Angiogenesis inhibitor BT2

Others Others
Angiogenesis inhibitor BT2 is a novel inhibitor of angiogenesis and vascular permeability, inhibiting ERK phosphorylation and the expression of FosB/ΔFosB, VCAM-1, and many genes involved in proliferation, migration, angiogenesis, and inflammation, interacting with MEK1, suppressing retinal CD31, pERK, VCAM-1, and VEGF-A165 expression.
T39387 Xanthine amine congener dihydrochloride

XAC dihydrochloride,Xanthine amine congener dihydrochloride

Others Others
Xanthine amine congener dihydrochloride (XAC dihydrochloride), a potent antagonist for both Adenosine A1 and A2 receptors, exhibits IC50 values of 1.8 nM for A1 and 114 nM for A2 receptors. Additionally, it functions as a convulsant agent in mouse models.
T83527 (Rac)-Neurodegenerative Disorder-Targeting Compound 1

Others Others
(Rac)-Neurodegenerative Disorder-Targeting Compound 1为一种针对神经退行性疾病的化合物,具有calpain抑制活性。
T82458 Epigenetic factor-IN-1

Sirtuin Chromatin/Epigenetic; DNA Damage/DNA Repair
Epigenetic factor-IN-1(40569Z)是一种针对SIRT7显示出强效结合能力的表观遗传因子抑制剂,常用于肝癌的研究领域。
T76164 Lipoxygenase, general

Lipoxygenase, general (LOX) 是一种在生化研究中常用的双加氧酶,它能催化如亚油酸和花生四烯酸等多不饱和脂肪酸,生成相应的氢过氧化物。
T13486 Neurodegenerative Disorder-Targeting Compound 1

Others Others
Neurodegenerative Disorder-Targeting Compound 1 是一种靶向 calpain 的抑制剂。
T83116 Angiogenesis inhibitor 4

Others Others
Angiogenesis Inhibitor 4为一种高效血管生成抑制剂,主要应用于癌症研究领域。
T31425 Dibenz[a,h]anthracene

CCRIS 208,二苯葸,NSC 22433,AI3-18996,DB(a,h)A

DNA DNA Damage/DNA Repair
Dibenz[a,h]anthracene (CCRIS 208) 诱导细菌DNA 损伤和基因突变,并在几种哺乳动物细胞培养物中诱导基因突变和转化。
T24573 Ovatodiolide

Others Others
Ovatodiolide is a broad anticancer agent that acts by upregulating hsa-miR-155, suppressing the BCR-ABL fusion gene, and dysregulating the PI3K/AKT/mTOR pathway.
T6696 Tazarotene

他扎罗汀,Tazorac,AGN 190168,Zorac

Retinoid Receptor; Autophagy Autophagy; Metabolism
Tazarotene (Zorac) 是一种选择性视黄酸受体激动剂,用于研究寻常痤疮和斑块状银屑病。
T39965 NF-κΒ activator 1

NF-κB NF-κB
NF-κΒ activator 1 可激活NF-κΒ基因,EC50 为 0.9 μM。NF-κB 作为一种调控细胞增殖和细胞存活的基因被真核细胞广泛应用。NF-κΒ activator 1 可诱导超氧化物歧化酶 (SOD)2 mRNA 表达。
T67839 HG106

Others Others
HG106具有抗炎作用,可用于治疗由 RAS 基因突变引起的各种恶性肿瘤等疾病的生长。

化合物

CGRP (83-119), rat TFA
Cat.No: TP1200
Synonym: Calcitonin Gene Related Peptide(83-119), rat TFA
Target: Others
Calcitonin Gene Related Peptide (CGRP) II, rat
Cat.No: TP1202
Synonym: CGRP II, rat
Target:
Calcitonin Gene Related Peptide (CGRP) II, rat TFA
Cat.No: T76032
Synonym:
Target:
PHYD protein, Arabidopsis
Cat.No: TP2465
Synonym: Phyd gene product,Phyd protein
Target:
[Tyr22] Calcitonin Gene Related Peptide, (22-37), rat
Cat.No: T76363
Synonym:
Target:
CGRP(83-119), rat
Cat.No: TP1203
Synonym: Calcitonin Gene Related Peptide (CGRP) (83-119), rat
Target:
CGRP II, rat (TFA) (99889-63-1 free base)
Cat.No: TP1201
Synonym: Calcitonin Gene Related Peptide (CGRP) II, rat (TFA),CGRP II, rat (TFA)
Target:
Ubrogepant
Cat.No: T17194
Synonym: MK-1602
Target: CGRP Receptor
Fatostatin
Cat.No: T9266
Synonym:
Target: Lipid, Fatty Acid Synthase
MLT-943
Cat.No: T9216
Synonym: MLT943
Target: MALT
JNJ-67856633
Cat.No: T36670
Synonym:
Target: MALT
Calcitonin (salmon)
Cat.No: TP1040
Synonym: 鲑降钙素,Calcitonin salmon,Salmon calcitonin
Target: CGRP Receptor
Mepazine
Cat.No: T16040
Synonym: 甲哌啶嗪,Pecazine
Target: Apoptosis, MALT
Olcegepant
Cat.No: T12293L
Synonym: BIBN-4096,BIBN 4096BS
Target: CGRP Receptor
Rimegepant
Cat.No: T4610
Synonym: BMS 927711,BMS-927711,BMS927711,BHV-3000
Target: CGRP Receptor
SR11237
Cat.No: T23383
Synonym: SR 11237
Target: Others, RAR/RXR 
Vazegepant hydrochloride
Cat.No: T8682
Synonym: Vazegepant HCl
Target: CGRP Receptor
SCR7 pyrazine
Cat.No: T1724
Synonym: SCR7,SCR7 吡嗪
Target: Apoptosis, DNA/RNA Synthesis, CRISPR/Cas9
Branaplam
Cat.No: T4641
Synonym: LMI 070,NVS-SM1
Target: Others, Potassium Channel, DNA/RNA Synthesis
Rosuvastatin
Cat.No: T1676
Synonym: 罗伐他汀,ZD 4522,瑞舒伐他汀
Target: Potassium Channel, HMG-CoA Reductase, Autophagy
Fatostatin hydrobromide
Cat.No: T6832
Synonym: Fatostatin HBr,Fatostatin A,Fatostatin A HBr,Fatostatin
Target: NPC1L1, Fatty Acid Synthase
3-(3,4-Dimethoxyphenyl)propanoic acid
Cat.No: T1692
Synonym: 3,4-Dimethoxyhydrocinnamic acid,3,4-二甲氧基苯丙酸,3-(3,4-二甲氧基苯)丙酸
Target: Aromatase
MALT1 inhibitor MI-2
Cat.No: T2350
Synonym: MALT1 inhibitor,MI 2,MI 2 (MALT1 inhibitor)
Target: MALT
GSK4112
Cat.No: T5045
Synonym: 1,1-Dimethylethyl-N-[(4-chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl])glycinate,SR6452
Target: Autophagy
PI3K-IN-1
Cat.No: T1826
Synonym: Voxtalisib Analogue,Voxtalisib (SAR245409, XL765) Analogue,XL765,SAR245409
Target: DNA-PK, PI3K
Rosuvastatin calcium
Cat.No: T1510
Synonym: ZD 4522 Calcium,ZD4522,Rosuvastatin hemicalcium,瑞舒伐他汀钙
Target: Potassium Channel, HMG-CoA Reductase, Autophagy
SCR7
Cat.No: T3340
Synonym:
Target: Apoptosis, DNA/RNA Synthesis, CRISPR/Cas9
MK-3207 Hydrochloride
Cat.No: T6590
Synonym: MK-3207 HCl
Target: CGRP Receptor
ROS-generating agent 1
Cat.No: T77762
Synonym:
Target: Apoptosis, Ferroptosis, ROS Kinase
Xanthine amine congener trihydrochloride
Cat.No: T23535L
Synonym: Xanthine amine congener trihydrochloride (96865-92-8 Free base)
Target: Adenosine Receptor
Adenosine amine congener
Cat.No: T7683
Synonym: ADAC
Target: Adenosine Receptor
Angiogenesis agent 1
Cat.No: T74217
Synonym:
Target: HIF/HIF Prolyl-Hydroxylase
Xanthine amine congener
Cat.No: T23535
Synonym:
Target: Adenosine Receptor
Epigenetic Multiple Ligand
Cat.No: T72013
Synonym:
Target: Others
Angiogenesis inhibitor 3
Cat.No: T74627
Synonym:
Target: Others
Anti-neurodegeneration agent 1
Cat.No: T10122
Synonym:
Target: Others
Genevant CL1
Cat.No: T75270
Synonym:
Target: Others
Xanthine amine congener hydrochloride
Cat.No: T62963
Synonym:
Target: Others
Angiogenesis inhibitor BT2
Cat.No: T71722
Synonym:
Target: Others
Xanthine amine congener dihydrochloride
Cat.No: T39387
Synonym: XAC dihydrochloride,Xanthine amine congener dihydrochloride
Target: Others
(Rac)-Neurodegenerative Disorder-Targeting Compound 1
Cat.No: T83527
Synonym:
Target: Others
Epigenetic factor-IN-1
Cat.No: T82458
Synonym:
Target: Sirtuin
Lipoxygenase, general
Cat.No: T76164
Synonym:
Target:
Neurodegenerative Disorder-Targeting Compound 1
Cat.No: T13486
Synonym:
Target: Others
Angiogenesis inhibitor 4
Cat.No: T83116
Synonym:
Target: Others
Dibenz[a,h]anthracene
Cat.No: T31425
Synonym: CCRIS 208,二苯葸,NSC 22433,AI3-18996,DB(a,h)A
Target: DNA
Ovatodiolide
Cat.No: T24573
Synonym:
Target: Others
Tazarotene
Cat.No: T6696
Synonym: 他扎罗汀,Tazorac,AGN 190168,Zorac
Target: Retinoid Receptor, Autophagy
NF-κΒ activator 1
Cat.No: T39965
Synonym:
Target: NF-κB
HG106
Cat.No: T67839
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T21205 Ponasterone A

