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Targets Recommended: ATPase ATP Citrate Lyase P2X Receptor

895

抑制剂 & 化合物

85

天然产物

7

化合物库

149

重组蛋白

15

同位素标记化合物

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Cat. No. Product Name
L2521 糖酵解化合物库

555 compounds
555 种糖酵解相关的活性化合物,可用于高通量和高内涵筛选
L1600 激酶抑制剂库

2720 compounds
2720 种激酶抑制剂/调节剂的独特集合,用于特定靶向激酶,可用于高通量筛选和高内涵筛选;
L1610 FDA 上市激酶抑制剂库

263 compounds
263种靶向激酶的上市药物集合,用于特定靶向激酶,可用于高通量筛选和高内涵筛选;
L1120 AMPK靶向分子库

80 compounds
80 个靶向AMPK 的分子集合,可用于高通量和高内涵筛选;
L8300 染色质修饰分子库

250 compounds
250 种染色质化学修饰相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L5300 线粒体靶向库

812 compounds
812 种具有潜在或确定线粒体靶向活性的化合物,以促进针对线粒体的药物研究;
L2550 谷氨酰胺代谢化合物库

565 compounds
565 种谷氨酰胺代谢相关的分子,可以用于高通量和高内涵筛选;

化合物库

糖酵解化合物库
Cat.No: L2521
Compounds: 555
激酶抑制剂库
Cat.No: L1600
Compounds: 2720
FDA 上市激酶抑制剂库
Cat.No: L1610
Compounds: 263
AMPK靶向分子库
Cat.No: L1120
Compounds: 80
染色质修饰分子库
Cat.No: L8300
Compounds: 250
线粒体靶向库
Cat.No: L5300
Compounds: 812
谷氨酰胺代谢化合物库
Cat.No: L2550
Compounds: 565
Cat. No. Product Name Target Signaling Pathways
T13541 α,β-Methylene ATP trisodium

P2X Receptor Membrane transporter/Ion channel; Neuroscience
α,β-Methylene ATP trisodium 是 ATP 的膦酸酯类似物,是选择性 P2X 激动剂,诱导UBSM 收缩增强。α,β-Methylene ATP trisodium 抑制 P2X1 和 P2X3 但对 P2X2, 4 和 7 没有活性。
T10404 ATP synthase inhibitor 1

ATPase Membrane transporter/Ion channel
ATP synthase inhibitor 1 是 F1/FO-ATP 合酶复合物 c 亚基的有效抑制剂,抑制线粒体通透性转换孔的开放。
T60032 BRM/BRG1 ATP Inhibitor-2

Epigenetic Reader Domain Chromatin/Epigenetic
BRM/BRG1 ATP Inhibitor-2 是 BRG1/BRM ATPase 的抑制剂,可用于治疗 BAF 相关疾病的研究。
T22592 ATPγS tetralithium salt

ATP-gamma-S tetralithium salt

PERK Apoptosis
ATPγS tetralithium salt 是真核生物翻译起始因子 eIF4A 的核苷酸水解和RNA解链活性的底物,与 p97 突变体和朊病毒相关。
T10616 BRM/BRG1 ATP Inhibitor-1

Epigenetic Reader Domain Chromatin/Epigenetic
BRM/BRG1 ATP Inhibitor-1 是变构双 Brahma 同源物 (BRM)/SWI/SNF 相关的基质相关肌动蛋白依赖性调节剂,染色质亚家族 A 成员 2 和 BRG1/SMARCA4 ATP 酶活性抑制剂,IC50值低于 0.005 μM。
T39891 8-Bromo-ATP

8-Bromoadenosine 5'-triphosphate,8-Bromo-ATP,8-Br-ATP

Others Others
8-Bromo-ATP (8-Bromoadenosine 5'-triphosphate) is a purinergic P2X receptor agonist and an ATP analogue. It exhibits cytotoxicity towards multiple myeloma cells, with an IC50 of 23.1 μM.
T40616 8-Azido-ATP

8-Azidoadenosine 5'-triphosphate,8-N3-ATP,8-Azido-ATP

Others Others
8-Azido-ATP is a nucleotide analog that demonstrates photo-reactivity properties. It offers utility in the precise labeling and identification of proteins, particularly those involved in DNA-dependent RNA polymerase activity.
T75325 ATP dimagnesium

Others Others
ATP dimagnesium 是体内能量储存和代谢的重要物质,参与机体的能量循环和代谢能量。ATP dimagnesium 可在细胞中充当辅酶,可被当做一种信号分子。
T40455 8-NH2-ATP

8-Aminoadenosine-5'-O-triphosphate,8-NH2-ATP

Others Others
8-NH2-ATP is an inactive derivative of adenosine triphosphate (ATP), synthesized from 8-NH2-Ado. It has been documented that 8-NH2-Ado exhibits potent properties, as evidenced by its ability to induce apoptosis-associated cleavage of poly(ADP-ribose) polymerase.
T40696 2'-NH2-ATP

2'-NH2-ATP,2'-Amino-2'-deoxyadenosine-5'-triphosphate

Others Others
2'-NH2-ATP (2'-Amino-2'-deoxyadenosine-5'-triphosphate) is an adenosine derivative compound that acts as a weak competitive inhibitor of ATP with a K i value of 2.3 mM. It finds utility in nucleic acid labeling.
T60877 Mtb ATP synthase-IN-1

ATPase Membrane transporter/Ion channel
Mtb ATP synthase-IN-1 是一种可口服的结核分枝杆菌 (Mtb) ATP 合成抑制剂,可用于研究结核分枝杆菌感染。
T22496 2-Methylthio-ATP tetrasodium

2-Methylthioadenosine triphosphate tetrasodium salt,2-methylthio-atp-tetrasodium

Others Others
P2 purinoceptor agonist
T17454 ATP-polyamine-biotin

Others Others
ATP-polyamine-biotin is a cell-permeable, efficient kinase cosubstrate with conversions and kinetics similar to those of other known ATP analogues. APB shows a cytotoxicity EC50 value of 19 ± 1 mM. ATP-polyamine-biotin is shown to promote biotin labeling
T38444 α,β-Methylene-ATP dilithium

Others Others
α,β-Methylene ATP dilithium, a phosphonic analog of ATP, serves as a ligand for P2X3 and P2X7 receptors. It is a potent agonist specifically targeting P2X1 and P2X3 receptors while exerting negligible activity on P2X2, P2X4, P2X5, P2X6, and P2X7 receptors.
T18917 ATP-Red 1

Others Others
ATP-Red 1 is a multisite-binding switchable fluorescent probe. It can rapidly and selectively respond to intracellular concentrations of ATP in living cells.
T69111 2',3'-Dialdehyde ATP

Others Others
2',3'-Dialdehyde ATP is a derivative of, and the oxidized form of, ATP. It has been found to be a specific, irreversible inhibitor of component A3 of the methylreductase system which plays a role in processing amino acids.
T22738 DMNPE-caged ATP diammonium salt

Others Others
DMNPE-caged ATP
T40522 3'-Deoxy-3'-amino-ATP

Others Others
3'-Deoxy-3'-amino-ATP, an ATP analogue, is a highly effective and competitive inhibitor of ATP, exhibiting a K i value of 2.3 μM. Its application includes the synthesis of 3′-Amino-3′-deoxy transfer RNA by integrating it into the 3' terminus of tRNA-C-C.
TP2297 TNP-ATP triethylammonium salt

Others Others
P2X receptor antagonist
T75326 ATP ditromethamine

Others Others
ATP ditromethamine(Adenosine 5'-triphosphate ditromethamine)作为体内能量储存和代谢的核心物质,不仅为代谢过程提供必需能量,而且在细胞中担任辅酶角色。此外,它在免疫和炎症反应中,扮演着关键的内源性信号分子角色。
T74033 6-Me-ATP

Others Others
6-Me-ATP(N6-Methyl-ATP)为ATP的N6修饰衍生物。该化合物与GSK3β结合亲和力显著,能有效作为GSK3β催化底物肽磷酸化的磷酸基团供体。
T83802 TNP-ATP sodium

TNP-ATPATP的衍生物,同时是嘌呤P2Y1、P2X3和P2X2/3受体的拮抗剂(IC50s分别为6、0.9和7 nM,在表达人类受体的HEK293细胞中)。该化合物相对于嘌呤P2X2、P2X4和P2X7受体显示出选择性(IC50s分别为2、15.2和>30 µM,在表达人类受体的HEK293细胞中)。TNP-ATP能降低表达P2X3和P2X2/3受体的1321N1细胞中乙酸诱导的钙流量(IC50s分别为100和62 nM)。它还可以减轻小鼠模型中由乙酸诱发的痛性绞曲(ED50 = 6.35 µmol/kg)。在403 nm激发下,其发射最大峰值为547 nm,当结合于胰岛素降解酶(IDE)时,其相对荧光强度增加四倍,并且发射峰移至538 nm。
T82944 ATP Synthesis-IN-2

Others Others
ATP Synthesis-IN-2 (Compound 5) 是一种有效的ATP合成活性抑制剂,对Pseudomonas aeruginosa (PA) 表现出抗菌活性,其IC50值为0.7 μg/mL。
T79586 3′-Acetate-ATP

Others Others
3’-Acetate-ATPATP的乙酰化衍生物,表现为ATP类似物,其在中性pH值的水溶液中于259 nm波长处展现出最大的紫外线吸收。该化合物能够抑制核酸聚合酶活性,从而阻断核酸的延伸。
T84928 2-Chloroadenosine 5-triphosphate sodium

2-chloro ATP

Others Others
2-Chloroadenosine 5-triphosphate (2-chloro ATP), an analog of ATP and adenine nucleotide, functions as an antagonist of the purinergic P2Y1 receptor, inhibiting ADP-induced intracellular calcium mobilization in Jurkat cells with a Ki value of 2.3 µM. Additionally, 2-chloro ATP acts as an agonist of purinergic P2X receptors, demonstrated by inducing inward currents in HEK293 cells expressing either human bladder smooth muscle or rat PC12 receptor forms, with EC50 values of 0.5 and 2.5 µM, respect...
T78639 Oxidized ATP trisodium salt

oATP trisodium salt

P2X Receptor Membrane transporter/Ion channel; Neuroscience
Oxidized ATP (oATP) trisodium salt 是一种P2 受体广泛抑制剂,其不可逆地阻断P2X7R活化并抑制CRP引发的NLRP3炎性体激活,常用于动脉粥样硬化研究。
T82945 ATP Synthesis-IN-1

Others Others
ATP Synthesis-IN-1(Compound 4)为喹啉衍生物,有效抑制PA ATP合成,IC50为11.1μg/mL。本化合物亦展示抗菌特性,适用于研究耐药PA感染。
T84731 8-NH2-ATP tetrasodium

8-Aminoadenosine-5'-O-triphosphate tetrasodium

Others Others
8-NH2-ATP tetrasodium,一种ATP的非活性形式,源自8-NH2-Ado。8-NH2-Ado tetrasodium能够诱导与凋亡相关的poly (ADP-ribose)聚合酶裂解。
T72590 α,β-Methylene-ATP

