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Targets Recommended: Others

814

抑制剂 & 化合物

140

天然产物

21

化合物库

531

重组蛋白

22

同位素标记化合物

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Cat. No. Product Name
DP1000 PPI计算机辅助药物设计库

230000 compounds
ChemDiv’s Protein-Protein Interaction Library contains 210,000 compounds. 陶术生物针对小规模PPI 药物筛选,基于结构多样性构建PPI 多样性子库,包含10397种小分子化合物。
L1310 细胞骨架化合物库

759 compounds
759 种细胞骨架相关的化合物,可以用于高通量和高内涵筛选;
L5500 毒性化合物库

262 compounds
262 个细胞毒性化合物的特有集合,可用于高通量、高内涵筛选。
L7300 钾通道分子库

152 compounds
152 种钾通道相关化合物的独特集合,可用于高通量筛选和高内涵筛选;
L3600 细胞因子抑制剂库

604 compounds
604 个与细胞因子紧密相关的化合物集合,是高通量、高内涵筛选的良好载体;
L2630 神经元分化化合物库

672 compounds
672 种与神经元分化相关的化合物,可以用于神经系统疾病药物研发
L4100 TGF-β/Smad靶点化合物库

184 compounds
184 个 TGF-β/Smad 靶点相关的小分子化合物的特有集合,用于高通量、高内涵筛选;
L5900 血脑屏障通透化合物库

509 compounds
509 个 CNS-Penetrant 生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L2500 人内源代谢化合物库

499 compounds
499 种内源性生物活性化合物的独特集合,用于高通量、高内涵筛选;
L7200 钙通道分子库

140 compounds
140 种钙通道相关化合物的独特集合,可用于高通量筛选和高内涵筛选;
L2600 神经信号分子库

2540 compounds
2540 种CNS 相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L2540 肠道微生物代谢化合物库

614 compounds
614 种肠道微生物代谢物的集合,可以用于高通量和高内涵筛选;
L5300 线粒体靶向库

812 compounds
812 种具有潜在或确定线粒体靶向活性的化合物,以促进针对线粒体的药物研究;
L2510 脂代谢化合物库

492 compounds
492 个脂代谢相关的化合物集合,可用于高通量和高内涵筛选;
L6120 黄酮类天然产物库

514 compounds
514 种黄酮类天然产物的独特集合,可用于高通量筛选和高内涵筛选;
L6000 高通量筛选天然产物库

4533 compounds
4533 种天然产物的独特集合,是药物开发、药理研究、干细胞分化、指纹图谱研究、质量研究等领域的有力工具,可用于HTS 和HCS;
L9420 外泌体相关化合物库

76 compounds
76 种外泌体相关的化合物,可以用于高通量和高内涵筛选;
L8500 HIF-1化合物库

1336 compounds
1336 个HIF-1相关小分子的独特集合,可用于缺血性疾病、癌症等相关领域的药物开发和药理研究;
L6750 活血化瘀中药单体库

580 compounds
580种来源于常见活血化瘀中药的单体化合物,是药物开发、药理研究等领域的有效工具。
L2550 谷氨酰胺代谢化合物库

565 compounds
565 种谷氨酰胺代谢相关的分子,可以用于高通量和高内涵筛选;
L6820 烟草单体化合物库

747 compounds
747种烟草单体化合物的独特集合,可用于高通量筛选和高内涵筛选

化合物库

PPI计算机辅助药物设计库
Cat.No: DP1000
Compounds: 230000
细胞骨架化合物库
Cat.No: L1310
Compounds: 759
毒性化合物库
Cat.No: L5500
Compounds: 262
钾通道分子库
Cat.No: L7300
Compounds: 152
细胞因子抑制剂库
Cat.No: L3600
Compounds: 604
神经元分化化合物库
Cat.No: L2630
Compounds: 672
TGF-β/Smad靶点化合物库
Cat.No: L4100
Compounds: 184
血脑屏障通透化合物库
Cat.No: L5900
Compounds: 509
人内源代谢化合物库
Cat.No: L2500
Compounds: 499
钙通道分子库
Cat.No: L7200
Compounds: 140
神经信号分子库
Cat.No: L2600
Compounds: 2540
肠道微生物代谢化合物库
Cat.No: L2540
Compounds: 614
线粒体靶向库
Cat.No: L5300
Compounds: 812
脂代谢化合物库
Cat.No: L2510
Compounds: 492
黄酮类天然产物库
Cat.No: L6120
Compounds: 514
高通量筛选天然产物库
Cat.No: L6000
Compounds: 4533
外泌体相关化合物库
Cat.No: L9420
Compounds: 76
HIF-1化合物库
Cat.No: L8500
Compounds: 1336
活血化瘀中药单体库
Cat.No: L6750
Compounds: 580
谷氨酰胺代谢化合物库
Cat.No: L2550
Compounds: 565
烟草单体化合物库
Cat.No: L6820
Compounds: 747
Cat. No. Product Name Target Signaling Pathways
T0940 Acesulfame Potassium

Others Others
Acesulfame potassium 是一种人造甜味剂,长期使用会影响认知功能,可能改变小鼠的神经代谢功能。
T12115 MSC2360844

PI3K PI3K/Akt/mTOR signaling
MSC2360844 是一种选择性的、具有口服活性的PI3Kδ抑制剂,其 IC50=145 nM。它对一组 278 种其他激酶显示出高度选择性。
T6116L Bleomycin hydrochloride

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Bleomycin hydrochloride is a potent antitumor antibiotic that functions as a DNA synthesis inhibitor and DNA damaging agent.
T35878 N-(3-Aminopropyl)cyclohexylamine

Others Others
N-(3-Aminopropyl)cyclohexylamine, a derivative of cyclohexylamine, functions as a selective and competitive inhibitor of spermine synthase, making it suitable for research on neurological diseases[1].
T2687 Omeprazole sulfide

Omeprazole metabolite Omeprazole sulfide,Ufiprazole,奥美拉唑硫醚

Proton pump; Drug Metabolite Membrane transporter/Ion channel; Metabolism
Omeprazole sulfide (Ufiprazole) 是 Omeprazole 的代谢物。
T38398 Abrucomstat

3-Nitroxypropanol,3-NOP

Others Others
Abrucomstat (3-NOP) 作为一种酶抑制剂,可减少瘤胃产甲烷作用。
T13118 Temiverine hydrochloride

Calcium Channel Membrane transporter/Ion channel; Metabolism
Temiverine hydrochloride 是一种潜在的钙离子通道拮抗剂,具有抗胆碱能作用,可抑制阿托品的部分功能。
T7574 Meptyldinocap

敌螨普,2,4-DNOPC

Antibacterial Microbiology/Virology
Meptyldinocap (2,4-DNOPC) 是一种新型白粉病杀菌剂。
T69923 Brigimadlin

BI 907828

Others Others
Brigimadlin (BI 907828) 是一种 E3 泛素蛋白连接酶 MDM-2抑制剂。Brigimadlin 可作为抗肿瘤剂。
T25372 EMD57033

EMD-57033,(+)-EMD 57033,EMD 57033

Calcium Channel; Carbonic Anhydrase Membrane transporter/Ion channel; Metabolism
EMD57033是一种心脏肌钙蛋白C(cTnC)激活剂,是一种显性的Ca2+增敏剂。EMD57033通过与心脏/慢速骨骼肌钙蛋白C 异构体结合从而发挥促进心脏收缩的功能。
T7137 I-191

Protease-activated Receptor GPCR/G Protein
I-191 是选择性有效的蛋白酶激活受体 2 拮抗剂。
T4446 Tebufenpyrad

Pyranica,吡螨胺,MK239,Comanche

Mitochondrial Metabolism Metabolism
Tebufenpyrad (Comanche) 是一种重要的农业化学杀螨剂,其作用类似于已知的线粒体毒物 rotenone。
TP1035 Cyclic somatostatin

SRIF-14,合成生长抑素,环状生长激素抑制素,Somatostatin-14

Others Others
Cyclic somatostatin (SRIF-14) 是生长激素释放抑制因子,可用于研究胃十二指肠溃疡出血。
T9961 L82-G17

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
L82-G17 是人体细胞中的一种非竞争性 LigI 选择性抑制剂,可用作 LigI 的催化活性和细胞功能的探针。
T15711 Larazotide acetate

Gap Junction Protein Cytoskeletal Signaling
Larazotide acetate 是合成肽,它起到紧密连接调节器的作用,并将泄漏连接反转到它们的常闭状态。
TP1035L Cyclic somatostatin Acetate

Somatostatin (sheep), monoacetate (salt),Cyclic somatostatin Acetate(38916-34-6 free base),Somatostatin-14,SRIF-14,monoacetate (salt)

Others Others
Cyclic somatostatin Acetate(38916-34-6(free base)) (Somatostatin-14) 是一种环状十四肽,可调节许多内分泌和神经系统功能。
T12015 Methyl homoveratrate

Others Others
Methyl homoveratrate 是血浆、尿液和粪便提取物中 McN5691 的代谢物,是电压依赖性钙通道阻滞剂。
T5015 Gonadorelin Acetate (33515-09-2 free base)

醋酸戈那瑞林,Luteinizing Hormone Releasing Hormone (LH-RH),Luteinizing Hormone Releasing Hormone (LH-RH), human,Gonadorelin Acetate

Reductase Endocrinology/Hormones; Metabolism
Gonadorelin Acetate (33515-09-2 free base) (Luteinizing Hormone Releasing Hormone (LH-RH)) 是下丘脑神经肽,在控制生殖功能中起关键作用。
T23008L MMPIP hydrochloride

MMPIP hydrochloride (479077-02-6 Free base)

GluR Neuroscience
MMPIP hydrochloride 是变构 mGluR7 的选择性拮抗剂。 MMPIP hydrochloride 可用于研究 mGluR7 对中枢神经系统功能的作用。
T19561 Simetryn

Others Others
Simetryn 是一种稻田除草剂,可作为一种化学应激源,延缓蝌蚪的生长和发育,而不会破坏甲状腺功能,即使在 96 小时 LC50 值的 1/100 时也是如此。
T11077 Dopamine D2 receptor antagonist-1

Others Others
Dopamine D2 receptor antagonist-1,一种对多巴胺D2受体(D2R)表现出亚毫摩尔级别亲和力的负变构调节剂(NAM)。
TP1648L [Gln8]-C517 (LH-RH), chicken acetate

[Gln8]-C517 (LH-RH), chicken acetate(47922-48-5 free base)

Others Others
[Gln8]-C517 (LH-RH), chicken acetate(47922-48-5 free base) 是一种鸟类下丘脑肽,可刺激垂体前叶释放促性腺激素,从而调节生殖功能。
T50088 N-phenylthiophene-2-carboximidamide

Others Others
N-phenylthiophene-2-carboximidamide 是一种噻吩衍生物,可以作为蛋白酪氨酸激酶(PTKs)的抑制剂和 G 蛋白偶联受体(GPCR)的配体发挥作用。
T0472 Venlafaxine hydrochloride

Venlafaxine HCl,盐酸文拉法辛,Wy 45030 hydrochloride

5-HT Receptor; Serotonin Transporter GPCR/G Protein; Neuroscience
Venlafaxine hydrochloride (Wy 45030 hydrochloride) 是一种口服有效的 5-羟色胺 (5-HT)/去甲肾上腺素 (NE) 重摄取的双重抑制剂,具有抗抑郁活性。
T2102 FH1