坡那甾酮A,AI3-44686

Others Others
Ponasterone A 是一种蜕皮激素,能够高度亲和蜕皮激素受体。它能够使报告基因能够快速打开和关闭,是细胞和转基因动物中基因表达的有效调节剂。
T1426 Pyrazinamide

Pyrazinoic acid amide,Pyrazinecarboxamide,吡嗪酰胺

Antibacterial; Antibiotic; Autophagy; Fatty Acid Synthase Autophagy; Metabolism; Microbiology/Virology
Pyrazinamide (Pyrazinecarboxamide) 是一种口服抗结核类抗生素。它是一种前药,通过结核分枝杆菌pncA 基因编码的 PZase/烟酰胺酶转化为活性吡嗪酸形式。
TN1653 Fustin

ERK; Beta Amyloid; AChR MAPK; Neuroscience
Fustin 是植物漆树 (Rhus verniciflua Stokes) 的植物性黄烷醇成分。 Fustin 对 6-羟基多巴胺诱导的神经元细胞死亡具有保护作用。
T24729 Roseoflavin

Antibacterial Microbiology/Virology
Roseoflavin 是天然色素,起初分离自Streptomyces davawensis。Roseoflavin 是核黄素和黄素单核苷酸的抗代谢类似物,显示出抗菌活性。
T3919 Ginsenoside Rb2

Ginsenoside C,人参皂苷 Rb2,人参皂苷Rb2

GPR; Others; Influenza Virus; Endogenous Metabolite Endocrinology/Hormones; GPCR/G Protein; Metabolism; Microbiology/Virology; Others
Ginsenoside Rb2 (Ginsenoside C) 是人参提取物中的一种主要生物活性成分,具有抗病毒活性,可上调 GPR120 基因表达。
T4461 3,5-Diiodo-L-thyronine

3,5-二碘-L-甲状腺素,Diiodothyronine

Thyroid hormone receptor(THR); Endogenous Metabolite Endocrinology/Hormones; Metabolism
3,5-Diiodo-L-thyronine (Diiodothyronine) 是内源性代谢产物的一种。
T6S0325 Glycitein

黄豆黄素,Glycetein

Apoptosis; Others Apoptosis; Others
Glycitein (Glycetein) 是一种大豆异黄酮,可研究抗氧化和细胞凋亡。
T6S0214 dl-Maackiain

(+)-Maackiain,高丽槐素,Demethylpterocarpin

Apoptosis; Parasite Apoptosis; Microbiology/Virology
dl-Maackiain (Demethylpterocarpin) 是分离自Maackia amurensis Rupr.et Maxim 的一种杀幼虫剂,针对埃及伊蚊,其LD50为 21.95 μg/ ml。
TJS0405 Lucidin

NSC 30546,芦西定;卢西定,卢西定,亮黄素,Henine

Others Others
Lucidin (NSC-30546) 是茜草中的一种天然成分,可以诱导细菌和哺乳动物细胞的突变。
T3406 Kuromanin chloride

Glucocyanidin chloride,Chrysontemin,矢车菊素-3-O-葡萄糖苷,Chrysontemin chloride,Cyanidin 3-O-glucoside chloride

NF-κB NF-κB
Kuromanin chloride (Chrysontemin chloride) 是从桑叶中获得,能够提高血糖浓度、维持脂质代谢平衡,表现出降低肥胖的作用。
T3524 Halofuginone hydrobromide

卤夫酮溴氢酸盐,Tempostatin,RU-19110 (hydrobromide),Stenorol,常山酮溴酸盐

Others; Calcium Channel; DNA/RNA Synthesis; Sodium Channel; Parasite; TGF-beta/Smad Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Others; Stem Cells
Halofuginone hydrobromid 是Febrifugine 的衍生物,是竞争性脯氨酰-tRNA 合成酶抑制剂。它是 I 型胶原合成的特异性抑制剂,并通过抑制TGF-β活性可减轻骨关节炎。它具有抗疟疾、抗炎、抗癌、抗纤维化作用。
T19237 Cholesteryl oleate

胆固醇油酸酯,Oleoylcholesterol,Cholesterol Oleate,Cholesteryl cis-9-octadecenoate

Endogenous Metabolite Metabolism
Cholesteryl oleate (Cholesteryl cis-9-octadecenoate) 是胆固醇的酯化形式,可用于合成固体脂质纳米颗粒。
TN7236 Cephalandole B

IL Receptor Immunology/Inflammation
cephalandole B 是一种从青黛中分离出两种吲哚生物碱,能明显地抑制了IL-17A 基因的表达,以剂量依赖的方式抑制了Jukat 细胞的IL-17A 荧光素酶报告。
T19882 Bryonolic acid

UNII-J7YR6A878I,20-epi-Bryonolic acid

Apoptosis; Antioxidant; Calcium Channel Apoptosis; Membrane transporter/Ion channel; Metabolism; oxidation-reduction
Bryonolic acid (20-epi-Bryonolic acid) 是一种从 Sandoricum indicum 提取的三萜类化合物,具有免疫调节、抗炎,抗氧化和抗癌等活性,通过抑制Ca2+内流和调节Ca2+-CaMKII-CREB信号通路中的基因表达来避免PC12细胞免受NMDA诱导的细胞凋亡反应。
T3384 Wedelolactone

蟛蜞菊内酯,IKK Inhibitor II

Apoptosis; NF-κB; Lipoxygenase; Caspase Apoptosis; Metabolism; NF-κB; Proteases/Proteasome
Wedelolactone (IKK Inhibitor II) 是来自旱莲草的一种天然产物,通过阻断 IκBα 的磷酸化和降解来抑制细胞中 NF-κB 介导的基因转录,具有抗癌,抗炎和抗氧化活性。
TN1334 7-Methoxyrosmanol

7ALPHA-甲氧基迷迭香酚,7-O-Methylrosmanol

cAMP GPCR/G Protein
7-Methoxyrosmanol (7-O-Methylrosmanol) 是一种酚类二萜,从迷迭香中分离得到,可抑制 PEPCK 和 G6Pase 启动子的 cAMP 反应。
T41031 Protamine sulfate