Others Others
α,β-Methylene ATP,一种ATP的膦酸酯类似物,充当P2X3和P2X7受体的配体。该化合物对P2X1和P2X3表现出高选择性激动剂活性,而在P2X2, 4, 7受体上无活性。
T61649 ATP synthase inhibitor 2

Others Others
ATP synthase inhibitor2 是一个铜绿假单胞菌 (PA)ATP synthase 抑制剂 (IC50=10 μg/mL),在 128 μg/mL 时可完全抑制铜绿假单胞菌 (PA) 的 ATP 合成活性。
T83786 8-Chloroadenosine-5'-triphosphate sodium

8-chloro ATP

Others Others
8-Chloroadenosine-5’-triphosphate(8-chloro ATP)是抗癌剂8-chloro cAMP的活性代谢物,也是核苷酸腺苷5’-三磷酸(ATP)的衍生物。它通过8-chloro cAMP、8-chloroadenosine以及一磷酸和二磷酸中间体形成。应用8-chloro cAMP或8-chloroadenosine后,8-chloro ATP可累积长达12小时,与细胞生长抑制、内源性ATP水平下降以及患者源多发性骨髓瘤细胞中RNA合成减少(但DNA合成不受影响)相关。在1.5至8 mM浓度范围内,它抑制topoisomerase II-α依赖的超螺旋pUC19 DNA放松,同时在1 mM时减少了K562人髓性白血病细胞中topoisomerase II-α催化的ATP水解50%。
T74034 6-Me-ATP trisodium

Others Others
6-Me-ATP trisodium (N6-Methyl-ATP) 是N6-修饰的ATP衍生物,展现对GSK3良好的结合亲和力,可作为GSK3β磷酸化底物肽的磷酸基团供体。
T83808 Sp-Adenosine-5'-O-(1-thiotriphosphate) sodium

Sp-ATP-α-S

Others Others
Sp-Adenosine-5'-O-(1-thiotriphosphate) (Sp-ATP-α-S) 是一种含硫核苷酸衍生物 ATP-α-S 的异构体,也是嘌呤P2Y1受体的激动剂。在表达P2Y1受体的HEK293细胞中增加钙离子的流动(对人类受体的EC50 = 9.4 nM)。Sp-ATP-α-S 抑制了ADP诱导的孤立人类血小板聚集(Ki = 4 μM)。它还能引起经卡巴胆碱预收缩的豚鼠十二指肠松弛(EC50 = 426 nM)。
T83807 Rp-Adenosine-5'-O-(1-thiotriphosphate) sodium

Rp-ATP-α-S

Others Others
Rp-Adenosine-5'-O-(1-thiotriphosphate)(Rp-ATP-α-S)是一种含硫核苷酸衍生物ATP-α-S的异构体,同时也是嘌呤P2Y1受体的激动剂。在表达人类P2Y1受体的HEK293细胞中,Rp-ATP-α-S能增加钙的动员(EC50 = 75 nM)。该化合物与洗涤的人类孤立血小板结合(Ki = 156 nM),抑制由ADP引发的人类富血小板血浆(PRP)的聚集(pA2 = 4.74),并且能够抑制前列腺素E1(PGE1)在人类孤立PRP中引发的cAMP产生(pA2 = 5.26)。同时,Rp-ATP-α-S还能引起用氨基甲酰胆碱预先缩紧的豚鼠结肠条带的松弛(EC50 = 56 nM)。此外,Rp-ATP-α-S已经被用于合成被细菌核糖开关识别的环状二核苷酸。
T83811 2'(3')-O-Anthraniloyladenosine-5'-O-triphosphate sodium

2'(3')-ANT-ATP

2'(3')-O-Anthraniloyladenosine-5'-O-triphosphate(2'-ANT-ATP)与3'-ANT-ATP是荧光ATP衍生物,可自发地进行异构化。在水中,2'(3')-ANT-ATP的激发波长为330 nm时,发射最大波长为428 nm。它对哺乳动物腺苷酸环化酶(AC1)、AC2及AC5显示出抑制作用,抑制常数(Kis)分别为130、640和120 nM。此外,它还能抑制百日咳杆菌腺苷酸环化酶毒素CyaA(在锰和镁存在下,Kis分别为1.3和20 µM)、炭疽杆菌腺苷酸环化酶毒素水肿因子(在锰和镁存在下,Kis分别为0.44和5.15 µM)以及大肠杆菌重组酶A(RecA;Ki = 6.3 µM)。
T72257 BRM/BRG1 ATP Inhibitor-3

Others Others
BRM/BRG1 ATP Inhibitor-3为一种针对BRG1/BRM的抑制剂,具有分别针对BRM和BRG1的IC50值为10.4 nM及19.3 nM,适用于癌症与BAF复合物相关疾病的研究。
T79004 ATP synthase inhibitor 2 TFA

Others Others
ATP synthase inhibitor2 (Compound 22) TFA 为针对铜绿假单胞菌 (PA) ATP synthase 的抑制剂,具IC50值为10 μg/mL,在浓度达到128 μg/mL 时能够全面阻断铜绿假单胞菌 (PA) ATP的合成活性。
T72258 BRM/BRG1 ATP Inhibitor-4

Others Others
BRM/BRG1 ATP Inhibitor-4 是一种BRG1/BRM 抑制剂。BRM/BRG1 ATP Inhibitor-4 可用于癌症和 BAF 复合物相关疾病的研究。
T15373 Gboxin

ATPase; Mitochondrial Metabolism Membrane transporter/Ion channel; Metabolism
Gboxin 是一种氧化磷酸化抑制剂,可靶向抑制胶质母细胞瘤生长,还抑制 F0F1 ATP 合成,具有抗肿瘤活性。
T40862 Fludarabine triphosphate

三磷酸氟达拉滨,F-ara-ATP

Others Others
Fludarabine triphosphate (F-ara-ATP), the cytotoxic metabolite of Fludarabine phosphate , inhibits ribonucleotide reductase and DNA polymerase and ultimately leads to cellular apoptosis.
T83818 Isoguanosine-5'-O-triphosphate sodium

2-Hydroxyadenosine 5’-triphosphate,2-hydroxy ATP,isoGTP

Others Others
Isoguanosine-5'-O-triphosphate是guanosine 5'-triphosphate(GTP)的一个异构体且是crotonoside的磷酸化形式。与GTP不同,Isoguanosine-5'-O-triphosphate不促进微管组装。在逆转录酶实验中,Isoguanosine-5'-O-triphosphate(2 mM)能抑制转录并诱导T到C的突变。它已被用于确定phosphofructokinase和mutT homolog 1(MTH1)的底物特异性。
T40456 8-Bromoadenosine 5'-triphosphate tetrasodium

8-Br-ATP tetrasodium,8-Bromoadenosine 5'-triphosphate tetrasodium

Others Others
8-Bromoadenosine 5'-triphosphate tetrasodium (8-Br-ATP tetrasodium) is a tetrasodium ATP analogue, serving as a vital element for energy storage and metabolic processes in living organisms. ATP, a central component in vivo, plays a critical role in these functions.
T38511 AWL-II-38.3

Ephrin Receptor Tyrosine Kinase/Adaptors
AWL-II-38.3 is a highly effective inhibitor of EphA3, a receptor for ephrin-A. It demonstrates potent kinase inhibitory activity against EphA3 and does not show significant cellular activity against Src-family kinases or b-raf [1] [2].
T83830 2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate sodium

2′-fluoro-2′-deoxy ATP,AfTP,2'-fluoro dATP

Others Others
2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate是ATP的一种氟代衍生物,ATP是细胞代谢必需的能量底物。它抑制E. coli RNA聚合酶(Ki = 200 µM)。
T15385 Glibornuride

Potassium Channel Membrane transporter/Ion channel
Glibornuride 是对 ATP 敏感的 K+通道 (KATP 通道) 阻滞剂,pKi 为 5.75。Glibornuride 显示抗糖尿病活性。
T9626 Cycloleucine

NMDAR Neuroscience
Cycloleucine 是 NMDA 受体相关甘氨酸受体的拮抗剂,Ki 为 600 μM。Cycloleucine 也是 S-腺苷甲硫氨酸介导的甲基化的竞争性抑制剂,具有抗焦虑和细胞抑制作用。
T7424 NDI-091143

ATP Citrate Lyase Metabolism
NDI-091143 是高亲和力人 ATP 柠檬酸裂解酶抑制剂,其IC50为 2.1 nM (ADP-Glo 分析),Ki 为 7.0 nM,Kd 为 2.2 nM。它能够稳定柠檬酸盐域中的大构象变化,间接抑制柠檬酸的结合和识别,进而抑制ACLY 催化变构反应。
T7545 6-Aminonicotinamide

Others Others
6-Aminonicotinamide 是一种竞争性 NADP+依赖性酶,是一种烟酰胺抗代谢药,葡萄糖 6-磷酸脱氢酶抑制剂 (Ki=0.46 μM)。 它干扰糖酵解,导致 ATP 耗竭,并与 DNA 交联化学疗法药物,如Cisplatin,协同杀死癌细胞。
T16861 SB 204990

ATP Citrate Lyase Metabolism
SB 204990是一种有效的、特异性 ATP 柠檬酸裂解酶抑制剂。
T8535 GAK inhibitor 49

Serine/threonin kinase Cell Cycle/Checkpoint; Metabolism
GAK inhibitor 49 是 ATP 竞争性的细胞周期蛋白 G 相关激酶选择性抑制剂,Ki=0.54 nM,细胞 IC50=56 nM。它也具有与 RIPK2 结合的能力。

