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Targets Recommended: Wnt/beta-catenin

936

抑制剂 & 化合物

350

天然产物

4

化合物库

234

重组蛋白

34

同位素标记化合物

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Cat. No. Product Name
L5510 肝脏毒性化合物库

1001 compounds
1001 个肝脏毒性化合物的特有集合,可用于高通量、高内涵筛选,是毒理学研究的良好工具;
L2910 抗氧化化合物库

1314 compounds
氧化应激(Oxidative Stress,OS)是指体内氧化与抗氧化作用失衡的一种状态。氧化应激导致活性氧(ROS)大量积累,氧化程度超出抗氧化物的清除能力,从而引起氧化损伤,氧化应激损伤是许多疾病发生的基础,不同程度的氧化应激造成的细胞效应与心脑血管疾病、神经退行性病变、炎症和肿瘤密切相关。抗氧化剂是一类能够对抗氧化应激,降低氧化损伤的一类化合物。 TargetMol 抗氧化化合物库是1314 种对氧化应激具有抑制作用的小分子特有集合,是研究氧化应激的有用工具,可以用于高通量筛选和高内涵筛选。
L2550 谷氨酰胺代谢化合物库

565 compounds
565 种谷氨酰胺代谢相关的分子,可以用于高通量和高内涵筛选;
L2540 肠道微生物代谢化合物库

614 compounds
614 种肠道微生物代谢物的集合,可以用于高通量和高内涵筛选;

化合物库

肝脏毒性化合物库
Cat.No: L5510
Compounds: 1001
抗氧化化合物库
Cat.No: L2910
Compounds: 1314
谷氨酰胺代谢化合物库
Cat.No: L2550
Compounds: 565
肠道微生物代谢化合物库
Cat.No: L2540
Compounds: 614
Cat. No. Product Name Target Signaling Pathways
T4245 IWP-4

Inhibitor of Wnt Production-4

Wnt/beta-catenin Cytoskeletal Signaling; Stem Cells
IWP-4 (Inhibitor of Wnt Production-4) 是一种小分子 Wnt 抑制剂(IC50:25 nM)。
T11362 gamma-Secretase Modulators

γ-Secretase Modulators,Amyloid-β production inhibitor

Others Others
gamma-Secretase Modulators serves as a useful treatment for Alzheimer's disease by inhibiting the production of Amyloid-β. Specifically, it acts as a gamma-Secretase Modulators with an IC50 value.
T79981 Nitric oxide production-IN-1

NO Synthase Immunology/Inflammation
Nitric oxide production-IN-1(Compound 1)是从Tupistra chinensis中提取的一种NO产生抑制剂,能够抑制脂多糖诱导的大鼠腹腔巨噬细胞NO产量。
T21865 BC 11-38

PDE Metabolism
BC 11-38是一种有效的PDE11生物活性抑制剂,可提高PKA 介导的 ATF-1 磷酸化、 H295R 细胞 cAMP 水平和皮质醇生成。
T8533 ML318

Others; Antibiotic Microbiology/Virology; Others
ML318 是 PvdQ 酰基转移酶的联芳基腈抑制剂,可以结合在酰基结合位点上,IC50为 20 nM。它抑制铜绿假单胞菌的 IC50为 19 μM。它可防止嘧啶的产生并限制了铜绿假单胞菌在铁限制条件下的生长。
T0160 Anagrelide

Anagrelida,Xagrid,Anagrelidum,阿那格雷

PDE Metabolism
Anagrelide (Xagrid) 是III 型磷酸二酯酶(PDEIII)抑制剂 (IC50=36 nM),是咪唑喹唑啉衍生物。它能够抑制血小板生成,以及抗血栓形成作用,可用作血小板聚集抑制剂。
T8869 B355252

Others Others
B355252 是苯氧基噻吩磺酰胺小分子,NGF 受体激动剂。它能增强 NGF 诱导的神经突生长。它可减轻 DNA 损伤、抑制 ROS 生成、降低 LDH 水平以及预防神经元凋亡,保护缺血性神经元免受神经元损失。它具有抗细胞凋亡作用。
T14369 AZD-0284

ROR Metabolism
AZD-0284 是核受体 (RORγ) 的选择性反向激动剂。它对呼吸道疾病及斑块型寻常型银屑病具有潜在的应用价值。
T7779 Nelfinavir

AG1341,甲磺酸萘非那韦

HIV Protease Microbiology/Virology; Proteases/Proteasome
Nelfinavir (AG1341) 是一种口服活性的 HIV-1 蛋白酶抑制剂,用于抑制 HIV 感染,是一种广谱抗癌剂。
T23861 CAY10526

CAY-10526,BTH,CAY 10526

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
CAY10526 (BTH) 是 mPGES-1 的选择性抑制剂,可抑制 NF-κB 信号通路。
T6001 Nelfinavir Mesylate

Viracept,Nelfin,AG1343,AG 1343 Mesylate,甲磺酸奈非那韦

HIV Protease Microbiology/Virology; Proteases/Proteasome
Nelfinavir Mesylate (Viracept) 是一种口服活性的 HIV-1蛋白酶抑制剂,用于抑制 HIV 感染,是一种广谱抗癌剂。
T36584 HNMPA-(AM)3

Tyrosine Kinases Tyrosine Kinase/Adaptors
HNMPA-(AM)3 抑制 ERK 磷酸化的激活以及促促胸腺激素 (PTTH) 刺激蜕皮类固醇产生。 此外,HNMPA-(AM)3 对蜕皮类固醇产生 (IC50=14.2 μM) 和胰岛素受体活性 (IC50=14.2 μM 和 200 μM,在蚊子和哺乳动物中分别) 具有抑制作用。
T10866 Cot inhibitor-2

TNF; MAPK Apoptosis; MAPK
Cot inhibitor-2 是一种 cot (Tpl2/MAP3K8) 抑制剂(IC50 : 1.6 nM),具有有效性,选择性和口服活性。Cot inhibitor-2 对LPS 刺激的人全血中 TNF-α 的产生具有抑制作用,IC50 为 0.3 μM。
T2386 Pirfenidone

S-7701,AMR-69,S-7701,AMR69,吡非尼酮

CCR; TGF-beta/Smad Immunology/Inflammation; Microbiology/Virology; Stem Cells
Pirfenidone (AMR69) 是一种抗纤维化剂,可减弱纤维细胞中CCL2和CCL12的产生。它可抑制细胞生长,并能降低人胶质瘤细胞系中的TGF-β2蛋白水平,具有抗炎活性。
T1846 Y-320

Y320

IL Receptor; Lipase; Interleukin Immunology/Inflammation; Metabolism
Y-320 是一种免疫调节剂,能阻碍IL-15刺激CD4 T 细胞后的IL-17的产生,IC50=20~60 nM。
T72322 R 59-022 hydrochloride

DKGI-I hydrochloride,Diacylglycerol kinase inhibitor I hydrochloride,DKGI-I hydrochloride ; Diacylglycerol kinase inhibitor I hydrochloride

5-HT Receptor; PKC Chromatin/Epigenetic; Cytoskeletal Signaling; GPCR/G Protein; Neuroscience
R 59-022 hydrochloride (DKGI-I hydrochloride) 是一种 5-HT Receptor 拮抗剂,可激活蛋白激酶 C (PKC)。R 59-022 hydrochloride 是一种 DGK 抑制剂 (IC50:2.8 µM),可抑制 OAG 磷酸化为 OAPA。R 59-022 增强血小板中凝血酶诱导的甘油二酯的产生,并抑制嗜中性粒细胞中磷脂酸的产生。
T0576 Diethylaminoethoxyethanol

Others Others
Diethylaminoethoxyethanol 用于生产止咳药Toclase 等。
T3571 SU5201

NSC 247030

Others; Interleukin Immunology/Inflammation; Others
NSC 247030 对白细胞介素 2 (IL-2) 的产生具有抑制作用。
T29797 AKB-6899

AKB6899

VEGFR; HIF/HIF Prolyl-Hydroxylase; HIF Angiogenesis; Chromatin/Epigenetic; Metabolism; Tyrosine Kinase/Adaptors
AKB-6899 是脯氨酰羟化酶结构域 3 (PHD3) 的抑制剂,可增加 GM-CSF 处理的巨噬细胞产生的 VEGF 受体的可溶形式 (sVEGFR-1)。 AKB-6899 能稳定 HIF-2α,从而诱导肿瘤相关巨噬细胞产生 sVEGFR-1 并减少肿瘤生长。
T0644 3-Amino-5-methylisoxazole

Others Others
3-Amino-5-methylisoxazole 是医药中间体,用于生产磺胺类药物。
T14219 Aminaftone

Aminaphthone

Endothelin Receptor GPCR/G Protein
Aminaftone 是 4-氨基苯甲酸的衍生物,可抑制内皮素-1 (ET-1) 的产生,可用于研究高血压和系统硬化症。
T30219 AVE-9488

AVE 9488,AVE9488

NOS; NO Synthase Immunology/Inflammation
AVE-9488 是一种新型的内皮 NO 合酶(eNOS)增强剂,可上调eNOS表达,诱导 NO 的产生,可改善门静脉高压症。
T8640 G6PDi-1

Dehydrogenase Metabolism
G6PDi-1 是一种有效的 G6PD 抑制剂。它消耗 NADPH 并减少炎性细胞因子的产生。
T11897 Telotristat ethyl

LX1606

Hydroxylase Metabolism
Telotristat ethyl (LX1606) 是一种口服具有活力的色氨酸羟化酶抑制剂,可抑制血清素的产生。
T67907 Nimucitinib

JAK Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
Nimucitinib 是一种 Janus 激酶 (JAK) 抑制剂,可用来治疗干眼症,促进泪液分泌。
T32658L Leteprinim

AIT082 acid,AIT 082 acid,AIT-082 acid

Others Others
Leteprinim (AIT 082 acid) 是一种次黄嘌呤衍生物,可刺激体外神经突生长和星形胶质细胞产生腺苷和神经营养因子。
T1251 Dicloralurea

双(三氯乙醛基)脲,Dichlorolurea,双 (三氯乙醛基) 脲,DCU

Others Others
Dicloralurea (DCU) 是一种兽用的食品添加剂,可用作生长刺激剂。
T21853 (E)-AG 556

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
(E)-AG 556 是有效的、选择性 EGFR 抑制剂。(E)-AG 556阻断 LPS 诱导的促炎因子 TNF-α 的产生。
T7517 Tiadinil

3'-氯-4,4'-二甲基-1,2,3-噻二唑-5-甲酰苯胺,噻酰菌胺

Others; Antibacterial Microbiology/Virology; Others
Tiadinil 是一种系统获得性抗性的植物激活剂,可促进草食动物诱导的植物挥发物的产生。
T33296 Merodantoin

Apoptosis Apoptosis
Merodantoin 是一种凋亡诱导剂,可引发与 ROS 依赖性自噬相关的细胞凋亡。 Merodantoin 靶向表达参与 Akt 依赖性 ROS 产生的 KRAS 突变的癌细胞。
T28238 ONC1-13B

ONC 113B,ONC-1-13B,ONC 1 13B,ONC-113B

Androgen Receptor Endocrinology/Hormones
ONC1-13B 是一种高效的雄激素受体(AR)拮抗剂,对雄激素敏感的人 PCa LNCaP 细胞中抑制 PSA 产生的ic50在 59-80 nM范围内。
T0491 Ethylvanillin