Thrombin Proteases/Proteasome
Protamine sulfate是一种多阳离子肽类,作为一种抗肝素剂。该化合物能中和肝素的抗凝作用并增强脂质介导的基因转移。
TN6739 Angoline

6-Methoxyldihydrochelerythrine

IL Receptor; STAT Immunology/Inflammation; JAK/STAT signaling; Stem Cells
Angoline (6-Methoxyldihydrochelerythrine) 是选择性 IL6/STAT3信号通路的抑制剂,IC50为 11.56 μM。它抑制 STAT3 磷酸化及其靶基因表达,并抑制癌细胞增殖。
T1034 Docetaxel

多西他赛,NSC 628503,RP-56976,多烯紫杉醇

Apoptosis; Microtubule Associated; Endogenous Metabolite Apoptosis; Cytoskeletal Signaling; Metabolism
Docetaxel (RP-56976) 是紫杉醇的半合成类似物,是一种微管解聚抑制剂 (IC50=0.2 μM)。Docetaxel 可以减弱 bcl-2 和 bcl-xL 基因表达的影响,具有诱导凋亡、抗肿瘤活性。
T1339 5-Azacytidine

阿托胞苷,Azacitidine,NSC 102816,Mylosar,Ladakamycin,5-氮杂胞苷,5-AzaC

Nucleoside Antimetabolite/Analog; DNA Methyltransferase; Antibacterial; Antibiotic; Autophagy Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair; Microbiology/Virology
5-Azacytidine (Ladakamycin) 是一种胞苷核苷类似物,一种 DNA 甲基化抑制剂,具有特异性。5-Azacytidine 通过降低 DNA 甲基化水平调节基因表达。5-Azacytidine 可以诱导细胞自噬,具有抗肿瘤活性。
TMS2182 trans-Zeatinriboside

Ribosylzeatin,Zeatin Riboside,Trans-Zeatin Riboside,玉米素核苷

Others Others
trans-Zeatinriboside (Ribosylzeatin) 是一种细胞分裂素前体,是木质素导管中主要的长距离信号形式,能够调节叶片大小和分生组织活性相关形状。
T8189 Dihydroberberine

Potassium Channel; HSP; HER Angiogenesis; Cytoskeletal Signaling; JAK/STAT signaling; Membrane transporter/Ion channel; Metabolism; Tyrosine Kinase/Adaptors
Dihydroberberine 可抑制人类 ether-a-go-go 相关基因 (hERG) 通道并显着降低 Hsp90 表达及其与 hERG 的相互作用,具有抗动脉粥样硬化、抗炎、降血脂和抗肿瘤活性。
Fr14115 α-Terpineol

Terpineol,α-松油醇

IL Receptor; Anti-infection; Antibacterial Immunology/Inflammation; Microbiology/Virology
α-Terpineol (Terpineol) 是从蓝桉中分离出来的,对须癣毛癣菌有抗真菌活性,对牙周病和致龋菌有抗菌活性。它还具有抗惊厥和抗炎活性。
T3829 Ginsenoside F3

人参皂苷F3

Others; IFNAR; Interleukin Immunology/Inflammation; Others
Ginsenoside F3 是一种皂苷,提取自Panax ginseng 叶片。它能够调节1 型 (IL-2, IFN-γ) 及 2 型细胞因子(IL-4 and IL-10) 的产生和表达,有免疫增强的作用。
T0603 Phthalic acid mono-2-ethylhexyl ester

DEHP,Phthalic Acid Monooctyl Ester,邻苯二甲酸单乙基己基酯

P450; Endogenous Metabolite Metabolism
Phthalic acid mono-2-ethylhexyl ester (Phthalic Acid Monooctyl Ester) 是diethylhexyl phthalate (DEHP) 的主要生物活性代谢物,能够抑制 CYP17 的 17,20 裂合酶特性。
T1429 17α-Hydroxyprogesterone

Hydroxyprogesterone,17-OHP,羟孕酮,17-Hydroxyprogesterone,17α-羟孕酮

Estrogen/progestogen Receptor; Progesterone Receptor; Endogenous Metabolite Endocrinology/Hormones; Metabolism; Others
17α-Hydroxyprogesterone (17-OHP) 是一种内源性孕激素,其他类固醇激素(包括糖皮质激素,雌激素,和雄激素)生物合成的化学中间体。
TN2331 Eleutheroside B1

刺五加苷B1

Influenza Virus Microbiology/Virology
Eleutheroside B1是具有广谱抗人流感病毒的一种香豆素。它抑制多种趋化因子基因和流感病毒核蛋白基因的 mRNA 表达。它具有抗病毒、抗流感和抗炎活性,且细胞毒性小。
T0610 Piceatannol

白皮杉醇,trans-Piceatannol,Astringenin

Apoptosis; Serine/threonin kinase; PKA; Syk; PKC; Autophagy Angiogenesis; Apoptosis; Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism; Tyrosine Kinase/Adaptors
Piceatannol (Astringenin) 是一种Syk 抑制剂,可降低由 TNF 诱导的 iNOS 表达,可研究急性肺损伤。它是存在于各种水果和蔬菜中天然存在的多酚二苯乙烯,可诱导细胞自噬和凋亡,具有抗癌和抗炎特性。
T7929 L-Aspartic Acid 4-Benzyl Ester

Others Others
L-Aspartic Acid 4-Benzyl Ester 是一种螯合剂,与金属离子形成稳定的络合物,已用于研究金属离子对酶活性的影响,以及研究金属离子在基因表达调控中的作用等。
T2S2108 Coixol

薏苡素,6-methoxybenzoxazolone,6-MBOA,6-Methoxy-2-benzoxazolinone,MBOA

Others; Antibacterial Microbiology/Virology; Others
Coixol (MBOA) 是一种从薏苡仁中提取的多酚,有抗菌和抗肿瘤作用。
T3676 Sesamol

1,3-Benzodioxol-5-ol,3,4-Methylenedioxyphenol,芝麻酚

Apoptosis; AMPK Apoptosis; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
Sesamol (1,3-Benzodioxol-5-ol) 是芝麻油的主要成分,具有抗氧化和抗肿瘤活性。它是一种自由基清除剂,在 DPPH 实验中,IC50为 5.95±0.56 μg/mL。
T6S2246 Alisol B 23-acetate

Alisol B Acetate,Alisol B monoacetate,23-O-Acetylalisol B,23-Acetylalismol B,泽泻醇B乙酸酯

Others Others
Alisol B 23-acetate (Alisol B Acetate) 是三萜类化合物,能够激活法尼醇受体,诱导受损的肝脏再生。
T6S0525 Farrerol

ERK; p38 MAPK; Akt Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling
Farrerol 是一种杜鹃花的生物活性成分,具有抗氧化、抗肿瘤、抗炎、神经保护和肝保护等多种功能。
T64744 Ovalbumins

Endogenous Metabolite Metabolism
Ovalbumins 是蛋清中的主要蛋白质。Ovalbumins 具有多种生物活性,如降压、抗菌、抗癌、抗氧化和免疫调节活性。Ovalbumins 是雌激素或孕酮处理的输卵管中合成的丰富的蛋白质。Ovalbumins 通常用作研究激素控制该组织中基因表达的标志物。
T5267 N-Acetyl-L-glutamic acid

Ac-L-Glu-OH,N-乙酰-L-谷氨酰胺,N-Acetylglutamic acid

Others; Endogenous Metabolite Metabolism; Others
N-Acetyl-L-glutamic acid (Ac-L-Glu-OH) 是一种 N-Acyl-L-氨基酸,是动物细胞培养基的组成成分,是一种酿酒酵母和人类的代谢物。
T4137 4,7-DIHYDROXYCOUMARIN

Others Others
4,7-DIHYDROXYCOUMARIN 是一种天然存在的香豆素衍生物,存在于多种植物中,包括欧芹和洋甘菊。已经发现它可以抑制几种酶的活性,包括细胞色素P450、环氧合酶和脂氧合酶;也可以与DNA 结合,调节基因表达,并抑制细胞周期进展;还可以诱导肿瘤细胞凋亡并减轻炎症。
T3976 Cytosporone B