化合物

α,β-Methylene ATP trisodium
Cat.No: T13541
Synonym:
Target: P2X Receptor
ATP synthase inhibitor 1
Cat.No: T10404
Synonym:
Target: ATPase
BRM/BRG1 ATP Inhibitor-2
Cat.No: T60032
Synonym:
Target: Epigenetic Reader Domain
ATPγS tetralithium salt
Cat.No: T22592
Synonym: ATP-gamma-S tetralithium salt
Target: PERK
BRM/BRG1 ATP Inhibitor-1
Cat.No: T10616
Synonym:
Target: Epigenetic Reader Domain
8-Bromo-ATP
Cat.No: T39891
Synonym: 8-Bromoadenosine 5'-triphosphate,8-Bromo-ATP,8-Br-ATP
Target: Others
8-Azido-ATP
Cat.No: T40616
Synonym: 8-Azidoadenosine 5'-triphosphate,8-N3-ATP,8-Azido-ATP
Target: Others
ATP dimagnesium
Cat.No: T75325
Synonym:
Target: Others
8-NH2-ATP
Cat.No: T40455
Synonym: 8-Aminoadenosine-5'-O-triphosphate,8-NH2-ATP
Target: Others
2'-NH2-ATP
Cat.No: T40696
Synonym: 2'-NH2-ATP,2'-Amino-2'-deoxyadenosine-5'-triphosphate
Target: Others
Mtb ATP synthase-IN-1
Cat.No: T60877
Synonym:
Target: ATPase
2-Methylthio-ATP tetrasodium
Cat.No: T22496
Synonym: 2-Methylthioadenosine triphosphate tetrasodium salt,2-methylthio-atp-tetrasodium
Target: Others
ATP-polyamine-biotin
Cat.No: T17454
Synonym:
Target: Others
α,β-Methylene-ATP dilithium
Cat.No: T38444
Synonym:
Target: Others
ATP-Red 1
Cat.No: T18917
Synonym:
Target: Others
2',3'-Dialdehyde ATP
Cat.No: T69111
Synonym:
Target: Others
DMNPE-caged ATP diammonium salt
Cat.No: T22738
Synonym:
Target: Others
3'-Deoxy-3'-amino-ATP
Cat.No: T40522
Synonym:
Target: Others
TNP-ATP triethylammonium salt
Cat.No: TP2297
Synonym:
Target: Others
ATP ditromethamine
Cat.No: T75326
Synonym:
Target: Others
6-Me-ATP
Cat.No: T74033
Synonym:
Target: Others
TNP-ATP sodium
Cat.No: T83802
Synonym:
Target:
ATP Synthesis-IN-2
Cat.No: T82944
Synonym:
Target: Others
3′-Acetate-ATP
Cat.No: T79586
Synonym:
Target: Others
2-Chloroadenosine 5-triphosphate sodium
Cat.No: T84928
Synonym: 2-chloro ATP
Target: Others
Oxidized ATP trisodium salt
Cat.No: T78639
Synonym: oATP trisodium salt
Target: P2X Receptor
ATP Synthesis-IN-1
Cat.No: T82945
Synonym:
Target: Others
8-NH2-ATP tetrasodium
Cat.No: T84731
Synonym: 8-Aminoadenosine-5'-O-triphosphate tetrasodium
Target: Others
α,β-Methylene-ATP
Cat.No: T72590
Synonym:
Target: Others
ATP synthase inhibitor 2
Cat.No: T61649
Synonym:
Target: Others
8-Chloroadenosine-5'-triphosphate sodium
Cat.No: T83786
Synonym: 8-chloro ATP
Target: Others
6-Me-ATP trisodium
Cat.No: T74034
Synonym:
Target: Others
Sp-Adenosine-5'-O-(1-thiotriphosphate) sodium
Cat.No: T83808
Synonym: Sp-ATP-α-S
Target: Others
Rp-Adenosine-5'-O-(1-thiotriphosphate) sodium
Cat.No: T83807
Synonym: Rp-ATP-α-S
Target: Others
2'(3')-O-Anthraniloyladenosine-5'-O-triphosphate sodium
Cat.No: T83811
Synonym: 2'(3')-ANT-ATP
Target:
BRM/BRG1 ATP Inhibitor-3
Cat.No: T72257
Synonym:
Target: Others
ATP synthase inhibitor 2 TFA
Cat.No: T79004
Synonym:
Target: Others
BRM/BRG1 ATP Inhibitor-4
Cat.No: T72258
Synonym:
Target: Others
Gboxin
Cat.No: T15373
Synonym:
Target: ATPase, Mitochondrial Metabolism
Fludarabine triphosphate
Cat.No: T40862
Synonym: 三磷酸氟达拉滨,F-ara-ATP
Target: Others
Isoguanosine-5'-O-triphosphate sodium
Cat.No: T83818
Synonym: 2-Hydroxyadenosine 5’-triphosphate,2-hydroxy ATP,isoGTP
Target: Others
8-Bromoadenosine 5'-triphosphate tetrasodium
Cat.No: T40456
Synonym: 8-Br-ATP tetrasodium,8-Bromoadenosine 5'-triphosphate tetrasodium
Target: Others
AWL-II-38.3
Cat.No: T38511
Synonym:
Target: Ephrin Receptor
2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate sodium
Cat.No: T83830
Synonym: 2′-fluoro-2′-deoxy ATP,AfTP,2'-fluoro dATP
Target: Others
Glibornuride
Cat.No: T15385
Synonym:
Target: Potassium Channel
Cycloleucine
Cat.No: T9626
Synonym:
Target: NMDAR
NDI-091143
Cat.No: T7424
Synonym:
Target: ATP Citrate Lyase
6-Aminonicotinamide
Cat.No: T7545
Synonym:
Target: Others
SB 204990
Cat.No: T16861
Synonym:
Target: ATP Citrate Lyase
GAK inhibitor 49
Cat.No: T8535
Synonym:
Target: Serine/threonin kinase
Cat. No. Product Name Target Signaling Pathways
T20089 ATP

Atipi,ATP disodium salt hydrate,Triphosphoric acid adenosine ester,Ara-ATP,Triphosphaden,Adenosine triphosphate;Ara-ATP,Adenosine triphosphate

Endogenous Metabolite Metabolism
ATP (Adenosine triphosphate) 可为细胞提供能量,参与整体能量平衡,维持细胞内稳态。ATP 可以通过与特异性嘌呤能受体的相互作用充当细胞外信号分子,以介导神经传递、炎症、细胞凋亡和骨重塑等多种过程。
T2812 ATP disodium salt hydrate

ATP disodium,ATP disodium salt,Adenosine disodium triphosphate,三磷酸腺苷二钠盐

Others; Endogenous Metabolite Metabolism; Others
ATP disodium salt hydrate (Adenosine disodium triphosphate) 是体内能量储存和代谢的重要物质,为代谢提供能量,同时在细胞中作为辅酶发挥作用。同时,它是也是免疫和炎症中重要的内源性信号分子。
T1352 ATP disodium salt

Adenosine 5'-triphosphate disodium salt,三磷酸腺苷二钠,ATP,ATP disodium,腺苷-5'-三磷酸二钠盐,Adetide,Adenosine-Triphosphate,Disodium adenosine triphosphate

P2X Receptor; Endogenous Metabolite Membrane transporter/Ion channel; Metabolism; Neuroscience
ATP disodium salt (Adenosine-Triphosphate) 是体内能量储存的重要物质,为代谢提供能量,同时在细胞中作为辅酶发挥作用。Adenosine 5'-triphosphate disodium salt 也是免疫和炎症中重要的内源性信号分子。
T64980 ATP disodium trihydrate

Adenosine-5'-triphosphate disodium trihydrate

Endogenous Metabolite Metabolism
ATP disodium trihydrate (Adenosine-5'-triphosphate disodium trihydrate) 是体内能量储存和代谢的重要物质,是免疫和炎症中重要的内源性信号分子,可为机体代谢提供能量,同时在细胞中作为辅酶发挥作用。
T40526 ATP dipotassium

腺苷三磷酸二钾盐,Adenosine5'-triphosphatedipotassium

Others Others
ATP dipotassium (Adenosine 5'-triphosphate dipotassium) is a vital compound involved in energy storage and metabolism within living organisms. It plays a crucial role in supplying metabolic energy for driving pumps and acts as a coenzyme in cellular processes. Additionally, ATP dipotassium functions as a significant endogenous signaling molecule contributing to immunity and inflammation.
T11590 (-)-Hydroxycitric acid

Garcinia acid,(-)-羟基柠檬酸

ATP Citrate Lyase Metabolism
(-)-Hydroxycitric acid (Garcinia acid) 是Garcinia cambogia 果皮中的主要酸。它是 ATP 柠檬酸裂解酶的竞争性抑制剂,能够抑制脂肪酸的合成,减少脂肪生成,控制食物摄入,从而减轻体重。
T6323 Oligomycin A

MCH 32,寡霉素A

ATPase; Antibiotic; Antifungal Membrane transporter/Ion channel; Microbiology/Virology
Oligomycin A (MCH 32) 属于天然产物,是一种线粒体 F0F1-ATPase 抑制剂 (Ki=1 μM)。Oligomycin A 可以抑制线粒体氧化磷酸化,诱导细胞凋亡。Oligomycin A 具有抗真菌活性。
T11589 Hydroxycitric acid tripotassium hydrate

柠檬酸钾一水合物,三水合钾柠檬酸,Potassium citrate monohydrate

ATP Citrate Lyase; HIF/HIF Prolyl-Hydroxylase; HIF Angiogenesis; Chromatin/Epigenetic; Metabolism
Hydroxycitric acid tripotassium hydrate (Potassium citrate monohydrate) 是一种藤黄果的主要活性成分,也是一种柠檬酸的衍生物。它可竞争性抑制柠檬酸裂解酶 (ATP citrate lyase) ,并具有减肥作用。它有效抑制结石形成,并抑制HIF,具有抗氧化,抗炎和抗肿瘤活性。
T12045 (-)-Hydroxycitric acid lactone

藤黄内酯,Garcinia lactone

ATP Citrate Lyase Metabolism
(-)-Hydroxycitric acid lactone (Garcinia lactone) 是一种有效的 ATP-柠檬酸裂解酶抑制剂,能够催化柠檬酸盐线粒体外裂解为草酰乙酸和乙酰辅酶 A,限制了脂肪酸合成所需乙酰辅酶 A 单位的可用性。它是一种减肥药,是一种广受欢迎的减肥食品补充剂。
T3S0156 Atractyloside potassium salt

Atractyloside Dipotassium Salt,苍术苷钾盐,苍术苷二钾盐

Others Others
Atractyloside potassium salt (Atractyloside Dipotassium Salt) 是一种从苍术果实中分离出得到的二萜苷类化合物,具有毒性。它能抑制大鼠心脏线粒体膜的氯离子通道。它是高效、特异性的线粒体 ADP/ATP 转运 (ADP/ATP transport) 抑制剂。
T5544 2-Furoic acid

Furan-2-carboxylic acid,糠酸

Anti-infection; ATP Citrate Lyase; Endogenous Metabolite; Acyltransferase Metabolism; Microbiology/Virology
2-Furoic acid (Furan-2-carboxylic acid) 2-Furoic acid 能够降低血清中胆固醇和甘油三酯的水平,具有抗血脂作用。
T0256 Citric acid trilithium salt tetrahydrate

Lithium citrate tribasic tetrahydrate,柠檬酸三锂盐四水合物,Trilithium citrate tetrahydrate

Dehydrogenase; GSK-3; HIF/HIF Prolyl-Hydroxylase; Antibacterial; GluR Chromatin/Epigenetic; Metabolism; Microbiology/Virology; Neuroscience; PI3K/Akt/mTOR signaling; Stem Cells
Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) 是一种用于治疗精神疾病的药物。它也是一种医药和建筑材料, 可用于氨基酸定量分析时的梯度洗脱。
T3981 Acacetin

4'-Methoxyapigenin,金合欢素,5,7-Dihydroxy-4'-methoxyflavone,Linarigenin

Apoptosis; IAP; COX; Autophagy Apoptosis; Autophagy; Immunology/Inflammation; Neuroscience
Acacetin (5,7-Dihydroxy-4'-methoxyflavone) 是一种来自狗舌草的口服有效类黄酮。它停在 PI3Kγ 的 ATP 结合口袋中,可导致癌细胞周期停滞,并诱导细胞凋亡和自噬。它有抗癌和抗炎活性,有潜力研究疼痛相关疾病。
TN2019 Orobol