Ethylprotal,Bourbonal,乙基香兰素,Rhodiarome,Ethyl vanillin

Others Others
Ethylvanillin (Rhodiarome) 是一种食用香料,效果是 Vanillin 的三倍,可用于巧克力的生产。
T60004 SRI-37330

Others Others
SRI-37330 抑制胰高血糖素的分泌和功能,减少肝葡萄糖的产生,并逆转肝脂肪变性。
T36442L (Hyp³)-Bradykinin acetate

(Hyp³)-Bradykinin acetate (37642-65-2 Free base)

Bradykinin Receptor GPCR/G Protein
(Hyp³)-Bradykinin acetate 是一种缓激肽 B2 受体激动剂,可刺激培养的人成纤维细胞中磷酸肌醇的产生。
T8440 LASSBio-1135

TNF; TRP/TRPV Channel Apoptosis; Membrane transporter/Ion channel
LASSBio-1135 是一种口服有效的 TRPV1 拮抗剂和 TNF-α 生成抑制剂。
T25737 Linetastine

TMK 688,TMK-688,TMK688

Lipoxygenase; LTR; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
Linetastine (TMK-688) 是一种 5-脂氧合酶抑制剂(5-LOX),能抑制白三烯的产生,并能拮抗组胺的作用。Linetastine可用于研究哮喘、动脉粥样硬化和消化性溃疡。
T6657 SB273005

Integrin Cytoskeletal Signaling
SB273005 是一种具有口服活性和高效性非肽整合素αvβ3 拮抗剂,抑制 αvβ3 和 αvβ5,可减少怀孕小鼠中 Th2 细胞和细胞因子 IL-10 的产生。
T13180 TOK-8801

Others Others
TOK-8801 是一种合成的二氢咪唑噻唑羧酰胺,具有免疫调节活性,通过去除 T 细胞消除抗体产生的刺激作用。
T11188L Emixustat hydrochloride

ACU-4429 hydrochloride

Others Others
Emixustat hydrochloride (ACU-4429 hydrochloride) 能够高效抑制11-顺式-视黄醇的生产(IC50:232±3 nM)。
T19480 NO-prednisolone

NCX-1015

IL Receptor Immunology/Inflammation
NO-prednisolone (NCX-1015) 是一种有效刺激体内IL-10产生的化合物,是一种释放一氧化氮(NO)的Prednisolone 衍生物。
T20110 Ethylene thiourea

ETU,Imidazolidinethione,NCI C03372,NCIC03372,NCI-C03372,亚乙基硫脲

Others Others
Ethylene thiourea (NCIC03372) 是一种用于水果和蔬菜生产的农药。它还用作基于质子化学交换依赖性饱和转移的 MRI 研究的新型造影剂。
T22600 BC 11 hydrobromide

Apoptosis; Serine Protease; ROS Apoptosis; Immunology/Inflammation; Proteases/Proteasome
BC 11 hydrobromide是一种选择性 TMPRSS2 和尿激酶 (uPA) 抑制剂 。BC-11 诱导线粒体活性减弱,促进活性氧的产生,促进细胞凋亡,可用于研究乳腺癌。
T4508 Glycyl-L-Histidyl-L-Lysine

Others Others
Glycyl-L-Histidyl-L-Lysine 是一种肝细胞生长因子和一种合成的肝营养剂,可刺激肝红细胞生成因子的产生。
T77574 ROS inducer 1

ROS; Antibiotic Immunology/Inflammation; Microbiology/Virology
ROS inducer 1 是一种具有杀菌作用的小分子化合物,对 Xanthomonas axonopodis pv. citri (Xac)、Xanthomonas oryzae pv. oryzae (Xoo)和 Pseudomonas syringae pv. actinidiae (Psa) 具有抑制作用。ROS inducer 1 诱 Xanthomonas 细胞内 ROS 的产生可用于研究农作物细菌感染。
T27850 LP-471756

LP471756

GPR Endocrinology/Hormones; GPCR/G Protein
LP-471756 是 GPR139 的特异性拮抗剂,可抑制 LP-360924 刺激的 cAMP 产生 (IC50 = 640 nM)。
T3572 NSC 15364

1,3-Bis(4-aminophenyl)urea,NSC15364

Apoptosis; Others; VDAC Apoptosis; Membrane transporter/Ion channel; Others
NSC 15364 (1,3-Bis(4-aminophenyl)urea) 是一种 VDAC1寡聚化和细胞凋亡抑制剂。
T38423 CL097

CL097

Reactive Oxygen Species; TLR Immunology/Inflammation; Metabolism; NF-κB
CL097 是 TLR7 和 TLR8 的有效激动剂。 CL097 诱导巨噬细胞中的促炎细胞因子和 NADPH 氧化酶引发,从而增加 fMLF 刺激的 ROS 产生。
T20882 4-Nitrobenzoic acid

Kyselina p-nitrobenzoova,4Nitrobenzoic acid,Nitrodracylic acid,4 Nitrobenzoic acid

4-Nitrobenzoic acid (4Nitrobenzoic acid) 是一种药物中间体,常在叶酸、DABA、PABA 和染料的生产中出现。
T5641 RP-54745

Interleukin Immunology/Inflammation
RP-54745 是一种能抑制噬细胞刺激和的白介素-1 的产生的化合物,对风湿病的治疗具有潜在的研究价值。
T24984 5J-4

Calcium Channel Membrane transporter/Ion channel; Metabolism
5J-4 是一种有效的钙释放激活钙通道 (CRAC) 和钙池操纵性钙内流(SOCE) 阻滞剂。 5J-4 减少 IL-17 的产生并降低 RORα 和 RORγt 的表达。

化合物

IWP-4
Cat.No: T4245
Synonym: Inhibitor of Wnt Production-4
Target: Wnt/beta-catenin
gamma-Secretase Modulators
Cat.No: T11362
Synonym: γ-Secretase Modulators,Amyloid-β production inhibitor
Target: Others
Nitric oxide production-IN-1
Cat.No: T79981
Synonym:
Target: NO Synthase
BC 11-38
Cat.No: T21865
Synonym:
Target: PDE
ML318
Cat.No: T8533
Synonym:
Target: Others, Antibiotic
Anagrelide
Cat.No: T0160
Synonym: Anagrelida,Xagrid,Anagrelidum,阿那格雷
Target: PDE
B355252
Cat.No: T8869
Synonym:
Target: Others
AZD-0284
Cat.No: T14369
Synonym:
Target: ROR
Nelfinavir
Cat.No: T7779
Synonym: AG1341,甲磺酸萘非那韦
Target: HIV Protease
CAY10526
Cat.No: T23861
Synonym: CAY-10526,BTH,CAY 10526
Target: Prostaglandin Receptor
Nelfinavir Mesylate
Cat.No: T6001
Synonym: Viracept,Nelfin,AG1343,AG 1343 Mesylate,甲磺酸奈非那韦
Target: HIV Protease
HNMPA-(AM)3
Cat.No: T36584
Synonym:
Target: Tyrosine Kinases
Cot inhibitor-2
Cat.No: T10866
Synonym:
Target: TNF, MAPK
Pirfenidone
Cat.No: T2386
Synonym: S-7701,AMR-69,S-7701,AMR69,吡非尼酮
Target: CCR, TGF-beta/Smad
Y-320
Cat.No: T1846
Synonym: Y320
Target: IL Receptor, Lipase, Interleukin
R 59-022 hydrochloride
Cat.No: T72322
Synonym: DKGI-I hydrochloride,Diacylglycerol kinase inhibitor I hydrochloride,DKGI-I hydrochloride ; Diacylglycerol kinase inhibitor I hydrochloride
Target: 5-HT Receptor, PKC
Diethylaminoethoxyethanol
Cat.No: T0576
Synonym:
Target: Others
SU5201
Cat.No: T3571
Synonym: NSC 247030
Target: Others, Interleukin
AKB-6899
Cat.No: T29797
Synonym: AKB6899
Target: VEGFR, HIF/HIF Prolyl-Hydroxylase, HIF
3-Amino-5-methylisoxazole
Cat.No: T0644
Synonym:
Target: Others
Aminaftone
Cat.No: T14219
Synonym: Aminaphthone
Target: Endothelin Receptor
AVE-9488
Cat.No: T30219
Synonym: AVE 9488,AVE9488
Target: NOS, NO Synthase
G6PDi-1
Cat.No: T8640
Synonym:
Target: Dehydrogenase
Telotristat ethyl
Cat.No: T11897
Synonym: LX1606
Target: Hydroxylase
Nimucitinib
Cat.No: T67907
Synonym:
Target: JAK
Leteprinim
Cat.No: T32658L
Synonym: AIT082 acid,AIT 082 acid,AIT-082 acid
Target: Others
Dicloralurea
Cat.No: T1251
Synonym: 双(三氯乙醛基)脲,Dichlorolurea,双 (三氯乙醛基) 脲,DCU
Target: Others
(E)-AG 556
Cat.No: T21853
Synonym:
Target: EGFR
Tiadinil
Cat.No: T7517
Synonym: 3'-氯-4,4'-二甲基-1,2,3-噻二唑-5-甲酰苯胺,噻酰菌胺
Target: Others, Antibacterial
Merodantoin
Cat.No: T33296
Synonym:
Target: Apoptosis
ONC1-13B
Cat.No: T28238
Synonym: ONC 113B,ONC-1-13B,ONC 1 13B,ONC-113B
Target: Androgen Receptor
Ethylvanillin
Cat.No: T0491
Synonym: Ethylprotal,Bourbonal,乙基香兰素,Rhodiarome,Ethyl vanillin
Target: Others
SRI-37330
Cat.No: T60004
Synonym:
Target: Others
(Hyp³)-Bradykinin acetate
Cat.No: T36442L
Synonym: (Hyp³)-Bradykinin acetate (37642-65-2 Free base)
Target: Bradykinin Receptor
LASSBio-1135
Cat.No: T8440
Synonym:
Target: TNF, TRP/TRPV Channel
Linetastine
Cat.No: T25737
Synonym: TMK 688,TMK-688,TMK688
Target: Lipoxygenase, LTR, Histamine Receptor
SB273005
Cat.No: T6657
Synonym:
Target: Integrin
TOK-8801
Cat.No: T13180
Synonym:
Target: Others
Emixustat hydrochloride
Cat.No: T11188L
Synonym: ACU-4429 hydrochloride
Target: Others
NO-prednisolone
Cat.No: T19480
Synonym: NCX-1015
Target: IL Receptor
Ethylene thiourea
Cat.No: T20110
Synonym: ETU,Imidazolidinethione,NCI C03372,NCIC03372,NCI-C03372,亚乙基硫脲
Target: Others
BC 11 hydrobromide
Cat.No: T22600
Synonym:
Target: Apoptosis, Serine Protease, ROS
Glycyl-L-Histidyl-L-Lysine
Cat.No: T4508
Synonym:
Target: Others
ROS inducer 1
Cat.No: T77574
Synonym:
Target: ROS, Antibiotic
LP-471756
Cat.No: T27850
Synonym: LP471756
Target: GPR
NSC 15364
Cat.No: T3572
Synonym: 1,3-Bis(4-aminophenyl)urea,NSC15364
Target: Apoptosis, Others, VDAC
CL097
Cat.No: T38423
Synonym: CL097
Target: Reactive Oxygen Species, TLR
4-Nitrobenzoic acid
Cat.No: T20882
Synonym: Kyselina p-nitrobenzoova,4Nitrobenzoic acid,Nitrodracylic acid,4 Nitrobenzoic acid
Target:
RP-54745
Cat.No: T5641
Synonym:
Target: Interleukin
5J-4
Cat.No: T24984
Synonym:
Target: Calcium Channel
Cat. No. Product Name Target Signaling Pathways
TN1546 Dactylorhin A

