Nusinersen

Name: Nusinersen
Brand: TargetMol
SKU: T38656
Rating: 4.5 (1 reviews)

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产品编号 T38656Cas号 1258984-36-9

Nusinersen is an antisense oligonucleotide drug that modifies pre–messenger RNA splicing of the SMN2 gene and thus promotes increased production of full-length SMN protein.

Nusinersen

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产品编号 T38656Cas号 1258984-36-9

Nusinersen is an antisense oligonucleotide drug that modifies pre–messenger RNA splicing of the SMN2 gene and thus promotes increased production of full-length SMN protein.

规格	价格	库存	数量
5 mg	询价	期货
10 mg	询价	期货

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产品描述	Nusinersen, an antisense oligonucleotide drug, modifies the pre-messenger RNA (pre-mRNA) splicing of the SMN2 gene, thereby enhancing the production of the full-length Survival Motor Neuron (SMN) protein.
体外活性	Nusinersen is an SMN-ASO that increases SMN levels by blocking an intronic splice silencer in SMN2, thereby facilitating the exon 7 inclusion and generation of FL-SMN2 transcripts[2].