3'-Hydroxygenistein,3’,4’,5,7-tetrahydroxy-isoflavon,3',4',5,7-四羟基异黄酮

BCL; Caspase; PI3K Apoptosis; PI3K/Akt/mTOR signaling; Proteases/Proteasome
Orobol (3’,4’,5,7-tetrahydroxy-isoflavon) 是酪氨酸特异性蛋白激酶和磷脂酰肌醇转换的抑制剂。Orobol 抑制 PI3K,对 PI3K α/β/γ/K/δ 的 IC50 为 3.46-5.27 μM。 Orobol 具有抗皮肤老化和抗肥胖的作用。
T40426 Cytidine 5'-diphosphate trisodium salt

CDP,胞苷5'-二磷酸三钠盐水合物,胞苷-5-二磷酸三钠盐,胞苷-5'-二磷酸三钠盐

Others Others
Cytidine 5'-diphosphate trisodium salt (CDP) 可通过尿苷单磷酸激酶 (UMPK) 催化将磷酸基从 ATP 转移到胞苷一磷酸 (CMP) 生成用于合成 DNA 和 RNA 的胞苷三磷酸。
T7475 S-Adenosyl-L-methionine

AdoMet,Ademetionine,SAMe,S-Adenosyl methionine,S-腺苷-L-蛋氨酸

Others; Endogenous Metabolite Metabolism; Others
S-Adenosyl-L-methionine (Ademetionine) 是一种具有有效的抗抑郁和减轻疼痛作用的膳食补充剂,是通过蛋氨酸腺苷转移酶的作用由蛋氨酸和 ATP 内源性生产的,是一种重要的口服具有活力的甲基供体,能够用于肝病和骨关节炎的研究。
T8170 Carboxyatractyloside

羧基苍术苷,Gummiferin,Carboxyatractyloside tripotassium salt

Others Others
Carboxyatractyloside (Carboxyatractyloside tripotassium salt) tripotassium salt 是一种 ADP/ATP 载体蛋白 (ADP/ATP carrier) 抑制剂,抑制线粒体 ADP/ATP 的转运。它是一种具有毒性的天然产物,
T0465 Ellagic acid

鞣花酸,Gallogen,Elagostasine

Hedgehog/Smoothened; Casein Kinase; Reactive Oxygen Species; Topoisomerase; Endogenous Metabolite; PKA; Syk; PKC; Carbonic Anhydrase Angiogenesis; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; GPCR/G Protein; Immunology/Inflammation; Metabolism; NF-κB; Stem Cells; Tyrosine Kinase/Adaptors
Ellagic acid (Gallogen) 是从 Eucalyptus maculata Hook 和 E. Hemipholia F. Muell 的 kino 中分离出来的稠合四环天然产物,是一种有效的,ATP 竞争性的CK2抑制剂,IC50和Ki 值分别为 40 nM 和 20 nM。
T3S0870 Paederosidic acid methyl ester

鸡屎藤苷酸甲酯,紫草酸甲酯

ATPase; Potassium Channel; NO Synthase Immunology/Inflammation; Membrane transporter/Ion channel
Paederosidic acid methyl ester 是 ATP 敏感的 K+channel 通道激活剂,分离自 P. scandens。它通过激活脑中和脊髓水平中 ATP 敏感型 K+通道提高了痛觉阈值,表现出显著的中枢缓解疼痛活性。
T4888 Phosphocreatine disodium hydrate

磷酸肌酸二钠盐,Phosphocreatine disodium salt hydrate

Others; Endogenous Metabolite Metabolism; Others
Phosphocreatine disodium hydrate 是内源性代谢产物的一种。
T3419 Chelerythrine chloride

白屈菜红碱,盐酸白屈菜红碱

Apoptosis; BCL; PKC; Autophagy Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling
Chelerythrine chloride 是一种可渗透细胞的蛋白激酶 C 抑制剂,对磷酸盐受体具有竞争性,而对 ATP 是非竞争性的。它诱导细胞凋亡和自噬。
T22300 Creatine monohydrate

Methylguanidoacetic acid monohydrate,一水肌酸

Others; Endogenous Metabolite Metabolism; Others
Creatine monohydrate (Methylguanidoacetic acid monohydrate) 是磷酸原能量系统的关键参与者,尤其是在肌肉和大脑中。 Creatine monohydrate 是高强度、短期活动中 ATP 的主要来源。
T21494 Oligomycin

寡霉素

HIF Angiogenesis; Chromatin/Epigenetic
Oligomycin 是一种抗真菌抗生素,是 H+-ATP 合成酶的抑制剂。Oligomycin 能够阻断氧化磷酸化和电子传递链。Oligomycin 对缺氧性肿瘤细胞 HIF-1alpha 表达具有抑制作用。
T6680 Staurosporine

Antibiotic AM-2282,星形孢菌素,AM-2282,CGP 41251,星孢菌素

Apoptosis; PKA; Antibacterial; Antibiotic; Src; PKC; Antifungal Angiogenesis; Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; Microbiology/Virology; Tyrosine Kinase/Adaptors
Staurosporine (AM-2282) 是一种蛋白激酶抑制剂,对 PKC、PKA、c-Fgr、Phosphorylase kinase 和 TAOK2 均有抑制活性 (IC50=6/15/2/3/3000 nM),具有 ATP 竞争性和非选择性。Staurosporine 也可以诱导凋亡。
T20003 Acridone

Antibacterial; ABC Membrane transporter/Ion channel; Microbiology/Virology
Acridone 具有抗菌、抗疟、抗病毒和抗肿瘤活性。它可诱导细胞凋亡,抑制 ABCG2 蛋白,并调节激素水平。
T4739 Sodium creatine phosphate dibasic tetrahydrate

磷酸肌酸二钠盐,Creatine phosphate disodium salt tetrahydrate

Others; Endogenous Metabolite Metabolism; Others
Sodium creatine phosphate dibasic tetrahydrate (Creatine phosphate disodium salt tetrahydrate) 主要存在于脊椎动物的骨骼肌中,是测定肌酸激酶的底物,能够用于骨骼肌收缩过程中 ATP 的再生。
T0064 Adenine

Vitamin B4,腺嘌呤,6-Aminopurine

DNA/RNA Synthesis; Endogenous Metabolite; AChR Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Neuroscience
Adenine (6-Aminopurine) 是一种嘌呤衍生物,是一种核碱基。它在细胞呼吸、以富含能量的 ATP 和 NAD 和 FAD 的形式和蛋白质合成作用,作为 DNA 和 RNA 的化学成分。
Fr14207 (-)-Isopulegol

Others Others
(-)-Isopulegol 具有抗氧化和神经活性特性。它还具有由异胡薄荷醇诱导的胃保护作用,似乎至少部分由内源性前列腺素介导,K+ATP 通道开放和与 GSH 相关的抗氧化特性增加。
T17143 Toyocamycin

丰加霉素,Vengicide

Apoptosis; Others; IRE1; Antibiotic; Antifungal Apoptosis; Cell Cycle/Checkpoint; Microbiology/Virology; Others
Toyocamycin (Vengicide) 是放线菌类产生的腺苷类似物,为 X 盒结合蛋白 1 (XBP1) 抑制剂,抑制 IRE1α 诱导的 ATP 依赖性 XBP1 mRNA 的断裂,IC50值为 80 nM。它还诱导凋亡。
T25192 Butyrolactone I

Olomoucin,丁酸内酯I

CDK Cell Cycle/Checkpoint
Butyrolactone I (Olomoucin) 是 CDK 和 cdc2 激酶家族的 ATP 竞争性抑制剂。 Butyrolactone I 在非小细胞肺、小细胞肺和前列腺癌细胞系中显示出抗肿瘤作用。
T3313 D-Luciferin

Firefly luciferin,D-萤光素,D-荧光素,D-(-)-Luciferin

Others Others
D-Luciferin (D-(-)-Luciferin) 是一种萤光素酶的底物,能够催化生物发光昆虫产生典型的黄绿光。
TL0009 coniferin

Coniferoside,松柏苷,Abietin

Others; Antifungal Microbiology/Virology; Others
Coniferin (Abietin) 是一种松柏醇中的葡萄糖苷。它抑制真菌生长和黑化反应,具有 ATP 依赖性转运活性并具有抗氧化作用。
T3929 Kaurenoic acid

Kauren-19-Oic Acid,异贝壳杉烯酸,kaurenoate,kaur-16-en-18-oic acid

Others Others
Kaurenoic acid (kaurenoate) 是一种二萜,来源于 Sphagneticola trilobata 中,可以抑制细胞因子的产生和激活 NO–cyclic GMP–PKG–ATP- 敏感型钾通道信号通路,并抑制炎症疼痛。
T5079 Adenosine 5'-diphosphate sodium salt

腺苷-5‘-二磷酸钠盐,Adenosine-5'-diphosphate trisodium salt,ADP sodium salt

Others; Endogenous Metabolite Metabolism; Others
Adenosine 5'-diphosphate sodium salt (ADP sodium salt) 是一种核苷二磷酸,是一种 ATP 酶对 ATP 去磷酸化的产物。它通过在 P2T-嘌呤受体上的作用诱导人血小板聚集并抑制刺激的腺苷酸环化酶。
TN4883 Quinine sulfate dihydrate

奎宁树

Others Others
Quinine sulfate dihydrate 在钾通道阻滞剂中起主要作用。它也被用作抗疟疾、抗胆碱能、抗高血压和降糖药。它抑制线粒体atp 调节的钾通道。它也被用来研究生物结晶血红素,血红素,在疟疾寄生虫的代谢和研究血红素(FP)复合物的毒性。
T1723 Adenosine 5'-diphosphate

腺苷5'-二磷酸,Adenosine diphosphate,adenosine pyrophosphate,ADP

Endogenous Metabolite Metabolism
Adenosine 5'-diphosphate (ADP) 是一种嘌呤核糖核苷5'-二磷酸,是 ATPATP 酶作用下去磷酸化的产物。Adenosine 5'-diphosphate (adenosine pyrophosphate) 可诱导人血小板聚集并通过作用于P2T-嘌呤受体抑制受刺激的腺苷酸环化酶。
T5067 Flavin adenine dinucleotide disodium salt

Flavin Adenine Dinucleotide Disodium,黄素腺嘌呤二核苷酸二钠,FAD sodium salt,FAD-Na2

Others; Endogenous Metabolite Metabolism; Others
Flavin adenine dinucleotide disodium salt (FAD sodium salt) 是一种辅酶,作用是促进细胞氧化还原反应中黄素酶的电子转移。
T4786 D-Ribose(mixture of isomers)