NO Synthase Immunology/Inflammation
Dactylorhin A 是一种琥珀酸衍生物酯,分离自 Gymnadenia conopsea 根茎中。它对 RAW 264.7 巨噬细胞产生 NO 有中等程度的抑制作用。
TN2167 Rutaevin

Reactive Oxygen Species; NO Synthase Immunology/Inflammation; Metabolism; NF-κB
Rutaevin 从Euodia rutaecarpa 中分离。它对 Raw 264.7 巨噬细胞中 LPS 诱导的NO 产生具有抑制作用。
T5826 Eupalinolide A

HSP Cytoskeletal Signaling; Metabolism
Eupalinolide A 是分离于林泽兰中的一种天然产物,通过抑制 HSF1 与 HSP90 的相互作用,激活 HSF1,诱导 HSP70 的表达。它对 A-549、BGC-823、SMMC-7721 和 HL-60 肿瘤细胞系具有强大的细胞毒性。
T15686 L-741626

3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole

Dopamine Receptor GPCR/G Protein; Neuroscience
L-741626 (3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole) 是D2多巴胺受体选择性拮抗剂,对人 D2、D3 和 D4 受体的Ki 分别为 2.4、100 和 220 nM。
T4834 Indole-3-acetamide

3-Indoleacetamide,3-Indolylacetamide,3-吲哚乙酰胺

Others; Endogenous Metabolite Metabolism; Others
Indole-3-acetamide 是一种 indole-3-acetic acid 的生物合成中间体。其中 Indole-3-acetic acid 是植物生长素类中最常见的天然植物生长激素。
T1633 β-Carotene

beta-胡萝卜素,Carotaben,Beta-Carotene,Provitamin A,β-胡萝卜素

Apoptosis; ROS; Endogenous Metabolite Apoptosis; Immunology/Inflammation; Metabolism
β-Carotene (Provitamin A) 是一种天然存在的视黄醇(维生素 A)前体。它是一种 ROS 调节剂,具有抗氧化和抗炎活性。它可作为抗氧化剂或者促氧化剂,可诱导乳腺癌细胞凋亡,具有抗癌活性。
TN1109 3-O-Acetyl-16α-hydroxydehydrotrametenolic acid

3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid,3-O-乙酰基-16Α-羟基松苓新酸

NOS; NO Synthase; Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
3-O-Acetyl-16α-hydroxydehydrotrametenolic acid (3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid) 是三萜类化合物。它能够作用于 LPS 刺激的 Raw264.7 细胞,减少NO 产生和 iNOS 表达,具有消炎作用。
TN3176 6-Methoxynaringenin

NO Synthase Immunology/Inflammation
6-Methoxynaringenin 是 Scutellaria barbata D. Don 的地上部分,可有效抑制 NO 的产生,IC50 值为 25.8 μM。
TN7229 Baihuaqianhuoside

Praeroside

Others Others
Baihuaqianhuoside (Praeroside) 是一种香豆素苷。Baihuaqianhuoside 可以从西番莲和 Hindenia solanacea 的根部分离出来,是首次从 P. japonicum 身上分离出来的。Baihuaqianhuoside 在体外具有抗炎活性,可以用于炎症的研究。Baihuaqianhuoside 对1,1-二苯基-2-丙烯酰肼自由基的清除作用,以及对2,2'-偶氮双(2-脒基丙烷)二盐酸盐诱导的脂质体氧化的抑制作用。
TN1021 Secologanic acid

NO Synthase Immunology/Inflammation
Secologanic acid 是裂环烯醚萜苷的一种。
T5S1981 alpha-Cyperone

(+)-α-Cyperone,α-香附酮,α-Cyperone

Others; Endogenous Metabolite Metabolism; Others
alpha-Cyperone (α-Cyperone) 与 IL-6, Cox-2, Cdc42, Nck-2, Rac1 的表达下调相关,从而能够抑制炎症反应。
T22312 Dodecanedioic acid

Endogenous Metabolite Metabolism
Dodecanedioic acid 是一种二羧酸,可用于合成工程塑料尼龙612。Dodecanedioic acid 是工业生产的基础油料。
T13522 7-Ketolithocholic acid

3α-Hydroxy-7-oxo-5β-cholanic acid

Endogenous Metabolite Metabolism
7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid) (3α-Hydroxy-7-oxo-5β-cholanic acid) is capable of absorption and serves to suppress the production of endogenous bile acid and the secretion of biliary cholesterol.
TQ0070 Luteolin-3-O-beta-D-glucuronide

Others Others
Luteolin-3-O-beta-D-glucuronide 是木犀草素葡萄糖醛酸,木犀草素的 3’ 端位置有 β-d-葡萄糖苷酸残基。
T0129 Sanguinarine chloride

Pseudochelerythrine chloride,血根碱,氯化血根碱,Sanguinarium chloride

Apoptosis; EGFR; VEGFR; Antibacterial; Parasite; Autophagy Angiogenesis; Apoptosis; Autophagy; JAK/STAT signaling; Microbiology/Virology; Tyrosine Kinase/Adaptors
Sanguinarine chloride (Pseudochelerythrine chloride) 是一种来源于 Sanguinaria Canadensis 的生物碱,通过激活活性氧的产生,诱导细胞凋亡。
T8949 UDP-g acid

Others Others
UDP-g acid 是一种用于生产多糖的糖,是抗坏血酸生物合成的中间体。
T3S1089 Phillygenin

Epipinoresinol methyl ether,(+)-Phillygenin,Phillygenol,Sylvatesmin,Forsythigenol,连翘脂素

Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB
Phillygenin (Sylvatesmin) 是一种连翘的活性组分,有很多的药用价值,包括抗氧化剂,降血脂,抑制低密度脂蛋白氧化。
T3779 Crocin II

Crocin 2,西红花苷II,Crocetin gentiobiosylglucosyl ester,藏红花,Tricrocin,Crocin B

Caspase; COX; NO Synthase Apoptosis; Immunology/Inflammation; Neuroscience; Proteases/Proteasome
Crocin II (Crocetin gentiobiosylglucosyl ester) 是从栀子果实中分离出来的一种天然产物,具有抗氧化、抗癌和抗抑郁活性。它抑制 iNOS 和 COX-2的蛋白质和 m-RNA 的表达,还抑制NO 产生,IC50值为 31.1 μM。
TQ0301 Kuwanon A

NO Synthase Immunology/Inflammation
Kuwanon A 抑制一氧化氮的产生 (IC50: 10.5 μM)。Kuwanon A 是从桑树 (Morus alba L.) 中分离出来的黄酮衍生物。
T5727 CAFESTOL

咖啡醇,咖啡油醇

ERK; NF-κB; COX; PGE Synthase Immunology/Inflammation; MAPK; Neuroscience; NF-κB
Cafestol 是咖啡特有的一种二萜,可靶向 AP-1 抑制ERK,有化学预防、抗肿瘤、保肝、抗氧化和抗炎作用。它通过抑制NF-kB 活化途径强烈的抑制 PGE2的产生,还抑制 LGE 激活的 RAW264.7 细胞中的PGE2产生和环氧合酶(COX-2)的 mRNA 表达。
T2O2741 Thiamine monochloride

Thiamine chloride,Vitamin B1

Others; Antioxidant; Endogenous Metabolite; Antibacterial Metabolism; Microbiology/Virology; Others; oxidation-reduction
Thiamine monochloride (Vitamin B1) 是人体必不可少的维生素,具有促红细胞生成、调节血糖、抗氧化和调节情绪的作用。Thiamine monochloride 抑制铅引起的脂质过氧化反应,从而防止铅中毒。Thiamine monochloride 在摄入食物的细胞产生能量中起重要作用,并能增强正常的神经元活性。
T0062 Folic acid

Folate,Vitamin B9,Pteroylglutamic acid,Vitamin M,叶酸,Folacin

DNA/RNA Synthesis; Endogenous Metabolite Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
Folic acid (Vitamin B9) 是维生素B9,是合成DNA/RNA,新细胞产生和维持的必要成分。
T12588 Pyridoxylamine

pyridoxamine,吡多胺

Endogenous Metabolite Metabolism
Pyridoxylamine (pyridoxamine) 是脂质化终产物和糖基化终产物抑制剂,能够防止糖尿病引起的视网膜血管病变。
T8010 Dibutyl sebacate

Dibutyl decanedioate,癸二酸二丁酯

Others Others
Dibutyl sebacate (Dibutyl decanedioate) 是一种常作为塑料生产中的增塑剂的癸二酸二丁酯。
T30086 Anthragallol

Anthragallic acid,1,2,3-Trihydroxyanthraquinone

Others Others
Anthragallol(1,2,3-Trihydroxyanthraquinone) 通过与 DNA 结合而显示出细胞毒性。Anthragallol 可作为分析试剂,可用于生产棕色酸洗色料。
T37341 N-Acetyltyramine

Antibacterial Microbiology/Virology
N-Acetyltyramine 是一种群体感应抑制剂,由溶藻弧菌 M3-10 产生。N-Acetyltyramine 可以抑制C. violaceumATCC 12472 的群体感应。它可以逆转阿霉素耐药白血病 P388 细胞的耐药性。
T8014 Epoxylinalool

氧化芳樟醇,2-(2-Hydroxy-2-Propyl)-5-Methyl-5-Vinyltetrahydrofuran

Others Others
Epoxylinalool (2-(2-Hydroxy-2-Propyl)-5-Methyl-5-Vinyltetrahydrofuran) 是一种天然存在的单萜醇,广泛用于香水和调味品的生产。
TN6985 Anhydronotoptol

NO Synthase Immunology/Inflammation
Anhydronotoptol (4-{[(2E,5E)-3,7-dimethylocta-2,5,7-trien-1-yl]oxy}-7H-furo[3,2-g]chromen-7-one) 是一种可从伞科植物羌活中提取得到的天然化合物。Anhydronotoptol 是一种有效的 一氧化氮生成抑制剂, 抑制 LPS 诱导的 RAW 264.7 细胞 NO 生成,其 IC50 值为 36.6 μM。
T4S2014 5,15-Diacetyl-3-benzoyllathyrol

,大戟因子L3,二乙酰基苯甲酰基香豌豆醇,5,15-二乙酰基-3-苯甲酰千金子二萜醇;千金二萜醇二乙酰苯甲酰酯,Euphorbia factor L3

Others Others
5,15-Diacetyl-3-benzoyllathyrol (Euphorbia factor L3) 是一种具有抗癌作用的萜类化合物。
TN4228 Hulupinic acid

NO Synthase Immunology/Inflammation
Hulupinic acid 是主要的啤酒花酸氧化产物,可能对巨噬细胞RAW 264.7细胞NO 产生NO 有抑制作用。
T4972 2'-Deoxycytidine-5'-diphosphate trisodium

dCDP,2'-脱氧胞苷-5'-二磷酸三钠盐

Endogenous Metabolite Metabolism
2'-Deoxycytidine-5'-diphosphate trisodium (dCDP) 是内源性代谢产物的一种。
T2S0765 Epibetulinic acid