Csn-B,Dothiorelone G

Others Others
Cytosporone B (Dothiorelone G) 是一种天然存在的核孤儿受体Nur77/NR4A1激动剂(EC50=0.278 nM)。
TL0008 Gigantol

Wnt/beta-catenin; Glucosidase Cytoskeletal Signaling; Metabolism; Stem Cells
Gigantol 是一种联苄基化合物,从几种药用兰花中获得,是一种Wnt/β-catenin 通路抑制剂,具有抗肿瘤活性。
T4S0878 Prunetin

樱黄素,Prunusetin

ERK; Dehydrogenase; NF-κB MAPK; Metabolism; NF-κB
Prunetin (Prunusetin) 是一种O-甲基化异黄酮,具有抗炎的作用。它是人醛脱氢酶的有效抑制剂。
T25664 Lepidiline A

Macaline A

Others Others
Lepidiline A (Macaline A) 是一种具有抗炎症活性的黄酮木质素。Lepidiline A 对HL-60细胞具有细胞毒活性,IC50值为 32.3 μM。它是从芸苔科植物Lepidium meyenii Walpers 的活性成分,可改善小鼠内源性性激素的平衡,提高果蝇的繁殖力。Lepidiline A 靶向HSD17B1基因的机制来增强酶的活性,提高性激素的生物转化效率,提高生殖能力。Lepidiline A 具有抗癌活性。
T38373 2-heptyl-3-hydroxy-4(1H)-Quinolone

2-heptyl-3-hydroxy-4(1H)-Quinolone,PQS,Pseudomonas Quinolone Signal

Others Others
2-heptyl-3-hydroxy-4(1H)-Quinolone (Pseudomonas Quinolone Signal) 是一种铜绿假单胞菌为应对细胞密度增加而产生的一种法定人数感应信号分子。 它增加了铜绿假单胞菌中lasB 基因的表达,增加代谢物焦蓝蛋白和凝集素PA-IL 的分泌,以及增加铜绿假单胞菌种群的生物膜生产。当使用浓度为40 μM 时,它还会降低铜绿假单胞菌生长介质中的铁含量,并在硫酸铁溶液中充当一种铁螯合剂。
T37753 Aureusimine B

Cysteine Protease; Antibacterial Microbiology/Virology; Proteases/Proteasome
Aureusimine B 是一种钙蛋白酶抑制剂,由金黄色葡萄球菌生物膜产生,可能是金黄色葡萄球菌生物膜感染的潜在生物标志物。
T4S1057 Tripdiolide

IL Receptor; TNF Apoptosis; Immunology/Inflammation
Tripdiolide has cytotoxic, and anti-rheumatic activities, it suppresses pro-inflammatory gene expression, may be effective therapy for lupus nephritis.
T13577 β-Zearalenol

Others Others
β-Zearalenol, a non-steroidal estrogenic mycotoxin synthesized by Fusarium species, potentially influences transcription and affects gene expression on the translational level.
T38561 Chitopentaose pentahydrochloride

Others Others
Chitopentaose pentahydrochloride is an anti-inflammatory chitosan oligosaccharide that functions as a substrate for the gene encoding chitinase B (FjchiB).
TMA0237 Carlinoside

Nrf2 Immunology/Inflammation
Carlinoside could be a worthy choice to intervene hyperbilirubinemia due to liver dysfunction. Carlinoside upregulates Nrf2 gene expression, increases its nuclear translocation and stimulates UGT1A1 promoter activity.
T17270 Yatein

Others Others
Yatein inhibits herpes simplex virus type 1 replication by interruption the immediate-early gene expression. Yatein is a lignan isolated from A. chilensis. It also has antiproliferative activity.
TN4115 Gardenine

Others Others
Gardenin has regulatory effect on the gene expression in rats with focal cerebral ischemia.
TN3937 ent-16alpha,17-Dihydroxyatisan-3-one

P-gp Membrane transporter/Ion channel; Neuroscience
ent-16alpha,17-Dihydroxyatisan-3-one and ent-16alpha,17-dihydroxykauran-3-one have apoptosis induction activities on L5178 human MDR1 gene-transfected mouse lymphoma cells.
T68731 Myxothiazol

Others Others
Myxothiazol is an inhibitor of mitochondrial respiratory chain complexes III. Myxothiazol induces transcription of the p53-responsive SESN2 gene that plays an important role in stress response and homeostatic regulation.
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天然产物