D-Ribose,D-(-)-Ribose,D-(-)-核糖

Others; Endogenous Metabolite Metabolism; Others
D-Ribose(mixture of isomers) (D-(-)-Ribose) 是 ATP 的糖部分,可作为能量增强剂,被广泛用作慢性疲劳综合症和心肌能量代谢的代谢疗法补充剂。它在蛋白质糖化中具有特性,能够 RAGE 依赖的方式诱导 NF-Κb 炎症。
T4883 Creatine

Methylguanidoacetic acid,肌酸

Endogenous Metabolite Metabolism
Creatine (Methylguanidoacetic acid) 是一种内源性氨基酸代谢物,在细胞能量中发挥重要作用,尤其是在肌肉和大脑中。
T4897 Inosine-5'-triphosphate trisodium salt

ITP,肌苷-5'-三磷酸三钠盐,三磷酸肌苷三钠盐,Inosine 5'-triphosphate trisodium salt

Others; Endogenous Metabolite Metabolism; Others
Inosine-5'-triphosphate trisodium salt (ITP) 是三磷酸核苷,能够作为 ATPases 和 GTPases 的底物。
T10857 Coenzyme A

Endogenous Metabolite Metabolism
Coenzyme A 是所有活细胞中必需的辅助因子,由泛酸,三磷酸腺苷和半胱氨酸合成的。Coenzyme A 与过氧化物酶 5 共价结合导致其过氧化物酶活性完全抑制,通过 DTT 还原能够逆转。Coenzyme A 及其硫酯衍生物是主要分解代谢,合成代谢途径和基因表达调控的关键参与者。
T3375 Verbascoside

毛蕊花苷,麦角甾苷,Kusaginin,Acteoside,TJC160

Apoptosis; PARP; Antibacterial; PKC; p53; HSV Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; Microbiology/Virology
Verbascoside (Kusaginin) 是从Lantana camara 中得到的糖苷类物质,是具有ATP 竞争性的PKC 抑制剂,IC50值为 25 µM,它还有抗炎,抗肿瘤,抗神经性疼痛等作用。
T3228 Fosfructose

D-fructose-1,6-diphosphate,Betulanonaprenol,4937-84-2,Diphosphofructose,二磷酸果糖,Fructose 1,6-diphosphate,D-fructofuranose 1,6-bisphosphate,Esafosfan

Others; Endogenous Metabolite Metabolism; Others
D-fructose-1,6-diphosphate 是一种细胞保护性的天然糖磷酸盐,Fosfructose 通过刺激无氧糖酵解起作用,其在缺血条件下产生三磷酸腺苷,有潜力用于心血管缺血,镰状细胞性贫血和哮喘的研究。
T6354 (+)-Usnic acid

D-Usnic Acid,松萝酸,(+)-Usniacin,(+)-地衣酸

Antiviral; Antibacterial; mTOR Immunology/Inflammation; Microbiology/Virology; PI3K/Akt/mTOR signaling
(+)-Usnic acid (D-Usnic Acid) 是地衣中的二苯并呋喃衍生物,可结合 mTOR 的 ATP 结合口袋,抑制 mTORC1/2的活性。它诱导自噬,有抗菌和抗肿瘤活性。
T4737 2'-Deoxyadenosine-5'-monophosphate

D-AMP,2′-脱氧腺苷-5′-单磷酸,2'-Deoxyadenosine 5'-monophosphate,2'-脱氧腺苷-5'-单磷酸

Others; Endogenous Metabolite Metabolism; Others
2'-Deoxyadenosine-5'-monophosphate (D-AMP) 是一种存在于 DNA 中的脱氧核糖核苷酸,是一种核酸 AMP 衍生物。它能够用于研究 DNA 合成和 DNA 损伤过程中基于腺苷的相互作用。
T4826 L-Histidine monohydrochloride monohydrat

Others; Endogenous Metabolite Metabolism; Others
L-Histidine monohydrochloride monohydrat 是一种 α-氨基酸。 L-异构体是 22 种蛋白质氨基酸之一,即蛋白质的组成部分。
T8061 Citronellal

(±)-Citronellal,香茅醛

Others Others
Citronellal ((±)-Citronellal) 是多种芳香植物精油的单萜烯,具有促进睡眠、安定和抗伤害的作用。它可以降低机械伤害感受,且部分通过 NO-cGMP-ATP 敏感型 K⁺渠道通道介导的。
T6225 Adenine hydrochloride

Adenine HCl,腺嘌呤盐酸盐,6-Aminopurine hydrochloride

DNA/RNA Synthesis; Endogenous Metabolite Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
Adenine hydrochloride (6-Aminopurine hydrochloride) 是一种嘌呤,是一种核碱基。它在细胞呼吸、以富含能量的 ATP 和 NAD 和 FAD 的形式和蛋白质合成作用,作为 DNA 和 RNA 的化学成分。
T8270 Deserpidine

地舍平,Harmonyl

RAAS Endocrinology/Hormones
Deserpidine (Harmonyl) 是从 Rauwolfia canescens 的根中分离的生物碱。Deserpidine 与 Reserpine 相关。Deserpidine 是竞争性血管紧张素转化酶抑制剂,可以被用作抗高血压药以及镇定剂。Deserpidine 还减少了肾上腺皮质血管紧张素 II 诱导的醛固酮分泌。
T36390 Sodium oleate

Oleic acid sodium salt,Sodium oleate,cis-9-Octadecenoic acid sodium salt

ATPase Membrane transporter/Ion channel
Sodium oleate (cis-9-Octadecenoic acid sodium salt) (Oleic acid sodium) 是人脂肪细胞和其他组织中最常见的单不饱和脂肪酸钠盐。Sodium oleate 是一种 Na+/K+ ATP 酶激活剂。
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天然产物

ATP
Cat.No: T20089
Synonym: Atipi,ATP disodium salt hydrate,Triphosphoric acid adenosine ester,Ara-ATP,Triphosphaden,Adenosine triphosphate;Ara-ATP,Adenosine triphosphate
Target: Endogenous Metabolite
ATP disodium salt hydrate
Cat.No: T2812
Synonym: ATP disodium,ATP disodium salt,Adenosine disodium triphosphate,三磷酸腺苷二钠盐
Target: Others, Endogenous Metabolite
ATP disodium salt
Cat.No: T1352
Synonym: Adenosine 5'-triphosphate disodium salt,三磷酸腺苷二钠,ATP,ATP disodium,腺苷-5'-三磷酸二钠盐,Adetide,Adenosine-Triphosphate,Disodium adenosine triphosphate
Target: P2X Receptor, Endogenous Metabolite
ATP disodium trihydrate
Cat.No: T64980
Synonym: Adenosine-5'-triphosphate disodium trihydrate
Target: Endogenous Metabolite
ATP dipotassium
Cat.No: T40526
Synonym: 腺苷三磷酸二钾盐,Adenosine5'-triphosphatedipotassium
Target: Others
(-)-Hydroxycitric acid
Cat.No: T11590
Synonym: Garcinia acid,(-)-羟基柠檬酸
Target: ATP Citrate Lyase
Oligomycin A
Cat.No: T6323
Synonym: MCH 32,寡霉素A
Target: ATPase, Antibiotic, Antifungal
Hydroxycitric acid tripotassium hydrate
Cat.No: T11589
Synonym: 柠檬酸钾一水合物,三水合钾柠檬酸,Potassium citrate monohydrate
Target: ATP Citrate Lyase, HIF/HIF Prolyl-Hydroxylase, HIF
(-)-Hydroxycitric acid lactone
Cat.No: T12045
Synonym: 藤黄内酯,Garcinia lactone
Target: ATP Citrate Lyase
Atractyloside potassium salt
Cat.No: T3S0156
Synonym: Atractyloside Dipotassium Salt,苍术苷钾盐,苍术苷二钾盐
Target: Others
2-Furoic acid
Cat.No: T5544
Synonym: Furan-2-carboxylic acid,糠酸
Target: Anti-infection, ATP Citrate Lyase, Endogenous Metabolite, Acyltransferase
Citric acid trilithium salt tetrahydrate
Cat.No: T0256
Synonym: Lithium citrate tribasic tetrahydrate,柠檬酸三锂盐四水合物,Trilithium citrate tetrahydrate
Target: Dehydrogenase, GSK-3, HIF/HIF Prolyl-Hydroxylase, Antibacterial, GluR
Acacetin
Cat.No: T3981
Synonym: 4'-Methoxyapigenin,金合欢素,5,7-Dihydroxy-4'-methoxyflavone,Linarigenin
Target: Apoptosis, IAP, COX, Autophagy
Orobol
Cat.No: TN2019
Synonym: 3'-Hydroxygenistein,3’,4’,5,7-tetrahydroxy-isoflavon,3',4',5,7-四羟基异黄酮
Target: BCL, Caspase, PI3K
Cytidine 5'-diphosphate trisodium salt
Cat.No: T40426
Synonym: CDP,胞苷5'-二磷酸三钠盐水合物,胞苷-5-二磷酸三钠盐,胞苷-5'-二磷酸三钠盐
Target: Others
S-Adenosyl-L-methionine
Cat.No: T7475
Synonym: AdoMet,Ademetionine,SAMe,S-Adenosyl methionine,S-腺苷-L-蛋氨酸
Target: Others, Endogenous Metabolite
Carboxyatractyloside
Cat.No: T8170
Synonym: 羧基苍术苷,Gummiferin,Carboxyatractyloside tripotassium salt
Target: Others
Ellagic acid
Cat.No: T0465
Synonym: 鞣花酸,Gallogen,Elagostasine
Target: Hedgehog/Smoothened, Casein Kinase, Reactive Oxygen Species, Topoisomerase, Endogenous Metabolite, PKA, Syk, PKC, Carbonic Anhydrase
Paederosidic acid methyl ester
Cat.No: T3S0870
Synonym: 鸡屎藤苷酸甲酯,紫草酸甲酯
Target: ATPase, Potassium Channel, NO Synthase
Phosphocreatine disodium hydrate
Cat.No: T4888
Synonym: 磷酸肌酸二钠盐,Phosphocreatine disodium salt hydrate
Target: Others, Endogenous Metabolite
Chelerythrine chloride
Cat.No: T3419
Synonym: 白屈菜红碱,盐酸白屈菜红碱
Target: Apoptosis, BCL, PKC, Autophagy
Creatine monohydrate
Cat.No: T22300
Synonym: Methylguanidoacetic acid monohydrate,一水肌酸
Target: Others, Endogenous Metabolite
Oligomycin
Cat.No: T21494
Synonym: 寡霉素
Target: HIF
Staurosporine
Cat.No: T6680
Synonym: Antibiotic AM-2282,星形孢菌素,AM-2282,CGP 41251,星孢菌素
Target: Apoptosis, PKA, Antibacterial, Antibiotic, Src, PKC, Antifungal
Acridone
Cat.No: T20003
Synonym:
Target: Antibacterial, ABC
Sodium creatine phosphate dibasic tetrahydrate
Cat.No: T4739
Synonym: 磷酸肌酸二钠盐,Creatine phosphate disodium salt tetrahydrate
Target: Others, Endogenous Metabolite
Adenine
Cat.No: T0064
Synonym: Vitamin B4,腺嘌呤,6-Aminopurine
Target: DNA/RNA Synthesis, Endogenous Metabolite, AChR
(-)-Isopulegol
Cat.No: Fr14207
Synonym:
Target: Others
Toyocamycin
Cat.No: T17143
Synonym: 丰加霉素,Vengicide
Target: Apoptosis, Others, IRE1, Antibiotic, Antifungal
Butyrolactone I
Cat.No: T25192
Synonym: Olomoucin,丁酸内酯I
Target: CDK
D-Luciferin
Cat.No: T3313
Synonym: Firefly luciferin,D-萤光素,D-荧光素,D-(-)-Luciferin
Target: Others
coniferin
Cat.No: TL0009
Synonym: Coniferoside,松柏苷,Abietin
Target: Others, Antifungal
Kaurenoic acid
Cat.No: T3929
Synonym: Kauren-19-Oic Acid,异贝壳杉烯酸,kaurenoate,kaur-16-en-18-oic acid
Target: Others
Adenosine 5'-diphosphate sodium salt
Cat.No: T5079
Synonym: 腺苷-5‘-二磷酸钠盐,Adenosine-5'-diphosphate trisodium salt,ADP sodium salt
Target: Others, Endogenous Metabolite
Quinine sulfate dihydrate
Cat.No: TN4883
Synonym: 奎宁树
Target: Others
Adenosine 5'-diphosphate
Cat.No: T1723
Synonym: 腺苷5'-二磷酸,Adenosine diphosphate,adenosine pyrophosphate,ADP
Target: Endogenous Metabolite
Flavin adenine dinucleotide disodium salt
Cat.No: T5067
Synonym: Flavin Adenine Dinucleotide Disodium,黄素腺嘌呤二核苷酸二钠,FAD sodium salt,FAD-Na2
Target: Others, Endogenous Metabolite
D-Ribose(mixture of isomers)
Cat.No: T4786
Synonym: D-Ribose,D-(-)-Ribose,D-(-)-核糖
Target: Others, Endogenous Metabolite
Creatine
Cat.No: T4883
Synonym: Methylguanidoacetic acid,肌酸
Target: Endogenous Metabolite
Inosine-5'-triphosphate trisodium salt
Cat.No: T4897
Synonym: ITP,肌苷-5'-三磷酸三钠盐,三磷酸肌苷三钠盐,Inosine 5'-triphosphate trisodium salt
Target: Others, Endogenous Metabolite
Coenzyme A
Cat.No: T10857
Synonym:
Target: Endogenous Metabolite
Verbascoside
Cat.No: T3375
Synonym: 毛蕊花苷,麦角甾苷,Kusaginin,Acteoside,TJC160
Target: Apoptosis, PARP, Antibacterial, PKC, p53, HSV
Fosfructose
Cat.No: T3228
Synonym: D-fructose-1,6-diphosphate,Betulanonaprenol,4937-84-2,Diphosphofructose,二磷酸果糖,Fructose 1,6-diphosphate,D-fructofuranose 1,6-bisphosphate,Esafosfan
Target: Others, Endogenous Metabolite
(+)-Usnic acid
Cat.No: T6354
Synonym: D-Usnic Acid,松萝酸,(+)-Usniacin,(+)-地衣酸
Target: Antiviral, Antibacterial, mTOR
2'-Deoxyadenosine-5'-monophosphate
Cat.No: T4737
Synonym: D-AMP,2′-脱氧腺苷-5′-单磷酸,2'-Deoxyadenosine 5'-monophosphate,2'-脱氧腺苷-5'-单磷酸
Target: Others, Endogenous Metabolite
L-Histidine monohydrochloride monohydrat
Cat.No: T4826
Synonym:
Target: Others, Endogenous Metabolite
Citronellal
Cat.No: T8061
Synonym: (±)-Citronellal,香茅醛
Target: Others
Adenine hydrochloride
Cat.No: T6225
Synonym: Adenine HCl,腺嘌呤盐酸盐,6-Aminopurine hydrochloride
Target: DNA/RNA Synthesis, Endogenous Metabolite
Deserpidine
Cat.No: T8270
Synonym: 地舍平,Harmonyl
Target: RAAS
Sodium oleate
Cat.No: T36390
Synonym: Oleic acid sodium salt,Sodium oleate,cis-9-Octadecenoic acid sodium salt
Target: ATPase
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Cat. No. Product Name Species Expression System
TMPY-02483 ATP citrate lyase/ACLY Protein, Human, Recombinant (His)