NO Synthase; Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
Epibetulinic acid 对细菌内毒素刺激的小鼠巨噬细胞 (RAW 264.7) 中 NO 和前列腺素 E(2) 的产生具有有效的抑制作用,IC50分别为 0.7 和 0.6 μM,具有抗炎活性。
T2S2150 Noricaritin

诺里卡汀,去甲淫羊藿黄素

Others Others
Noricaritin 是一种来源于淫羊藿根的黄酮类化合物,可诱导肺组织细胞增殖,抑制人肺上皮细胞中促炎细胞因子和趋化因子的产生。
T2S2173 (E)-Naringenin chalcone

Isosalipurpol,柚皮苷查尔酮,Chalconaringenin,trans-2'4'6'4-tetrahydroxychalcone,柚皮素查耳酮

Others Others
Naringenin chalcone (Isosalipurpol) 是一种黄酮醇生物合成的中间体,在查耳酮异构酶的作用下,自发代谢成柚皮素。它具有抗炎和抗过敏活性。
T3S1944 Darutoside

Darutin,豯莶苷

Others Others
Darutoside (Darutin) 是一种二萜化合物,提取自Siegesbeckia 中。
T8249 Hexahydrofarnesyl acetone

植酮,Phytone

Others; Antibacterial Microbiology/Virology; Others
Hexahydrofarnesyl acetone (Phytone) 是从Launaea mucronata 中分离得到的倍半萜,具有抗菌和抗炎活性,可研究缓解疼痛。
T38475 2,6-Dimethylpyrazine

Others Others
2,6-Dimethylpyrazine 是食品工业中不可缺少的调味添加剂,也是生产降糖和抗脂解化合物的重要底物。
T2228 Adipic acid

Others; Endogenous Metabolite Metabolism; Others
Adipic acid 是一种生产尼龙的前体。它被发现与 HMG-CoA 裂解酶缺乏症,肉毒碱激酶缺乏症,中链酰基脱氢酶缺乏症相关,这些都是天生代谢异常导致的。
TMO2681 Xanthosine

9-Beta-D-Ribofuranosylxanthine,黄嘌呤核苷,Xanthine riboside

Others; Endogenous Metabolite Metabolism; Others
Xanthosine (9-Beta-D-Ribofuranosylxanthine) 是黄嘌呤核苷,它能够提高山羊和牛的乳腺干细胞数量和产奶量。
T9115 Vanillic Acid

4-hydroxy-3-methoxybenzoic acid,Acide vanillique,香草酸,Vanillate

Others; NF-κB; Endogenous Metabolite; Antibacterial Metabolism; Microbiology/Virology; NF-κB; Others
Vanillic Acid (Acide vanillique) 是一种在食用植物和水果中发现的调味剂,可抑制NF-κB 活化,具有抗菌,抗炎等活性。
T6S0107 Peimine

贝母素甲,Wanpeinine A,Dihydroisoimperialine,Verticine,贝母甲素

Others Others
Peimine (Wanpeinine A) 是一种天然化合物,具有很好抗炎症活性。
T5774 Demethylsuberosin

7-去甲基软木花椒素,7-demethylsuberosin

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
7-Demethylsuberosin (7-demethylsuberosin) 是一种分离自 Angelica gigasNakai 中的香豆素类化合物,具有抗炎作用。
T7053 p-Hydroxycinnamic acid

p-Coumaric acid,p-Cumaric acid,p-Hydroxy-cinnamic acid,对羟基肉桂酸,NSC 59260

Thrombin; Endogenous Metabolite; Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation; Metabolism; Proteases/Proteasome
p-Hydroxycinnamic acid (NSC-59260) 是常见的食用酚,可抑制血小板活性,对血栓素 B2 和前列腺素 E2 的 IC50值分别为 371 和 126 μM。
T40388 Methyl 5-hydroxypyridine-2-carboxylate

Others Others
Methyl 5-hydroxypyridine-2-carboxylate 是存在于 Mahonia fortune 茎中的一种酚酸,在体外表现出 NO 抑制活性。
T2A2476 L-Hydroxyproline

羟脯氨酸,trans-4-Hydroxy-L-proline,L-Hydroxyprolin,Trans-4-Hydroxyproline

Endogenous Metabolite Metabolism
L-Hydroxyproline (L-Hydroxyprolin) 是羟脯氨酸的异构体之一,是药物生产中有用的手性结构单元。
TQ0218 Deoxyandrographolide

去氧穿心莲内酯,14-deoxyandrographolide

IL Receptor; TNF Apoptosis; Immunology/Inflammation
Deoxyandrographolide (14-deoxyandrographolide) 抑制 LPS 诱导的 iNOS mRNA 水平升高以及促炎症介质 TNF-α 和 IL-6 的产生。它增强 NGF 诱导的神经突起生长。
T10668 Camalexin

Reactive Oxygen Species; ROS; Antibacterial; Antifungal Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
Camalexin 是从Camelina sativa 和Arabidopsis 中分离出来的一种植物抗毒素,可诱导活性氧的产生,具有抗菌、抗真菌、抗增殖和抗癌活性。
T3756 Allitol

Allodulcit,蒜糖醇,Allodulcitol,d-allitol

Others Others
Allitol (d-allitol) 是一种罕见的可作为甜味剂天然多元醇。它是制备 azasugars 的重要中间体,可用于制备抗癌症、糖尿病及包括艾滋病在内的病毒感染的药物。
TN1373 α-Humulene

Alpha-caryophyllene,ALPHA-律草烯

TNF; NOS; COX Apoptosis; Immunology/Inflammation; Neuroscience
α-Humulene (Alpha-caryophyllene) 是 Tanacetum vulgareL. 精油的主要成分,显示出抗炎作用,IC50=15±2 μg/mL。它抑制 iNOS 和COX-2表达。
T0572 Methyl 3,4,5-trimethoxybenzoate

Methyl gallate trimethyl ether,Methyl EudesMate,3,4,5-Trimethoxybenzoic acid methyl ester,Methyl tri-O-methylgallate,甲氧苄啶杂质H,Trimethylgallic acid methyl ester

Others; Antioxidant Others; oxidation-reduction
Methyl EudesMate 是由 Gallic acid 为原料合成得到,具有抗氧化活性,常用于生产磺胺增效剂中间体、甲氧苄氨嘧啶 (TMP)以及许多其它药物。
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天然产物

Dactylorhin A
Cat.No: TN1546
Synonym:
Target: NO Synthase
Rutaevin
Cat.No: TN2167
Synonym:
Target: Reactive Oxygen Species, NO Synthase
Eupalinolide A
Cat.No: T5826
Synonym:
Target: HSP
L-741626
Cat.No: T15686
Synonym: 3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole
Target: Dopamine Receptor
Indole-3-acetamide
Cat.No: T4834
Synonym: 3-Indoleacetamide,3-Indolylacetamide,3-吲哚乙酰胺
Target: Others, Endogenous Metabolite
β-Carotene
Cat.No: T1633
Synonym: beta-胡萝卜素,Carotaben,Beta-Carotene,Provitamin A,β-胡萝卜素
Target: Apoptosis, ROS, Endogenous Metabolite
3-O-Acetyl-16α-hydroxydehydrotrametenolic acid
Cat.No: TN1109
Synonym: 3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid,3-O-乙酰基-16Α-羟基松苓新酸
Target: NOS, NO Synthase, Prostaglandin Receptor
6-Methoxynaringenin
Cat.No: TN3176
Synonym:
Target: NO Synthase
Baihuaqianhuoside
Cat.No: TN7229
Synonym: Praeroside
Target: Others
Secologanic acid
Cat.No: TN1021
Synonym:
Target: NO Synthase
alpha-Cyperone
Cat.No: T5S1981
Synonym: (+)-α-Cyperone,α-香附酮,α-Cyperone
Target: Others, Endogenous Metabolite
Dodecanedioic acid
Cat.No: T22312
Synonym:
Target: Endogenous Metabolite
7-Ketolithocholic acid
Cat.No: T13522
Synonym: 3α-Hydroxy-7-oxo-5β-cholanic acid
Target: Endogenous Metabolite
Luteolin-3-O-beta-D-glucuronide
Cat.No: TQ0070
Synonym:
Target: Others
Sanguinarine chloride
Cat.No: T0129
Synonym: Pseudochelerythrine chloride,血根碱,氯化血根碱,Sanguinarium chloride
Target: Apoptosis, EGFR, VEGFR, Antibacterial, Parasite, Autophagy
UDP-g acid
Cat.No: T8949
Synonym:
Target: Others
Phillygenin
Cat.No: T3S1089
Synonym: Epipinoresinol methyl ether,(+)-Phillygenin,Phillygenol,Sylvatesmin,Forsythigenol,连翘脂素
Target: Reactive Oxygen Species
Crocin II
Cat.No: T3779
Synonym: Crocin 2,西红花苷II,Crocetin gentiobiosylglucosyl ester,藏红花,Tricrocin,Crocin B
Target: Caspase, COX, NO Synthase
Kuwanon A
Cat.No: TQ0301
Synonym:
Target: NO Synthase
CAFESTOL
Cat.No: T5727
Synonym: 咖啡醇,咖啡油醇
Target: ERK, NF-κB, COX, PGE Synthase
Thiamine monochloride
Cat.No: T2O2741
Synonym: Thiamine chloride,Vitamin B1
Target: Others, Antioxidant, Endogenous Metabolite, Antibacterial
Folic acid
Cat.No: T0062
Synonym: Folate,Vitamin B9,Pteroylglutamic acid,Vitamin M,叶酸,Folacin
Target: DNA/RNA Synthesis, Endogenous Metabolite
Pyridoxylamine
Cat.No: T12588
Synonym: pyridoxamine,吡多胺
Target: Endogenous Metabolite
Dibutyl sebacate
Cat.No: T8010
Synonym: Dibutyl decanedioate,癸二酸二丁酯
Target: Others
Anthragallol
Cat.No: T30086
Synonym: Anthragallic acid,1,2,3-Trihydroxyanthraquinone
Target: Others
N-Acetyltyramine
Cat.No: T37341
Synonym:
Target: Antibacterial
Epoxylinalool
Cat.No: T8014
Synonym: 氧化芳樟醇,2-(2-Hydroxy-2-Propyl)-5-Methyl-5-Vinyltetrahydrofuran
Target: Others
Anhydronotoptol
Cat.No: TN6985
Synonym:
Target: NO Synthase
5,15-Diacetyl-3-benzoyllathyrol
Cat.No: T4S2014
Synonym: ,大戟因子L3,二乙酰基苯甲酰基香豌豆醇,5,15-二乙酰基-3-苯甲酰千金子二萜醇;千金二萜醇二乙酰苯甲酰酯,Euphorbia factor L3
Target: Others
Hulupinic acid
Cat.No: TN4228
Synonym:
Target: NO Synthase
2'-Deoxycytidine-5'-diphosphate trisodium
Cat.No: T4972
Synonym: dCDP,2'-脱氧胞苷-5'-二磷酸三钠盐
Target: Endogenous Metabolite
Epibetulinic acid
Cat.No: T2S0765
Synonym:
Target: NO Synthase, Prostaglandin Receptor
Noricaritin
Cat.No: T2S2150
Synonym: 诺里卡汀,去甲淫羊藿黄素
Target: Others
(E)-Naringenin chalcone
Cat.No: T2S2173
Synonym: Isosalipurpol,柚皮苷查尔酮,Chalconaringenin,trans-2'4'6'4-tetrahydroxychalcone,柚皮素查耳酮
Target: Others
Darutoside
Cat.No: T3S1944
Synonym: Darutin,豯莶苷
Target: Others
Hexahydrofarnesyl acetone
Cat.No: T8249
Synonym: 植酮,Phytone
Target: Others, Antibacterial
2,6-Dimethylpyrazine
Cat.No: T38475
Synonym:
Target: Others
Adipic acid
Cat.No: T2228
Synonym:
Target: Others, Endogenous Metabolite
Xanthosine
Cat.No: TMO2681
Synonym: 9-Beta-D-Ribofuranosylxanthine,黄嘌呤核苷,Xanthine riboside
Target: Others, Endogenous Metabolite
Vanillic Acid
Cat.No: T9115
Synonym: 4-hydroxy-3-methoxybenzoic acid,Acide vanillique,香草酸,Vanillate
Target: Others, NF-κB, Endogenous Metabolite, Antibacterial
Peimine
Cat.No: T6S0107
Synonym: 贝母素甲,Wanpeinine A,Dihydroisoimperialine,Verticine,贝母甲素
Target: Others
Demethylsuberosin
Cat.No: T5774
Synonym: 7-去甲基软木花椒素,7-demethylsuberosin
Target: Prostaglandin Receptor
p-Hydroxycinnamic acid
Cat.No: T7053
Synonym: p-Coumaric acid,p-Cumaric acid,p-Hydroxy-cinnamic acid,对羟基肉桂酸,NSC 59260
Target: Thrombin, Endogenous Metabolite, Prostaglandin Receptor
Methyl 5-hydroxypyridine-2-carboxylate
Cat.No: T40388
Synonym:
Target: Others
L-Hydroxyproline
Cat.No: T2A2476
Synonym: 羟脯氨酸,trans-4-Hydroxy-L-proline,L-Hydroxyprolin,Trans-4-Hydroxyproline
Target: Endogenous Metabolite
Deoxyandrographolide
Cat.No: TQ0218
Synonym: 去氧穿心莲内酯,14-deoxyandrographolide
Target: IL Receptor, TNF
Camalexin
Cat.No: T10668
Synonym:
Target: Reactive Oxygen Species, ROS, Antibacterial, Antifungal
Allitol
Cat.No: T3756
Synonym: Allodulcit,蒜糖醇,Allodulcitol,d-allitol
Target: Others
α-Humulene
Cat.No: TN1373
Synonym: Alpha-caryophyllene,ALPHA-律草烯
Target: TNF, NOS, COX
Methyl 3,4,5-trimethoxybenzoate
Cat.No: T0572
Synonym: Methyl gallate trimethyl ether,Methyl EudesMate,3,4,5-Trimethoxybenzoic acid methyl ester,Methyl tri-O-methylgallate,甲氧苄啶杂质H,Trimethylgallic acid methyl ester
Target: Others, Antioxidant
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Cat. No. Product Name Species Expression System
TMPH-00735 LuxS Protein, E. coli, Recombinant (His & Myc)