Ponasterone A
Cat.No: T21205
Synonym: 坡那甾酮A,AI3-44686
Target: Others
Pyrazinamide
Cat.No: T1426
Synonym: Pyrazinoic acid amide,Pyrazinecarboxamide,吡嗪酰胺
Target: Antibacterial, Antibiotic, Autophagy, Fatty Acid Synthase
Fustin
Cat.No: TN1653
Synonym:
Target: ERK, Beta Amyloid, AChR
Roseoflavin
Cat.No: T24729
Synonym:
Target: Antibacterial
Ginsenoside Rb2
Cat.No: T3919
Synonym: Ginsenoside C,人参皂苷 Rb2,人参皂苷Rb2
Target: GPR, Others, Influenza Virus, Endogenous Metabolite
3,5-Diiodo-L-thyronine
Cat.No: T4461
Synonym: 3,5-二碘-L-甲状腺素,Diiodothyronine
Target: Thyroid hormone receptor(THR), Endogenous Metabolite
Glycitein
Cat.No: T6S0325
Synonym: 黄豆黄素,Glycetein
Target: Apoptosis, Others
dl-Maackiain
Cat.No: T6S0214
Synonym: (+)-Maackiain,高丽槐素,Demethylpterocarpin
Target: Apoptosis, Parasite
Lucidin
Cat.No: TJS0405
Synonym: NSC 30546,芦西定;卢西定,卢西定,亮黄素,Henine
Target: Others
Kuromanin chloride
Cat.No: T3406
Synonym: Glucocyanidin chloride,Chrysontemin,矢车菊素-3-O-葡萄糖苷,Chrysontemin chloride,Cyanidin 3-O-glucoside chloride
Target: NF-κB
Halofuginone hydrobromide
Cat.No: T3524
Synonym: 卤夫酮溴氢酸盐,Tempostatin,RU-19110 (hydrobromide),Stenorol,常山酮溴酸盐
Target: Others, Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad
Cholesteryl oleate
Cat.No: T19237
Synonym: 胆固醇油酸酯,Oleoylcholesterol,Cholesterol Oleate,Cholesteryl cis-9-octadecenoate
Target: Endogenous Metabolite
Cephalandole B
Cat.No: TN7236
Synonym:
Target: IL Receptor
Bryonolic acid
Cat.No: T19882
Synonym: UNII-J7YR6A878I,20-epi-Bryonolic acid
Target: Apoptosis, Antioxidant, Calcium Channel
Wedelolactone
Cat.No: T3384
Synonym: 蟛蜞菊内酯,IKK Inhibitor II
Target: Apoptosis, NF-κB, Lipoxygenase, Caspase
7-Methoxyrosmanol
Cat.No: TN1334
Synonym: 7ALPHA-甲氧基迷迭香酚,7-O-Methylrosmanol
Target: cAMP
Protamine sulfate
Cat.No: T41031
Synonym:
Target: Thrombin
Angoline
Cat.No: TN6739
Synonym: 6-Methoxyldihydrochelerythrine
Target: IL Receptor, STAT
Docetaxel
Cat.No: T1034
Synonym: 多西他赛,NSC 628503,RP-56976,多烯紫杉醇
Target: Apoptosis, Microtubule Associated, Endogenous Metabolite
5-Azacytidine
Cat.No: T1339
Synonym: 阿托胞苷,Azacitidine,NSC 102816,Mylosar,Ladakamycin,5-氮杂胞苷,5-AzaC
Target: Nucleoside Antimetabolite/Analog, DNA Methyltransferase, Antibacterial, Antibiotic, Autophagy
trans-Zeatinriboside
Cat.No: TMS2182
Synonym: Ribosylzeatin,Zeatin Riboside,Trans-Zeatin Riboside,玉米素核苷
Target: Others
Dihydroberberine
Cat.No: T8189
Synonym:
Target: Potassium Channel, HSP, HER
α-Terpineol
Cat.No: Fr14115
Synonym: Terpineol,α-松油醇
Target: IL Receptor, Anti-infection, Antibacterial
Ginsenoside F3
Cat.No: T3829
Synonym: 人参皂苷F3
Target: Others, IFNAR, Interleukin
Phthalic acid mono-2-ethylhexyl ester
Cat.No: T0603
Synonym: DEHP,Phthalic Acid Monooctyl Ester,邻苯二甲酸单乙基己基酯
Target: P450, Endogenous Metabolite
17α-Hydroxyprogesterone
Cat.No: T1429
Synonym: Hydroxyprogesterone,17-OHP,羟孕酮,17-Hydroxyprogesterone,17α-羟孕酮
Target: Estrogen/progestogen Receptor, Progesterone Receptor, Endogenous Metabolite
Eleutheroside B1
Cat.No: TN2331
Synonym: 刺五加苷B1
Target: Influenza Virus
Piceatannol
Cat.No: T0610
Synonym: 白皮杉醇,trans-Piceatannol,Astringenin
Target: Apoptosis, Serine/threonin kinase, PKA, Syk, PKC, Autophagy
L-Aspartic Acid 4-Benzyl Ester
Cat.No: T7929
Synonym:
Target: Others
Coixol
Cat.No: T2S2108
Synonym: 薏苡素,6-methoxybenzoxazolone,6-MBOA,6-Methoxy-2-benzoxazolinone,MBOA
Target: Others, Antibacterial
Sesamol
Cat.No: T3676
Synonym: 1,3-Benzodioxol-5-ol,3,4-Methylenedioxyphenol,芝麻酚
Target: Apoptosis, AMPK
Alisol B 23-acetate
Cat.No: T6S2246
Synonym: Alisol B Acetate,Alisol B monoacetate,23-O-Acetylalisol B,23-Acetylalismol B,泽泻醇B乙酸酯
Target: Others
Farrerol
Cat.No: T6S0525
Synonym:
Target: ERK, p38 MAPK, Akt
Ovalbumins
Cat.No: T64744
Synonym:
Target: Endogenous Metabolite
N-Acetyl-L-glutamic acid
Cat.No: T5267
Synonym: Ac-L-Glu-OH,N-乙酰-L-谷氨酰胺,N-Acetylglutamic acid
Target: Others, Endogenous Metabolite
4,7-DIHYDROXYCOUMARIN
Cat.No: T4137
Synonym:
Target: Others
Cytosporone B
Cat.No: T3976
Synonym: Csn-B,Dothiorelone G
Target: Others
Gigantol
Cat.No: TL0008
Synonym:
Target: Wnt/beta-catenin, Glucosidase
Prunetin
Cat.No: T4S0878
Synonym: 樱黄素,Prunusetin
Target: ERK, Dehydrogenase, NF-κB
Lepidiline A
Cat.No: T25664
Synonym: Macaline A
Target: Others
2-heptyl-3-hydroxy-4(1H)-Quinolone
Cat.No: T38373
Synonym: 2-heptyl-3-hydroxy-4(1H)-Quinolone,PQS,Pseudomonas Quinolone Signal
Target: Others
Aureusimine B
Cat.No: T37753
Synonym:
Target: Cysteine Protease, Antibacterial
Tripdiolide
Cat.No: T4S1057
Synonym:
Target: IL Receptor, TNF
β-Zearalenol
Cat.No: T13577
Synonym:
Target: Others
Chitopentaose pentahydrochloride
Cat.No: T38561
Synonym:
Target: Others
Carlinoside
Cat.No: TMA0237
Synonym:
Target: Nrf2
Yatein
Cat.No: T17270
Synonym:
Target: Others
Gardenine
Cat.No: TN4115
Synonym:
Target: Others
ent-16alpha,17-Dihydroxyatisan-3-one
Cat.No: TN3937
Synonym:
Target: P-gp
Myxothiazol
Cat.No: T68731
Synonym:
Target: Others
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Cat. No. Product Name Species Expression System
TMPY-05092 LAG-3 Protein, Cynomolgus, Recombinant (74 Pro, His)

lymphocyte-activation gene 3

Cynomolgus HEK293 Cells
LAG-3 Protein, Cynomolgus, Recombinant (74 Pro, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.4 kDa and the accession number is XP_005570011.1.
TMPY-04730 LAG-3 Protein, Human, Recombinant (His)

LAG-3,lymphocyte-activation gene 3,CD223

Human HEK293 Cells
LAG-3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.6 kDa and the accession number is P18627-1.
TMPY-04939 LAG-3 Protein, Human, Recombinant

LAG-3,lymphocyte-activation gene 3,CD223

Human HEK293 Cells
LAG-3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.3 kDa and the accession number is P18627-1.
TMPH-00003 LASP1 Protein, Human, Recombinant (His)

LIM and SH3 domain protein 1,Metastatic lymph node gene<...

Human P. pastoris (Yeast)
LASP1 Protein, Human, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 31.2 kDa; 43 kDa, reducing conditions and the accession number is Q14847.
TMPH-00004 RAC1 Protein, Human, Recombinant (His)

Ras-like protein TC25,p21-Rac1,RAC1,Cell migration-inducing ...

Human P. pastoris (Yeast)
RAC1 Protein, Human, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 24.6 kDa; 30 kDa, reducing conditions and the accession number is P63000.
TMPY-03759 LAG-3 Protein, Rat, Recombinant (His)

lymphocyte-activation gene 3

Rat HEK293 Cells
LAG-3 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.1 kDa and the accession number is Q5BK54.
TMPY-02683 CSAG1 Protein, Human, Recombinant (hFc)

CSAGE,CT24.1,chondrosarcoma associated gene 1

Human HEK293 Cells
CSAG1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35.2 kDa and the accession number is Q6PB30-1.
TMPJ-00778 HER2/ERBB2 Protein, Human, Recombinant (His)

TKR1,Metastatic lymph node gene 19 protein,ERBB2,Pr...

Human HEK293 Cells
HER2/ERBB2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 90-120 KDa and the accession number is P04626.
TMPY-00027 GSTT2B Protein, Human, Recombinant (His)

GSTT2P,glutathione S-transferase θ 2B (gene/pseudo<...

Human HEK293 Cells
GSTT2B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29 kDa and the accession number is P0CG29.
TMPH-01535 INSIG2 Protein, Human, Recombinant (His & Myc)

Insulin-induced gene 2 protein,INSIG2

Human E. coli
Oxysterol-binding protein that mediates feedback control of cholesterol synthesis by controlling both endoplasmic reticulum to Golgi transport of SCAP and degradation of HMGCR. Acts as a negative regulator of cholesterol biosynthesis by mediating the retention of the SCAP-SREBP complex in the endoplasmic reticulum, thereby blocking the processing of sterol regulatory element-binding proteins (SREBPs) SREBF1/SREBP1 and SREBF2/SREBP2. Binds oxysterol, including 22-hydroxycholesterol, 24-hydroxycho...
TMPY-04528 LAG-3 Protein, Human, Recombinant (hFc)

lymphocyte-activation gene 3,CD223,LAG-3

Human HEK293 Cells
LAG-3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 72.9 kDa and the accession number is P18627-1.
TMPH-01029 CAPN1 Protein, Human, Recombinant (His)

CANPL1,CAPN1,Calpain-1 catalytic subunit,Micromolar-calpain,...

Human E. coli
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves CTBP1 at 'Asn-375', 'Gly-387' and 'His-409'. CAPN1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 85.9 kDa and the accession number is P07384.
TMPY-04731 LAG-3 Protein, Human, Recombinant (mFc)

lymphocyte-activation gene 3,CD223,LAG-3

Human HEK293 Cells
LAG-3 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 72.6 kDa and the accession number is P18627-1.
TMPY-06931 LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated

lymphocyte-activation gene 3,CD223,LAG-3

Human HEK293 Cells
LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 74.73 kDa and the accession number is NP_002277.4.
TMPY-05130 LAG-3 Protein, Human, Recombinant, Biotinylated

lymphocyte-activation gene 3,CD223,LAG-3

Human HEK293 Cells
LAG-3 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.3 kDa and the accession number is P18627-1.
TMPH-01025 CALCA Protein, Human, Recombinant (GST)

Calcitonin gene-related peptide 1,CGRP-I,CALCA,CALC...