ATPCL,ACL,ATP citrate lyase,CLATP

Human Baculovirus Insect Cells
ATP citrate lyase, also known as Acly or Acl, is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is composed of two polymer chains which are polypeptides in human. ATP citrate lyase is responsible for catalyzing the conversion of citrate and CoA into acetyl-CoA and oxaloacetate, along with the hydrolysis of ATP. A definitive role for ATP citrate lyase in tumorigenesis has emerged from ATP citrate lyase RNAi and chemical inhibitor studies, show...
TMPH-00524 ATP-dependent DNA helicase dda Protein, Enterobacteria phage T4, Recombinant (His)

ATP-dependent DNA helicase dda,dda,sud

Enterobacteria phage T4 E. coli
DNA helicase that stimulates viral DNA replication and recombination. Plays a role in T4 DNA replication initiation by selecting and activating DNA origins. Acts by dissociating and reassociating with the DNA molecule being unwound. Unwinds DNA as a monomer in a 5'-to-3' direction at a rate of 250 bp/s and can efficiently displace proteins from the DNA. ATP-dependent DNA helicase dda Protein, Enterobacteria phage T4, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. T...
TMPH-00581 ATP-dependent Clp protease adapter protein ClpS Protein, E. coli, Recombinant (His)

yljA,ATP-dependent Clp protease adapter protein Clp...

E. coli E. coli
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. ATP-dependent Clp protease adapter protein ClpS Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 16.2?kDa and the accession number is P0A8Q6.
TMPH-02530 ATP5B Protein, Mouse, Recombinant (His & Myc & SUMO)

ATP synthase F1 subunit beta,Atp5b,Atp...

Mouse E. coli
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain ...
TMPH-00964 ATP5PB Protein, Human, Recombinant (His & Myc)

ATP synthase proton-transporting mitochondrial F(0)...

Human E. coli
ATP5PB Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPH-00966 ATP5F1B Protein, Human, Recombinant (His)

ATP synthase F1 subunit beta,ATP synthase ...

Human P. pastoris (Yeast)
ATP5F1B Protein, Human, Recombinant (His) is expressed in Yeast.
TMPH-00969 ATP5O Protein, Human, Recombinant (GST)

OSCP,ATP5PO,ATP synthase peripheral stalk ...

Human E. coli
ATP5O Protein, Human, Recombinant (GST) is expressed in E. coli.
TMPH-00967 ATP5F1B Protein, Human, Recombinant (His & Myc & SUMO)

ATP5B,ATP synthase F1 subunit beta,ATP...

Human E. coli
ATP5F1B Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli.
TMPH-00965 ATP5F1A Protein, Human, Recombinant (His)

ATP5F1A,ATP5A,ATP synthase subuni...

Human E. coli
ATP5F1A Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-03249 ATP5F1B Protein, Rat, Recombinant (His & Myc)

ATPMB,ATPSB,ATP synthase subunit ...

Rat E. coli
ATP5F1B Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 59.2 kDa and the accession number is P10719.
TMPY-03609 ATP5D Protein, Human, Recombinant (His)

ATP synthase, H+ transporting, mitochondrial F1 com...

Human E. coli
ATP5D is a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase consists of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon...
TMPH-00968 ATP5C1 Protein, Human, Recombinant (His & Myc)

F-ATPase gamma subunit,ATP5C1,ATP...

Human E. coli
ATP5C1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 37.6 kDa and the accession number is P36542.
TMPH-00226 ATPase subunit g Protein, Bovine, Recombinant (His & Myc)

ATP synthase subunit g, mitochondrial,ATP5...

Bovine E. coli
ATPase subunit g Protein, Bovine, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.7 kDa and the accession number is Q28852.
TMPH-00906 SLC25A6 Protein, Human, Recombinant (His & KSI)

ADP,ATP carrier protein 3,SLC25A6,ADP,ATP ...

Human E. coli
SLC25A6 Protein, Human, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 20.2 kDa and the accession number is P12236.
TMPH-00665 RecG Protein, E. coli O157:H7, Recombinant (His & SUMO)

ATP-dependent DNA helicase RecG,recG

E. coli E. coli
Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA). Has a role in constitutive stable DNA replication (CsdR) and R-loop formation.
TMPJ-00462 NADK Protein, Human, Recombinant (His)

Poly(P)/ATP NAD Kinase,NADK,NAD Kinase

Human E. coli
NAD Kinase (NADK) is an enzyme that belongs to the NAD Kinase family. It is a widely expressed enzyme, but it is not detected in skeletal muscle. NADK converts Nicotinamide Adenine Dinucleotide (NAD+) into NADP+, through phosphorylating the NAD+ coenzyme. NADP+ is an essential coenzyme in metabolism and provides reducing power to biosynthetic processes such as fatty acid biosynthesis. The structure of the NADK from the archaean Archaeoglobus fulgidus has been determined.
TMPY-05160 PFKP Protein, Human, Recombinant (His & GST)

PFK-P,PFKF,ATP-PFK,phosphofructokinase, platelet,PF...

Human Baculovirus Insect Cells
PFKP plays a critical role in cell proliferation in breast cancer cells. PFKP is necessary for starvation-mediated autophagy, glycolysis, and EMT, thereby promoting the malignant progression of OSCC. The Snail-PFKP axis plays an important role in cancer cell survival via regulation of glucose flux between glycolysis and PPP.
TMPH-01829 Human Papilloma Virus type 11 (HPV 11) Regulatory Protein E1 (His)

ATP-dependent helicase E1,E1,Replication protein E1

HPV 11 E. coli
Human Papilloma Virus type 11 (HPV 11) Regulatory Protein E1 (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.1 kDa and the accession number is P04014.
TMPH-00574 Adenylate cyclase Protein, E. coli, Recombinant (His)

cyaA,EC:4.6.1.1,Adenylyl cyclase,ATP pyrophosphate-...

E. coli E. coli
Catalyzes the formation of the second messenger cAMP from ATP. Its transcript is probably degraded by endoribonuclease LS (rnlA), decreasing cAMP levels and the negative regulator Crp-cAMP, which then induces its own transcription again.
TMPH-03283 CD39 Protein, Rat, Recombinant (His)

ATP diphosphohydrolase,Entpd1,Nucleoside triphospha...

Rat Baculovirus Insect Cells
In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well.
TMPH-03284 CD39 Protein, Rat, Recombinant (E. coli, His)

Entpd1,ATP-DPH,Ecto-ATP diphosphohydrolase...

Rat E. coli
In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well.
TMPH-03503 Adenylate kinase Protein, Shigella flexneri, Recombinant (His & Myc & SUMO)

ATP-AMP transphosphorylase,AK,Adenylate monophospha...