luxS,S-ribosylhomocysteine lyase,Autoinducer-2 productio...

E. coli E. coli
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
TMPH-00734 LuxS Protein, E. coli, Recombinant (His)

AI-2 synthesis protein,Autoinducer-2 production pro...

E. coli E. coli
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). LuxS Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. Th...
TMPJ-00235 TPO Protein, Human, Recombinant (His)

Megakaryocyte growth and development factor,C-mpl ligand,Thr...

Human HEK293 Cells
Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets. TPO stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets. Lineage-specific cytokine affects the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physi...
TMPH-02569 WISP2/CCN5 Protein, Mouse, Recombinant (His)

Ccn5,Connective tissue growth factor-like protein,CCN family...

Mouse P. pastoris (Yeast)
May play an important role in modulating bone turnover. Promotes the adhesion of osteoblast cells and inhibits the binding of fibrinogen to integrin receptors. In addition, inhibits osteocalcin production.
TMPK-00047 IFN gamma Protein, Human, Recombinant (His & Avi)

IFN gamma,interferon,Interferon-γ,γ,IFI,干扰素,Interferon-gamma...

Human HEK293 Cells
Interferon-gamma (IFN gamma) is a cytokine that plays physiologically important roles in promoting innate and adaptive immune responses. The absence of IFN gamma production or cellular responsiveness in humans and experimental animals significantly predisposes the host to microbial infection, a result that validates the physiologic importance of this cytokine in preventing infectious disease. IFN gamma Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi ...
TMPJ-00387 IL-4R alpha Protein, Mouse, Recombinant (hFc)

Soluble IL-4R-alpha,Interleukin-4 receptor subunit alpha,Sol...

Mouse HEK293 Cells
Interleukin-4 receptor subunit alpha(IL-4RA), alos known as Soluble IL-4 receptor subunit alpha, belongs to the type I cytokine receptor family and type 4 subfamily. It expressed in both Th1 and Th2 cells. It functions as receptor for both interleukin 4 and interleukin 13 and couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and chemokine and mucus production at sites of allergic ...
TMPY-01648 TREML2 Protein, Human, Recombinant (His)

TLT2,dJ238O23.1,triggering receptor expressed on myeloid cel...

Human HEK293 Cells
Trem-like transcript 2 protein, also known as Triggering receptor expressed on myeloid cells-like protein 2, TREML2 and TLT2, is a single-pass type I membrane protein that contains one Ig-like V-type (immunoglobulin-like) domain. TREML2 is detected in cultured B cells, T cell leukemia and monocyte leukemia. TREML2 is expressed constitutively on CD8 T-cells and induced on CD4 T-cells after activation. TREML2 is a cell surface receptor that may play a role in the innate and adaptive immune respons...
TMPJ-00327 M-CSF/CSF1 Protein, Human, Recombinant (His)

Lanimostim,M-CSF,CSF-1,MCSF,CSF1,集落刺激因子,Macrophage Colony-St...

Human HEK293 Cells
Macrophage Colony-Stimulating Factors (m-csf) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and themonocytes-macrophages. CSF-1 promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It also plays an important role in the regulation of osteoclast proliferation and differentiation, the regulatio...
TMPY-03407 NQO1 Protein, Human, Recombinant (His)

NAD(P)H dehydrogenase, quinone 1,NMORI,DIA4,QR1,NMOR1,DTD,DH...

Human E. coli
NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-electron reduction of quinones that results in the production of radical species. Mutations in the NQO1 gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered ex...
TMPJ-01172 IL-17 Protein, Mouse, Recombinant (His)

CTLA8,IL-17,IL-17A,Interleukin-17A,CTLA-8,Cytotoxic T-Lympho...

Mouse HEK293 Cells
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Mature mouse IL-17A shares 61% and 89% amino acid sequence identity with human and rat IL-17A, respectively. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumato...
TMPJ-01467 Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His)

Oncostatin-M,OSM

Human E. coli
Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. OSM encodes a growth regulator, which Inhibits the proliferation of a number of tumor cell lines. It stimulates proliferation of AIDS-KS cells. OSM regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. OSM is considered as a pleiotropic cytokine that initiates its biological ac...
TMPJ-01466 Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His)

OPG,Tumor Necrosis Factor Receptor Superfamily Member 11B,OC...

Human HEK293 Cells
TNFRSF11B is a secreted protein, containing 2 death domains and 4 TNFR-Cys repeats. TNFRSF11B is a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL). By binding RANKL, TNFRSF11B inhibits nuclear kappa B (NF-κB) which is a central and rapid acting transcription factor for immune-related genes, and a key regulator of inflammation, innate immunity, and cell survival and differentiation. TNFRSF11B levels are influenced by voltage-dependent calcium channelsCav1.2. TNF...
TMPY-02779 Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)

thyroid peroxidase,MSA,TPX,TDH2A

Human Baculovirus Insect Cells
Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. It used to be taken as the formerly so-called `microsomal antigen` several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two i...
TMPY-02904 TLR4 Protein, Human, Recombinant (His)

TLR-4,TOLL,toll-like receptor 4,ARMD10,TLR4,CD284

Human Baculovirus Insect Cells
TLR4, also known as TLR-4, is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. TLR4 is most abundantly expressed...
TMPY-02030 CD82 Protein, Human, Recombinant (His)

CD82 molecule,SAR2,R2,KAI-1,4F9,KAI1,C33,TSPAN27,ST6,IA4,GR1...

Human HEK293 Cells
CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signalling. Downregulation of CD82 expression is associated with the advanced stages of many human cancers and correlates with the acquisition of metastatic potential. Recent stud...
TMPY-02219 Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His)

NS1 Protein

H1N1 E. coli
The NS1 Influenza protein is created by the internal protein-encoding, linear negative-sense, single-stranded RNA, NS gene segment and which also codes for the nuclear export protein or NEP, formerly referred to as the NS2 protein, which mediates the export of vRNPs. The non-structural (NS1) protein is found in Influenzavirus A, Influenzavirus B, and Influenzavirus C. The non-structural (NS1) protein of the highly pathogenic avian H5N1 viruses circulating in poultry and waterfowl in Southeast As...
TMPK-00076 IL-18 Protein (Primary Amine Labeling), Human, Recombinant, Biotinylated

白介素,IL-18,白细胞介素,IL18,IL-1F4,IL-1g,IL1F4,IL-1 gamma,Interleuk...

Human E. coli
Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation.
TMPK-00661 IL-22 Protein, Cynomolgus, Recombinant (His)

TIFIL-23,IL-22,IL-D110,IL-TIF,TIFa,Interleukin-22,Cytokine Z...

Cynomolgus HEK293 Cells
The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeability, production of mucus and antimicrobial proteins (AMPs), and complement production. IL-22 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 17.69 kDa and the accession number is G7PHZ7.
TMPH-02806 Nav3 Protein, Mouse, Recombinant (His)

Neuron navigator 3,Pore membrane and/or filament-interacting...

Mouse E. coli
May regulate IL2 production by T-cells. May be involved in neuron regeneration.
TMPH-02585 ACOD1 Protein, Mouse, Recombinant (His & Myc)

Cis-aconitate decarboxylase,Cis-aconitic acid decarboxylase,...

Mouse Baculovirus Insect Cells
Cis-aconitate decarboxylase that catalyzes production of itaconate and is involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; ACOD1-mediated itaconic acid production contributes to the anti...
TMPK-01194 IL-22 Protein, Mouse, Recombinant (His & Avi), Biotinylated

IL-22,Cytokine Zcyto18,白细胞介素,IL-TIF,白介素,Interleukin-22,TIFIL...

Mouse E. coli
The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeability, production of mucus and antimicrobial proteins (AMPs), and complement production. IL-22 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with N-His-Avi tag. The predicted molecular weight is 19.7 kDa and the accession number i...
TMPJ-00070 IL-18 Protein, Human, Recombinant (His)

GIF,IL-1 γ,白细胞介素,Iboctadekin,Interleukin-18,Interferon γ-ind...