Human E. coli
CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP. CALCA Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 30.6 kDa and the accession number is P06881.
TMPY-05746 LAG-3 Protein, Mouse, Recombinant

lymphocyte-activation gene 3,LAG-3,Ly66,CD223

Mouse HEK293 Cells
LAG-3 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.25 kDa and the accession number is Q61790.
TMPY-04612 LAG-3 Protein, Mouse, Recombinant (His)

LAG-3,Ly66,lymphocyte-activation gene 3,CD223

Mouse HEK293 Cells
LAG-3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.7 kDa and the accession number is Q61790.
TMPY-04611 LAG-3 Protein, Mouse, Recombinant (hFc)

lymphocyte-activation gene 3,Ly66,LAG-3,CD223

Mouse HEK293 Cells
LAG-3 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 72.1 kDa and the accession number is Q61790.
TMPH-02814 Nmes1 Protein, Mouse, Recombinant (His & SUMO)

Normal mucosa of esophagus-specific gene 1 protein,...

Mouse E. coli
Nmes1 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-00531 SSB Protein, Enterobacteria phage T7, Recombinant (His & SUMO)

Single-stranded DNA-binding protein,Gene product 2....

Enterobacteria phage T7 E. coli
Single-stranded DNA-binding protein that participates in viral DNA replication, formation of concatemers, recombination and repair of double-stranded breaks. Coats the lagging-strand ssDNA as the replication fork advances and stimulates the activities of viral DNA polymerase and primase/helicase. Coordinates simultaneous synthesis of leading- and lagging-strands. Together with DNA primase/helicase, promotes pairing of two homologous DNA molecules containing complementary single-stranded regions ...
TMPH-02887 SCRG1 Protein, Mouse, Recombinant (His)

Scrapie-responsive protein 1,Scrapie-responsive gene

Mouse E. coli
N/A. SCRG1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 15.0 kDa and the accession number is O88745?.
TMPH-00532 SSB Protein, Enterobacteria phage T7, Recombinant

Gene product 2.5,Single-stranded DNA-binding protei...

Enterobacteria phage T7 P. pastoris (Yeast)
Single-stranded DNA-binding protein that participates in viral DNA replication, formation of concatemers, recombination and repair of double-stranded breaks. Coats the lagging-strand ssDNA as the replication fork advances and stimulates the activities of viral DNA polymerase and primase/helicase. Coordinates simultaneous synthesis of leading- and lagging-strands. Together with DNA primase/helicase, promotes pairing of two homologous DNA molecules containing complementary single-stranded regions ...
TMPH-00521 G3P Protein, Enterobacteria phage M13, Recombinant (His)

Minor coat protein,Gene 3 protein,III,Attachment pr...

Enterobacteria phage M13 P. pastoris (Yeast)
Plays essential roles both in the penetration of the viral genome into the bacterial host via pilus retraction and in the extrusion process. During the initial step of infection, G3P mediates adsorption of the phage to its primary receptor, the tip of host F-pilus. Subsequent interaction with the host entry receptor tolA induces penetration of the viral DNA into the host cytoplasm. In the extrusion process, G3P mediates the release of the membrane-anchored virion from the cell via its C-terminal...
TMPH-03383 Synaptotagmin-12 Protein, Rat, Recombinant (His)

Syt12,Synaptotagmin-12,Synaptotagmin XII,Synaptotagmin-relat...

Rat E. coli
Synaptic vesicle phosphoprotein that enhances spontaneous neurotransmitter release but does not effect induced neurotransmitter release. Unlike other synaptotagmins, it does not bind Ca(2+) or phospholipids. Essential for mossy-fiber long-term potentiation in the hippocampus. Synaptotagmin-12 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 50.7 kDa and the accession number is P97610.
TMPY-01579 GBA3 Protein, Human, Recombinant (His)

glucosidase, beta, acid 3 (gene/pseudogene...

Human Baculovirus Insect Cells
Cytosolic beta-glucosidase, also known as Cytosolic beta-glucosidase-like protein 1, GBA3, CBG and CBGL1 is a cytoplasm protein which belongs to theglycosyl hydrolase 1 family and Klotho subfamily. GBA3 / CBGL1 is a glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. GBA3 / CBGL1 is present in small intestine (at protein level). GBA3 / CBGL1 is expressed in liver, small intestine, colon, spleen and kidney. GBA3 / CBGL1 is down-regulated in r...
TMPH-02266 TNFAIP6 Protein, Human, Recombinant (His & Myc)

TNFAIP6,Tumor necrosis factor-inducible gene 6 prot...

Human Baculovirus Insect Cells
Possibly involved in cell-cell and cell-matrix interactions during inflammation and tumorigenesis.
TMPH-02265 TNFAIP6 Protein, Human, Recombinant (His)

Hyaluronate-binding protein,TNF-stimulated gene 6 p...

Human E. coli
Possibly involved in cell-cell and cell-matrix interactions during inflammation and tumorigenesis. TNFAIP6 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 33.1 kDa and the accession number is P98066.
TMPH-01400 GPD2 Protein, Human, Recombinant (His & Myc)

GPD2,mitohondrial glycerophosphate dehydrogenase gene

Human E. coli
Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device. GPD2 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 81.4 kDa and the accession number is P43304.
TMPJ-00321 LAG-3 Protein, Human, Recombinant (His & Avi), Biotinylated

Lymphocyte activation gene 3 protein,CD223,LAG-3,Pr...

Human HEK293 Cells
LAG-3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 60-70 KDa and the accession number is P18627.
TMPH-01645 MGP Protein, Human, Recombinant (His)

MGP,Cell growth-inhibiting gene 36 protein,Matrix G...

Human E. coli
Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation. MGP Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 13.5 kDa and the accession number is P08493.
TMPH-02064 SCRG1 Protein, Human, Recombinant (His & SUMO)

SCRG1,Scrapie-responsive gene 1 protein,Scrapie-res...

Human E. coli
SCRG1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPJ-01421 LAG-3 Protein, Cynomolgus, Recombinant (hFc)

LAG-3,Protein FDC,Lymphocyte activation gene 3 prot...

Cynomolgus HEK293 Cells
LAG-3 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90 KDa and the accession number is XP_005570011.1.
TMPH-03758 TSG101 Protein, Human, Recombinant (His & Myc & SUMO)

Tumor susceptibility gene 101 protein,ESCRT-I compl...

Human E. coli
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an intera...
TMPH-01370 SNCG Protein, Human, Recombinant (His & SUMO)

Breast cancer-specific gene 1 protein,SNCG,Synoreti...

Human E. coli
Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases. May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway. SNCG Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 29.3 kDa a...
TMPH-00754 Capsid decoration Protein, Escherichia phage lambda, Recombinant (GST)

Gene product D,Auxiliary protein D,Major capsid pro...

Escherichia phage lambda E. coli
Stabilizes the expansion of the capsid head shell after genome packaging. The packaging of viral genome in the procapsid triggers a dramatic reconfiguration of the capsid shell, expanding from roughly 50nm to 60nm while the capsid thickness decreases. 415 capsid decoration protein molecules cooperatively bind the expanded capsid, thereby stabilizing the mature capsid shell. Capsid decoration Protein, Escherichia phage lambda, Recombinant (GST) is expressed in E. coli expression system with N-GST...
TMPY-01710 IkB alpha/NFKBIA Protein, Human, Recombinant (His)

IkB α,IKBA,nuclear factor of kappa light polypeptide gen...

Human E. coli
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (IkB alpha, NFKBIA, or IKBA), is a member of the NF-kappa-B inhibitor family that function to inhibit the NF-kB transcription factor. NFKBIA inhibits NF-kB by masking the nuclear localization signals (NLS) of NF-kB proteins and keeping them sequestered in an inactive state in the cytoplasm. Also, NFKBIA blocks the ability of NF-κB transcription factors to bind to DNA, which is required for NF-kB's proper function...
TMPH-02032 GPRC5A Protein, Human, Recombinant (GST)

G-protein coupled receptor family C group 5 member A,GPRC5A,...