Shigella flexneri E. coli
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase Protein, Shigella flexneri, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 43.6 kDa and the accession number is Q83M40.
TMPH-00713 Polyphosphate kinase Protein, E. coli, Recombinant (His & Myc)

Polyphosphoric acid kinase,ATP-polyphosphate phosph...

E. coli E. coli
Polyphosphate kinase Protein, E. coli, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 87.7 kDa and the accession number is P0A7B1.
TMPH-00741 Rho Protein, E. coli, Recombinant (His)

Transcription termination factor Rho,ATP-dependent ...

E. coli E. coli
Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template. RNA-dependent NTPase which utilizes all four ribonucleoside triphosphates as substrates. Rho Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 51.0 kDa and the accession number is P0AG30.
TMPH-00408 ClpP Protein, Clostridium botulinum, Recombinant (His & SUMO)

clpP,Endopeptidase Clp,ATP-dependent Clp protease p...

Clostridium botulinum E. coli
ClpP Protein, Clostridium botulinum, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-00904 Adenylate kinase 7 Protein, Human, Recombinant (His)

AK7,ATP-AMP transphosphorylase 7,EC:2.7.4.3,EC:2.7....

Human Baculovirus Insect Cells
Adenylate kinase 7 Protein, Human, Recombinant (His) is expressed in Baculovirus.
TMPH-00582 Endopeptidase Clp Protein, E. coli, Recombinant (His & Myc)

clpP,ATP-dependent Clp protease proteolytic subunit...

E. coli E. coli
Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
TMPH-00981 ABCB1 Protein, Human, Recombinant (His)

Multidrug resistance protein 1,P-glycoprotein 1,ATP...

Human E. coli
ABCB1 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-00980 DHX33 Protein, Human, Recombinant (His)

ATP-dependent RNA helicase DHX33,DEAH box protein 3...

Human E. coli
DHX33 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-01902 DDX60 Protein, Human, Recombinant (His)

Probable ATP-dependent RNA helicase DDX60,DEAD box ...

Human E. coli
Positively regulates DDX58/RIG-I- and IFIH1/MDA5-dependent type I interferon and interferon inducible gene expression in response to viral infection. Binds ssRNA, dsRNA and dsDNA and can promote the binding of DDX58/RIG-I to dsRNA. Exhibits antiviral activity against hepatitis C virus and vesicular stomatitis virus (VSV). DDX60 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.1 kDa and the accession number is Q8IY2...
TMPY-04479 PFKM Protein, Human, Recombinant (His & GST)

ATP-PFK,PFK-1,PFK1,PFKA,PFKX,GSD7,phosphofructokina...

Human Baculovirus Insect Cells
PFK1, also known as PFKM, is a regulatory glycolytic enzyme. PFK1 converts fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through PFK-2) and ADP. It is a muscle-type isozyme. There are three phosphofructokinase isozymes in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Mutations i...
TMPH-00787 BtuD Protein, Halobacterium salinarum, Recombinant

Vitamin B12-transporting ATPase,Cobalamin import

Halobacterium salinarum E. coli
Required for corrinoid utilization. Probably part of the ABC transporter complex BtuCDF involved in cobalamin (vitamin B12) import. Probably responsible for energy coupling to the transport system.
TMPH-00786 BtuD Protein, Halobacterium salinarum, Recombinant (His)

Vitamin B12-transporting ATPase,btuD,Cobalamin impo...

Halobacterium salinarum E. coli
Required for corrinoid utilization. Probably part of the ABC transporter complex BtuCDF involved in cobalamin (vitamin B12) import. Probably responsible for energy coupling to the transport system.
TMPH-00583 Rep Protein, E. coli, Recombinant (GST)

ATP-dependent DNA helicase Rep,rep,DNA 3'-5' helica...

E. coli E. coli
Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.
TMPH-00398 PPK2 Protein, Chlorobium tepidum, Recombinant (His & Myc)

ppk2,ATP-polyphosphate phosphotransferase 2,Polypho...

Chlorobaculum tepidum E. coli
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). PPK2 Protein, Chlorobium tepidum, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.4 kDa and the accession number is O68984.
TMPH-00979 DDX3Y Protein, Human, Recombinant (His & Myc)

DDX3Y,DBY,DEAD box protein 3, Y-chromosomal,ATP-dep...

Human Baculovirus Insect Cells
DDX3Y Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus.
TMPH-00970 ABCD1 Protein, Human, Recombinant (His)

ALD,ATP-binding cassette sub-family D member 1,Adre...

Human E. coli
ABCD1 Protein, Human, Recombinant (His) is expressed in in vitro E. coli expression system.
TMPH-00209 CLPP2 Protein, Borrelia burgdorferi, Recombinant (His & Myc)

clpP-2,Endopeptidase Clp 2,ATP-dependent Clp protea...

Borrelia burgdorferi E. coli
Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
TMPJ-01145 ABCB5 Protein, Human, Recombinant (Trx)

ABCB5 P-gp,ATP-binding cassette sub-family B member...

Human E. coli
ATP-binding cassette sub-family B member 5(ABCB5) is a plasma membrane-spanning protein. ABCB5 is principally expressed in physiological skin and human malignant melanoma. ABCB5 has been suggested to regulate skin progenitor cell fusion and mediate chemotherapeutic drug resistance in stem-like tumor cell subpopulations in human malignant melanoma. It is commonly over-expressed on circulating melanoma tumour cells. Furthermore, the ABCB5+ melanoma- initiating cells were demonstrated to express FL...
TMPH-00976 DDX19A Protein, Human, Recombinant (His & SUMO)

DDX19L,DDX19A,DDX19-like protein,DEAD box protein 19A,AT...

Human E. coli
DDX19A Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-00975 DDX1 Protein, Human, Recombinant (His & Myc)

DBP-RB,DDX1,ATP-dependent RNA helicase DDX1,DEAD bo...

Human E. coli
DDX1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPH-01900 DDX5 Protein, Human, Recombinant (His & Myc)

HELR,RNA helicase p68,HLR1,G17P1,DEAD box protein 5,Probable...

Human E. coli
DDX5 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 74.1 kDa and the accession number is P17844.
TMPH-01998 G3BP1 Protein, Human, Recombinant (His)

ATP-dependent DNA helicase VIII,GAP SH3 domain-bind...

Human E. coli
G3BP1 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-02133 DDX39B Protein, Human, Recombinant (GST)

UAP56,HLA-B-associated transcript 1 protein,DDX39B,ATP

Human E. coli
Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it fun...
TMPH-00978 DDX3X Protein, Human, Recombinant (His & Myc)

DEAD box, X isoform,DEAD box protein 3, X-chromosomal,HLP2,D...

Human Baculovirus Insect Cells
DDX3X Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 77 kDa and the accession number is O00571.
TMPH-01901 DDX53 Protein, Human, Recombinant (His & Myc)

DEAD box protein CAGE,DEAD box protein 53,CAGE,CT26,Probable...

Human E. coli
N/A. DDX53 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 76.2 kDa and the accession number is Q86TM3.
TMPH-00971 RECQL Protein, Human, Recombinant (His)

DNA 3'-5' helicase Q1,ATP-dependent DNA helicase Q1...

Human Baculovirus Insect Cells
RECQL Protein, Human, Recombinant (His) is expressed in Baculovirus.
TMPH-00972 RECQL Protein, Human, Recombinant

RECQL,DNA helicase, RecQ-like type 1,DNA 3'-5' helicase Q1,<...

Human E. coli
RECQL Protein, Human, Recombinant is expressed in E. coli.
TMPH-00977 DDX3X Protein, Human, Recombinant (B2M & His)

DEAD box protein 3, X-chromosomal,CAP-Rf,DDX3,DDX3X,HLP2,DBX...

Human E. coli
DDX3X Protein, Human, Recombinant (B2M & His) is expressed in E. coli.
TMPH-01711 ABCC1 Protein, Human, Recombinant (His)

MRP,ATP-binding cassette sub-family C member 1,Leuk...

Human E. coli
ABCC1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 35.9 kDa and the accession number is P33527.
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重组蛋白