BRD-K4477,NSC 12407

Others Others
FH1 (NSC-12407) 可提高肝细胞功能,促进诱导多能干 (iPS) 衍生的肝细胞向更成熟的表型分化,并促使分化良好的肝细胞样细胞 (iHeps) 培养物的成熟。
T39578 TPh A

Triphenyl Compound A

Others Others
TPh A (Triphenyl Compound A) 是核蛋白 pirin 抑制剂( Ki:0.6 uM),是一种可作为生物探针的蛋白质,可调节 pirin 的相关功能。
T17921 (S,R,S)-AHPC-PEG4-N3

VH032-PEG4-N3,VHL Ligand-Linker Conjugates 5,E3 ligase Ligand-Linker Conjugates 4

Others; PROTAC Linker Others; PROTAC
(S,R,S)-AHPC-PEG4-N3 (VHL Ligand-Linker Conjugates 5) is a synthesized conjugate that functions as a ligand-linker in E3 ligase-based systems. It is composed of the (S,R,S)-AHPC VHL ligand and a 4-unit PEG linker, both commonly employed in PROTAC technology.
T12022 Metronidazole Benzoate

Benzoyl metronidazole

Antibacterial Microbiology/Virology
Metronidazole Benzoate (Benzoyl metronidazole) 是甲硝唑和苯甲酸衍生物,具有抗菌,抗寄生虫,抗滴虫等作用,常用于治疗由厌氧菌引起的感染。
T0112 Diltiazem hydrochloride

CRD-401,盐酸地尔硫卓,RG 83606 HCl,Diltiazem HCl

Calcium Channel Membrane transporter/Ion channel; Metabolism
Diltiazem hydrochloride (RG 83606 HCl) 是一种苯并硫氮卓类钙通道阻滞剂,由于其拮抗钙离子对膜功能的作用而具有血管舒张作用。
T16873 SERCA2a activator 1

Calcium Channel Membrane transporter/Ion channel; Metabolism
SERCA2a activator 1 是一种肌肉/内质网 Ca2+ 依赖性 ATPase 2a 激活剂。 SERCA2a activator 1 降低受磷蛋白抑制并增强心脏的收缩和舒张功能。
T13059 T16Ainh-A01

Chloride channel Membrane transporter/Ion channel
T16Ainh-A01 是氨基苯基噻唑,是有效的跨膜蛋白 16A 的抑制剂,抑制 TMEM16A 介导的氯离子电流,IC50约为1 µM。TMEM16A (ANO1)起钙激活氯离子通道(CaCC)的作用。
T1657 Varenicline Tartrate

Champix tartrate,酒石酸伐尼克兰,Chantix tartrate,CP 526555-18,酒石酸伐仑克林

AChR Neuroscience
Varenicline Tartrate (CP 526555-18) 是α4β2 烟碱乙酰胆碱受体的部分激动剂,EC50为 2.3 μM。它是 α3β4 和 α7 乙酰胆碱受体完全激动剂,EC50值分别为 55 和 18 μM,用于戒烟方面的研究。
T10032 COX-2-IN-2

COX Immunology/Inflammation; Neuroscience
COX-2-IN-2 是选择性的,诱导型的 COX2 抑制剂,IC50 值为0.24 μM。COX-2-IN-2 是具有抗炎和止痛活性的抗炎物。
T61214 EWP 815

Phosphatase; Hydroxylase Metabolism
EWP 815是一种二硫仑类似物,是 Ins(1,4) P 2磷酸酶、Ins(1,4,5) P 3 5-磷酸酶和多巴胺β-羟化酶活性的强效抑制剂[1] [2]。
T9782 Cytochrome C

Others Others
Cytochrome C 是一种属于 c 型细胞色素家族 1 类的蛋白质,根据其细胞定位和其工作条件发挥不同的功能。
T0154 Nebivolol hydrochloride

R 065824 hydrochloride,盐酸奈必洛尔,Nebivolol HCl,R-65824

Apoptosis; Adrenergic Receptor Apoptosis; GPCR/G Protein; Neuroscience
Nebivolol hydrochloride (R 065824 hydrochloride) 是一种β1-肾上腺素受体选择性抑制剂,IC50为0.8 nM。
T3553 Y16

Rho; Ras Cell Cycle/Checkpoint; GPCR/G Protein; MAPK
Y16 是一种 G 蛋白偶联的 Rho GEFs 抑制剂,与 Rhosin/G04 协同作用,抑制 LARG-RhoA 相互作用、RhoA 激活和 RhoA 介导的信号传导功能。它是 LARG 的特异性抑制剂,Kd 值为 76 nM。
FL0195 N-Boc-4-hydroxy-L-proline methyl ester

Others; ADC Linker Antibody-drug Conjugate/ADC Related; Others
N-Boc-cis-4-hydroxy-L-proline methyl ester为不可降解(non-cleavable)的ADC linker,用于抗体药物偶联体(ADCs)合成。该化合物同时作为基于烷基链(alkyl chain)的PROTAC linker,适用于PROTAC合成。
T14345 Atropine methyl bromide

甲溴阿托品,Methylatropine bromide

AChR Neuroscience
Atropine methyl bromide (Methylatropine bromide) is a quaternary ammonium salt of atropine, characterized as a muscarinic receptor (mAChR) antagonist. It functions as a mydriatic to dilate the pupil during ophthalmic examination. Compared to atropine, it demonstrates reduced penetration into the central nervous system[1][2]. Its high polarity makes it particularly effective in relieving pyloric spasm in infants.
T23840 BUR1

BMP upregulator-1,1-{1-苯基-1H-吡唑并[3,4-D]嘧啶-4-基}哌啶,BMP upregulator 1,BUR 1,BUR-1

CDK Cell Cycle/Checkpoint
BUR1 是一种酿酒酵母细胞周期蛋白依赖性激酶 (CDK),与在转录延伸中起作用的哺乳动物 Cdk9 同源。
T36572 N6-Methyladenine

6-(甲氨基)嘌呤,N6-Methyladenine,6-(Methylamino)Purine

Nucleoside Antimetabolite/Analog Cell Cycle/Checkpoint; DNA Damage/DNA Repair
N6-Methyladenine (6-(Methylamino)Purine) 是一种修饰的嘌呤,常见于原核生物、原生生物和植物的基因组中。 N6-Methyladenine 影响多种 DNA 功能,包括复制、修复和表达。
T78170 Kras4B G12D-IN-1

Ras GPCR/G Protein; MAPK
Kras4B G12D-IN-1为Kras4B G12D的抑制剂,表现出抗癌活性。在降低Kras4B G12D表达的小鼠胚胎成纤维细胞(MEF)中减少Kras蛋白水平。
T9329 BRD0639

Histone Methyltransferase Chromatin/Epigenetic
BRD0639 是首创的PRMT5-substrate adaptor interaction 的抑制剂。BRD0639 是一种 PRMT5 结合基序 (PBM) 竞争性抑制剂,可以支持 PBM 依赖的 PRMT5 活性的研究。
T8557 N-terminally acetylated Leu-enkephalin

Opioid Receptor Endocrinology/Hormones; GPCR/G Protein; Neuroscience
N-terminally acetylated Leu-enkephalin 是一种五氨基酸内源性肽,可作为阿片受体激动剂。N-末端乙酰化 Leu-脑啡肽是 Leu-脑啡肽的 N-末端乙酰化形式。
T1060 Flumequine

Flumigal,氟甲喹,R-802

Topoisomerase; Antibacterial; Antibiotic DNA Damage/DNA Repair; Microbiology/Virology
Flumequine (R-802) 是一种喹诺酮类抗生素,对革兰氏阳性菌和革兰氏阴性菌均有效。它是拓扑异构酶 II 抑制剂, 抑制细胞分裂,IC50值为 15 μM (3.92 μg/mL)。
T6246 Cobicistat

Tybost,GS-9350,考西司他

P450; HIV Protease Metabolism; Microbiology/Virology; Proteases/Proteasome
Cobicistat (GS-9350) 是一种细胞色素酶P450 3A 的选择性抑制剂,IC50值为30-285 nM。它是一种药代动力学增强剂,可增强抗 HIV 药物的吸收。
T0059 Diphenylpyraline hydrochloride

盐酸双苯比拉林,4-Diphenylmethoxy-1-methylpiperidine hydrochloride

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Diphenylpyraline hydrochloride (4-Diphenylmethoxy-1-methylpiperidine hydrochloride) 是一种组胺 H1 受体的拮抗剂,抑制多巴胺的吸收。它是可口服的抗组胺试剂,具有抗胆碱和抗过敏作用,可用于缓解过敏性疾病,如鼻炎、花粉热和瘙痒性皮肤疾病等。
T9807 CPDS

Others Others
CPDS 是一种非渗透性硫醇剂,可影响多种线粒体功能。在大鼠肝线粒体中,它仅抑制 Pi/OH- 载体。它和丙二酸正丁酯都是完全抑制 Pi 进入所必需的。
TP1083L Neuromedin U (rat) acetate

Others Others
Neuromedin U (rat) acetate 是一种 23 个氨基酸的脑肠肽。 Neuromedin U (NMU) 通过其在中枢神经系统中的同源受体 NMUR2 调节几种重要的生理功能,包括能量平衡、压力反应和伤害感受。
T60325 Viloxazine

Emovit,Viloxazin

5-HT Receptor; Norepinephrine GPCR/G Protein; Neuroscience
Viloxazine (Viloxazin) (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and exhibits potent agonistic activity towards 5-HT 2C receptors while acting as an antagonist for 5-HT 2B receptors, with respective potency values of EC 50 = 32 μM and IC 50 = 27 μM. Its primary mechanism of action involves the modulation of serotonergic and noradrenergic pathways. Viloxazine is commonly employed in depression research [1] [2].