Human E. coli
Orphan receptor. Could be involved in modulating differentiation and maintaining homeostasis of epithelial cells. This retinoic acid-inducible GPCR provide evidence for a possible interaction between retinoid and G-protein signaling pathways. Functions as a negative modulator of EGFR signaling. May act as a lung tumor suppressor. GPRC5A Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 37.0 kDa and the accession number i...
TMPH-02866 RBBP9 Protein, Mouse, Recombinant (His)

Retinoblastoma-binding protein 9,Putative hydrolase RBBP9,B5...

Mouse P. pastoris (Yeast)
Serine hydrolase whose substrates have not been identified yet. May negatively regulate basal or autocrine TGF-beta signaling by suppressing SMAD2-SMAD3 phosphorylation. May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta through interaction with RB1 and the subsequent displacement of E2F1. RBBP9 Protein, Mouse, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 22.4 kDa and t...
TMPH-02311 WDR5 Protein, Human, Recombinant (His & SUMO)

WDR5,BMP2-induced 3-kb gene protein,WD repeat-conta...

Human E. coli
WDR5 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 52.5 kDa and the accession number is P61964.
TMPH-00882 ACTA2 Protein, Human, Recombinant (His)

Alpha-actin-2,Actin, aortic smooth muscle,Cell growth-inhibi...

Human E. coli
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. ACTA2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 47.8 kDa and the accession number is P62736.
TMPH-01126 COMMD5 Protein, Human, Recombinant (His & Myc)

Hypertension-related calcium-regulated gene protein...

Human Baculovirus Insect Cells
COMMD5 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus.
TMPJ-01177 NOV/CCN3 Protein, Mouse, Recombinant (His)

CCN family member 3,Nephroblastoma-overexpressed gene

Mouse HEK293 Cells
NOV, also called CCN3, is a secreted protein of CCN family members. CCN family members are highly conserved cysteine rich proteins sharing a common modular structure having 4 conserved domains, insulin-like growth factor-binding protein (IGFBP) domain, von Willebrand type C (VWC) domain, thrombospondin-1 (TSP-1) domain, and C-terminal (CT) domain (absent in CCN5). By specific interactions with these domains, CCN proteins modulate multiple signalling pathways including BMPs, Wnt, TGFs, Notch and ...
TMPH-01127 COMMD5 Protein, Human, Recombinant (His)

Hypertension-related calcium-regulated gene protein...

Human E. coli
COMMD5 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPJ-00706 SNCG Protein, Human, Recombinant

PRSN,Gamma-Synuclein,SNCG,BCSG1,Breast Cancer-Specific G...

Human E. coli
Gamma-Synuclein (SNCG) is a member of the Synuclein protein family. Gamma-Synuclein is mostly expressed in the peripheral nervous system and retina. Gamma-Synuclein plays a role in neurofilament network integrity and may be involved in modulating axonal architecture during development and in the adult. In addition, it may also function in modulating the keratin network in skin. SNCG expression in breast tumors has been as a marker for tumor progression. SNCG is also believed to be involved in th...
TMPH-02733 IFI27L2A Protein, Mouse, Recombinant (His)

Interferon-stimulated gene 12 protein,Ifi27l2a,Inte...

Mouse E. coli
May be involved in the interferon-induced negative regulation of the transcriptional activity of NR4A1, NR4A2 and NR4A3 through the enhancement of XPO1-mediated nuclear export of these nuclear receptors. Through the regulation of NR4A1 transcriptional activity, may play a role in the vascular response to injury. IFI27L2A Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 7.3 kDa and the accession number is Q8R412.
TMPJ-00727 PGK1 Protein, Human, Recombinant (His)

Phosphoglycerate kinase 1,Primer recognition protein 2,PGK1,...

Human HEK293 Cells
Phosphoglycerate kinase 1(PGK1) is an enzyme. It is mainly expressed in spermatogonia and Localized on the principle piece in the sperm. Its expression significantly decreased in the testis of elderly men. PGK1 involved in a critical energy-producing process known as glycolysis. It helps carry out a chemical reaction that converts a molecule called 1,3-diphosphoglycerate, which is produced during the breakdown of glucose, to another molecule called 3-phosphoglycerate during glycolysis. PGK1 may ...
TMPH-00949 APOLD1 Protein, Human, Recombinant (His)

Vascular early response gene protein,APOLD1,VERGE,A...

Human E. coli
May be involved in angiogenesis. May play a role in activity-dependent changes of brain vasculature. May affect blood-brain permeability. APOLD1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 33.4 kDa and the accession number is Q96LR9.
TMPH-03269 COMMD5 Protein, Rat, Recombinant (His & Myc)

COMM domain-containing protein 5,COMMD5,Hypertension-related...

Rat E. coli
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis. Down-regulates activation of NF-kappa-B.
TMPH-00308 ISG15 Protein, Bovine, Recombinant (His)

Interferon-stimulated gene product 17,ISG15,Ubiquit...

Bovine E. coli
ISG15 Protein, Bovine, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 21.4 kDa and the accession number is O02741.
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重组蛋白

LAG-3 Protein, Cynomolgus, Recombinant (74 Pro, His)
Cat.No: TMPY-05092
Species: Cynomolgus
Expression System: HEK293 Cells
LAG-3 Protein, Human, Recombinant (His)
Cat.No: TMPY-04730
Species: Human
Expression System: HEK293 Cells
LAG-3 Protein, Human, Recombinant
Cat.No: TMPY-04939
Species: Human
Expression System: HEK293 Cells
LASP1 Protein, Human, Recombinant (His)
Cat.No: TMPH-00003
Species: Human
Expression System: P. pastoris (Yeast)
RAC1 Protein, Human, Recombinant (His)
Cat.No: TMPH-00004
Species: Human
Expression System: P. pastoris (Yeast)
LAG-3 Protein, Rat, Recombinant (His)
Cat.No: TMPY-03759
Species: Rat
Expression System: HEK293 Cells
CSAG1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02683
Species: Human
Expression System: HEK293 Cells
HER2/ERBB2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00778
Species: Human
Expression System: HEK293 Cells
GSTT2B Protein, Human, Recombinant (His)
Cat.No: TMPY-00027
Species: Human
Expression System: HEK293 Cells
INSIG2 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01535
Species: Human
Expression System: E. coli
LAG-3 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04528
Species: Human
Expression System: HEK293 Cells
CAPN1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01029
Species: Human
Expression System: E. coli
LAG-3 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-04731
Species: Human
Expression System: HEK293 Cells
LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-06931
Species: Human
Expression System: HEK293 Cells
LAG-3 Protein, Human, Recombinant, Biotinylated
Cat.No: TMPY-05130
Species: Human
Expression System: HEK293 Cells
CALCA Protein, Human, Recombinant (GST)
Cat.No: TMPH-01025
Species: Human
Expression System: E. coli
LAG-3 Protein, Mouse, Recombinant
Cat.No: TMPY-05746
Species: Mouse
Expression System: HEK293 Cells
LAG-3 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04612
Species: Mouse
Expression System: HEK293 Cells
LAG-3 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-04611
Species: Mouse
Expression System: HEK293 Cells
Nmes1 Protein, Mouse, Recombinant (His & SUMO)
Cat.No: TMPH-02814
Species: Mouse
Expression System: E. coli
SSB Protein, Enterobacteria phage T7, Recombinant (His & SUMO)
Cat.No: TMPH-00531
Species: Enterobacteria phage T7
Expression System: E. coli
SCRG1 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02887
Species: Mouse
Expression System: E. coli
SSB Protein, Enterobacteria phage T7, Recombinant
Cat.No: TMPH-00532
Species: Enterobacteria phage T7
Expression System: P. pastoris (Yeast)
G3P Protein, Enterobacteria phage M13, Recombinant (His)
Cat.No: TMPH-00521
Species: Enterobacteria phage M13
Expression System: P. pastoris (Yeast)
Synaptotagmin-12 Protein, Rat, Recombinant (His)
Cat.No: TMPH-03383
Species: Rat
Expression System: E. coli
GBA3 Protein, Human, Recombinant (His)
Cat.No: TMPY-01579
Species: Human
Expression System: Baculovirus Insect Cells
TNFAIP6 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-02266
Species: Human
Expression System: Baculovirus Insect Cells
TNFAIP6 Protein, Human, Recombinant (His)
Cat.No: TMPH-02265
Species: Human
Expression System: E. coli
GPD2 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01400
Species: Human
Expression System: E. coli
LAG-3 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPJ-00321
Species: Human
Expression System: HEK293 Cells
MGP Protein, Human, Recombinant (His)
Cat.No: TMPH-01645
Species: Human
Expression System: E. coli
SCRG1 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-02064
Species: Human
Expression System: E. coli
LAG-3 Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPJ-01421
Species: Cynomolgus
Expression System: HEK293 Cells
TSG101 Protein, Human, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-03758
Species: Human
Expression System: E. coli
SNCG Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01370
Species: Human
Expression System: E. coli
Capsid decoration Protein, Escherichia phage lambda, Recombinant (GST)
Cat.No: TMPH-00754
Species: Escherichia phage lambda
Expression System: E. coli
IkB alpha/NFKBIA Protein, Human, Recombinant (His)
Cat.No: TMPY-01710
Species: Human
Expression System: E. coli
GPRC5A Protein, Human, Recombinant (GST)
Cat.No: TMPH-02032
Species: Human
Expression System: E. coli
RBBP9 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02866
Species: Mouse
Expression System: P. pastoris (Yeast)
WDR5 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-02311
Species: Human
Expression System: E. coli
ACTA2 Protein, Human, Recombinant (His)
Cat.No: TMPH-00882
Species: Human
Expression System: E. coli
COMMD5 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01126
Species: Human
Expression System: Baculovirus Insect Cells
NOV/CCN3 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01177
Species: Mouse
Expression System: HEK293 Cells
COMMD5 Protein, Human, Recombinant (His)
Cat.No: TMPH-01127
Species: Human
Expression System: E. coli
SNCG Protein, Human, Recombinant
Cat.No: TMPJ-00706
Species: Human
Expression System: E. coli
IFI27L2A Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02733
Species: Mouse
Expression System: E. coli
PGK1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00727
Species: Human
Expression System: HEK293 Cells
APOLD1 Protein, Human, Recombinant (His)
Cat.No: TMPH-00949
Species: Human
Expression System: E. coli
COMMD5 Protein, Rat, Recombinant (His & Myc)
Cat.No: TMPH-03269
Species: Rat
Expression System: E. coli
ISG15 Protein, Bovine, Recombinant (His)
Cat.No: TMPH-00308
Species: Bovine
Expression System: E. coli
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Cat. No. Product Name Target Signaling Pathways
T11045 Dimethyl fumarate-d6