Human HEK293 Cells
Interleukin-18 is a secreted protein and it belongs to the IL-1 family. IL-18 is a proinflammatory cytokine and produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL-4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. After...
TMPH-01547 Interferon alpha 21/IFNA21 Protein, Human, Recombinant (His)

IFNA21,Interferon alpha-21,Interferon alpha-F

Human E. coli
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
TMPH-01544 Interferon alpha 14/IFNA14 Protein, Human, Recombinant (His & SUMO)

Interferon alpha-H,Interferon alpha-14,Interferon lambda-2-H...

Human E. coli
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
TMPH-02299 UGP2 Protein, Human, Recombinant (His & SUMO)

UDP-glucose pyrophosphorylase,UTP--glucose-1-phosphate uridy...

Human E. coli
UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.
TMPH-02883 RBFOX3 Protein, Mouse, Recombinant (His & Myc)

Neuronal nuclei antigen,Rbfox3,RNA binding protein fox-1 hom...

Mouse E. coli
Pre-mRNA alternative splicing regulator. Regulates alternative splicing of RBFOX2 to enhance the production of mRNA species that are targeted for nonsense-mediated decay (NMD).
TMPH-03214 OX40L/TNFSF4 Protein, Rabbit, Recombinant (His & Myc)

Tumor necrosis factor ligand superfamily member 4,TNFSF4,OX4...

Rabbit P. pastoris (Yeast)
Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production. TNFSF4 Protein, Rabbit, Recombinant (His & Myc) is expressed in yeast with C-6xHis, Myc tag. The predicted molecular weight is 19.8 kDa and the accession number is O02765.
TMPH-03215 OX40L/TNFSF4 Protein, Rabbit, Recombinant (hFc)

TNFSF4,OX40 ligand,Tumor necrosis factor ligand superfamily ...

Rabbit HEK293 Cells
Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production. TNFSF4 Protein, Rabbit, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is O02765.
TMPJ-00617 IL-33 Protein, Rhesus macaque, Recombinant (His)

Interleukin-33,IL1F11,IL33,白介素,白细胞介素,IL-1F11,Interleukin-1 F...

Rhesus E. coli
Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes, but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2)-associated cytokines. IL-33 is a cytokine that mediates its biological effects by binding to and signals through IL1RL1/ST2 and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-κB and MAP kinase signaling pathways...
TMPH-00784 Intimin Protein, Hafnia alvei, Recombinant (His & SUMO)

Outer membrane protein,Attaching and effacing protein,Intimi...

Hafnia alvei E. coli
Necessary for the production of attaching and effacing lesions on tissue culture cells. Intimin Protein, Hafnia alvei, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 46.1 kDa and the accession number is P52869.
TMPH-02570 WISP2/CCN5 Protein, Mouse, Recombinant (His & SUMO)

CCN family member 5,Connective tissue growth factor-like pro...

Mouse E. coli
May play an important role in modulating bone turnover. Promotes the adhesion of osteoblast cells and inhibits the binding of fibrinogen to integrin receptors. In addition, inhibits osteocalcin production.
TMPH-03216 OX40L/TNFSF4 Protein, Rabbit, Recombinant (His)

Tumor necrosis factor ligand superfamily member 4,TNFSF4,OX4...

Rabbit E. coli
Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production. TNFSF4 Protein, Rabbit, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 20.1 kDa and the accession number is O02765.
TMPH-03116 IL-4R Protein, Pig, Recombinant (His)

IL4R,Interleukin-4 receptor subunit alpha

Sus scrofa (Pig) E. coli
Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2. IL-4R Protein, Pig, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted mo...
TMPH-01347 FSHR Protein, Human, Recombinant (E. coli, His)

Follicle-stimulating hormone receptor,Follitropin receptor,F...

Human E. coli
G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. FSHR Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 44.0 kDa and the accession number is P23945.
TMPK-00077 EPO/Erythropoietin Protein, Human, Recombinant

EPO,MVCD2,红细胞生长素,Epoetin,Erythropoietin,EP

Human HEK293 Cells
Erythropoietin (EPO) is a circulating hormone conventionally considered to be responsible for erythropoiesis. In addition to facilitating red blood cell production, EPO has pluripotent potential, such as for cognition improvement, neurogenesis, and anti-fibrotic, anti-apoptotic, anti-oxidative, and anti-inflammatory effects.
TMPY-05058 TMX1 Protein, Human, Recombinant (mFc)

thioredoxin-related transmembrane protein 1,PDIA11,TXNDC,TXN...

Human HEK293 Cells
As a thiol-based tumor suppressor, TMX1 increases mitochondrial ATP production and apoptosis progression. TMX1 is the first example of a topology-specific client protein redox catalyst acting both in the folding and in the degradative pathways.
TMPH-01603 Lanosterol synthase/LSS Protein, Human, Recombinant (His)

Lanosterol synthase,LSS,2,3-epoxysqualene--lanosterol cyclas...

Human E. coli
Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Through the production of lanosterol may regulate lens protein aggregation and increase transparency.
TMPY-03172 Argininosuccinate lyase Protein, Human, Recombinant (His & GST)

ASAL,argininosuccinate lyase,ASL

Human Baculovirus Insect Cells
The recycling of citrulline by argininosuccinate synthase 1 (ASS1) and argininosuccinate lyase (ASL) is crucial to maintain arginine availability and nitric oxide (NO) production. Nitric oxide (NO) plays an established role in numerous physiological and pathological processes, but the specific cellular sources of NO in disease pathogenesis remain unclear, preventing the implementation of NO-related therapy. Argininosuccinate lyase (ASL) is the only enzyme able to produce arginine, the substrate ...
TMPH-02685 GPHB5 Protein, Mouse, Recombinant (His & Myc)

Glycoprotein hormone beta-5,Thyrostimulin subunit beta,Gphb5

Mouse E. coli
Functions as a heterodimeric glycoprotein hormone with GPHA2 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid cell metabolism.
TMPK-00316 IL-18R alpha Protein, Human, Recombinant (His & Avi)

CD218a,IL-18 R1,IL1RRP,IL-18Ra,IL-18 R alpha,IL-1 Rrp,IL-1 R...

Human HEK293 Cells
Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation. IL-18R alpha Pr...
TMPK-00136 ULBP-2 Protein, Human, Recombinant (His & Avi)

ALCAN-α,RAET1L,NKG2D ligand 2,ALCAN-alpha,N2DL2,ULBP-2/5/6,R...

Human HEK293 Cells
ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway, mediating natural killer cell cytotoxicity.
TMPK-00512 IL-18R alpha Protein, Cynomolgus, Recombinant (aa 22-329, His)

IL18R1,IL-1 Rrp,CD218a,IL18Ra,IL-18Ra,IL-18 R alpha,IL1RRP,I...

Cynomolgus HEK293 Cells
Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation. IL-18R alpha Pr...
TMPK-00317 IL-18R alpha Protein, Human, Recombinant (His & Avi), Biotinylated

IL-18 R α,IL-1 R5,IL18Ra,IL-18Ra,CD218a,IL-18 R alpha,IL-1 R...

Human HEK293 Cells
Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation. IL-18R alpha Pr...
TMPH-01546 Interferon alpha 17/IFNA17 Protein, Human, Recombinant (His)

Interferon alpha-T,Interferon alpha-88,IFNA17,Interferon alp...

Human E. coli
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. Interferon alpha 17/IFNA17 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 25.3 kDa and the accession number is P01571.
TMPH-01545 Interferon alpha 16/IFNA16 Protein, Human, Recombinant (His)

Interferon alpha-16,Interferon alpha-WA,IFNA16

Human E. coli
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. Interferon alpha 16/IFNA16 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.4 kDa and the accession number is P05015.
TMPJ-01056 IL-18 Protein, Mouse, Recombinant (His)

Interferon γ-inducing factor,Interleukin-1 gamma,Igif,IL-1 g...

Mouse E. coli
Interleukin-18 (IL-18)is a protein which belongs to the IL-1 family. It is expressed as a 24 kDa precursor by endothelial and epithelial cells, keratinocytes, gamma δ T cells, and phagocytes. Mature mouse IL-18 shares 63% and 91% amino acid sequence identity with mouse and rat IL-18, respectively. IL-18 binds to the widely expressed IL-18 R alpha which recruits IL-18 R beta to form the signaling receptor complex. Its bioactivity is negatively regulated by interactions with IL-18 binding proteins...
TMPH-01348 FSHR Protein, Human, Recombinant (His)

Follitropin receptor,FSHR,Follicle-stimulating hormone recep...

Human HEK293 Cells
G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. FSHR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 43.5 kDa and the accession number is P23945.
TMPH-03481 FimH Protein, Salmonella typhimurium, Recombinant (His & Myc)

Protein FimH,Type 1 fimbrin D-mannose specific adhesin,fimH

Salmonella typhimurium E. coli
Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). A mannose-binding adhesin. FimH Protein, Salmonella typhimurium, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 41.2 kDa and the accession number is P37925.
TMPY-04170 DEFB1 Protein, Human, Recombinant (hFc)

DEFB101,defensin, β1,β Defensin 1/DEFB1,defensin, beta 1,DEF...

Human HEK293 Cells
The DEFB1 gene, encoding for the constitutively expressed human beta-defensin 1 (hBD1) antimicrobial peptide is a potential candidate when studying genetic susceptibility to caries. DEFB1 genetic variations have been reported as contributing to hBD1 production impairment, leading to a greater susceptibility to be infected by oral pathogens, also leading to periodontitis. To counteract host immunity, Cryptosporidium parvum has evolved multiple strategies to suppress host antimicrobial defense. On...
TMPJ-00611 SFP Protein, B.subtilis, Recombinant (His)

Surfactin synthase-activating enzyme,sfp,lpa-8,4'-phosphopan...

Bacillus subtilis E. coli
The Bacillus subtilis enzyme Sfp, required for production of the lipoheptapeptide antibiotic surfactin, posttranslationally phosphopantetheinylates a serine residue in each of the seven peptidyl carrier protein domains of the first three subunits (SrfABC) of surfactin synthetase to yield docking sites for amino acid loading and peptide bond formation.
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重组蛋白