化合物

Acesulfame Potassium
Cat.No: T0940
Synonym:
Target: Others
MSC2360844
Cat.No: T12115
Synonym:
Target: PI3K
Bleomycin hydrochloride
Cat.No: T6116L
Synonym:
Target: DNA/RNA Synthesis
N-(3-Aminopropyl)cyclohexylamine
Cat.No: T35878
Synonym:
Target: Others
Omeprazole sulfide
Cat.No: T2687
Synonym: Omeprazole metabolite Omeprazole sulfide,Ufiprazole,奥美拉唑硫醚
Target: Proton pump, Drug Metabolite
Abrucomstat
Cat.No: T38398
Synonym: 3-Nitroxypropanol,3-NOP
Target: Others
Temiverine hydrochloride
Cat.No: T13118
Synonym:
Target: Calcium Channel
Meptyldinocap
Cat.No: T7574
Synonym: 敌螨普,2,4-DNOPC
Target: Antibacterial
Brigimadlin
Cat.No: T69923
Synonym: BI 907828
Target: Others
EMD57033
Cat.No: T25372
Synonym: EMD-57033,(+)-EMD 57033,EMD 57033
Target: Calcium Channel, Carbonic Anhydrase
I-191
Cat.No: T7137
Synonym:
Target: Protease-activated Receptor
Tebufenpyrad
Cat.No: T4446
Synonym: Pyranica,吡螨胺,MK239,Comanche
Target: Mitochondrial Metabolism
Cyclic somatostatin
Cat.No: TP1035
Synonym: SRIF-14,合成生长抑素,环状生长激素抑制素,Somatostatin-14
Target: Others
L82-G17
Cat.No: T9961
Synonym:
Target: DNA/RNA Synthesis
Larazotide acetate
Cat.No: T15711
Synonym:
Target: Gap Junction Protein
Cyclic somatostatin Acetate
Cat.No: TP1035L
Synonym: Somatostatin (sheep), monoacetate (salt),Cyclic somatostatin Acetate(38916-34-6 free base),Somatostatin-14,SRIF-14,monoacetate (salt)
Target: Others
Methyl homoveratrate
Cat.No: T12015
Synonym:
Target: Others
Gonadorelin Acetate (33515-09-2 free base)
Cat.No: T5015
Synonym: 醋酸戈那瑞林,Luteinizing Hormone Releasing Hormone (LH-RH),Luteinizing Hormone Releasing Hormone (LH-RH), human,Gonadorelin Acetate
Target: Reductase
MMPIP hydrochloride
Cat.No: T23008L
Synonym: MMPIP hydrochloride (479077-02-6 Free base)
Target: GluR
Simetryn
Cat.No: T19561
Synonym:
Target: Others
Dopamine D2 receptor antagonist-1
Cat.No: T11077
Synonym:
Target: Others
[Gln8]-C517 (LH-RH), chicken acetate
Cat.No: TP1648L
Synonym: [Gln8]-C517 (LH-RH), chicken acetate(47922-48-5 free base)
Target: Others
N-phenylthiophene-2-carboximidamide
Cat.No: T50088
Synonym:
Target: Others
Venlafaxine hydrochloride
Cat.No: T0472
Synonym: Venlafaxine HCl,盐酸文拉法辛,Wy 45030 hydrochloride
Target: 5-HT Receptor, Serotonin Transporter
FH1
Cat.No: T2102
Synonym: BRD-K4477,NSC 12407
Target: Others
TPh A
Cat.No: T39578
Synonym: Triphenyl Compound A
Target: Others
(S,R,S)-AHPC-PEG4-N3
Cat.No: T17921
Synonym: VH032-PEG4-N3,VHL Ligand-Linker Conjugates 5,E3 ligase Ligand-Linker Conjugates 4
Target: Others, PROTAC Linker
Metronidazole Benzoate
Cat.No: T12022
Synonym: Benzoyl metronidazole
Target: Antibacterial
Diltiazem hydrochloride
Cat.No: T0112
Synonym: CRD-401,盐酸地尔硫卓,RG 83606 HCl,Diltiazem HCl
Target: Calcium Channel
SERCA2a activator 1
Cat.No: T16873
Synonym:
Target: Calcium Channel
T16Ainh-A01
Cat.No: T13059
Synonym:
Target: Chloride channel
Varenicline Tartrate
Cat.No: T1657
Synonym: Champix tartrate,酒石酸伐尼克兰,Chantix tartrate,CP 526555-18,酒石酸伐仑克林
Target: AChR
COX-2-IN-2
Cat.No: T10032
Synonym:
Target: COX
EWP 815
Cat.No: T61214
Synonym:
Target: Phosphatase, Hydroxylase
Cytochrome C
Cat.No: T9782
Synonym:
Target: Others
Nebivolol hydrochloride
Cat.No: T0154
Synonym: R 065824 hydrochloride,盐酸奈必洛尔,Nebivolol HCl,R-65824
Target: Apoptosis, Adrenergic Receptor
Y16
Cat.No: T3553
Synonym:
Target: Rho, Ras
N-Boc-4-hydroxy-L-proline methyl ester
Cat.No: FL0195
Synonym:
Target: Others, ADC Linker
Atropine methyl bromide
Cat.No: T14345
Synonym: 甲溴阿托品,Methylatropine bromide
Target: AChR
BUR1
Cat.No: T23840
Synonym: BMP upregulator-1,1-{1-苯基-1H-吡唑并[3,4-D]嘧啶-4-基}哌啶,BMP upregulator 1,BUR 1,BUR-1
Target: CDK
N6-Methyladenine
Cat.No: T36572
Synonym: 6-(甲氨基)嘌呤,N6-Methyladenine,6-(Methylamino)Purine
Target: Nucleoside Antimetabolite/Analog
Kras4B G12D-IN-1
Cat.No: T78170
Synonym:
Target: Ras
BRD0639
Cat.No: T9329
Synonym:
Target: Histone Methyltransferase
N-terminally acetylated Leu-enkephalin
Cat.No: T8557
Synonym:
Target: Opioid Receptor
Flumequine
Cat.No: T1060
Synonym: Flumigal,氟甲喹,R-802
Target: Topoisomerase, Antibacterial, Antibiotic
Cobicistat
Cat.No: T6246
Synonym: Tybost,GS-9350,考西司他
Target: P450, HIV Protease
Diphenylpyraline hydrochloride
Cat.No: T0059
Synonym: 盐酸双苯比拉林,4-Diphenylmethoxy-1-methylpiperidine hydrochloride
Target: Histamine Receptor
CPDS
Cat.No: T9807
Synonym:
Target: Others
Neuromedin U (rat) acetate
Cat.No: TP1083L
Synonym:
Target: Others
Viloxazine
Cat.No: T60325
Synonym: Emovit,Viloxazin
Target: 5-HT Receptor, Norepinephrine
Cat. No. Product Name Target Signaling Pathways
T0443 Salicin

Salicoside,水杨甙,Salicine,水杨苷,D-(−)-Salicin

COX Immunology/Inflammation; Neuroscience
Salicin (Salicine) 是天然的COX 抑制剂。
T20476 Lauroyl lysine

月桂酰赖氨酸,N6-Lauroyl-L-lysine

Others Others
Lauroyl lysine (N6-Lauroyl-L-lysine) 在个人护理产品中用作皮肤和头发调理剂以及表面活性剂-清洁剂。
TN2010 Ombuin

商陆黄素,商陆素

Antibacterial Microbiology/Virology
Ombuin 是一种从花椒中分离出的广谱抗菌剂,MIC 为 125 至 500 μg/mL。
TQ0234 Epoxymicheliolide

1β,10β-Epoxymicheliolide,环氧木香内酯

Others Others
Epoxymicheliolide 是木香内酯衍生物的一种,抑制破骨细胞生成。
T4759 Urocanic acid

4-Imidazoleacrylic acid,尿刊酸

Others; Endogenous Metabolite Metabolism; Others
Urocanic acid(4-Imidazoleacrylic acid)存在于表皮中,是哺乳动物皮肤中紫外线(UV)辐射的主要吸收物。
T5281 Skatole

粪臭素,Scatole,3-Methylindole,3-​Methylindole,3-甲基吲哚,3-Methyl-1H-indole,beta-Methylindole

AhR; p38 MAPK; Aryl Hydrocarbon Receptor; Endogenous Metabolite; Antibacterial; Autophagy; Antifungal Autophagy; Immunology/Inflammation; MAPK; Metabolism; Microbiology/Virology
Skatole (3-Methyl-1H-indole) 是由肠道菌群产生的,通过激活芳基烃受体和 p38调节肠上皮细胞功能。
TN2346 Mogrol

ERK; AMPK; STAT Chromatin/Epigenetic; JAK/STAT signaling; MAPK; PI3K/Akt/mTOR signaling; Stem Cells
Mogrol 是罗汉果中的一种天然产物,通过抑制 ERK1/2 和 STAT3 通路,减少 CREB 激活和激活 AMPK 信号传导发挥作用。
T8030 Ethyl pyruvate

Apoptosis; Antioxidant Apoptosis; oxidation-reduction
Ethyl pyruvate 是一种内源性代谢物丙酮酸的衍生物,是一种抗炎剂。
TQ0158 Azaserine

CI-337,偶氮丝胺酸,P-165,氮杂丝氨酸,O-Diazoacetyl-L-serine

Others; Antibiotic Microbiology/Virology; Others
Azaserine (CI-337) 是一种从链霉菌属中分离出来的肿瘤抑制抗生素,可作为谷氨酰胺氨基转移酶的抑制剂。
T5542 Tiglic acid

惕格酸,Sabadillic acid,Tiglinic acid,巴豆酸,Cevadic acid

Endogenous Metabolite; HSV Metabolism; Microbiology/Virology
Tiglic acid 是一种存在于巴豆油和其他几种天然产物中的单羧酸不饱和有机酸。它具有植物代谢物的作用。
T2140 Parthenolide

(-)-Parthenolide,小白菊内酯

Apoptosis; Mitophagy; NF-κB; HDAC; Autophagy Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; NF-κB
Parthenolide ((-)-Parthenolide) 是一种从药草短舌匹菊中发现的倍半萜内酯。 它抑制NF-κB 活化,有抗炎活性。它还可抑制HDAC1蛋白,但不影响其他I/II 类HDAC。
TQ0240 6"-O-Apiosyl-5-O-Methylvisammioside

Others Others
6”-O-Apiosyl-5-O-Methylvisammioside 是中药颈复康的成分之一,颈复康具有活血通络,散风止痛的作用。
T2956 Cedryl acetate

乙酸柏木酯,Cedrol acetate,Cedranyl acetate

Antifungal Microbiology/Virology
Cedryl acetate (Cedranyl acetate) 是一种三环倍半萜烯,分离自草莓番石榴植物,能够表现出 α-葡萄糖苷酶的抑制活性。
T2810 (20S)-Protopanaxatriol

原人参三醇,20(S)-APPT,20 (S)-原人参三醇,g-PPT

Apoptosis; Estrogen Receptor/ERR; Glucocorticoid Receptor; Estrogen/progestogen Receptor; Liver X Receptor Apoptosis; Endocrinology/Hormones; Metabolism
(20S)-Protopanaxatriol (g-PPT) 是人参皂苷的代谢物,通过糖皮质激素受体和雌激素受体起作用,同时为LXRα的抑制剂,具有广泛的抗癌活性。
T73844 Nortriptyline

Others Others
Nortriptyline (Desmethylamitriptyline) 是三环类抗抑郁药,是 Amitriptyline 的主要活性代谢产物,用于缓解抑郁症症状。Nortriptyline 是有效自噬 (autophagy) 抑制剂。
T2O2774 L-Asparagine

alpha-aminosuccinamic acid,L-天门冬氨酸,(-)-Asparagine,Asparamide,2-Aminosuccinamic acid,Asn,Altheine

Endogenous Metabolite Metabolism
L-Asparagine (Asparamide) 是一种非必需氨基酸,可以参与神经和脑组织细胞功能的代谢控制。
TN1445 Bisabolangelone

p38 MAPK; MAPK MAPK
Bisabolangelone 是从没药中分离出来的一种倍半萜衍生物,具有抗炎作用。它通过阻断巨噬细胞内的NF-kappaB 和MAPK 通路抑制脂多糖刺激的炎症,具有抗溃疡作用。
T2745 18α-Glycyrrhetinic acid

18-α-甘草次酸,甘草次酸,Enoxolone,Glycyrrhetinic acid

Apoptosis; NF-κB; Proteasome Apoptosis; NF-κB; Proteases/Proteasome; Ubiquitination
18α-Glycyrrhetinic acid (Enoxolone) 是 NF-kB 的抑制剂和蛋白酶体的激活剂,在多细胞生物中起到促进长寿和抗聚集因子的作用。它诱导细胞凋亡。
T39359 γ-Glu-Gly

gamma-Glutamylglycine

Amino Acids and Derivatives Metabolism
γ-Glu-Gly(gamma-Glutamylglycine),一种γ-谷氨酰基二肽,是具有与GABA(γ-氨基丁酸)相似结构的人体脂质代谢产物,可作为兴奋性氨基酸的拮抗剂。
T5770 Alisol B

RANKL/RANK NF-κB
Alisol B 是一种具有用于骨科疾病研究潜力的化合物,通过分化破骨细胞发挥其功能。
T7094 Levomefolic Acid