ATP citrate lyase/ACLY Protein, Human, Recombinant (His)
Cat.No: TMPY-02483
Species: Human
Expression System: Baculovirus Insect Cells
ATP-dependent DNA helicase dda Protein, Enterobacteria phage T4, Recombinant (His)
Cat.No: TMPH-00524
Species: Enterobacteria phage T4
Expression System: E. coli
ATP-dependent Clp protease adapter protein ClpS Protein, E. coli, Recombinant (His)
Cat.No: TMPH-00581
Species: E. coli
Expression System: E. coli
ATP5B Protein, Mouse, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-02530
Species: Mouse
Expression System: E. coli
ATP5PB Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-00964
Species: Human
Expression System: E. coli
ATP5F1B Protein, Human, Recombinant (His)
Cat.No: TMPH-00966
Species: Human
Expression System: P. pastoris (Yeast)
ATP5O Protein, Human, Recombinant (GST)
Cat.No: TMPH-00969
Species: Human
Expression System: E. coli
ATP5F1B Protein, Human, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-00967
Species: Human
Expression System: E. coli
ATP5F1A Protein, Human, Recombinant (His)
Cat.No: TMPH-00965
Species: Human
Expression System: E. coli
ATP5F1B Protein, Rat, Recombinant (His & Myc)
Cat.No: TMPH-03249
Species: Rat
Expression System: E. coli
ATP5D Protein, Human, Recombinant (His)
Cat.No: TMPY-03609
Species: Human
Expression System: E. coli
ATP5C1 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-00968
Species: Human
Expression System: E. coli
ATPase subunit g Protein, Bovine, Recombinant (His & Myc)
Cat.No: TMPH-00226
Species: Bovine
Expression System: E. coli
SLC25A6 Protein, Human, Recombinant (His & KSI)
Cat.No: TMPH-00906
Species: Human
Expression System: E. coli
RecG Protein, E. coli O157:H7, Recombinant (His & SUMO)
Cat.No: TMPH-00665
Species: E. coli
Expression System: E. coli
NADK Protein, Human, Recombinant (His)
Cat.No: TMPJ-00462
Species: Human
Expression System: E. coli
PFKP Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-05160
Species: Human
Expression System: Baculovirus Insect Cells
Human Papilloma Virus type 11 (HPV 11) Regulatory Protein E1 (His)
Cat.No: TMPH-01829
Species: HPV 11
Expression System: E. coli
Adenylate cyclase Protein, E. coli, Recombinant (His)
Cat.No: TMPH-00574
Species: E. coli
Expression System: E. coli
CD39 Protein, Rat, Recombinant (His)
Cat.No: TMPH-03283
Species: Rat
Expression System: Baculovirus Insect Cells
CD39 Protein, Rat, Recombinant (E. coli, His)
Cat.No: TMPH-03284
Species: Rat
Expression System: E. coli
Adenylate kinase Protein, Shigella flexneri, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-03503
Species: Shigella flexneri
Expression System: E. coli
Polyphosphate kinase Protein, E. coli, Recombinant (His & Myc)
Cat.No: TMPH-00713
Species: E. coli
Expression System: E. coli
Rho Protein, E. coli, Recombinant (His)
Cat.No: TMPH-00741
Species: E. coli
Expression System: E. coli
ClpP Protein, Clostridium botulinum, Recombinant (His & SUMO)
Cat.No: TMPH-00408
Species: Clostridium botulinum
Expression System: E. coli
Adenylate kinase 7 Protein, Human, Recombinant (His)
Cat.No: TMPH-00904
Species: Human
Expression System: Baculovirus Insect Cells
Endopeptidase Clp Protein, E. coli, Recombinant (His & Myc)
Cat.No: TMPH-00582
Species: E. coli
Expression System: E. coli
ABCB1 Protein, Human, Recombinant (His)
Cat.No: TMPH-00981
Species: Human
Expression System: E. coli
DHX33 Protein, Human, Recombinant (His)
Cat.No: TMPH-00980
Species: Human
Expression System: E. coli
DDX60 Protein, Human, Recombinant (His)
Cat.No: TMPH-01902
Species: Human
Expression System: E. coli
PFKM Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04479
Species: Human
Expression System: Baculovirus Insect Cells
BtuD Protein, Halobacterium salinarum, Recombinant
Cat.No: TMPH-00787
Species: Halobacterium salinarum
Expression System: E. coli
BtuD Protein, Halobacterium salinarum, Recombinant (His)
Cat.No: TMPH-00786
Species: Halobacterium salinarum
Expression System: E. coli
Rep Protein, E. coli, Recombinant (GST)
Cat.No: TMPH-00583
Species: E. coli
Expression System: E. coli
PPK2 Protein, Chlorobium tepidum, Recombinant (His & Myc)
Cat.No: TMPH-00398
Species: Chlorobaculum tepidum
Expression System: E. coli
DDX3Y Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-00979
Species: Human
Expression System: Baculovirus Insect Cells
ABCD1 Protein, Human, Recombinant (His)
Cat.No: TMPH-00970
Species: Human
Expression System: E. coli
CLPP2 Protein, Borrelia burgdorferi, Recombinant (His & Myc)
Cat.No: TMPH-00209
Species: Borrelia burgdorferi
Expression System: E. coli
ABCB5 Protein, Human, Recombinant (Trx)
Cat.No: TMPJ-01145
Species: Human
Expression System: E. coli
DDX19A Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-00976
Species: Human
Expression System: E. coli
DDX1 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-00975
Species: Human
Expression System: E. coli
DDX5 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01900
Species: Human
Expression System: E. coli
G3BP1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01998
Species: Human
Expression System: E. coli
DDX39B Protein, Human, Recombinant (GST)
Cat.No: TMPH-02133
Species: Human
Expression System: E. coli
DDX3X Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-00978
Species: Human
Expression System: Baculovirus Insect Cells
DDX53 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01901
Species: Human
Expression System: E. coli
RECQL Protein, Human, Recombinant (His)
Cat.No: TMPH-00971
Species: Human
Expression System: Baculovirus Insect Cells
RECQL Protein, Human, Recombinant
Cat.No: TMPH-00972
Species: Human
Expression System: E. coli
DDX3X Protein, Human, Recombinant (B2M & His)
Cat.No: TMPH-00977
Species: Human
Expression System: E. coli
ABCC1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01711
Species: Human
Expression System: E. coli
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Cat. No. Product Name Target Signaling Pathways
T10766 Ceritinib D7

LDK378 D7

Others Others
Ceritinib D7 (LDK378 D7) is a deuterium-labeled Ceritinib. Ceritinib is an ATP-competitive inhibitor of ALK tyrosine kinase.
TMIJ-0115 Crizotinib-d5

Crizotinib-d5 是 Crizotinib 的氘代化合物。Crizotinib 的 CAS 号为 877399-52-5。Crizotinib 是 c-MET 和 ALK 受体的 ATP 竞争性小分子酪氨酸激酶抑制剂,IC50为 8和20 nM。在细胞的实验中,它抑制 NPM-ALK 的酪氨酸磷酸化和 c-Met 的酪氨酸磷酸化。它也是ROS1抑制剂。它有肿瘤生长抑制作用。
TMID-0065 Adenine-2-d1

Adenine-2-d1 是 Adenine 的氘代化合物。Adenine 的 CAS 号为 73-24-5。Adenine 是一种嘌呤衍生物,是一种核碱基。它在细胞呼吸、以富含能量的 ATP 和 NAD 和 FAD 的形式和蛋白质合成作用,作为 DNA 和 RNA 的化学成分。
TMID-0233 Salbutamol-d9

Salbutamol-d9 是 Salbutamol 的氘代化合物。Salbutamol 的 CAS 号为 18559-94-9。Salbutamol 是短效的 β2 肾上腺素受体激动剂,用于哮喘和慢性阻塞性肺疾病 (COPD) 引发的支气管痉挛的研究。
TMIH-0512 Salbutamol-d3

Salbutamol-d3 是 Salbutamol 的氘代化合物。Salbutamol 的 CAS 号为 18559-94-9。Salbutamol 是短效的 β2 肾上腺素受体激动剂,用于哮喘和慢性阻塞性肺疾病 (COPD) 引发的支气管痉挛的研究。
TMID-0010 Mavacamten-d6

Mavacamten-d6 是 Mavacamten 的氘代化合物。Mavacamten 的 CAS 号为 1642288-47-8。MYK-461 是一种可口服的心肌肌球蛋白 ATP 酶抑制剂,在牛心脏和人心脏中的IC50值分别为 490和711 nM。
TMIH-0253 Gliclazide-d7

Gliclazide-d7 是 Gliclazide 的氘代化合物。Gliclazide 的 CAS 号为 21187-98-4。Gliclazide 是一种有效的全细胞的 β 细胞 ATP 敏感型钾流阻断剂,IC50为 184 nM,用作降糖药。
T71981 Gliclazide-d4

Gliclazide-d4 is intended for use as an internal standard for the quantification of gliclazide by GC- or LC-MS. Gliclazide is a sulfonylurea and an inhibitor of pancreatic β-cell ATP-sensitive potassium (KATP) channels. It is selective for pancreatic β-cell over cardiac and arterial smooth muscle cell KATP channels. Gliclazide (5 μM) increases insulin-induced glucose uptake and glucose transporter 4 (GLUT4) translocation to the plasma membrane in a differentiated 3T3L1 adipocyte model of insulin...
T71402 Nicorandil-d4

Nicorandil-d4 is intended for use as an internal standard for the quantification of nicorandil by GC- or LC-MS. Nicorandil is an activator of sulfonylurea receptor 2B (SUR2B) linked to ATP-sensitive potassium channel Kir6.2 (EC50 = ~10 µM) and a nitric oxide (NO) donor. It is selective for SUR2B/Kir6.2 over the SUR2A/Kir6.2 channel (EC50 = >500 µM). Nicorandil activates soluble guanylate cyclase in a cell-free assay and relaxes partially depolarized isolated bovine coronary artery strips (EC50 =...
TMID-0073 Alectinib-d8

Alectinib-d8 是 Alectinib 的氘代化合物。Alectinib 的 CAS 号为 1256580-46-7。Alectinib 是一种有效的、选择性的、口服具有活力的、ATP 竞争性的ALK抑制剂,其IC50=1.9 nM,Kd=2.4 nM,并且还抑制ALK F1174L和ALK R1275Q,其IC50分别为 1 nM 和 3.5 nM。它还有中枢神经系统渗透能力。
TMID-0127 MINOXIDIL-d10

MINOXIDIL-d10 是 MINOXIDIL 的氘代化合物。MINOXIDIL 的 CAS 号为 38304-91-5。Minoxidil 是一种是 ATP 敏感的钾通道 (KATP) 开放剂,可作为有效的口服降压药和外周血管舒张药,促进血管扩张并促进头发的生长。Minoxidil 还是一种大豆脂氧合酶的有效抑制剂,IC50为 20 μM。
TMID-0267 Glipizide-d11

Glipizide-d11 是 Glipizide 的氘代化合物。Glipizide 的 CAS 号为 29094-61-9。Glipizide 是一种有效的、具有口服活性的磺酰脲类抗糖尿病试剂 (anti-diabetic agent),在 2 型糖尿病的研究中具有价值,但不适用于1 型糖尿病。Glipizide 是通过部分阻断郎格汉斯胰岛细胞中 ATP 敏感钾通道 (KATP)发挥活性 。
TMIJ-0330 Gilteritinib-d8

Gilteritinib-d8 是 Gilteritinib 的氘代化合物。Gilteritinib 的 CAS 号为 1254053-43-4。Gilteritinib 是一种 FLT3 抑制剂 (IC50:0.29 nM),也是一种 AXL 抑制剂 (IC50:0.73 nM),具有ATP 竞争性。
TMIH-0109 Bempedoic acid-d4

Bempedoic acid-d4 是 Bempedoic acid 的氘代化合物。Bempedoic acid 的 CAS 号为 738606-46-7。ETC-1002 是一种 ATP-柠檬酸裂解酶抑制剂,可激活AMPK。它是脂质和碳水化合物代谢的调节剂。
TMIH-0065 Acalabrutinib-d4

Acalabrutinib-d4 是 Acalabrutinib 的氘代化合物。Acalabrutinib 的 CAS 号为 1420477-60-6。Acalabrutinib 是一种不可逆的、高效的、具有口服活性、选择性的第二代BTK抑制剂。它与 BTK 的 ATP 结合口袋中的 Cys481 共价结合。它在慢性淋巴细胞性白血病 (CLL) 小鼠模型中显示出强大的靶向作用和功效。

同位素标记化合物

Ceritinib D7
Cat.No: T10766
Synonym: LDK378 D7
Target: Others
Crizotinib-d5
Cat.No: TMIJ-0115
Synonym:
Target:
Adenine-2-d1
Cat.No: TMID-0065
Synonym:
Target:
Salbutamol-d9
Cat.No: TMID-0233
Synonym:
Target:
Salbutamol-d3
Cat.No: TMIH-0512
Synonym:
Target:
Mavacamten-d6
Cat.No: TMID-0010
Synonym:
Target:
Gliclazide-d7
Cat.No: TMIH-0253
Synonym:
Target:
Gliclazide-d4
Cat.No: T71981
Synonym:
Target:
Nicorandil-d4
Cat.No: T71402
Synonym:
Target:
Alectinib-d8
Cat.No: TMID-0073
Synonym:
Target:
MINOXIDIL-d10
Cat.No: TMID-0127
Synonym:
Target:
Glipizide-d11
Cat.No: TMID-0267
Synonym:
Target:
Gilteritinib-d8
Cat.No: TMIJ-0330
Synonym:
Target:
Bempedoic acid-d4
Cat.No: TMIH-0109
Synonym:
Target:
Acalabrutinib-d4
Cat.No: TMIH-0065
Synonym:
Target:
TargetMol Loading
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