LuxS Protein, E. coli, Recombinant (His & Myc)
Cat.No: TMPH-00735
Species: E. coli
Expression System: E. coli
LuxS Protein, E. coli, Recombinant (His)
Cat.No: TMPH-00734
Species: E. coli
Expression System: E. coli
TPO Protein, Human, Recombinant (His)
Cat.No: TMPJ-00235
Species: Human
Expression System: HEK293 Cells
WISP2/CCN5 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02569
Species: Mouse
Expression System: P. pastoris (Yeast)
IFN gamma Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00047
Species: Human
Expression System: HEK293 Cells
IL-4R alpha Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00387
Species: Mouse
Expression System: HEK293 Cells
TREML2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01648
Species: Human
Expression System: HEK293 Cells
M-CSF/CSF1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00327
Species: Human
Expression System: HEK293 Cells
NQO1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03407
Species: Human
Expression System: E. coli
IL-17 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01172
Species: Mouse
Expression System: HEK293 Cells
Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPJ-01467
Species: Human
Expression System: E. coli
Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His)
Cat.No: TMPJ-01466
Species: Human
Expression System: HEK293 Cells
Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)
Cat.No: TMPY-02779
Species: Human
Expression System: Baculovirus Insect Cells
TLR4 Protein, Human, Recombinant (His)
Cat.No: TMPY-02904
Species: Human
Expression System: Baculovirus Insect Cells
CD82 Protein, Human, Recombinant (His)
Cat.No: TMPY-02030
Species: Human
Expression System: HEK293 Cells
Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His)
Cat.No: TMPY-02219
Species: H1N1
Expression System: E. coli
IL-18 Protein (Primary Amine Labeling), Human, Recombinant, Biotinylated
Cat.No: TMPK-00076
Species: Human
Expression System: E. coli
IL-22 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00661
Species: Cynomolgus
Expression System: HEK293 Cells
Nav3 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02806
Species: Mouse
Expression System: E. coli
ACOD1 Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02585
Species: Mouse
Expression System: Baculovirus Insect Cells
IL-22 Protein, Mouse, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-01194
Species: Mouse
Expression System: E. coli
IL-18 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00070
Species: Human
Expression System: HEK293 Cells
Interferon alpha 21/IFNA21 Protein, Human, Recombinant (His)
Cat.No: TMPH-01547
Species: Human
Expression System: E. coli
Interferon alpha 14/IFNA14 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01544
Species: Human
Expression System: E. coli
UGP2 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-02299
Species: Human
Expression System: E. coli
RBFOX3 Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02883
Species: Mouse
Expression System: E. coli
OX40L/TNFSF4 Protein, Rabbit, Recombinant (His & Myc)
Cat.No: TMPH-03214
Species: Rabbit
Expression System: P. pastoris (Yeast)
OX40L/TNFSF4 Protein, Rabbit, Recombinant (hFc)
Cat.No: TMPH-03215
Species: Rabbit
Expression System: HEK293 Cells
IL-33 Protein, Rhesus macaque, Recombinant (His)
Cat.No: TMPJ-00617
Species: Rhesus
Expression System: E. coli
Intimin Protein, Hafnia alvei, Recombinant (His & SUMO)
Cat.No: TMPH-00784
Species: Hafnia alvei
Expression System: E. coli
WISP2/CCN5 Protein, Mouse, Recombinant (His & SUMO)
Cat.No: TMPH-02570
Species: Mouse
Expression System: E. coli
OX40L/TNFSF4 Protein, Rabbit, Recombinant (His)
Cat.No: TMPH-03216
Species: Rabbit
Expression System: E. coli
IL-4R Protein, Pig, Recombinant (His)
Cat.No: TMPH-03116
Species: Sus scrofa (Pig)
Expression System: E. coli
FSHR Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPH-01347
Species: Human
Expression System: E. coli
EPO/Erythropoietin Protein, Human, Recombinant
Cat.No: TMPK-00077
Species: Human
Expression System: HEK293 Cells
TMX1 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-05058
Species: Human
Expression System: HEK293 Cells
Lanosterol synthase/LSS Protein, Human, Recombinant (His)
Cat.No: TMPH-01603
Species: Human
Expression System: E. coli
Argininosuccinate lyase Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-03172
Species: Human
Expression System: Baculovirus Insect Cells
GPHB5 Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02685
Species: Mouse
Expression System: E. coli
IL-18R alpha Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00316
Species: Human
Expression System: HEK293 Cells
ULBP-2 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00136
Species: Human
Expression System: HEK293 Cells
IL-18R alpha Protein, Cynomolgus, Recombinant (aa 22-329, His)
Cat.No: TMPK-00512
Species: Cynomolgus
Expression System: HEK293 Cells
IL-18R alpha Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00317
Species: Human
Expression System: HEK293 Cells
Interferon alpha 17/IFNA17 Protein, Human, Recombinant (His)
Cat.No: TMPH-01546
Species: Human
Expression System: E. coli
Interferon alpha 16/IFNA16 Protein, Human, Recombinant (His)
Cat.No: TMPH-01545
Species: Human
Expression System: E. coli
IL-18 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01056
Species: Mouse
Expression System: E. coli
FSHR Protein, Human, Recombinant (His)
Cat.No: TMPH-01348
Species: Human
Expression System: HEK293 Cells
FimH Protein, Salmonella typhimurium, Recombinant (His & Myc)
Cat.No: TMPH-03481
Species: Salmonella typhimurium
Expression System: E. coli
DEFB1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04170
Species: Human
Expression System: HEK293 Cells
SFP Protein, B.subtilis, Recombinant (His)
Cat.No: TMPJ-00611
Species: Bacillus subtilis
Expression System: E. coli
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Cat. No. Product Name Target Signaling Pathways
T40376 L-Phenylalanine-15N

L-苯丙氨酸 15N,(S)-2-Amino-3-phenylpropionic acid-15N,L-Phenylalanine-15N

Calcium Channel Membrane transporter/Ion channel; Metabolism
L-Phenylalanine-15N ((S)-2-Amino-3-phenylpropionic acid-15N) 是 15N 标记的 L-Phenylalanine。L-Phenylalanine 是从大肠杆菌中分离出来的一种必需氨基酸。 L-Phenylalanine 广泛用于食品香精和药物的生产。
T12485 Pirfenidone-d5

AMR69 D5,Pirfenidone D5

Others Others
Pirfenidone D5 is a deuterium labeled Pirfenidone. Pirfenidone is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells.
T71328 Theobromine-d6

Theobromine-d6 is intended for use as an internal standard for the quantification of theobromine by GC- or LC-MS. Theobromine is a methylxanthine alkaloid and derivative of caffeine that has been found in cocoa beans and has diverse biological activities. It is an adenosine A1 receptor antagonist. Theobromine increases AMPK phosphorylation and inhibits adipocyte differentiation, ERK and JNK phosphorylation, and IL-6 and TNF-α production in 3T3-L1 preadipocytes cultured in differentiation medium....
TMIH-0102 Avatrombopag-d8

Avatrombopag-d8 是 Avatrombopag 的氘代化合物。Avatrombopag 的 CAS 号为 570406-98-3。Avatrombopag 是一种新型口服血小板生成素 (TPO) 受体激动剂,可激活 TPO 受体并增加巨核细胞增殖/分化和血小板生成。
T71212 Lornoxicam-d4

Lornoxicam-d4 is intended for use as an internal standard for the quantification of lornoxicam by GC- or LC-MS. Lornoxicam is a COX inhibitor and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory and analgesic properties. It inhibits production of thromboxane B2 from arachidonic acid in HEL human erythroleukemic cells, which endogenously express COX-1, as well as inhibits LPS-induced formation of prostaglandin F1α from arachidonic acid in Mono-Mac-6 cells, which endogenously e...
TMIJ-0107 Adipic Acid-d8

Adipic Acid-d8 是 Adipic Acid 的氘代化合物。Adipic Acid 的 CAS 号为 124-04-9。Adipic acid 是一种生产尼龙的前体。它被发现与 HMG-CoA 裂解酶缺乏症,肉毒碱激酶缺乏症,中链酰基脱氢酶缺乏症相关,这些都是天生代谢异常导致的。
TMID-0012 Ethyl-d5 Vanillin

Ethyl-d5 Vanillin 是 Ethyl Vanillin 的氘代化合物。Ethyl Vanillin 的 CAS 号为 121-32-4。Ethyl vanillin 是一种食用香料,效果是 Vanillin 的三倍,可用于巧克力的生产。
TMIJ-0209 Beclomethasone-17-Monopropionate-d3

Beclomethasone-17-Monopropionate-d3 是 Beclomethasone-17-Monopropionate 的氘代化合物。Beclomethasone-17-Monopropionate 的 CAS 号为 5534-18-9。
TMIJ-0273 Sulindac EP Impurity C-d3

Sulindac EP Impurity C-d3 是 Sulindac EP Impurity C 的氘代化合物。Sulindac EP Impurity C 的 CAS 号为 32004-67-4。
TMIJ-0419 Ethylene thiourea-d4

Ethylene thiourea-d4 是 Ethylene thiourea 的氘代化合物。Ethylene thiourea 的 CAS 号为 96-45-7。Ethylene thiourea 是一种用于水果和蔬菜生产的农药。它还用作基于质子化学交换依赖性饱和转移的 MRI 研究的新型造影剂。
TMIJ-0373 Biotin-d2

Biotin-d2 是 Biotin 的氘代化合物。Biotin 的 CAS 号为 58-85-5。Biotin 是一种水溶性B族维生素,是细胞生长、脂肪酸产生以及脂肪和氨基酸代谢所必需的。
TMIJ-0347 Phenol-d6

Phenol-d6 是 Phenol 的氘代化合物。Phenol 的 CAS 号为 108-95-2。Phenol 是一种有毒的无色结晶固体,具有类似医院气味的甜焦油气味。它通常用作防腐剂和消毒剂。它对包括一些真菌和病毒在内的多种微生物有活性,但对孢子只有缓慢的效果。它已被用于消毒皮肤和缓解瘙痒。苯酚还用于制备化妆品,包括防晒霜、染发剂和亮肤制剂。它还用于生产药物(它是工业生产阿司匹林的原料)、除草剂和合成树脂。
TMIJ-0162 Dexamethasone-d4

Dexamethasone-d4 是 Dexamethasone 的氘代化合物。Dexamethasone 的 CAS 号为 50-02-2。Dexamethasone是一种糖皮质激素受体激动剂和一种 IL 受体调节剂。在脂多糖诱导的巨噬细胞炎症反应中,它抑制含有炎性 microRNA-155 的外泌体的产生。
T71306 Gemfibrozil-d6

Gemfibrozil-d6 is intended for use as an internal standard for the quantification of gemfibrozil by GC- or LC-MS. Gemfibrozil is a peroxisome proliferator-activated reporter α and PPARγ agonist. In vivo, gemfibrozil reduces serum total cholesterol, triglyceride, and LDL levels in a rat model of high-cholesterol diet-induced hyperlipidemia. Gemfibrozil reduces atherosclerotic plaque area, superoxide production, and expression of the genes encoding the NF-κB subunit p65 and chemokine (C-C) motif l...
T71286 Guaifenesin-d3

Guaifenesin-d3 is intended for use as an internal standard for the quantification of guaifenesin by GC- or LC-MS. Guaifenesin is an expectorant. It inhibits production of mucin 5AC (MUC5AC), reduces mucus viscosity and elasticity, and increases the mucociliary transport rate of endogenous particles in primary human tracheobronchial epithelial cells in a concentration-dependent manner. Guaifenesin increases phenol red secretion, a marker of expectorant activity, in rats.3 Formulations containing ...
TMIJ-0416 Phenol-d5 (2,3,4,5,6-d5)

Phenol-d5 (2,3,4,5,6-d5) 是 Phenol 的氘代化合物。Phenol 的 CAS 号为 108-95-2。Phenol 是一种有毒的无色结晶固体,具有类似医院气味的甜焦油气味。它通常用作防腐剂和消毒剂。它对包括一些真菌和病毒在内的多种微生物有活性,但对孢子只有缓慢的效果。它已被用于消毒皮肤和缓解瘙痒。苯酚还用于制备化妆品,包括防晒霜、染发剂和亮肤制剂。它还用于生产药物(它是工业生产阿司匹林的原料)、除草剂和合成树脂。
TMIJ-0103 Suplatast Tosylate-d5

Suplatast Tosylate-d5 是 Suplatast Tosylate 的氘代化合物。Suplatast Tosylate 的 CAS 号为 94055-76-2。Suplatast Tosilate 是一种口服有活性的 Th2 细胞因子抑制剂,能够阻碍 Th2 细胞产生 IL-4 和 IL-5 ,并对 IgE 的合成具有抑制作用。它是一种抗过敏剂,它具有抗纤维化、抗哮喘及抗炎特性。
T71285 Metaxalone-d6