L-5-甲基四氢叶酸,5-MTHF,5-甲基四氢叶酸

Reactive Oxygen Species; Endogenous Metabolite Immunology/Inflammation; Metabolism; NF-κB
Levomefolic Acid (5-MTHF) 是一种具有口服活性、可穿过血脑屏障的天然活性叶酸,是广泛使用的叶酸食品补充剂。
T5067 Flavin adenine dinucleotide disodium salt

Flavin Adenine Dinucleotide Disodium,黄素腺嘌呤二核苷酸二钠,FAD sodium salt,FAD-Na2

Others; Endogenous Metabolite Metabolism; Others
Flavin adenine dinucleotide disodium salt (FAD sodium salt) 是一种辅酶,作用是促进细胞氧化还原反应中黄素酶的电子转移。
T3900 Emodin-8-glucoside

大黄素-8-β-D-吡喃葡萄糖苷,Emodin glucoside B,Anthraglycoside B

Others Others
Emodin-8-glucoside (Anthraglycoside B) 是从芦荟中分离出的蒽醌衍生物,与 DNA 的小沟结合。它具有保护缺血和再灌注引起的局灶性脑损伤的作用。它直接刺激成骨细胞的细胞增殖和分化。
T2918 Cholesteryl Acetate

Cholesterin acetate,胆甾醇乙酸酯,Cholesterol acetate,Acebrochol

Others Others
Cholesteryl Acetate 是胆固醇的羟基被乙酸形式酰化而得到的胆固醇酯。它具有作为人体代谢物的作用。它是一种胆固醇酯和一种乙酸酯。
TN1420 Bacopaside I

Others Others
Bacopaside I 是一种皂苷,分离自 Bacopa monniera 中,具有抗氧化活性和清除自由基的功能,有抗抑郁作用。
T6220 Nicotinamide riboside chloride

烟酰胺核糖氯酸盐,烟酰胺核苷

Sirtuin; Endogenous Metabolite Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism
Nicotinamide riboside Chloride 是维生素 B3 的来源,可以增强氧化代谢并防止高脂肪饮食诱导的代谢异常。它是具有口服活性的 NAD+的前体,增加 NAD+水平并激活SIRT1和SIRT3,可用于研究阿尔茨海默氏病的认知退化。
TN6745 PALATINOSE

TNP-470,帕拉金糖水合物,Isomaltulose

Others Others
PALATINOSE (TNP-470) 是一种天然存在的二糖,由α-1,6-连接的葡萄糖和果糖组成。PALATINOSE 对肝脏代谢功能具有有益的影响,因此可能是蔗糖甜味剂的良好替代品。
T4915 β-Glycerophosphate disodium salt hydrate

Phosphatase; Endogenous Metabolite Metabolism
β-Glycerophosphate disodium salt hydrate 是一种磷酸酶抑制剂,是内源性代谢产物的一种。
T0928 L-Ascorbic acid

维生素C,Vitamin C,Ascorbic acid,L(+)-Ascorbic acid,抗坏血酸,L-Ascorbate

Apoptosis; Calcium Channel; Reactive Oxygen Species; Endogenous Metabolite Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; NF-κB
L-Ascorbic acid (Vitamin C) 属于天然产物,是一种强效的还原剂和抗氧化剂。L-Ascorbic acid 具有抗细菌感染、解毒反应和胶原蛋白形成的作用。L-Ascorbic acid 被用于治疗坏血病。
T10024 1-Octanol

Octanol,正辛醇

Calcium Channel; Endogenous Metabolite Membrane transporter/Ion channel; Metabolism
1-Octanol (Octanol) 是一种饱和脂肪醇,是一种 T 型钙通道抑制剂,对天然 T 电流的IC50为 4 μM。它是一种具有类似柴油特性的极具吸引力的生物燃料。
TJO2742 DL-Methionine

蛋氨酸,methionine,DL-蛋氨酸,Acimetion,Racemethionine

Parasite Microbiology/Virology
DL-Methionine (Acimetion) 存在于肉类、鱼类和奶制品中,是可用于动物的天然饲料,还可杀死马铃薯上的金线虫。它是一种含有硫的必需氨基酸,具有氧化应激防御作用。
TN2272 Tigloylgomisin H

Nrf2 Immunology/Inflammation
Tigloylgomisin H 是分离自S. chinensis 果实中的木酚素。Tigloylgomisin H 能诱导小鼠肝癌细胞 Hepa1c1c7 中醌还原酶活性。Tigloylgomisin H 是单功能诱导剂,通过 Nrf2-ARE 途径特异性上调 II 期解毒酶 NQO1。Tigloylgomisin H 是潜在的肝癌预防剂。
T0375 Atropine

DL-Hyoscyamine,阿托品,Tropine tropate,颠茄碱

Endogenous Metabolite; AChR Metabolism; Neuroscience
Atropine (DL-Hyoscyamine) 是竞争性的毒蕈碱乙酰胆碱受体拮抗剂,有抗近视效果。它是一种从颠茄植物中分离出来的天然生物碱,可阻断乙酰胆碱对心率和收缩力的抑制作用。
T5S1895 Norisoboldine

Laurelliptine,去甲异波尔定,(+)-Laurelliptine

MAPK; Adenosine Receptor GPCR/G Protein; MAPK; Neuroscience
Norisoboldine ((+)-Laurelliptine) 是一种可口服的芳基烃受体激动剂,是乌药中主要的异喹啉类生物碱,可用于类风湿性关节炎和溃疡性结肠炎的研究。
T1407 (-)-Menthol

L-Menthol,Levomenthol,(-)-薄荷醇,薄荷冰,Menthomenthol,Menthacamphor

Opioid Receptor; Endogenous Metabolite; TRP/TRPV Channel Endocrinology/Hormones; GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Neuroscience
(-)-Menthol (Levomenthol) 分离自薄荷油,L-Menthol 是瞬时受体电位 M8 (TRPM8)的激活剂,TRPM8 是 Ca2+-可渗透的非选择性阳离子通道,并增加 [Ca2+]i。L-Menthol 具有抗肿瘤活性。
T3228 Fosfructose

D-fructose-1,6-diphosphate,Betulanonaprenol,4937-84-2,Diphosphofructose,二磷酸果糖,Fructose 1,6-diphosphate,D-fructofuranose 1,6-bisphosphate,Esafosfan

Others; Endogenous Metabolite Metabolism; Others
D-fructose-1,6-diphosphate 是一种细胞保护性的天然糖磷酸盐,Fosfructose 通过刺激无氧糖酵解起作用,其在缺血条件下产生三磷酸腺苷,有潜力用于心血管缺血,镰状细胞性贫血和哮喘的研究。
T19529 Proteinase

Others Others
Proteinase 是一种催化蛋白质分解的酶。它们通过水解作用来裂解蛋白质内的肽键,将蛋白质分解成更小的多肽或单个氨基酸。Proteinase 参与许多生物功能,包括消化进食的蛋白质、旧蛋白质的分解,以及细胞信号传递。它们同时促进新的蛋白质产物的形成
T4973 Paraxanthine

1,7-二甲基黄嘌呤,1,7-DIMETHYLXANTHINE

Endogenous Metabolite Metabolism
Paraxanthine (1,7-dimethylxanthine) 是一种 caffeine 的代谢物,能够刺激Ryanodine 受体通道来抑制多巴胺能细胞的死亡。
T5S0167 Atractylenolide I

白术内酯 I,白术内酯I;苍术内酯I

IL Receptor; TNF; TLR; JAK; STAT Angiogenesis; Apoptosis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Stem Cells
Atractylenolide I 是从白术根中得到的一种倍半萜烯,具有神经保护、抗过敏、抗炎和抗癌等多种生物活性。它是一种TLR4拮抗剂,在 A375 细胞中,能够降低JAK2和STAT3的磷酸化水平。
T5530 Mithramycin A

Plicamycin

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Mithramycin A (Plicamycin) 是一种dna 结合的抗肿瘤抗生素,选择性特异性蛋白1 (Sp1)抑制剂,通过降低Sp1蛋白抑制多种肿瘤的生长。特异性蛋白1 (Sp1)是一种锌指转录因子,调节多种细胞功能,促进肿瘤进展。
T16340 Nosiheptide

RP 9671,Multhiomycin,那西肽

Antibacterial; Antibiotic Microbiology/Virology
Nosiheptide (Multhiomycin) 是一种由 Streptomyces actuosus 生产的硫肽类抗生素,已被广泛用作动物生长的饲料添加剂。它抑制细菌蛋白质合成,并在特征性大环核心上带有独特的吲哚侧环系统和区域特异性羟基。
T3O2749 L-Leucine

(S)-Leucine,Leu,L-亮氨酸,亮氨酸

mTOR PI3K/Akt/mTOR signaling
L-Leucine ((S)-Leucine) 是必需的支链氨基酸,能够激活 mTOR 信号通路。
T2909 Fraxetin

7,8-dihydroxy-6-methoxy coumarin,秦皮素,弗拉西汀

Apoptosis; Others Apoptosis; Others
Fraxetin (7,8-dihydroxy-6-methoxy coumarin) 是从秦皮中分离出来的一种天然产物,可诱导细胞凋亡,具有抗肿瘤、抗氧化作用和抗炎作用。
T1040 Vitamin B12

Cyanocobalamin,Cobalamin,维生素B12

Endogenous Metabolite Metabolism
Vitamin B12 (Cobalamin) 是一种维生素,在维持血流形成和脑、神经系统正常功能等方面发挥关键作用。
T6480 D-Pantothenic acid

vitamin B5,pantothenate,D-泛酸

Others Others
D-Pantothenic acid (vitamin B5) 是必需的微量营养素,是辅酶 A 的前体,在很多生物过程中发挥关键作用,如调节碳水化合物,脂质,蛋白和核酸代谢。
T2A2532 L-Histidine

Glyoxaline-5-alanine,L-(-)-Histidine,L-组氨酸,histidine,组氨酸,L-Hisidine

Mitochondrial Metabolism; Endogenous Metabolite Metabolism
L-Histidine (L-(-)-Histidine) 是人类生长和组织修复所需的一种半必需氨基酸(儿童应从食物中获得)。 L-Histidine 是线粒体谷氨酰胺转运的抑制剂。
T4429 Rauwolscine hydrochloride

Corynanthidine hydrochloride,盐酸育亨宾碱,萝芙素盐酸盐,α-Yohimbine hydrochloride,Isoyohimbine hydrochloride

Adrenergic Receptor GPCR/G Protein; Neuroscience
Rauwolscine hydrochloride (Isoyohimbine hydrochloride) 是一种高选择性的 α2 adrenergic 受体拮抗剂,Ki=12 nM。
T2S2173 (E)-Naringenin chalcone

Isosalipurpol,柚皮苷查尔酮,Chalconaringenin,trans-2'4'6'4-tetrahydroxychalcone,柚皮素查耳酮

Others Others
Naringenin chalcone (Isosalipurpol) 是一种黄酮醇生物合成的中间体,在查耳酮异构酶的作用下,自发代谢成柚皮素。它具有抗炎和抗过敏活性。
T0962 L-Hyoscyamine

Daturine,Hyoscyamine,L-莨菪碱,L-天仙子胺

AChR Neuroscience
L-Hyoscyamine (Daturine) 是从山莨菪中提取的一种托烷生物碱,是竞争性的毒蕈碱受体拮抗剂。它是 Atropine 的左旋异构体。
T2O2733 L-Cystine

Cystine Acid,cystine,胱氨酸,L-胱氨酸

Antioxidant; Ferroptosis; Endogenous Metabolite Apoptosis; Metabolism; oxidation-reduction
L-Cystine (Cystine Acid) 是一种从半胱氨酸氨基酸硫醇侧链氧化获得的含硫衍生物。它起到抗氧化剂的作用,保护组织免受辐射和污染,减缓衰老过程。它还有助于蛋白质合成。
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天然产物

