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Metamizol (Methamizole) 阻止甲状腺产生甲状腺激素,是一种抗甲状腺药物。然而,Metamizol 具有肝毒性的副作用。
Metamizol (Methamizole) 阻止甲状腺产生甲状腺激素,是一种抗甲状腺药物。然而,Metamizol 具有肝毒性的副作用。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 mg | ¥ 10,600 | 5日内发货 | |
50 mg | ¥ 13,800 | 5日内发货 | |
100 mg | ¥ 17,500 | 5日内发货 |
产品描述 | Metamizol (Methamizole) blocks thyroid hormone production from the thyroid gland which is an anti-thyroid agent. However, Metamizol has hepatotoxicity as adverse effect [1]. |
体内活性 | Metamizo (Methamizole; 100 mg/kg; i.p.; once; male Swiss albino mice) causes hepatotoxicity as revealed by an increase in serum alanine aminotransferase (ALT) activity [1]. Metamizo (100 mg/kg; i.p.; once; male Swiss albino mice) causes a decrease in hepatic glutathione (GSH) contents [1]. Animal Model: Male Swiss albino mice (6 weeks old, 25-40 g) [1] Dosage: 100 mg/kg Administration: Intraperitoneal injection; once Result: Increased serum ALT level at 5 hours and the maximum serum ALT levels occurred at 5 hours. Animal Model: Male Swiss albino mice (6 weeks old, 25-40 g) [1] Dosage: 100 mg/kg Administration: Intraperitoneal injection; once Result: Induced reduction in hepatic glutathione (GSH) content in mice. |
分子量 | 311.36 |
分子式 | C13H17N3O4S |
CAS No. | 50567-35-6 |
存储 | Shipping with blue ice. |
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