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Cirazoline hydrochloride is a competitive full agonist of the α1A-adrenergic receptor (α1A-AR; Ki: 120 nM). It is a partial agonist at α1B-AR (Ki: 960 nM) and α1D-AR (Ki: 660 nM).
Cirazoline hydrochloride is a competitive full agonist of the α1A-adrenergic receptor (α1A-AR; Ki: 120 nM). It is a partial agonist at α1B-AR (Ki: 960 nM) and α1D-AR (Ki: 660 nM).
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
2 mg | ¥ 1,610 | 5日内发货 | |
5 mg | ¥ 2,730 | 5日内发货 | |
25 mg | ¥ 7,690 | 6-8周 | |
50 mg | ¥ 9,990 | 6-8周 | |
100 mg | ¥ 15,500 | 6-8周 |
产品描述 | Cirazoline hydrochloride is a competitive full agonist of the α1A-adrenergic receptor (α1A-AR; Ki: 120 nM). It is a partial agonist at α1B-AR (Ki: 960 nM) and α1D-AR (Ki: 660 nM). |
体外活性 | Cirazoline hydrochloride (5-10 μM; 24 hours) does not alter GIC survival. And it counteracted only poorly prazosin‐induced GIC death[1]. |
体内活性 | Cirazoline hydrochloride (drinking water; 40 μM; 9 months) shows significantly decreased immobility in the TST. However, it enhances neurogenesis in the mouse [1]. |
别名 | LD 3098 hydrochloride |
分子量 | 252.74 |
分子式 | C13H17ClN2O |
CAS No. | 40600-13-3 |
密度 | 1.25g/cm3 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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