Salicin
Cat.No: T0443
Synonym: Salicoside,水杨甙,Salicine,水杨苷,D-(−)-Salicin
Target: COX
Lauroyl lysine
Cat.No: T20476
Synonym: 月桂酰赖氨酸,N6-Lauroyl-L-lysine
Target: Others
Ombuin
Cat.No: TN2010
Synonym: 商陆黄素,商陆素
Target: Antibacterial
Epoxymicheliolide
Cat.No: TQ0234
Synonym: 1β,10β-Epoxymicheliolide,环氧木香内酯
Target: Others
Urocanic acid
Cat.No: T4759
Synonym: 4-Imidazoleacrylic acid,尿刊酸
Target: Others, Endogenous Metabolite
Skatole
Cat.No: T5281
Synonym: 粪臭素,Scatole,3-Methylindole,3-​Methylindole,3-甲基吲哚,3-Methyl-1H-indole,beta-Methylindole
Target: AhR, p38 MAPK, Aryl Hydrocarbon Receptor, Endogenous Metabolite, Antibacterial, Autophagy, Antifungal
Mogrol
Cat.No: TN2346
Synonym:
Target: ERK, AMPK, STAT
Ethyl pyruvate
Cat.No: T8030
Synonym:
Target: Apoptosis, Antioxidant
Azaserine
Cat.No: TQ0158
Synonym: CI-337,偶氮丝胺酸,P-165,氮杂丝氨酸,O-Diazoacetyl-L-serine
Target: Others, Antibiotic
Tiglic acid
Cat.No: T5542
Synonym: 惕格酸,Sabadillic acid,Tiglinic acid,巴豆酸,Cevadic acid
Target: Endogenous Metabolite, HSV
Parthenolide
Cat.No: T2140
Synonym: (-)-Parthenolide,小白菊内酯
Target: Apoptosis, Mitophagy, NF-κB, HDAC, Autophagy
6"-O-Apiosyl-5-O-Methylvisammioside
Cat.No: TQ0240
Synonym:
Target: Others
Cedryl acetate
Cat.No: T2956
Synonym: 乙酸柏木酯,Cedrol acetate,Cedranyl acetate
Target: Antifungal
(20S)-Protopanaxatriol
Cat.No: T2810
Synonym: 原人参三醇,20(S)-APPT,20 (S)-原人参三醇,g-PPT
Target: Apoptosis, Estrogen Receptor/ERR, Glucocorticoid Receptor, Estrogen/progestogen Receptor, Liver X Receptor
Nortriptyline
Cat.No: T73844
Synonym:
Target: Others
L-Asparagine
Cat.No: T2O2774
Synonym: alpha-aminosuccinamic acid,L-天门冬氨酸,(-)-Asparagine,Asparamide,2-Aminosuccinamic acid,Asn,Altheine
Target: Endogenous Metabolite
Bisabolangelone
Cat.No: TN1445
Synonym:
Target: p38 MAPK, MAPK
18α-Glycyrrhetinic acid
Cat.No: T2745
Synonym: 18-α-甘草次酸,甘草次酸,Enoxolone,Glycyrrhetinic acid
Target: Apoptosis, NF-κB, Proteasome
γ-Glu-Gly
Cat.No: T39359
Synonym: gamma-Glutamylglycine
Target: Amino Acids and Derivatives
Alisol B
Cat.No: T5770
Synonym:
Target: RANKL/RANK
Levomefolic Acid
Cat.No: T7094
Synonym: L-5-甲基四氢叶酸,5-MTHF,5-甲基四氢叶酸
Target: Reactive Oxygen Species, Endogenous Metabolite
Flavin adenine dinucleotide disodium salt
Cat.No: T5067
Synonym: Flavin Adenine Dinucleotide Disodium,黄素腺嘌呤二核苷酸二钠,FAD sodium salt,FAD-Na2
Target: Others, Endogenous Metabolite
Emodin-8-glucoside
Cat.No: T3900
Synonym: 大黄素-8-β-D-吡喃葡萄糖苷,Emodin glucoside B,Anthraglycoside B
Target: Others
Cholesteryl Acetate
Cat.No: T2918
Synonym: Cholesterin acetate,胆甾醇乙酸酯,Cholesterol acetate,Acebrochol
Target: Others
Bacopaside I
Cat.No: TN1420
Synonym:
Target: Others
Nicotinamide riboside chloride
Cat.No: T6220
Synonym: 烟酰胺核糖氯酸盐,烟酰胺核苷
Target: Sirtuin, Endogenous Metabolite
PALATINOSE
Cat.No: TN6745
Synonym: TNP-470,帕拉金糖水合物,Isomaltulose
Target: Others
β-Glycerophosphate disodium salt hydrate
Cat.No: T4915
Synonym:
Target: Phosphatase, Endogenous Metabolite
L-Ascorbic acid
Cat.No: T0928
Synonym: 维生素C,Vitamin C,Ascorbic acid,L(+)-Ascorbic acid,抗坏血酸,L-Ascorbate
Target: Apoptosis, Calcium Channel, Reactive Oxygen Species, Endogenous Metabolite
1-Octanol
Cat.No: T10024
Synonym: Octanol,正辛醇
Target: Calcium Channel, Endogenous Metabolite
DL-Methionine
Cat.No: TJO2742
Synonym: 蛋氨酸,methionine,DL-蛋氨酸,Acimetion,Racemethionine
Target: Parasite
Tigloylgomisin H
Cat.No: TN2272
Synonym:
Target: Nrf2
Atropine
Cat.No: T0375
Synonym: DL-Hyoscyamine,阿托品,Tropine tropate,颠茄碱
Target: Endogenous Metabolite, AChR
Norisoboldine
Cat.No: T5S1895
Synonym: Laurelliptine,去甲异波尔定,(+)-Laurelliptine
Target: MAPK, Adenosine Receptor
(-)-Menthol
Cat.No: T1407
Synonym: L-Menthol,Levomenthol,(-)-薄荷醇,薄荷冰,Menthomenthol,Menthacamphor
Target: Opioid Receptor, Endogenous Metabolite, TRP/TRPV Channel
Fosfructose
Cat.No: T3228
Synonym: D-fructose-1,6-diphosphate,Betulanonaprenol,4937-84-2,Diphosphofructose,二磷酸果糖,Fructose 1,6-diphosphate,D-fructofuranose 1,6-bisphosphate,Esafosfan
Target: Others, Endogenous Metabolite
Proteinase
Cat.No: T19529
Synonym:
Target: Others
Paraxanthine
Cat.No: T4973
Synonym: 1,7-二甲基黄嘌呤,1,7-DIMETHYLXANTHINE
Target: Endogenous Metabolite
Atractylenolide I
Cat.No: T5S0167
Synonym: 白术内酯 I,白术内酯I;苍术内酯I
Target: IL Receptor, TNF, TLR, JAK, STAT
Mithramycin A
Cat.No: T5530
Synonym: Plicamycin
Target: DNA/RNA Synthesis
Nosiheptide
Cat.No: T16340
Synonym: RP 9671,Multhiomycin,那西肽
Target: Antibacterial, Antibiotic
L-Leucine
Cat.No: T3O2749
Synonym: (S)-Leucine,Leu,L-亮氨酸,亮氨酸
Target: mTOR
Fraxetin
Cat.No: T2909
Synonym: 7,8-dihydroxy-6-methoxy coumarin,秦皮素,弗拉西汀
Target: Apoptosis, Others
Vitamin B12
Cat.No: T1040
Synonym: Cyanocobalamin,Cobalamin,维生素B12
Target: Endogenous Metabolite
D-Pantothenic acid
Cat.No: T6480
Synonym: vitamin B5,pantothenate,D-泛酸
Target: Others
L-Histidine
Cat.No: T2A2532
Synonym: Glyoxaline-5-alanine,L-(-)-Histidine,L-组氨酸,histidine,组氨酸,L-Hisidine
Target: Mitochondrial Metabolism, Endogenous Metabolite
Rauwolscine hydrochloride
Cat.No: T4429
Synonym: Corynanthidine hydrochloride,盐酸育亨宾碱,萝芙素盐酸盐,α-Yohimbine hydrochloride,Isoyohimbine hydrochloride
Target: Adrenergic Receptor
(E)-Naringenin chalcone
Cat.No: T2S2173
Synonym: Isosalipurpol,柚皮苷查尔酮,Chalconaringenin,trans-2'4'6'4-tetrahydroxychalcone,柚皮素查耳酮
Target: Others
L-Hyoscyamine
Cat.No: T0962
Synonym: Daturine,Hyoscyamine,L-莨菪碱,L-天仙子胺
Target: AChR
L-Cystine
Cat.No: T2O2733
Synonym: Cystine Acid,cystine,胱氨酸,L-胱氨酸
Target: Antioxidant, Ferroptosis, Endogenous Metabolite
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Cat. No. Product Name Species Expression System
TMPY-03425 Tau Protein, Human, Recombinant (His)

PPND,FTDP-17,MTBT1,DDPAC,MAPTL,MTBT2,microtubule-associated ...

Human E. coli
MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. Tau protein is a highly soluble microtubule-associated protein (MAP...
TMPJ-01468 pro-Beta NGF Protein, Human, Recombinant

β-NGF,NGF,NGFB,Beta-NGF,Beta-Nerve Growth Factor,pro-Beta NG...

Human E. coli
The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration.
TMPY-05030 PCDH7 Protein, Human, Recombinant (His)

BHPCDH

Human Baculovirus Insect Cells
PCDH7, a member of protocadherins family, functions as tumor suppressor in several human cancers. The human PCDH7 gene is localized in chromosome 4p15, which is often inactivated in human cancers, including bladder cancer. The low PCDH7 expression is a potential prognostic biomarker for primary non-muscle invasive bladder cancer (NMIBC). PCDH7 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 94 kDa and the accession number...
TMPK-00022 Galectin-1 Protein, Human, Recombinant (hFc)

GAL1,LGALS1,Galectin-1,S-Lac lectin 1,DKFZp686E23103,GBP,Gal...

Human HEK293 Cells
Galectin 1 (Gal-1), a β-galactoside binding mammalian lectin of 14KDa, is implicated in many signalling pathways, immune responses associated with cancer progression and immune disorders. Inhibition of human Gal-1 has been regarded as one of the potential therapeutic approaches for the treatment of cancer, as it plays a major role in tumour development and metastasis by modulating various biological functions viz. apoptosis, angiogenesis, migration, cell immune escape.
TMPK-00811 L1CAM Protein, Mouse, Recombinant (His)

CALL,MGC132578,FLJ44930,NCAM-L1,MIC5,CHL-1,SPG1,HSAS,CD171,L...

Mouse HEK293 Cells
L1 cell adhesion molecule (L1CAM) is one of the first neural adhesion molecules described with important functions in the development of the nervous system. Subsequent work discovered that L1CAM is expressed in many human cancers and is often associated with bad prognosis. This is most likely due to the motility and invasion promoting function of L1CAM. L1CAM is a valuable diagnostic/prognostic marker and an attractive target for the therapy of several human cancers.
TMPK-01150 Beta Klotho Protein, Mouse, Recombinant (His)

Klotho beta,β-klotho,MGC142213,βKlotho,β Klotho,KLB,beta-klo...