Metaxalone-d6 is intended for use as an internal standard for the quantification of metaxalone by GC-or LC-MS. Metaxalone is a skeletal muscle relaxant. It inhibits the proliferation of, and induces apoptosis in, RAW 264.7 cells in vitro when used at concentrations ranging from 1 to 100 µM. Metaxalone also reduces LPS-induced increases in COX-1, COX-2, and NF-kB levels and inhibits LPS-induced production of TNF-α, IL-6, and prostaglandin E2 in RAW 264.7 cells. Formulations containing metaxalone ...
TMIJ-0207 (S)-Ketoprofen-d3

(S)-Ketoprofen-d3 是 (S)-Ketoprofen 的氘代化合物。(S)-Ketoprofen 的 CAS 号为 22161-81-5。S-(+)-Ketoprofen 抑制COX-1和COX-2的IC50值分别为 1.9 和 27 nM。
TMIJ-0435 Octanoic Acid-d15

Octanoic Acid-d15 是 Octanoic Acid 的氘代化合物。Octanoic Acid 的 CAS 号为 124-07-2。Caprylic acid天然存在于椰子和母乳中。它是一种油性液体,带有些许腐臭味,能用于酯类香料和染料的生产。
TMIJ-0208 Beclomethasone Dipropionate-d6

Beclomethasone Dipropionate-d6 是 Beclomethasone Dipropionate 的氘代化合物。Beclomethasone Dipropionate 的 CAS 号为 5534-09-8。Betamethasone dipropionate是具有口服活性的糖皮质激素,具有抗炎和免疫抑制作用。它是Betamethasone 的前体药物,Betamethasone 是 LPS 诱导的炎症及 MMP 释放的抑制剂。
TMIJ-0090 L-Carnitine-d9

L-Carnitine-d9 是 L-Carnitine 的氘代化合物。L-Carnitine 的 CAS 号为 541-15-1。L-carnitine 是一种人内源性分子,在人体内以蛋氨酸和赖氨酸为底物进行生物合成,并参与脂肪酸代谢。L-Carnitine 将长链脂肪酰辅酶A转运到线粒体。L-Carnitine 能够改善许多先天性代谢错误的代谢失衡。
TMIJ-0081 L-Leucine-d10

L-Leucine-d10 是 L-Leucine 的氘代化合物。L-Leucine 的 CAS 号为 61-90-5。L-Leucine 是必需的支链氨基酸,能够激活mTOR信号通路。
T71143 Ambroxol-d5

Ambroxol-d5 is intended for use as an internal standard for the quantification of ambroxol by GC- or LC-MS. Ambroxol is an expectorant and active metabolite of bromhexine. It decreases short-circuit currents in electrically stimulated isolated canine tracheal epithelial cells when applied submucosally. Ambroxol decreases IL-13-induced production of mucin 5AC (MUC5AC) in primary human airway epithelial cells and inhibits IL-13-induced decreases in the mucociliary transport rate of endogenous part...
TMIJ-0417 2,4-D-d3

2,4-D-d3 是 2,4-D 的氘代化合物。2,4-D 的 CAS 号为 94-75-7。2,4-Dichlorophenoxyacetic acid 是一种合成生长素,用作植物生长调节剂,也用作植物细胞培养基中的补充剂。它是除草剂中的一种活性成分,用于破坏肌动蛋白细胞骨架,以控制根系伸长和细胞生成。
T70186 Methazolamide-d6

Methazolamide-d6 is intended for use as an internal standard for the quantification of methazolamide by GC- or LC-MS. Methazolamide is a carbonic anhydrase inhibitor. It reduces intraocular pressure and cerebrospinal fluid flow in a rat model of glaucoma. Methazolamide reduces electroshock-induced seizures in rats with an ED50 value of 19.2 mg/kg. It also inhibits production of reactive oxygen species (ROS) in a primary cortical neuron (PCN) cellular model of subarachnoid hemorrhage (SAH) and re...
TMIJ-0374 L-Leucine-d3

L-Leucine-d3 是 L-Leucine 的氘代化合物。L-Leucine 的 CAS 号为 61-90-5。L-Leucine 是必需的支链氨基酸,能够激活mTOR信号通路。
T71293 Nifuroxazide-d4

Nifuroxazide-d4 is intended for use as an internal standard for the quantification of nifuroxazide by GC- or LC-MS. Nifuroxazide is a nitrofuran antibiotic. It is active against strains of the enteropathogenic bacteria C. jejuni, Salmonella, Y. enterocolitica, Shigella, and E. coli. It inhibits quorum sensing and virulence factor production in P. aeruginosa. Nifuroxazide inhibits STAT3 activity in a reporter assay and decreases viability of U266 and INA-6 myeloma cells, which have constitutive S...
TMID-0242 Capecitabine-d11

Capecitabine-d11 是 Capecitabine 的氘代化合物。Capecitabine 的 CAS 号为 154361-50-9。Capecitabine 是一种可口服的前药,可由胸苷磷酸化酶催化转变为其活性代谢物 Fluorouracil。
T70882 Orlistat-d3

Orlistat-d3 is intended for use as an internal standard for the quantification of orlistat by GC- or LC-MS. Orlistat is a digestive lipase inhibitor. It inhibits diacylglycerol lipase α (DAGLα), DAGLβ, α/β-hydrolase domain-containing protein 12 (ABHD12), ABHD16A, and platelet-activating factor acetylhydrolase (PAF-AH; IC50s = 0.06, 0.1, 0.08, 0.03, and 0.05 µM, respectively), as well as pancreatic lipase and hormone-sensitive lipase (IC50s = 0.65 and 2.1 µg/ml, respectively) but does not inhibit...
TMID-0056 (±)-Mandelic-2,3,4,5,6-d5 Acid

(±)-Mandelic-2,3,4,5,6-d5 Acid 是 (±)-Mandelic Acid 的氘代化合物。(±)-Mandelic Acid 的 CAS 号为 90-64-2。DL-Mandelic acid 是一种 α-羟基羧酸,有抗菌活性,广泛用作医药和精细化学品的中间体,已用于研究尿路感染和阴道滴虫病,还具有较高的精子固定活性和较低的阴道刺激性。
TMIJ-0317 Nadolol-d9 (Mixture of Diastereomers)

Nadolol-d9 (Mixture of Diastereomers) 是 Nadolol 的氘代化合物。Nadolol 的 CAS 号为 42200-33-9。Nadolol 是一种有机阴离子转运多肽 1A2 (OATP1A2) 的底物,是一种非选择性的、具有口服活性的 β-肾上腺素受体 (β-adrenergic receptors) 阻滞剂,可用于高血压,心绞痛和血管性头痛的研究。
TMIJ-0384 L-Cysteine-d3

L-Cysteine-d3 是 L-Cysteine 的氘代化合物。L-Cysteine 的 CAS 号为 52-90-4。L-Cysteine 是人体非必需的含硫氨基酸。L-Cysteine 对蛋白质合成、解毒和多种代谢功能很重要。L-Cysteine 存在于指甲、皮肤和头发的主要蛋白质-角蛋白中,对胶原蛋白的生成、皮肤弹性和质地都很重要。L-Cysteine 是抗氧化剂谷胱甘肽的一种成分,在辅酶A、肝素和生物素等基本生化物质的代谢中起着重要作用,也是氨基酸牛磺酸的制造所必需的。
T35515 3-Acetyldeoxy Nivalenol-13C17

3-Acetyldeoxy Nivalenol-13C17

3-Acetyldeoxy nivalenol-13C17is intended for use as an internal standard for the quantification of 3-acetyldeoxy nivalenol by GC- or LC-MS. 3-Acetyldeoxy nivalenol is a mycotoxin that has been found inF. graminearum.1In vivo, 3-acetyldeoxy nivalenol (40 mg/kg) induces duodenal and splenic cell necrosis, as well as lethality (LD50= 70 mg/kg) in mice.2 1.Jiao, F., Kawakami, A., and Nakajima, T.Effects of different carbon sources on trichothecene production and Tri gene expression by Fusarium grami...

同位素标记化合物

L-Phenylalanine-15N
Cat.No: T40376
Synonym: L-苯丙氨酸 15N,(S)-2-Amino-3-phenylpropionic acid-15N,L-Phenylalanine-15N
Target: Calcium Channel
Pirfenidone-d5
Cat.No: T12485
Synonym: AMR69 D5,Pirfenidone D5
Target: Others
Theobromine-d6
Cat.No: T71328
Synonym:
Target:
Avatrombopag-d8
Cat.No: TMIH-0102
Synonym:
Target:
Lornoxicam-d4
Cat.No: T71212
Synonym:
Target:
Adipic Acid-d8
Cat.No: TMIJ-0107
Synonym:
Target:
Ethyl-d5 Vanillin
Cat.No: TMID-0012
Synonym:
Target:
Beclomethasone-17-Monopropionate-d3
Cat.No: TMIJ-0209
Synonym:
Target:
Sulindac EP Impurity C-d3
Cat.No: TMIJ-0273
Synonym:
Target:
Ethylene thiourea-d4
Cat.No: TMIJ-0419
Synonym:
Target:
Biotin-d2
Cat.No: TMIJ-0373
Synonym:
Target:
Phenol-d6
Cat.No: TMIJ-0347
Synonym:
Target:
Dexamethasone-d4
Cat.No: TMIJ-0162
Synonym:
Target:
Gemfibrozil-d6
Cat.No: T71306
Synonym:
Target:
Guaifenesin-d3
Cat.No: T71286
Synonym:
Target:
Phenol-d5 (2,3,4,5,6-d5)
Cat.No: TMIJ-0416
Synonym:
Target:
Suplatast Tosylate-d5
Cat.No: TMIJ-0103
Synonym:
Target:
Metaxalone-d6
Cat.No: T71285
Synonym:
Target:
(S)-Ketoprofen-d3
Cat.No: TMIJ-0207
Synonym:
Target:
Octanoic Acid-d15
Cat.No: TMIJ-0435
Synonym:
Target:
Beclomethasone Dipropionate-d6
Cat.No: TMIJ-0208
Synonym:
Target:
L-Carnitine-d9
Cat.No: TMIJ-0090
Synonym:
Target:
L-Leucine-d10
Cat.No: TMIJ-0081
Synonym:
Target:
Ambroxol-d5
Cat.No: T71143
Synonym:
Target:
2,4-D-d3
Cat.No: TMIJ-0417
Synonym:
Target:
Methazolamide-d6
Cat.No: T70186
Synonym:
Target:
L-Leucine-d3
Cat.No: TMIJ-0374
Synonym:
Target:
Nifuroxazide-d4
Cat.No: T71293
Synonym:
Target:
Capecitabine-d11
Cat.No: TMID-0242
Synonym:
Target:
Orlistat-d3
Cat.No: T70882
Synonym:
Target:
(±)-Mandelic-2,3,4,5,6-d5 Acid
Cat.No: TMID-0056
Synonym:
Target:
Nadolol-d9 (Mixture of Diastereomers)
Cat.No: TMIJ-0317
Synonym:
Target:
L-Cysteine-d3
Cat.No: TMIJ-0384
Synonym:
Target:
3-Acetyldeoxy Nivalenol-13C17
Cat.No: T35515
Synonym: 3-Acetyldeoxy Nivalenol-13C17
Target:
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