Dimethyl fumarate D6,DMF D6

Others Others
Dimethyl fumarate D6 is a deuterium labeled Dimethyl fumarate. can induces upregulation of antioxidant gene expression.
TMIJ-0404 Dibenz[a,h]anthracene-d14

Dibenz[a,h]anthracene-d14 是 Dibenz[a,h]anthracene 的氘代化合物。Dibenz[a,h]anthracene 的 CAS 号为 53-70-3。Dibenz[a,h]anthracene诱导细菌DNA损伤和基因突变,并在几种哺乳动物细胞培养物中诱导基因突变和转化。
TMIH-0568 Tezacaftor-d4

VX-661-d4

Tezacaftor-d4 是 Tezacaftor 的氘代化合物。Tezacaftor 的 CAS 号为 1152311-62-0。VX-661 是一种小分子,可用作囊性纤维化跨膜电导调节器基因功能的校正剂。
TMID-0112 21-Deoxycortisol-d8

21-Deoxycortisol-d8 是 21-Deoxycortisol 的氘代化合物。21-Deoxycortisol 的 CAS 号为 641-77-0。
TMIJ-0204 Betamethasone-d10 Dipropionate

Betamethasone-d10 Dipropionate 是 Betamethasone Dipropionate 的氘代化合物。Betamethasone Dipropionate 的 CAS 号为 5593-20-4。Betamethasone dipropionate 是糖皮质激素类固醇,具有免疫抑制、抗炎作用。
TMIJ-0208 Beclomethasone Dipropionate-d6

Beclomethasone Dipropionate-d6 是 Beclomethasone Dipropionate 的氘代化合物。Beclomethasone Dipropionate 的 CAS 号为 5534-09-8。Betamethasone dipropionate是具有口服活性的糖皮质激素,具有抗炎和免疫抑制作用。它是Betamethasone 的前体药物,Betamethasone 是 LPS 诱导的炎症及 MMP 释放的抑制剂。
TMIJ-0163 Valproic Acid-d4

Valproic Acid-d4 是 Valproic Acid 的氘代化合物。Valproic Acid 的 CAS 号为 99-66-1。Valproic acid是一种 HDAC 抑制剂,可抑制HDAC1的活性,同时可诱导HDAC2的降解。它激活Notch1信号并抑制小细胞肺癌细胞的增殖。它可研究癫痫、双相情感障碍和偏头痛等。
TMIJ-0431 2-(Propyl-3,3,3-d3)pentanoic-5,5,5-d3 Acid

2-(Propyl-3,3,3-d3)pentanoic-5,5,5-d3 Acid 是 2-pentanoic Acid 的氘代化合物。2-pentanoic Acid 的 CAS 号为 99-66-1。Valproic acid是一种 HDAC 抑制剂,可抑制HDAC1的活性,同时可诱导HDAC2的降解。它激活Notch1信号并抑制小细胞肺癌细胞的增殖。它可研究癫痫、双相情感障碍和偏头痛等。
TMID-0120 Valproic Acid-d15

Valproic Acid-d15 是 Valproic Acid 的氘代化合物。Valproic Acid 的 CAS 号为 99-66-1。Valproic acid是一种 HDAC 抑制剂,可抑制HDAC1的活性,同时可诱导HDAC2的降解。它激活Notch1信号并抑制小细胞肺癌细胞的增殖。它可研究癫痫、双相情感障碍和偏头痛等。
T35515 3-Acetyldeoxy Nivalenol-13C17

3-Acetyldeoxy Nivalenol-13C17

3-Acetyldeoxy nivalenol-13C17is intended for use as an internal standard for the quantification of 3-acetyldeoxy nivalenol by GC- or LC-MS. 3-Acetyldeoxy nivalenol is a mycotoxin that has been found inF. graminearum.1In vivo, 3-acetyldeoxy nivalenol (40 mg/kg) induces duodenal and splenic cell necrosis, as well as lethality (LD50= 70 mg/kg) in mice.2 1.Jiao, F., Kawakami, A., and Nakajima, T.Effects of different carbon sources on trichothecene production and Tri gene expression by Fusarium grami...

同位素标记化合物

Dimethyl fumarate-d6
Cat.No: T11045
Synonym: Dimethyl fumarate D6,DMF D6
Target: Others
Dibenz[a,h]anthracene-d14
Cat.No: TMIJ-0404
Synonym:
Target:
Tezacaftor-d4
Cat.No: TMIH-0568
Synonym: VX-661-d4
Target:
21-Deoxycortisol-d8
Cat.No: TMID-0112
Synonym:
Target:
Betamethasone-d10 Dipropionate
Cat.No: TMIJ-0204
Synonym:
Target:
Beclomethasone Dipropionate-d6
Cat.No: TMIJ-0208
Synonym:
Target:
Valproic Acid-d4
Cat.No: TMIJ-0163
Synonym:
Target:
2-(Propyl-3,3,3-d3)pentanoic-5,5,5-d3 Acid
Cat.No: TMIJ-0431
Synonym:
Target:
Valproic Acid-d15
Cat.No: TMID-0120
Synonym:
Target:
3-Acetyldeoxy Nivalenol-13C17
Cat.No: T35515
Synonym: 3-Acetyldeoxy Nivalenol-13C17
Target:
TargetMol Loading
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