Mouse HEK293 Cells
Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15/19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, but diverse roles for Klb are now emerging. Central Klb expression is low but discrete and may govern FGF-targeted sites. Beta Klotho Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 109.91 kDa and the acce...
TMPJ-00779 TNF alpha Protein, Rabbit, Recombinant

TNF-a,Tumor Necrosis Factor,TNF-α,TNF α,Cachectin,肿瘤坏死因子,Tum...

Rabbit E. coli
Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor type 2,p75R). TNFα is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNFα is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other ...
TMPJ-00258 TGF beta 2 Protein, Human, Recombinant

Glioblastoma-derived T-cell suppressor factor,TGF-β-2,Transf...

Human HEK293 Cells
Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. Defects in TGFB2 may be...
TMPJ-01464 IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F)

TCGF,Aldesleukin,T-Cell Growth Factor,IL-2,Interleukin-2,IL2

Human HEK293 Cells
Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system,belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages...
TMPY-02525 RGMA Protein, Human, Recombinant (His)

repulsive guidance molecule family member a,RGM

Human HEK293 Cells
RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that form...
TMPJ-00249 TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated

TGF-Beta-1,TGFB1,Transforming Growth Factor β-1,Latency-Asso...

Human HEK293 Cells
Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family...
TMPJ-00842 FGF-2 Protein, Rat, Recombinant

bFGF,Heparin-Binding Growth Factor 2,FGFB,Fibroblast Growth ...

Rat E. coli
FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family. The family constitutes a large family of proteins involved in many aspects of development including cell proliferation, growth, and differentiation. They act on several cell types to regulate diverse physiologic functions including angiogenesis, cell growth, pattern formation, embryonic development, metabolic regulation, cell migration, neurotrophic effects, and tissue repair. FGF-basic is a non-glycosylated heparin binding g...
TMPJ-01471 Activin A Protein, Human, Mouse, Rat, Cynomolgus, Rhesus, Recombinant

Activin A,INHBA,Inhibin beta A chain,Inhibin β A chain

Human/Mouse/Rat HEK293 Cells
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell developm...
TMPJ-00603 TL1A/TNFSF15 Protein, Mouse, Recombinant

TNFSF15,Tumor Necrosis Factor Ligand Superfamily Member 15,V...

Mouse E. coli
Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor of endothelial cell proliferation, angiogenesis and tumor growth. TNFSF15 exerts two activities on endothelial cells: early G1 arrest of G0/G1-cells responding to growth stimuli and programmed cell death of proliferating cells. These activities are highly specific to endothelial ...
TMPJ-00059 IL-7 Protein, Human, Recombinant (His)

Interleukin-7,IL7,白细胞介素,IL-7,白介素

Human HEK293 Cells
Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions as a pre-pro-B cell growth-stimulating factor. Human IL7 cDNA encodes a 177 amino acid precursor protein containing a 25 amino acid signal peptide and a 152 amino acid mature protein. Human and mouse IL7 share 65% sequence identity in the mature region and both exhibit cross-spe...
TMPY-00541 LON PROTEASE Protein, E. coli, Recombinant (His)

E. coli E. coli
Lon protease, an ATP-dependent mitochondrial protease, is important in mitochondrial protein maintenance. Lon protease is a multifunctional enzyme, and its functions include the degradation of damaged proteins and naturally short-lived proteins, ATPase and chaperone-like activities, as well as DNA binding. Lon protease plays a major role in the protein quality control system in mammalian cell mitochondria. It is present in the mitochondrial matrix and degrades oxidized and misfolded proteins, th...
TMPY-00476 ITGB1 Protein, Human, Recombinant (His)

VLAB,integrin, beta 1 (fibronectin receptor, beta polypeptid...

Human HEK293 Cells
ITGB1 (Integrin Subunit Beta 1) is a Protein Coding gene. This gene encodes a beta subunit, which is a type 1 transmembrane protein of the integrin beta chain family. ITGB1 is a heterodimeric cell-surface receptor involved in cell functions such as proliferation, migration, invasion, and survival. ITGB1 has been recognized to play a major role in tumor growth, invasion, and metastasis. Using luciferase assays, the researcher identified ITGB1 as a direct target of miR-134. ITGB1 is a direct targe...
TMPY-03118 ORM2 Protein, Human, Recombinant (His)

AGP-B',ORM2,orosomucoid 2,AGP-B,AGP2

Human HEK293 Cells
ORM2 belongs to the calycin superfamily, lipocalin family. Lipocalins share limited regions of sequence homology and a common tertiary structure architecture. They transport small hydrophobic molecules such as steroids, bilins, retinoids, and lipids. Lipocalins can be found in gram-negative bacteria, vertebrate cells, and invertebrate cells, and plants. They are associated with many biological processes. ORM2 functions as a transport protein in the bloodstream. It is expressed by the liver and s...
TMPY-01850 CEACAM3 Protein, Human, Recombinant (His)

W282,W264,CEA,CD66D,CGM1,MGC119875,carcinoembryonic antigen ...

Human HEK293 Cells
CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66a, CD66b, CD66c, and CD66d. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression, angiogenesis, and neutrophil activation. Abnormal overexp...
TMPY-02953 TEM8/ANTXR1 Protein, Human, Recombinant (hFc)

ATR,TEM8,anthrax toxin receptor 1,GAPO

Human HEK293 Cells
ANTXR1 contains 1 VWFA domain and belongs to the ATR family. ATR (Ataxia telangiectasia and Rad3 related) and ATM (Ataxia telangiectasia mutated) are closely related kinases that are activated by DNA damage. They are serine-threonine protein kinases and belongs to the phosphatidylinositol 3' kinase-like kinase (PIKK) family. Upon recruitment by the DNA damage binding proteins/complexes (ATRIP for ATR; MRN for ATM), ATM/ATR initiate the DNA damage checkpoint by phosphorylating a number of key pro...
TMPY-05004 FGF-4 Protein, Human, Recombinant

HST-1,KFGF,fibroblast growth factor 4,HSTF1,K-FGF,HST,HBGF-4

Human E. coli
FGF (fibroblast growth factor) signalling is known to be required for many aspects of mesoderm formation and patterning during Xenopus development and has been implicated in regulating genes required for the specification of both blood and skeletal muscle lineages. Fibroblast growth factor 4 (FGF4) signaling induces differentiation from embryonic stem cells (ESCs) via the phosphorylation of downstream molecules such as mitogen-activated protein kinase/extracellular signal-related kinase (MEK) a...
TMPY-05510 BDNF Protein, Mouse, Recombinant (His)

brain-derived neurotrophic factor

Mouse HEK293 Cells
BDNF is a member of thenerve growth factorfamily. It is highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. It also can be detected in heart, lung, skeletal muscle, testis, prostate and placenta. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. During development, BDNF promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. It participates in axonal growth,...
TMPY-02115 R-Spondin 3/RSPO3 Protein, Human, Recombinant (aa 1-146, His)

CRISTIN1,THSD2,R-spondin 3,PWTSR

Human HEK293 Cells
R-spondin 3 (RSPO3) is a member of the R-Spondin (RSPO) family in vertebrates that activate Wnt/beta-catenin signaling, plays a key role in these processes. The RSPO family of secreted Wnt modulators is involved in development and disease and holds therapeutic promise as stem cell growth factors. The four members have high structural homology. RSPO2 and RSPO3 are more potent than RSPO1, whereas RSPO4 is relatively inactive. All RSPO members require Wnt ligands and LRP6 for activity and amplify s...
TMPJ-00137 APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)

TRDL-1,TNF- and APOL-related leukocyte expressed ligand 2,Tu...

Human HEK293 Cells
APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. Secreted human APRIL, which consists almost entirely of a single TNF homology domain, shares 85% amino acid sequence identity with mouse and rat APRIL. Both APRIL and its close relative BAFF bind and signal through the TNF superfamily recept...
TMPY-02543 PCNA Protein, Human, Recombinant (His)

ATLD2,proliferating cell nuclear antigen

Human Baculovirus Insect Cells
Proliferating Cell Nuclear Antigen (PCNA) is a protein only expressed in normal proliferate cells and cancer cells. It is central to both DNA replication and repair. One of the well-established functions for PCNA is its role as the processivity factor for DNA polymerase delta and epsilon. PCNA tethers the polymerase catalytic unit to the DNA template for rapid and processive DNA synthesis. Two forms of PCNA exist in cells: (i) a detergent-insoluble trimeric form stably associated with the replic...
TMPJ-00387 IL-4R alpha Protein, Mouse, Recombinant (hFc)

Soluble IL-4R-alpha,Interleukin-4 receptor subunit alpha,Sol...

Mouse HEK293 Cells
Interleukin-4 receptor subunit alpha(IL-4RA), alos known as Soluble IL-4 receptor subunit alpha, belongs to the type I cytokine receptor family and type 4 subfamily. It expressed in both Th1 and Th2 cells. It functions as receptor for both interleukin 4 and interleukin 13 and couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and chemokine and mucus production at sites of allergic ...
TMPJ-00051 IL-3 Protein, Mouse, Recombinant (His)

Mast cell growth factor,Il3,Multipotential colony-stimulatin...

Mouse HEK293 Cells
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. In addition, IL-3 also affects the functional activity of mature mast cells, basophils, eosinophils and macrophages.Because of its multiple functions and targets, it was originally studied under different names, including mast cell growth factor P-cell stimulating factor, bu...
TMPY-02700 BCL2 Protein, Human, Recombinant (His)

Bcl-2,PPP1R50,B-cell CLL/lymphoma 2

Human E. coli
BCL2 (B-cell leukemia/lymphoma 2, N-Histidine-tagged), also known as Bcl-2, belongs to the Bcl-2 family. Bcl-2 family proteins regulate and contribute to programmed cell death or apoptosis. It is a large protein family and all members contain at least one of four BH (bcl-2 homology) domains. Certain members such as Bcl-2, Bcl-xl and Mcl1 are anti-apoptotic, whilst others are pro-apoptotic. Most Bcl-2 family members contain a C-terminal transmembrane domain that functions to target these proteins...
TMPY-06981 IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)

interleukin 1 α,IL1,白介素,IL-1F1,IL1-α,IL-1A,IL1F1,白细胞介素,IL-1 ...

Human E. coli
IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophage...
TMPJ-00042 TSLP Protein, Human, Recombinant

TSLP,Thymic stromal lymphopoietin

Human E. coli
Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino acids (aa) signal sequence and 131 aa mature region. Human TSLP has two isoforms lfTSLP and sfTSLP produced by alternative splicing . lfTSLP is expressed in a number of tissues including heart, liver and prostate, and sfTSLP (63aa) is predominantly expressed in keratinocytes of oral...
TMPY-01806 CD9 Protein, Human, Recombinant (His)

BTCC-1,DRAP-27,TSPAN29,MRP-1,CD9 molecule,MIC3,TSPAN-29

Human HEK293 Cells
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d...
TMPY-02219 Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His)

NS1 Protein

H1N1 E. coli
The NS1 Influenza protein is created by the internal protein-encoding, linear negative-sense, single-stranded RNA, NS gene segment and which also codes for the nuclear export protein or NEP, formerly referred to as the NS2 protein, which mediates the export of vRNPs. The non-structural (NS1) protein is found in Influenzavirus A, Influenzavirus B, and Influenzavirus C. The non-structural (NS1) protein of the highly pathogenic avian H5N1 viruses circulating in poultry and waterfowl in Southeast As...
TMPY-04396 C-ABL/ABL1 Protein, Human, Recombinant (GST)

v-abl,ABL,JTK7,ABL proto-oncogene 1, non-receptor tyrosine k...

Human Baculovirus Insect Cells
c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cytosol, and c-Abl is present in the nucleus as well. c-Abl is a non-receptor tyrosine kinase that participates in multiple signaling pathways linking the cell surface, cytoskeleton, and the nucleus. Recent in vitro studies have also linked c-Abl to amyloid-beta-induced toxicity an...
TMPH-02858 Wnt2 Protein, Mouse, Recombinant (His)

Protein Wnt-2,INT-1-related protein,Wnt2

Mouse E. coli
Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway. Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons.
TMPH-00788 PYP Protein, Halochromatium salexigens, Recombinant (His)

pyp,Photoactive yellow protein

Halochromatium salexigens E. coli
Photoactive blue light protein. Probably functions as a photoreceptor for a negative phototaxis response.
TMPH-00515 PPDK Protein, Entamoeba histolytica, Recombinant (His & SUMO)

PPDK,Pyruvate, orthophosphate dikinase,Pyruvate, phosphate d...

Entamoeba histolytica E. coli
Catalyzes the reversible phosphorylation of pyruvate and phosphate. In E.histolytica and C.symbiosus, PPDK functions in the direction of ATP synthesis.
TMPJ-01016 INHBC Protein, Human, Recombinant (N-His)

Activin Beta-C Chain,INHBC,Inhibin β C Chain,Activin β-C Cha...

Human E. coli
Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins,Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary...
TMPY-04559 CDC42BPB Protein, Human, Recombinant (His & GST)

CDC42 binding protein kinase beta (DMPK-like),MRCKB,CDC42 bi...

Human Baculovirus Insect Cells
CDC42BPB is a member of the serine / threonine protein kinase family that contains a Cdc42 / Rsc-binding p21 binding domain similar to that of PAK kinase. The kinase domain of this protein is related to the myotonic dystrophy kinase related ROK and this kinase may have functions in downstream regulating of Cdc42 in cytoskeletal recognization. It has been reported that the CDC42BPB protein take part in regulating numerous cellular functions by binding to members of a serine / threonine protein ki...
TMPK-00356 IL-27RA/TCCR Protein, Human, Recombinant (His)

WSX1,IL-27 RA,IL27R α,CRL1,IL27RA,IL27R alpha,IL-27R-alpha,W...

Human HEK293 Cells
IL-27Ra (also known as TCCR and WSX1) as a gene whose expression can induce the transformation of hematopoietic cells. IL-27Ra (IL-27R) is a type I cytokine receptor that functions as the ligand binding component of the receptor for IL-27 and functions with the glycoprotein 130 (gp130) coreceptor to induce signal transduction in response to IL-27.
TMPH-00682 Trigger factor Protein, E. coli O157:H7, Recombinant (Avi & His & MBP), Biotinylated

tig,PPIase,Trigger factor

E. coli E. coli
Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.
TMPJ-01157 LACTB2 Protein, Human, Recombinant (GST)

β-Lactamase-Like Protein 2,LACTB2,Beta-Lactamase-Like Protei...

Human E. coli
β-Lactamase-like Protein 2 (LACTB2) is a number of the metallo-beta-lactamase superfamily.LACTB2 also belongs to the Glyoxalase II family. LACTB2 is 288 amino acids long with 8 zinc-binding domains. The LACTB2 gene is expressed at high levels and annotates structural defects or features in 4 cDNA clones. LACTB2 proteins are expected to have hydrolase activity and metal ion-binding functions. LACTB2 protein is found to localize in mitochondrion. Other functions of LACTB2 is yet unknown.
TMPH-02303 Vasculin Protein, Human, Recombinant (His & SUMO)

GC-rich promoter-binding protein 1,Vasculin,GPBP1,Vascular w...

Human E. coli
Functions as a GC-rich promoter-specific transactivating transcription factor. Vasculin Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 36.8 kDa and the accession number is Q86WP2.
TMPK-00920 IL-1 alpha/IL-1A Protein, Cynomolgus, Recombinant (His)

IL-1A,白介素,IL-1 alpha,Interleukin-1 alpha,IL-1 α,IL1α,Interle...

Cynomolgus HEK293 Cells
The interleukin (IL)-1 family of cytokines is currently comprised of 11 members that have pleiotropic functions in inflammation and cancer. IL-1α and IL-1β were the first members of the IL-1 family to be described, and both signal via the same receptor, IL-1R. Over the last decade, much progress has been made in our understanding of biogenesis of IL-1β and its functions in human diseases.
TMPH-03041 IHF-alpha Protein, MenB, Recombinant (His)

Integration host factor subunit alpha,ihfA

MenB E. coli
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
TMPH-01530 INHBA Protein, Human, Recombinant (His & SUMO)

Activin beta-A chain,INHBA,Inhibin beta A chain,Erythroid di...

Human E. coli
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of a...
TMPH-00033 ASFV (strain Ba71V) p30 Protein (His)

Ba71V-93,Phosphoprotein p30,p30,CP204L,Phosphoprotein p32

ASFV E. coli
Modifies the subcellular distribution of heterogeneous nuclear ribonucleoprotein K (HNRNPK) and may contribute to modulate HNRNPK functions related to processing and export of mRNAs during ASFV infection.
TMPH-00546 Epstein-Barr virus (strain GD1) BARF1 Protein (His)

33 kDa early protein,BARF1,p33,Secreted protein BARF1

EBV E. coli
Plays diverse functions in immunomodulation and oncogenicity, maybe by acting as a functional receptor for human CSF1. May inhibit interferon secretion from mononuclear cells. Exhibits oncogenic activity in vitro.
TMPK-00876 G-CSFR/CD114 Protein, Mouse, Recombinant (His)

CD114,G CSF R,G-CSF-R,G-CSF R,CSF3R,GCSFR,Csfgr

Mouse HEK293 Cells
The Granulocyte Colony-Stimulating Factor (G-CSF) receptor, a member of the hematopoietin cytokine receptor superfamily, functions as a homodimer and requires the recruitment of cytosolic protein tyrosine kinases (PTKs) to transduce its signal.
TMPH-02685 GPHB5 Protein, Mouse, Recombinant (His & Myc)

Glycoprotein hormone beta-5,Thyrostimulin subunit beta,Gphb5

Mouse E. coli
Functions as a heterodimeric glycoprotein hormone with GPHA2 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid cell metabolism.
TMPH-00662 Trigger factor Protein, E. coli O127:H6, Recombinant (His)

tig,PPIase,Trigger factor

E. coli P. pastoris (Yeast)
Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.
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重组蛋白

Tau Protein, Human, Recombinant (His)
Cat.No: TMPY-03425
Species: Human
Expression System: E. coli
pro-Beta NGF Protein, Human, Recombinant
Cat.No: TMPJ-01468
Species: Human
Expression System: E. coli
PCDH7 Protein, Human, Recombinant (His)
Cat.No: TMPY-05030
Species: Human
Expression System: Baculovirus Insect Cells
Galectin-1 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00022
Species: Human
Expression System: HEK293 Cells
L1CAM Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00811
Species: Mouse
Expression System: HEK293 Cells
Beta Klotho Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01150
Species: Mouse
Expression System: HEK293 Cells
TNF alpha Protein, Rabbit, Recombinant
Cat.No: TMPJ-00779
Species: Rabbit
Expression System: E. coli
TGF beta 2 Protein, Human, Recombinant
Cat.No: TMPJ-00258
Species: Human
Expression System: HEK293 Cells
IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F)
Cat.No: TMPJ-01464
Species: Human
Expression System: HEK293 Cells
RGMA Protein, Human, Recombinant (His)
Cat.No: TMPY-02525
Species: Human
Expression System: HEK293 Cells
TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated
Cat.No: TMPJ-00249
Species: Human
Expression System: HEK293 Cells
FGF-2 Protein, Rat, Recombinant
Cat.No: TMPJ-00842
Species: Rat
Expression System: E. coli
Activin A Protein, Human, Mouse, Rat, Cynomolgus, Rhesus, Recombinant
Cat.No: TMPJ-01471
Species: Human/Mouse/Rat
Expression System: HEK293 Cells
TL1A/TNFSF15 Protein, Mouse, Recombinant
Cat.No: TMPJ-00603
Species: Mouse
Expression System: E. coli
IL-7 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00059
Species: Human
Expression System: HEK293 Cells
LON PROTEASE Protein, E. coli, Recombinant (His)
Cat.No: TMPY-00541
Species: E. coli
Expression System: E. coli
ITGB1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00476
Species: Human
Expression System: HEK293 Cells
ORM2 Protein, Human, Recombinant (His)
Cat.No: TMPY-03118
Species: Human
Expression System: HEK293 Cells
CEACAM3 Protein, Human, Recombinant (His)
Cat.No: TMPY-01850
Species: Human
Expression System: HEK293 Cells
TEM8/ANTXR1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02953
Species: Human
Expression System: HEK293 Cells
FGF-4 Protein, Human, Recombinant
Cat.No: TMPY-05004
Species: Human
Expression System: E. coli
BDNF Protein, Mouse, Recombinant (His)
Cat.No: TMPY-05510
Species: Mouse
Expression System: HEK293 Cells
R-Spondin 3/RSPO3 Protein, Human, Recombinant (aa 1-146, His)
Cat.No: TMPY-02115
Species: Human
Expression System: HEK293 Cells
APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)
Cat.No: TMPJ-00137
Species: Human
Expression System: HEK293 Cells
PCNA Protein, Human, Recombinant (His)
Cat.No: TMPY-02543
Species: Human
Expression System: Baculovirus Insect Cells
IL-4R alpha Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00387
Species: Mouse
Expression System: HEK293 Cells
IL-3 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00051
Species: Mouse
Expression System: HEK293 Cells
BCL2 Protein, Human, Recombinant (His)
Cat.No: TMPY-02700
Species: Human
Expression System: E. coli
IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)
Cat.No: TMPY-06981
Species: Human
Expression System: E. coli
TSLP Protein, Human, Recombinant
Cat.No: TMPJ-00042
Species: Human
Expression System: E. coli
CD9 Protein, Human, Recombinant (His)
Cat.No: TMPY-01806
Species: Human
Expression System: HEK293 Cells
Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His)
Cat.No: TMPY-02219
Species: H1N1
Expression System: E. coli
C-ABL/ABL1 Protein, Human, Recombinant (GST)
Cat.No: TMPY-04396
Species: Human
Expression System: Baculovirus Insect Cells
Wnt2 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02858
Species: Mouse
Expression System: E. coli
PYP Protein, Halochromatium salexigens, Recombinant (His)
Cat.No: TMPH-00788
Species: Halochromatium salexigens
Expression System: E. coli
PPDK Protein, Entamoeba histolytica, Recombinant (His & SUMO)
Cat.No: TMPH-00515
Species: Entamoeba histolytica
Expression System: E. coli
INHBC Protein, Human, Recombinant (N-His)
Cat.No: TMPJ-01016
Species: Human
Expression System: E. coli
CDC42BPB Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04559
Species: Human
Expression System: Baculovirus Insect Cells
IL-27RA/TCCR Protein, Human, Recombinant (His)
Cat.No: TMPK-00356
Species: Human
Expression System: HEK293 Cells
Trigger factor Protein, E. coli O157:H7, Recombinant (Avi & His & MBP), Biotinylated
Cat.No: TMPH-00682
Species: E. coli
Expression System: E. coli
LACTB2 Protein, Human, Recombinant (GST)
Cat.No: TMPJ-01157
Species: Human
Expression System: E. coli
Vasculin Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-02303
Species: Human
Expression System: E. coli
IL-1 alpha/IL-1A Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00920
Species: Cynomolgus
Expression System: HEK293 Cells
IHF-alpha Protein, MenB, Recombinant (His)
Cat.No: TMPH-03041
Species: MenB
Expression System: E. coli
INHBA Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01530
Species: Human
Expression System: E. coli
ASFV (strain Ba71V) p30 Protein (His)
Cat.No: TMPH-00033
Species: ASFV
Expression System: E. coli
Epstein-Barr virus (strain GD1) BARF1 Protein (His)
Cat.No: TMPH-00546
Species: EBV
Expression System: E. coli
G-CSFR/CD114 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00876
Species: Mouse
Expression System: HEK293 Cells
GPHB5 Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02685
Species: Mouse
Expression System: E. coli
Trigger factor Protein, E. coli O127:H6, Recombinant (His)
Cat.No: TMPH-00662
Species: E. coli
Expression System: P. pastoris (Yeast)
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Cat. No. Product Name Target Signaling Pathways
T11250 Ezetimibe-d4

SCH 58235 D4

Others Others
Ezetimibe D4, a deuterium-labeled variant of Ezetimibe, functions as an inhibitor of Niemann-Pick C1-like1 (NPC1L1) and is recognized for its potent activation of Nrf2.
T12442 Phenindione D5

Rectadione D5,苯茚二酮 D5

Others Others
Phenindione D5 is deuterium labeled Phenindione, which functions as a Vitamin K antagonist.
T11814 Lamivudine 13C,15N2

Others Others
Lamivudine 13C,15N2, an impurity of Lamivudine (BCH-189), functions as an inhibitor of both HIV-1/2 reverse transcriptase and hepatitis B virus reverse transcriptase, classifying it as a nucleoside reverse transcriptase inhibitor (NRTIs).
T11754 Ketorolac-d5

Ketorolac D5

PPAR DNA Damage/DNA Repair; Metabolism
Ketorolac D5, a deuterium-labeled version of Ketorolac, is a non-steroidal anti-inflammatory agent that functions as a nonselective COX inhibitor. It exhibits IC50 values of 20 nM for COX-1 and 120 nM for COX-2.
T11870 Losartan D4

氯沙坦 D4,DuP-753 D4

Others Others
Losartan D4, the deuterium-labeled version of Losartan, functions as an angiotensin II receptor antagonist. It inhibits the interaction between angiotensin II and AT1 receptors by competing for binding, achieving an IC50 value of 20 nM.
T73716 Miglustat-d9 HCl

Miglustat-d9 (hydrochloride)为Miglustat (hydrochloride)的氘代物,属于葡萄糖神经酰胺合成酶抑制剂,主要用于治疗I型戈谢病。
TMIH-0342 Metolazone-d7

Metolazone-d7 是 Metolazone 的氘代化合物。Metolazone 的 CAS 号为 17560-51-9。Metolazone 具有抗心力衰竭和高血压作用。
T11240 Ethacrynic acid D5

Others Others
Ethacrynic acid, a diuretic, functions as an inhibitor of L-type voltage-dependent and store-operated calcium channels, facilitating the relaxation of airway smooth muscle (ASM) cells. It exhibits anti-inflammatory effects, notably reducing retinoid-induced ear edema in mice, and inhibits glutathione S-transferases (GSTs), making it a potent suppressor of the NF-kB signaling pathway. Additionally, ethacrynic acid modulates leukotriene formation. A variant, Ethacrynic acid D5, is distinguished by...
TMIH-0001 (+/-)-Venlafaxine-d6 HCl

(+/-)-Venlafaxine-d6 HCl 是 (+/-)-Venlafaxine HCl 的氘代化合物。(+/-)-Venlafaxine HCl 的 CAS 号为 99300-78-4。Venlafaxine hydrochloride 是一种口服有效的 5-羟色胺 (5-HT)/去甲肾上腺素 (NE) 重摄取的双重抑制剂,具有抗抑郁活性。
TMIJ-0239 Cobicistat-d8

Cobicistat-d8 是 Cobicistat 的氘代化合物。Cobicistat 的 CAS 号为 1004316-88-4。Cobicistat 是一种细胞色素酶P450 3A 的选择性抑制剂,IC50值为30-285 nM。它是一种药代动力学增强剂,可增强抗 HIV 药物的吸收。
TMIJ-0237 Ascorbic acid-13C6

Ascorbic acid-13C6 是 Ascorbic acid 的 13C 的标记化合物。Ascorbic acid 的 CAS 号为 50-81-7。L-Ascorbic acid是一种电子供体,是一种内源性抗氧化剂。它选择性抑制 Cav3.2 通道,IC50为 6.5 μM。它还是一种胶原沉积促进剂和弹性生成抑制剂,可对抗细菌感染、解毒反应和胶原蛋白的形成。
TMIJ-0112 Aripiprazole-d8

Aripiprazole-d8 是 Aripiprazole 的氘代化合物。Aripiprazole 的 CAS 号为 129722-12-9。Aripiprazole 是血清素受体 5-HT1A 和多巴胺 D2 受体的部分激动剂,还用作突触后拮抗剂和血清素受体 5-HT2A 的拮抗剂。
TMIJ-0378 L-Ascorbic Acid-13C6

L-Ascorbic Acid-13C6 是 L-Ascorbic Acid 的 13C 的标记化合物。L-Ascorbic Acid 的 CAS 号为 50-81-7。L-Ascorbic acid是一种电子供体,是一种内源性抗氧化剂。它选择性抑制 Cav3.2 通道,IC50为 6.5 μM。它还是一种胶原沉积促进剂和弹性生成抑制剂,可对抗细菌感染、解毒反应和胶原蛋白的形成。
TMIJ-0375 Levomefolic Acid-13C-d3

Levomefolic Acid-13C-d3 是 Levomefolic Acid 的 13C 和氘代化合物。Levomefolic Acid 的 CAS 号为 31690-09-2。Levomefolic acid是一种具有口服活性、可穿过血脑屏障的天然活性叶酸,是广泛使用的叶酸食品补充剂。
TMID-0258 (±)-Atropine-d3 (N-methyl-d3)

(±)-Atropine-d3 (N-methyl-d3) 是 (±)-Atropine 的氘代化合物。(±)-Atropine 的 CAS 号为 51-55-8。Atropine 是竞争性的毒蕈碱乙酰胆碱受体拮抗剂,有抗近视效果。它是一种从颠茄植物中分离出来的天然生物碱,可阻断乙酰胆碱对心率和收缩力的抑制作用。
TMIJ-0374 L-Leucine-d3

L-Leucine-d3 是 L-Leucine 的氘代化合物。L-Leucine 的 CAS 号为 61-90-5。L-Leucine 是必需的支链氨基酸,能够激活mTOR信号通路。
TMID-0262 Lidocaine-d10 (N,N-diethyl-d10)

Lidocaine-d10 (N,N-diethyl-d10) 是 Lidocaine 的氘代化合物。Lidocaine 的 CAS 号为 137-58-6。Lidocaine是一种酰胺衍生物,抑制涉及复杂电压和依赖性的钠通道,可用于研究室性心律失常。它通过调节 miR-145 表达和进一步抑制MEK/ERK和NF-κB信号通路来减少胃癌细胞的生长,迁移和侵袭。
T36149 13C C16 Sphingomyelin (d18:1/16:0)

13C C16 Sphingomyelin is an isotopically enriched form of C16 sphingomyelin with carbon-13 occurring on the fatty acid portion. It is intended for use as an internal standard for the quantification of C16 sphingomyelin by GC- or LC-MS. C16 Sphingomyelin is a form of sphingomyelin containing palmitate (16:0) at the variable acylation position. It is the most common form of sphingomyelin found in eggs and is less abundant in the brain and in milk. C16 Sphingomyelin interacts with cholesterol in or...
TMIJ-0081 L-Leucine-d10

L-Leucine-d10 是 L-Leucine 的氘代化合物。L-Leucine 的 CAS 号为 61-90-5。L-Leucine 是必需的支链氨基酸,能够激活mTOR信号通路。
TMIH-0314 Lurasidone-d8 HCl

Lurasidone-d8 HCl 是 Lurasidone HCl 的氘代化合物。Lurasidone HCl 的 CAS 号为 367514-88-3。Lurasidone hydrochloride 是多巴胺 D2和5-HT7的拮抗剂,IC50值分别为 1.68 和 0.495 nM,用于治疗精神分裂症和双相情感障碍。它也是5-HT1A受体的部分激动剂,IC50值为 6.75 nM。
T35790 Palmitic acid-1,2,3,4-13C4

Palmitic Acid-13C (C1, C2, C3, and C4 labeled)

Palmitic acid-13C (C1, C2, C3, and C4 labeled) is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively.1,2Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid bilayer and trafficking of intracellula...
TMIJ-0384 L-Cysteine-d3

L-Cysteine-d3 是 L-Cysteine 的氘代化合物。L-Cysteine 的 CAS 号为 52-90-4。L-Cysteine 是人体非必需的含硫氨基酸。L-Cysteine 对蛋白质合成、解毒和多种代谢功能很重要。L-Cysteine 存在于指甲、皮肤和头发的主要蛋白质-角蛋白中,对胶原蛋白的生成、皮肤弹性和质地都很重要。L-Cysteine 是抗氧化剂谷胱甘肽的一种成分,在辅酶A、肝素和生物素等基本生化物质的代谢中起着重要作用,也是氨基酸牛磺酸的制造所必需的。

同位素标记化合物

Ezetimibe-d4
Cat.No: T11250
Synonym: SCH 58235 D4
Target: Others
Phenindione D5
Cat.No: T12442
Synonym: Rectadione D5,苯茚二酮 D5
Target: Others
Lamivudine 13C,15N2
Cat.No: T11814
Synonym:
Target: Others
Ketorolac-d5
Cat.No: T11754
Synonym: Ketorolac D5
Target: PPAR
Losartan D4
Cat.No: T11870
Synonym: 氯沙坦 D4,DuP-753 D4
Target: Others
Miglustat-d9 HCl
Cat.No: T73716
Synonym:
Target:
Metolazone-d7
Cat.No: TMIH-0342
Synonym:
Target:
Ethacrynic acid D5
Cat.No: T11240
Synonym:
Target: Others
(+/-)-Venlafaxine-d6 HCl
Cat.No: TMIH-0001
Synonym:
Target:
Cobicistat-d8
Cat.No: TMIJ-0239
Synonym:
Target:
Ascorbic acid-13C6
Cat.No: TMIJ-0237
Synonym:
Target:
Aripiprazole-d8
Cat.No: TMIJ-0112
Synonym:
Target:
L-Ascorbic Acid-13C6
Cat.No: TMIJ-0378
Synonym:
Target:
Levomefolic Acid-13C-d3
Cat.No: TMIJ-0375
Synonym:
Target:
(±)-Atropine-d3 (N-methyl-d3)
Cat.No: TMID-0258
Synonym:
Target:
L-Leucine-d3
Cat.No: TMIJ-0374
Synonym:
Target:
Lidocaine-d10 (N,N-diethyl-d10)
Cat.No: TMID-0262
Synonym:
Target:
13C C16 Sphingomyelin (d18:1/16:0)
Cat.No: T36149
Synonym:
Target:
L-Leucine-d10
Cat.No: TMIJ-0081
Synonym:
Target:
Lurasidone-d8 HCl
Cat.No: TMIH-0314
Synonym:
Target:
Palmitic acid-1,2,3,4-13C4
Cat.No: T35790
Synonym: Palmitic Acid-13C (C1, C2, C3, and C4 labeled)
Target:
L-Cysteine-d3
Cat.No: TMIJ-0384
Synonym:
Target:
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